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Arnardottir Hildur H HH Center for Experimental Therapeutics and Reperfusion Injury, Department of Anesthesiology, Perioperative and Pain Medicine, Harvard Institutes of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA - - 2014
Aging is associated with an overt inflammatory phenotype and physiological decline. Specialized proresolving lipid mediators (SPMs) are endogenous autacoids that actively promote resolution of inflammation. In this study, we investigated resolution of acute inflammation in aging and the roles of SPMs. Using a self-resolving peritonitis and resolution indices coupled with ...
Waalewijn-Kool Pauline L PL Department of Ecological Science, Faculty of Earth and Life Sciences, VU University, De Boelelaan 1085, 1081 HV, Amsterdam, The - - 2014
The growing use of silver nanoparticles (Ag-NP) triggered an increasing interest in their environmental fate and possible ecotoxicological impacts. To investigate the potential risk of Ag-NP to soil organisms, the springtail Folsomia candida was exposed to Ag-NP (reported diameter size 3-8 nm) and AgNO3 in Lufa 2.2 natural soil for 28 days ...
Moresco Maurício Bianchini MB Laboratory of Oxidative Stress and Atmospheric Pollution, Federal University of Health Sciences of Porto Alegre (UFCSPA), Av. Sarmento Leite, 245, Centro, 90050-170, Porto Alegre, RS, Brazil, - - 2014
Asthma is a multifactorial disease and its severity varies with the inflammatory status of the patient. It has been hypothesized that deficiency of trace elements has an important role in the etiology of asthma. The aim of the study was to evaluate the concentration of trace elements in nails of ...
Dorsch R R Roswitha Dorsch, Medizinische Kleintierklinik, der Ludwig-Maximilians-Universität München, Veterinärstraße 13, 80539 München, Email: - - 2014
To investigate epidemiologic data, clinical signs, results of urinalysis and causes of lower urinary tract disease in a German veterinary hospital population of cats and to determine if the demographic data, history, clinical signs and urinalysis results correlate with a particular etiology. Cats presented with signs of feline lower urinary ...
Claes A A Gluck Equine Research Center, Department of Veterinary Science, University of Kentucky, Lexington, KY 40546-0099, - - 2014
Anti-Müllerian hormone (AMH) is a granulosa-cell derived glycoprotein which plays an important inhibitory role during folliculogenesis. Concentrations of AMH are highly correlated with antral follicle counts (AFC) in other species which in turn is related to follicular reserve. Relatively little is known about AMH and AFC in the mare. To ...
He Weiwei - - 2014
An effective way for promoting photocatalytic activity of a semiconductor is deposition of noble metal nanoparticles (NPs) onto it. In this paper, we deposited Ag and Pd onto ZnO NPs to form ZnO/Ag and ZnO/Pd hybrid nanostructures. It was found that both Ag and Pd nanocomponents can greatly enhance the ...
Sindi Shireen S Centre for Studies on Human Stress, Mental Health Research Centre Fernand Seguin, Hospital Louis H Lafontaine, Montreal, Quebec, Canada; Department of Neurology and Neurosurgery, McGill University, Montreal, Quebec, - - 2014
The hypothalamic pituitary adrenal axis production of the stress hormone cortisol interacts with the hippocampal formation and impacts memory function. A growing interest is to determine whether hippocampal volume (HV) predicts basal and/or reactive cortisol levels in young and older adults. Recent evidence shows that contextual features in testing environments ...
Fabbri Elisa E Intramural Research Program, National Institute on Aging, National Institutes of Health, Baltimore, Maryland. Department of Medical and Surgical Sciences, University of Bologna, Italy. - - 2014
Multimorbidity increases with aging, but risk factors beyond age are unknown. To investigate the association of inflammatory and anabolic hormonal biomarkers with presence and prospective development of multimorbidity. Nine-year longitudinal study of 1018 participants aged 60 years or older (InCHIANTI Study). Multimorbidity was evaluated at baseline and follow-up visits as ...
Stephan Yannick Y University of Montpellier, France. Electronic address: - - 2014
Subjective age, or how young or old individuals experience themselves to be, is related to a range of health-related outcomes in old age, including mortality risk. Little is known, however, about its association with markers of systemic inflammation. Using data from the Health and Retirement Study (HRS), the present study ...
Ewa Grzebyk - - 2014
Advanced glycation endproducts (AGE) and advanced oxidation protein products (AOPP) play a pivotal role in the development of diabetes associated diseases. The herbal medicines Padma 28 and Padma Circosan have shown effectiveness in symptoms of diabetes associated diseases and have antioxidant effects. It is not known whether inhibition of AGE ...
Webb Ian G IG Wellington Cardiovascular Research Group, Wellington, New Zealand; Department of Cardiology, Wellington Hospital, Wellington, New - - 2014
This study aimed to determine the frequency of baseline high-sensitivity troponin T (hs-TnT) elevation in different age groups presenting to the Emergency Department without acute coronary syndromes (ACS) or other acute illnesses known to cause to troponin elevation. We additionally sought to determine whether the relationship between age and hs-TnT ...
Valgimigli Luca L Department of Chemistry "G. Ciamician", University of Bologna, 40126, Bologna, - - 2014
The oxidative stress theory of aging has brought to the implicit expectation that oxidative stress increases with aging. Unfortunately, a broad investigation in humans is missing due to limitations of conventional oxidative stress status (OSS) analyses. Here we show that the OSS measured in peripheral blood of 247 healthy volunteers, ...
Braun Joseph M JM Department of Epidemiology, Brown University School of Public Health, Brown University, Providence, Rhode Island, - - 2014
Early life bisphenol A (BPA) exposure may increase childhood obesity risk, but few prospective epidemiological studies have investigated this relationship. To determine if early life BPA exposure was associated with increased body mass index (BMI) at 2-5 years of age in 297 mother-child pairs from Cincinnati, OH (HOME Study). Urinary ...
Schöttker Ben B Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Heidelberg, Germany. - - 2014
The free radical/oxidative stress theory of aging has recently received much attention but the association of oxidative stress markers with all-cause mortality was not yet assessed in humans. We measured derivatives of reactive oxygen metabolites (d-ROM) as a proxy for the reactive oxygen species concentration and total thiol levels (TTL) ...
Christensen Jannie Marie JM Department of Culture and Society, Section for Medieval and Renaissance Archaeology, Aarhus University, Moesgård Allé 20, DK-8270, Højbjerg, - - 2014
During 13 winter weeks an experimental archaeology project was undertaken in two Danish reconstructed Viking Age houses with indoor open fireplaces. Volunteers inhabited the houses under living conditions similar to those of the Viking Age, including cooking and heating by wood-fire. Carbon monoxide (CO) and particulate matter (PM2.5 ) were ...
Tohno Yoshiyuki Y Department of Anatomy, Faculty of Medicine, Chiang Mai University, Chiang Mai, 50200, Thailand, - - 2014
To elucidate compositional changes of the ligament with aging, the authors investigated age-related changes of elements in the ligamentum capitis femoris (LCF) of monkeys with a wide range of ages by direct chemical analysis. Used rhesus and Japanese monkeys consisted of 9 males and 22 females, ranging in age from ...
Manning Lydia K LK Department of Gerontology, Concordia University-Chicago, Illinois. - - 2014
In examining the ability of resilience, or the ability to navigate adversity in a manner that protects well-being, to buffer the impact of chronic disease onset on disability in later life, the authors tested 2 hypotheses: (a) People with greater levels of resilience will have lower levels of disability and ...
Murphy Shannon R SR University of - - 2014
Children are uniquely susceptible to ozone because airway and lung growth continues for an extensive period after birth. Early-life exposure of the rhesus monkey to repeated ozone cycles results in region-specific disrupted airway/lung growth but the mediators and mechanisms are poorly understood. Substance P (SP), neurokinin-1 receptor (NK-1R) and nuclear ...
Angeli Suzanne S Buck Institute For Research on Aging, 8001 Redwood Blvd., Novato, CA 94945, USA. glithgow@buckinstitute.org - - 2014
Parkinson's disease (PD) is a debilitating motor and cognitive neurodegenerative disorder for which there is no cure. While aging is the major risk factor for developing PD, clear environmental risks have also been identified. Environmental exposure to the manganese (Mn) metal is a prominent risk factor for developing PD and ...
Smulders S S Center for Environment and Health, KU Leuven, Leuven, - - 2014
Little is known about the impact of engineered nanoparticles (ENPs) on the skin sensitization caused by chemicals. We determined the ability of different ENPs (TiO2 , Ag and SiO2 ) and aged paint particles containing ENPs to modulate the dermal sensitization by a known potent dermal sensitizer. The fur of ...
Oren Noga N Faculty of Medicine, Tel-Aviv University, Tel Aviv, Israel Functional Brain Center, Wohl Institute for Advanced Imaging, Tel-Aviv Sourasky Medical Center, Tel-Aviv, Israel Center for Memory and Attention Disorders, Tel-Aviv Sourasky Medical Center, Tel Aviv, Israel Department of Neurology, Tel-Aviv Sourasky Medical Center, Tel Aviv, - - 2014
The Montreal Cognitive Assessment (MoCA) is a widely used screening test for evaluation of mild cognitive impairment, with a single cutoff for all ages. We examined whether it is associated with age in a sample of cognitively-intact elderly (CIE). The average MoCA score was negatively correlated with age and was ...
Ota Susumu S Department of Rehabilitation and Care, Seijoh University, Aichi, - - 2014
Posture and physical function have been quantified in mature adults, but not in elderly females. To quantify standing posture and measures of physical function in community-dwelling women over the age of 65 years, and to examine relationships between these variables.METHODS: Fifty-three women were recruited from day care service users (average ...
Kitamura H H Department of Work Systems and Health, Institute of Industrial Ecological Science, University of Occupational and Environmental Health, Kitakyushu, Japan - - 2014
This study examines the relationship between toner exposure and its health effects in terms of biomarkers which are known to assess the damages to humans caused by toxic material exposure. The subjects were 1504 male workers aged below 50 in 2003 in a Japanese toner and photocopier manufacturing company. Personal ...
Boks Marco P MP Brain Center Rudolf Magnus, Department of Psychiatry, University Medical Center Utrecht, The Netherlands. Electronic address: - - 2014
Several studies have reported an association between traumatic stress and telomere length suggesting that traumatic stress has an impact on ageing at the cellular level. A newly derived tool provides an additional means to investigate cellular ageing by estimating epigenetic age based on DNA methylation profiles. We therefore hypothesise that ...
Banach Maciej M Department of Hypertension, Chair of Nephrology and Hypertension, Medical University of Lodz, Poland. Electronic address: - - 2014
The aim of the study was to identify the association of systolic blood pressure (SBP) levels with cardiovascular events, all-cause mortality, and falls among elderly persons taking antihypertensive medication. US adults ≥45years of age taking antihypertensive medication enrolled in the REGARDS study were categorized into 3 age groups: 55-64, 65-74 ...
Hayashi Kentaro K Department of Neurosurgery, Nagasaki University School of Medicine, Sakamoto 1-7-1, Nagasaki City, Nagasaki, 852-8501, Japan, - - 2014
Carotid artery stenting (CAS) is a well-accepted treatment for atherosclerotic stenosis of carotid arteries. Since the occurrence of distal embolization with CAS is still a major concern embolus protection devices (EPD) are usually employed during the procedure. We examined two types of embolus protection filters (Angioguard XP (AG); Filterwire EZ ...
Aksu Ugur U Department of Biology, Science Faculty, Zoology Division, Istanbul University, Istanbul, - - 2014
We aimed to test our hypothesis that scavenging reactive oxygen species (ROS) with tempol, a membrane permeable antioxidant, affects the type and magnitude of oxidative damage and stress tolerance through mimetic aging process in Drosophila. Drosophila colonies were randomly divided into three groups: (1) no d-galactose, no tempol; (2) d-galactose ...
Gomes Tânia T CIMA, Faculty of Science and Technology, University of Algarve, Campus de Gambelas, 8005-139 Faro, Portugal. Electronic address: - - 2014
Silver nanoparticles (Ag NPs) have emerged as one of the most commonly used NPs in a wide range of industrial and commercial applications. This has caused increasing concern about their fate in the environment as well as uptake and potential toxicity towards aquatic organisms. Accordingly, mussels Mytilus galloprovincialis were exposed ...
Elizur Shai E SE Infertility and IVF Unit, Department of Obstetrics and Gynecology, Chaim Sheba Medical Center , Ramat Gan , Israel , - - 2014
Abstract Introduction: The aim of this study was to evaluate the role of oxidative stress in the process of ovarian aging. Methods: Follicular fluid (FF) from two randomly selected sibling follicles was collected from women undergoing in-vitro fertilization and tested for hydrogen peroxide (H2O2) levels. Results: Group A consists of ...
Mayer Stefanie E SE Department of Psychology, University of Michigan, 530 Church Street, 2261 East Hall, Ann Arbor, MI 48109, USA. Electronic address: - - 2014
Trait and contextual factors can shape individual and group differences in hypothalamic-pituitary-adrenal (HPA) response to stress; but the ways in which these factors may interact with each other to modulate stress activity has rarely been examined. Here, we investigated whether the association between a temperamental self-regulatory trait - Effortful Control ...
Fukushima Yoichi Y Wellness Communications Section, Nestlé Japan Ltd, Tokyo, - - 2014
Reactive oxygen species are known to mediate skin photoaging, which results in the formation of pigmented spots and wrinkles. Coffee is the largest source of polyphenols, which supplies a large number of antioxidants in one's daily life. However, little is known about how much coffee and polyphenol consumption influences skin ...
Kim Dae Hyun DH Molecular Inflammation Research Center for Aging Intervention (MRCA), College of Pharmacy, Pusan National University, Gumjung-gu, Busan, 609-735, Republic of - - 2014
Changes in the activities of FoxOs caused by phosphorylation, acetylation, or ubiquitination induce expressional changes in the genes involved in the modulation of oxidative stress by modifying histones and chromatins and can substantially alter cellular functions during aging and age-related diseases. However, the precise role that FoxO6, a novel member ...
Strand Bjørn Heine BH Institute of Health and Society, University of Oslo, P.O. Box 1130 Blindern, 0318 Oslo, Norway; Norwegian Institute of Public Health, Norway. Electronic address: - - 2014
An inverse relationship between educational level and dementia has been reported in several studies. In this study we investigated the relationship between educational level and dementia related deaths for cohorts of people all born during 1915-39. The cohorts were followed up from adulthood or old age, taking into account possible ...
Hou Gang G Department of Orthopedics, Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, - - 2014
Aging is a major factor associated with lumber intervertebral disc degeneration, and oxidative stress is known to play an essential role in the pathogenesis of many age-related diseases. In this study, we investigated oxidative stress in intervertebral discs of Wistar rats in three different age groups: youth, adult, and geriatric. ...
Drury Stacy S SS Department of Psychiatry (SSD, AS, ZHB, MW, KE), Tulane University School of Medicine, New Orleans, Louisiana; Department of Human Development and Family Studies (EAS, JP), University of Iowa, Ames, Iowa; and Department of Global Community Health Sciences (EM, KPT), Tulane School of Public Health and Tropical Medicine, New Orleans, - - 2014
Given the established relation between testosterone and aging in older adults, we tested whether buccal telomere length (TL), an established cellular biomarker of aging, was associated with testosterone levels in youth. Children, mean age 10.2 years, were recruited from the greater New Orleans area, and salivary testosterone was measured diurnally ...
Rambousková Jolana J Centre for Research of Diabetes, Metabolism and Nutrition, Department of Nutrition, Third Faculty of Medicine, Charles University in Prague, Ruská 87, 100 00 Prague 10, Czech Republic. Electronic address: - - 2014
There is limited research examining the chemical load of toxic metals in the elderly. The aim of the present study was to determine the body burden of lead, cadmium and mercury in association with age, gender, locality, lifestyle factors and potential health impacts among this population and to compare the ...
Bake Björn B Occupational and Environmental Medicine, Sahlgrenska Academy at University of Gothenburg, Sweden; Respiratory Medicine and Allergology, Sahlgrenska Academy at University of Gothenburg, - - 2014
Pollen exposure of allergic subjects with asthma causes increased nitric oxide (NO) in exhaled air (FENO) suggestive of increased airway inflammation. It is, however, unclear to what extent NO production in peripheral airways and alveoli are involved. The aim of the present investigation was to analyze the relationship between central ...
Stessman Jochanan J Jerusalem Institute of Aging Research and Department of Geriatrics and Rehabilitation, Hadassah-Hebrew University Medical Center, Jerusalem, Israel; Hebrew University-Hadassah Medical School, Mount Scopus, Jerusalem, - - 2014
To determine the effect of physical activity (PA) on survival in older adults (70-90) with diabetes mellitus (DM). The Jerusalem Longitudinal Cohort Study (1990-2010) prospectively follows up a representative cohort born in 1920-1921. Home-based assessment. Individuals aged 70 in 1990 (n = 463), 78 in 1998 (n = 972), and 85 in 2005 (n = 1,181). ...
Lizé Anne A Institute of Integrative Biology, University of Liverpool, Liverpool L69 7ZB, UK - - 2014
Mating system variation is profound in animals. In insects, female willingness to remate varies from mating with hundreds of males (extreme polyandry) to never remating (monandry). This variation in female behaviour is predicted to affect the pattern of selection on males, with intense pre-copulatory sexual selection under monandry compared to ...
Yang Hyo Hyun HH Department of Biochemistry and Molecular Biology, College of Medicine, Yeungnam University, 170 Hyunchung-Ro, Daegu, 705-717, Republic of - - 2014
Cellular senescence influences tumor suppression and progress, tissue repair and regeneration, tissue and organismal aging, and age-related diseases. Aging intervention might be an advantageous target for prevention and treatment of diverse age-related diseases. In this study, we investigated whether (-)-loliolide purified from the crude extract of Polygonum aviculare exerted inhibitory ...
Levy Becca R BR Social and Behavioral Sciences Division, Yale School of Public Health, New Haven, Connecticut. - - 2014
To examine whether the age stereotypes of older individuals would become more negative or else show resiliency following stressful events and to examine whether age-stereotype negativity would increase the likelihood of experiencing a stressful event (i.e., hospitalization). Age stereotypes of 231 participants, 70 years and older, were assessed across 10 ...
Chahal Jaswinder J Department of Life Sciences, University of Roehampton, London, - - 2014
The aim of the current study was to investigate the association between loading dose of physical activity, muscle strength and bone density in middle-aged women. Thirty four healthy women (mean age=49.8±7.5years) were recruited. They were requested to wear an accelerometer for a period of 10hours (from 9am to 7pm) on ...
Wu Lili L Department of Pathophysiology, Key Lab for Shock and Microcirculation Research, Southern Medical University, Guangzhou 510515, P. R. - - 2014
Both advanced glycation end products (AGEs) and endoplasmic reticulum (ER) stress play important roles in the development of various diseases. This study aimed to clarify the consequence of AGE-induced ER stress and its underlying mechanisms in human umbilical venous endothelial cells (HUVECs). AGE-induced ER stress was assessed by the increased ...
Mancini A A Department of Medical Sciences, Division of Endocrinology, Catholic University of the Sacred Heart, Rome, Italy. - - 2014
With the purpose of evaluating the role of oxidative stress (OS) in male idiopatic osteoporosis, we have evaluated plasma total antioxidant capacity (TAC) in patients classified according to age (< 65 or ≥ 65 yrs), with normal hormone values and in age-matched healthy control subjects. TAC was evaluated with a ...
Xin L L School of Public Health, Medical College of Soochow University, Suzhou, - - 2014
Due to widely commercial applications of silver nanoparticles (Ag NPs), toxicity assessment of this NP is of great importance. This study aimed to investigate the oxidative stress and heat shock response of Ag NPs at different doses to A549 and HepG2 cells. After treatment with different concentrations of Ag NPs ...
Korkmaz Ceyhan Yonca Y Department of Restorative Dentistry and Prosthodontics, The University of Texas School of Dentistry at Houston, Houston, TX, - - 2014
To evaluate the effect of accelerated aging on color and translucency parameter of composites. Filtek Supreme Ultra Flowable, shades A1, A3, White, Tetric EvoFlow, shades A1, A3, Bleach, and Filtek Z250 shades A1, A3, B1 were evaluated. Color and translucency were recorded using a spectrophotometer after 24-hour storage (baseline) and ...
Surowka A D AD AGH University of Science and Technology, Faculty of Physics and Applied Computer Science, al. A. Mickiewicza 30, 30-059 Krakow, Poland. Electronic address: - - 2014
There is growing evidence that a variety of biochemical processes that underlie the most frequent neurodegenerative diseases may have much in common with those connected with natural aging. It was shown that they involve, among others, lipid peroxidation and/or generation of insoluble in water protein deposits (i.e. alpha-synuclein and/or beta ...
Altundag Aytug A Division of Otorhinolaryngology, Istanbul Surgery Hospital, Ferah Sok. No: 22 Şişli, Istanbul, 34365, Turkey, - - 2014
The aim of the present study was to investigate whether nasal nitric oxide (nNO) levels change in relation to high altitude in a natural setting where the weather conditions were favorable. The present study included 41 healthy volunteers without a history of acute rhinosinusitis within 3 weeks and nasal polyposis. The ...
Tedone Enzo E Geriatric Unit, Department of Medical Sciences and Community Health, University of Milan, Via Pace 9, 20122 Milan, Italy. Electronic address: - - 2014
Centenarians and their offspring are increasingly considered a useful model to study and characterize the mechanisms underlying healthy aging and longevity. The aim of this project is to compare the prevalence of age-related diseases and telomere length (TL), a marker of biological age and mortality, across five groups of subjects: ...
Prunas Antonio A Department of Psychology, University of Milan-Bicocca, Piazza dell'Ateneo Nuovo, 1, 20126, Milan, Italy. Electronic address: - - 2014
The aim of the present study is to explore the association between defensive functioning (as assessed through the REM-71) and psychiatric symptoms in a large sample from the community, and the moderating role of age and gender on that association. Furthermore, we explored the concurrent validity of REM-71 as compared ...
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