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Eriksson Evert A EA Medical University of South Carolina, Charleston, SC. Electronic address: - - 2014
Little is known about the incidence and etiology of fat embolism in pediatric patients. We sought to determine the incidence, time course, and associated factors of pulmonary fat embolism (PFE), cerebral fat embolism (CFE), and kidney fat embolism (KFE) in trauma and nontrauma pediatric patients at the time of autopsy. ...
Tomizawa Minoru M Department of Gastroenterology, National Hospital Organization Shimoshizu Hospital, Yotsukaido, Chiba 284-0003, - - 2014
The aim of the present study was to reveal the metabolic disorders most commonly associated with nonalcoholic fatty liver disease (NAFLD). Triglyceride (TG), high-density lipoprotein cholesterol (HDL), low-density lipoprotein cholesterol (LDL), blood glucose (BG) and hemoglobin A1c (HbA1c) were analyzed. NAFLD was diagnosed using abdominal ultrasound (US), and TG, HDL, ...
Messier Stephen P SP 1Department of Health and Exercise Science, Wake Forest University, Winston-Salem, NC; 2Department of Biostatistical Sciences, Wake Forest School of Medicine, Wake Forest University, Winston-Salem, NC; 3Section on Gerontology and Geriatric Medicine, Wake Forest School of Medicine, Wake Forest University, Winston-Salem, NC; 4Department of Exercise and Sport Science, East Carolina University, Greenville, NC; 5Department of Radiology, Wake Forest School of Medicine, Wake Forest University, Winston-Salem, NC; 6Department of Rheumatology, Royal North Shore Hospital and Kolling Institute, University of Sydney, Sydney, AUSTRALIA; 7Section on Molecular Medicine, Wake Forest School of Medicine, Wake Forest University, Winston-Salem, NC; and 8Department of Rheumatology and Immunology, Wake Forest School of Medicine, Wake Forest University, Winston-Salem, - - 2014
Using three separate models that included total body mass, total lean and total fat mass, and abdominal and thigh fat as independent measures, we determined their association with knee joint loads in older overweight and obese adults with knee osteoarthritis (OA). Fat depots were quantified using computed tomography, and total ...
Qi Qibin Q Department of Epidemiology, Albert Einstein College of Medicine, Bronx, New York, United States of America Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, United States of - - 2014
FTO is the strongest known genetic susceptibility locus for obesity. Experimental studies in animals suggest the potential roles of FTO in regulating food intake. The interactive relation among FTO variants, dietary intake, and body mass index (BMI) are complex and results from previous often small-scale studies in humans are highly ...
Roswall Nina N From the Danish Cancer Society Research Center, Copenhagen, Denmark (NR, JH, and AT); the Institute of Preventive Medicine, Bispebjerg and Frederiksberg Hospitals-The Capital Region, Copenhagen, Denmark (LÄ, SCL, and TIAS); the Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, University of Copenhagen, Copenhagen, Denmark (TSA and TIAS); the Copenhagen Prospective Studies on Asthma in Childhood, Health Sciences, University of Copenhagen and Danish Pediatric Asthma Center, Copenhagen University Hospital, Gentofte, Denmark (TSA); the Department of Epidemiology and Biostatistics, School of Public Health, Imperial College, London, United Kingdom (DR); the Instituto de Investigación Sanitaria de Palma, Palma de Mallorca, Spain (DR); the Centro de Investigacíon Biomédica en Red Fisiopatologia de la Obesidad y Nutrición, Mallorca, Spain (DR); the Medical Research Council Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom (KSV, NJW, and RJFL); the Hugh Sinclair Unit of Human Nutrition, Department of Food and Nutritional Sciences, School of Chemistry, Food and Pharmacy, University of Reading, Reading, United Kingdom (KSV); the Section for Epidemiology, Department of Public Health, Aarhus University, Aarhus, Denmark (JNØ); the Cancer Research and Prevention Institute-Istituto per lo Studio e la Prevenzione Oncologica, Florence, Italy (BB and DP); the Center for Nutrition, Prevention and Health Services, National Institute for Public Health and the Environment Bilthoven, Netherlands (JMAB and DLvdA); the Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbruecke Arthur-Scheunert-Allee 114-116, Nuthetal, Germany (HB); and the Icahn School of Medicine at Mount Sinai, The Charles Bronfman Institute for Personalized Medicine, The Mindich Child Health and Development Institute, The Genetics of Obesity and Related Metabolic Traits Program, New York, NY - - 2014
Several studies have shown that adherence to the Mediterranean Diet measured by using the Mediterranean diet score (MDS) is associated with lower obesity risk. The newly proposed Nordic Diet could hold similar beneficial effects. Because of the increasing focus on the interaction between diet and genetic predisposition to adiposity, studies ...
García-Calzón Sonia S Department of Nutrition, Food Science and Physiology, University of Navarra, Pamplona, - - 2014
Oxidative stress and inflammation seem to be potential underlying mechanisms for telomere attrition. A lack of specific antioxidants is believed to increase free radical damage and a greater risk for telomere shortening. Our aim was to evaluate the relationship between diet and leukocyte telomere length in a cross-sectional study of ...
Tomiyama A Janet AJ Department of Psychology, University of California, Los - - 2014
Weight discrimination is associated with increased risk of obesity. The mechanism of this relationship is unknown, but being overweight is a highly stigmatized condition and may be a source of chronic stress that contributes to the development and pathophysiology of obesity. The objective of this study was to test whether ...
Vergès Bruno B Department of Endocrinology-Diabetology, University - - 2014
Context: Low plasma HDL cholesterol is a major abnormality in abdominal obesity. This relates due to accelerated HDL catabolism but the underlying mechanism requires further elucidation. The relationships between HDL catabolism and other variables that may be modified in abdominal obesity, such as VLDL subspecies (VLDL1, VLDL2) kinetics, liver fat ...
Yanai Hidekatsu H Department of Internal Medicine, National Center for Global Health and Medicine Kohnodai Hospital, Chiba, - - 2014
High-density lipoprotein (HDL) is a lipoprotein which has anti-atherogenic property by reverse cholesterol transport from the peripheral tissues to liver. Low HDL-cholesterol (HDL-C) levels are associated with the development of coronary artery diseases (CADs). Various epidemiological studies have suggested that the development of CAD increase in individuals with less than ...
Ooi Esther M EM The Department of Clinical Biochemistry, The Copenhagen General Population Study, Herlev Hospital, Herlev, Denmark & School of Medicine and Pharmacology, University of Western Australia, Perth, Western Australia, - - 2014
-Low plasma 25-hydroxyvitamin D [25(OH)D] levels are associated with high cardiovascular risk. This may be because low 25(OH)D levels are associated with high levels of atherogenic lipoproteins, but whether these two risk factors are genetically associated is unknown. We tested this hypothesis. -Using a Mendelian randomization approach, potential genetic associations ...
Olsson Erika E Department of Public Health and Caring Sciences, Clinical Nutrition and Metabolism, Uppsala University, Uppsala, - - 2014
Background: Adherence to dietary patterns has been associated with cognitive decline and dementia, but studies are inconsistent. Objective: Dietary patterns, i.e., WHO recommendations (Healthy Diet Indicator), a Mediterranean-like diet (modified Mediterranean Diet Score, mMDS), and a low carbohydrate high protein diet (LCHP), were related to incident cognitive dysfunction, as indicated ...
Hisamatsu Takashi T Center for Epidemiologic Research in Asia, Shiga University of Medical Science, Otsu, Japan; Department of Public Health, Shiga University of Medical Science, Otsu, Japan; Department of Cardiovascular and Respiratory Medicine, Shiga University of Medical Science, Otsu, Japan. Electronic address: - - 2014
The utility of lipoprotein particle profiles measured by nuclear magnetic resonance (NMR) spectroscopy beyond standard serum lipids remains inconclusive. Furthermore, few studies have compared NMR measurements with standard lipids in association with coronary artery calcification (CAC) in Japanese, where the coronary atherosclerotic burden is low. We examined whether NMR-based lipoprotein ...
Rogacev Kyrill S KS From the Department of Internal Medicine IV, Nephrology and Hypertension, Saarland University Medical Center, Homburg, Germany (K.S.R., A.M.Z., I.E., S.S., D.F., G.H.H.); Department of Internal Medicine III, Cardiology, Angiology and Intensive Care Medicine, Saarland University Medical Center, Homburg, Germany (K.S.R., M.B.); and Department of Medicine, Imperial College London, London, United Kingdom (K.J.W.). kyrill.rogacev@uks.eu - - 2014
Patients with chronic kidney disease (CKD) display impaired cholesterol efflux capacity and elevated CD14(++)CD16(+) monocyte counts. In mice, dysfunctional cholesterol efflux causes monocytosis. It is unknown whether cholesterol efflux capacity and monocyte subsets are associated with CKD. In 438 patients with CKD, mediators of cholesterol efflux capacity (high-density lipoprotein cholesterol/apolipoprotein ...
Connors Kimberly E KE Faculty of Kinesiology, University of Calgary, Calgary, Canada - - 2014
-Elevated levels of lipids and lipoproteins have strong genetic determinants, and are recognized as key risk factors for atherogenesis and cardiovascular disease (CVD), particularly in the postprandial state. Study aims were to determine if young adults, when stratified by genotype at the rs646776 variant of the 1p13 locus, displayed differential ...
Tan Paul P Centre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Montrèal, Quèbec, Canada; Department of Biochemistry and Molecular Medicine of the Université de Montréal, Montrèal, Quèbec, Canada; Montreal Diabetes Research Center, Montrèal, Quèbec, - - 2014
Obesity is a worldwide epidemic and current treatments have limited success thus, novel therapies are warranted. Our objective was to determine whether the prorenin/renin receptor [(P)RR] is implicated in obesity. Mice received a normal or high-fat/high-carbohydrate diet with the handle region peptide (HRP), a (P)RR blocker, or saline for 10 ...
Corella Dolores D From the Department of Preventive Medicine and Public Health, School of Medicine, University of Valencia, Valencia, Spain (DC, JVS, CO-A, OP, and EMA); CIBER Fisiopatología de la Obesidad y Nutrición, Instituto de Salud Carlos III, Madrid, Spain (DC, JVS, RE, OC, CO-A, OP, MÁM-G, MB, M Fitó, FA, JL, EMA, GTS, LS-M, CM-B, VR-G, M Fiol, EV, XP, and ER); Department of Internal Medicine, Hospital Clinic, IDIBAPS, Barcelona, Spain (RE); Department of Computer Languages and Systems, University Jaume I, Castellon, Spain (OC); Department of Preventive Medicine and Public Health, School of Medicine, University of Navarra, Pamplona, Spain (MÁM-G); Human Nutrition Unit, Faculty of Medicine, IISPV, University Rovira i Virgili, Reus, Spain (MB); Cardiovascular Epidemiology Unit, Municipal Institut for Medical Research, Barcelona, Spain (M Fitó); Department of Cardiology, Hospital Txagorritxu, Vitoria, Spain (FA); Department of Family Medicine, Primary Care Division of Sevilla, Sevilla, Spain (JL); Department of Biochemistry and Molecular Biology, Clinical Analysis Service-CDB, HGUV, University of Valencia, Valencia, Spain (GTS); Department of Clinical Sciences, University of Las Palmas de Gran Canaria, Las Palmas de Gran Canaria, Spain (LS-M); Department of Epidemiology, School of Medicine, University of Málaga, Málaga, Spain (CM-B); Instituto de la Grasa, Consejo Superior Investigaciones Cientificas, Seville (VR-G); University Institute for Health Sciences Investigation, Hospital Son Dureta, Palma de Mallorca, Spain (M Fiol); Primary Care Division, Catalan Institute of Health, Barcelona, Spain (EV); Lipids and Vascular Risk Unit, Internal Medicine, Hospital Universitario de Bellvitge, Hospitalet de Llobregat, Barcelona, Spain (XP); Nutrition and Genomics Laboratory, JM-USDA Human Nutrition Research Center on Aging at Tufts University, Boston, MA (KR, JMO); Lipid Clinic, Endocrinology and Nutrition Service, Institut d'Investigacions Biomèdiques August Pi Sunyer, Hospital Clinic, Barcelona, Spain (ER); IMDEA Alimentación, Madrid, Spain (JMO); and Department of Cardiovascular Epidemiology and Population Genetics, Centro Nacional de Investigaciones Cardiovasculares, Madrid, Spain - - 2014
MicroRNAs have emerged as important epigenetic regulators in cardiovascular diseases (CVDs). Using an observational meta-analysis design, we previously characterized a gain-of-function microRNA-410 target site polymorphism (rs13702T>C) in the 3'untranslated region of the lipoprotein lipase (LPL) gene. The C allele was associated with lower triglycerides, and this association was modulated by ...
Frankenfeld Cara L CL Department of Global and Community Health, George Mason University, Fairfax, VA - - 2014
The study objective was to evaluate independent and interactive associations of dietary fiber intake and high urinary enterolignans with cardiometabolic risk factors. The analysis included 2260 adults (≥20 y of age) from the 2003-2010 NHANES. Logistic regression models were used to evaluate obesity and clinically defined obesity and cardiometabolic risk ...
Bondia-Pons Isabel I VTT Technical Research Centre of Finland, Espoo, Finland; Department of Food Science and Physiology, Research Building, University of Navarra, Pamplona, - - 2014
Dysregulation of lipid homeostasis is related to multiple major healthcare problems. The aim of this study was to investigate the effects of n-3 fatty acid (FA) and polyphenol rich diets on plasma and HDL fraction lipidomic profiles in subjects at high cardiovascular risk. Ultra performance LC coupled to quadrupole TOF/MS ...
Tellis Constantinos C - - 2014
Lipoprotein-associated phospholipase A2 (Lp-PLA2), also named as platelet-activating factor (PAF)-acetylhydrolase, exhibits a Ca2+-independent phospholipase A2 activity and catalyzes the hydrolysis of the ester bond at the sn-2 position of PAF and oxidized phospholipids (oxPL). These phospholipids are formed under oxidative and inflammatory conditions, and may play important roles in atherogenesis. ...
Ma Jiantao J Nutrition Epidemiology - - 2014
Abdominal adiposity, particularly visceral adipose tissue (VAT), is independently linked to the pathogenesis of diabetes and cardiovascular diseases. Emerging evidence suggests that greater intake of sugar-sweetened beverages (SSBs) may be associated with abnormal fat accumulation in VAT. We examined whether habitual SSB consumption and diet soda intakes are differentially associated ...
Browne Richard W RW Department of Biotechnical and Clinical Laboratory Sciences, State University of New York, Buffalo, NY, - - 2014
High serum cholesterol is adversely associated with clinical and imaging disease progression outcomes in multiple sclerosis (MS) and in clinically isolated syndrome (CIS), the earliest stage of MS. Low vitamin D levels are associated with an increased risk of disease progression. To investigate the mechanisms mediating the adverse effects of ...
Fu Xiaohua X Department of Reproductive Endocrinology, Zhejiang Provincial People's Hospital, Hangzhou, PR - - 2014
Objective: To investigate the association of central fat with metabolic risks in normal BMI Chinese people. Methods: Normal BMI subjects (18.5 ≤ BMI < 24, n = 520) aged 18-82 years were included. Blood pressure, triglycerides, high-density lipoprotein cholesterol and fasting plasma glucose were collected as metabolic risk factors. Dual-energy ...
Smagris Eriks E Departments of Molecular Genetics and Internal Medicine, University of Texas Southwestern Medical Center, Dallas, - - 2014
A sequence polymorphism (rs738409, I148M) in patatin-like phospholipid domain containing protein 3 (PNPLA3), is strongly associated with nonalcoholic fatty liver disease (NAFLD), but the mechanistic basis for this association remains enigmatic. Neither ablation nor overexpression of wild-type PNPLA3 affects liver fat content in mice, whereas hepatic overexpression of the human ...
Glintborg Dorte D Department of Endocrinology and Metabolism, Odense University Hospital, Kløvervænget 6, 3rd floor, 5000, Odense C, Denmark, - - 2014
Central obesity in polycystic ovary syndrome (PCOS) is associated with increased inflammatory markers and increased risk for type 2 diabetes. To evaluate if improved body composition during treatment with metformin (M) vs. oral contraceptive pills (OCP) was associated with changes in circulating adiponectin, interleukin (IL)-6, and monocyte chemoattractant protein (MCP)-1. ...
Jackson Chandra L CL From the Department of Nutrition, Harvard School of Public Health, Boston, - - 2014
There is some concern that the high-fat, energy-dense content of nuts may promote weight gain. Nuts, however, are rich in protein and dietary fiber, which are associated with increased satiety. They also contain high amounts of vitamins, minerals, antioxidants, and phytoesterols that may confer health benefits for cardiovascular disease and ...
Bailón-Soto Claudia E CE Centro Interdisciplinario de Investigación para el Desarrollo Integral Regional del IPN Unidad Durango, CIIDIR-IPN, Durango, - - 2014
High triglyceride levels are closely related to cardiovascular disease. Its development lays on age, diet, physical activity, ethnicity and genetic factors. Among the last, the CYP1A1*2C allele has an influence on the metabolism of cholesterol and other fatty acids. We undertook this study to determine the frequency of CYP1A1*2C and ...
Warstadt Nicholus M NM Imaging Genetics Center, Institute for Neuroimaging and Informatics, Keck School of Medicine of the University of Southern California, Los Angeles, CA, - - 2014
Several common genetic variants influence cholesterol levels, which play a key role in overall health. Myelin synthesis and maintenance are highly sensitive to cholesterol concentrations, and abnormal cholesterol levels increase the risk for various brain diseases, including Alzheimer's disease. We report significant associations between higher serum cholesterol (CHOL) and high-density ...
Diffenderfer Margaret R MR Cardiovascular Nutrition Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, Massachusetts, - - 2014
Decreased size and increased density of LDL have been associated with increased coronary heart disease (CHD) risk. Elevated plasma concentrations of small dense LDL (sdLDL) correlate with high plasma triglycerides and low HDL cholesterol levels. This review highlights recent findings about the metabolism and composition of LDL subfractions. The development ...
Ahmadzadeh Alireza A Department of Molecular Medicine, Faculty of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, - - 2014
Atherosclerosis is the main cause of death in the world through causing ischemic heart disease (IHD). Altered serum lipid level is the most important risk factor for coronary artery disease (CAD). Many studies reveal a strong inverse association between low levels of high density lipoprotein cholesterol (HDL-C) and increased risk ...
Urban Lorien E LE Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, Massachusetts, - - 2014
To examine the relationship between dietary characteristics of self-selected foods and energy balance in a cafeteria-style dining hall. Ad libitum dietary intake from a self-selection menu was measured over two days in 151 adults (70% female, mean age 41 years, mean BMI 24.9 kg/m(2) ). The associations of dietary variables ...
Mora Samia S Divisions of Preventive Medicine & Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA - - 2014
-Low-density-lipoprotein (LDL) cholesterol is a strong risk factor for atherosclerosis but has an inverse association with AF. We aimed to provide insight into the paradoxical association of LDL-cholesterol with atrial fibrillation (AF) by evaluating the relationship of various lipoprotein measures and incident AF. -We prospectively evaluated lipoprotein measures among 23,738 ...
Sadeghi Masoumeh M Cardiac Rehabilitation Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, 8187698191, - - 2014
It is expected that dairy products such as cheeses, which are the main source of cholesterol and saturated fat, may lead to the development or increase the risk of cardiovascular and metabolic diseases; however, the results of different studies are inconsistent. This study was conducted to assess the association between ...
Tettey Prudence P Menzies Research Institute Tasmania, University of Tasmania, Hobart, - - 2014
There is accumulating data suggesting an association between serum lipids, apolipoproteins and disability in multiple sclerosis (MS). To investigate the associations between serum lipids, apolipoproteins and disability in MS. A cohort of 178 participants with clinically-definite MS in southern Tasmania, Australia were prospectively followed from 2002 - 2005, and serum ...
Chan D C DC Metabolic Research Centre, School of Medicine and Pharmacology, University of Western Australia, Perth, - - 2014
Ectopic deposition of fat in skeletal muscle is a feature of metabolic syndrome, but its specific association with very-low-lipoprotein (VLDL)-apolipoprotein (apo) B-100 metabolism remains unclear. We examined the association between skeletal muscle fat content and VLDL-apoB-100 kinetics in 25 obese subjects, and the responses of these variables to weight loss. ...
Zhang Jun J Department of Orthopedics, Zhejiang Provincial People's Hospital, Hangzhou, Zhejiang, - - 2014
The purpose of the study was to investigate the associations of fat mass (FM) and fat distribution with bone mineral density (BMD) in Chinese obese population. Three hundred and forty-seven Chinese obese females and 339 males aged 20-39 years were analyzed. Lean mass (LM), FM, percent body fat (%BF), android FM, ...
Grosso Giuseppe G Department of G.F. Ingrassia, Section of Hygiene and Public Health, University of - - 2014
Background: Intake of caffeinated beverages, such as coffee and tea, has been related to improvements in components of metabolic syndrome (MetS), but studies conducted in the Mediterranean region are scarce. The aim of this study was to evaluate whether or not consumption of a variety of beverages containing caffeine was ...
Vallianou Natalia G NG aPolykliniki General Hospital, Athens bDepartment of Nutrition and Dietetics, Harokopio University of Athens, - - 2014
Although butyrylcholinesterase is widely distributed in different tissues of the human body, its physiological role has not yet been defined. This study aimed to explore the relationship between butyrylcholinesterase and lipids levels, among apparently healthy adults. During 2009, 490 volunteers (46 ± 16 years, 40% men) who visited the outpatients' office of ...
Franca-Neto Antonio H AH Universidade Federal de Campina Grande, Campina Grande, PB, - - 2014
Because of the overweight epidemy, we would like to verify if maternal factors are associated with visceral and subcutaneous adiposity in newborns and check if the relationship between these factors could be proved. A cross-sectional study with 116 pairs of mothers and newborns was performed between November 2009 and November ...
Li Bin B Department of Medical Statistics and Epidemiology, School of Public Health, Sun Yat-sen University, Guangzhou, People's Republic of - - 2014
Some studies have investigated the association between folate intake and breast cancer prognosis, but the results have been far from conclusive. Thus, a meta-analysis was carried out to explore this association. We performed a comprehensive search of the PubMed, Web of Knowledge, and Cochrane databases from inception to May 2013. ...
Väistö Juuso - - 2014
Lower levels of physical activity (PA) and sedentary behaviour (SB) have been associated with increased cardiometabolic risk among children. However, little is known about the independent and combined associations of PA and SB as well as different types of these behaviours with cardiometabolic risk in children. We therefore investigated these ...
Nicklas Theresa A - - 2014
The relationship of snacking patterns on nutrient intake and cardiovascular risk factors (CVRF) in adults is unknown. The aim of this study was to examine the associations of snacking patterns with nutrient intake, diet quality, and a selection of CVRF in adults participating in the 2001-2008 National Health and Nutrition ...
Gilboa Suzanne M SM Division of Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, - - 2014
BACKGROUND In a recent study, high maternal periconceptional intake of vitamin E was found to be associated with risk of congenital heart defects (CHDs). To explore this association further, we investigated the association between total daily vitamin E intake and selected birth defects. We analyzed data from 4525 controls and ...
Wong Jyh Eiin JE Departments of Human Nutrition - - 2014
Adoption of optimal dietary habits during adolescence is associated with better health outcomes later in life. However, the associations between a pattern of healthy dietary habits encapsulated in an index and sociodemographic and nutrient intake have not been examined among adolescents. This study aimed to develop a behavior-based diet index ...
Wang Ying Y Department of Nutritional Sciences, University of Connecticut, Storrs, - - 2014
Hyperlipidemia and elevated circulating C-reactive protein (CRP) and total homocysteine (tHcy) concentrations are cardiovascular disease (CVD) risk factors. Previous studies indicated that higher serum carotenoid concentrations were inversely associated with some of these biomarkers. However, whether or not dietary carotenoid intake is inversely associated with these CVD risk biomarkers is ...
Golubic R R Medical Research Council Epidemiology Unit, University of Cambridge School of Clinical Medicine Box 285 Institute of Metabolic Science, Cambridge Biomedical Campus - - 2014
ObjectiveTo examine the independent associations of time spent in moderate-to-vigorous physical activity (MVPA) and sedentary (SED-time), with total and abdominal body fat (BF), and the bidirectionality of these associations in adults at high risk of type 2 diabetes.Design and subjectsWe measured MVPA (min/day) and SED-time (h/day) by accelerometry, and indices ...
Delvaux Immle I Department of Public Health, Ghent University, UZ 2 Blok A, De Pintelaan 185, 9000 Ghent, - - 2014
The study aim was to investigate the association between prenatal exposure to endocrine disrupting chemicals (EDCs) and the body composition of 7 to 9 year old Flemish children. The subjects were 114 Flemish children (50% boys) that took part in the first Flemish Environment and Health Study (2002-2006). Cadmium, PCBs, ...
Gray Belinda B Children's Nutrition Research Centre, Queensland Children's Medical Research Institute, The University of Queensland, Royal Children's Hospital, Herston, QLD, Australia; Centre for Integrative Clinical and Molecular Medicine, School of Medicine, The University of Queensland, Princess Alexandra Hospital, Woolloongabba, QLD, Australia; School of Medicine, The University of Queensland, Herston, QLD, - - 2014
Dysregulation of adipose hormones in obesity has been associated with the hastened development of metabolic syndrome and associated chronic disease sequalae including cardiovascular disease and type 2 diabetes mellitus. This study aims to identify common biochemical and anthropometric markers that impact adipose hormones, including adiponectin and leptin. Based on previous ...
Chróinín Danielle Ní DN From the Neurovascular Unit for Translational and Therapeutics Research (D. Ní C., M.M., L.A., Á.M., E.F., G.H., S.M., K. O'Rourke, P.J.K.) and the Departments of Vascular Surgery (K. O'Malley, M. O'Donohoe, C.M.) and Radiology (E.K., M. O'Connell), Mater University Hospital/University College Dublin; Connolly Hospital (E.D.); and St Vincent's University Hospital (I.N., M.B., M.C.), Dublin, - - 2014
We hypothesized that serum lipids, which experimental data suggest may be key initiators of carotid plaque inflammation, would be associated with plaque inflammation on (18)fluorodeoxyglucose (FDG)-PET in patients with acutely symptomatic carotid stenosis. In this cohort study, consecutive patients with acute symptomatic internal carotid artery (ICA) stenosis (≥50%) underwent carotid ...
Sheedfar Fareeba F University of Groningen, University Medical Center Groningen, Molecular Genetics, Groningen, The - - 2014
CD36 has been associated with obesity and diabetes in human liver diseases, however, its role in age-associated nonalcoholic fatty liver disease (NAFLD) is unknown. Therefore, liver biopsies were collected from individuals with histologically normal livers (n=30), and from patients diagnosed with simple steatosis (NAS; n=26). Patients were divided into two ...
Sieri Sabina S Affiliations of authors: Epidemiology and Prevention Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy (SS, CA, VP, FB, SG, VK); Medical Statistics Unit, Second University of Naples, Naples, Italy (PC); Hellenic Health Foundation, Athens, Greece (ATr); Department of Hygiene, Epidemiology and Medical Statistics, University of Athens Medical School, Athens, Greece (VB, EV); Escuela Andaluza de Salud Pública, Granada, Spain (M-JS); CIBER de Epidemiología y Salud Pública, Madrid, Spain (M-JS, M-DC, PA, EA); Instituto de Investigación Biosanitaria de Granada, Granada, Spain (M-JS); Department of Epidemiology, Murcia Health Authority, Murcia, Spain (M-DC); Public Health Division of Gipuzkoa, BioDonostia Research Institute, Health Department of Basque Region, San Sebastian, Spain (PA); Health Information Unit, Public Health and Health Planning Directorate, Asturias, Spain (JRQ); Navarre Public Health Institute, Pamplona, Spain (EA); Unit of Nutrition, Environment and Cancer, Cancer Epidemiology Research Program, Catalan Institute of Oncology, Barcelona, Spain (GB); Molecular and Nutritional Epidemiology Unit, ISPO-Cancer Research and Prevention Institute, Florence, Italy (GM); Department of Clinical and Experimental Medicine, University of Naples Federico II, Naples, Italy (SP); Center for Cancer Prevention, Turin, Italy (CS); Human Genetics Foundation, Turin, Italy (CS); Department of Oncology, Histopathology Unit (RT), and Cancer Registry (RT), Ospedale Civile "M.P. Arezzo," Ragusa, Italy; INSERM, Centre for Research in Epidemiology and Population Health, U1018, Nutrition, Hormones and Women's Health team, F-94805, Villejuif, France (MC-BR); Univ Paris Sud, UMRS 1018, F-94805, Villejuif, France (FC-C); IGR, F-94805, Villejuif, France (GF); Department of Epidemiology, Julius Center for Health Sciences and Primary Care (PHMP, CHvG), and Department of Gastroenterology and Hepatology (HBB-d-M), University Medical Center Utrecht, Utrecht, the - - 2014
We prospectively evaluated fat intake as predictor of developing breast cancer (BC) subtypes defined by estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor 2 receptor (HER2), in a large (n = 337327) heterogeneous cohort of women, with 10062 BC case patients after 11.5 years, estimating BC hazard ...
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