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Moreno-Villanueva M M University of Konstanz, Molecular Toxicology Group, Department of Biology, D-78457 Konstanz, Germany. Electronic address: - - 2014
Psychological stress has often been described as a feeling of being overwhelmed by the necessity of constant adjustment to an individual's changing environment. Stress affects people of all ages, but the lives of the elderly may particularly be affected. Major changes can cause anxiety leading to feelings of insecurity and/or ...
Reinhart Michael M From the Department of Biological Sciences, Binghamton University, Binghamton, NY (Reinhart, Carney, and Fiumera); and the Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY (Clark). Data deposited at Dryad: - - 2014
Drosophila melanogaster females commonly mate with multiple males establishing the opportunity for pre- and postcopulatory sexual selection. Traits impacting sexual selection can be affected by a complex interplay of the genotypes of the competing males, the genotype of the female, and compatibilities between the males and females. We scored males ...
Habata Yoichi Y Department of Chemistry, Faculty of Science, Toho University, 2-2-1 Miyama, Funabashi, Chiba 274-8510, Japan. - - 2014
Triple-armed cyclens bearing three aromatic side-arms were prepared in three steps from (3R,5S)-3,5-dimethyl-1,4,7,10-tetraazacyclododecane-2,6-dione, and the Ag(+)-ion-induced (1)H NMR and UV-vis spectral changes and X-ray structures suggested that the aromatic side-arms cover the Ag(+) incorporated into the ligand cavities like an insectivorous plant (Venus flytrap).
McCourt Mark E ME Center for Visual and Cognitive Neuroscience, Department of Psychology, North Dakota State University, Fargo, North Dakota, 58108. Electronic address: - - 2014
A variety of visual capacities show significant age-related alterations. We assessed suprathreshold contrast and brightness perception across the lifespan in a large sample of healthy participants (N = 155; 142) ranging in age from 16-80 years. Experiment 1 used a quadrature-phase motion cancelation technique (Blakeslee & McCourt, 2008) to measure ...
Ziegler Dorian V DV Département de Biologie, Ecole Normale Supérieure de Lyon, 46 allée d'Italie, Lyon, 69007, France; Buck Institute for Research on Aging, 8001 Redwood Blvd., Novato, CA, 94945, - - 2014
Cellular senescence is a process that results from a variety of stresses, leading to a state of irreversible growth arrest. Senescent cells accumulate during aging and have been implicated in promoting a variety of age-related diseases. Mitochondrial stress is an effective inducer of cellular senescence, but the mechanisms by which ...
Göeken Kristian L KL Nanobiophysics, MIRA Institute for Biomedical Technology and Technical Medicine, University of Twente, Enschede, The Netherlands. - - 2014
Noble metal nanoparticles possess very large scattering cross-sections, which make them useful as tags in biosensing assays with the potential to detect even single binding events. In this study, we investigated the effects of nanoparticle size on the shift in the light scattering spectrum following formation of Au-Au, Ag-Ag or ...
Imaizumi Kazuhiko K Second Forensic Biology Section, National Research Institute of Police Science, 6-3-1, Kashiwanoha, Kashiwa-shi, Chiba, 277-0882, Japan, - - 2014
We sought to generate data to facilitate forensic facial comparisons. Specifically, we conducted a longitudinal study of alterations in face shape induced by aging. We obtained two three-dimensional facial shape measurements in 171 Japanese males at intervals of approximately 10 years. With this data, we created a homologous model consisting of ...
Gabrieli Paolo P Dipartimento di Medicina Sperimentale, Università degli Studi di Perugia, Perugia 06100, - - 2014
Female insects generally mate multiple times during their lives. A notable exception is the female malaria mosquito Anopheles gambiae, which after sex loses her susceptibility to further copulation. Sex in this species also renders females competent to lay eggs developed after blood feeding. Despite intense research efforts, the identity of ...
Lin Jun J a Hefei National Laboratory for Physical Sciences at the Microscale and School of Life Sciences ; University of Science and Technology of China ; Hefei , - - 2014
Silver nanoparticles (Ag NPs) are cytotoxic to cancer cells and possess excellent potential as an antitumor agent. A variety of nanoparticles have been shown to induce autophagy, a critical cellular degradation process, and the elevated autophagy in most of these situations promotes cell death. Whether Ag NPs can induce autophagy ...
Gao Yuanjin Y Key Laboratory of High Efficiency and Clean Mechanical Manufacture, School of Mechanical Engineering, Shandong University, Jinan 250061, PR - - 2014
This study aims to assess the dynamic cerebral autoregulation (dCA) in response to posture change using wavelet phase coherence (WPCO) of cerebral tissue oxyhemoglobin concentrations (Delta [HbO2]) and arterial blood pressure (ABP) signals in healthy elderly subjects. Continuous recordings of near-infrared spectroscopy (NIRS) and ABP signals were obtained from simultaneous ...
Büttner Sabrina S a Institute of Molecular Biosciences ; University of Graz ; Graz , - - 2014
Abstract As our society ages, neurodegenerative disorders like Parkinson`s disease (PD) are increasing in pandemic proportions. While mechanistic understanding of PD is advancing, a treatment with well tolerable drugs is still elusive. Here, we show that administration of the naturally occurring polyamine spermidine, which declines continuously during aging in various ...
Tartu S S UMR 7372, CNRS-Université de La Rochelle, Villiers-en-bois, France. Electronic address: - - 2014
Seabirds often have high loads of contaminants. These contaminants have endocrine disrupting properties but their relationships with some endocrine mechanisms are still poorly investigated in free-living organisms. This is the case for the stress response which shifts energy investment away from reproduction and redirects it towards survival. In birds, this ...
Kang Shi Hyun SH Departments of aPsychiatry bMental Health Research, Seoul National Hospital cDepartment of Psychiatry, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of - - 2014
We investigated the associations of the LEP-2548A/G and HTR2C-759C/T polymorphisms with long-term clozapine-induced weight changes and baseline BMI in chronic patients with schizophrenia. A total of 113 patients receiving clozapine for at least 1 year were enrolled. Body weight was measured cross-sectionally and data on body weight just before starting ...
Li D X DX Department of Stomatology, Air Force General Hospital PLA, Haidian District, Beijing, - - 2014
Diabetics have an increased prevalence of periodontitis, and diabetes is one of the causative factors of severe periodontitis. Apoptosis is thought to be involved in this pathogenic relationship. The aim of this study was to investigate apoptosis in human periodontal ligament (PDL) fibroblasts induced by advanced glycation end products (AGEs) ...
Li D X DX Department of Stomatology, Air Force General Hospital PLA, Haidian District, Beijing, - - 2014
Diabetics have an increased prevalence of periodontitis, and diabetes is one of the causative factors of severe periodontitis. Apoptosis is thought to be involved in this pathogenic relationship. The aim of this study was to investigate apoptosis in human periodontal ligament (PDL) fibroblasts induced by advanced glycation end products (AGEs) ...
Yang Congwen C State Key Laboratory of Silkworm Genome Biology, Southwest University, Chongqing, - - 2014
Female qualities in males are common in vertebrates but have not been extensively reported in insects. Vitellogenin (Vg) is highly expressed in the female fat body and is generally required for the formation of yolk proteins in the insect egg. Vg upregulation is generally regarded as a female quality in ...
Zhang Jianyong J KLGHEI of Environment and Energy Chemistry, MOE Key Laboratory of Polymeric Composite and Functional Materials, School of Chemistry and Chemical Engineering, Sun Yat-Sen University, Guangzhou, 510275, China. - - 2014
A tetraphenylethylene-based phosphine, 1,1,2,2-tetrakis((4-diphenylphosphino)phenyl)ethylene (TPE-P4), was synthesized and showed novel aggregation-induced and mechano-responsive emission. A mixture of TPE-P4 and Ag(+) could fix atmospheric CO2in situ as carbonate ions in neutral solution to yield a rare 3D metal-organic framework with zeolite-like SOD topology, [Ag2(TPE-P4)CO3]x⊃nH2O (Ag-TPE-P4). Ag-TPE-P4 showed turn-on luminescence of TPE-P4, ...
Zhang Xinchen X School of Biological Sciences, The University of Hong Kong, Pokfulam, Hong Kong. - - 2014
Advanced glycation endproducts (AGEs) are a group of harmful compounds produced either endogenously or during thermal food processing. Once absorbed by humans via food intake, AGEs can cause oxidative cell damage and contribute to pathological development of various diseases. The AGE-inhibitory activity of dietary polyphenols in vitro has been extensively ...
Lim Poon Nian - - 2014
Surface-bound silver ions were demonstrated to be responsible for the antibacterial action of silver, silicon-containing hydroxyapatite (Ag,Si-HA). X-ray photoelectron spectroscopy, transmission electron microscope and induced coupled plasma spectroscopy results suggested that silver ions in the crystal structure diffused towards the crystal surface of Ag,Si-HA, and interacted with adherent Staphylococcus aureus ...
Ulgherait Matthew M Department of Integrative Biology and Physiology, University of California, Los Angeles, Los Angeles, CA 90095, USA; Department of Biological Chemistry, University of California, Los Angeles, Los Angeles, CA 90095, - - 2014
AMPK exerts prolongevity effects in diverse species; however, the tissue-specific mechanisms involved are poorly understood. Here, we show that upregulation of AMPK in the adult Drosophila nervous system induces autophagy both in the brain and also in the intestinal epithelium. Induction of autophagy is linked to improved intestinal homeostasis during aging ...
Maeda Sayaka S Department of Pathophysiology and Therapeutics of Diabetic Vascular Complications, Kurume University School of Medicine, Kurume, - - 2014
Advanced glycation end products (AGEs) not only inhibit DNA synthesis but also play a role in diabetic retinopathy by evoking apoptosis and inflammation in retinal pericytes via interaction with a receptor for AGE (RAGE). Similarly, sulforaphane, which is a naturally occurring isothiocyanate that is found in widely consumed cruciferous vegetables, ...
Martín-Sanchez Ana A Laboratori de Neuroanatomia Funcional Comparada, Department of Functional Biology, Faculty of Biological Sciences, Univ. Valencia, C. Dr. Moliner, 50, 46100 Burjassot, Spain; Laboratori de Neuroanatomia Funcional Comparada, Department of Cell Biology, Faculty of Biological Sciences, Univ. Valencia, C. Dr. Moliner, 50, 46100 Burjassot, - - 2014
This article is part of a Special Issue "Chemosignals and Reproduction". This paper reviews the role of chemosignals in the socio-sexual interactions of female mice, and reports two experiments testing the role of pup-derived chemosignals and the male sexual pheromone darcin in inducing and promoting maternal aggression. Female mice are ...
Baruch Kuti K Department of Neurobiology, Weizmann Institute of Science, Rehovot 76100, - - 2014
Aging-associated cognitive decline is affected by factors produced inside and outside the brain. Using multi-organ genome-wide analysis of aged mice, we found that the choroid plexus, an interface between the brain and the circulation, shows a type I interferon (IFN-I)-dependent gene expression profile, which was also found in aged human ...
Shalev Moran M The Edith and Joseph Fischer Enzyme Inhibitors Laboratory, Schulich Faculty of Chemistry, Technion - Israel Institute of Technology, Haifa 32000, - - 2014
Aminoglycosides (AGs) are highly potent antibacterial agents, which are known to exert their deleterious effects on bacterial cells by interfering with the translation process, leading to aberrant protein synthesis that usually results in cell death. Nearly 45 years ago, AGs were shown to induce read-through activity in prokaryotic systems by ...
Dominchin M F MF Instituto de Investigaciones Biológicas y Tecnológicas (IIByT), Facultad de Ciencias Exactas, Físicas y Naturales (FCEFyN), Universidad Nacional de Córdoba (UNC) and Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), - - 2014
The study evaluated whether different short-term endocrine testicular and adrenocortical responses to short photoperiod exposure can persist over time and particularly when birds exhibit spontaneous cloacal gland recovery. At 11 wk of age, 33 male Japanese quail exposed to long photoperiod were switched to short photoperiod (8L:16D). Another group of males ...
Tan Robert S RS Michael DeBakey VA Medical Center, Houston, TX, USA Baylor College of Medicine, Houston, TX, USA University of Texas, Houston, TX, USA Opal Medical Clinic, Houston, TX, USA Low T Institute, Southlake, TX, USA - - 2014
Testosterone replacement improves quality of life and is aromatized in men in adipose tissues to estrogen. Hyperestrogenism is believed to be harmful to male sexuality. This is a description of our experience of screening 34,016 men in the Low T Centers, of which approximately 50% were converted to treatment. Men ...
Wenzel Jürgen J JJ Institute of Clinical Microbiology and Hygiene, Regensburg University Medical Center, Regensburg, - - 2014
In the past decade, an increasing frequency of acute hepatitis E was noted in Germany and other European countries. Moreover, a high prevalence (17%) of hepatitis E virus (HEV) immunoglobulin G antibodies (anti-HEV) was recently found in the adult German population. Although this alludes to an emerging pathogen, reports from ...
Chan J J Department of Physiology and Pharmacology, Western University, - - 2014
Objective: Hair analysis has been demonstrated to accurately reflect exposure to drug abuse, environmental toxins and exogenous hormones. We tested the feasibility of measuring cortisol and testosterone in hair of healthy and obese subjects. Measurements: A modified immunoassay (ELISA) originally developed for saliva was used. Hair, urine and blood samples ...
Chung Sung Jun SJ Department of Internal Medicine, Hanyang University Guri Hospital, Hanyang University College of Medicine, Guri, - - 2014
The incidence of symptomatic hepatitis A reportedly increased among 20- to 40-year-old Korean during the late 2000s. Vaccination against hepatitis A was commenced in the late 1990s and was extended to children aged <10 years. In the present study we analyzed the changes in the seroprevalence of IgG anti-hepatitis A ...
Krishnan V V VV Department of Chemistry California State University, Fresno, California, 93740; Center for Comparative Medicine, University of California Davis, Davis, California, 95616; Department of Pathology and Laboratory Medicine, University of California School of Medicine, Davis, California, - - 2014
Multiplex microbead immunoassay (MMIA) is a powerful technology for a wide range of biomedical and clinical applications. It is important to study the normal concentration ranges of immunomodulators under different sample preparation conditions and age groups of subjects in order to more precisely determine their reference values for use in ...
Dabaja Ali A - - 2014
Serum testosterone does not correlate with androgen tissue activity, and it is critical to optimize tools to evaluate such activity in males. Ultrasound measurement of bulbocavernosus muscle (BCM) was used to assess the relationship between the number of CAG repeats (CAGn) in the androgen receptor (AR) and the BCM size; ...
Quifer-Rada Paola P Department of Nutrition and Food Science-XARTA-INSA, School of Pharmacy, University of Barcelona, Barcelona, - - 2014
Biomarkers of food consumption are a powerful tool to obtain more objective measurements of dietary exposure and to monitor compliance in clinical trials. In this study, we evaluated the effectiveness of urinary isoxanthohumol (IX) excretion as an accurate biomarker of beer consumption. A dose-response clinical trial, a randomized, crossover clinical ...
Konishi Shoko S Department of Human Ecology, Graduate School of Medicine, The University of Tokyo, Tokyo, 113-0033, Japan; Department of Anthropology, University of Washington, Seattle, WA, - - 2014
Life history theory predicts a trade-off between immunostimulation and growth. Using a cross-sectional study design, this study aims to test the hypothesis that C-reactive protein (CRP) is negatively associated with height-for-age z-scores (HAZ scores) and BMI-for-age z-scores (BAZ scores) among 6- to 19-year olds (N = 426) residing in five Nepalese communities. ...
Steeb Hannah - - 2014
The higher prevalence of Asperger Syndrome (AS) and other autism spectrum conditions in males has been known for many years. However, recent multiplex immunoassay profiling studies have shown that males and females with AS have distinct proteomic changes in serum. Here, we analysed sera from adults diagnosed with AS (males = 14, ...
Zou Yan Y Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, - - 2014
To evaluate the difference of iodine nutritional status between rural and urban residents under the universal salt iodisation policy. A multistage cluster sampling technique was employed in the present cross-sectional study. In total, 3300 rural and 3300 urban households were selected where the investigation was conducted. A total of 8553 ...
Birnbaum Wiebke W Hormonzentrum für Kinder und Jugendliche, Division of Experimental Paediatric Endocrinology and Diabetes, Department of Paediatrics and Adolescent Medicine, University of Lübeck, Lübeck, - - 2014
People with disorders of sex development (DSD) may have impaired sex steroid production or their gonads removed before, during or after adolescence, thus requiring hormone replacement therapy (HRT) to induce puberty and/or maintain secondary sexual characteristics, to optimize bone health, and to promote physical and social well-being. Oestrogens are usually ...
McGovern David P DP Trinity College Institute of Neuroscience, Trinity College Dublin College Green, Dublin, - - 2014
While aging can lead to significant declines in perceptual and cognitive function, the effects of age on multisensory integration, the process in which the brain combines information across the senses, are less clear. Recent reports suggest that older adults are susceptible to the sound-induced flash illusion (Shams et al., 2000) ...
Tseng Hsiu Chen HC Department of Psychiatry, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, 138 Sheng Li Road, North Dist., Tainan 70403, Taiwan; Department of Psychiatry, National Cheng Kung University Hospital, Douliou Branch, Yunlin, - - 2013
Oxytocin (OT) has been shown to play a crucial role in the biology of social interaction. Sex differences associated with this neuropeptide system have been reported. OT may serves as an indicator of interpersonal stress, especially in women. The aim of this study was to investigate the sex-specific associations between ...
Tyagi Pradeep - - 2013
Although epidemiology studies consistently report increased prevalence of overactive bladder (OAB) with age, an accurate deciphering of causative links between the two entities remains elusive. Studies on aged rodent bladder have so far yielded contradictory results on age-associated changes in muscarinic receptors, which highlight the challenge posed by species differences ...
Huertas Mar - - 2013
Mozambique tilapia males congregate in leks where they establish dominance hierarchies and attract females to spawn in sandy pits. Dominant males store more urine than subordinates and the pattern of urination and the high sensitivity of females to male urine suggests chemical signalling via the urine. Here we show that ...
Paradela Emylucy Martins Paiva EM Research Laboratory on Human Aging - GeronLab, Internal Medicine Department, Faculty of Medical Sciences, Rio de Janeiro State University, Rio de Janeiro, - - 2013
Few studies have been published on the use of the Cambridge Cognitive Examination Test - Revised (CAMCOG-R) for cognitive assessment of low educational level older adults. The aim of the present study was to determine the accuracy of the Brazilian version of the CAMCOG-R (Br-CAMCOG-R) within a sample of low ...
Semião-Santos Saul José SJ - - 2013
We compared performance of a locally produced β-mercaptoethanol-modified promastigote antigen (β-ME-Ag) of an indigenous Leishmania infantum strain against that of a trypsinized (REF-Ag) Leismania donovani reference in the direct agglutination test (DAT) for detection of canine visceral leishmaniasis (CVL). One hundred and fifty-one serum samples collected from dogs belonging to ...
Kwak Jae - - 2013
The urinary odors are commonly perceived as unpleasant. While numerous studies have identified the volatile organic compounds (VOCs) released from urine, the odorants responsible for the urine odor are not well characterized. Furthermore, anecdotal reports suggest that the odor of aged urine is different from that of fresh urine. However, ...
Chang Yun Brenda - - 2013
Background. Human T-lymphotropic virus types 1 and 2 (HTLV-1 and -2) are prevalent at low-level among United States blood donors, but recent data on their prevalence is lacking.Methods. Data on all first-time blood donors in a large network of United States blood centers were examined during the period 2000-2009. HTLV-1 and -2 ...
Wang Zhenxing - - 2013
A novel chemiluminescence resonance energy transfer (CRET) system for competitive immunoassay of biomolecules was developed by using novel amorphous carbon nanoparticles (CNPs) prepared from candle soot as energy acceptors. The CNPs were firstly prepared to bind with the antigen (Ag) for obtaining the nanocomposite CNP-Ag, and this obtained CNP-Ag was ...
van Lier Alies - - 2013
To date, there is no universal varicella vaccination in the Netherlands. We studied the seroprevalence of varicella zoster virus (VZV) specific antibodies and determinants for seropositivity among participants of a serosurveillance study, conducted in 2006/2007 among Dutch inhabitants 0-79 years of age. Materials and methods Serological testing of 6386 blood ...
Alonso-Bouzón Cristina - - 2013
Cardiovascular disease (CVD), both clinical and subclinical, has been proposed as one of the mechanisms underlying frailty. However, there is no evidence addressing the relationship between the earliest stage of CVD (endothelial dysfunction) and frailty. The goal of the study was to analyze the association between endothelial dysfunction, evaluated by ...
Afegbua Seniyat Larai - - 2013
Hepatitis A is an infectious viral disease, caused by hepatitis A virus (HAV), endemic in many developing countries. A recent review of the global prevalence of HAV infection and susceptibility by the WHO had few data on the seroprevalence of HAV in Nigeria. This study was designed to determine the ...
Kwak Jae - - 2013
Mice release a variety of chemical signals, particularly through urine, which mediate social interactions and endocrine function. Studies have been conducted to investigate the stability of urinary chemosignals in mice. Neuroendocrine and behavioral responses of mice to urine samples of male and female conspecifics which have aged for different amounts ...
Saghiri Mohammad Ali - - 2013
This study aims to evaluate the correlation between the presences of separated endodontic instrument inside the dental canal and the nickel (Ni) level in the urine samples of subjected patients. Same-gendered and near-aged participants were selected and were instructed to collect their urine in sterile nickel-free plastic containers. The procedures ...
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