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Silva Silvana Marques E SM Coloproctology Service, University Hospital of Brasília, Brasília University, Brasília, DF, - - 2014
Colorectal cancer is a major cause of morbidity and mortality and can arise through the adenoma-carcinoma sequence. Colonoscopy is considered the method of choice for population-wide cancer screening. To assess the characteristics of endoscopically resected polyps in a consecutive series of patients who underwent colonoscopy at a university hospital and ...
Kosmidis M - - 2014
We explored driving patterns under conditions with and without driver distraction in a community sample of adults. We recruited 100 community-dwelling participants who were current drivers (65 men, healthy: n = 52, mild cognitive impairment [MCI]: n = 22, Alzheimer's disease [AD]: n = 8, Parkinson's disease [PD]: n = ...
Culnan E - - 2014
To examine the relationship between body mass index (BMI), and social cognitive measures of emotion in 8-19 year-olds. Participants from the Philadelphia Neurodevelopmental cohort (N = 2, 869; ages 8-19) were categorized by age (grouped in two-year increments) and BMI (normal 5th to < 85th percentile; overweight 85th to < ...
Zamzow J - - 2014
To examine the relationship between body mass index (BMI), and executive functioning in 8-19 year- olds. Participants from the Philadelphia Neurodevelopmental cohort (N = 2, 841; ages 8-19) were categorized by age (2 years) and BMI (i.e., normal weight [n = 1, 647], overweight [n = 510], and obese [n ...
Cook A - - 2014
Full recovery is typical among individuals with a single, uncomplicated concussion/mild traumatic brain injury (MTBI). Less is known about the long-term effects of multiple concussion/MTBI. This study aims to compare psychomotor speed and cognitive flexibility in patients with a history of multiple MTBI to those with a history of a ...
Ali A A Division of Psychiatry, University College London, London, - - 2014
Studies have shown that individuals with intellectual disability (ID) are aware of stigma and are able to describe experiences of being treated negatively. However, there have been no cross-cultural studies examining whether self-reported experiences of stigma vary between ethnic groups. Participants with mild and moderate ID were recruited from a ...
Squeglia Lindsay M LM Department of Psychiatry , University of California San Diego, San Diego, - - 2014
This review incorporates current research examining alcohol's differential effects on adolescents, adults, and aged populations in both animal and clinical models. The studies presented range from cognitive, behavioral, molecular, and neuroimaging techniques, leading to a more comprehensive understanding of how acute and chronic alcohol use affects the brain throughout the ...
Venuto Charles S CS Center for Human Experimental Therapeutics, University of Rochester, Rochester, NY, USA AIDS Clinical Trials Group Pharmacology Specialty Laboratory, New York State Center of Excellence in Bioinformatics and Life Sciences, School of Pharmacy and Pharmaceutical Sciences, University at Buffalo, Buffalo, NY, USA - - 2014
It is uncertain whether HIV-1 antiretroviral exposure and clinical response varies between males and females or different race/ethnic groups. We describe ritonavir-enhanced atazanavir pharmacokinetics in relation to virological failure, safety and tolerability in treatment-naive individuals to investigate potential differences. Plasma samples were collected from participants in AIDS Clinical Trials Group ...
Gonçalves Thaís Marques Simek Vega TM Post-doctoral student, Department of Prosthodontics and Periodontology, Piracicaba Dental School, University of Campinas, Piracicaba, São Paulo, - - 2014
An unfavorable denture-bearing area could compromise denture retention and stability, limit mastication, and possibly alter masticatory motion. The purpose of this study was to evaluate the masticatory movements of denture wearers with normal and resorbed denture-bearing areas. Completely edentulous participants who received new complete dentures were selected and divided into 2 ...
Ma Lina L Central Laboratory, Xuanwu Hospital of Capital Medical University, Key Laboratory for Neurodegenerative Disease of Ministry of Education, Center of Alzheimer's Disease, Beijing Institute for Brain Disorders, #45 Changchun Street, Xicheng District, Beijing 100053, China; Department of Geriatrics, Xuanwu Hospital of Capital Medical University, Beijing, - - 2014
Alzheimer-associated neuronal thread protein (AD7c-NTP) has been found to be a biomarker for Alzheimer's disease (AD) with elevated levels in the cerebrospinal fluid and urine from AD patients in the early stage of the disease. Whether the urine level of AD7c-NTP in healthy people is age-related is still unclear. We ...
Kenawey Mohamed M Department of Orthopaedic Surgery, Sohag University, Sohag 82524, Egypt. E-mail address: - - 2014
Pelvic osteotomies are frequently used as part of the surgical management of bladder exstrophy. The outcomes are often measured on the basis of the residual symphyseal diastasis. The aims of this study were to evaluate and validate a more reliable radiographic measure of ischiopubic rotation, to utilize this measure in ...
Han Su-Hyun SH Department of Neurology, Chung-Ang University College of Medicine, Seoul 156 755, Republic of - - 2014
We validated the use of medial temporal volume measurements via the automated volumetric method of Individual Brain Atlases using Statistical Parametric Mapping (IBASPM) in screening for Alzheimer's disease (AD). We also determined the optimal cut-off values for hippocampal volumes. This study included T1-weighted MRI of 89 patients with AD and ...
Vichot Alfred A AA Department of Medicine, Yale University School of Medicine, New Haven, - - 2014
High anion gap (AG) metabolic acidosis, a common laboratory abnormality encountered in clinical practice, frequently is due to accumulation of organic acids such as lactic acid, keto acids, alcohol metabolites, and reduced kidney function. The cause of high AG metabolic acidosis often is established easily using historical and simple laboratory ...
Chung Shiu-Dong SD Sleep Research Center, Taipei Medical University, Taipei, - - 2014
Anxiety disorder (AD) is commonly associated with a number of physical illnesses. No previous study has investigated the association between AD and sudden sensorineural hearing loss (SSNHL). In this study, we investigated the association between prior AD and SSNHL using a population-based dataset in Taiwan. Sampled subjects of this case-control ...
Vos Byrthe J P R BJ Department of Allergology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands; GRIAC Research Institute, University of Groningen, University Medical Center Groningen, Groningen, The - - 2014
Currently, measurement of serum tryptase level is the most commonly used test to estimate the need for bone marrow biopsy in patients suspected to have indolent systemic mastocytosis (ISM). Yet tryptase levels do not solely reflect the mast cell load and can be elevated by overweight, older age, and impaired ...
Hirani Vasant V Centre for Education and Research on Ageing, University of Sydney, Sydney, New South Wales, Australia; School of Public Health, University of Sydney, Sydney, New South Wales, Australia; ARC Centre of Excellence in Population Ageing Research, University of Sydney, Sydney, New South Wales, - - 2014
To examine the associations between serum 25-hydroxyvitamin D (25OHD) levels and the active vitamin D metabolite, 1,25-hydroxyvitamin D (1,25OHD), with type 2 diabetes mellitus (DM) in community-living men aged 70 and older. Cross-sectional. A population-based, cross-sectional analysis of the baseline phase of the Concord Health and Ageing in Men Project ...
Bullens Dominique Ma DM Department of Immunology and Microbiology, K.U.Leuven, Leuven, Belgium; Clinical Department of Pediatrics, University Hospital UZ Leuven, Leuven, - - 2014
Data from birth cohort studies suggest that increased cord blood total IgE and reduced cord blood regulatory T cells increase the risk of developing allergic sensitization and atopic dermatitis. We here addressed whether serum total IgE and hen's egg specific IgE levels at birth and at age one year differed ...
Tran An Hong AH Department of Internal Medicine, Kaiser Permanente Los Angeles Medical Center, Los Angeles, - - 2014
The risks and benefits of surveillance colonoscopy in elderly patients have not been well characterized. To investigate the relative impact of surveillance colonoscopy in elderly patients compared with a reference cohort. Retrospective cohort study from 2001 through 2010 of patients 50 years and older undergoing surveillance colonoscopy for a history ...
Lam Thuy T Environmental and Occupational Medicine and Epidemiology Program, Department of Environmental Health, Harvard School of Public Health, Boston, MA, USA; Quintiles, Cambridge, MA, - - 2014
In animal studies, organochlorine pesticide (OCP) exposure alters pubertal development; however, epidemiological data are limited and inconsistent. To evaluate the associations of serum OCP concentrations [hexachlorobenzene (HCB), β-hexachlorocyclohexane (β-HCH), and p,p'-dichlorodiphenyldichloroethylene (p,p'-DDE)] with male pubertal onset. In Chapaevsk, Russia, a town environmentally contaminated with OCPs, 350 8-9year old boys with ...
Nicholson Vaughan P VP School of Health and Sport Sciences, University of the Sunshine Coast, Queensland, Australia. Electronic address: - - 2014
To determine the effect of 26 weeks of low-load high-repetition resistance training (BodyPump™) on maximal strength, gait speed, balance and self-reported health status in healthy, active middle-aged and older adults. Two-group randomised control trial. Sixty-eight apparently healthy, active adults aged over 55 years completed either 26 weeks of BodyPump™ training ...
Zhang Yan-Hua YH 1Department of Anesthesiology, Xuanwu Hospital of Capital Medical University , Beijing, 100053 , - - 2014
Purpose Postoperative cognitive dysfunction (POCD) characterized as the decline of memory and executive function after major surgery is not well illustrated. The aim of this study is to discover whether inflammatory cytokines and urinary trypsin inhibitor (uTi) contributes to the development of POCD. Method 63 patients undergoing lumber discectomy and ...
Thompson Cynthia - - 2014
Context/objective Traumatic spinal cord injuries (T-SCI) have a devastating impact and place a significant financial burden on the healthcare system. The incidence of T-SCI ranges from 10.4 to 83 cases per million and varies with age, sex, or geographical region. This study describes the epidemiology and demographic characteristics of patients ...
Maggio Marcello M Department of Clinical and Experimental Medicine, Section of Geriatrics, University of Parma, Italy Geriatric Rehabilitation Department, University Hospital of Parma, Parma, - - 2014
Objective. During the aging process in men testosterone (T) levels progressively fall and inflammatory biomarkers increase. Although a relationship between these two phenomena has been tested in previous clinical trials, there is inconclusive evidence about the potential anti-inflammatory action of T.Methods. A total of 108 healthy men >65 years with ...
Koch Marcus W MW Department of Clinical Neurosciences and Hotchkiss Brain Institute, University of Calgary, Calgary, Alberta, Canada Department of Community Health Sciences, University of Calgary, Calgary, Alberta, - - 2014
Primary progressive multiple sclerosis (PPMS) is the least common MS disease course and carries the worst prognosis. In relapsing-remitting multiple sclerosis (RRMS) disability accumulation occurs in two distinct phases, but it is unclear whether this is also true for PPMS. Here we investigate factors associated with early and late disability ...
Misterska Ewa E *Department of Pediatric Orthopaedics and Traumatology, Poznan University of Medical Sciences, Poland †Department of Human Developmental Psychology and Family Research, Institute of Psychology, Adam Mickiewicz University, Poland ‡Department of Paediatric Orthopaedics and Traumatology, SKN of Paediatric Orthopaedics and Traumatology; and §Department and Clinic of Surgery, Traumatology, and Pediatric Urology, Poznan University of Medical Sciences, - - 2014
A longitudinal pilot study of changes in levels of alexithymia among females with adolescent idiopathic scoliosis (AIS) under brace treatment. To investigate the prevalence of alexithymia and to evaluate changes in alexithymia levels among female patients with AIS treated with a Cheneau brace, in comparison with healthy female adolescents. Alexithymia ...
Soto-Rey Javier J 1 Centre for Inclusive Sports Studies, Faculty of Physical Activity and Sport Sciences, Polytechnic University of Madrid, - - 2014
Summary.-This study analyzes the differences in manual reaction time (RT) to visual stimuli in two samples of physically active persons: a group of athletes without hearing impairment (n = 79; M age = 22.6 yr., SD = 3.7) and a group of athletes with hearing impairment (n = 44, M ...
Townsend Claire C Department of Native Hawaiian Health, John A Burns School of Medicine, University of Hawai'i at Manoa (CT, JYT-L, - - 2014
Often overlooked explanations for the varied obesity rates across ethno-cultural groups include differences in attitudes toward excess weight, with certain populations assumed to have larger ideal body sizes (IBS). Past studies found ethnic and gender difference in IBS across and within different groups. This study examined the effects of ethnicity ...
Wu Sheng-Hui SH Division of Epidemiology, Department of Medicine, Institute of Medicine and Public Health, Vanderbilt University Medical Center, Nashville, - - 2014
Alcohol consumption is influenced by heritable factors. The genetic influence on usual high-density drinking, including alcohol intoxication and hangover, is unknown. We aim to estimate the heritability of usual high-density drinking. A total of 13,511 male twins in this cross-sectional study were included from the National Academy of Sciences-National Research ...
Tomialoic R R European Programme for Interventional Epidemiology Training (ECDC), European Centre for Disease Prevention and Control (ECDC), Stockholm, Sweden, - - 2014
Parapertussis leads to similar symptoms as pertussis, both being caused by bacteria from the genus Bordetella. Poland does not routinely diagnose nor conduct surveillance for parapertussis. We estimated parapertussis incidence and determined predictors of parapertussis diagnosis in the Polish population. Between July 2009 and April 2011, we conducted a prospective ...
Pavuk M M Agency for Toxic Substances and Disease Registry, Atlanta, GA, USA. Electronic address: - - 2014
The Anniston Community Health Survey was a community-based cross-sectional study of Anniston, Alabama, residents who live in close proximity to a former PCB production facility to identify factors associated with serum PCB levels. The survey comprises 765 Anniston residents who completed a questionnaire interview and provided a blood sample for ...
Seki Tatsuya T Department of Cardiovascular and Thoracic Surgery, Hokkaido University Graduate School of Medicine, Sapporo, Hokkaido, - - 2014
Purpose: Transcatheter aortic valve replacement (TAVR) has emerged as a therapeutic option for severe aortic valvular stenosis (AS). To determine the indication for TAVR, it is mandatory to clarify the characteristics of the patients who were judged as inoperable for conventional aortic valve replacement (cAVR).Methods: Of 185 patients newly diagnosed ...
Chularojanamontri Leena L Department of Dermatology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, - - 2014
There is a paucity of data regarding clinical differences between early-onset psoriasis (EOP) and late-onset psoriasis (LOP) in Asian populations. This study aimed to investigate clinical differences between EOP (onset at the age of <40 years) and LOP (onset at the age of ≥40 years) in Thai patients. From 2002 until 2008, ...
Al-Daghri Nasser M NM Biomarkers Research Program, Biochemistry Department, College of Science, ‡Prince Mutaib Chair for Biomarkers of Osteoporosis, Biochemistry Department, College of Science, §Center of Excellence in Biotechnology Research, and #Department of Clinical Pharmacy, College of Pharmacy, King Saud University , Riyadh 12372, Kingdom of Saudi - - 2014
Linking gender-specific differences to the molecular etiology of obesity has been largely based on genomic and transcriptomic evidence lacking endophenotypic insight and is not applicable to the extracellular fluid compartments, or the milieu intérieur, of the human body. To address this need, this study profiled the whole serum proteomes of ...
Stagi S S Health Sciences Department, University of Florence, Anna Meyer Children's University Hospital, Florence, - - 2014
Few prospective data have been published on the comparison of bone density and quality in homogeneous groups of patients with juvenile systemic lupus erythematosus (JSLE) and juvenile idiopathic arthritis (JIA). The objective of this study is to perform a longitudinal evaluation of the prevalence and the characteristics of bone mass ...
Cunha F S FS Unidade de Endocrinologia do Desenvolvimento, Laboratório de Hormônios e Genética Molecular LIM42, Disciplina de Endocrinologia, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, SP, - - 2014
Male-to-female transsexual persons use oestrogens + antiandrogens to adapt their physical bodies to the female sex. Doses are usually somewhat higher than those used by hypogonadal women receiving oestrogen replacement. Particularly in cases of self-adminstration of cross-sex hormones, doses may be very high. Oestrogens are powerful stimulators of synthesis and release of ...
Obayashi Kenji K Department of Community Health and Epidemiology, Nara Medical University School of Medicine, Nara, - - 2014
To evaluate the relationship between asymmetric dimethylarginine (ADMA) and nocturia. A total of 862 community-based elderly individuals were examined in this cross-sectional study (mean age, 72.1 years). We measured nocturnal void frequency and serum ADMA levels. Nocturia was ascertained for a frequency of two or more nocturnal voids. Nocturia was ...
Ring Margareta M 1] Section of Clinical Physiology, Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden [2] Department of Clinical Physiology, Karolinska University Hospital, Karolinska University Hospital, Stockholm, - - 2014
Arterial stiffness is an important cardiovascular risk marker, which can be measured noninvasively with different techniques. To validate such techniques in healthy subjects, we compared the recently introduced oscillometric Arteriograph (AG) technique with the tonometric SphygmoCor (SC) method and their associations with carotid ultrasound measures and traditional risk indicators. Sixty-three ...
Pinola P P Department of Obstetrics and Gynaecology, Oulu University Hospital, University of Oulu and Medical Research Center Oulu, Oulu, - - 2014
Can serum anti-Müllerian hormone (AMH) levels measured in female adolescents predict polycystic ovary syndrome (PCOS)-associated features in adolescence and early adulthood? AMH levels associated well with PCOS-associated features (such as testosterone levels and oligoamenorrhoea) in adolescence, but was not an ideal marker to predict PCOS-associated features in early adulthood. Several ...
Porsbjerg C C Respiratosry Research Unit, Department of Respiratory Medicine, Bispebjerg University Hospital, Copenhagen, Denmark. Electronic address: - - 2014
Late onset asthma is associated with more severe disease and higher morbidity than in younger asthma patients. This may in part relate to under recognition of asthma in older adults, but evidence on the impact of patient age on diagnostic assessment of asthma in a specialist setting is sparse. To ...
Tartof Sara Y SY Department of Research and Evaluation, Kaiser Permanente Southern California, Pasadena. Electronic address: - - 2014
To describe incidence rates (IRs) of polymerase chain reaction (PCR)-diagnosed Clostridium difficile infection (CDI) in a large high-risk cohort. Members of Kaiser Permanente Southern California 1 year or older who were admitted to any of 14 Kaiser Permanente hospitals from January 1, 2011, through December 31, 2012, were included in ...
- - 2014
An estimated 1.3 million people over the age of 65 are believed to be malnourished in the UK.
Graffe Alix A Ophthalmology, Angers University Hospital, Angers, 49933, - - 2014
Purpose. Vitamin D insufficiency is associated with age-related macular degeneration. Our objective was to determine whether low serum 25-hydroxyvitamin D (25OHD) concentration was associated with macular thickness among older adults with no signs of macular dysfunction. Methods. Sixty-two French older community-dwellers with no patent macular dysfunction (mean±standard deviation, 71.2±5.0years; 45.2% ...
Messedi Emna E Microbiology Department, Habib Bourguiba Hospital/Faculty of Medicine, South University, Sfax, - - 2014
A large and unusually prolonged rubella outbreak occurred in Tunisia from April 2011 to July 2012 and was characterized by a high number of neurological cases. To describe the outbreak and to perform virus genotyping of isolated virus strains. From January 2011 to December 2012, 5000 sera for serological diagnosis ...
Kiuru Eveliina E Department of Surgery, Kuopio University Hospital and School of Medicine, University of Eastern Finland, Kuopio, - - 2014
Background: The impact of the age and sex adjusted body mass index (ISO-BMI) in the obese vs. non-obese children and adolescents with cholecystectomy for cholelithias is rarely reported. Patients and Methods: The national database was searched for cholecystectomies performed in paediatric patients between 1997 and 2011, and the 59 paediatric ...
Kitano Naomi N Department of Public Health, School of Medicine, Wakayama Medical - - 2014
Background: To clarify the contribution of patient age to the development of coronary artery lesions (CALs) associated with Kawasaki disease (KD), epidemiologic features and prognostic factors were investigated using hospital-based complete enumeration surveys in a specific area.Methods: Consecutive KD cases identified between October 1999 and September 2012 in Wakayama Prefecture, ...
Forbes Michael M Department of Pediatrics; Akron Children's Hospital; Akron, OH - - 2014
Monthly doses of palivizumab, an RSV-specific monoclonal antibody, reduce RSV-related hospitalizations (RSVH) in high-risk children; however, no specific palivizumab level has been correlated with disease severity in humans. A post hoc analysis of a previous randomized, placebo-controlled trial evaluated the relationship between serum palivizumab level at the time of RSVH ...
Kessler Jeffrey I JI Kaiser Permanente Southern California, Los Angeles, California, USA - - 2014
Osteochondritis dissecans (OCD) of the ankle is a disorder of the talar or distal tibial subchondral bone and articular cartilage whose incidence in children is not clearly known. To assess the demographics and epidemiology of OCD of the ankle in children. Descriptive epidemiologic study. A retrospective chart review of an ...
Cicero Arrigo Francesco Giuseppe AF Medical and Surgical Sciences Department, University of Bologna, Bologna, Italy, - - 2014
Contrasting evidence shows a possible association between serum uric acid (SUA) and cognitive function in elderly subjects. We aimed at evaluating the impact of circulating SUA levels on cognitive function in a cohort of pharmacologically untreated young elderly subjects. For this study, we selected 288 healthy young elderly participants from ...
Xie Liang L Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China; Institute of Neuroscience, Chongqing Medical University, Chongqing, China; Chongqing Key Laboratory of Neurobiology, Chongqing, - - 2014
The cynomolgus monkey (Macaca fascicularis) has been increasingly used in biomedical research. Although living conditions affect behavioral and physiological characteristics in macaques, little data is available on how living conditions influence blood-based parameters in the cynomolgus monkey. We hypothesize that there are significant differences in serum biochemical and hematological parameters ...
Herrick Kirsten A - - 2014
Data from the National Health and Nutrition Examination Survey (NHANES) and the NHANES National Youth Fitness Survey, 2012. Nearly all (98.5%) youth aged 12-15 reported watching TV daily. More than 9 in 10 (91.1%) youth aged 12-15 reported using the computer daily outside of school. In 2012, 27.0% of youth ...
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