Search Results
Results 1 - 50 of 1531
1 2 3 4 5 6 7 8 9 10 >
Silva Silvana Marques E SM Coloproctology Service, University Hospital of Brasília, Brasília University, Brasília, DF, - - 2014
Colorectal cancer is a major cause of morbidity and mortality and can arise through the adenoma-carcinoma sequence. Colonoscopy is considered the method of choice for population-wide cancer screening. To assess the characteristics of endoscopically resected polyps in a consecutive series of patients who underwent colonoscopy at a university hospital and ...
Vichot Alfred A AA Department of Medicine, Yale University School of Medicine, New Haven, - - 2014
High anion gap (AG) metabolic acidosis, a common laboratory abnormality encountered in clinical practice, frequently is due to accumulation of organic acids such as lactic acid, keto acids, alcohol metabolites, and reduced kidney function. The cause of high AG metabolic acidosis often is established easily using historical and simple laboratory ...
Chung Shiu-Dong SD Sleep Research Center, Taipei Medical University, Taipei, - - 2014
Anxiety disorder (AD) is commonly associated with a number of physical illnesses. No previous study has investigated the association between AD and sudden sensorineural hearing loss (SSNHL). In this study, we investigated the association between prior AD and SSNHL using a population-based dataset in Taiwan. Sampled subjects of this case-control ...
Vos Byrthe J P R BJ Department of Allergology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands; GRIAC Research Institute, University of Groningen, University Medical Center Groningen, Groningen, The - - 2014
Currently, measurement of serum tryptase level is the most commonly used test to estimate the need for bone marrow biopsy in patients suspected to have indolent systemic mastocytosis (ISM). Yet tryptase levels do not solely reflect the mast cell load and can be elevated by overweight, older age, and impaired ...
Hirani Vasant V Centre for Education and Research on Ageing, University of Sydney, Sydney, New South Wales, Australia; School of Public Health, University of Sydney, Sydney, New South Wales, Australia; ARC Centre of Excellence in Population Ageing Research, University of Sydney, Sydney, New South Wales, - - 2014
To examine the associations between serum 25-hydroxyvitamin D (25OHD) levels and the active vitamin D metabolite, 1,25-hydroxyvitamin D (1,25OHD), with type 2 diabetes mellitus (DM) in community-living men aged 70 and older. Cross-sectional. A population-based, cross-sectional analysis of the baseline phase of the Concord Health and Ageing in Men Project ...
Bullens Dominique Ma DM Department of Immunology and Microbiology, K.U.Leuven, Leuven, Belgium; Clinical Department of Pediatrics, University Hospital UZ Leuven, Leuven, - - 2014
Data from birth cohort studies suggest that increased cord blood total IgE and reduced cord blood regulatory T cells increase the risk of developing allergic sensitization and atopic dermatitis. We here addressed whether serum total IgE and hen's egg specific IgE levels at birth and at age one year differed ...
Tran An Hong AH Department of Internal Medicine, Kaiser Permanente Los Angeles Medical Center, Los Angeles, - - 2014
The risks and benefits of surveillance colonoscopy in elderly patients have not been well characterized. To investigate the relative impact of surveillance colonoscopy in elderly patients compared with a reference cohort. Retrospective cohort study from 2001 through 2010 of patients 50 years and older undergoing surveillance colonoscopy for a history ...
Lam Thuy T Environmental and Occupational Medicine and Epidemiology Program, Department of Environmental Health, Harvard School of Public Health, Boston, MA, USA; Quintiles, Cambridge, MA, - - 2014
In animal studies, organochlorine pesticide (OCP) exposure alters pubertal development; however, epidemiological data are limited and inconsistent. To evaluate the associations of serum OCP concentrations [hexachlorobenzene (HCB), β-hexachlorocyclohexane (β-HCH), and p,p'-dichlorodiphenyldichloroethylene (p,p'-DDE)] with male pubertal onset. In Chapaevsk, Russia, a town environmentally contaminated with OCPs, 350 8-9year old boys with ...
Zhang Yan-Hua YH 1Department of Anesthesiology, Xuanwu Hospital of Capital Medical University , Beijing, 100053 , - - 2014
Purpose Postoperative cognitive dysfunction (POCD) characterized as the decline of memory and executive function after major surgery is not well illustrated. The aim of this study is to discover whether inflammatory cytokines and urinary trypsin inhibitor (uTi) contributes to the development of POCD. Method 63 patients undergoing lumber discectomy and ...
Thompson Cynthia - - 2014
Context/objective Traumatic spinal cord injuries (T-SCI) have a devastating impact and place a significant financial burden on the healthcare system. The incidence of T-SCI ranges from 10.4 to 83 cases per million and varies with age, sex, or geographical region. This study describes the epidemiology and demographic characteristics of patients ...
Maggio Marcello M Department of Clinical and Experimental Medicine, Section of Geriatrics, University of Parma, Italy Geriatric Rehabilitation Department, University Hospital of Parma, Parma, - - 2014
Objective. During the aging process in men testosterone (T) levels progressively fall and inflammatory biomarkers increase. Although a relationship between these two phenomena has been tested in previous clinical trials, there is inconclusive evidence about the potential anti-inflammatory action of T.Methods. A total of 108 healthy men >65 years with ...
Koch Marcus W MW Department of Clinical Neurosciences and Hotchkiss Brain Institute, University of Calgary, Calgary, Alberta, Canada Department of Community Health Sciences, University of Calgary, Calgary, Alberta, - - 2014
Primary progressive multiple sclerosis (PPMS) is the least common MS disease course and carries the worst prognosis. In relapsing-remitting multiple sclerosis (RRMS) disability accumulation occurs in two distinct phases, but it is unclear whether this is also true for PPMS. Here we investigate factors associated with early and late disability ...
Misterska Ewa E *Department of Pediatric Orthopaedics and Traumatology, Poznan University of Medical Sciences, Poland †Department of Human Developmental Psychology and Family Research, Institute of Psychology, Adam Mickiewicz University, Poland ‡Department of Paediatric Orthopaedics and Traumatology, SKN of Paediatric Orthopaedics and Traumatology; and §Department and Clinic of Surgery, Traumatology, and Pediatric Urology, Poznan University of Medical Sciences, - - 2014
A longitudinal pilot study of changes in levels of alexithymia among females with adolescent idiopathic scoliosis (AIS) under brace treatment. To investigate the prevalence of alexithymia and to evaluate changes in alexithymia levels among female patients with AIS treated with a Cheneau brace, in comparison with healthy female adolescents. Alexithymia ...
Tomialoic R R European Programme for Interventional Epidemiology Training (ECDC), European Centre for Disease Prevention and Control (ECDC), Stockholm, Sweden, - - 2014
Parapertussis leads to similar symptoms as pertussis, both being caused by bacteria from the genus Bordetella. Poland does not routinely diagnose nor conduct surveillance for parapertussis. We estimated parapertussis incidence and determined predictors of parapertussis diagnosis in the Polish population. Between July 2009 and April 2011, we conducted a prospective ...
Pavuk M M Agency for Toxic Substances and Disease Registry, Atlanta, GA, USA. Electronic address: - - 2014
The Anniston Community Health Survey was a community-based cross-sectional study of Anniston, Alabama, residents who live in close proximity to a former PCB production facility to identify factors associated with serum PCB levels. The survey comprises 765 Anniston residents who completed a questionnaire interview and provided a blood sample for ...
Seki Tatsuya T Department of Cardiovascular and Thoracic Surgery, Hokkaido University Graduate School of Medicine, Sapporo, Hokkaido, - - 2014
Purpose: Transcatheter aortic valve replacement (TAVR) has emerged as a therapeutic option for severe aortic valvular stenosis (AS). To determine the indication for TAVR, it is mandatory to clarify the characteristics of the patients who were judged as inoperable for conventional aortic valve replacement (cAVR).Methods: Of 185 patients newly diagnosed ...
Chularojanamontri Leena L Department of Dermatology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, - - 2014
There is a paucity of data regarding clinical differences between early-onset psoriasis (EOP) and late-onset psoriasis (LOP) in Asian populations. This study aimed to investigate clinical differences between EOP (onset at the age of <40 years) and LOP (onset at the age of ≥40 years) in Thai patients. From 2002 until 2008, ...
Al-Daghri Nasser M NM Biomarkers Research Program, Biochemistry Department, College of Science, ‡Prince Mutaib Chair for Biomarkers of Osteoporosis, Biochemistry Department, College of Science, §Center of Excellence in Biotechnology Research, and #Department of Clinical Pharmacy, College of Pharmacy, King Saud University , Riyadh 12372, Kingdom of Saudi - - 2014
Linking gender-specific differences to the molecular etiology of obesity has been largely based on genomic and transcriptomic evidence lacking endophenotypic insight and is not applicable to the extracellular fluid compartments, or the milieu intérieur, of the human body. To address this need, this study profiled the whole serum proteomes of ...
Stagi S S Health Sciences Department, University of Florence, Anna Meyer Children's University Hospital, Florence, - - 2014
Few prospective data have been published on the comparison of bone density and quality in homogeneous groups of patients with juvenile systemic lupus erythematosus (JSLE) and juvenile idiopathic arthritis (JIA). The objective of this study is to perform a longitudinal evaluation of the prevalence and the characteristics of bone mass ...
Cunha F S FS Unidade de Endocrinologia do Desenvolvimento, Laboratório de Hormônios e Genética Molecular LIM42, Disciplina de Endocrinologia, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, SP, - - 2014
Male-to-female transsexual persons use oestrogens + antiandrogens to adapt their physical bodies to the female sex. Doses are usually somewhat higher than those used by hypogonadal women receiving oestrogen replacement. Particularly in cases of self-adminstration of cross-sex hormones, doses may be very high. Oestrogens are powerful stimulators of synthesis and release of ...
Obayashi Kenji K Department of Community Health and Epidemiology, Nara Medical University School of Medicine, Nara, - - 2014
To evaluate the relationship between asymmetric dimethylarginine (ADMA) and nocturia. A total of 862 community-based elderly individuals were examined in this cross-sectional study (mean age, 72.1 years). We measured nocturnal void frequency and serum ADMA levels. Nocturia was ascertained for a frequency of two or more nocturnal voids. Nocturia was ...
Ring Margareta M 1] Section of Clinical Physiology, Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden [2] Department of Clinical Physiology, Karolinska University Hospital, Karolinska University Hospital, Stockholm, - - 2014
Arterial stiffness is an important cardiovascular risk marker, which can be measured noninvasively with different techniques. To validate such techniques in healthy subjects, we compared the recently introduced oscillometric Arteriograph (AG) technique with the tonometric SphygmoCor (SC) method and their associations with carotid ultrasound measures and traditional risk indicators. Sixty-three ...
Pinola P P Department of Obstetrics and Gynaecology, Oulu University Hospital, University of Oulu and Medical Research Center Oulu, Oulu, - - 2014
Can serum anti-Müllerian hormone (AMH) levels measured in female adolescents predict polycystic ovary syndrome (PCOS)-associated features in adolescence and early adulthood? AMH levels associated well with PCOS-associated features (such as testosterone levels and oligoamenorrhoea) in adolescence, but was not an ideal marker to predict PCOS-associated features in early adulthood. Several ...
Porsbjerg C C Respiratosry Research Unit, Department of Respiratory Medicine, Bispebjerg University Hospital, Copenhagen, Denmark. Electronic address: - - 2014
Late onset asthma is associated with more severe disease and higher morbidity than in younger asthma patients. This may in part relate to under recognition of asthma in older adults, but evidence on the impact of patient age on diagnostic assessment of asthma in a specialist setting is sparse. To ...
Tartof Sara Y SY Department of Research and Evaluation, Kaiser Permanente Southern California, Pasadena. Electronic address: - - 2014
To describe incidence rates (IRs) of polymerase chain reaction (PCR)-diagnosed Clostridium difficile infection (CDI) in a large high-risk cohort. Members of Kaiser Permanente Southern California 1 year or older who were admitted to any of 14 Kaiser Permanente hospitals from January 1, 2011, through December 31, 2012, were included in ...
- - 2014
An estimated 1.3 million people over the age of 65 are believed to be malnourished in the UK.
Graffe Alix A Ophthalmology, Angers University Hospital, Angers, 49933, - - 2014
Purpose. Vitamin D insufficiency is associated with age-related macular degeneration. Our objective was to determine whether low serum 25-hydroxyvitamin D (25OHD) concentration was associated with macular thickness among older adults with no signs of macular dysfunction. Methods. Sixty-two French older community-dwellers with no patent macular dysfunction (mean±standard deviation, 71.2±5.0years; 45.2% ...
Messedi Emna E Microbiology Department, Habib Bourguiba Hospital/Faculty of Medicine, South University, Sfax, - - 2014
A large and unusually prolonged rubella outbreak occurred in Tunisia from April 2011 to July 2012 and was characterized by a high number of neurological cases. To describe the outbreak and to perform virus genotyping of isolated virus strains. From January 2011 to December 2012, 5000 sera for serological diagnosis ...
Kiuru Eveliina E Department of Surgery, Kuopio University Hospital and School of Medicine, University of Eastern Finland, Kuopio, - - 2014
Background: The impact of the age and sex adjusted body mass index (ISO-BMI) in the obese vs. non-obese children and adolescents with cholecystectomy for cholelithias is rarely reported. Patients and Methods: The national database was searched for cholecystectomies performed in paediatric patients between 1997 and 2011, and the 59 paediatric ...
Kitano Naomi N Department of Public Health, School of Medicine, Wakayama Medical - - 2014
Background: To clarify the contribution of patient age to the development of coronary artery lesions (CALs) associated with Kawasaki disease (KD), epidemiologic features and prognostic factors were investigated using hospital-based complete enumeration surveys in a specific area.Methods: Consecutive KD cases identified between October 1999 and September 2012 in Wakayama Prefecture, ...
Forbes Michael M Department of Pediatrics; Akron Children's Hospital; Akron, OH - - 2014
Monthly doses of palivizumab, an RSV-specific monoclonal antibody, reduce RSV-related hospitalizations (RSVH) in high-risk children; however, no specific palivizumab level has been correlated with disease severity in humans. A post hoc analysis of a previous randomized, placebo-controlled trial evaluated the relationship between serum palivizumab level at the time of RSVH ...
Kessler Jeffrey I JI Kaiser Permanente Southern California, Los Angeles, California, USA - - 2014
Osteochondritis dissecans (OCD) of the ankle is a disorder of the talar or distal tibial subchondral bone and articular cartilage whose incidence in children is not clearly known. To assess the demographics and epidemiology of OCD of the ankle in children. Descriptive epidemiologic study. A retrospective chart review of an ...
Cicero Arrigo Francesco Giuseppe AF Medical and Surgical Sciences Department, University of Bologna, Bologna, Italy, - - 2014
Contrasting evidence shows a possible association between serum uric acid (SUA) and cognitive function in elderly subjects. We aimed at evaluating the impact of circulating SUA levels on cognitive function in a cohort of pharmacologically untreated young elderly subjects. For this study, we selected 288 healthy young elderly participants from ...
Xie Liang L Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China; Institute of Neuroscience, Chongqing Medical University, Chongqing, China; Chongqing Key Laboratory of Neurobiology, Chongqing, - - 2014
The cynomolgus monkey (Macaca fascicularis) has been increasingly used in biomedical research. Although living conditions affect behavioral and physiological characteristics in macaques, little data is available on how living conditions influence blood-based parameters in the cynomolgus monkey. We hypothesize that there are significant differences in serum biochemical and hematological parameters ...
Herrick Kirsten A - - 2014
Data from the National Health and Nutrition Examination Survey (NHANES) and the NHANES National Youth Fitness Survey, 2012. Nearly all (98.5%) youth aged 12-15 reported watching TV daily. More than 9 in 10 (91.1%) youth aged 12-15 reported using the computer daily outside of school. In 2012, 27.0% of youth ...
Mustafa Mahmoud M Urology Department, School of Medicine and Health Science, An-Najah University, Nablus, West-Bank, - - 2014
To evaluate the relationship between levels of total testosterone and total prostate-specific antigen (PSA) in healthy men with PSA<4 ng/mL. The study comprised 179 men with a mean age of 59.19±12 years who visited Osmaniye State Hospital, Osmaniye, Turkey, between January 2006 and January 2007 for a routine checkup. The ...
Anupama Y J YJ Department of Nephrology, Nanjappa Hospital, Shimoga, Karnataka, - - 2014
Prevalence of chronic kidney disease (CKD) appears to be increasing in India. A few studies have studied the prevalence of CKD in urban populations, but there is a paucity of such studies in the rural populations. This project was undertaken to study the prevalence of CKD among adults in a ...
Saad Farid F Bayer Pharma, Global Medical Affairs Andrology, Berlin, Germany; Gulf Medical University School of Medicine, Ajman, UAE. Electronic address: - - 2014
Some men between the ages 45 and 60 years develop complaints and symptoms reminiscent of menopausal complaints in women. So, parallels were sought between the changes in female and male endocrinology during that period of life. Indeed, men do show a decline of serum testosterone from age 40 to 50 ...
Toms L-M L LM School of Clinical Sciences and Institute for Health and Biomedical Innovation, Queensland University of Technology, Gardens Point, Brisbane 4001, Australia. Electronic address: - - 2014
Some perfluoroalkyl and polyfluoroalkyl substances (PFASs) have become widespread pollutants detected in human and wildlife samples worldwide. The main objective of this study was to assess temporal trends of PFAS concentrations in human blood in Australia over the last decade (2002-2011), taking into consideration age and sex trends. Pooled human ...
Søeborg Tue T Department of Growth and Reproduction, Rigshospitalet, Copenhagen University Hospital, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark. Electronic address: - - 2014
The influence of sex, age, pubertal development and oral contraceptives on dehydroepiandrosterone (DHEA), DHEA sulfate (DHEAS), 17α-hydroxyprogesterone (17-OHP), Δ4-androstenedione (Adione), testosterone (T), calculated free testosterone (fT), free androgen index (FAI) and selected ratios in 1798 serum samples from healthy children, adolescents and young adults was evaluated. Samples were analyzed by ...
Chen Ning-Yuan - - 2014
Variants in Methylenetetrahydrofolate reductase (MTHFR) gene may result in a lowered catalytic activity and associate with subsequent elevated serum homocysteine (Hcy) concentration, abnormal DNA synthesis and methylation, cardiovascular risk, and unhealthy aging. Several investigations on the relationship of MTHFR C677T polymorphism with serum lipid profile and longevity have been conducted ...
Perna Laura L Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, - - 2014
Background/Aims: Very few studies have investigated the longitudinal association between serum levels of 25-hydroxyvitamin D [25(OH)D] and cognitive impairment not due to dementia. This longitudinal study analysed 25(OH)D and the risk of cognitive decline among non-demented older adults. Methods: A subsample of the ESTHER cohort study, aged ≥70 years, was ...
Rodriguez-Merchan Emerito Carlos EC Department of Orthopaedic Surgery, La Paz University Hospital, Paseo de la Castellana 261, 28046 Madrid, - - 2014
Radiosynovectomy (RS) is the best choice for patients with persistent synovitis of the knee unresponsive to a 3-month trial of prophylactic factor replacement. If three consecutive RSs with 6-month intervals have been ineffective, an arthroscopic synovectomy should be indicated in patients older than 12 years of age (adolescents). In children ...
Belsky Daniel W DW Duke University Medical Center, Center for the Study of Aging and Human Development , 2020 W Main St. , Suite 201 , Durham, North Carolina, United States, 27708 , 919-613-4534 ; - - 2014
Background. Asthma is prospectively associated with age-related chronic diseases and mortality, suggesting the hypothesis that asthma may relate to a general, multi-system phenotype of accelerated aging. Objective. To test whether chronic asthma is associated with a proposed biomarker of accelerated aging, leukocyte telomere length. Method. Asthma was ascertained prospectively in ...
Griffin Justin W JW Department of Orthopaedic Surgery, University of Virginia Health System, Charlottesville, VA, - - 2014
Elderly and young patients alike are undergoing shoulder replacement at increased rates. In an era of outcomes reporting, risk adjustment, and cost containment, identifying patients likely to have adverse events is increasingly important. Our objective was to determine whether patient age is independently associated with postoperative in-hospital complications or increased ...
Nakano Makiko - - 2014
Background:Dose-dependent adverse lung effects due to indium exposure have been reported in a cross-sectional study. This is a 5-year longitudinal cohort study of indium-exposed and unexposed workers, assessing indium exposure levels and its clinical lung effects. Methods:From 2008 to 2011, a 5-year follow-up study was conducted on 40 unexposed and ...
Cheng Daomei - - 2014
Objective An intervention study was performed to determine if supplement containing folic acid, vitamin B6, and vitamin B12 could improve cognitive function and lower homocysteine in middle-aged and elderly patients with hyperhomocysteinemia. Methods One hundred and four participants with hyperhomocysteinemia were recruited in Tianjin, China, aged 55-94 years old. Fifty-seven ...
Itty Sujit S *Department of Ophthalmology, Duke University Medical Center; †Department of Ophthalmology, Stanford Medical Center; ‡Department of Medicine, Duke University Medical Center; §Geriatric Research Education and Clinical Centers, Veterans Affairs Medical Center, Durham, North Carolina; ¶The Carolinas Center for Medical Excellence, Cary, North Carolina; and **Division of Biostatistics, Duke University Medical - - 2014
To compare 25-hydroxyvitamin D (25OHD) levels in patients with neovascular age-related macular degeneration (NVAMD) with patients with nonneovascular age-related macular degeneration and control patients. Medical records of all patients diagnosed with age-related macular degeneration and tested for serum 25OHD level at a single medical center were reviewed. Control patients were ...
WysokiƄski A A Department of Old Age Psychiatry and Psychotic Disorders, Medical University of Lodz, Lodz, - - 2014
Introduction: The present study was undertaken to determine if patients with schizophrenia on clozapine monotherapy have lower serum levels of peptide YY [PYY(1-36)], which is an endogenous inhibitor of food intake, comparing to healthy controls. Methods: Data for 24 patients (mean age 38.8 years) with paranoid schizophrenia on clozapine monotherapy ...
Klingberg Eva E From the Department of Rheumatology and Inflammation Research, Sahlgrenska Academy, University of Gothenburg, Sweden. Supported by grants from The Health and Medical Care Executive Board of the Västra Götaland, Rune and Ulla Amlövs foundation for Rheumatology Research, Göteborg's Association Against Rheumatism, The Medical Society of Göteborg, the Medical Society of Göteborg and the Region Västra Götaland (agreement concerning research and education of doctors), COMBINE, the Margareta Rheuma research foundation, and the Inger Bendix foundation. E. Klingberg, MD, PhD; M. Nurkkala, PhD; H. Carlsten, MD, PhD, Professor; H. Forsblad-d'Elia, MD, PhD, Associate professor, Department of Rheumatology and Inflammation Research, Sahlgrenska Academy at the University of Gothenburg. Address correspondence to Dr. E. Klingberg, Department of Rheumatology at Sahlgrenska/SU, Gröna stråket 14; S-413 45 Gothenburg, Sweden. E-mail: Eva.Klingberg@vgregion.se. Accepted for publication March 7, - - 2014
To identify biomarkers for bone metabolism in patients with ankylosing spondylitis (AS) and to determine the relationship between these biomarkers and disease activity, back mobility, osteoproliferation, and bone mineral density (BMD). Serum levels of Wingless protein (Wnt-3a), Dickkopf-1 (DKK-1), sclerostin, soluble receptor activator of nuclear factor-κΒ ligand (sRANKL), and osteoprotegerin ...
1 2 3 4 5 6 7 8 9 10 >