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Tohno Yoshiyuki Y Department of Anatomy, Faculty of Medicine, Chiang Mai University, Chiang Mai, 50200, Thailand, - - 2014
To elucidate compositional changes of the ligament with aging, the authors investigated age-related changes of elements in the ligamentum capitis femoris (LCF) of monkeys with a wide range of ages by direct chemical analysis. Used rhesus and Japanese monkeys consisted of 9 males and 22 females, ranging in age from ...
Manning Lydia K LK Department of Gerontology, Concordia University-Chicago, Illinois. - - 2014
In examining the ability of resilience, or the ability to navigate adversity in a manner that protects well-being, to buffer the impact of chronic disease onset on disability in later life, the authors tested 2 hypotheses: (a) People with greater levels of resilience will have lower levels of disability and ...
Murphy Shannon R SR University of - - 2014
Children are uniquely susceptible to ozone because airway and lung growth continues for an extensive period after birth. Early-life exposure of the rhesus monkey to repeated ozone cycles results in region-specific disrupted airway/lung growth but the mediators and mechanisms are poorly understood. Substance P (SP), neurokinin-1 receptor (NK-1R) and nuclear ...
Angeli Suzanne S Buck Institute For Research on Aging, 8001 Redwood Blvd., Novato, CA 94945, USA. glithgow@buckinstitute.org - - 2014
Parkinson's disease (PD) is a debilitating motor and cognitive neurodegenerative disorder for which there is no cure. While aging is the major risk factor for developing PD, clear environmental risks have also been identified. Environmental exposure to the manganese (Mn) metal is a prominent risk factor for developing PD and ...
Smulders S S Center for Environment and Health, KU Leuven, Leuven, - - 2014
Little is known about the impact of engineered nanoparticles (ENPs) on the skin sensitization caused by chemicals. We determined the ability of different ENPs (TiO2 , Ag and SiO2 ) and aged paint particles containing ENPs to modulate the dermal sensitization by a known potent dermal sensitizer. The fur of ...
Oren Noga N Faculty of Medicine, Tel-Aviv University, Tel Aviv, Israel Functional Brain Center, Wohl Institute for Advanced Imaging, Tel-Aviv Sourasky Medical Center, Tel-Aviv, Israel Center for Memory and Attention Disorders, Tel-Aviv Sourasky Medical Center, Tel Aviv, Israel Department of Neurology, Tel-Aviv Sourasky Medical Center, Tel Aviv, - - 2014
The Montreal Cognitive Assessment (MoCA) is a widely used screening test for evaluation of mild cognitive impairment, with a single cutoff for all ages. We examined whether it is associated with age in a sample of cognitively-intact elderly (CIE). The average MoCA score was negatively correlated with age and was ...
Ota Susumu S Department of Rehabilitation and Care, Seijoh University, Aichi, - - 2014
Posture and physical function have been quantified in mature adults, but not in elderly females. To quantify standing posture and measures of physical function in community-dwelling women over the age of 65 years, and to examine relationships between these variables.METHODS: Fifty-three women were recruited from day care service users (average ...
Kitamura H H Department of Work Systems and Health, Institute of Industrial Ecological Science, University of Occupational and Environmental Health, Kitakyushu, Japan - - 2014
This study examines the relationship between toner exposure and its health effects in terms of biomarkers which are known to assess the damages to humans caused by toxic material exposure. The subjects were 1504 male workers aged below 50 in 2003 in a Japanese toner and photocopier manufacturing company. Personal ...
Hayashi Kentaro K Department of Neurosurgery, Nagasaki University School of Medicine, Sakamoto 1-7-1, Nagasaki City, Nagasaki, 852-8501, Japan, - - 2014
Carotid artery stenting (CAS) is a well-accepted treatment for atherosclerotic stenosis of carotid arteries. Since the occurrence of distal embolization with CAS is still a major concern embolus protection devices (EPD) are usually employed during the procedure. We examined two types of embolus protection filters (Angioguard XP (AG); Filterwire EZ ...
Aksu Ugur U Department of Biology, Science Faculty, Zoology Division, Istanbul University, Istanbul, - - 2014
We aimed to test our hypothesis that scavenging reactive oxygen species (ROS) with tempol, a membrane permeable antioxidant, affects the type and magnitude of oxidative damage and stress tolerance through mimetic aging process in Drosophila. Drosophila colonies were randomly divided into three groups: (1) no d-galactose, no tempol; (2) d-galactose ...
Elizur Shai E SE Infertility and IVF Unit, Department of Obstetrics and Gynecology, Chaim Sheba Medical Center , Ramat Gan , Israel , - - 2014
Abstract Introduction: The aim of this study was to evaluate the role of oxidative stress in the process of ovarian aging. Methods: Follicular fluid (FF) from two randomly selected sibling follicles was collected from women undergoing in-vitro fertilization and tested for hydrogen peroxide (H2O2) levels. Results: Group A consists of ...
Mayer Stefanie E SE Department of Psychology, University of Michigan, 530 Church Street, 2261 East Hall, Ann Arbor, MI 48109, USA. Electronic address: - - 2014
Trait and contextual factors can shape individual and group differences in hypothalamic-pituitary-adrenal (HPA) response to stress; but the ways in which these factors may interact with each other to modulate stress activity has rarely been examined. Here, we investigated whether the association between a temperamental self-regulatory trait - Effortful Control ...
Fukushima Yoichi Y Wellness Communications Section, Nestlé Japan Ltd, Tokyo, - - 2014
Reactive oxygen species are known to mediate skin photoaging, which results in the formation of pigmented spots and wrinkles. Coffee is the largest source of polyphenols, which supplies a large number of antioxidants in one's daily life. However, little is known about how much coffee and polyphenol consumption influences skin ...
Kim Dae Hyun DH Molecular Inflammation Research Center for Aging Intervention (MRCA), College of Pharmacy, Pusan National University, Gumjung-gu, Busan, 609-735, Republic of - - 2014
Changes in the activities of FoxOs caused by phosphorylation, acetylation, or ubiquitination induce expressional changes in the genes involved in the modulation of oxidative stress by modifying histones and chromatins and can substantially alter cellular functions during aging and age-related diseases. However, the precise role that FoxO6, a novel member ...
Strand Bjørn Heine BH Institute of Health and Society, University of Oslo, P.O. Box 1130 Blindern, 0318 Oslo, Norway; Norwegian Institute of Public Health, Norway. Electronic address: - - 2014
An inverse relationship between educational level and dementia has been reported in several studies. In this study we investigated the relationship between educational level and dementia related deaths for cohorts of people all born during 1915-39. The cohorts were followed up from adulthood or old age, taking into account possible ...
Drury Stacy S SS Department of Psychiatry (SSD, AS, ZHB, MW, KE), Tulane University School of Medicine, New Orleans, Louisiana; Department of Human Development and Family Studies (EAS, JP), University of Iowa, Ames, Iowa; and Department of Global Community Health Sciences (EM, KPT), Tulane School of Public Health and Tropical Medicine, New Orleans, - - 2014
Given the established relation between testosterone and aging in older adults, we tested whether buccal telomere length (TL), an established cellular biomarker of aging, was associated with testosterone levels in youth. Children, mean age 10.2 years, were recruited from the greater New Orleans area, and salivary testosterone was measured diurnally ...
Rambousková Jolana J Centre for Research of Diabetes, Metabolism and Nutrition, Department of Nutrition, Third Faculty of Medicine, Charles University in Prague, Ruská 87, 100 00 Prague 10, Czech Republic. Electronic address: - - 2014
There is limited research examining the chemical load of toxic metals in the elderly. The aim of the present study was to determine the body burden of lead, cadmium and mercury in association with age, gender, locality, lifestyle factors and potential health impacts among this population and to compare the ...
Bake Björn B Occupational and Environmental Medicine, Sahlgrenska Academy at University of Gothenburg, Sweden; Respiratory Medicine and Allergology, Sahlgrenska Academy at University of Gothenburg, - - 2014
Pollen exposure of allergic subjects with asthma causes increased nitric oxide (NO) in exhaled air (FENO) suggestive of increased airway inflammation. It is, however, unclear to what extent NO production in peripheral airways and alveoli are involved. The aim of the present investigation was to analyze the relationship between central ...
Stessman Jochanan J Jerusalem Institute of Aging Research and Department of Geriatrics and Rehabilitation, Hadassah-Hebrew University Medical Center, Jerusalem, Israel; Hebrew University-Hadassah Medical School, Mount Scopus, Jerusalem, - - 2014
To determine the effect of physical activity (PA) on survival in older adults (70-90) with diabetes mellitus (DM). The Jerusalem Longitudinal Cohort Study (1990-2010) prospectively follows up a representative cohort born in 1920-1921. Home-based assessment. Individuals aged 70 in 1990 (n = 463), 78 in 1998 (n = 972), and 85 in 2005 (n = 1,181). ...
Lizé Anne A Institute of Integrative Biology, University of Liverpool, Liverpool L69 7ZB, UK - - 2014
Mating system variation is profound in animals. In insects, female willingness to remate varies from mating with hundreds of males (extreme polyandry) to never remating (monandry). This variation in female behaviour is predicted to affect the pattern of selection on males, with intense pre-copulatory sexual selection under monandry compared to ...
Yang Hyo Hyun HH Department of Biochemistry and Molecular Biology, College of Medicine, Yeungnam University, 170 Hyunchung-Ro, Daegu, 705-717, Republic of - - 2014
Cellular senescence influences tumor suppression and progress, tissue repair and regeneration, tissue and organismal aging, and age-related diseases. Aging intervention might be an advantageous target for prevention and treatment of diverse age-related diseases. In this study, we investigated whether (-)-loliolide purified from the crude extract of Polygonum aviculare exerted inhibitory ...
Levy Becca R BR Social and Behavioral Sciences Division, Yale School of Public Health, New Haven, Connecticut. - - 2014
To examine whether the age stereotypes of older individuals would become more negative or else show resiliency following stressful events and to examine whether age-stereotype negativity would increase the likelihood of experiencing a stressful event (i.e., hospitalization). Age stereotypes of 231 participants, 70 years and older, were assessed across 10 ...
Chahal Jaswinder J Department of Life Sciences, University of Roehampton, London, - - 2014
The aim of the current study was to investigate the association between loading dose of physical activity, muscle strength and bone density in middle-aged women. Thirty four healthy women (mean age=49.8±7.5years) were recruited. They were requested to wear an accelerometer for a period of 10hours (from 9am to 7pm) on ...
Wu Lili L Department of Pathophysiology, Key Lab for Shock and Microcirculation Research, Southern Medical University, Guangzhou 510515, P. R. - - 2014
Both advanced glycation end products (AGEs) and endoplasmic reticulum (ER) stress play important roles in the development of various diseases. This study aimed to clarify the consequence of AGE-induced ER stress and its underlying mechanisms in human umbilical venous endothelial cells (HUVECs). AGE-induced ER stress was assessed by the increased ...
Mancini A A Department of Medical Sciences, Division of Endocrinology, Catholic University of the Sacred Heart, Rome, Italy. - - 2014
With the purpose of evaluating the role of oxidative stress (OS) in male idiopatic osteoporosis, we have evaluated plasma total antioxidant capacity (TAC) in patients classified according to age (< 65 or ≥ 65 yrs), with normal hormone values and in age-matched healthy control subjects. TAC was evaluated with a ...
Xin L L School of Public Health, Medical College of Soochow University, Suzhou, - - 2014
Due to widely commercial applications of silver nanoparticles (Ag NPs), toxicity assessment of this NP is of great importance. This study aimed to investigate the oxidative stress and heat shock response of Ag NPs at different doses to A549 and HepG2 cells. After treatment with different concentrations of Ag NPs ...
Korkmaz Ceyhan Yonca Y Department of Restorative Dentistry and Prosthodontics, The University of Texas School of Dentistry at Houston, Houston, TX, - - 2014
To evaluate the effect of accelerated aging on color and translucency parameter of composites. Filtek Supreme Ultra Flowable, shades A1, A3, White, Tetric EvoFlow, shades A1, A3, Bleach, and Filtek Z250 shades A1, A3, B1 were evaluated. Color and translucency were recorded using a spectrophotometer after 24-hour storage (baseline) and ...
Surowka A D AD AGH University of Science and Technology, Faculty of Physics and Applied Computer Science, al. A. Mickiewicza 30, 30-059 Krakow, Poland. Electronic address: - - 2014
There is growing evidence that a variety of biochemical processes that underlie the most frequent neurodegenerative diseases may have much in common with those connected with natural aging. It was shown that they involve, among others, lipid peroxidation and/or generation of insoluble in water protein deposits (i.e. alpha-synuclein and/or beta ...
Altundag Aytug A Division of Otorhinolaryngology, Istanbul Surgery Hospital, Ferah Sok. No: 22 Şişli, Istanbul, 34365, Turkey, - - 2014
The aim of the present study was to investigate whether nasal nitric oxide (nNO) levels change in relation to high altitude in a natural setting where the weather conditions were favorable. The present study included 41 healthy volunteers without a history of acute rhinosinusitis within 3 weeks and nasal polyposis. The ...
Tedone Enzo E Geriatric Unit, Department of Medical Sciences and Community Health, University of Milan, Via Pace 9, 20122 Milan, Italy. Electronic address: - - 2014
Centenarians and their offspring are increasingly considered a useful model to study and characterize the mechanisms underlying healthy aging and longevity. The aim of this project is to compare the prevalence of age-related diseases and telomere length (TL), a marker of biological age and mortality, across five groups of subjects: ...
Myint Phyo Kyaw PK School of Medicine & Dentistry, University of Aberdeen, Aberdeen, UK Norwich Research Park Cardiovascular Research Group, Norwich, - - 2014
This study aims to determine whether the prognostic significance of troponins in acute coronary syndrome in predicting mortality varies by age, and if so, to what extent when other prognostic indicators are considered. We analysed Myocardial Ischemia National Audit Project registry data collected between January 2006 and December 2010 and ...
Jung Sora S Center of Experimental and Applied Cutaneous Physiology, Department of Dermatology, Venerology and Allergology, Charité - Universitätsmedizin Berlin, Berlin, - - 2014
Background: The antioxidant status of the human skin provides protection against the destructive action of free radicals. Most antioxidants cannot be synthesized by the human organism itself, but have to be ingested with a healthy nutrition rich in fruit and vegetables. The Korean cuisine is known to be one of ...
Andersen Mousumi M MM Section of Cardiology, Department of Internal - - 2014
Our objective was to determine if increased cardiovascular (CV) stiffness is associated with disability in middle-aged and older adults at risk for congestive heart failure. CV stiffness (brachial pulse pressure/left ventricular stroke volume indexed to body surface area) and total disability (the summed assessment of activities of daily living, mobility, ...
Inglés Marta M Department of Physiotherapy, Faculty of Physiotherapy, University of Valencia, Valencia, - - 2014
To ascertain whether indicators of oxidative damage to lipids (malondialdehyde (MDA)) and proteins (protein carbonylation) are biomarkers of frailty, after adjusting for age, sex, and other possible confounders. Cross-sectional cohort study. Community. Toledo Study for Healthy Aging participants (N = 742, aged 65-95), classified as frail (n = 54), prefrail (n = 278) and nonfrail (n = 410) ...
Luo Pinchao P Center for Studies of Psychological Application, South China Normal University, Guangzhou 510631, PR China; School of Psychology, South China Normal University, Guangzhou 510631, PR - - 2014
Previous studies have extensively reported an advantage of females in empathy as compared with males. It remains to be clarified, however, whether these sex differences are associated with sex specific neural processes underlying empathic response to different intensity of emotional stimulus. The present study examined sex differences in empathy for ...
Park Kyoung Ho KH Department of Otorhinolaryngology, Catholic University of Korea, College of - - 2014
Background: Tinnitus is a common condition and frequently can be annoying to affected individuals. We investigated the prevalence and associated factors for tinnitus in South Korea using the data from the Korea National Health and Nutrition Examination Surveys (KNHANES) during 2009-2011.Methods: KNHANES is a cross-sectional survey of the civilian, non-institutionalized ...
Wu Erin W EW Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, - - 2014
Age-related macular degeneration (AMD) is a complex disease resulting from the interplay of genetic predisposition and environmental exposures, and has been linked to oxidative stress and inflammatory mechanisms. Lead and cadmium can accumulate in human retinal tissues and may damage the retina through oxidative stress, and may thereby play a ...
Marčić Dejan D Department of Applied Entomology, Institute of Pesticides and Environmental Protection, Banatska 31B, P.O. Box 163, 11080, Belgrade, Serbia, - - 2014
Lethal and sublethal effects of the biopesticide Kingbo (oxymatrine 0.2 % + psoralen 0.4 %) on the two-spotted spider mite (Tetranychus urticae Koch) were investigated in laboratory bioassays. The biopesticide was applied to bean leaf discs or primary leaves by using a Potter spray tower. Acute toxicity tests showed no significant ovicidal action: toxic ...
Lamb Yvette N YN School of Psychology, The University of Auckland, New - - 2014
Maternal stress during pregnancy has been associated with a range of adverse outcomes in offspring and the catechol-O-methyltransferase (COMT) gene has been linked to differential susceptibility to the consequences of antenatal stress. This study examined two functional polymorphisms of the COMT gene (rs4680 and rs165599) in relation to maternal perceived ...
Li Mengyun - - 2014
Kinetin (Kn) is a cytokinin growth factor having several anti-aging effects and antioxidant effect reported for cells and organs. To investigate the mechanism underlying the apoptosis events in processing of aging induced by D-gal (D-galactose), we examined the effect of Kn on D-gal-induced aging and apoptosis using nuchal subcutaneous injection. ...
Goessaert An-Sofie AS Department of Urology, Ghent University Hospital, Ghent, - - 2014
This study aims to clarify differences in parameters based on frequency volume chart (FVC) and on daytime and nighttime urine according to the nocturia frequency, age, and gender. This observational study was executed between 2011 and 2013. Participants (>18 years, ≤65 years) with or without nocturia (controls) were included and ...
Martin Sarah B SB Sanders-Brown Center on Aging, University of Kentucky, Lexington, KY, - - 2014
Adults with Down syndrome (DS) develop Alzheimer's disease (AD) neuropathology by 40 years of age. Synaptophysin (SYN) consistently declines with age and is further reduced with sporadic AD. Thus, we hypothesized that SYN would be reduced in DS with AD. The gene for synaptojanin-1 (SYNJ1), involved in synaptic vesicle recycling, ...
Kim Yong-Dae YD Department of Preventive Medicine and Medical Research Institute, College of Medicine, Chungbuk National University, Cheongju, Chungbuk 361-763, Republic of - - 2014
This study aimed to estimate the risks for renal tubular damage and osteoporosis in individuals with long-term environmental Cd exposure. This cross-sectional study comprised 1086 residents living in the vicinity of a copper refinery plant. As the urinary Cd levels increased, the proportion of female subjects with β2-MG ≥300μg/g creatinine ...
Trolle Christian C Department of Endocrinology and Internal Medicine and Medical Research Laboratories, Aarhus University Hospital, Aarhus, - - 2014
Cardiovascular disease is a cardinal trait of Turner syndrome (TS), causing half of the 3-fold excess mortality. Since osteoprotegerin (OPG) is as a potential biomarker of cardiovascular disease, this cross-sectional and prospective study aimed at elucidating OPG levels in TS and its relationship to aortic diameter as well as validated ...
La Ju A - - 2014
We report a method for controlling the detection sensitivity to or the degree of etching of Ag nanocubes by radicals by modifying their surfaces with poly(acrylic acid) or poly(allylamine hydrochloride) for wide-range quantification of radical compounds. The degree of Ag nanocube etching is influenced by the concentrations of the polyelectrolytes ...
Li Hao H Key Laboratory of Pesticide & Chemical Biology of Ministry of Education, Institute of Environmental Chemistry, College of Chemistry, Central China Normal University, Wuhan 430079, P. R. China. - - 2014
We demonstrate that the high oxygen density characteristic of BiOCl {001} facets ensures the fast generation of oxygen vacancies in ethylene glycol under microwave irradiation, resulting in in situ nucleation and growth of Ag on the {001} facets of BiOCl single-crystalline nanosheets. The resulting Ag selectively deposited BiOCl single-crystalline nanosheets ...
Collinson Simon Lowes SL Department of Psychological Medicine, National University of Singapore, Singapore Gerontological Research Programme, Faculty of Medicine, National University of Singapore, Singapore Department of Psychology, National University of Singapore, Singapore - - 2014
Asia will experience a surge in dementia prevalence within the next 20-40 years, but there is a dearth of well-normed neuropsychological tests that could assist with dementia diagnosis. Here, we report normative data for the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS) in Elderly ethnic Chinese Singaporeans aged ...
Reissland Nadja N a Department of Psychology , Durham University , Durham , - - 2014
This longitudinal observational study investigated whether foetuses change their hand preference with gestational age, and also examined the effects of maternal stress on lateralized foetal self-touch. Following ethical approval, fifteen healthy foetuses (eight girls and seven boys) were scanned four times from 24 to 36 weeks gestation. Self-touch behaviours which ...
Johansson Klara K Division of Family Medicine, Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden - - 2014
Physical activity is an important public health issue. Factors shown to be associated with physical activity are parenthood and country-level gender equality, while the importance of individual gender equality (in parenthood or in general) remains to explore. In Scandinavia, where parental leave can be shared equally between mothers and fathers, ...
Epel Elissa S ES Department of Psychiatry, University of California, San Francisco. - - 2014
The rate of biological aging is modulated in part by genes interacting with stressor exposures. Basic research has shown that exposure to short-term stress can strengthen cellular responses to stress ("hormetic stress"). Hormetic stress promotes longevity in part through enhanced activity of molecular chaperones and other defense mechanisms. In contrast, ...
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