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Salomone Alberto A Centro Regionale Antidoping e di Tossicologia 'A. Bertinaria', Regione Gonzole 10/1, 10043, Orbassano, Torino, - - 2014
Ethyl glucuronide in hair (HEtG) is the most accredited marker to prove chronic alcohol abuse. In this study, we evaluate the comprehensive results of HEtG determination obtained during four years of activity (2009-2013) in our laboratory (Northwestern Italy) - across a large cohort of subjects (over 20 000 subjects mostly ...
Chen Chi-Hsien CH Department of Environmental and Occupational Medicine, National Taiwan University Hospital, Taipei, - - 2014
Although styrene has been reported to cause colour vision impairment, the results were still inconclusive. Whether the impairment was related to short-term or long-term exposure was not known. The study aims to evaluate colour vision in high styrene exposed fibreglass-reinforced plastics (FRP) laminators. Fifty workers from two yacht factories participated, ...
Kaufman Alan S AS Yale University School of Medicine, New Haven, CT, USA. Electronic address: - - 2014
The dramatic decrease in U.S. blood lead levels (BLLs) since the 1970s has been documented-however, the anticipated societal impact on intelligence quotient (IQ) has not. The objectives of this study were to determine whether mean IQs of American adults, adjusted for demographics, have increased in concert with society׳s decreasing BLL. ...
Jurewicz Joanna - - 2013
Growing evidence supports the reproductive and developmental toxicity of polycyclic aromatic hydrocarbons (PAHs) from prenatal and postnatal exposure, but the results of epidemiological studies regarding harmful effects of PAHs exposure on male reproductive system still remain limited and inconclusive. The aim of the present study was to investigate the relationship ...
Kumar M Sudeepa S Assistant Professor, Department of Microbiology, Sri Siddhartha Medical College , Agalakote, Tumkur - 572107, Karnataka, India - - 2013
Enteric fever is an important public health problem in many underdeveloped and developing countries. In India, though Salmonella enterica serotype Typhi remains the predominant Salmonella species causing enteric fever, isolation of Salmonella enterica serotype Paratyphi A is increasing. It occurs in all age groups and more common in summer season ...
Wang Jiaqi - - 2013
Quantitative Salmonella concentrations and prevalence of Salmonella in raw chicken at the retail level in Shaanxi province, China, was determined in this study. Two hundred forty samples were collected in Yangling and the surrounding cities, in Shaanxi Province, China, for data collection over 12 successive months from April 2011 to ...
Muriel Jaime - - 2013
Yolk androgens in avian eggs play a significant role in embryo and nestling development. However, few studies have examined the differential effect of two of the main yolk androgens, testosterone (T) and androstenedione (A4). Here, we injected eggs of spotless starlings with physiological levels of either T, A4, the combination ...
Benowitz-Fredericks Z Morgan - - 2013
In birds, causes and consequences of variation in maternally-derived steroids in egg yolk have been the subject of intense experimentation. Many studies have quantified or manipulated testosterone ("T") and one of its immediate precursors, androstenedione ("A4") - often lumping the two steroids as "androgens" and treating them as functionally equivalent. ...
Szymanowicz Agata A YSC, London, - - 2013
This study examined participant gender and gender role differences in estimates of multiple intelligences for self, partner, and various hypothetical, stereotypical, and counter-stereotypical target persons. A general population sample of 261 British participants completed one of four questionnaires that required them to estimate their own and others' multiple intelligences and ...
Moore Nigel P - - 2013
The National Toxicology Program (NTP) database of technical reports on carcinogenicity bioassays has been interrogated for the incidence of primary pulmonary neoplasms in B6C3F1 mice. A total of 170 study reports were selected, from studies that completed the in-life phase during 1983-2007, which included neoplasm incidence data for 180 control ...
Scinicariello Franco F Division of Toxicology and Human Health Sciences, Agency for Toxic Substances and Disease Registry (ATSDR), Atlanta, Georgia, - - 2013
Polycyclic aromatic hydrocarbons (PAHs) are known carcinogens and suspected endocrine disruptors. Prenatal exposure to PAHs has been associated with obesity in early childhood. We examined the association of urinary PAH metabolites with adiposity outcomes (BMI z-score, waist circumference, and rate of obesity) in children and adolescents. We performed whole-sample analyses ...
Chaudhary Ketul R KR Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, AB, - - 2013
Cardioprotective effects of epoxyeicosatrienoic acids (EETs) have been demonstrated in models of young mice with either the cardiomyocyte specific over-expression of cytochrome P450 2J2 (CYP2J2 Tr) or deletion of soluble epoxide hydrolase (sEH null). In this study we examined differences in EET-induced cardioprotection in young (2 months) and aged (12 ...
Misra D P DP 1Department of Family Medicine, Wayne State University, Detroit, MI, - - 2012
We hypothesized that placental villous branching that is measured by disk chorionic plate expansion and disk thickness is correlated with factors also involved in regulation of branching growth of other fetal viscera (e.g. lung, kidney) including neuronal dendrites, and thus may be associated with variation in childhood intelligence quotient (IQ). ...
Koh Victor - - 2012
To describe the prevalence of epiretinal membrane (ERM) and its risk factors in an Indian population and compare the findings with other populations. The Singapore Indian Eye Study is a population-based survey of 3400 Asian Indians aged between 40 and 80 years. A comprehensive ophthalmic examination, standardized interviews, and laboratory ...
Leung Christopher K S - - 2012
OBJECTIVE: To investigate age-related changes of the retinal nerve fiber layer (RNFL) imaged by a spectral-domain optical coherence tomography (OCT). DESIGN: Prospective, cross-sectional, and longitudinal studies. PARTICIPANTS: One hundred normal individuals were recruited for cross-sectional analysis, 35 of whom were randomly selected for longitudinal analysis. METHODS: The circumpapillary average and ...
Pölkki Mari - - 2012
In many species of animals, individuals advertise their quality with sexual signals to obtain mates. Chemical signals such as volatile pheromones are species specific, and their primary purpose is to influence mate choice by carrying information about the phenotypic and genetic quality of the sender. The deleterious effects of consanguineous ...
Tremblay Marie-Ève MÈ Department of Neurobiology and Anatomy and Center for Visual Science, University of Rochester, Rochester, New York 14642, - - 2012
Normal aging is often accompanied by a progressive loss of receptor sensitivity in hearing and vision, whose consequences on cellular function in cortical sensory areas have remained largely unknown. By examining the primary auditory (A1) and visual (V1) cortices in two inbred strains of mice undergoing either age-related loss of ...
Clark David L - - 2012
Eavesdropping on communication is widespread among animals, e.g. bystanders observing male-male contests, female mate choice copying and predator detection of prey cues. Some animals also exhibit signal matching, e.g. overlapping of competitors' acoustic signals in aggressive interactions. Fewer studies have examined male eavesdropping on conspecific courtship, although males could increase ...
Kong Yu Xiang George - - 2012
Advancing age is a major risk factor for many neurodegenerative diseases but the underlying pathophysiology is not clear. We hypothesize that aging impairs the ability of neurons in the central nervous system to recover functionally after injury. To test this in retinal ganglion cells in vivo, we developed an optic ...
Falgreen Eriksen Hanne-Lise - - 2012
The aim of the study was to examine the effects of tobacco smoking in pregnancy on children's IQ at the age of 5. A prospective follow-up study was conducted on 1,782 women, and their offspring were sampled from the Danish National Birth Cohort. At 5 years of age, the children ...
Chartier Karen G - - 2012
Despite the growing number of interethnic marriages in the United States, few studies have examined intimate partner violence (IPV) in interethnic couples. This article examined past-year occurrences of IPV across interethnic and intraethnic couples and tested correlates of IPV specifically in interethnic couples. Data were from a national survey of ...
Urbanski Henryk F - - 2012
Many environmental conditions show rhythmic changes across the 24-h day; these include changes in light intensity, ambient temperature, food availability, and presence or absence of predators. Consequently, many organisms have developed corresponding adaptations, which ensure that specific physiological and behavioral events occur at an appropriate time of the day. In ...
Chen Hui - - 2011
Purpose: The aim of this study was to assess the changes in the prevalence of visual impairment due to blinding trachoma in Sichuan, China between 1987 and 2006. Methods: Over 125,000 residents of Sichuan province participated in the National Sample Survey on Disabilities, conducted in both 1987 and 2006. Changes ...
Ahmad Raise - - 2011
Abstract: Age dependent declining level of melatonin induces free radical load thereby deteriorates immune function. However, reports are lacking about age dependent melatonin membrane receptor (MT1 & MT2) expression, their role in regulation of reactive nitrogen species (RNS) and eventually how they affect immunity of a tropical rodent F. pennanti. ...
Choi Jaekyung - - 2011
Purpose: To evaluate the association between chronic kidney disease (CKD) and early age-related macular degeneration (AMD) and peripheral retinal drusen in Korean adults 50 years and older. Methods: This study included 3008 participants aged 50-87 years. Early AMD was assessed from retinal photographs based on modified Wisconsin AMD grading system ...
Deere Kerry A - - 2012
We tested the hypothesis that mate choice is responsible for countergradient variation in the sexual coloration of Trinidadian guppies (Poecilia reticulata). The nature of the countergradient pattern is that geographical variation in the carotenoid content of the orange spots of males is counterbalanced by genetic variation in drosopterin production, resulting ...
Tedore Cynthia - - 2011
Weaponry and color badges are commonly theorized to function as visual signals of aggressiveness or fighting ability. However, few studies have supported a signaling function of weaponry, and the role of color in invertebrate competitive interactions remains virtually unexplored. Jumping spiders (Salticidae) make excellent invertebrate models for studying weaponry and ...
Glenn J V JV School of Medicine, Dentistry and Biomedical Science, Queen's University Belfast, Northern Ireland, - - 2012
The retinal pigment epithelium (RPE) and underlying Bruch's membrane undergo significant modulation during ageing. Progressive, age-related modifications of lipids and proteins by advanced glycation end products (AGEs) at this cell-substrate interface have been implicated in RPE dysfunction and the progression to age-related macular degeneration (AMD). The pathogenic nature of these ...
Lumeng Carey N CN Department of Pediatrics and Communicable Diseases, University of Michigan, Ann Arbor, MI 48109, - - 2011
Age-related adiposity has been linked to chronic inflammatory diseases in late life. To date, the studies on adipose tissue leukocytes and aging have not taken into account the heterogeneity of adipose tissue macrophages (ATMs), nor have they examined how age impacts other leukocytes such as T cells in fat. Therefore, ...
Nieves-Martinez Erasmo - - 2012
Behavioral flexibility, the ability to modify responses due to changing task demands, is detrimentally affected by aging with a shift towards increased cognitive rigidity. The neurobiological basis of this cognitive deficit is not clear although striatal cholinergic neurotransmission has been implicated. To investigate the possible association between striatal acetylcholine signaling ...
Richer Stuart P - - 2011
The purpose of this study is to evaluate whether dietary supplementation with the carotenoid zeaxanthin (Zx) raises macula pigment optical density (MPOD) and has unique visual benefits for patients with early atrophic macular degeneration having visual symptoms but lower-risk National Institute of Health/National Eye Institute/Age-Related Eye Disease Study characteristics. This ...
Song Yang - - 2012
Increased circulating cytokine levels are a prominent feature of aging that may contribute to atherosclerosis. However, the role vascular cells play in chronic inflammation induced by aging is not clear. Here, we examined the role of aging on inflammatory responses of vascular cells. In an ex vivo culture system, we ...
Commo S - - 2011
Hair pigmentation is one of the most conspicuous phenotypes of humans. From a chemical point of view, however, data remain scarce regarding human hair pigmentation characteristics. To determine melanin content and composition in human eumelanic hair from individuals of different ethnic origins and at different ages, we collected hair from ...
Bittner A K AK Johns Hopkins University; Wilmer Eye Institute, Baltimore, MD 21205, USA. - - 2012
We measured the relationship between the occurrence of photopsias (spontaneous phosphenes), and retinitis pigmentosa (RP) subjects' level of vision, light exposure, and psychosocial factors to attempt to confirm RP patients' previous reports of these associations. A total of 36 RP subjects self-administered PC-based binocular visual acuity, contrast sensitivity, and visual ...
Martínez-Martínez Maria L - - 2011
  Progressive macular hypomelanosis (PMH) is a condition of unknown etiology characterized by asymptomatic, hypopigmented macules located predominantly on the trunk. We recorded 12 adolescents with PMH over a 6-month period. Ten were female, and the mean age was 16.6 years. The average time from the patients first noticing pigment change ...
Laliberté Alex M - - 2011
Current animal models of retinal disease often involve the rapid development of a retinal disease phenotype; however, this is at odds with age-related diseases that take many years to manifest clinical symptoms. The present study was performed to examine an Apoptosis-inducingfactor (Aif)-deficient model, the harlequin carrier mouse (X(hq)X), and determine ...
Thavarajah D - - 2011
IntroductionStudies on the ageing of bruises have been reported on Caucasians or individuals of fair ethnicity. This study focuses on bruise changes in dark-skinned individuals using tristimulus colorimetry for forensic analysis in such individuals.MethodsEighteen subjects of South Indian or Sri-Lankan ethnicity were recruited. Subjects were bruised using a vacuum pump ...
Seifert Ashley W - - 2011
One of the most compelling questions in evolutionary biology is why some animals can regenerate injured structures while others cannot. Appendage regeneration appears to be common when viewed across the metazoan phylogeny, yet this ability has been lost in many taxa to varying degrees. Within species, the capacity for regeneration ...
Girkin Christopher A - - 2011
PURPOSE: To evaluate the effects of age and race on optic disc, retinal nerve fiber layer, and macular measurements with spectral-domain optical coherence tomography (SD OCT). DESIGN: Cross-sectional observational study. PARTICIPANTS: Three hundred fifty adult subjects without ocular disease. METHODS: Data from SD OCT imaging of the optic nerve head, ...
Capparelli Mariana V - - 2011
Precocious maturity is an important life history trait and might be advantageous if the juvenile habitat is risky. Larvae of the mottled shore crab Pachygrapsus transversus settle to the benthic habitat at a very large size, undergo a brief juvenile development and mature within a few months at a size ...
Song Hongxin - - 2011
To study the variation of cone photoreceptor packing density across the retina in healthy subjects of different ages. High-resolution adaptive optics scanning laser ophthalmoscope (AOSLO) systems were used to systematically image the retinas of two groups of subjects of different ages. Ten younger subjects (age range, 22-35 years) and 10 ...
Chen Ellen W - - 2011
Good balance, an important ability in controlling body movement, declines with age. Also, balance appears to decrease when visual input is restricted, while this has been poorly investigated among visually impaired very old adults. The objective of this study is thus to explore whether the balance control of the very ...
Wood Ashley - - 2011
PURPOSE: To compare retinal thickness and choroidal thickness at increasing retinal eccentricity in individuals with early age-related macular degeneration (AMD) and in healthy controls using enhanced choroidal penetration, 3-dimensional optical coherence tomography at 1060 nm. DESIGN: Cross-sectional study. METHODS: Individuals with early AMD (n = 16; mean age, 71.6 ± ...
Huixia Q - - 2011
The pigmentation patterns of facial skin of 354 healthy Chinese women aged 18-80 years were investigated clinically and instrumentally. Chromasphere(®) was used to acquire pictures from the cheeks of subjects. Facial skin tone was described by L* parameter from the L,a,b system as well as Individual Typology Angle (ITA). Results show ...
Moses-Kolko Eydie L - - 2011
There is a need for rigorous positron emission tomography (PET) and endocrine methods to address inconsistencies in the literature regarding age, sex, and reproductive hormone effects on central serotonin (5HT) 1A and 2A receptor binding potential (BP). Healthy subjects (n=71), aged 20-80 years, underwent 5HT1A and 2A receptor imaging using ...
Garratt M - - 2011
Sexual signals are expected to be costly to produce and maintain, thus ensuring that only males in good condition can sustain their expression at high levels. When males reach senescence they lose physiological function and condition, which could constrain their ability to invest in costly sexual signals, decreasing their attractiveness ...
Uppal Gurmit - - 2011
PURPOSE. Macular translocation (MT360) is complex surgery used to restore reading in exudative age-related macular degeneration (AMD). MT360 involves retinal rotation and subsequent oculomotor globe counterrotation and is not without significant surgical risk. This study attempts to gauge the optimal potential of MT360 in restoring reading ability and describe the ...
Zhao Jianhua - - 2011
Obesity is a serious health concern for children and adolescents, particularly in Western societies, where its incidence is now considered to have reached epidemic proportions. A number of genetic determinants of adult BMI have already been established through genome wide association studies (GWAS), most recently from the GIANT meta-analysis of ...
Singh Pallavi - - 2011
Our previous study on immune-related changes in the aged liver described immune cell infiltration and elevation of inflammation with age. Levels of interferon (IFN)-γ, a known cell cycle inhibitor, were elevated in the aging liver. Here, we determine the role played by IFN-γ in the delayed regenerative response observed in ...
Bajer Katalin - - 2011
Animal communication through colour signals is a central theme in sexual selection. Structural colours can be just as costly and honest signals as pigment-based colours. Ultraviolet (UV) is a structural colour that can be important both in intrasexual competition and mate choice. However, it is still unknown if a UV ...
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