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Results 251 - 300 of 945
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Ermantas Nilay - - 2010
Hypothyroidism causes a tendency for cardiovascular diseases. It was recently shown that thrombin-activatable fibrinolysis inhibitor (TAFI) attenuates fibrinolysis and also fibrin-plasminogen interaction by the removal of lysine and arginine residues from fibrin monomers. The aim of this study was to determine the effects of overt hypothyroidism on the levels of ...
Rai B - - 2009
Age estimation is not only important for clinical but also for medico-legal purposes. The present study is an attempt to estimate the chronologic age based on the stages of third molar development following the eight stages (A-H) method of Demirjian et al8 and to compare third molar development by sex ...
Soldin Steven J - - 2010
We evaluated the clinical validity of serum FT4 measurements by assessing its correlation with log TSH. To provide pediatric reference intervals (representative ranges) for FT4, and TSH on the Architect ci8200 integrated system. This population-based study encompassed 6023 children (3369 females and 2654 males). The percentile and Hoffmann approaches for ...
Simonsick Eleanor M - - 2009
Health risks associated with subclinical hypothyroidism in older adults are unclear. Our objective was to compare the functional mobility of people aged 70 to 79 years by thyroid function categorized by thyrotropin (TSH) level as euthyroid (>or=0.4 to <4.5 mIU/L), mild subclinical hypothyroid (>or=4.5 to <7.0 mIU/L), or moderate subclinical ...
Terzidis K - - 2010
OBJECTIVES: Thyroid autoimmunity decreases in the very old. We investigated whether glucocorticoid (GC) activity, which increases in old age, is involved in this process. SUBJECTS AND METHODS: A total of 321 ambulatory subjects (age 51-95 years, median 71, 207 female) were studied. Thyroid function tests, cortisol, glucose, insulin and biochemical ...
Madeira Luciana Gonçalves - - 2010
Mechanisms accounting for sex-related differences in the sweat response remain to be elucidated. In the present study, we focused on differences in sweat gland cholinergic sensitivity between males and females. Since, males usually possess higher aerobic capacity than females, we investigated sweating in males and females grouped according to aerobic ...
Huang Chia-Chang - - 2010
Hypothyroidism is a common disorder in older people, and may be asymptomatic and hard to be diagnosed. The main purpose of this study was to evaluate the distribution of serum thyrotropin (thyroxin-stimulating hormone, TSH) among asymptomatic older people in Taiwan, and to evaluate the relationship between age and serum TSH. ...
Schell Lawrence M LM University at Albany, Department of Anthropology, Albany, NY 12222, USA. - - 2010
Endocrine disruption has become a significant human health concern, but is difficult to study outside of the laboratory for several reasons including the multiplicity of exposures, the difficulty in assessing each exposure, and the variety of possible outcomes among human populations. This review summarizes our studies of the relationships of ...
Wilsher S - - 2009
Fillies completely devoid of endometrial glands (uterine gland knockout; UGKO) would make ideal experimental models in which to study the role of endometrial histotroph in embryogenesis and early fetal development in the mare. Administration of a synthetic progestagen plus oestrogen to newborn filly foals and, thereafter, at regular intervals to ...
Pereira C P M - - 2009
The present study analyzed the effects of the chemical compound fipronil, active ingredient of Frontline (acaricide and insecticide), on the salivary glands of unfed and semi-engorged female Rhipicephalus sanguineus tick. Unfed females were only exposed to the concentration of 1 ppm of fipronil, while semi-engorged females were treated with fipronil ...
Guth S - - 2009
BACKGROUND: The prevalence of thyroid nodules in a healthy population is high: in the German Papillon study, nationwide ultrasound screening of more than 90 000 people using 7.5 MHz scanners revealed the presence of thyroid nodules in 33% of the normal population. A study employing more sensitive 13 MHz scanners ...
McCann Louise C - - 2009
PURPOSE: To determine the differential features of tear physiology and meibomian gland function in blepharitics for ascertaining the diagnostic potential of a number of clinical tests. METHODS: Two groups of subjects, 15 with clinically diagnosed blepharitis (11 women and 5 men mol/L; age 60.9 +/- 12.5; range 41-79) and 15 ...
Valeix Pierre - - 2009
OBJECTIVE: To assess dietary iodine intakes among adults and to investigate the relationships of dietary, lifestyle, demographic and geographical characteristics with dietary iodine status. Adequacy of iodine intakes was also assessed. DESIGN: Cross-sectional study. Linear regression analyses and logistic regression modelling were used to determine correlates of iodine intakes. Usual ...
Gatseva P D - - 2009
OBJECTIVES: To assess the effectiveness of iodine prophylaxis in schoolchildren, living in a rural area in South Bulgaria, after the introduction of salt iodization. STUDY DESIGN: The study subjects were 114 schoolchildren (59 boys and 55 girls), aged 11-14 years, living in a rural area in Bulgaria. Urinary iodine concentration ...
Tenpenny K Elliott - - 2009
OBJECTIVE: To investigate reports of iodine-deficiency disorder in a specific area of Haiti. METHODS: In March 2008, this cross-sectional study was performed in an area 15 miles northeast of Jacmel, Haiti, within the Cha?ne de la Selle Mountains. Before arrival of the study team, an announcement was made throughout local ...
Kilfoy Briseis A - - 2009
Thyroid cancer incidence rates have increased worldwide for decades, although more for papillary carcinomas than other types and more for females than males. There are few known thyroid cancer risk factors except female gender, and the reasons for the increasing incidence and gender differences are unknown. We used the National ...
Haymart Megan R - - 2009
Unique among malignancies, age is a key prognostic indicator for well-differentiated thyroid cancer. Patients aged <45 years can have the same degree of disease involvement and a distinctly different prognosis than those aged >45. Although the reason for the association between age and outcome is not entirely clear, it does ...
Severinski Srećko - - 2009
The aim of the study was to evaluate the natural course and potential risk factors of autoimmune thyroiditis (AIT) and thyroid dysfunction, and their influences on growth and glycemic control in children and adolescents with type 1 diabetes mellitus (T1D). The study comprised 148 subjects (age range 1-21 years; males ...
Bayram F - - 2009
BACKGROUND: The prevalence of goitre and urinary iodine excretion (UIE) indicate endemic iodine deficiency (ID) in a population. Previous studies have shown that Kayseri is one of the most iodine-deficient areas in Turkey. The aim of this study was to determine the prevalence of goitre, evaluate the degree of ID, ...
Usha Menon V - - 2009
India is in the transition phase from iodine deficiency to iodine sufficiency, and this is expected to change the thyroid status of the population. The thyroid status and auto-immune status of adult Indian population in the postiodisation phase is largelyunknown, and this study was conducted to answer this question. A ...
Magnanti Brooke L - - 2009
A previous study found a thyroid cancer excess in Cumbria following the Chernobyl explosion, but did not analyse sex-specific effects. This study examines sex differences in the incidence of thyroid cancer. Ninety-five primary thyroid carcinomas (69 females, 26 males) diagnosed in those aged 0-24 during 1968-2005 were identified from the ...
Atzmon Gil - - 2009
The distribution of serum TSH shifts progressively to higher concentrations with age. The aim of the study was to determine whether the population shift in TSH distribution to higher concentrations with aging extends to people of exceptional longevity, namely centenarians, and to assess the relationship between concentrations of TSH and ...
Estaquio Carla - - 2009
BACKGROUND: The goal of this study was to provide reference ranges for thyrotropin (TSH) and free thyroxine (fT(4)) based on data collected from a disease-free sample of French middle-aged adults. METHODS: A total of 3218 subjects participating in the Suppl??mentation en Vitamines et Min??raux Antioxydants (SU.VI.MAX) study had measurements for ...
Bhansali Anil - - 2009
Precocious puberty in a child less than 3 years of age is usually gonadotropin dependent and is often associated with extrasellar central nervous system disorders. The present report describes the case of a 2½-year-old girl who presented with gonadotropin-independent precocious puberty and had a sellar mass. She was referred for ...
Nemolato Sonia - - 2009
Thymosin beta(4), its sulfoxide, and thymosin beta(10) were detected in whole saliva of human pre-term newborns by reversed-phase high performance chromatography coupled to electrospray ion-trap mass spectrometry. Despite high inter-individual variability, concentration of beta-thymosins increases with an inversely proportional trend to postmenstrual age (PMA: gestational age plus chronological age after ...
Nishimaki Momoko - - 2009
Painless thyroiditis is characterized by transient thyrotoxicosis with complete recovery. Some patients, however, have repeated episodes of thyrotoxicosis, for which the mechanism of recurrence is not clear. We therefore studied the clinical characteristics in 8 patients with 4 or more episodes of thyrotoxicosis and 40 control patients. The age at ...
Gautron Laurent - - 2009
The pituitary gland undergoes important changes in cellular plasticity throughout life, consequently leading to hormonal output changes. The intermediate filament nestin plays a crucial role in cells that retain plasticity during development, aging and tumorigenesis. Here, we describe robust nestin immunoreactivity in glial-like cells of the intermediate lobe and in ...
Paz-Filho Gilberto - - 2009
: Thyroid function is closely related to leptin's secretion by the adipose tissue. In states of leptin-deficiency, the circadian rhythm of TSH is altered, leading to central hypothyroidism in animal models. In humans, central hypothyroidism has also been described in rare cases of congenital leptin deficiency. However, the thyroid phenotype ...
Vejbjerg Pernille - - 2009
OBJECTIVE: Marked differences in pattern of thyroid dysfunction are seen in populations with different iodine intakes. We evaluated the influence of a higher iodine intake on thyroid hormone levels and the prevalence of thyroid dysfunction in the Danish population. DESIGN: Two cross-sectional studies matched on a group level according to ...
Tozzoli Renato - - 2008
CONTEXT: The reference limits for thyroid antibodies are generally made by measuring thyroid peroxidase and thyroglobulin antibody values in a group of healthy subjects (direct method), as proposed by the National Academy of Clinical Biochemistry. OBJECTIVE: To define the upper reference limits of thyroid peroxidase and thyroglobulin, by using an ...
Weinhaeusel Andreas - - 2008
BACKGROUND: RET germline mutations predispose to the development of hereditary medullary thyroid carcinoma (hMTC). Several single nucleotide polymorphisms (SNPs) are described associated with sporadic MTC (sMTC). However, the findings regarding their influence on the clinical course and biological behavior of this disorder are discordant. To clarify the contradictory findings, we ...
Ceresini Graziano - - 2009
To investigate thyroid function testing abnormalities in older persons and to explore the relationship between thyroid dysfunction and cognition. Cross-sectional. Community-based. One thousand one hundred seventy-one men and women aged 23 to 102. Thyroid function was evaluated by measuring plasma concentrations of thyrotropin (TSH), free thyroxine (FT4), and free triiodothyronine ...
Forestier E - - 2009
OBJECTIVE: Increased reverse tritiodothyronine (T(3)) used to be described as a part of euthyroid sick syndrome (ESS). It was demonstrated to be associated with increased mortality in acutely ill patients. It can also be found with low or normal T(3) in non-severely ill subjects but its significance remains unclear. PATIENTS ...
Ertugrul Derun T - - 2008
BACKGROUND AND AIM OF THE STUDY: Rheumatic mitral stenosis (RMS), an autoimmune sequel of streptococcal infection, causes significant morbidity and mortality. As Hashimoto's thyroiditis (HT) is recognized as the major form of chronic autoimmune thyroiditis, it was hypothesized that the coexistence of HT and RMS might have an autoimmune origin. ...
Rocha Eduardo M - - 2008
ABSTRACT The afferent nerves of the cornea and conjunctiva, efferent nerves of the lacrimal gland, and the lacrimal gland are a functional unit that works cooperatively to produce the aqueous component of tears. A decrease in the lacrimal gland secretory function can lead to dry eye disease. Because aging is ...
Milos Ioana N - - 2008
RET testing in multiple endocrine neoplasia type 2 for molecular diagnosis is the paradigm for the practice of clinical cancer genetics. However, precise data for distinct mutation-based risk profiles are not available. Here, we survey the clinical profile for one specific genotype as a model, TGC to TGG in codon ...
Langer Pavel - - 2008
In 137 females (F) and 94 males (M) aged 21-35 years from organochlorines (OCs) polluted area (POLL) increased thyroid volume (ThV), prevalence of antibodies to thyroperoxidase (TPOab), thyrotropin receptor (TRab) and of impaired fasting glucose (IFG) was found compared to 116 F and 107 M from background pollution area (BCGR). ...
Fujinami H - - 2008
BACKGROUND: Impaired salivary secretion has been reported to cause abnormal acid clearance from the oesophagus in gastro-oesophageal reflux disease (GERD). However, few studies have explained the differences between non-erosive reflux disease (NERD) and erosive oesophagitis (EO) with respect to salivary secretion. Aim To elucidate these differences, we measured salivary secretion ...
Boucai Laura - - 2009
OBJECTIVE: The suitability of TSH reference limits derived from national databases to outpatient practices has not been established. We aimed to determine whether race and age influence the distribution of TSH and free T4 (fT4). DESIGN: A cross-sectional study of an urban outpatient medical practice. PARTICIPANTS: Patients (n = 22,116) ...
Ljungvall Karl - - 2008
In a split-litter design experiment, male piglets were exposed orally three times weekly to 300 mg/kg of di(2-ethylhexyl) phthalate (DEHP) or placebo between three and seven weeks of age. The effects on the reproductive organs were examined immediately after the exposure at seven weeks of age in one sub-group, and ...
Conrey E J - - 2008
OBJECTIVES: Thyrotoxicosis is produced by excessive quantities of thyroid hormone. Its most common causes involve inflammation of the thyroid gland. Much more rarely, thyrotoxicosis is due to exogenous intake of thyroid hormones or iodide compounds. Few outbreaks are documented. In 2003 to early 2004, doctors in Minas, Uruguay noted a ...
Ochieng, J.
Background: Thymus gland is the only primary lymphoid organ in mammals, the first organ to become lymphoid and influences the development of other lymphoid organs in the body. It develops from the 3rd pharyngeal pouch in 5th week of intra uterine life and is located in the anterior and superior ...
Garvin Heather M - - 2008
As the role of forensic anthropologists expands to the medical examiner setting, their expertise is being applied beyond the traditional dry skeletal material. In such scenarios radiographic techniques can be applied when maceration is not appropriate. This study explores the use of radiographic analysis of laryngeal structures for age-at-death determination. ...
Jafary Fatemeh - - 2008
INTRODUCTION: Thyroid nodules not detected in palpation but diagnosed following a radiological procedure or during surgery are called thyroid incidentalomas. We designed this study to investigate the prevalence of sonographic thyroid incidentaloma in Isfahan, Iran, for the first time. MATERIAL AND METHODS: By a multistage cluster sampling method, 2523 adults ...
da Costa V M Corr?a - - 2008
The endocrine system is as affected by aging as are other systems. The effect of aging on the hypothalamus-pituitary-thyroid function is still controversial. Human aging was reported as associated with a decrease in thyrotropin (TSH) secretion, but increased TSH levels in relatively healthy elders are also reported. The main point ...
Patro Binod Kumar - - 2008
What is the current status of Iodine Deficiency Disorders (IDD) in the state of Jharkhand? (1) To determine the status of iodine deficiency in the state. (2) To determine the availability and cost of adequately iodized salt at the retail shops. (3) To study the perceptions of the community regarding ...
Köksal N - - 2008
BACKGROUND: The reference ranges of thyroid volumes in neonates vary according to the iodine status of a specific region. In different studies, it ranged between 0.47 and 1.62 ml. It has been previously shown that Bursa city was a moderately iodine-deficient area. We therefore aimed at determining normal reference ranges ...
Rai B - - 2008
Age estimation is an important aspect of forensic investigation and is considered as one of the "Big Four" of Forensic Anthropology. One hundred and twenty (120) cephalograms of individuals aged 7-20 years were examined with reference to mandibular body length (distance between Gonion and Gnathion) mandibular length (distance between Co ...
Korpal-Szczyrska Maria - - 2008
BACKGROUND: Thyroid hemiagenesis is a rare congenital anomaly in which one lobe of thyroid gland fails to develop. Because variations of the prevalence of this anomaly have been reported, the aim of this study was to evaluate the prevalence rate of thyroid hemiagenesis in an apparently normal population from Northern ...
Das Dilip Kumar DK RG Kar Medical College, West Bengal, India. - - 2008
We carried out a study to assess the prevalence of goitre, measure urinary iodine excretion (UIE) levels and to estimate salt iodine content at the household level in Howrah district of West Bengal, India. This is a Cross-sectional descriptive study conducted in September-December 2006. Primary schools located in 30 clusters ...
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