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Geurts Aron M AM From the Departments of Physiology (A.M.G., D.L.M., P.L., M.M.S., T.M.K., C.Y., B.T.E., J.K., M.L., A.W.C.), Pediatrics (E.C.), and Cardiovascular Research Center (A.M.G.), Medical College of Wisconsin, Milwaukee. - - 2014
Environmental exposure of parents or early in life may affect disease development in adults. We found that hypertension and renal injury induced by a high-salt diet were substantially attenuated in Dahl SS/JrHsdMcwiCrl (SS/Crl) rats that had been maintained for many generations on the grain-based 5L2F diet compared with SS/JrHsdMcwi rats ...
Singh Vishal V Pharmacology Division, CSIR-Central Drug Research Institute,B.S. 10/1, Sector 10, Sitapur Road, Jankipuram Extension,Lucknow226 - - 2014
In the present study, the anti-atherosclerotic effect and the underlying mechanism of curcuma oil (C. oil), a lipophilic fraction from turmeric (Curcuma longa L.), was evaluated in a hamster model of accelerated atherosclerosis and in THP-1 macrophages. Male golden Syrian hamsters were subjected to partial carotid ligation (PCL) or FeCl3-induced ...
Hamazaki Tomohito T Toyama Jonan Onsen Daini Hospital, Taromaru-nishimachi, Toyama City, Toyama 9398271, - - 2014
A diet rich in omega-3 polyunsaturated fatty acids (PUFAs) may decrease risk of cardiovascular disease by improving the blood lipid profile. The purpose of this review was to (1) determine if fish oil (omega-3) consumption increased the risk of hemorrhaging after a military injury and (2) whether an improvement in ...
Ding Mei M Department of Cardiology, China-Japan Union Hospital of Jilin University, Changchun, Jilin 130033, P.R. - - 2014
Xuezhikang (XZK), an extract of red yeast rice, has been widely used for the management of hyperlipidemia and coronary heart disease (CHD); however, the effects of XZK treatment on kidney injury have not yet been fully identified. The aim of the current study was to evaluate the effects of XZK ...
Spiteller Gerhard G University of Bayreuth, Universitätsstr. 30, 95445 Bayreuth (Germany). - - 2014
Cells respond to alterations in their membrane structure by activating hydrolytic enzymes. Thus, polyunsaturated fatty acids (PUFAs) are liberated. Free PUFAs react with molecular oxygen to give lipid hydroperoxide molecules (LOOHs). In case of severe cell injury, this physiological reaction switches to the generation of lipid peroxide radicals (LOO(.) ). ...
Mychasiuk Richelle R Alberta Children's Hospital Research Institute, University of Calgary, Faculty of Medicine, Heritage Medical Research Building Room 274, 3330 Hospital Drive NW, Calgary, AB - - 2014
Mild traumatic brain injury (mTBI) or concussion affects a large portion of the population and although many of these individuals recover completely, a small subset of people experience lingering symptomology and poor outcomes. Little is known about the factors that affect individual susceptibility or resilience to poor outcomes after mTBI ...
Shambayati Maryam M Department of Pharmacology and Neuroscience and Institute for Aging and Alzheimer's Disease Research, University of North Texas Health Science Center at Fort Worth, 3500 Camp Bowie Boulevard, Fort Worth, Texas - - 2014
Dietary soy and soy isoflavones ar e neuroprotective in experimental cerebral ischemia. Because the isoflavones in soy that are responsible for this neuroprotective effect act as phytoestrogens, we hypothesized that they would mimic the beneficial effects of estrogens on the innate inflammatory response to cerebral ischemia. Ovariectomized Sprague-Dawley rats were ...
Dussault Sylvie S Cardiovascular Research, Centre de Recherche du CHUM (CRCHUM), Montréal, Québec, - - 2014
Background: Elsibucol is a metabolically stable derivative of probucol with antioxidant, anti-inflammatory and antiproliferative properties. Here we investigated the effect of elsibucol on the development of atherosclerosis following arterial injury in hypercholesterolemic rabbits. Methods and results: New Zealand White rabbits were fed a high cholesterol diet that was supplemented or ...
Yu Hai H Department of Anesthesiology, University of Virginia, Charlottesville, Virginia, 22908, USA; Department of Anesthesiology and Translational Neuroscience Center, West China Hospital, Sichuan University, Chengdu, 610041, - - 2014
High-fat diet (HFD) contributes to the increased prevalence of obesity and hyperlipidemia in young adults, a possible cause for their recent increase in stroke. Isoflurane post-treatment provides neuroprotection. Isoflurane post-treatment induced neuroprotection in HFD-fed mice was determined. Six-week old CD-1 male mice were fed HFD or regular diet (RD) for ...
Atashroo David D Stanford, Menlo Park, and Palo Alto, Calif. From the Hagey Laboratory for Pediatric Regenerative Medicine, Department of Surgery, Plastic and Reconstructive Surgery Division, and the Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine; the Departments of Materials Science and Engineering and Bioengineering, Stanford University; the TauTona Group; and the Plastic Surgery Center of Palo - - 2014
Although fat grafting can address many soft-tissue deficits, results remain inconsistent. In this study, the authors compared physical properties of fat following injection using an automated, low-shear device or the modified Coleman technique. Lipoaspirate was obtained from nine patients and processed for injection using either a modified Coleman technique or ...
Poissonnier Laure-Anne LA Research Center on Animal Cognition, The National Center for Scientific Research and Toulouse University, Toulouse, - - 2014
A key determinant of the relationship between diet and longevity is the balance of protein to carbohydrate in the diet. Eating excess protein relative to carbohydrate shortens lifespan in solitary and social insects. Here we explored how lifespan and behavior in ants was affected by the quality of protein ingested ...
Rafiq Kazi K Department of Pharmacology, Faculty of Medicine, Kagawa University, Kagawa, - - 2014
A growing body of evidence indicates that renal tissue injuries are reversible. We investigated whether dietary salt reduction with the combination therapy of angiotensin II type 1 receptor blocker (ARB) plus calcium channel blocker (CCB) reverses renal tissue injury in Dahl salt-sensitive (DSS) hypertensive rats. DSS rats were fed a ...
Davis Kathryn - - 2013
Background:The use of autologous fat for augmentation has become common practice among plastic surgeons for both cosmetic and reconstructive procedures. Previously reported data suggest that the method of fat extraction can have profound effects on adipocyte viability and subsequent fat graft survival.Objective:The authors describe a pilot study comparing a new ...
Kim Jihye - - 2013
We report the microfluidic production of spherical and non-spherical fat particles from crystallizable oils. The method is based on microfluidic generation of oil droplets at a cross-junction followed by thermal solidification downstream in a microcapillary. We vary the drop production conditions and the device temperature and demonstrate that the size, ...
van Calcar Sandra C - - 2012
Phenylketonuria (PKU), an inborn error in phenylalanine metabolism, requires lifelong nutrition management with a low-phenylalanine diet, which includes a phenylalanine-free amino acid-based medical formula to provide the majority of an individual's protein needs. Compliance with this diet is often difficult for older children, adolescents, and adults with PKU. The whey ...
Tzeng Thing-Fong - - 2012
Emodin is an active herbal component traditionally used in China for treating a variety of diseases. The aim of this study was to examine the effect of emodin on the reducing lipid accumulation in white adipose tissue of high-fat diet-fed rats, and on the regulation of the expression of the ...
Chen W-L - - 2012
AIMS/HYPOTHESIS: Sirtuin 1 (SIRT1) is a longevity-associated protein, which regulates energy metabolism and lifespan in response to nutrient deprivation. It has been proposed to be a therapeutic target for obesity and metabolic syndrome. We investigated whether α-lipoic acid (ALA) exerts a lipid-lowering effect through regulation of SIRT1 activation and production ...
Yoo Dae Young - - 2012
In this study, we challenged pyridoxine to mice fed a high-fat diet (HFD) and investigated the effects of pyridoxine on HFD-induced phenotypes such as blood glucose, reduction of cell proliferation and neuroblast differentiation in the dentate gyrus using Ki67 and doublecortin (DCX), respectively. Mice were fed a commercially available low-fat ...
Cutullic E - - 2012
The overall reproductive performance has decreased over the last decades, involving changes in cyclicity, oestrous behaviour and fertility. High milk yield (MY), low body condition score (BCS) and large body condition (BC) loss have been identified as risk factors. However, these effects are often confounded, as high MY and body ...
Kim Dae-Young - - 2012
Obesity, a chronic metabolic disorder, is characterized by enlarged fat mass and dysregulation of lipid metabolism. The medicinal plant, Boesenbergia pandurata (Roxb.) Schltr., has been reported to possess anti-oxidative and anti-inflammatory properties; however, its anti-obesity activity is unexplored. The present study was conducted to determine whether B. pandurata extract (BPE), ...
Delgado Denia Caridad - - 2011
The aim of this paper was to present the main results obtained in Cuba on the effects of feeding tropical trees and shrubs on rumen methanogenesis in animals fed with low quality fibrous diets. More than 20 tree and shrub foliages were screened for phytochemicals and analyzed for chemical constituents. ...
Watkins Deborah J DJ Center for Environmental Health and Technology, Brown University, Providence, Rhode Island, United States. - - 2012
Our objectives were to determine relative contributions of diet and dust exposure from multiple microenvironments to PentaBDE body burden, and to explore the role of handwipes as a measure of personal exposure to PentaBDE. We administered a food frequency questionnaire and collected serum, dust (office, main living area, bedroom, and ...
Höcherl Nicole - - 2011
In modern managed agro-ecosystems, the supply of adequate food from blooming crops is limited to brief periods. During periods of pollen deficiencies, bees are forced to forage on alternative crops, such as maize. However, pollen of maize is believed to be a minor food source for bees as it is ...
Tan Jianguo - - 2011
The insidious flower bug, Orius insidiosus (Say) (Heteroptera: Anthocoridae) is an important surrogate species for assessing potential effects of plant-incorporated protectants (PIPs) on nontarget heterotrophic predators. In this study, a continuous dietary exposure system was optimized by assessing the effect of diet composition and age on the survival and development ...
Osuga I M - - 2011
Twenty growing Small East African goats were used to determine the effects of feeding sun-dried leaves of the browse forages Berchemia discolor and Zizyphus mucronata as supplements to low-quality basal diet, Rhodes grass (Chloris gayana) hay, on voluntary feed intake (VFI), digestibility and growth performance. The grass hay and maize ...
Maughan Curtis - - 2011
Ten panelists were selected from the local community to develop a meat lexicon composed of 18 terms that describe flavor attributes found in red meats. This flavor lexicon was used to compare the flavor profile of meat from beef cattle finished on grass or grain. Steaks from grass-fed animals were ...
Gardner B B Health Behaviour Research Centre, Department of Epidemiology & Public Health, University College London, London, UK. - - 2011
Excessive pregnancy weight gain is associated with adverse maternal and child health outcomes. Intervention developers have assumed that adopting a healthier diet and increasing physical activity in pregnancy can limit weight gain, but evaluations of such interventions have yielded mixed results. Recent reviews of this literature have not identified defining ...
Lin Yan - - 2011
The objective of the present study was to investigate the effects of the addition of fibre and the antioxidant N-acetylcysteine (NAC) to fat-rich diets on fetal intrauterine development in rats. A total of eighty virgin female Sprague-Dawley rats were fed a control diet, a high-fat diet (HF), a high-fat and ...
Król Ewelina - - 2011
Although maternal, fetal, and placental mechanisms compensate for disturbances in the fetal environment, any nutritional inadequacies present during pregnancy may affect fetal metabolism, and their consequences may appear in later life. The aim of the present study is to investigate the influence of maternal diet during gestation on Fe, Zn, ...
Strakovsky Rita S - - 2011
In insulin resistance and type II diabetes, there is an elevation of hepatic gluconeogenesis, which contributes to hyperglycaemia. Studies in experimental animals have provided evidence that consumption of high fat (HF) diets by female rats programs the progeny for glucose intolerance in adulthood, but the mechanisms behind the in utero ...
Bergeron Christine M - - 2011
Organisms born into the same contaminated environment as their parents can be exposed both maternally and environmentally to contaminants, potentially placing them at greater risk of adverse effects than when exposed via either of the two pathways independently. We examined whether embryonic exposure to maternally derived mercury (Hg) interacts with ...
van de Merwe Jason P - - 2011
The bioaccumulation and maternal transfer of 2,2',4,4'-tetrabromodiphenyl ether (PBDE 47) were investigated in the marine medaka (Oryzias melastigma) following dietary exposure, in which PBDE 47 was bioencapsulated into brine shrimp (Artemia sp.) and fed daily to male-female pairs of medaka. In the accumulation experiment, each 2-month-old (pre-breeding) medaka were provided ...
Gondret F - - 2011
Intra-uterine growth retardation in piglets is associated to neonatal losses and a greater susceptibility to fat deposition in the long term. Dietary l-arginine supplementation to gilts during early gestation has been proposed as a way to enhance fetal survival. This study aims to investigate the effects of variation in fetal ...
Jahan-Mihan Alireza - - 2011
We hypothesized that protein source in the nutritionally adequate AIN 93G diets fed during gestation, lactation and weaning, influences food intake (FI) regulation in male offspring of Wistar rats. Pregnant rats were fed either the recommended casein (C) or soy protein (S) diet during gestation (Exp 1) or during gestation ...
Schaible Tiffany D - - 2011
Developmental epigenetic changes, such as DNA methylation, have been recognized as potential pathogenic factors in inflammatory bowel diseases, the hallmark of which is an exaggerated immune response against luminal microbes. A methyl-donor (MD) diet can modify DNA methylation at select murine genomic loci during early development. The components of the ...
Ferguson-Smith Anne C - - 2011
Maternal nutrition and metabolism are critical determinants of adult offspring health. Recent reports describe adverse offspring outcomes associated with the father's diet, indicating nongenetic inheritance of paternal experience. Determining underlying mechanisms may require reconsideration of our understanding of the heritability of epigenetic states.
Dwyer Cathy M - - 2011
The present study investigated whether the genetic growth characteristics (fast or slow growing, lean or fat) of a mother influences her ability to partition nutrients to developing offspring. A total of sixty-one pregnant mice of three selected lines were used: fast-growing, relatively fat (FF, n 19); fast-growing, relatively lean (FL, ...
Radunz A E - - 2011
Mature pregnant crossbred ewes (n = 90) were used in a randomized complete block design and assigned to 1 of 3 winter-feeding systems differing in primary feed source: haylage (HL), limit-fed corn (CN), or limit-fed dried distillers grains (DDGS). Effects of these winter-feeding strategies on ewe and lamb performance were ...
Kondo Atsuo - - 2011
To quantify the consumed amount of dietary folate and to evaluate effects of folic acid and balanced diets on serum folate concentrations. Food records collected from 641 pregnant women were assessed to quantify the consumed amount of dietary folate for a 6-year period from 2003 to 2008. Changes in serum ...
Zeisel Steven H SH Department of Nutrition, UNC Nutrition Research Institute at Kannapolis, University of North Carolina at Chapel Hill, 500 Laureate Way, Room 2218, Kannapolis, NC 28081, USA. - - 2011
The consequences of fetal exposure to alcohol are very diverse and the likely molecular mechanisms involved must be able to explain how so many developmental processes could go awry. If pregnant rat dams are fed alcohol, their pups develop abnormalities characteristic of fetal alcohol spectrum disorders (FASD), but if these ...
Nylén Hanna - - 2011
PURPOSE: The purpose of this study was to determine the 4β-hydroxycholesterol to cholesterol ratio in mothers and neonates at the time of birth and 4 months post-partum. METHOD: 21 mothers and 22 neonates were recruited at the delivery ward at Karolinska University Hospital, Huddinge, Sweden. Blood samples taken from mothers and ...
Wright Thomas - - 2011
Contemporary trends in obesity mean that research into whether unbalanced diets could impact on behavioural traits became increasingly important. The timing of exposure to obesity is particularly important, as sensitive periods during development have been identified where dietary extremes play a critical role in determining adult risk of physiological dysfunction. ...
McAfee A J - - 2011
Red meat from grass-fed animals, compared with concentrate-fed animals, contains increased concentrations of long-chain (LC) n-3 PUFA. However, the effects of red meat consumption from grass-fed animals on consumer blood concentrations of LC n-3 PUFA are unknown. The aim of the present study was to compare the effects on plasma ...
Alaux Cédric - - 2011
Malnutrition is a major factor affecting animal health, resistance to disease and survival. In honey bees (Apis mellifera), pollen, which is the main dietary source of proteins, amino acids and lipids, is essential to adult bee physiological development while reducing their susceptibility to parasites and pathogens. However, the molecular mechanisms ...
Turk Harmony F HF Program in Integrative Nutrition and Complex Diseases, Texas A&M University, College Station, TX, - - 2011
The biological properties of polyunsaturated fatty acid (PUFA) classes have been the source of much contention. For example, n-3 PUFA are chemoprotective, whereas n-6 PUFA may promote tumor development. Since dietary components can have combinatorial effects, we further examined the apoptotic properties of n-3 or n-6 fatty acids when combined ...
Levesque C L - - 2011
Current AA recommendations for sows are to provide a fixed amount of AA intake throughout gestation based on the assumption that there is a constant demand for AA; however, the demand for nutrients changes from maternal lean tissue in early gestation to fetal and mammary growth in late gestation. The ...
Hendriksma Harmen P - - 2011
The ecologically and economic important honey bee (Apis mellifera) is a key non-target arthropod species in environmental risk assessment (ERA) of genetically modified (GM) crops. Honey bee larvae are directly exposed to transgenic products by the consumption of GM pollen. But most ERA studies only consider responses of adult bees, ...
Grant Wilmon F WF Neuroscience Graduate Program, Oregon Health & Science University, Portland, Oregon, United States of - - 2011
To begin to understand the contributions of maternal obesity and over-nutrition to human development and the early origins of obesity, we utilized a non-human primate model to investigate the effects of maternal high-fat feeding and obesity on breast milk, maternal and fetal plasma fatty acid composition and fetal hepatic development. ...
Rogers Lynette K LK Center for Perinatal Research, The Ohio State University, Columbus, OH 43205, USA. - - 2011
DHA is a long-chain fatty acid that has potent antiinflammatory properties. Whereas maternal DHA dietary supplementation has been shown to improve cognitive development in infants fed DHA-supplemented milk, the antiinflammatory effects of maternal DHA supplementation on the developing fetus and neonate have not been extensively explored. Pregnant C3H/HeN dams were ...
Shukla Pradeep K PK Department of Psychiatry and Behavioral Sciences, The Asher Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, - - 2011
Fetal alcohol spectrum disorder (FASD) is a leading cause of nongenetic mental retardation and other neurodevelopmental deficits. Earlier diagnosis of FASD would greatly improve prognosis for individuals and families affected by this disorder. Here, we identify candidate placental biomarkers in an animal model of FASD that recapitulates many aspects of ...
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