Search Results
Results 1 - 50 of 1315
1 2 3 4 5 6 7 8 9 10 >
Papoutsoglou Sofronios E SE Faculty of Animal Science and Aquaculture, Agricultural University of Athens, Athens, Greece, - - 2014
This study presents the results of the response of Sparus aurata to three different musical stimuli, derived from the transmission (4 h per day, 5 days per week) of particular music pieces by Mozart, Romanza and Bach (140 dBrms re 1 μPa), compared to the same transmission level of white noise, while the underwater ...
Sam Amir H AH Section of Investigative Medicine, Division of Diabetes, Endocrinology and Metabolism, Imperial College London, - - 2014
Context and objective: No current biomarker can reliably predict visceral and liver fat content, both of which are risk factors for cardiovascular disease. Vagal tone has been suggested to influence regional fat deposition. Pancreatic polypeptide (PP) is secreted from the endocrine pancreas under vagal control. We investigated the utility of ...
Watanabe Genya G Graduate School of Science and Technology, Niigata University, Niigata, - - 2014
Regulation of taste is important for improving meat quality and glutamate (Glu) is one of the important taste-active components in meat. Here, the effects of dietary lysine (Lys) content on taste-active components in meat, especially free Glu, were investigated. Fourteen-day-old broiler chicks (Gallus gallus) were fed on diets containing 100% ...
Loomba Rohit R NAFLD Translational Research Unit, La Jolla, CA; Division of Gastroenterology, Department of Medicine, La Jolla, CA; Division of Epidemiology, Department of Family and Preventive Medicine, La Jolla, - - 2014
Ezetimibe inhibits intestinal cholesterol absorption and lowers low-density-lipoprotein (LDL) cholesterol. Uncontrolled studies have suggested that it reduces liver fat as estimated by ultrasound in nonalcoholic steatohepatitis (NASH). Therefore, we aimed to examine the efficacy of ezetimibe versus (vs.) placebo in reducing liver fat by magnetic-resonance-imaging derived proton-density-fat-fraction (MRI-PDFF) and liver ...
Kowalski Greg M GM Centre for Physical Activity and Nutrition Research, School of Exercise and Nutrition Sciences, Deakin University, Burwood Victoria 3125, Australia; Biology of Lipid Metabolism Laboratory, Department of Physiology, Monash University, School of Biomedical Sciences, Clayton Victoria 3800, Australia. Electronic address: - - 2014
Hepatic insulin resistance is a major risk factor for the development of type 2 diabetes and is associated with the accumulation of lipids, including diacylglycerol (DAG), triacylglycerols (TAG) and ceramide. There is evidence that enzymes involved in ceramide or sphingolipid metabolism may have a role in regulating concentrations of glycerolipids ...
Guo Lina - - 2014
The aim of present study is to investigate the hypocholesterolemic effects of the oat components other than the beta-glucan in rats fed with a hypercholesterolemic diet. Four-week-old male Wister rats were divided into 6 groups of 7 rats each with similar mean body weights and serum cholesterol concentrations. Rats were ...
Mu Xiyan X College of Sciences, China Agricultural University, Beijing, People's Republic of - - 2014
Difenoconazole is a widely used triazole fungicide, its extensive application may potentially cause toxic effects on non-target organisms. To investigate the effect of difenoconazole on cholesterol content and related mechanism, adult zebrafish were exposed to environmental related dosage (0.1, 10 and 500 μg/L) difenoconazole. The body weight and hepatic total cholesterol ...
Hoogenboom Ron L A P RL RIKILT Wageningen UR, Akkermaalsbos 2, Wageningen, The Netherlands. Electronic address: - - 2014
A major part of sheep livers contains levels of polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs) and polychlorinated biphenyls (PCBs) above the former but to some extent also the new maximum levels (MLs) in the EU. In order to investigate the relationship between the intake of these contaminants and their accumulation in ...
Chung Min-Yu MY 1 Department of Nutritional Sciences, University of Connecticut , Storrs, Connecticut, USA - - 2014
Abstract Green tea extract (GTE) protects against nonalcoholic steatohepatitis (NASH) by decreasing hepatic steatosis and nuclear factor kappa B (NFκB) activation. We hypothesized that hypolipidemic and anti-inflammatory activities of GTE would protect against NASH by reducing cyclooxygenase-2 (COX-2), an NFκB-dependent enzyme, and prostaglandin E2 (PGE2) in a dietary fat-induced obese ...
Park Yongsoon Y Department of Food and Nutrition, Hanyang University, Wangsimni-ro 222, Seongdong-gu, Seoul 133-791, - - 2014
The purpose of the current study was to investigate the effect of red pericarp glutinous rice rich in polyphenols (Jakwangchalbyeo, red rice) on serum and hepatic levels of cholesterol and hepatic protein expression linked to synthesis and degradation of cholesterol in a hypercholesterolemic mice diet as compared with brown rice. ...
Zhu Xueping X *Department of Neonatology †Institute of Pediatric Research ‡Department of Neonatology Surgery, Children's Hospital Affiliated to Soochow University, Suzhou, Jiangsu, - - 2014
Parenteral nutrition in infants with gastrointestinal disorders can be lifesaving, but it is also associated with parenteral nutrition-associated liver disease. We investigated the effects of incorporating ω-3 fish oil in a parenteral nutrition mixture on signs of parenteral nutrition-associated liver disease and explored the mechanism involved in this process. Seven-day-old ...
Miller Colette N CN Department of Foods and Nutrition, Edgar L. Rhodes Center for Animal and Dairy Science, University of Georgia, Athens, Georgia, - - 2014
Menopausal reduction in estrogen causes increased adipose accumulation, leading many to turn to dietary supplements to prevent and treat such changes. Enhanced adipose mobilization stimulated by some supplements can increase the risk of non-alcoholic fatty liver disease (NAFLD). Cytoprotective and anti-obesity compounds may prevent the lipotoxicity associated with mobilization. A ...
Jones Ryan D RD Department of Physiology, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX, United States. Electronic address: - - 2014
Mice deficient in cholesterol 7α-hydroxylase (Cyp7a1) have a diminished bile acid pool (BAP) and therefore represent a useful model for investigating the metabolic effects of restoring the pool with a specific BA. Previously we carried out such studies in Cyp7a1(-/-) mice fed physiological levels of cholic acid (CA) and achieved ...
Dannenberger Dirk - - 2014
The study assessed the effects of reduced protein (RPD) vs high protein diet (HPD) in combination with n-3/n-6 PUFA-containing plant oils [linseed oil (LO) /sunflower seed oil (SO)] supplementation on lipid metabolism-related protein expression and fatty acid concentrations in porcine tissues. Forty male Landrace pigs (castrates) were allocated into four ...
Vlachová M M Institute for Clinical and Experimental Medicine, Prague, Czech Republic. - - 2014
To understand the pathogenesis of hypercholesterolemia in Prague hereditary hypercholesterolemic (PHHC) rat, we analyzed the response of hepatic transcriptome to dietary cholesterol in PHHC and control Wistar rats. Male PHHC and Wistar rats were fed chow (C), 5 % fat (palm kernel oil) (CF) or 1 % cholesterol + 5 ...
Yang Jing J Department of Endocrinology and Metabolism, The First Affiliated Hospital, China Medical University, Shenyang, 110001, - - 2014
The purpose of this study was to investigate whether the glucagon-like peptide-1 (GLP-1) analog liraglutide can alleviate endoplasmic reticulum (ER) stress and insulin resistance (IR) in the liver of high-fat diet-induced insulin-resistant rats. Eighty-five male Sprague-Dawley rats were fed with normal chow or a high-fat diet for 12 weeks. The IR ...
Jia Yaoyao Y Department of Biotechnology, Graduate School of Biotechnology, Korea University, Seoul, 136-713, Republic of - - 2014
This study investigated metabolic effects of ursolic acid (UA), the peroxisome proliferation-activated receptor (PPAR)-α activator, in vivo. High-fat diet (HFD)-fed C57BL/6J mice were orally administered UA (50 or 200 mg/kg body weight) for 8 weeks. UA reduced liver and adipose tissue mass, adipocyte size, and plasma leptin concentrations, plasma triglyceride ...
Amlund Heidi H National Institute of Nutrition and Seafood Research (NIFES), P.O. Box 2029 Nordnes, 5817 Bergen, Norway. Electronic address: - - 2014
Methylmercury (MeHg) is a toxicant of concern for aquatic food chains. In the present study, the assimilation and depuration of dietary MeHg and the influence of dietary selenium on MeHg toxicokinetics was characterised in zebrafish (Danio rerio). In a triplicate tank experimental design (n=3 tanks per treatment group), adult zebrafish ...
Langhi Cédric C Edward A. Doisy Department of Biochemistry & Molecular Biology, Center for Cardiovascular Researchm Saint Louis University, Saint Louis, MO, - - 2014
The cell death-inducing DFFA-like effector c (CIDEC; also known in rodents as FSP27 or fat-specific protein 27) is a lipid droplet-associated protein that promotes intracellular triglyceride storage. CIDEC/Fsp27 is highly expressed in adipose tissue but undetectable in normal liver. Its hepatic expression, however, rises during fasting or under genetic or ...
Mialon M M MM INRA, UMR1213 Herbivores, F-63122 Saint-Genès-Champanelle, France Clermont Université, VetAgro Sup, UMR1213 Herbivores, BP 10448, F-63000, Clermont-Ferrand, France - - 2014
The aim of this study was to compare the responses in fattening performance and meat composition to high-concentrate diets rich in either starch and lipids (especially omega-3 fatty acids) or fibrous by-products. A total of 140 Charolais bulls (initially 319 ± 27 kg BW) were allocated to 3 high-concentrate diets ...
Duan Xiao-Yan - - 2014
BackgroundNonalcoholic fatty liver disease (NAFLD) is a risk for hepatocellular carcinoma (HCC), but the association between a high-fat diet (HFD) and HCC is not fully understood. In this study, we investigated whether a high-saturate-fat diet affects hepatocarcinogenesis induced by administration of diethylnitrosamine (DEN).MethodsAdult SD rats were randomized into the following ...
Kruse Michael M Department of Clinical Nutrition, German Institute of Human Nutrition Potsdam-Rehbruecke, Germany; Department of Endocrinology, Diabetes and Nutrition, Charité University Medicine Berlin, - - 2014
Obesity is associated with hyperlipidemia, hepatic steatosis and low-grade inflammation. Studies have shown that MUFA as well as PUFA have beneficial effects on blood lipids and the inflammatory state. This study investigates a daily supplementation of either 50 g of rapeseed/canola (RA) or olive (OL) oil over four weeks on ...
Hauser-Davis Rachel Ann RA Pontifícia Universidade Católica - Rio de Janeiro (PUC-Rio), Chemistry Department, Rua Marquês de São Vicente, 225, Gávea, CEP 22453-900, Rio de Janeiro, RJ, Brazil; Universidade Federal do Estado do Rio de Janeiro - UNIRIO, Av. Pasteur, 458 - Urca, CEP 22290-240, Rio de Janeiro, RJ, Brazil. Electronic address: - - 2014
Microcystin (MC) accumulation and depuration in environmentally exposed tilapia (Oreochromis niloticus) at a chronically contaminated eutrophic lagoon was studied. This is one of the scarce reports on microcystin accumulation in bile of environmentally exposed fish, and gonad MC accumulation in the field, in contrast to laboratory exposure experiments. Results show ...
Ma Y L YL Department of Animal and Food Sciences, University of Kentucky, Lexington 40546 - - 2014
The objective of this experiment was to evaluate two supplemental forms of Se on reproductive performance and tissue trace mineral concentration in fetus and first-parity gilts during pregnancy and their progeny. Crossbred gilts (n = 100) were selected at 183 ± 2.7 d and 137 ± 10 kg BW and ...
Wang Guo-Xiao GX Life Sciences Institute and Department of Cell &Developmental Biology, University of Michigan Medical Center, Ann Arbor, Michigan, - - 2014
Brown fat activates uncoupled respiration in response to cold temperature and contributes to systemic metabolic homeostasis. To date, the metabolic action of brown fat has been primarily attributed to its role in fuel oxidation and uncoupling protein 1 (UCP1)-mediated thermogenesis. Whether brown fat engages other tissues through secreted factors remains ...
Almaida-Pagán P F PF School of Natural Sciences, Institute of Aquaculture, University of Stirling, Stirling, FK9 4LA, Scotland, UK, - - 2014
Mitochondria are among the first responders to various stressors that challenge the homeostasis of cells and organisms. Mitochondrial decay is generally associated with impairment in the organelle bioenergetics function and increased oxidative stress, and it appears that deterioration of mitochondrial inner membrane phospholipids (PL), particularly cardiolipin (CL), and accumulation of ...
Alférez María Jm MJ Department of Physiology, Faculty of Pharmacy,University of Granada and Institute of Nutrition and Food Technology,Granada - - 2014
The aim of the current study was to asses the effect of goat or cow milk-based diets, either normal or Fe-overloaded and folic acid supplement on some aspects of hepatic physiology, enzymatic antioxidant defence and lipid peroxidation in liver, brain and erythrocyte of control and anaemic rats after chronic Fe ...
Heying Emily - - 2014
The xanthophyll β-cryptoxanthin provides vitamin A and has other purported health benefits. Laying hens deposit xanthophyll carotenoids into egg yolk. Hens (n = 8/group) were fed conventional-bred high β-cryptoxanthin biofortified (orange) maize, tangerine peel-fortified white maize, lutein-fortified yellow maize, or white maize for 40 d to investigate yolk color changes ...
Zhang Tianshun T Department of Agrobioscience, Graduate School of Agricultural Science, Kobe University, Kobe 657-8501, Japan. - - 2014
Two main chalcones, 4-hydroxyderricin and xanthoangelol, from Ashitaba, which is a food ingredient and a folk medicine in Asia, have been demonstrated to modulate lipid metabolism in 3T3-L1 and HepG2 cells. In this study, we investigated the effects of Ashitaba extract on adiposity in mice fed a high-fat (HF) diet ...
Go Ryeo-Eun RE 1 Laboratory of Biochemistry and Immunology, College of Veterinary Medicine, Chungbuk National University , Cheongju, - - 2014
Abstract Palm oil is a common cooking ingredient used in the commercial food industry as the second largest consumed vegetable oil in the world. Because of its lower cost and highly saturated nature, it usually maintains a solid form at room temperature and is used as a cheap substitute for ...
Caimari Antoni A Grup de Recerca en Nutrició i Salut (GRNS). Centre Tecnològic de Nutrició i Salut (CTNS), TECNIO, CEICS, Avinguda Universitat, 1, 43204, Reus, Spain, - - 2015
We previously demonstrated that hamsters that were fed either a standard diet (STD) or a high-fat diet (HFD) and treated with a grape seed procyanidin extract (GSPE) showed decreased adiposity and circulating levels of free fatty acids compared with hamsters treated with a vehicle (Caimari et al. in Int J ...
Henson Joseph J 1NIHR Leicester-Loughborough Diet, Lifestyle and Physical Activity Biomedical Research Unit, UK and Diabetes Research Centre, College of Medicine, Biological Sciences and Psychology, University of Leicester, United Kingdom; 2Department of Cancer Studies and Molecular Medicine, College of Medicine, Biological Sciences and Psychology, University of Leicester, United Kingdom; 3Department of Cardiovascular Sciences, College of Medicine, Biological Sciences and Psychology, University of Leicester, United Kingdom; 4NIHR Leicester-Loughborough Diet, Lifestyle and Physical Activity Biomedical Research Unit, UK and School of Sport, Exercise and Health Sciences, Loughborough University, United Kingdom; 5School of Sport, University of Stirling, United Kingdom; 6Department of Cardiovascular Sciences, University of Leicester and the NIHR Leicester Cardiovascular Biomedical Research Unit, Leicester, United Kingdom; 7NIHR Collaborations for Leadership in Applied Health Research and Care (CLAHRC) East Midlands, UK and Diabetes Research Centre, College of Medicine, Biological Sciences and Psychology, University of Leicester, United - - 2014
The effect of sedentary behaviour on regional fat deposition, independent of physical activity remains equivocal. We examined the cross-sectional associations between objectively measured sedentary time and markers of regional fat distribution (heart, liver, visceral, subcutaneous and total body fat) in a population at a high risk of type 2 diabetes ...
Do Hyun Ju HJ Department of Food and Nutrition, Korea University, Seoul 136-704, Republic of - - 2014
The aim of this study was to determine whether 1-deoxynojirimycin (DNJ) isolated from Bacillus subtilis MORI beneficially influences lipid metabolism and mitochondrial function in the liver of mice fed a high-fat diet in addition to the anti-obesity properties of DNJ. Male C57BL/6 mice (n = 29; 5 weeks old) were randomly assigned ...
Petzold M M 1Institute of Animal Nutrition,Friedrich-Loeffler-Institute (FLI),Federal Research Institute for Animal Health,38116 - - 2014
The study aimed to examine effects of supplemented CLA to periparturient dairy cows receiving different concentrate proportions antepartum (a.p.) to investigate CLA effects on metabolism and immune function. Compared with adapted feeding, high-concentrate diet a.p. should induce a ketogenic metabolic situation postpartum (p.p.) to better understand how CLA works. A ...
Lim Seon Hee SH Department of Internal Medicine, Healthcare Research Institute, Seoul National University Hospital Healthcare System Gangnam Center, Seoul, South - - 2014
Gallbladder polyps (GBPs) appear to be strongly associated with obesity and metabolic disease. To date, the relationship between GBPs and fatty liver has not been adequately evaluated. The aim of the present study was to investigate whether GBPs are associated with fatty liver, which is an ectopic regional fat deposit, ...
Murugesan G Raj GR Department of Animal Science, Iowa State University, Ames, IA, 50011, USA; Currently with BIOMIN America Inc., San Antonio, TX, 78213, - - 2014
Efficacy of a multi-strain direct-fed microbial product (PoultryStar® ME; PS) and a xylanase enzyme product on the dietary energy utilization efficiency and resulting performance in broiler chickens was evaluated. Apart from performance parameters, cecal, and serum metabolites and activities of hepatic enzymes involved in energy metabolism were also determined. Ross ...
Bi Xiuli X College of Life Science, Liaoning University, Shenyang, 110036, People's Republic of China. - - 2014
The aim of this study was to investigate the effects of Callistephus chinensis flower (CCF) polyphones on symptoms of metabolic syndrome in a newly developed high-fat diet-induced non-alcoholic fatty liver disease (NAFLD) mouse model. C57BL/6J mice were fed a high fat diet (HFD; 50% energy as fat) with normal drinking ...
Weekley Claire M CM School of Chemistry and Physics, The University of Adelaide, SA 5005, Australia. - - 2014
The biological activity of selenium is dependent on its chemical form. Therefore, knowledge of Se chemistry in vivo is required for efficacious use of selenium compounds in disease prevention and treatment. Using X-ray absorption spectroscopy, Se speciation in the kidney, liver, heart, spleen, testis and red blood cells of rats ...
Quintero-Platt Geraldine G Servicio de Medicina Interna, Hospital Universitario de Canarias, Universidad de La Laguna, Tenerife, Canary Islands, - - 2014
To analyze the relationship between low vitamin D levels and mortality among alcoholics. One hundred twenty-eight alcoholic patients admitted to our hospital were followed up as outpatients. Nutritional status was evaluated measuring percentages of fat and lean mass in different body compartments. Lower vitamin D levels were observed in patients ...
Lu T T Department of Animal and Poultry Sciences, Virginia Tech, Blacksburg, VA - - 2014
The objective of the study was to determine the effects of a dietary antioxidant blend (AOX, ethoxyquin and propyl gallate) and vitamin E on growth performance, liver function, and oxidative status in pigs fed diets high in oxidants. Crossbred barrows (n = 100, 10.91 ± 0.65 kg BW, 36 ± ...
Dong Gui-Fang GF Hubei Key Laboratory of Animal Nutrition and Feed Science, Wuhan, 430023, Hubei, China, - - 2014
Fatty liver syndrome is a prevalent problem of farmed fish. Conjugated linoleic acid (CLA) has received increased attention recently as a fat-reducing fatty acid to control fat deposition in mammals. Therefore, the aim of the present study was to determine whether dietary CLA can reduce tissue lipid content of darkbarbel ...
Hassanin Amal A Department of Clinical Pharmacology, Faculty of Medicine, Mansoura University, Mansoura 35516, - - 2014
Nonalcoholic fatty liver disease (NAFLD) is considered to be a hepatic manifestation of metabolic syndrome, and has been etiologically associated with insulin resistance (IR). The histopathology of NAFLD ranges between simple steatosis and nonalcoholic steatohepatitis (NASH), with or without fibrosis. The aim of the present study was to examine the ...
Prévéraud D P DP Adisseo France S.A.S., Center of Expertise and Research in Nutrition, 6 route Noire, 03600 Commentry, France INSERM, UMR1062, "Nutrition, Obesity and Risk of Thrombosis," 13385 Marseille, France INRA, UMR1260, 13385 Marseille, France Aix-Marseille University, Faculté de Médecine, 13385 Marseille, France - - 2014
A study was performed in growing pigs to evaluate the efficacy of α-tocopherol (Tol) concentration in plasma, muscle, liver, and adipose tissue following dietary supplementation with vitamin E (VE) and various sources of fat. The trial involved 96 piglets weaned at an average of 28 d of age. Piglets were ...
Mahan D C DC North Central Coordinating Committee on Swine Nutrition (NCCC-42) - - 2014
Grains grown in various regions of the United States vary in their innate or natural Se contents. A regional study evaluated the effects of adding inorganic Se (sodium selenite) or organic Se (Se yeast) to diets with differing innate Se contents. A 2 × 2 + 1 factorial experiment evaluating ...
Chawda Hiren M HM Pacific Medical College & Hospital, Udaipur, Rajasthan, India. Electronic address: - - 2014
Lipid-lowering and antioxidant activities of a hydroalcoholic extract of Cyperus scariosus Linn. root (HCS) were evaluated in guinea pigs fed with a high cholesterol diet. Serum lipid profile (total cholesterol, triglycerides, LDL-C, VLDL-C, and HDL-C), atherogenic indices and serum enzymes (ALT, AST, ALP, LDH, and CK-MB) were performed in each ...
Runge Jurgen H JH Department of Radiology, Academic Medical Center, University of Amsterdam, Meibergdreef 9, PB 22660, 1100 DD Amsterdam, The Netherlands. Electronic address: - - 2014
To diagnose hepatic steatosis with noninvasive magnetic resonance (MR)-based measurements, threshold values of liver fat percentages are used. However, these differ between studies. Consequently, the choice of threshold values influences diagnostic accuracy, especially in subjects with borderline hepatic steatosis. In this study, we compared (1)H-MR spectroscopy (MRS) and biochemically determined ...
Rezapour-Firouzi Soheila S Neurosciences Research Center, University of Medical Sciences, Tabriz, Iran; School of Nutrition and Health, University of Medical Sciences, Tabriz, Iran. Electronic address: - - 2014
It is unknown whether diets with a high dietary total antioxidant capacity (TAC) can modify oxidative stress, low-grade inflammation, or liver dysfunction, all of which are risk factors for multiple sclerosis disease. This study assesses alanine amino-transferase (ALT), aspartate-aminotransferase (AST) and gamma-glutamyl transferase (GGT) activities in MS patients treated with ...
Nikolic Dragana D Biomedical Department of Internal Medicine and Medical Specialties, University of Palermo, - - 2014
ETC-1002 is a new investigational low density lipoprotein cholesterol (LDL-C)-lowering agent (Esperion Therapeutics, Inc.). ETC-1002 is a dicarboxylic acid derivative with a novel mechanism of action targeting two hepatic enzymes - adenosine triphosphate-citrate lyase (ACL) and adenosine monophosphate-activated protein kinase (AMPK), inhibiting sterol and fatty acid synthesis and promoting mitochondrial ...
Song M M Division of Animal Science, Gwangju, 500-757, Republic of - - 2014
We investigated the probiotic properties of Lactobacillus acidophilus NS1, such as acid resistance, bile tolerance, adherence to HT-29 cells, and cholesterol assimilation activity. In an animal study, 7-wk-old male C57BL/6 mice were fed a normal diet, a high-fat diet (HFD), or an HFD with L. acidophilus NS1 (ca. 1.0 × ...
Son Yonghae Y School of Korean Medicine, Pusan National University , Gyeongnam, South Korea - - 2014
Abstract Vigna species are important food resources and are traditionally used for the treatment of various diseases. In this study, we examined the inhibitory effects of Vigna nakashimae (VN) extract on high-fat diet (HFD)-induced hepatic steatosis and elucidated the molecular mechanisms. C57BL/6J mice were fed an HFD with or without ...
1 2 3 4 5 6 7 8 9 10 >