Search Results
Results 1 - 50 of 1236
1 2 3 4 5 6 7 8 9 10 >
Luo Ruxin R Shanghai Key Laboratory of Forensic Medicine, Institute of Forensic Science, Ministry of Justice, Shanghai 200063, - - 2014
Hair samples from 190 relatively healthy 20- to 98-year-old volunteers from a mountain village of Tonglu city (Zhejiang province, China) were analyzed to determine the contents of 33 chemical elements (Ag, Al, As, Au, B, Ba, Be, Ca, Cd, Co, Cr, Cs, Cu, Fe, Ga, Hg, Li, Mg, Mn, Mo, ...
Hecker Louise L Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294, - - 2014
The incidence and prevalence of pathological fibrosis increase with advancing age, although mechanisms for this association are unclear. We assessed the capacity for repair of lung injury in young (2 months) and aged (18 months) mice. Whereas the severity of fibrosis was not different between these groups, aged mice demonstrated ...
Reddy Gadi V P - - 2014
Pheromone dose, effective trapping distance, and longevity of the rubber septa loaded with sex pheromone of Cylas formicarius (F.) (Coleoptera: Brentidae) were evaluated for their impact on the efficacy of mass trapping of the insect in sweet potato fields in Guam in 2012-2013. The number of adults caught at different ...
Anderson Lindsay L Allan Wilson Centre for Molecular Ecology and Evolution, School of Biological Sciences, Victoria University of Wellington, P.O. Box 600, Wellington 6140, New Zealand. Electronic address: - - 2014
Baseline and stress response glucocorticoid (GC) secretion can be modulated by individuals to support activities and physiological functions connected with reproduction (migration, mating, oviposition and/or parturition, care of young). Corticosterone (CORT) is the primary GC in reptiles and, in accordance with other vertebrates, an adrenocortical stress response is observed. Modulation ...
Edrey Yael H YH The Sam and Ann Barshop Institute for Longevity and Aging - - 2014
Significant advances in maintaining health throughout life can be made through a clear understanding of the fundamental mechanisms that regulate aging. The Oxidative Stress Theory of Aging (OSTA) is likely the most well-studied mechanistic theory of aging and suggests that the rate of aging is controlled by accumulation of oxidative ...
Wenger Barbara - - 2014
Promyelocytic leukemia nuclear bodies (PML-NBs) have been depicted as structures which are involved in processing cell damages and DNA double-strand break repairs. The study was designed to evaluate differences in patients' PML-NBs response to stress factors like a cancerous disease and ionizing radiation exposure dependent on age. In order to ...
Lademann J J Centre of Experimental and Applied Cutaneous Physiology, Department of Dermatology, Venereology and Allergology, Charité - Universitätsmedizin Berlin, Berlin - - 2014
Carotenoids could serve as marker substances of the antioxidant status of the human skin. In the present study, an optical skin scanner was used to analyse the carotenoid concentration obtained from 4 volunteers over a period of 13 days. The measurements were taken daily at different time points. In addition, ...
Li Hongwei H State Key Laboratory of Plant Cell and Chromosome Engineering, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, No. 1 West Beichen Road, Chaoyang District, Beijing, 100101, - - 2014
The antioxidant system was significantly inhibited in the early aging line than the near-isogenic normal aging line during senescence. The antioxidant system plays pivotal roles in removal of reactive oxygen species (ROS) produced during leaf senescence. To explore its roles in leaf senescence of wheat (Triticum aestivum L.), the concentrations ...
Taylor C M CM Centre for Child and Adolescent Health, School of Social and Community Medicine, University of Bristol, UK. Electronic address: - - 2014
The aim of this study was to evaluate the effect of prenatal exposure to lead, cadmium and mercury levels on the secondary sex ratio. Whole blood samples were collected from pregnant women enrolled in the Avon Longitudinal Study of Parents and Children (ALSPAC) study at a median gestational age of ...
Schwarzer Caroline C C Schwarzer, Cell and Developmental Biology, Max Planck Institute for Molecular Biomedicine, Münster, 48149, - - 2014
The long-standing view of 'immortal germ line versus mortal soma' poses a fundamental question in biology concerning how oocytes age in molecular terms. A mainstream hypothesis is that maternal ageing of oocytes has its roots in gene transcription. Investigating the proteins resulting from mRNA translation would reveal how far the ...
Nakamura Masaaki M Department of Clinical Medicine, National Institute for Minamata Disease, Minamata, Japan. Electronic address: - - 2014
Methylmercury (MeHg) is a major environmental neurotoxicant that causes damage to the central nervous system. In Japan, industrial emission of MeHg has resulted in MeHg intoxication in Minamata and Niigata, the so-called Minamata disease. Humans are exposed to MeHg derived from natural sources, primarily fish and fish predators. Therefore, MeHg ...
Schaumburg Laura G LG Grupo de Investigación en Biología Evolutiva (GIBE), IEGEBA (CONICET-UBA), Labs. 43 y 46, Piso 4, FCEyN - Pabellón II - Cdad. Universitaria, Intendente Güiraldes 2160 (CP: 1428EGA) Buenos Aires, Argentina. Tel. (5411) 45763348 Int 261- Fax (5411) 4576-3354; Laboratorio Zoología Aplicada: Anexo Vertebrados (FHUC, UNL/MASPyMA), Aristóbulo del Valle 8700 (CP: 3000) Santa Fe, Argentina. Electronic address: - - 2014
Several studies indicate that certain factors such as age, sex or nutritional status among others, may affect the level of DNA damage, both induced and spontaneous, so it is very important to consider them for a more accurate interpretation of the findings. The aim of this study was to analyze ...
Mitzel Dana N DN Animal Biosafety Level 3 Management Support, Lovelace Respiratory Research Institute, Albuquerque, NM - - 2014
Pneumococcal infections remain a leading cause of death in persons ≥65 y of age. Recent reports have illustrated detrimental changes in the endoplasmic reticulum stress response or unfolded protein response in aging and age-related diseases; however, the relationship between aging, the unfolded protein response, and innate immune responses to Streptococcus ...
Lauhkonen Eero E Tampere Center for Child Health Research, Tampere University and University Hospital, Tampere, - - 2014
Viral bronchiolitis in infancy has been associated with increased bronchial reactivity and reduced lung function in later childhood and even in adulthood. However, lung function at preschool age is less studied, mainly due to technical difficulties. The purpose of the study was to evaluate lung function and bronchial reactivity at ...
Waaijer Mariëtte E C ME Department of Gerontology and Geriatrics, Leiden University Medical Center, 2300 RC, Leiden, The - - 2014
MicroRNAs, regulators of messenger RNA translation, have been observed to influence many physiological processes, amongst them the process of aging. Higher levels of microRNA-663 (miR-663) have previously been observed in human dermal fibroblasts subject to both replicative and stress-induced senescence compared to early passage cells. Also, higher levels of miR-663 ...
Yount Kathryn M KM Asa Griggs Candler Chair of Global Health, Hubert Department of Global Health and Department of Sociology, Emory University, 1518 Clifton Rd. NE, Atlanta, GA, 30322, USA, - - 2014
The influences of recent dramatic declines in fertility on girls' and boys' well-being in poorer countries are understudied. In panels of 67-75 poorer countries, using 152-185 Demographic and Health Surveys spanning 1985-2008, we examined how declining total fertility and women's increasing median age at first birth were associated with changes ...
Gribble Kristin E KE Josephine Bay Paul Center for Comparative Molecular Biology and Evolution, Marine Biological Laboratory, Woods Hole, MA, 02543, - - 2014
While many studies have focused on the detrimental effects of advanced maternal age and harmful prenatal environments on progeny, little is known about the role of beneficial non-Mendelian maternal inheritance on aging. Here, we report the effects of maternal age and maternal caloric restriction (CR) on the life span and ...
Longworth Brooke B Curtin University, School of Physiotherapy and Exercise - - 2014
To determine any difference between the prevalence of adolescent idiopathic scoliosis in adolescent, female ballet dancers compared to age-matched non dancers, and establish if any relationships exist between the presence of scoliosis and generalised joint hypermobility, age of menarche, body mass index (BMI) and the number of hours of dance ...
Abu-Amero Khaled K - - 2014
To evaluate total antioxidant status (TAS) in the plasma of primary angle closure glaucoma (PACG) patients and to compare it to that of the control group. Additionally, we aim to investigate the association of various PACG clinical indices with TAS level. Plasma samples were obtained from 139 PACG patients and ...
Hagman Ragnvi R Department of Clinical Sciences, Swedish University of Agricultural Sciences, Uppsala, Sweden. Electronic address: - - 2014
Pyometra is a clinically relevant problem in intact female cats and dogs. The etiology is similar in both animal species, with the disease caused by bacterial infection of a progesterone-sensitized uterus. Here, we studied pyometra in cats with the aim to describe the incidence and probability of developing pyometra based ...
Comfort Kristen K - - 2014
In view of the vast number of new nanomaterials (NMs) that require testing and the constraints associated with animal models, the majority of studies to elucidate nano-toxicological effects have occurred in vitro; with limited correlation and applicability to in vivo systems and realistic, occupational exposure scenarios. In this study, we ...
Groh Ksenia J KJ Eawag, Swiss Federal Institute of Aquatic Science and Technology , Dübendorf , Switzerland - - 2014
Abstract The toxicity of silver nanoparticles (AgNP) to aquatic organisms, including zebrafish (Danio rerio), has been demonstrated, but differing opinions exist on the contribution of the physical properties of the particles themselves and the free dissolved silver ions (Ag(+)) to the observed effects. High concentrations of chloride ions (Cl(-)) in ...
Yin Jiang-An JA Institute of Neuroscience and State Key Laboratory of Neuroscience, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China, and University of Chinese Academy of Sciences, Shanghai 200031, - - 2014
Aging is accompanied with behavioral and cognitive decline. Changes in the neurotransmitter level are associated with the age-related behavioral deterioration, but whether well-known longevity manipulations affect the function of neurotransmitter system in aging animals is largely unclear. Here we report that serotonin (5-HT) and dopamine (DA) level decrease with age ...
Xu Sheng S State Key Laboratory of Forest and Soil Ecology, Institute of Applied Ecology, Chinese Academy of Sciences, Shenyang, 110016, People's Republic of - - 2014
The effects of elevated CO2 (700 ppm) and/or elevated O3 (80 ppb) on different-age needles of Pinus tabulaeformis were studied in open top chambers. Elevated CO2 increased needle dry weight, net photosynthetic rate, and maximum quantum yield of photosystem II in previous and current-year needles. Elevated O3 significantly decreased dry weight, net ...
Obana Akira A Department of Ophthalmology, Seirei Hamamatsu General Hospital, Sumiyoshi 2-12-12, Naka-ku, Hamamatus City, Sizuoka, 430-8558, Japan, - - 2014
Macular pigment is a defense system against phototoxic damage of the retina by visible light. It is still under debate whether or not macular pigment optical density (MPOD) levels decline with age, because the age effect varied depending on the technique used to measure MPOD levels. Resonance Raman spectroscopy (RRS) ...
Nouri Kazem - - 2014
The aim of the present study was to assess if semen quality declines during in vitro fertilization (IVF) and whether or not this phenomenon is triggered by chronic male stress. In order to test this hypothesis, we first investigated a retrospective cohort of 155 male IVF patients (testing cohort). Subsequently, ...
Choi W J WJ Department of Occupational and Environmental Medicine, Gachon University Gil Medical Center, Incheon, Rep. of - - 2014
Concerns have emerged about the adverse effect of phthalates on human health. The aim of this study was to investigate the association between DEHP exposure and atopic dermatitis in Korean children, focusing on the potential dose-response relationship. A matched case-control study was conducted from May to October, 2012. Subjects from ...
Brody Gene H GH Center for Family Research, University of Georgia, 1095 College Station Road, Athens, Georgia, 30602-4527, - - 2014
Telomere length (TL) is an indicator of general systemic aging, with diminished TL associated with several chronic diseases of aging and with heightened mortality risk. Research has begun to focus on the ways in which stress contributes to telomere attrition. The purposes of this study were (a) to establish whether ...
Lepeule Johanna J Exposure, Epidemiology, and Risk Program, Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts, - - 2014
Few studies have been performed on pulmonary effects of air pollution in the elderly, a vulnerable population with low reserve capacity, and mechanisms and susceptibility factors for potential effects are unclear. We evaluated the lag structure of air pollutant associations with lung function and potential effect modification by DNA methylation ...
Nocchi Linda L Department of Biomedical Science, University of Sheffield, Western Bank, Sheffield, S10 2TN, - - 2014
The incidence of bladder conditions such as overactive bladder syndrome and its associated urinary incontinence is highly prevalent in the elderly. However, the mechanisms underlying these disorders are unclear. Studies suggest that the urothelium forms a 'sensory network' with the underlying innervation, alterations in which, could compromise bladder function. As ...
Belloc Stephanie S Eylau/Unilabs Laboratory, Reproductive Biology Unit, 55 Rue Saint Didier, 75016 Paris, France. Electronic address: - - 2014
The recent trend toward delayed parenthood raises major safety concerns because of the adverse effects of aging on couple fertility. Studies have demonstrated that aging clearly affects female fertility, but can also affect male fertility. Although several theories have been proposed, the exact mechanisms responsible for the observed age-related decline ...
Lin Pei-Ying PY Department of Chemistry and Center for Nanoscience and Nanotechnology, National Sun Yat-sen University, Kaohsiung 80424 (Taiwan), Tel: (+886) 75252000 ext. 3931, Fax: - - 2014
We report on the fabrication of a surface-enhanced Raman scattering (SERS) platform, comprised of a three-dimensional (3D) porous eggshell membrane (ESM) scaffold decorated with Ag nanoparticles (NPs). Both native and treated ESM were used, where the treated ESM pore size and fiber crossing density was controlled by timed exposure to ...
Johnson Matthew D - - 2014
Guided by the vulnerability-stress adaptation (VSA) model of marriage and a developmental systems perspective, the current study examined the association of mental health trajectories (depressive symptoms and expressed anger) across the transition to adulthood (ages 18 to 25) with perceived life stress in young adulthood (age 32) and adaptive interaction ...
- - 2014
: The fecundity of women decreases gradually but significantly beginning approximately at age 32 years and decreases more rapidly after age 37 years. Education and enhanced awareness of the effect of age on fertility are essential in counseling the patient who desires pregnancy. Given the anticipated age-related decline in fertility, ...
- - 2014
The fecundity of women decreases gradually but significantly beginning approximately at age 32 years and decreases more rapidly after age 37 years. Education and enhanced awareness of the effect of age on fertility are essential in counseling the patient who desires pregnancy. Given the anticipated age-related decline in fertility, the ...
Kwon Choon Sig CS Department of Economics and Finance, College of Business Adminstration, Kwandong University, Gangneung, - - 2014
There is a lack of information on female urinary incontinence (UI) in South Korea. We investigated the prevalence, risk factors, quality of life (QoL), and healthcare-seeking behaviors of women with UI. We included 9,873 women over the age of 20 years who had participated in the Korea National Health and ...
Onur Simone S Division of Molecular Prevention, Institute of Human Nutrition and Food Science, Christian Albrechts University Kiel, Kiel, - - 2014
Coenzyme Q derivatives (CoQ) are lipid soluble antioxidants that are synthesized endogenously in almost all species and function as an obligatory cofactor of the respiratory chain. There is evidence that CoQ status is altered by age in several species. Here we determined level and redox-state of CoQ in different age ...
Cevik M M Department of Pediatric Surgery, Faculty of Medicine, Harran University, 63100, Sanliurfa, Turkey, - - 2014
Most previous reports have shown that the basic mechanism of inguinal hernia involves insufficient collagen strength and metabolism. The aim of this study was to evaluate whether joint hypermobility is involved in the development of inguinal hernia in children and to investigate oxidative stress parameters and prolidase activity in tissue ...
Jivraj Stephen S Correspondence should be addressed to Stephen Jivraj, Centre for Longitudinal Studies, Institute of Education, University of London, 20 Bedford Way, London WC1H 0AL, UK. E-mail: - - 2014
Objectives.This paper examines age-related changes in subjective well-being (SWB) in later life using multiple measures that cover eudemonic, evaluative, and affective dimensions of well-being.Method.Using data from 5 waves of respondents aged 50 and older from the English Longitudinal Study of Ageing (2002-11), we fit multilevel linear growth curve models to ...
Devos Daniel G H DG Department of Radiology, MRI (-1K12), University Hospital Ghent, De Pintelaan 185, B-9000, Gent, - - 2014
To assess the difference between thoracic and abdominal aortic pulse wave velocity (PWV) in apparently healthy subjects including young adults to elderly subjects. We performed PWV and distensibility measurements and analysis of thoracic and abdominal aortic segments in 96 apparently normal subjects aged 20-80 years with magnetic resonance (MR). Both ...
Bustos Martha L ML University of Pittsburgh, Department of Medicine, Pittsburgh, Pennsylvania, United States ; - - 2014
Rationale: Aging is characterized by functional impairment and reduced capacity to respond appropriately to environmental stimuli and injury. With age, there is an increase in the incidence and severity of chronic and acute lung diseases. However, the relationship between age and the lung's reduced ability to repair is far from ...
Ryan Camilon P P Department of Otolaryngology - Head and Neck Surgery, Medical University of South Carolina, Charleston, SC, USA. Electronic address: - - 2014
Though the effect of age has been studied in some cancer types, its prognostic significance in oropharyngeal squamous cell carcinoma (OPSCC) remains controversial. Our purpose is to determine the impact of age at diagnosis on overall survival (OS) and disease-specific survival (DSS) in patients with OPSCC. If the effect is ...
Halvorsen Sigrun S Department of Cardiology B, Oslo University Hospital, Oslo 0407, - - 2014
The risk of stroke in patients with atrial fibrillation (AF) increases with age. In the ARISTOTLE trial, apixaban when compared with warfarin reduced the rate of stroke, death, and bleeding. We evaluated these outcomes in relation to patient age. A total of 18 201 patients with AF and a raised ...
Franz Carol E CE Department of Psychiatry, University of California, San Diego, La Jolla, CA. Electronic address: - - 2014
Attachment theory has become a key framework for understanding responses to and consequences of trauma across the life course. We predicted that more severe post-traumatic stress (PTS) symptoms at age 37 years would be associated with insecure attachment at age 55 and with worse PTS symptoms 24 years later at ...
Taylor Marcus K MK Biobehavioral Sciences Lab, Warfighter Performance Department, Naval Health Research Center, San Diego, CA, USA; Institute for Interdisciplinary Salivary Bioscience Research, Arizona State University, Tempe, AZ, USA; School of Exercise and Nutritional Sciences, San Diego State University, San Diego, CA, USA. Electronic address: - - 2014
Ample evidence links stress to psychiatric and neurological disease. Although many studies examine stress hormone secretion and receptor activity, exciting new developments signify a shift in focus to neuromodulatory systems influencing neuronal development, survival, and neuroplasticity. The purpose of this study was to characterize salivary nerve growth factor (sNGF) responses ...
Shriram A N AN Regional Medical Research Centre (Indian Council of Medical Research), Post Bag No.13, Port Blair 744 101, Andaman & Nicobar Islands. Electronic address: - - 2014
Mass Drug Administration is being carried out in Andaman and Nicobar Islands, India since 2004. Cross sectional microfilaria (Mf) survey was conducted in Nancowry group of islands, the lone foci of diurnally sub periodic form of bancroftian filariasis in Nicobar district, to examine its eligibility for Transmission Assessment Survey (TAS). ...
Zheng Selin Jinjin J Karolinska Institutet, Institute of Environmental Medicine, Stockholm, Sweden ; - - 2014
Oxidative stress and inflammation may be involved in the etiology of age-related cataract. This study is the first to investigate the association between urinary levels of 8-iso-prostaglandin F<sub>2α</sub> (as a biomarker for systemic oxidative stress in vivo) and 15-keto-dihydro-prostaglandin F<sub>2α</sub> (as a biomarker for systemic inflammation in vivo) and risk ...
Yang Hyo Hyun HH Department of Biochemistry and Molecular Biology, College of Medicine, Yeungnam University, 317-1 Daemyung-Dong, Daegu, 705-717, Republic of - - 2014
Cellular senescence contributes to tissue and organismal aging, tumor suppression and progress, tissue repair and regeneration, and age-related diseases. Thus, aging intervention might be a promising target for treatment and prevention of diverse age-related diseases. In the present study, we investigated whether juglanin purified from the crude extract of Polygonum ...
Rodakowski Juleen J Department of Occupational Therapy, University of Pittsburgh. Electronic address: - - 2014
To examine the additive effect of age on disability for adults with SCI. Prospective cohort study. Setting: Spinal Cord Injury Model Systems. The study sample individuals with SCI with a discharge motor-FIM score and at least one follow-up motor-FIM score who also provided measures of other covariates (N=1,660). Seventy-nine percent ...
Massarsky Andrey A Department of Biology and Centre for Advanced Research in Environmental Genomics, University of Ottawa, Ottawa, Ontario, Canada. Electronic address: - - 2014
The antibacterial properties of silver nanoparticles (AgNPs) are widely exploited in a variety of medical and consumer products. AgNPs in these products can be released into the aquatic environment, however, the potential toxicity of AgNPs to organisms, including fish, is yet to be fully understood. The present study aimed to ...
1 2 3 4 5 6 7 8 9 10 >