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Results 1 - 50 of 2006
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Kucharski A J AJ Department of Infectious Disease Epidemiology,London School of Hygiene & Tropical - - 2014
SUMMARY The age distribution of influenza A(H5N1) cases reported during 2006-2013 varied substantially between countries. As well as underlying demographic profiles, it is possible that cross-immunity contributed to the age distribution of reported cases: seasonal influenza A(H1N1) and avian influenza A(H5N1) share the same neuraminidase subtype, N1. Using a mechanistic ...
Chakravarti Anita A Director Professor and Head of the Department, Department of Microbiology, Maulana Azad Medical College, India - - 2014
Dengue is a major public health problem in India. We evaluated clinical and laboratory characteristics of 700 suspected dengue patients below the age of 12 years. Serum samples of the patients were analysed for dengue NS1 antigen and IgM antibody by ELISA, and were correlated with clinical and haematological parameters. ...
Li Ping P 1 Tumor Etiology and Screening Department of Cancer Institute and General Surgery, The First Affiliated Hospital of China Medical University , Shenyang, People's Republic of China - - 2014
Aims: Toll-like receptor 4 (TLR4) plays an important role in gastric carcinoma. Using a case-control study, we analyzed the genotypic distribution of TLR4 rs10983755 (-2081G/A) and rs11536878 in a Chinese population and investigated the effect of their interactions with Helicobacter pylori infection on susceptibility to gastric cancer (GC) and atrophic ...
Mombaur Busisiwe B Neurology Research Group, Division of Neurology Department of Medicine, University of Cape - - 2014
Introduction: To assess age- and gender-specific incidence rates (IR) of acetylcholine receptor (AChR)-antibody positive myasthenia gravis (MG) in South Africa, and geographical variation in incidence. Methods: IRs were calculated from positive AChR-antibody laboratory data between 2011 and 2012, using 2011 population census data. Results: 890 individuals were seropositive, for an ...
Khandaker Golam M GM Department of Psychiatry, University of Cambridge, UK; Cambridgeshire and Peterborough NHS Foundation Trust, Cambridge, UK; Centre for Mental Health, Addiction and Suicide Research, School of Social and Community Medicine, University of Bristol, UK. Electronic address: - - 2014
Several studies suggest a link between early-life infection and adult schizophrenia. Cross-sectional studies have reported: (1) increased prevalence of Epstein-Barr Virus (EBV), a member of the Herpesviridae family in schizophrenia; (2) a possible role of Herpes simplex virus in cognitive dysfunction in schizophrenia and healthy controls. We report a longitudinal ...
Couppé Christian C Institute of Sports Medicine, Department of Orthopaedic Surgery M, Bispebjerg Hospital and Center for Healthy Aging, Faculty of Health Sciences, University of Copenhagen, Bldg. 8, Bispebjerg Bakke 23, DK-2400, Copenhagen, NV, Denmark, - - 2014
Life-long regular endurance exercise is known to counteract the deterioration of cardiovascular and metabolic function and overall mortality. Yet it remains unknown if life-long regular endurance exercise can influence the connective tissue accumulation of advanced glycation endproducts (AGEs) that is associated with aging and lifestyle-related diseases. We therefore examined two ...
Tansley Sarah L SL Royal National Hospital for Rheumatic Diseases NHS Foundation Trust, Department of Pharmacy and Pharmacology, University of Bath, Department of Mathematical Sciences, University of Bath, Bath, Department of Rheumatology, Southmead Hospital, North Bristol NHS Trust, Bristol, Rheumatology Unit, University College London Institute of Child Health and Arthritis Research UK Centre for Adolescent Rheumatology at University College London, University College London Hospital and Great Ormond Street Hospital, London, - - 2014
Calcinosis is a major cause of morbidity in JDM and has previously been linked to anti-NXP2 autoantibodies, younger age at disease onset and more persistent disease activity. This study aimed to investigate the clinical associations of anti-NXP2 autoantibodies in patients with JDM stratified by age at disease onset. A total ...
Yang Yifen Y Department of Clinical Laboratory, 2nd Xiangya Hospital, Central South University, Changsha, Hunan, - - 2014
Recently, the abnormal presence of thyroglobulin antibody (TG-Ab) and thyroid peroxidase antibody (TPO-Ab) has been reported in vitiligo patients, but presence of TG-Ab and TPO-Ab in patients of different ages and gender, and its association with vitiligo and thyroid autoimmunity has rarely been reported. The aim of our research was ...
Roeder Kathryn M KM Vanderbilt - - 2014
The link between the experience of peer victimization (PV) and future psychological maladjustment has been consistently documented; however, little is known about intermediary cognitive processes that underlie this relation or how these processes vary across childhood. The present study examined the prospective relations between physical and relational PV and the ...
Lee Adrienne A Department of Medicine, University of Calgary, Calgary, AB, - - 2014
We investigated a case of acquired von Willebrand syndrome (AVWS) secondary to a non-neutralizing anti-VWF antibody associated with an autoimmune disorder. At diagnosis, VWF activity (VWF:Act), antigen (VWF:Ag), multimers and FVIII:C were virtually absent. VWF propeptide (VWFpp) was elevated with infinitely high VWFpp to VWF:Ag ratio (VWFpp:Ag) consistent with rapid ...
Chen Li L Department of Orthopedics, Huashan Hospital, Fudan University, Shanghai 200040, - - 2014
A causal link between the metatarsus adductus and hallux valgus is not clear. The aim of this study was to investigate the configurations of the metatarsus adductus deformity by radiological measurements and reappraise the relationship between hallux valgus and metatarsus adductus. The first step was evaluation of the relationship between ...
Lu Ying-Ying YY Kidney Disease Center, the First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310003, China; Institute of Aging Research and Max-Planck-Research Group on Stem Cell Aging, Hangzhou Normal University, Hangzhou 311121, - - 2014
Aging is one of the contributing risk factors for kidney diseases. Accumulating evidence prompts the view that telomere length in kidney tissue cells is an indicator for organismal aging. Previously identified aging markers (cathelin-related antimicrobial peptide (CRAMP), stathmin, elongation factor-1α (EF-1α), and chitinase) were associated not only with telomere driven ...
Orivuori Laura L Department of Vaccination and Immune Protection, National Institute for Health and Welfare, Helsinki, - - 2014
Serum immunoglobulin A (IgA) and immunoglobulin G (IgG) antibodies against wheat gliadin and cow's milk β-lactoglobulin (BLG) are considered markers of gut permeability and inflammation which modulate the development of mucosal tolerance. Living on a farm has been shown to decrease allergies in children. Our aim was to study whether ...
Andreotti Gabriella G NCI, Rockville, MD, - - 2014
Epidemiologic studies have linked pesticide use to various health outcomes, including cancer, but underlying mechanisms remain unclear. In a previous analysis from the Agricultural Health Study (AHS), a prospective cohort study of pesticide applicators in the US, use of certain pesticides was linked to shorter relative telomere length (RTL) measured ...
Nohara A A Department of Lipidology, Kanazawa University Graduate School of Medical Sciences, Kanazawa, - - 2014
The LDL receptor relative with 11 ligand-binding repeats (LR11) is closely related to atherosclerotic disease or diabetes. The aim of the study was to clarify how soluble LR11 was related to Achilles' tendon thickness (ATT) and HbA1c in familial hypercholesterolemia DESIGN AND METHODS: The present study is a cross-sectional case-control ...
Condon Lawrence M LM Department of Pediatrics, HealthPartners, Bloomington MN - - 2014
Background. Primary Epstein-Barr virus (EBV) infection affects the host differently according to when in life it is acquired. Understanding risk factors for infection could be important for disease prevention and the age-specific prevalence of infection must be known to optimize use of a prophylactic vaccine. Methods. Children 18 months to 19.9 years ...
Kariya Shingo S Department of Pathology and Cell Biology, Center for Motor Neuron Biology and Disease and the Columbia Translational Neuroscience Initiative, Columbia University Medical Center , New - - 2014
Sporadic amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease with no established biological marker. Recent observation of a reduced number of gems (survival motor neuron protein (SMN)-positive nuclear bodies) in cells from patients with familial ALS and the mouse models suggests an involvement of SMN in ALS pathology. At ...
Wideman R F RF Jr Division of Agriculture, - - 2014
Two experiments (E1, E2) were conducted to compare the influence of sires (sire A on dam C vs. sire B on dam C) and straight-run versus sex-separate rearing on the incidence of bacterial chondronecrosis with osteomyelitis (BCO) in broilers. Fertile eggs from commercial breeder flocks were incubated and hatched at ...
Lee Soo Young SY 0000-0002-5354-3135 Department of Pediatrics, College of Medicine, The Catholic University of Korea, Seoul, Korea. ; Vaccine Bio Research Institute, College of Medicine, The Catholic University of Korea, Seoul, - - 2014
This study was conducted to evaluate age-specific seroprevalence of pertussis in Korea and to formulate a strategy to prevent and reduce the incidence of pertussis. Residual serum samples of healthy adolescents and adults 11 yr of age or older were collected between July 2012 and December 2012, and anti-pertussis toxin ...
Lee Ji-Young JY Department of Food Bioscience and Technology, College of Life Science & Biotechnology, Korea - - 2014
Advanced glycation end-products (AGEs) have been implicated in the development of diabetic complications. We report the antiglycating activity of chebulic acid (CA), isolated from Terminalia chebula on breaking the cross-links of proteins induced by AGEs and inhibiting the formation of AGEs. Aminoguanidine (AG) reduced 50% of glycated BSA with glycolaldehyde ...
Sperotto Francesca F From the Department of Pediatrics, University of Padua, Padua, - - 2014
The role of antinuclear antibodies (ANA) in children has still to be elucidated. The aim of our study was to evaluate the prevalence and persistence of ANA in schoolchildren during the puberty switch, and the possible relationship with chronic noninflammatory musculoskeletal pain (MSP). Children aged 8-13 years and attending 4 ...
Nishida Yuichiro Y Department of Preventive Medicine, Faculty of Medicine, Saga University, Nabeshima 5-1-1, Saga 849-8501, Japan. Electronic address: - - 2014
Studies using self-reported physical activity (PA) showed that higher PA is associated with lower circulating levels of C-reactive protein, in contrast, studies investigating associations of objective PA and other inflammatory markers are limited. We investigated cross-sectional associations of accelerometer-determined PA with circulating levels of myokine-type inflammatory cytokines in a middle-aged ...
Jones Jeffrey L JL Division of Parasitic Diseases and Malaria, Center for Global Health, Centers for Disease Control and Prevention, Atlanta, Georgia; Division of Health and Nutrition Examination Statistics, National Center for Health Statistics (NCHS), Centers for Disease Control and Prevention, Hyattsville, - - 2014
Toxoplasma gondii is a ubiquitous parasite that can cause neurologic and ocular disease. We tested sera from 7,072 people ≥ 6 years of age in the 2009-2010 National Health and Nutrition Examination Survey (NHANES) for immunoglobulin G antibodies and compared these results with two previous NHANES surveys. The overall T. ...
Alfadhli Suad S Department of Medical Laboratory Sciences, Faculty of Allied Health Sciences, Kuwait University , - - 2014
Abstract Background: Variations in IRF5 have been associated with an increased risk of developing lupus (SLE). Aim: To explore the association of IRF5 markers (rs2004640, rs10954213) with susceptibility to SLE and to the development of more than one autoimmune disease (OP) and to analyse the influence of rs2004640 on IRF5 ...
van Beek N N Department of Dermatology, Allergology and Venereology, University of Luebeck, Ratzeburger Allee 160, D-23538, Lübeck, - - 2014
Bullous pemphigoid (BP) is a subepidermal blistering autoimmune disease characterized by autoantibodies against two structural proteins of the epidermal basal membrane zone (BMZ), BP180 (type XVII collagen) and BP230. Patients are usually old and suffer from severe pruritus. Advanced age and severe pruritus have been hypothesized as potential risk factors ...
Das Karuna M KM Department of Medical Imaging, Prince Salman Heart Center, King Fahad Medical City, PO Box 59049, Riyadh, 11512, Saudi Arabia, - - 2014
This retrospective study aimed to determine the superior vena cava (SVC) and left innominate vein (INV) normative cross-sectional area in children noninvasively using age as a predictor and also to compare the correlation of the area measured with the diameter on multidetector computed tomography (MDCT). Analysis of the SVC-INV cross-sectional ...
Gartstein Maria A MA Department of Psychology, Washington State University, Pullman, WA, 99164-4820. - - 2014
Frontal EEG asymmetry patterns represent markers of individual differences in emotion reactivity and regulation, with right hemisphere activation linked with withdrawal behaviors/emotions (e.g., fear), and activation of the left hemisphere associated with approach (e.g., joy, anger). In the present study, gender was examined as a potential moderator of links between ...
Grupp Thomas M TM Aesculap AG Research & Development,Tuttlingen, Germany; Ludwig Maximilians University Clinic for Orthopaedic Surgery, Campus Grosshadern, Munich, Germany. Electronic address: - - 2014
The objective of our study was to evaluate the influence of prolonged artificial ageing on oxidation resistance and subsequent wear behaviour of vitamin E stabilised in comparison to standard and highly cross-linked, remelted polyethylene, and the degradation effect of third-body particles on XLPE inlays in total hip arthroplasty. Hip wear ...
Vaz-de-Lima Lourdes R A LR Immunology Center, Bacteriology Center, Instituto Adolfo Lutz, São Paulo, SP., - - 2014
Pertussis remains an important public health problem in many countries despite extensive immunization. Culture and real-time PCR (RT-PCR) assays are the recommended pertussis diagnostic tests but lack sensitivity at the later stage of disease. This study introduces the IgG anti-pertussis toxin ELISA (PT-ELISA) in our routine diagnosis to improve disease ...
Paloniemi Minna M Vaccine Research Center, University of Tampere, Biokatu 10, FM 3, 33520, Tampere, Finland, - - 2014
Human bocaviruses (HBoVs) may be grouped into respiratory (HBoV1) and enteric (HBoV2-4) types. We examined this association of HBoV types and clinical symptoms in 955 children who had acute gastroenteritis (AGE, n = 172), acute respiratory tract infection (ARTI, n = 545) or symptoms of both (n = 238). Both nasal swab and stool specimens were ...
Saif-Ur-Rehman Department of Pathology, Foundation University Medical College, - - 2014
Objective: To evaluate the presence of intrinsic factor antibody in vitamin B12 deficient patients. Study Design: Cross-sectional, observational study. Place and Duration of Study: Fauji Foundation Hospital, Foundation University Medical College and Armed Forces Institute of Pathology, Rawalpindi, from January 2011 to June 2012. Methodology: A total of 120 patients ...
Kolawole Olatunji Mathew OM Department of Microbiology, Infectious Diseases and Environmental Health Research Group, University of Ilorin, Ilorin, Kwara State, - - 2014
Infection of mothers with Rubella virus during pregnancy can be serious; if the mother is infected within the first 20 weeks of pregnancy she is likely to have miscarriage, stillbirth, or baby with congenital rubella syndrome. This study was carried out to define Rubella virus seroprevalence in pregnancy in Osogbo, ...
Tzu Jonathan H JH Bascom Palmer Eye Institute, University of Miami Miller School of Medicine , Miami, FL , USA - - 2014
Abstract Purpose: To phenotypically and genotypically characterize a large Puerto Rican kindred with X-linked retinitis pigmentosa associated with a novel RP GTPase regulator (RPGR) genotype. Methods: A total of 100 family members of a single kindred with X-linked RP were evaluated with ophthalmic examinations and blood DNA analysis. Visual fields, ...
Savage Mary J MJ Department of Molecular Biomarkers, Department of Neuroscience, and Department of Pharmacology, Merck & Company, Inc., West Point, Pennsylvania - - 2014
A hallmark of Alzheimer's disease (AD) brain is the amyloid β (Aβ) plaque, which is comprised of Aβ peptides. Multiple lines of evidence suggest that Aβ oligomers are more toxic than other peptide forms. We sought to develop a robust assay to quantify oligomers from CSF. Antibody 19.3 was compared ...
Elliott Jane J Centre for Longitudinal Studies, Institute of Education, 20 Bedford Way, London WC1H 0AE, UK. Electronic address: - - 2014
There is now a body of evidence that demonstrates strong links between neighbourhood characteristics and mental health and wellbeing. There is an increasing interest in how this relationship varies for individuals of different ages. Understanding the link between neighbourhood and wellbeing for older adults is of particular significance, given the ...
Gallucci Maurizio M 9 FORGEI, Interdisciplinary Geriatric Research Foundation, Treviso - - - 2014
<title>ABSTRACT</title><p><italic>Introduction:</italic> It has been reported that elderly subjects have a compromised ability to produce melatonin nightly, and that reduced melatonin levels may be a risk factor for cancer. The purpose of this study was to evaluate the relationship between melatonin levels and chronic diseases in a cohort of elderly subjects ...
Köse Sükran S Tepecik Educational and Research Hospital, Infectious Diseases and Clinical Microbiology, Allergy and Immunology Clinic, Izmir, - - 2014
The aim of the present study is to determine the prevalence of allergic diseases and related risk factors in Izmir, Turkey, and to assess the positive immunoglobulin E (IgE) levels against common allergens. The questionnaires were completed via face-to-face interview with a total of 2937 individuals. Specific IgE was studied ...
Cardarelli Roberto R University of Kentucky College of Medicine, Lexington, KY, - - 2014
Hypogonadism is highly prevalent in men older than 45 years and is associated with an increased risk of chronic diseases, including obesity, metabolic syndrome, diabetes, and cardiovascular disease. The objective of this study was to determine whether lifestyle factors such as smoking, diet, and exercise are associated with reduced testosterone ...
Espaldon Roxanne R Division of Geriatrics, University of California, San Francisco, San Francisco VA Medical Cente, San Francisco, - - 2014
To determine the distribution of screening prostate-specific antigen (PSA) values in older men, and how different PSA thresholds affect the proportion of white, black, and Latino men who would have an abnormal screening result across advancing age groups. We used linked national Veterans Affairs and Medicare data to determine the ...
Angaswamy N N Department of Surgery, Washington University School of Medicine, St. Louis, - - 2014
Antibodies (Abs) to donor HLA (donor-specific antibodies [DSA]) have been associated with transplant glomerulopathy (TG) following kidney transplantation (KTx). Immune responses to tissue-restricted self-antigens (self-Ags) have been proposed to play a role in chronic rejection. We determined whether KTx with TG have immune responses to self-Ags, Collagen-IV (Col-IV) and fibronectin ...
Shinkov A A Clinic of Thyroid and Bone Mineral Diseases, University Hospital of Endocrinology, Medical University of Sofia, 2 Zdrave St, 13th Floor, Sofia, 1431, Bulgaria, - - 2014
Anti-thyroid antibodies and thyroid ultrasound (US) are currently the methods for diagnosing autoimmune thyroid disease. Few data exist on their utility in males. The aim of the study was to investigate the gender-specific relationship between the Anti-TPO levels, thyroid ultrasound features, and thyroid function in a population with no known ...
Garay Ivonne I Division of Oral and Maxillofacial Radiology, Universidad de La Frontera - - 2014
The aim of this research is to determine the prevalence of soft tissue calcifications detectable on panoramic radiographs, in the mandibular angle area. 3,028 digital panoramic radiographs taken between June 2009 and June 2011 were evaluated. Soft tissue calcifications found in the mandibular angle area were recorded according to gender, ...
Sherwani Subuhi S Cardiff University School of Medicine, Institute of Infection and Immunity/Medical Microbiology, Cardiff, United - - 2014
Molluscum contagiosum virus (MCV) is a significant but underreported skin pathogen for children and adults. Seroprevalence studies can help establish burden of disease. Enzyme linked immunosorbent assay (ELISA) based studies have been published for Australian and Japanese populations and the results indicate seroprevalences between 6 and 22 percent in healthy ...
Brown Julie J a Neuroscience Research Australia , University of New South Wales , Randwick , New South Wales , - - 2014
Objective: To compare the pattern of injuries to front and rear seat occupants and test the hypothesis that rear seat passengers of different ages sustain different patterns of injury. Method: Patients admitted to a hospital following involvement in a crash in New South Wales (NSW) Australia between 2005 and 2007 ...
Diop Fode - - 2014
Programmes of pre-elimination of malaria have been implemented in Senegal since 2010, and the burden of malaria has decreased substantially. These changes in the epidemiology should be monitored with effective tools that allow changes in patterns of transmission to be estimated. In Dielmo and Ndiop, two villages of Senegal with ...
Ashaie Sameer S Speech-Language-Hearing Sciences, CUNY Graduate Center, 365 Fifth Avenue, New York City, NY 10016, - - 2014
We investigated the effects of age as well as the linked factors of education and bilingualism on confrontation naming in rural Kashmir by creating a culturally appropriate naming test with pictures of 60 objects. We recruited 48 cognitively normal participants whose ages ranged from 18 to 28 and from 60 ...
Xiong Geng G Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, P.R. - - 2014
Epstein-Barr Virus (EBV) is a globally prevalent herpesvirus associated with infectious mononucleosis and many malignancies. The survey on EBV prevalence appears to be important to study EBV-related diseases and determine when to administer prophylactic vaccine. The purpose of this retrospective study was to collect baseline information about the prevalence of ...
Wang Hai-Bo HB Expanded Program on Immunization, Chinese Center for Disease Control and Prevention, Beijing, - - 2014
After being polio free for more than 10 years, an outbreak following importation of wild poliovirus (WPV) was confirmed in Xinjiang Uygur Autonomous Region, China, in 2011. A cross-sectional study was conducted prior to supplementary immunization activities (SIAs), immediately after the confirmation of the WPV outbreak. In selected prefectures, participants ...
Karki S S Department of Veterinary Integrative Biosciences, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX, USA; Department of Livestock Services, Kathmandu, - - 2013
Kathmandu, Nepal has been classified as a high-risk area for highly pathogenic avian influenza (HPAI) by the Nepali Government. While ducks have an important role in the transmission of avian influenza viruses (AIV), including HPAI, seroprevalence of antibodies to AIV in domestic ducks of Kathmandu has never been assessed. The ...
Tomita Tetsu T Department of Neuropsychiatry, Graduate School of Medicine, Hirosaki University, Hirosaki, - - 2013
Background and Aim: Personality traits and vascular endothelial growth factor (VEGF) levels are both independently correlated with major depressive disorder and depressive mood. However, no studies have reported associations between personality traits and VEGF levels. Thus, we hypothesized that there is a correlation between the results of the Temperament and ...
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