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Csermely Gyula G RMC Fetal Medicine Center, Budapest, - - 2014
Multiple congenital abnormalities are caused by chromosomal aberrations, mutant major genes and teratogens. A minor proportion of these patients are identified as syndromes but the major part belonging to the group of unclassified multiple CAs (UMCAs). The main objective of this study was to evaluate the maternal age and birth ...
Paccou J J Department of Rheumatology, Amiens University Medical Center, F-80054 Amiens; - - 2014
Context: Recent data indicate that the secreted glycoprotein sclerostin may be involved in vascular calcification (VC). Objective: To establish whether serum sclerostin levels are associated with VC in patients with rheumatoid arthritis (RA). Design: Cross-sectional study. Setting: Ambulatory care. Patients: We compared 75 RA patients with 75 age- and gender-matched ...
Lally Lindsay L Department of Rheumatology, Hospital for Special Surgery, Department of Medicine, Weill-Cornell Medical College, Autoimmunity and Inflammation Program, Hospital for Special Surgery and Department of Clinical Pathology and Laboratory Medicine, Weill-Cornell Medical College, New York, NY, USA. Department of Rheumatology, Hospital for Special Surgery, Department of Medicine, Weill-Cornell Medical College, Autoimmunity and Inflammation Program, Hospital for Special Surgery and Department of Clinical Pathology and Laboratory Medicine, Weill-Cornell Medical College, New York, NY, USA. - - 2014
Aberrant rho kinase (ROCK) activity is implicated in the pathogenesis of several vascular diseases and is associated with Th17 differentiation. Th17 immune response is recognized in the pathogenesis of GCA. The aim of this study was to assess ROCK activity in GCA. All patients who underwent temporal artery biopsy (TAB) ...
Koga Monji M Department of Dermatology, Faculty of Medicine, Fukuoka University, Fukuoka, - - 2014
Neurofibromatosis type 1 (NF1) is a well-known genetic disorder characterized by café-au-lait spots and neurofibromas, but many other clinical characteristics and associated comorbidities also have been reported. This study aimed to characterize NF1 further by investigating its association with anthropometric characteristics and other diseases. We performed a case-control study of ...
Sanches Vinicius S VS Biological and Health Sciences Centre, Federal University of Mato Grosso do Sul, Campo Grande, Mato Grosso do Sul, - - 2014
Respiratory muscle strength (RMS) is a determinant of vital capacity, and its decline can lead to inadequate ventilation and deficiency in the elimination of secretions from the airways. Studies analyzing RMS in older adults with Parkinson's disease (PD) and Alzheimer's disease (AD) remain scarce, making the analysis of this variable ...
Goh Liang Kee LK Centre for Quantitative Medicine, Duke-NUS Graduate Medical School, Singapore, - - 2014
We previously reported TOMM40 to be significantly down-regulated in whole blood of Alzheimer's disease (AD) subjects at baseline and after one-year. In this longitudinal follow-up study of TOMM40 expression up to 2 years, we performed 6-monthly assessments for the first year and 2nd year blood sampling on 27 probable AD ...
Friesema I H M IH Centre for Infectious Disease Control, National Institute for Public Health and the Environment (RIVM),Bilthoven,The - - 2014
SUMMARY Shiga toxin-producing Escherichia coli (STEC) infections have been associated with severe illness. Ruminants are seen as the main reservoir and the major transmission route is considered to be foodborne. In The Netherlands, a case-control study was conducted, using data collected during 2008-2012. Patients were interviewed and controls completed a ...
Kaczynski Andrew T AT Department of Health Promotion, Education and Behavior, Prevention Research Center, Arnold School of Public Health, University of South Carolina, 915 Greene Street, Room 529, Columbia, SC 29208. Electronic address: - - 2014
To examine the potential efficacy of using point-of-decision prompts to influence intentions to be active in a park setting. In June 2013, participants from across the U.S. (n=250) completed an online experiment using Amazon's Mechanical Turk and Survey Monkey. Participants were randomly exposed to a park photo containing a persuasive, ...
Huang Lvzhen L Department of Ophthalmology, Peking University People's Hospital, Beijing, PR - - 2014
Purpose: rs1999930 and rs4711751 have recently been identified as novel variants associated with advanced age-related macular degeneration (AMD) in populations of European ancestry. We aimed to investigate whether these two single nucleotide polymorphisms (SNPs) were associated with neovascular AMD (nAMD) or with polypoidal choroidal vasculopathy (PCV), a variant of AMD ...
Sapir Amir A Division of Biology and Biological Engineering and Howard Hughes Medical Institute, California Institute of Technology, Pasadena, CA - - 2014
Many metabolic pathways are critically regulated during development and aging but little is known about the molecular mechanisms underlying this regulation. One key metabolic cascade in eukaryotes is the mevalonate pathway. It catalyzes the synthesis of sterol and nonsterol isoprenoids, such as cholesterol and ubiquinone, as well as other metabolites. ...
Perl Rebecca R World Lung Foundation, New York, New York, - - 2014
This study examined whether adaptation of existing antitobacco television and radio advertisements (ads) from high-income countries is a viable tobacco control strategy for Africa. 1078 male and female adult smokers and non-smokers, aged 18-40 years, from major and smaller urban locations in Kenya, Nigeria and Senegal, were recruited into groups using ...
Bertho Marie M Department of Psychology, EA4556, University Paul Valéry, Montpellier 3, Route de Mende, 34199 Montpellier Cedex 5, - - 2014
This article reports grammatical judgment data from eighteen French Williams syndrome (WS) (mean CA=21.10; Mean MA=11.2). Participants had to detect ungrammatical sentences (13 amongst a set of 26 sentences) in telling whether a given sentence was well said or not. Agrammaticality could be due to errors in tense, person agreement, ...
McMahon Emma J EJ Centre for Dietetics Research, School of Human Movement Studies, University of Queensland, St Lucia, QLD, Australia, 4067; Nutrition and Dietetics Department, Princess Alexandra Hospital, 199 Ipswich Road, Woolloongabba, QLD, Australia, 4102. Electronic address: - - 2014
Taste abnormalities are prevalent in Chronic Kidney Disease (CKD) potentially affecting food palatability and intake, and nutrition status. The TASTE CKD study aimed to assess taste and explore the relationship of dietary sodium intake with taste disturbance in CKD subjects. This was a cross-sectional study of 91 adult stage 3-5 ...
Goldstein Jesse A JA Philadelphia, Pa. From the Division of Plastic Surgery, Perelman School of Medicine at the University of Pennsylvania, Children's Hospital of - - 2014
The spheno-occipital synchondrosis is an important driver of facial and cranial base growth. The current study characterizes its fusion in patients with Apert, Crouzon, and Pfeiffer syndromes and correlates early fusion with the presence, and degree, of midface hypoplasia. A retrospective case-control study was performed of all syndromic patients treated ...
Moitra S S Molecular Respiratory Research Laboratory, Chest Research Foundation, Pune, - - 2014
Manual cigarette lighter refilling with butane/propane admixed liquefied petroleum gas (LPG) is a common low-income occupation in India. This practice may cause adverse health effects from LPG exposure among such workers. To assess respiratory status among LPG-exposed workers and non-exposed controls. We quantified the exposure and evaluated respiratory symptoms and ...
Siwek Marcin M Department of Affective Disorders, Chair of Psychiatry, Collegium Medicum, Jagiellonian University, Cracow, - - 2014
We investigated temperamental dimensions of the Temperament Evaluation of Memphis, Pisa and San Diego Autoquestionnaire (TEMPS-A) as well as bipolarity features in male and female subjects engaging in extreme or/and high risk sports. The web-based case-control study was performed in 480 subjects engaging in extreme or/and high risk sports (255 ...
Jäncke Lutz L Division Neuropsychology, Institute of Psychology, University of Zurich, Switzerland; Center for Integrative Human Physiology, University of Zurich, Switzerland; International Normal Aging and Plasticity Imaging Center (INAPIC), University of Zurich, Switzerland; University Research Priority Program (URPP) "Dynamics of Healthy Aging", University of Zurich, Switzerland; Department of Special Education, King Abdulaziz University, Jeddah, Saudi - - 2014
This study was conducted to examine the statistical influence of brain size on cortical, subcortical, and cerebellar compartmental volumes. This brain size influence was especially studied to delineate interactions with Sex and Age. Here, we studied 856 healthy subjects of which 533 are classified as young and 323 as old. ...
Lautner Ronald R Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg and Mölndal, - - 2014
Several studies suggest that the apolipoprotein E (APOE) ε4 allele modulates cerebrospinal fluid (CSF) levels of β-amyloid 42 (Aβ42). Whether this effect is secondary to the association of the APOE ε4 allele with cortical Aβ deposition or whether APOE ε4 directly influences CSF levels of Aβ42 independently of Aβ pathology ...
Duval Camille C School of Psychology and Neuroscience, University of St Andrews, Westburn Lane, St Andrews, Fife, KY169JP, United Kingdom. Electronic address: - - 2014
Physiological constraints on colouration have been widely reported; especially in birds, which trade-off antioxidant responses against colourful costly signals. One female extended phenotypic trait, which might also highlight important physiological trade-offs, is the pigmentation of their eggshells. In ground-nesting species, producing eggs that are visually undetectable by predators is the ...
Bohrer B M BM Department of Animal Sciences, The Ohio State University, Columbus, OH - - 2014
Objectives were to evaluate the administration of an anti-gonadotropin releasing factor (GnRF) analog on suppression of estrus, consistency of feed intake, and growth performance in market gilts; and, to investigate the impact the physiological changes would have on carcass characteristics and fresh meat quality. Gonadotropin releasing factor stimulates the anterior ...
Neira Marco M Oxitec Ltd, Oxford, - - 2014
Traditional mosquito control strategies rely heavily on the use of chemical insecticides. However, concerns about the efficiency of traditional control methods, environmental impact and emerging pesticide resistance have highlighted the necessity for developing innovative tools for mosquito control. Some novel strategies, including release of insects carrying a dominant lethal gene ...
Steinberg N N Anatomy and Anthropology, Sackler Faculty of Medicine, Tel-Aviv University, Tel Aviv, - - 2014
Very little is known about the relationship between proximal joint alignment and hallux valgus among young dancers. This study sought to determine the extent to which spinal and lower extremity alignments are involved in hallux valgus, and to identify predicting variables for its development in young dancers. A group of ...
Someeh Marjan M Department of Physical Education and Sport Sciences, University of Guilan, Rasht, - - 2014
To determine whether fibular repositioning tape influenced the postural control performance in athletes with and without chronic ankle instability (CAI). Research laboratory. A cross-sectional study, within subjects experimental study design between 4 ankle conditions (taped and untaped: CAI and healthy athletes). Sixteen volunteer professional athletes with unilateral CAI (10 men ...
Savaya Alkalay Amit A Department of Life Sciences and the National Institute for Biotechnology in the Negev, Ben-Gurion University, Beer Sheva, Israel; French Associates Institute for Agriculture and Biotechnology of Drylands, Jacob Blaustein Institute for Desert Research, Ben-Gurion University, Sede-Boqer, - - 2014
Early malacological literature suggests that the outbreak of schistosomiasis, a parasitic disease transmitted by aquatic snails, in the Senegal River basin occurred due to ecological changes resulting from the construction of the Diama dam. The common treatment, the drug praziquantel, does not protect from the high risk of re-infection due ...
Nielsen Philip Rising PR National Centre for Register-Based Research, iPSYCH, Aarhus University, Aarhus, Denmark; Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Aarhus University, Aarhus, Denmark. Electronic address: - - 2014
There is a long-standing interest in investigating the impact of early-life immune abnormalities on later onset of psychosis. The aim of this study was to assess inflammatory marker levels in neonatal dried blood spots and their association with later risk of schizophrenia. This nested case-control study included 995 cases and ...
Liu Guanmin G 1 Department of Psychology Tsinghua University, Beijing, - - 2014
Summary.-The goal was to examine whether visuomotor control and choice response time shared age-related developmental trajectories, and if prior computer experience played an important role in control processes. Children (6-7, 8-9, 10-11 yr.), younger adults (24 yr.) and older adults (76 yr.) performed the cursor pointing and choice response time ...
Ostovaneh Mohammad Reza MR Digestive Diseases Research Institute (DDRI), Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran. - - 2014
So far, a variety of prevalence rates have been reported for the metabolic syndrome (MetS) according to several definitions. The aim of this study was to assess the prevalence of MetS in Iran according to two definitions and compare the characteristics of the subjects who met the MetS criteria according ...
Gates Allison A School of Public Health & Health Systems, University of Waterloo, Waterloo, Ontario, Canada. - - 2014
Research investigating the body weight perceptions and eating-related weight control behaviors of First Nations (FN) youth living on reserve in Canada has been scarce. Knowledge of body weight perceptions may help to improve the relevance of initiatives promoting healthy weights. The purpose of this study was to examine the body ...
Hsieh Chang-Hsun CH Division of Endocrinology and Metabolism, Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei, - - 2014
The relationship between metabolic syndrome (MetS) and uric acid (UA) has been explored in many studies, but there is paucity of information on hypo-uricemia and MetS. The current study aimed to elucidate the relationship between the lower end of UA and MetS in elderly. Subjects aged ≥60 years who underwent routine ...
Jepsen Randi R Faculty of Health Studies, Sogn og Fjordane University College , Førde , Norway ; Department of Global Public Health and Primary Care, University of Bergen , Bergen , - - 2014
Objective. This study of severely obese adults participating in a two-year lifestyle intervention investigates associations between the independent variables: change in self-efficacy for physical activity (PA) in the face of psychological barriers, perceived behavioural control over PA, and PA self-identity and the dependent variable of change in objectively assessed PA. ...
Vitlic Ana A School of Sport, Exercise and Rehabilitation Sciences, University of Birmingham, Birmingham, UK ; MRC-Arthritis Research UK Centre for Musculoskeletal Ageing Research, University of Birmingham, Birmingham, - - 2014
The effect of the chronic stress of bereavement on immunity is poorly understood. Previous studies have demonstrated negative effects on immunity in older adults, and those who report higher depressive symptoms. The aim of the present study was to compare the effect of bereavement on neutrophil function in healthy young ...
Forbes Sean C SC Department of Physical Therapy, University of Florida, Gainesville, FL, United States of - - 2014
Duchenne muscular dystrophy (DMD) is an X-linked recessive disorder that results in functional deficits. However, these functional declines are often not able to be quantified in clinical trials for DMD until after age 7. In this study, we hypothesized that 1H2O T2 derived using 1H-MRS and MRI-T2 will be sensitive ...
Meo Sultan Ayoub SA Department of Physiology, College of Medicine, King Saud University, P.O. Box 2925, Riyadh 11461 Saudi Arabia. - - 2014
Shisha (waterpipe) smoking is becoming a more prevalent form of tobacco consumption, and is growing worldwide, particularly among the young generation in the Middle East. This cross-sectional study aimed to determine the effects of shisha smoking on lung functions and Fractional Exhaled Nitric Oxide (FeNO) among Saudi young adults. We ...
Croarkin Paul E PE Division of Child and Adolescent Psychiatry, Department of Psychiatry and Psychology, Mayo Clinic Rochester, MN, - - 2014
The objective of this post-hoc exploratory analysis was to examine the relationship between age and measures of cortical excitability and inhibition. Forty-six participants (24 with major depressive disorder and 22 healthy controls) completed MT, SICI, ICF, and CSP testing in a cross-sectional protocol. Of these 46 participants, 33 completed LICI ...
Hosseinpanah Farhad - - 2013
To evaluate diagnostic accuracy of lipid accumulation product(LAP) index as a marker of insulin resistance in a community based population with polycystic ovary syndrome(PCOS), compared to healthy women. Anthropometric measurements, biochemical parameters, LAP index and insulin resistance(IR) were compared in 134 PCOS subjects and 414 healthy women recruited from 1126 ...
Kalkwarf Heidi J HJ Division of General and Community Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA. - - 2013
Little is known about factors that affect bone mass and density of infants and toddlers and the means to assess their bone health owing to challenges in studying this population. The objectives of this study were to describe age, sex, race, growth, and human milk feeding effects on bone mineral ...
Mostoufi-Moab Sogol - - 2012
Children with acute lymphoblastic leukemia (ALL) are at risk for impaired bone accrual. This peripheral quantitative computed tomography study assessed changes in bone mineral density (BMD) and structure after completion of ALL treatment. Fifty ALL participants, ages 5-22 yr, were enrolled within 2 yr (median 0.8 yr) after completing ALL ...
Tsilimparis Nikolaos - - 2012
BACKGROUND: In the endovascular era, elderly patients are offered repair of their aortoiliac aneurysms (AAA) more frequently than in the past. Our objective is to compare age groups and draw inferences for AAA repair outcomes. STUDY DESIGN: We identified 20,095 patients who underwent AAA repair between 2005 and 2010 using ...
Villa Paola P University of Colorado Museum, Boulder, CO 80309-0265, USA. - - 2012
The transition from the Middle Stone Age (MSA) to the Later Stone Age (LSA) in South Africa was not associated with the appearance of anatomically modern humans and the extinction of Neandertals, as in the Middle to Upper Paleolithic transition in Western Europe. It has therefore attracted less attention, yet ...
Camhi Sarah M - - 2012
Physical activity (PA), total body fat (TBF), and lean body mass (LBM) are associated with bone mineral density (BMD). However, the independent influence of PA on BMD, while controlling for body composition is not understood as well and is the purpose of the current study. Whole-body BMD (g·cm(-2)), femoral neck ...
Tveit M - - 2012
This is a study on exercise-associated bone mineral density (BMD) which in men is maintained three decades after cessation of sports. In this prospective controlled cohort study active athletes had a BMD Z-score of 1.0 and after 39 years 0.5 to 1.2 depending on the measured region), using the same ...
Gu Sa-Sa - - 2012
The local tissue-specific renin-angiotensin system (RAS) was identified. The aim of this study was to investigate the role of local bone RAS in the osteoporosis of aging mice. Twelve-month-old and two-month-old male mice were respectively assigned to the ageing and young groups. The tibias and femurs were collected for an ...
Cheon Haengbok - - 2012
The aim of this study was to assess age-related changes and anatomic variation in trabecular bone mineral density (tBMD) using quantitative computed tomography (QCT) in normal cats. Seventeen normal cats were included in this study and divided into the following 3 age groups: <6 months (n=4); 2-5 years (n=10); and ...
Cipriani Cristiana - - 2012
The aim of this work was to examine the effects of age and menopause on muscle strength and on the muscle-bone interaction. One hundred ninety-four healthy women (mean age 49.8 ± 12.6 SD years) were assessed. Maximal Voluntary Contraction (MVC, Newton, N) by Hand Grip Dynamometer, bone mineral density at ...
Fuchs Deborah A - - 2012
Developmental differences in megakaryocytes between neonates and adults have been described. However, the age at which megakaryocytes make a transition to an adult phenotype is unknown. Small megakaryocytes are often described as "dysplastic" in the pathology literature. Thus, recognizing the normal features of megakaryocytes at different ages has diagnostic implications. ...
Gupta Neera - - 2012
BACKGROUND AND AIMS: The timing of menarche in Crohn's disease (CD) is poorly described. Our objectives were to study age at menarche onset in CD, and factors associated with this. METHODS: We compared the age at menarche of 34 CD patients with that for 545 controls, using data in the ...
Siminoski K K University of Alberta, 6628-123 Street, Edmonton, Alberta, Canada T6H 3T6. - - 2013
Bone mineral content (BMC) is known to be greater in the dominant arm after the age of 8 years. We studied a group of children and found that BMC sidedness gradually increased up to the age of 6 years and then remained stable into late adolescence. Bone mineral content (BMC) ...
Laakso Saila - - 2012
Previous studies have indicated that children with inflammatory bowel disease (IBD) may not achieve optimal bone mass. We evaluated the skeletal characteristics in children and adolescents with IBD. This cross-sectional cohort study comprised 80 IBD patients (median age 14.9 years, range 5-20) with a median disease duration of 3.4 years; 51 had ...
Liu Hen-Yu - - 2012
Adipose-derived stem cells (ADSCs) have been shown to be pluoripotent and explored for their usage in tissue engineering. Previously, we have established a cell-based approach comprised of platelet-enriched plasma and osteo-progenitor cells for treating osteoporosis in an ovariectomized-senescence-accelerated mice (OVX-SAMP8) model. In the present study, we intend to explore the ...
Parm Anna-Liisa - - 2012
Aim: Relationships between change of bone mineral density (BMD) and baseline adipocytokine and ghrelin levels over 12 months in prepubertal rhythmic gymnasts (RG) and age-matched untrained controls (UC) were studied. Methods: Adipocytokine, ghrelin, body composition, BMD and bone age values were measured in RG (8.0 ± 0.6 years; n = ...
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