Search Results
Results 1 - 50 of 887
1 2 3 4 5 6 7 8 9 10 >
Matsumoto Tomoyuki T Department of Orthopaedic Surgery, Kobe University Graduate School of Medicine, Kobe, Hyogo, Japan. Electronic address: - - 2014
This study aimed to investigate alignment based on age in normal knees and alignment based on deformity in osteoarthritis (OA) knees using detailed radiographic parameters. Various parameters were measured from weight-bearing long leg radiographs of 1251 legs (797 normal and 454 OA knees) as a cross-sectional study. Normal knees were ...
Machado Flavia S FS Division of Rheumatology (F.S.M., J.N., A.L.P.d.B., R.N.V.F.) and Department of Radiology (R.D.T.), Universidade Federal de São Paulo, Escola Paulista de Medicina, São Paulo, - - 2014
To describe quantitative and semiquantitative sonographic joint measurements in healthy adults and compare them with demographic parameters. A cross-sectional study was conducted. Bilateral sonographic measurements of small, medium, and large joints were performed in 130 healthy volunteers, stratified into 5 age groups (A, 18-29; B, 30-39; C, 40-49; D, 50-59; ...
Joghtaei Mahmoud - - 2014
Objective Stiffness and viscosity represent passive resistances to joint motion related with the structural properties of the joint tissue and of the musculotendinous complex. Both parameters can be affected in patients with spinal cord injury (SCI). The purpose of this study was to measure passive knee stiffness and viscosity in ...
Francuski J V JV Faculty of Veterinary Medicine, University of Belgrade, - - 2014
The aims of this study were to define age-related histological changes in the articular cartilage of the stifle joint in non-chondrodystrophic dogs and to determine whether physical activity has a positive impact on preservation of cartilage structure during ageing. Twenty-eight German shepherd dogs were included in the study. These dogs ...
Hiraga Masao M Kirishima Medical Center , Kirishima, Kagoshima , - - 2014
Introduction. Assessment of synovitis in the metatarsophalangeal (MTP) joints with ultrasound has been shown to improve the accuracy of assessment of rheumatoid arthritis (RA). However, the presence of intraarticular low-echoic synovial area (LESA) in the MTP joints in healthy subjects complicates the sonographic assessment of these joints. Method. Healthy subjects ...
Kulmala Juha-Pekka JP Department of Biology of Physical Activity, University of Jyväskylä, Viveca 223, Rautpohjankatu 8 A, 40014 Jyväskylän Yliopisto, Finland Agora Center, University of Jyväskylä, Viveca 223, Rautpohjankatu 8 A, 40014 Jyväskylän Yliopisto, Finland Department of Mechanical Engineering, Lappeenranta University of Technology, 53850 Lappeenranta, Finland - - 2014
Ageing leads to a progressive decline in human locomotor performance. However, it is not known whether this decline results from reduced joint moment and power generation of all lower limb muscle groups or just some of them. To further our understanding of age-related locomotor decline, we compare the amounts of ...
Conconi Michele M Health Sciences and Technologies, Interdepartmental Center for Industrial Research (HST-ICIR), Alma Mater Studiorum-University of Bologna, Bologna, Italy. Electronic address: - - 2014
Previous studies suggest that osteoarthritis (OA) is related to abnormal or excessive articular contact stress. The peak pressure resulting from an applied load is determined by many factors, among which is shape and relative position and orientation of the articulating surfaces or, referring to a more common nomenclature, joint congruence. ...
Park Yongnam Y Department of Physical Therapy, Daewon College, Republic of - - 2014
[Purpose] The purpose of this study was to identify postural changes in adults who have adopted the habit of sitting with their legs crossed. [Subjects and Methods] The subjects were 232 adults in their 20s and 30s (84 males and 148 females). They were divided into 0-, 1-, 2-, and ...
Caglar E E Department of Radiology, Ankara Oncology Research and Education Hospital, Ankara, Turkey. - - 2014
To identify changes in knee joint cartilage transverse relaxation values depending on the patient's age and gender and to investigate the relationship between knee joint pathologies and the transverse relaxation time. Knee MRI images of 107 symptomatic patients with various pathologic knee conditions were analyzed retrospectively. T2 values were measured ...
Kumar Deepak D Musculoskeletal Quantitative Imaging Research Group, Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, - - 2014
Study Design Cross-sectional design. Objectives To investigate association of knee loading related osteoarthritis (OA) risk factors (obesity, malalignment, physical activity), with medial knee laminar (superficial and deep) T1rho and T2 relaxation times. Background Interaction of various modifiable loading related knee risk factors and cartilage health in knee OA is currently ...
Menz H B HB Arthritis Research UK Primary Care Centre, Research Institute for Primary Care and Health Sciences, Keele University, Keele, Staffordshire, ST5 5BG, United Kingdom; Lower Extremity and Gait Studies Program, School of Allied Health, La Trobe University, Bundoora, Victoria 3086, Australia. Electronic address: - - 2014
To explore demographic and clinical factors associated with radiographic severity of first metatarsophalangeal joint osteoarthritis (OA) (First MTPJ OA). Adults aged ≥50 years registered with four general practices were mailed a Health Survey. Responders reporting foot pain within the last 12 months were invited to undergo a clinical assessment and ...
Celik Derya D Division of Physiotherapy and Rehabilitation, Faculty of Health Sciences, Istanbul University, Istanbul, - - 2014
Study Design Clinical measurement. Objective To translate and culturally adapt the International Knee Documentation Committee (IKDC) Subjective Knee Form into Turkish and to determine selected psychometric properties of the translated version. Background The IKDC Subjective Knee Form is widely used to evaluate disability associated with knee injuries, but it has ...
Xia Bingjiang B Shaoxing Hospital of Traditional Chinese Medicine, Shaoxing, 312000, Zhejiang, - - 2014
Osteoarthritis (OA), the most prevalent chronic joint disease, increases in prevalence with age, and affects majority of individuals over the age of 65 and is a leading musculoskeletal cause of impaired mobility in the elderly. Because the precise molecular mechanisms which are involved in the degradation of cartilage matrix and ...
Arzi B B Department of Surgical and Radiological Sciences, School of Veterinary Medicine, University of California, Davis, CA 95616, USA. Electronic address: - - 2015
Following comprehensive characterization of the temporomandibular joint (TMJ) of the California sea lion, as well demonstrating that TMJ-osteoarthritis (OA) occurs in this species, the objective of this part of the investigation was to describe the macroscopic osteologic findings associated with TMJ-OA in a large museum collection of skull specimens. Museum ...
Harrington Katherine I KI Department of Anthropology, Texas State University, San Marcos, TX, - - 2014
This study tests for differences in articular and diaphyseal size and shape of the distal femur and proximal tibia between normal weight and obese individuals, and discusses the effects of obesity on the patterns of sexual dimorphism and secular change in the skeletal morphology of the knee. Measurements of the ...
Marwan Yousef Abbas YA *Division of Orthopaedic Trauma, Department of Orthopaedic Surgery, Al-Razi Orthopaedic Hospital, Kuwait City, Kuwait †Department of Radiology, Al-Amiri Hospital, Kuwait City, Kuwait ‡Department of Radiology, Faculty of Medicine, Health Sciences Center, Kuwait University, Kuwait City, Kuwait §Division of Orthopaedic Surgery, Department of Surgery, Faculty of Medicine, Health Sciences Center, Kuwait University, Kuwait City, Kuwait; and ¶Department of Radiology, Mansoura University, Mansoura, - - 2014
Cross-sectional, retrospective. To identify morphological and morphometric features of the coccyx among adult Arabs. Different sacrococcygeal morphologic features were found to be associated with coccydynia. Review of 202 computed tomographic scans of adult Arab subjects was done (mean age: 47.98 ± 16.46 yr). Sacrococcygeal morphological features including number of coccygeal ...
Quinzi Federico F Laboratory of Exercise Physiology, Division of Human Movement and Sport Sciences, Department of Movement, Human and Health Sciences, University of Rome "Foro Italico", Piazza Lauro de Bosis 6, 00135, Rome, Italy, - - 2014
Age-related neuromuscular control adaptations have been investigated mainly in untrained populations, where higher antagonist activation in adults was observed with respect to children. In elite athletes age-related differences in neuromuscular control have scarcely been investigated. Therefore, this study aims at investigating differences in co-activation about the knee joint in two ...
Kitchen Joanne J Department of Rheumatology, Adelaide & Meath Hospital Dublin Incorporating the National Children's Hospital, Tallaght, Dublin, Ireland. - - 2014
US is a promising tool in evaluating RA synovitis, but abnormal US findings have been reported in small subsets of normal joints in healthy subjects. This study aimed to systematically assess greyscale US (GSUS) and power Doppler US (PDUS) findings in 40 peripheral joints-the 28-joint DAS (DAS28) set, ankles and ...
Yanagisawa Shinya S Department of Orthopaedic Surgery, Gunma University Graduate School of Medicine, Gunma, - - 2014
The aim of this study was to evaluate the medial aspect of the knee with ultrasound (US). This study included 71 men and 154 women (450 knees) with a mean age of 65 years. US was used to evaluate the medial joint space of both knees with and without weight-bearing. ...
Kapetanovic Meliha C MC Department of Clinical Sciences Lund, Section of Rheumatology, Lund University and Skåne University Hospital, - - 2014
Objectives. To study the course of impairment measured by signals of functional impairment (SOFI) and disability measured by health assessment questionnaire (HAQ) over 20 years in rheumatoid arthritis (RA) patients followed from diagnosis. To explore the contribution of disease activity, joint damage and comorbidity to variation of SOFI and HAQ ...
Mouton Caroline C Sport Medicine Research Laboratory, Public Research Center for Health, Luxembourg, - - 2014
The aim of this study was to quantify sagittal and rotational knee laxity profiles taking into account individual influencing factors. Linear regression models were used to determine which individual characteristics (age, height, body mass and sex) influenced the outcome in a group of 104 healthy subjects. The standardized residuals were ...
Bae Kee Jeong KJ Department of Orthopedic Surgery, Seoul National University Boramae Medical Center, Seoul, - - 2014
Reports on the relationship between osteoporosis and osteoarthritis (OA) have tended to disagree, especially in non-weight bearing joints such as the hand joints. We aimed to investigate the relationship between bone mineral density (BMD) and hand and knee OA in a general Korean elderly population. We evaluated femur neck BMD ...
Fu Zhe Z Department of Pediatric Orthopaedic, Tianjin Hospital, Tianjin, - - 2014
Untreated residual subluxation after early closed reduction for developmental dislocation of the hip (DDH) leads to early degenerative osteoarthritis. The aim of our study was to investigate the role of early surgical timing and its indications. Thirty-six patients (48 hips) with untreated residual subluxation after closed reduction who had serial ...
Milner Allison A Melbourne School of Population and Global Health, University of Melbourne, Melbourne, VIC, Australia, School of Public Health and Community Medicine, University of New South Wales, Sydney, NSW, Australia and School of Health and Social Development, Deakin University, Melbourne, VIC, Australia - - 2014
Suicide is higher among economically inactive and unemployed persons than employed persons. This paper investigates differences in this relationship by sex and age over the period 2001 to 2010 in Australia. It also examines changes in suicide among employed, unemployed and economically inactive persons during the recession of 2007-09. Suicide ...
Bucala Rick - - 2014
The inactivation of NO by advanced glycation endproducts (AGEs), which accumulate on tissue proteins as a function of age and hyperglycemia, focused attention on the role of these ubiquitous posttranslational modifications in acquired impairments of vascular reactivity and other signaling processes. This observation occurred during a watershed period of basic ...
Gratz Iris K IK Department of Dermatology, University of California San Francisco, San Francisco, CA - - 2014
Immune homeostasis in peripheral tissues is achieved by maintaining a balance between pathogenic effector T cells (Teffs) and protective Foxp3(+) regulatory T cells (Tregs). Using a mouse model of an inducible tissue Ag, we demonstrate that Ag persistence is a major determinant of the relative frequencies of Teffs and Tregs. ...
Baugé Catherine C Normandie Univ, France ; UNICAEN, EA4652 MILPAT, Caen, - - 2014
Transforming growth factor beta (TGFβ) is a major signalling pathway in joints. This superfamilly is involved in numerous cellular processes in cartilage. Usually, they are considered to favor chondrocyte differentiation and cartilage repair. However, other studies show also deleterious effects of TGFβ which may induce hypertrophy. This may be explained ...
Rtimi S - - 2013
This study reports the design, preparation, testing and surface characterization of uniform films deposited by sputtering Ag and Ta on non-heat resistant polyester to evaluate the Escherichia coli inactivation by TaON, TaN/Ag, Ag and TaON/Ag polyester. Co-sputtering for 120s Ta and Ag in the presence of N2 and O2 led ...
Alves Markênia Kélia Santos - - 2013
CDKN2A promoter hypermethylation has been widely related to many cancers. In astrocytomas, although CDKN2A (p16(INK4A) protein) is often inactivated, there are still some controversial issues regarding the mechanism by which this alteration occurs. Thus, we analyzed a series of astrocytomas to assess the association between CDKN2A expression and methylation of ...
Jin Jung Kyung - - 2013
The molecular inflammation hypothesis of aging proposes that redox dysregulation causes an age-related activation of NF-κB and its signaling to upregulate various proinflammatory genes. In the present study, we focused on the inactive form of the protein phosphastase 2A (PP2A). More specifically, we aimed to define the correlation between PP2A ...
Godler David E DE Cyto-molecular Diagnostic Research Laboratory, Victorian Clinical Genetics Services and Murdoch Childrens Research Institute, Royal Children’s Hospital, Melbourne, Victoria 3052, Australia. - - 2013
Methylation of the fragile X-related epigenetic element 2 (FREE2) located on the exon 1/intron 1 boundary of the FMR1 gene is related to FMRP expression and cognitive impairment in full mutation (FM; CGG>200) individuals. We examined the relationship between age, the size of the FMR1 CGG expansion and the methylation ...
Su Rina - - 2012
The objective of this study was to determine the bactericidal mechanisms of Ag-doped multi-walled carbon nanotube (MWCNT) nanoparticles (Ag(0)/MWCNTs) to Escherichia coli DH5α. The contributions of silver ion dissolution, reactive species, and direct contact on bacteria inactivation were systematically determined. The relatively higher survival rate of bacteria exposed to 0.02mgL(-1) ...
Cumurcu Tongabay - - 2012
PURPOSE: To evaluate the tear film function and ocular surface changes in heavily drinking men. METHODS: This prospective case-control study involved 35 male subjects with heavy alcohol consumption (group 1) and 35 age- and sex-matched control subjects (group 2). Best-corrected visual acuity measurement, slit-lamp examination, Schirmer I test, tear film ...
Ventura Maria Teresa - - 2012
The constant increase in the elderly population worldwide has led to a greater interest in immunologic responses during aging. Thus, special attention to allergic diseases in elderly people has begun to emerge, but little is known about the effect and features of allergic rhinitis in elderly people. To evaluate the ...
Xue Xia - - 2012
The whitefly Bemisia tabaci is cryptic species complex composed of numerous species. Individual species from the complex harbor a diversity of bacterial endosymbionts including Wolbachia. However, while Wolbachia is known to have a number of different roles, its role in B. tabaci is unclear. Here, the antibiotic rifampicin is used ...
Atalay Sacide S Department of Medical Biochemistry, Haydarpasa Numune Teaching and Research Hospital, Istanbul, Turkey. - - 2012
We aimed to investigate the diagnostic utility of osteocalcin (OC), undercarboxylated osteocalcin (ucOC), and alkaline phosphatase (ALP) in pre- and postmenopausal women for femoral neck, L1-4, and L2-4 bone mineral density (BMD) values by taking into consideration their age, body mass index (BMI), and menopausal status. Premenopausal (N=40) and postmenopausal ...
Marwaha Raman K - - 2011
We undertook this study to establish age-specified bone mineral density (BMD) reference range for Indian females using dual-energy X-ray absorptiometry. BMD at multiple skeletal sites was measured in 2034 healthy women aged 18-85yr. The effect of anthropometry and biochemical parameters on BMD was determined. Peak BMD was observed between 30 ...
Sun Yue - - 2011
Autosomal dominant hypophosphatemic rickets (ADHR; MIM 193100) is a hereditary disorder characterized by isolated renal phosphate wasting, hypophosphatemia, and inappropriately normal 1,25-dihydroxyvitamin D(3) levels. Recent studies have shown that the fibroblast growth factor 23 (FGF23) gene is responsible for this disease. FGF23 protein is a phosphaturic factor that is elevated ...
Perinetti Giuseppe - - 2011
Identification of skeletal maturation phases is of primary importance in terms of individual responsiveness to nearly all dentofacial orthopaedic treatments. In this regard, dentition phase and chronological age are still widely used to define the timing of and responsiveness to orthodontic treatments. Recently, gingival crevicular fluid (GCF) alkaline phosphatase (ALP) ...
Wong R W K - - 2011
Preliminary results were determined for a database on 3-dimensional (3D) cephalometrics using McNamara's analysis in an adult southern Chinese population based on cone-beam computerized tomography (CBCT). 3D dentoskeletal morphology was assessed from CBCTs from 80 (39 males; 41 females; 21-30 years) consecutive adult southern Chinese without gross craniofacial deformity or ...
Chen Wei-Yu - - 2011
The purpose of this study was to link toxicokinetics/toxicodynamics and subcellular partitioning for assessing the susceptibility and the growth inhibition risks of abalone Haliotis diversicolor supertexta exposed to waterborne and foodborne cadmium (Cd) and silver (Ag). We reanalyzed published data on growth inhibition and subcellular partitioning associated with the present ...
Agusa Tetsuro - - 2011
Body distribution and growth- and nutritional status-dependent accumulation of 21 trace elements were investigated in harbor seals (Phoca vitulina) stranded in the North Sea coast in 2002. Higher concentrations and burdens of Mn, Se, Mo, Ag, Sn, Hg, and Bi in the liver, Cd in the kidney, As in the ...
Storr Helen L - - 2011
Objective: There are few published comparisons between paediatric and adult-onset Cushing's disease (CD). We compare the epidemiology, diagnostic features and cure rate by transsphenoidal surgery (TSS) in these groups. Design: Retrospective review of patient databases in single university hospital centre. Patients: Forty-one paediatric (mean age 12.3±3.5 yr; range 5.7-17.8) and ...
Manteca Xavier - - 2011
With increasing age, some dogs develop a neurogenerative disease that is commonly referred to as canine cognitive dysfunction syndrome (CDS). Diagnosis of CDS can be clinical or based on laboratory tests. The main behavioral changes associated with CDS are disorientation, altered interactions with people or other animals, sleep-wake cycle alterations, ...
Mangat Birinder K BK Department of Medicine, University of British Columbia, Vancouver, British - - 2011
There is currently little available information regarding the impact of ethnicity on the clinical features of inflammatory bowel disease (IBD). Migrating populations and changing demographics in Vancouver, British Columbia (BC) provide a unique opportunity to examine the role of ethnicity in the prevalence, expression and complications of IBD. To determine ...
Gupta Neera N Department of Pediatrics, University of California, San Francisco, San Francisco, California 94143, USA. - - 2011
Growth impairment in Crohn's disease (CD) is more common in males than females for unknown reasons. Since insulin-like growth factor-1 (IGF-1) is important for statural growth, we hypothesized that IGF-1 levels are lower in males with CD. Sex differences in hormone Z-scores based on chronological age (CA-Z) and bone age ...
Devaney Joseph M JM Department of Integrative Systems Biology, Research Center for Genetic Medicine, Children’s National Medical Center, 111 Michigan Ave. NW, Washington, DC 20010, - - 2011
Converging lines of evidence suggest that AKT1 is a major mediator of the responses to insulin,insulin-like growth factor 1 (IGF1), and glucose. AKT1 also plays a key role in the regulation of both muscle cell hypertrophy and atrophy. We hypothesized that AKT1 variants may play a role in the endophenotypes ...
Hipfner J M - - 2011
In 2003 and 2004, we measured mercury concentrations and δ(15)N and δ(13)C values in the whole blood of adults of two species of seabirds, Cassin's auklet (Ptychoramphus aleuticus) and rhinoceros auklet (Cerorhinca monocerata), during their prelaying, incubation, and provisioning periods. We also collected whole blood from the offspring of both ...
Ferrari M - - 2011
To assess the iron status among European adolescents through selected biochemical parameters in a cross-sectional study performed in 10 European cities. Iron status was defined utilising biochemical indicators. Iron depletion was defined as low serum ferritin (SF<15 μg/l). Iron deficiency (ID) was defined as high-soluble transferrin receptor (sTfR>8.5 mg/l) plus ...
Pansuwan Anupong - - 2011
The prevalence of adolescent anemia, iron deficiency and thalassemia were examined in 2 provinces of northeast Thailand. Blood specimens were collected from adolescent subjects aged 15-17 years in 2 areas; 185 (85 males and 100 females) in Mukdahan province and 313 (116 males and 197 females) in Roi-Et. RBC parameters, ...
1 2 3 4 5 6 7 8 9 10 >