Search Results
Results 1 - 50 of 1414
1 2 3 4 5 6 7 8 9 10 >
Schmauss Daniel D Klinik für Plastische Chirurgie und Handchirurgie, Klinikum rechts der Isar, Technische Universität München, Munich, - - 2014
The scores used to evaluate sensibility after digital nerve reconstruction do not take the patient's age into consideration, although there is evidence that the outcome after digital nerve reconstruction is age-dependent. However, it is not clear if the normal sensibility of the hand is also age-dependent, since the existing studies ...
Lefevre Carmen E CE Centre for Decision Research, Leeds University Business School, Leeds LS2 9JT, UK - - 2014
Recently, associations between facial structure and aggressive behaviour have been reported. Specifically, the facial width-to-height ratio (fWHR) is thought to link to aggression, although it is unclear whether this association is related to a specific dimension of aggression, or to a more generalized concept of dominance behaviour. Similarly, an association ...
Ozge Aynur A Department of Neurology, Mersin University School of Medicine, Mersin, - - 2014
Chronic migraine is a growing and disabling subtype of migraine with different risk factors and clinical features, even in older adults. We sought to define and differentiate clinical features of chronic migraine in older adults. We also aimed to compare major clinical features of chronic migraine in older adults with ...
Esquisatto Marcelo Augusto Marretto MA Biomedical Sciences Graduate Program, Hermínio Ometto University Center - UNIARARAS, Av. Dr. Maximiliano Baruto 500, PC 13607-339 Araras, SP, Brazil. Electronic address: - - 2014
The alterations due to aging in the peripheral nerves can affect the physiology of these structures. Thus, the purpose of the present study was to describe the activity of the MMP-2 and MMP-9, as well as the structure and composition of the extracellular matrix of the rat sciatic nerve during ...
Amer Mona G MG Histology & Cell Biology Department, Faculty of Medicine, Zagazig University, Egypt; Histology Department, Faculty of Medicine, Taif University, Saudi Arabia. Electronic address: - - 2014
Aging is associated with structural, functional and biochemical alterations in the nervous system. Calorie restriction (CR) was found to retard most physiological indices of aging. This work aimed to investigate the effect of CR on age-related changes in sciatic nerves. Thirty male albino rats aged 1 month were equally divided ...
Tsukitome Hideyuki H Department of Ophthalmology, Mie University Graduate School of Medicine, Tsu, - - 2014
To study changes in the opening angle of the optic nerve and the angle of the ocular orbit with increasing age in normal Japanese children. We studied 147 normal children (aged 6 months to 18 years) who had undergone CT as a diagnostic procedure. Measurements were performed on axial CT images that ...
Grantham James J Biological Anthropology and Comparative Anatomy Unit, The University of Adelaide, Australia. Electronic address: - - 2014
Many studies have focused on the detrimental effects of malnourishment to the performance of the brain and peripheral nerves. Undernourished children and adults have been studied extensively to establish these consequences. Little attention has been given to the body habitus that affects optimum neurological performance and the implications for individuals ...
Murakami Daisuke D Department of Pediatric Dentistry, Kagoshima University Graduate School of Medical and Dental Sciences, 8-35-1 Sakuragaoka, Kagoshima 890-8544, - - 2014
To evaluate morphological differences of the facial soft tissue surface between male Japanese adults and children. 20 adult Japanese males (average age 28 years) and 20 Japanese boys (average age 5.5 years) with normal occlusion were selected for this study. The images of the subjects' facial surface were obtained with ...
Wen Xing X Key Laboratory of Advanced Materials of Ministry of Education of China, Department of Chemical Engineering, Tsinghua University, Beijing 100084 (P.R. - - 2014
Poly(N,N'-methylenebisacrylamide-4-vinylpyridine) (P(MBA-4VP)) nanowires loaded with silver nanoparticles (Ag NPs) have been fabricated by silver metallogel template copolymerization, and subsequently, silver ions are reduced instead of the template being removed. Ag NPs with a diameter of 5-15 nm were dispersed throughout the core of P(MBA-4VP) nanowires. The size and distribution of the ...
Cui Guo-Gen GG School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou 510640, People's Republic of - - 2014
In the polymeric title compound, [Ag(C8H14N3)] n , the Ag(I) cation is coordinated by three N atoms from three 3,5-diisopropyl-1,2,4-triazolate anions in a T-shaped geometry. The Ag(I) cation deviates from the coordination plane by 0.014 (1) Å and the N-Ag-N bond angles are 96.85 (11), 97.72 (10) and 165.39 (12)°. The triazolate anion bridges three ...
Chang Kate Wan-Chu KW Department of Neurosurgery, University of Michigan, Ann Arbor, - - 2014
An association of language impairment with neonatal brachial plexus palsy has not been reported in the literature. The current treatment paradigm for neonatal brachial plexus palsy focuses on upper extremity motor recovery with little formal assessment of other aspects of development, such as language. We performed a cross-sectional pilot study ...
Dhahbi Joseph M JM Department of Biochemistry, University of California at Riverside, Riverside, CA 92521, USA; Center for Genetics, Childrens Hospital Oakland Research Institute, Oakland, CA 94609, USA. Electronic address: - - 2014
Small noncoding RNAs (sncRNAs) mediate a variety of cellular functions in animals and plants. Deep sequencing has made it possible to obtain highly detailed information on the types and abundance of sncRNAs in biological specimens, leading to the discovery that sncRNAs circulate in the blood of humans and mammals. The ...
Gupta Shashi Kumar SK Institute of Molecular and Translational Therapeutic Strategies (IMTTS), IFB-Tx, Hannover Medical School, Hannover, - - 2014
The increasing burden of ageing populations and their healthcare expenditure is a major challenge worldwide. Ageing is a complex disorder and can be defined as progressive decline in function with time leading to increased incidence of various cardiovascular, neurological and immunological diseases. The human genome comprises of many protein coding ...
Mu Ying Y College of Life Sciences and Biotechnology, Beijing Forestry University, Mail-box 162#, No. 35 Qinghua East Road, Haidian District Beijing, 100083 People's Republic of China ; National Engineering Laboratory for Tree Breeding, Beijing, 100083 People's Republic of China ; Key Laboratory of Genetics and Breeding in Forest Trees and Ornamental Plants, Ministry of Education, Beijing, 100083 People's Republic of China ; The Tree and Ornamental Plant Breeding and Biotechnology Laboratory of State Forestry Administration, Beijing, 100083 People's Republic of - - 2014
Telomeres and telomerase have important biological functions and can protect chromosome ends. In this study, sex- and season-dependent changes in telomere length and telomerase activity in ash and willow were analyzed. A statistical analysis showed that the telomere lengths of male and female trees differed significantly (P < 0.05). In ash, the ...
Abe Masashi M Department of Biology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, - - 2014
MicroRNAs (miRNAs) are 20- to ∼24-nucleotide (nt) small RNAs that impact a variety of biological processes, from development to age-associated events. To study the role of miRNAs in aging, studies have profiled the levels of miRNAs with time. However, evidence suggests that miRNAs show heterogeneity in length and sequence in ...
Pulliero Alessandra - - 2014
Aicardi Goutieres Syndrome (AGS) is characterized by mutations occurring in genes encoding RNAses. AGS mutations silence intracellular RNases resulting in an intracellular overload of short RNAs arresting the physiological production of microRNA required for brain development. MiR-219 is typically down-regulated in Aicardi Goutieres Syn-drome (AGS). The goal of this study ...
Petersen Johannes J Department of Radiology, Innsbruck Medical University, Anichstrasse 35, 6020, Innsbruck, - - 2013
Chronic apical periodontitis (CAP) appears to be a risk factor for coronary heart disease. The aims of the study were to estimate the significance of AP for the atherosclerotic burden and to examine the potential effect of endodontic treatment. The whole-body computed tomography (CT) examinations of 531 patients with a ...
Gendron Christi M CM Department of Molecular and Integrative Physiology and Geriatrics Center, Biomedical Sciences and Research Building, University of Michigan, Ann Arbor, MI 48109, - - 2014
Sensory perception can modulate aging and physiology across taxa. We found that perception of female sexual pheromones through a specific gustatory receptor expressed in a subset of foreleg neurons in male fruit flies, Drosophila melanogaster, rapidly and reversibly decreases fat stores, reduces resistance to starvation, and limits life span. Neurons ...
Zmora Nilli - - 2013
The crustacean male-specific androgenic hormone is widely accepted as a key factor in sexual differentiation and in the development of secondary sex characteristics. However, the mechanism by which the plethora of different reproductive strategies are controlled and executed in crustaceans is not known. We discovered in the blue crab, Callinectes ...
Cheng Guanghui - - 2013
Telomeres play an important role in the maintenance of genomic stability/integrity and are synthesized by the RNA-dependent polymerase telomerase. Progressive telomere shortening contributes to both in vitro and in vivo aging, and telomere length dynamics and telomerase expression profile in human tissues during extrauterine life have been well characterized. However, ...
Broulette Jonah J Actuarial Analyst, Milliman, New York, - - 2013
Community-acquired pneumonia (CAP) is frequently associated with the very young and the elderly but is a largely underrecognized burden among working-age adults. Although the burden of CAP among the elderly has been established, there are limited data on the economic burden of CAP in the employed population. To assess the ...
Carvalho Ana - - 2013
The expression of the ribosomal RNA (rRNA) genes from rye, located within the nucleolus organizer regions (NORs), is repressed by cytosine methylation in wheat x rye hybrids and in triticale, as consequence of nucleolar dominance. Our previous study revealed that bread wheat cultivars with a maximum number of four Ag-NORs ...
Lok Judith J JJ aHarvard School of Public Health bCenter for Biostatistics in AIDS Research, Harvard School of Public Health, Boston, Massachusetts cSFGH HIV/AIDS Division, University of California, San Francisco, California dUniversity of Washington School of Medicine, Seattle, Washington eUniversity of California, San Diego, California fDavid Geffen School of Medicine at UCLA and the Los Angeles Biomedical Institute of Research at Harbor-UCLA, Los Angeles, California gUniversity of Rochester Medical Center, Rochester, New York hUniversity of California, San Francisco, California, - - 2013
To assess whether CD8 T-cell activation predicts risk of AIDS and non-AIDS morbidity during suppressive antiretroviral treatment (ART). Post-hoc analyses of ART-naive participants in prospective ART studies. Participants with HIV-RNA levels 200 copies/ml or less and CD8 T-cell activation data (%CD38HLA-DR) at year-1 of ART were selected to determine years ...
Grant Philip M PM Division of Infectious Diseases, Department of Medicine, Stanford University, Palo Alto, - - 2013
Bone mineral density (BMD) decreases 2%-6% in the 2 years after antiretroviral therapy (ART) initiation. Pre-ART immune deficiency and early immune recovery may contribute to this loss. We pooled data from 3 studies of ART initiation in treatment-naive patients in which serial whole-body dual-energy X-ray absorptiometry scans were performed. We ...
Takahashi Kensuke - - 2013
Lower respiratory tract infection (LRTI) including Community-acquired pneumonia (CAP) is a common infectious disease that is associated with significant morbidity and mortality. The patterns of aetiological pathogens differ by region and country. Special attention must be paid to CAP in Southeast Asia (SEA), a region facing rapid demographic transition. Estimates ...
Tudela Rebeca - - 2013
In this study the catabolites derived from RNA degradation were assessed in Cava sparkling wines as a consequence of lees autolysis. For this purpose, the changes in the content of adenosine, guanosine, inosine, uridine, hypoxanthine, xanthine, and uric acid were determined by UHPLC-MS/MS, in sparkling wines produced on industrial scale, ...
Holmes Andrew P - - 2013
RNA editing is a post-transcriptional process, which results in base substitution modifications to RNA. It is an important process in generating protein diversity through amino acid substitution and the modulation of splicing events. Previous studies have suggested a link between gene-specific reductions in adenosine to inosine RNA editing and aging ...
Sato Reiko - - 2013
BACKGROUND: Community-acquired pneumonia (CAP) causes substantial clinical and economic burden. While several studies have reported the cost to treat CAP, there is little information on the cost to treat by age, risk profile, and hospitalization in US adults aged ≥50 years. OBJECTIVE: To quantify the cost, from a payer perspective, of ...
Wyrwich Kathleen W - - 2013
PURPOSE: Community-acquired pneumonia (CAP) is a leading cause of morbidity and mortality in older adults, yet few studies have comprehensively measured the burden of CAP symptoms and their impact from the patient perspective. Our Web-survey used the newly developed CAP burden of illness questionnaire (CAP-BIQ) designed to assess the presence ...
Farkas Jordan P JP Department of Plastic Surgery, University of Texas Southwestern Medical Center, Dallas, - - 2013
The etiology of age-related facial changes has many layers. Multiple theories have been presented over the past 50-100 years with an evolution of understanding regarding facial changes related to skin, soft tissue, muscle, and bone. This special topic will provide an overview of the current literature and evidence and theories ...
Jorgensen Anders - - 2013
Schizophrenia is associated with a substantially increased somatic morbidity and mortality, which may partly be caused by accelerated cellular aging. Oxidative stress is an established mediator of aging and a suggested aetiological mechanism in both schizophrenia and age-related medical disorders such as cardiovascular disease, type 2 diabetes and dementia. We ...
Justice Amy C AC Department of Internal Medicine, Yale University and the Veterans Affairs Healthcare System, West Haven, CT 06516, USA. - - 2013
By supplementing an index composed of HIV biomarkers and age (restricted index) with measures of organ injury, the Veterans Aging Cohort Study (VACS) index more completely reflects risk of mortality. We compare the accuracy of the VACS and restricted indices (1) among subjects outside the Veterans Affairs Healthcare System, (2) ...
Gessner Bradford D - - 2012
We evaluated pneumococcal serotype/group distribution using polymerase chain reaction (PCR) testing on cerebrospinal fluid collected from patients from Burkina Faso and Togo who presented for care during 2007-2009. We identified 282 pneumococcal meningitis cases based on PCR, latex agglutination, or culture, of which 206 underwent serotyping. Serotype 1 was identified ...
Rieux Anais - - 2012
A longitudinal study was undertaken to characterize the course of Cryptosporidium infection in a dairy goat farm located in western France. Two cohorts of twenty-five and fifteen animals, respectively, were sampled once a week from birth to weaning. Each individual fecal sample was screened using direct immunofluorescence (IFT) and if ...
Qi Baiyu - - 2013
Bloodstain age is a parameter that can be used in crime scene investigations. Bloodstain age can be determined by measuring the 18S rRNA:β-actin mRNA ratio by Reverse Transcription-quantitative PCR (RT-qPCR). Since this ratio is a function of time, it can be used as an estimator of bloodstain age. However, it ...
Li Han-Mei - - 2012
A novel anionic PEG derivative with a wheat-like structure, PEG-poly(AGE-Suc) was synthesized. The spikelet part of this polymer consisted of 9.3 pairs of carboxylic acid-side chains was conjugated at one end of the PEG chain. The neutral linear PEG1580 was designed as the stalk part to improve the biocompatibility of ...
Chang Anne Lynn S - - 2013
Studies in model organisms suggest that aged cells can be functionally rejuvenated, but whether this concept applies to human skin is unclear. Here we apply 3'-end sequencing for expression quantification ("3-seq") to discover the gene expression program associated with human photoaging and intrinsic skin aging (collectively termed "skin aging"), and ...
Landau Susan M - - 2012
To assess the association between lifestyle practices (cognitive and physical activity) and β-amyloid deposition, measured with positron emission tomography using carbon 11-labeled Pittsburgh Compound B ([(11)C]PiB), in healthy older individuals. Cross-sectional clinical study. Berkeley, California. Volunteer sample of 65 healthy older individuals (mean age, 76.1 years), 10 patients with Alzheimer ...
Forni Cristiana - - 2012
Knowledge about the long-term sequelae of rotationplasty, in adults treated surgically in childhood for Osteosarcoma in the lower limb, mainly concerns function and performance; the aim of this study is to explore the experience and the Quality of Life (QoL) of the patients who underwent Rotationplasty from 1986 to 2006 ...
Greenspan Robin L - - 2012
: The purpose of this study was to evaluate frequency, intensity, and associations of distal spinal cord F-18 FDG uptake visible on PET/CT. Normal cervical, but not distal cord uptake, has been reported previously. : This is a retrospective review of consecutive oncologic whole body PET/CTs from 14 June, 2006 ...
Mangerich Aswin - - 2012
Aging is a multifactorial process that depends on diverse molecular and cellular mechanisms, such as genome maintenance and inflammation. The nuclear enzyme poly(ADP-ribose) polymerase 1 (PARP1), which catalyzes the synthesis of the biopolymer poly(ADP-ribose), exhibits an essential role in both processes. On the one hand, PARP1 serves as a genomic ...
Alic Nazif N Institute of Healthy Ageing, and GEE, University College London, London, United Kingdom. - - 2012
RNA interference (RNAi) provides an important tool for gene function discovery. It has been widely exploited in Caenorhabditis elegans ageing research because it does not appear to have any non-specific effects on ageing-related traits in that model organism. We show here that ubiquitous, adult-onset activation of the RNAi machinery, achieved ...
Dahlbom S Josefin - - 2011
Social defeat is a common model for studies on depression. However, such models are most often used to study aggression in males and sex differences in depression may therefore be overseen. This study investigated the potential of the zebrafish (Danio rerio) as a model for male and female aggression. In ...
Sperling Karl - - 2011
The objective of this study is to investigate the prevalence of Down syndrome (DS) associated with Chernobyl fallout. Maternal age-adjusted DS data and corresponding live birth data from the following seven European countries or regions were analyzed: Bavaria and West Berlin in Germany, Belarus, Hungary, the Lothian Region of Scotland, ...
Kranz Jasmin - - 2013
To analyse whether the permeability of the blood-brain barrier to the antimuscarinic drug trospium chloride is altered with ageing. This is a relevant question for elderly patients with overactive bladder syndrome who are treated with trospium chloride as the occurrence of adverse effects on the central nervous system (CNS) highly ...
Stoduto Gina - - 2011
BACKGROUND: Cocaine is one of the more commonly found illicit drugs in injured drivers. In this work, we examine the association between self-reported past year cocaine use and past year collision involvement in a large representative sample of adult drivers in Ontario. METHODS: Data are based on the CAMH Monitor, ...
Aragão Florbela da Rocha - - 2011
The aim of this study was to identify the effects of body composition and menopause characteristics on maximal oxygen uptake (V˙O2max) variation in postmenopausal women. The study was conducted on 208 healthy women aged 49 to 79 years. Data related to menopause were obtained through medical history. Measurements of fat ...
Bucerius Jan J Translational and Molecular Imaging Institute, Mount Sinai School of Medicine, New York, New York 10029, - - 2011
We investigated the prevalence and clinical risk factors of carotid vessel wall inflammation by means of 18F-fluorodeoxyglucose positron emission tomography (FDG-PET) in a population consisting of coronary artery disease (CAD) patients. The atherosclerotic disease process is characterized by infiltration and retention of oxidized lipids in the artery wall, triggering a ...
Wong Ka Kit - - 2011
Gender differences in brain dopaminergic activity have been variably reported in the literature. We performed an evaluation for gender effects on striatal dopamine transporter (DAT) binding in a group of normal subjects. Community-dwelling adults (n=85, 50F/35M, mean age 62.7±16.2 SD, range 20-85) underwent DAT [(11)C]2-β-carbomethoxy-3β-(4-fluorophenyl) tropane (β-CFT) positron emission tomography ...
Patil Sumit T - - 2011
A total 375 Indian children of age 1 day to 19 years were studied (male 194 and female 181). For determining the bone age (skeletal age), wrist and hand radiographs were taken. The skeletal age was determined by blinded review of radiograph using Greulich and Pyle atlas (2nd edition, 1959). ...
1 2 3 4 5 6 7 8 9 10 >