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Paneni Francesco F *Cardiology Unit, Department of Medicine, Karolinska University Hospital, Stockholm, - - 2015
The incidence of stroke and myocardial infarction increases in aged patients and it is associated with an adverse outcome. Considering the aging population and the increasing incidence of cardiovascular disease, the prediction for population well-being and health economics is daunting. Accordingly, there is an unmet need to focus on fundamental ...
Helle Samuli S Section of Ecology, Department of Biology, University of Turku, 20014 Turku, Finland - - 2014
A shift from nomadic foraging to sedentary agriculture was a major turning point in human evolutionary history, increasing our population size and eventually leading to the development of modern societies. We however lack understanding of the changes in life histories that contributed to the increased population growth rate of agriculturalists, ...
Ohlberger Jan J http://orcid.org/0000-0001-6795-240X Centre for Ecological and Evolutionary Synthesis, Department of Biosciences, University of Oslo, PO Box 1066 Blindern, 0316 Oslo, Norway - - 2014
Climate-induced shifts in the timing of life-history events are a worldwide phenomenon, and these shifts can de-synchronize species interactions such as predator-prey relationships. In order to understand the ecological implications of altered seasonality, we need to consider how shifts in phenology interact with other agents of environmental change such as ...
Gryshchenko Mykola Grygorievich MG V.I. Gryshchenko Clinic for Reproductive Medicine , Kharkov , - - 2014
Abstract In this article, some factors were evaluated for their impact on embryo morphokinetics during assisted reproductive technology (ART) cycles. We detected significant differences in the fourth cell division time (t5) of embryos obtained after controlled ovarian stimulation in long GnRH agonists and GnRH antagonist protocols. We also found that ...
Harada Mikio M Department of Orthopaedic Surgery, Yamagata University Faculty of Medicine, Iida-Nishi, Japan. Electronic address: - - 2014
Although medial epicondylar fragmentation of the humerus is a reported elbow injury in junior tennis players, there have been only a few studies on this entity, and none have investigated the characteristics and prognosis of medial epicondylar fragmentation. Forty-one male junior tennis players, aged 11 to 14 years (mean, 13 years), underwent ...
Stadler Tanja T Department of Biosystems Science and Engineering, Eidgenössische Technische Hochschule (ETH), Zurich, - - 2014
Abstract Many studies have tried to identify factors that explain differences in numbers of species between clades against the background assumption that older clades contain more species because they have had more time for diversity to accumulate. The finding in several recent studies that species richness of clades is decoupled ...
Cortright Catherine C CC Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY - - 2014
Objective-To characterize signalment, clinical features, clinicopathologic variables, hepatic ultrasonographic characteristics, endocrinologic profiles, treatment response, and age at death of Scottish Terriers with progressive vacuolar hepatopathy (VH) with or without hepatocellular carcinoma (HCC). Design-Retrospective case series. Animals-114 Scottish Terriers with progressive VH. Procedures-Electronic databases from 1980 to 2013 were searched for ...
Spiegel Amy M AM Neurocognitive Aging Section, Laboratory of Behavioral Neuroscience, National Institute on Aging, Baltimore, Maryland 21224, - - 2014
Epigenetic modifications of chromatin structure provide a mechanistic interface for gene-environment interactions that impact the individualization of health trajectories across the lifespan. A growing body of research indicates that dysfunctional epigenetic regulation contributes to poor cognitive outcomes among aged populations. Here we review neuroepigenetic research as it relates to cognitive ...
Tator Charles H CH *Department of Neurosurgery, University of Toronto, and Toronto Western Hospital, Toronto, Ontario, Canada; ‡Canadian Sports Concussion Project, Toronto Western Hospital, Toronto, Ontario, - - 2014
There are still many unanswered questions about postconcussion syndrome (PCS) in sports and recreation. The predictors of PCS are unknown, although a history of previous concussion has been suspected. To explore the clinical features and demography of PCS in athletes. A retrospective cohort study was performed by chart review of ...
Simon Melissa A MA Northwestern University, Chicago, IL, USA - - 2014
Loneliness is an important indicator of well-being. However, we have limited understanding of loneliness in minority aging populations. This study aims to identify the prevalence of loneliness among U.S. Chinese older adults. Data were drawn from the PINE study, a population-based study of 3,159 U.S. Chinese older adults in the ...
Liu Junxiu J Department of Epidemiology and Biostatistics, Arnold School of Public Health, University of South Carolina, Columbia, South - - 2014
Although the trajectory of blood pressure (BP) with aging is well known, there is a lack of data on how cardiorespiratory fitness (hereafter referred to as fitness) affects age-associated changes in BP. The objective of the study was to investigate whether fitness alters the aging-BP trajectory. A cohort from the ...
Venclíková Kristýna K Institute of Vertebrate Biology, v.v.i., Academy of Sciences of the Czech Republic, Květná 8, 603 65, Brno, Czech - - 2014
A total of 1279 field-collected Ixodes ricinus ticks were screened for Borrelia burgdorferi sensu lato (s.l.) in a natural and an urban ecosystem of Ostrava city (Czech Republic) by using molecular methods. Minimal prevalence rate for Borrelia burgdorferi s.l. in ticks for the urban park Bělský les was found to ...
Jaruratanasirikul Somchit S Department of Pediatrics - - 2014
Abstract Background: In Thailand, studies of growth date back to 1975, but there have been no studies examining any trends in increasing/decreasing growth. Aim: To determine if there have been any secular trends of increasing/decreasing growth and/or ages at puberty in Thai children. Methods: In 2012, a cross-sectional study of ...
Laney Dawn A DA Division of Medical Genetics, Department of Human Genetics, Decatur, Georgia, - - 2014
Purpose:Fabry disease is a pan-ethnic, progressive, X-linked genetic disorder that commonly presents in childhood and is caused by deficient activity of the lysosomal enzyme alpha-galactosidaseA (α-gal A). Symptoms of Fabry disease in the pediatric population are well described for patients over five years of age; however, data are limited for ...
van Dongen Wouter F D WF Konrad Lorenz Institute of Ethology, Department of Integrative Biology and Evolution, University of Veterinary Medicine Vienna, Vienna, Austria, - - 2014
Animal dispersal is associated with diverse costs and benefits that vary among individuals based on phenotype and ecological conditions. For example, females may disperse when males benefit more from defending territories in familiar environments. Similarly, size differences in dispersal propensity may occur when dispersal costs are size-dependent. When individuals do ...
Doyle Lex W LW Departments of Obstetrics and Gynaecology, University of Melbourne, Melbourne, Australia2Paediatrics, University of Melbourne, Melbourne, Australia3The Royal Women's Hospital, Melbourne, Australia4Murdoch Childrens Research Institute, Melbourne, - - 2014
Antenatal magnesium sulfate given to pregnant women at imminent risk of very preterm delivery reduces the risk of cerebral palsy in early childhood, although its effects into school age have not been reported from randomized trials. To determine the association between exposure to antenatal magnesium sulfate and neurological, cognitive, academic, ...
Hu S X SX Zoetis Inc, Veterinary Medicine Research and Development, Kalamazoo, MI, - - 2014
Swine is not only an important species in veterinary medicine research but also a popular animal model for human drug discovery. It is valuable to understand the impact of pig age on abundance and activity of porcine hepatic cytochrome P450 (CYP450). Liver microsomes were prepared from Camborough-29 intact male pigs ...
Ben-Shachar S S Genetic Institute, Dana-Dwek Children's Hospital, Tel Aviv Sourasky Medical Center, Tel Aviv, - - 2014
Nonclassical 21-hydroxylase deficiency (NC21OHD) manifests with various degrees of post natal virilization. The length of CAG repeats of the androgen receptor gene (AR) is inversely correlated to activity of the human androgen receptor (AR) and affects phenotype of several androgen-dependent disorders. The aim of the study was to investigate the ...
Dusseldorp Elise E TNO, Leiden, The Netherlands; Mathematical Institute, Leiden University, Leiden, the - - 2014
To study the impact of lifestyle factors on dental caries experiences in addition to the effect of demographic characteristics at the ages of 9, 15, and 21 years. The data were obtained from the study 'Oral health in children and adolescents in the Netherlands'. Data were collected through questionnaires and a ...
Kessler Matthew J MJ Office of Laboratory Animal Resources, Robert C. Byrd Health Sciences Center, West Virginia University, Morgantown, - - 2014
Tetanus was a major cause of mortality in the free-ranging population of rhesus monkeys on Cayo Santiago prior to 1985 when the entire colony was given its first dose of tetanus toxoid. The immediate reduction in mortality that followed tetanus toxoid inoculation (TTI) has been documented, but the long-term demographic ...
Kuhn Maggie A MA Department of Otolaryngology - Head and Neck Surgery, University of California, Davis, Sacramento, California, - - 2014
Sophisticated descriptions of the highly specialized vocal fold microarchitecture have been available for over three decades, but how this anatomy evolves with growth and aging remains an area of active investigation and, at times, a source of controversy. As our aging population expands and interest in pediatric voice disorders blossoms, ...
Craig Thomas T Integrative Genomics of Ageing Group, Institute of Integrative Biology, University of Liverpool, Liverpool, - - 2014
Multiple studies characterizing the human ageing phenotype have been conducted for decades. However, there is no centralized resource in which data on multiple age-related changes are collated. Currently, researchers must consult several sources, including primary publications, in order to obtain age-related data at various levels. To address this and facilitate ...
Stubbs Brendon B School of Health and Social Care, University of Greenwich, London, - - 2014
Physical inactivity and sedentary behavior (SB) are leading causes of mortality. We investigated if older adults with chronic musculoskeletal pain (CMP) are more sedentary than a group of similar age and sex without CMP and possible contributory factors to this. In this multisite observational study, 285 community-dwelling older adults (response ...
Reinbott Anika - - 2014
Background: Adequate young child feeding practices are influenced by a multitude of factors which affect growth and development. A combination of indicators is needed to explain the role of complementary feeding practices in growth retardation. Methods: A cross-sectional nutrition baseline survey was conducted in rural Cambodia in September 2012. Villages ...
Koh Young Wha YW Department of Pathology, Ajou University School of Medicine, Suwon, South - - 2014
Recent studies suggest that absolute lymphocyte count, absolute monocyte count and their ratio [lymphocyte/monocyte ratio (LMR)] at diagnosis may predict survival in classical Hodgkin lymphoma (cHL). Here, we investigated the prognostic significance of LMR in cHL patients in relation to age of patients. Subjects included 351 cHL patients (age range ...
Gielen E E Gerontology and Geriatrics, Department of Clinical and Experimental Medicine, KU Leuven, Leuven, Belgium, - - 2014
The aim of this study was to determine whether bone turnover markers (BTMs) predict changes in areal bone mineral density (aBMD) in middle-aged and elderly European men. Older men with high bone turnover are at a higher risk of accelerated hip bone loss, but the clinical utility of BTMs in ...
Allemand Mathias M University of - - 2014
Are there age differences in gratitude from early adulthood to old age? The current studies tested several ways by which an association between age and dispositional gratitude may present, by considering multiple measures on both fronts. We used data from three cross-sectional studies (total N = 1736, total age range: ...
Simmons L W LW Centre for Evolutionary Biology, School of Animal Biology, The University of Western Australia, Crawley, WA, - - 2014
Female choice based on male secondary sexual traits is well documented, although the extent to which this selection can drive an evolutionary divergence in male traits among populations is less clear. Male field crickets Teleogryllus oceanicus attract females using a calling song and once contacted switch to courtship song to ...
Gillespie Stephanie R SR Entomology and Nematology Department, University of Florida, P.O. Box 110620, Gainesville, FL, 32611, USA; Current Address: Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, Box 1022, New York, NY, 10029-6574, USA. - - 2014
Sexual selection is often assumed to be strong and consistent, yet increasing research shows it can fluctuate over space and time. Few experimental studies have examined changes in sexual selection in response to natural environmental variation. Here, we use a difference in resource quality to test for the influence of ...
Nikolich-Žugich Janko J Department of Immunobiology, University of Arizona College of Medicine, Tucson, AZ 85724; and Arizona Center on Aging, University of Arizona College of Medicine, Tucson, AZ 85724 - - 2014
Until the mid-20th century, infectious diseases were the major cause of morbidity and mortality in humans. Massive vaccination campaigns, antibiotics, antivirals, and advanced public health measures drastically reduced sickness and death from infections in children and younger adults. However, older adults (>65 y of age) remain vulnerable to infections, and ...
Satake Masahiro - - 2014
Abstract Human T-lymphotropic virus type 1 (HTLV-1) is highly endemic in the Kyushu/Okinawa region of Japan. A nationwide investigation verified the frequency of HTLV-1 carriers among first-time blood donors and the occurrence of newly diagnosed adult T-cell leukemia/lymphoma (ATL) cases from 2007 through 2008. After adjusting for differences in capture ...
Smith Katherine P KP Roseman University of Health Sciences, South Jordan, - - 2014
Individuals with gender dysphoria experience distress associated with incongruence between their biologic sex and their identified gender. Gender dysphoric natal males receive treatment with antiandrogens and estrogens to become feminized (transsexual females), whereas natal females with gender dysphoria receive treatment with androgens to become masculinized (transsexual males). Because of the ...
Chen-Edinboro Lenis P LP Department of Mental Health,Johns Hopkins Bloomberg School of Public - - 2014
ABSTRACT Background: We determined the association between neighborhood socio-environmental factors and insomnia symptoms in a nationally representative sample of US adults aged >50 years. Methods: Data were analyzed from two waves (2006 and 2010) of the Health and Retirement Study using 7,231 community-dwelling participants (3,054 men and 4,177 women) in ...
Scuteri Angelo A From the Hospital San Raffaele Pisana-Istituto Ricovero e Cura a Carattere Sceintifico (IRCCS), Rome, Italy (A.S.); Laboratory of Cardiovascular Science, National Institute of Aging, Baltimore, MD (C.H.M., J.B.S., K.V.T., H.S., E.G.L.); Loyola University Maryland, Baltimore (C.H.M.); Istituto di Ricerca Genetica e Biomedica (IRGB), Consiglio Nazionale delle Ricerche, c/o Cittadella Universitaria di Monserrato, Monserrato, Cagliari, Italy (M.O., L.A.P.F., F.L., M.G.P., A.D.); Johns Hopkins School of Medicine, Baltimore, MD (M.A.); and MedStar Heart Institute, Washington, DC - - 2014
The age-associated increase in arterial stiffness has long been considered to parallel or to cause the age-associated increase in blood pressure (BP). Yet, the rates at which pulse wave velocity (PWV), a measure of arterial stiffness, and BP trajectories change over time within individuals who differ by age and sex ...
Wong Christopher Kevin CK , Program in Physical Therapy, Columbia University, 10032 New York, NY , USA. - - 2014
Objective: Falls are common among adults with leg amputations and associated with balance confidence. But subjective confidence is not equivalent with physical ability. This multivariate analyses of community-dwelling adults with leg amputations examined relationships among individual characteristics, falls, balance ability and balance confidence. Design: Cross-sectional study. Subjects/Patients: Community-dwelling adults with ...
Chon Don Soo DS Auburn University at Montgomery, AL, USA - - 2014
Given the scarcity of prior studies, the current research introduced country-level variables, along with individual-level ones, to test how they are related to an individual's perceived risk of burglary (PRB) and fear of crime (FC), separately, by using mixed-level logistic regression analyses. The analyses of 104,218 individuals, residing in 50 ...
Bae Hyun Jung HJ Dept. of Food Science and Nutrition, Kyungpook National Univ, Daegu, 702-701, Republic of - - 2014
The effects of aging process on the ginsenosides and antioxidant activity of ginseng was investigated. Fresh ginseng roots were aged in oven at 70 or 80 °C for 7, 14, 21, or 28 d. Their ginsenosides, phenolics, and antioxidant activity were analyzed. Ginseng aged at 80 °C for 14 d ...
Hsu Cheng-Chen CC 1Department of Anatomy, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan, hcc47223@tmu.edu.tw 2Department of Pathology, Hualien Tzu Chi Medical Center, Hualien, Taiwan, pathology@email.com 3Center for Liberal Arts, College of Humanities and Social Sciences, Taipei Medical University, Taipei, Taiwan, kevinkan@tmu.edu.tw 4Department of Sports Training Science - Balls, National Taiwan Sport University, Taoyuan, Taiwan, suling@ntsu.edu.tw 5Department of Anatomy, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan, thfong@tmu.edu.tw 6Center for Liberal Arts, College of Humanities and Social Sciences, Taipei Medical University, Taipei, Taiwan, tomchi77@tmu.edu.tw 7Center for Liberal Arts, College of Humanities and Social Sciences, Taipei Medical University, Taipei, Taiwan, cchyuan@tmu.edu.tw 8Department of Sports Medicine, Kaohsiung Medical - - 2014
The ratio of the length of the second finger (index finger) to the fourth finger (ring finger) (2D:4D ratio) is a putative marker for prenatal hormones. Physiological research has suggested a low 2D:4D ratio correlates with high athletic ability. Athletes of specific sports (e.g., American football) have lower 2D:4D ratios ...
Chiesa Anna Maria AM Cardio-Thoracic Radiology, S.Orsola-Malpighi University Hospital, Bologna, - - 2014
The senile lung undergoes physiologic changes that are well known but have not been investigated with ultrasound (US). Thus, the aim of our study was to compare the US appearances of the lungs in a group of healthy, nonsmoker elderly subjects with those in a group of young subjects. One ...
Slockers Marcel T MT 1 Department of Public Health, Erasmus MC, University Medical Center Rotterdam, Rotterdam, Netherlands - - 2014
Homeless people have a 3-5-fold increased risk of mortality compared with general populations. After 2005, policy actions being implemented in Rotterdam, the Netherlands, have improved the living conditions of this group. This study examines the effect of policies aimed at improving living conditions on mortality risks of the homeless. Register-based ...
Karottki Dorina Gabriela DG Department of Public Health, University of Copenhagen, Øster Farimagsgade 5, 1014 Copenhagen K, - - 2014
This cross-sectional study investigated the relationship between exposure to airborne indoor and outdoor particulate matter (PM) and cardiovascular and respiratory health in a population-based sample of 58 residences in Copenhagen, Denmark. Over a 2-day period indoor particle number concentrations (PNC, 10-300nm) and PM2.5 (aerodynamic diameter<2.5μm) were monitored for each of ...
Qiao Jichao J Université de Lyon, CNRS, INSA-Lyon, MATEIS UMR5510, F-69621 Villeurbanne, - - 2014
The influence of physical aging on the β relaxation in La60Ni15Al25 bulk metallic glass has been investigated by mechanical spectroscopy. The amplitude of the β relaxation (ΔG″) decreases while its relaxation time (τβ) increases during aging. We find that, as in organic glasses, the changes of ln (τβ) and ln (ΔGmax ) are ...
Gheorghe Maria M Institute of Health Policy and Management/Institute of Health Technology Assessment, Erasmus University Rotterdam, Rotterdam, The Netherlands, - - 2014
Although many countries' populations have experienced increasing life expectancy in recent decades, quality of life (QoL) trends in the general population have yet to be investigated. This paper investigates whether QoL changed for the general Dutch population over the period 2001-2008. A beta regression model was employed to address specific ...
Huétink Kasper K Department of Orthopedics, Leiden University Medical Center, P.O. Box 9600, 2300 RC, Leiden, The Netherlands, - - 2014
The objective of this study was to identify risk factors for knee osteoarthritis (OA) development in a young to middle-aged population with sub-acute knee complaints. This, in order to define high risk patients who may benefit from early preventive or future disease modifying therapies. Knee OA development visible on radiographs ...
Libby G G Medical Research Institute, University of Dundee, - - 2014
Small studies have examined the effect of faecal occult blood test (FOBT) screening on the proportion of hospital admissions for colorectal cancer (CRC) classed as an emergency. This study aimed to examine this and short-term outcomes in persons invited for screening compared with a control group not invited. The invited ...
Obayashi Kenji K Department of Community Health and Epidemiology, Nara Medical University School of - - 2014
Background: Melatonin is associated with a variety of diseases in advanced age, including insomnia, depression, and dementia, and its secretion is influenced by light exposure. Although studies in young and middle-aged subjects have shown that females tend to have higher melatonin levels than males, gender differences in melatonin levels among ...
Yamauchi Akihito A Department of Otolaryngology, The University of Tokyo Hospital, Tokyo, Japan. Electronic address: - - 2014
Kymography is an effective method for assessing temporal patterns of vocal fold vibrations. Because kymographic data for a number of normal speakers based on high-speed digital imaging (HSDI) were limited in the literature, this prospective study was conducted to provide normative kymographic HSDI data and clarify gender- and age-related normal ...
Samavat Jinous J Endocrinology Unit, Department of Experimental and Clinical Biomedical Sciences, University of Florence, Florence, - - 2014
To compare spontaneous (Sp-AR) and P-induced acrosome reaction (AR) in spermatozoa of obese and lean subjects. Bariatric unit at a university hospital. Prospective, observational study. Twenty-three obese (mean ± SD body mass index [BMI], 44.3 ± 5.9 kg/m(2)) and 25 age-matched lean (BMI, 24.2 ± 3.0 kg/m(2)) subjects. None. Spontaneous and P-induced ...
Francis Howard W HW Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins University, - - 2014
To identify psychosocial determinants of speech perception (SP) outcome in older adults after cochlear implant (CI) surgery. Retrospective study. Subjects received their CI at age 45 years or older and had at least 12 months of device experience. Independent variables consisted of the Charlson Comorbidity Index, history of depression, length ...
Peter R S RS 1] Agency for Preventive and Social Medicine, Bregenz, Austria [2] Institute of Epidemiology and Medical Biometry, Ulm University, Ulm, - - 2014
BACKGROUND:It is unclear if the body mass index (BMI) associated with minimum all-cause mortality is constant throughout adult life or increasing with age.METHODS:We applied multivariable fractional polynomials to data of the Vorarlberg Health Monitoring and Prevention Program (VHM&PP) to quantify the BMI associated with minimum mortality over age. The analysis ...
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