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Results 301 - 350 of 1462
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Le Couteur David G - - 2011
In the past, it has been assumed that all the biological and medical changes that occur in old age are deleterious. It has therefore been concluded that treatment and prevention of such changes in old age should increase healthspan and delay death. However, accruing epidemiological and clinical trial evidence in ...
Bonnie Linda H A - - 2010
With the increasing interest in lifestyle, health and consequences of unhealthy lifestyles for the healthcare system, a new kind of solidarity is gaining importance: lifestyle solidarity. While it might not seem fair to let other people pay for the costs arising from an unhealthy lifestyle, it does not seem fair ...
Carey James R JR Department of Entomology, University of California, Davis, CA 95616, USA. - - 2011
The purpose of this paper is to summarize recent research on longevity, aging and adaptation in wild medfly populations and in a close relative of the medfly. The key findings include a new life table identity that relates age structure and the distribution of deaths in stationary populations, seasonal variation ...
Borries Carola - - 2011
Primate life histories are strongly influenced by both body and brain mass and are mediated by food availability and perhaps dietary adaptations. It has been suggested that folivorous primates mature and reproduce more slowly than frugivores due to lower basal metabolic rates as well as to greater degrees of arboreality, ...
Coyula Miguel - - 2010
In Cuba, various factors have led to nearly zero population growth and a rapidly aging society. In a few years, the rush of baby-boomers reaching retirement will stand the population pyramid on its head, as the country's life expectancy already nears 80 years. Almost 20% of all Cubans live in ...
Cholbi Michael - - 2010
This article addresses the question of whether the arguments for a duty to die given by John Hardwig, the most prominent philosophical advocate of such a duty, are sound. Hardwig believes that the duty to die is relatively widespread among those with burdensome illnesses, dependencies, or medical conditions. I argue ...
Koch Tina - - 2010
To present alternative stories of ageing that countered the prevailing negative stereotypes of older people by interviewing centenarians about their lives. Sixteen healthy U.K. centenarian volunteers were interviewed in their place of residence. A story draft was produced using the interview recording and verbatim transcript. The four researchers collaborated to ...
Feser Jason J Department of Biochemistry and Molecular Genetics, University of Colorado School of Medicine, Aurora, CO 80010, - - 2010
Changes to the chromatin structure accompany aging, but the molecular mechanisms underlying aging and the accompanying changes to the chromatin are unclear. Here, we report a mechanism whereby altering chromatin structure regulates life span. We show that normal aging is accompanied by a profound loss of histone proteins from the ...
Boyle Patricia A PA Rush Alzheimer's Disease Center, Chicago, Illinois 60612, USA. - - 2010
To examine the association between life space, a measure of functional status that describes the range of movement through the environment covered during daily functioning, and the risk of mortality in older community-based persons. Two ongoing, prospective observational cohort studies of aging. Greater metropolitan Chicago area. One thousand four hundred ...
Sudnongbua Supaporn - - 2010
The purpose of this study was to determine the extent to which older persons in rural Northeast Thailand felt abandoned by the emigration of their children and the impact this may have on their quality of life. A cross sectional survey, consisting of 113 questions including the 26-item WHOQOL-BREF and ...
Carriere Jonathan S A - - 2010
Recent research has revealed an age-related reduction in errors in a sustained attention task, suggesting that sustained attention abilities improve with age. Such results seem paradoxical in light of the well-documented age-related declines in cognitive performance. In the present study, performance on the sustained attention to response task (SART) was ...
Cohen Carl I - - 2010
This study examined a community sample of older adults with schizophrenia to determine whether there were differences in religiousness with their age peers, to examine the relationship between religiousness and psychotic symptoms, and to see whether religiousness has direct or stress-buffering effects on quality of life. The schizophrenia group consisted ...
Kavé Gitit - - 2010
Picture-naming performance for 48 black-and-white drawings was investigated in 1,145 Hebrew speakers, ages 5-86. Both a linear and a curvilinear quadratic model fit the data, reflecting an increase in ability with age as well as an increase followed by a decrease beyond that linear rise. Late-life performance was more affected ...
Cho Irene - - 2010
Life history theory hypothesizes that genetically based variation in life history traits results from alleles that alter age-specific patterns of energy allocation among the competing demands of reproduction, storage, and maintenance. Despite the important role that alleles with age-specific effects must play in life history evolution, few naturally occurring alleles ...
Das Dipak K - - 2010
Resveratrol, a polyphenol phytoalexin, present in red wine and grapes possesses diverse biochemical and physiological properties, including estrogenic, antiplatelet, and anti-inflammatory properties as well as a wide range of health benefits ranging from chemoprevention to cardioprotection. Recently, several studies described resveratrol as an anti-aging compound. This review focuses on the ...
Mouchiroud Laurent - - 2010
Life expectancy at the turn of the 20th century was 46 years on average worldwide and it is around 65 years today. The correlative increase in age-associated diseases incidence has a profound public health impact and is an important matter of concern for our societies. Aging is a complex, heterogeneous, ...
Gerstorf Denis D Department of Human Development and Family Studies, Pennsylvania State University, University Park, PA 16802, USA. - - 2010
Life-span psychological research has long been interested in the contextual embeddedness of individual development. To examine whether and how regional variables relate to between-person disparities in the progression of late-life well-being, we applied three-level growth curve models to 24-year longitudinal data from deceased participants of the German Socio-Economic Panel Study ...
Bowling Ann - - 2011
Most measures of quality of life (QoL) are based on 'expert' opinions. This study describes a new measure of QoL in older age, the Older People's QoL Questionnaire (OPQOL), which is unique in being derived from the views of lay people, cross-checked against theoretical models for assessment of comprehensiveness. Its ...
Steinberg Daniel - - 2010
The thesis advanced here is that we are initiating treatment of hypercholesterolemia (and other risk factors) too late in life. Initiating treatment at, for example, age 30 years instead of age 60 years might very well prevent not just 30% of events, as in the 5-year statin trials, but perhaps ...
Carter Kristie N - - 2010
BACKGROUND: Survival and life expectancy are commonly used metrics to describe population health. There are two objectives to this paper: (1) to provide an explanation of methods and data used to develop New Zealand life-tables by ethnic, income and smoking groups; and (2) to compare cumulative survival and life expectancy ...
Webb Elizabeth - - 2011
Objective To investigate whether changes in health, social and economic circumstances predict change in quality of life (QoL) at older ages. Design Secondary analysis, using multiple regression analyses, of waves 1 and 3 of the English Longitudinal Study of Ageing. Setting England, 2002-6. Participants A nationally representative sample of non-institutionalised ...
Urfer Silvan R SR Department of Pathology, University of Washington, Seattle, WA 98195-7470, USA.. - - 2011
Clinical data from 72 dog breeds of varying size and life expectancy were grouped according to breed body mass and tested for prevalence at ages 4 to 5, ages 7 to 10, and lifetime incidence of non-hereditary, age-related cataract (ARC). The incidence of ARC was found to be directly related ...
Basha Riyaz - - 2010
Role of developmental exposure to environmental agents in altering the disease process is well known. Exposure to chemical agents at critical periods of development may cause some permanent changes in the functioning of various vital systems including the nervous system in the organisms. It is not surprising to see an ...
Lindeboom Maarten - - 2010
Nutritional conditions in utero and during infancy may causally affect health and mortality during childhood, adulthood, and at old ages. This paper investigates whether exposure to a nutritional shock in early life negatively affects survival at older ages, using individual data. Nutritional conditions are captured by exposure to the Potato ...
Palgi Yuval - - 2010
OBJECTIVE: The present study investigated time perspective in old-old age as embodied in trajectories of life satisfaction ratings that individuals attribute to their past, present, and anticipated future. We hypothesized that these trajectories represent diverse strategies of coping with old age. METHOD: The sample was composed of 164 participants (mean ...
Boongird Sarinya - - 2010
Nocturia is a frequently encountered problem in clinical practice and a reason for nephrology consultation. Many studies have clearly shown the negative effect of nocturia on several aspects of health-related quality of life and morbidity. Age-associated physiological, structural, hormonal, and histological changes play an important role in the increasing incidence ...
Vinyoles D - - 2010
The life-history tactics of the stone loach Barbatula barbatula were studied in a Mediterranean-type climate stream (Matarranya River) located in the Ebro River basin (north-east Spain). Maximum observed ages were 2+ years in both sexes (1% of individuals), although only 0+ and 1+ year age groups were well represented. It ...
Jung Minsoo - - 2010
OBJECTIVES: This study attempted to explore the aging phenomena that now characterize much of Korean society, and assessed issues associated with the life satisfaction experienced during the process of aging. METHODS: By employing the National Survey on the State of Life and the Desire for Welfare of the Elderly, 2004 ...
Dolan G - - 2010
Life expectancy for haemophilia has increased significantly in many countries. This represents a major success of the improved safety of therapeutic materials to treat haemophilia and of improved quality of care. This improved longevity will generate a population of older individuals with haemophilia with complex medical problems associated with age ...
Redelings Matthew - - 2010
Homicide is one of the leading causes of death in Los Angeles County and is known to be elevated in low-income urban neighborhoods and in black males. However, because homicide occurs primarily among young adults, mortality rate statistics may underrepresent its importance. We estimated the impact of homicide on life ...
Butcher Howard Karl - - 2010
This phenomenological investigation sought to enhance understanding of the experience of dispiritedness by providing a rich and vivid description of the essential structure of the experience in later life. van Manen's hermeneutic-phenomenological method was used to analyze the transcribed texts of 11 individuals who identified themselves as being in "later ...
Arias Elizabeth E U.S. Department of Health & Human Services, Centers for Disease Contorl and Prevention, National Center for Health Statistics, Division of Vital Statistics, Hyattsville, MD 20782, - - 2010
this report presents complete period life tables by age, race, and sex for the United States based on age-specific death rates in 2006. Data used to prepare the 2006 life tables are 2006 final mortality statistics, July 1, 2006 population estimates based on the 2000 decennial census, and 2006 Medicare ...
Vogt Günter - - 2010
This article examines the suitability of the parthenogenetic marbled crayfish for research on ageing and longevity. The marbled crayfish is an emerging laboratory model for development, epigenetics and toxicology that produces up to 400 genetically identical siblings per batch. It is easily cultured, has an adult size of 4-9 cm, ...
Ishida Yasushi - - 2010
To examine the late effects and health-related quality of life of childhood cancer survivors (CCS) after radiotherapy (RT), we performed a cross-sectional survey using self-rating questionnaires. The subjects were divided into 3 groups: CCS treated with or without RT, and a general population matched for age, gender, residential area, and ...
Sandroni Claudio - - 2010
To identify factors associated with candidate outcome in the European Resuscitation Council (ERC) advanced life support (ALS) provider courses. Medical doctors participating as candidates to consecutive ALS courses organised by an ERC training centre in Italy were enrolled in this prospective cohort study. The association between the ALS course outcome ...
Odlaug Brian L - - 2010
Pathological skin picking (PSP) and trichotillomania (TTM) are disorders characterized by distress and impaired functioning. This study sought to compare quality of life for individuals with PSP or TTM. PSP or TTM subjects completed the quality of life inventory and valid and reliable measures of clinical severity. Analyses included group ...
Na'amnih Wasef - - 2010
To examine trends in the Arab-Jew life expectancy gap in Israel during 1975-2004 and to determine the contribution of age groups and causes of death to changes in the gap. Data on life expectancy and mortality rates by cause of death, for Arabs and Jews, were obtained from the Israel ...
Bakheit Abdel Magid - - 2010
Although there are sound theoretical reasons for the use of botulinum toxin (Btx) as early as possible in the management of severe childhood muscle spasticity, the experience with its safety in children younger than 2 years of age is limited and information about its possible effects on the development and ...
Ponnudurai R - - 2010
Although the evidences for the phenomenon of "anticipation" and parental "imprinting" have been shown in schizophrenia, they are inconclusive. The purpose of this study was to test these hypotheses by examining three successive generations. 58 schizophrenic patients who had their maternal or paternal parent or grandparent, or both, affected with ...
Gerstorf Denis D Department of Human Development and Family Studies, Pennsylvania State University, University Park, PA 16802, USA. - - 2010
Throughout adulthood and old age, levels of well-being appear to remain relatively stable. However, evidence is emerging that late in life well-being declines considerably. Using long-term longitudinal data of deceased participants in national samples from Germany, the United Kingdom, and the United States, we examined how long this period lasts. ...
Gersten Omer O National Health Research Institutes, Institute of Population Health Sciences, Division of Health Policy Research and Development, No. 35 Keyan Road, Zhunan, Miaoli County 350, Taiwan. - - 2010
A key aspect of the increasingly popular allostatic load (AL) framework is that stressors experienced over the entire life course result in physiological dysregulation. Although core to AL theory, this idea has been little tested, and where it has been tested, the results have been mixed. The study analyzes the ...
Beckerman Andrew P - - 2010
1. Two major theories underpin our understanding of how predation risk shapes life history. The first is centred around predator induced changes in activity that subsequently reduce food intake and thus growth. The second is centred around size selective, predator induced changes in development. 2. Here, we challenge these theories ...
García-Villamisar D A - - 2010
BACKGROUND: Even though there is research demonstrating a positive relationship between leisure participation and the two constructs of quality of life and stress reduction, current conceptualisation of leisure as a contributor to quality of life is limited. In addition, in spite of improvements in accurate diagnosis of autism spectrum disorder ...
English S - - 2010
Although recent models for the evolution of personality, using game theory and life-history theory, predict that individuals should differ consistently in their cooperative behaviour, consistent individual differences in cooperative behaviour have rarely been documented. In this study, we used a long-term data set on wild meerkats to quantify the repeatability ...
Blagosklonny Mikhail V - - 2010
In 2006, Cell Cycle featured the concept that aging is not caused by molecular damage (nor by free radicals) but instead is a purposeless quasi-program (program-like, but not a program) driven in part by TOR (Target of Rapamycin). Taken together with the analysis of clinical data, this pointed to Sirolimus ...
Ishida Yasushi - - 2010
To examine the late effects and health-related quality of life among childhood cancer survivors (CCS) after stem cell transplantation (SCT), we performed a cross-sectional survey using self-rating questionnaires. The subjects were divided into 3 groups: SCT-treated CCS, CCS treated without SCT, and the general population who matched for age, gender, ...
Honda Yoko - - 2010
Trehalose is a disaccharide of glucose found in diverse organisms and is suggested to act as a stress protectant against heat, cold, desiccation, anoxia, and oxidation. Here, we demonstrate that treatment of Caenorhabditis elegans with trehalose starting from the young-adult stage extended the mean life span by over 30% without ...
Auger Claudine - - 2010
OBJECTIVE: To examine whether the impact of power mobility devices (PMDs) varies as a function of stage of usage and to explore key factors associated with greater life-space mobility for middle-aged and older adults. DESIGN: Multicohort study with respondents grouped as a function of stage of PMD usage (reference group ...
Lee Mary T - - 2010
The impact of a total laryngectomy on an individual's life has primarily been measured from a male viewpoint reflecting the demographics of a diagnosis of laryngeal cancer. A small number of studies have looked specifically at females, but very few are comparison studies. Consequently, there is little consistent research regarding ...
Johnson Monica Kirkpatrick - - 2010
This study revisits the relationship between adolescent judgments about work and later job characteristics, tackling the twin temporal dimensions of age and history. Drawing on 15 consecutive cohorts of high school seniors, we examine 1) whether adolescents' judgments about work become more strongly predictive of the characteristics of their jobs ...
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