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Results 201 - 250 of 915
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Veres C - - 2010
The aim of this study is to define criteria for accurate representation of the thyroid in human models used to represent external beam radiotherapy (EBRT) patients and evaluate the relationship between the volume of this organ and clinical and anthropometric characteristics. From CT images, we segmented the thyroid gland and ...
Drozdovitch Vladimir V Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, 6120 Executive Boulevard, Bethesda, MD, 20892-7238, USA. - - 2011
The relationship between radiation exposure from nuclear weapons testing fallout and thyroid disease in a group of 2,994 subjects has been the subject of study by the US National Cancer Institute. In that study, radiation doses to the thyroid were estimated for residents of villages in Kazakhstan possibly exposed to ...
Santos M - - 2010
The development of the mammary gland is a puzzling phenomenon and the research on this field has been focussed mostly on the carcinogenesis, with a less goal-oriented concern in basic histology. In order to determine the histological features of normal mammary gland in the different oestrous phases we used 39 ...
Corsonello Andrea - - 2010
several studies suggest that a decreased thyroid activity might be favourable in oldest-old subjects and that subclinical thyroid hyperfunction may be detrimental. to verify whether declining levels of circulating thyroid hormones may contribute to longevity. cross-sectional observational study. all subjects were born in Calabria (southern Italy) and their ancestry in ...
Rozing M P - - 2010
A relation between low thyroid activity and prolonged life span in humans has been observed. Several studies have demonstrated hereditary and genetic influences on thyroid function. The objective of the study was to test whether low thyroid activity associated with extreme longevity constitutes a heritable phenotype, which could contribute to ...
Filipsson Nyström H - - 2010
Sweden has had a salt iodination program since 1936. This first national surveillance study on iodine nutrition infers an adequate level of urinary iodine concentration (UIC 125 μg/l) and the aim is now to evaluate thyroid volume (Tvol) in the same national sample. A stratified probability proportionate to size cluster sampling ...
Antico-Arciuch V G - - 2010
It is well known that thyroid disease is more frequent in women than in men; however, the molecular basis for this gender-based difference is still poorly understood. The activation of phosphoinositide 3-kinase (PI3K), through different mechanisms including loss of the PTEN tumor suppressor, is being increasingly recognized as a major ...
Aminorroaya Ashraf - - 2010
This cross-sectional study investigated the prevalence of goitre in Isfahan, a centrally-located city in Iran, 15 years after the initiation of universal salt iodization. In total, 2,523 Isfahani adults (1,275 males, 1,248 females) aged > 20 years were selected by multi-stage cluster-sampling method. Goitre rate, serum thyroid-stimulating hormone (TSH), thyroxine ...
Mao Yu-Shan - - 2010
The prevalence and the spectrum of thyroid dysfunction in the mainland of China are not adequately understood. We performed a population-based study to determine the prevalence of major thyroid dysfunctions including overt and subclinical hyper- and hypothyroidism in a stable cohort. All active and retired employees aged 20 years and ...
Trivedi Kalyani - - 2010
To determine the hard tissue surgical cephalometric norms statistically and geometrically in well-balanced faces having clinically acceptable facial profile in the Rajasthan population. To compare the cephalometric analyses of Rajasthanis males and females and to compare the craniofacial pattern of Rajasthani population with Caucasian norms. Lateral cephalograms of 200 subjects ...
Poiani Silvana Beani - - 2010
The cephalic salivary glands of some species of bees are exclusive and well developed only in Apinae. These glands were studied with light and scanning electron microscopy in workers, queens and males from the honey bee Apis mellifera, and the stingless bee Scaptotrigona postica in different life phases. The results ...
Over Rebecca - - 2010
Some studies suggest altered pituitary functioning and TSH production with aging. Our objective was to test the hypothesis that less TSH production occurs despite comparable hypothyroxinemia with advancing age. We retrospectively studied adult outpatients of all ages with confirmed hypothyroidism and documented their TSH and free T4 concentrations. Two populations ...
Putta-Manohar Sudeep - - 2010
Thyroid orbitopathy is a relatively rare disease. Prevalence data are lacking and can only be estimated. The incidence of thyroid orbitopathy has been documented in one American study (16 cases per 100,000 population per year for females and 2.9 cases per 100,000 population for males). Thyroid orbitopathy can affect every ...
Imani Elham Faghih - - 2010
INTRODUCTION: The aim of this study was to investigate the current status of sonographic characteristics of thyroid nodules in Isfahan, a previously iodine deficient area in central Iran. MATERIAL AND METHODS: In a cross-sectional study conducted in 2006, 2523 adult people (age > 20 years) were selected by a multistage ...
Su Pen-Hua - - 2010
Because placental polychlorinated dibenzo-p-dioxins,dibenzofurans (PCDD/Fs) levels are associated with decreased free thyroxine (FT(4)) and thyroid stimulating hormone (TSH) in neonates, we assessed development by gender and maternal PCDD/Fs exposure at years 2 and 5 in 92 mother and newborn pairs. RIA quantified thyroid, sex, and growth hormones. Of 200 subjects ...
de Freitas Clarice Umbelino - - 2010
BACKGROUND: Based on a suspicion raised by a health professional and due to a subsequent legal request, a cross-sectional study was made with a comparison group to investigate a possible excess of Hashimoto's thyroiditis-HT and antibodies-ATA in the surroundings of a Petrochemical Complex. METHODS: People of both sexes aged over ...
Keles Mustafa - - 2010
The purpose of this study was to evaluate the alterations in salivary gland function in patients who receiving continuous ambulatory peritoneal dialysis (CAPD) for chronic renal failure (CRF) using technetium-99m pertechnetate ((99m)Tc-P) salivary gland scintigraphy. The study population consisted of 36 CAPD patients (16 males and 20 females, ranging in ...
Ceresini Graziano - - 2010
Subclinical thyroid disease (STD) is defined as circulating concentrations of free T4 and free T3 within their respective reference ranges in the presence of abnormal circulating concentrations of TSH. SCD is being diagnosed more frequently in clinical practice and is reported to be more prevalent in elderly as compared to ...
Jafarzadeh Abdollah - - 2010
It has been reported that the immune system undergoes age and gender changes. The aim of this study was to investigate the age- and gender-dependent changes of salivary IgA and IgE levels among healthy subjects. A total of 203 healthy individuals (aged 1-70 years) were enrolled in the study. Two ...
Mihajlovski Agnès - - 2010
The methanogenic diversity of the human intestinal microbiota has long been viewed as composed of two Methanobacteriales: Methanobrevibacter smithii and Methanosphaera stadtmanae. Recently, Mx-01, a new phylotype hypothesized to belong to a putative sixth methanogenic order, was recovered from human faeces. Here we examined the diversity and the distribution of ...
Ermantas Nilay - - 2010
Hypothyroidism causes a tendency for cardiovascular diseases. It was recently shown that thrombin-activatable fibrinolysis inhibitor (TAFI) attenuates fibrinolysis and also fibrin-plasminogen interaction by the removal of lysine and arginine residues from fibrin monomers. The aim of this study was to determine the effects of overt hypothyroidism on the levels of ...
Rai B - - 2009
Age estimation is not only important for clinical but also for medico-legal purposes. The present study is an attempt to estimate the chronologic age based on the stages of third molar development following the eight stages (A-H) method of Demirjian et al8 and to compare third molar development by sex ...
Soldin Steven J - - 2010
We evaluated the clinical validity of serum FT4 measurements by assessing its correlation with log TSH. To provide pediatric reference intervals (representative ranges) for FT4, and TSH on the Architect ci8200 integrated system. This population-based study encompassed 6023 children (3369 females and 2654 males). The percentile and Hoffmann approaches for ...
Simonsick Eleanor M - - 2009
Health risks associated with subclinical hypothyroidism in older adults are unclear. Our objective was to compare the functional mobility of people aged 70 to 79 years by thyroid function categorized by thyrotropin (TSH) level as euthyroid (>or=0.4 to <4.5 mIU/L), mild subclinical hypothyroid (>or=4.5 to <7.0 mIU/L), or moderate subclinical ...
Terzidis K - - 2010
OBJECTIVES: Thyroid autoimmunity decreases in the very old. We investigated whether glucocorticoid (GC) activity, which increases in old age, is involved in this process. SUBJECTS AND METHODS: A total of 321 ambulatory subjects (age 51-95 years, median 71, 207 female) were studied. Thyroid function tests, cortisol, glucose, insulin and biochemical ...
Madeira Luciana Gonçalves - - 2010
Mechanisms accounting for sex-related differences in the sweat response remain to be elucidated. In the present study, we focused on differences in sweat gland cholinergic sensitivity between males and females. Since, males usually possess higher aerobic capacity than females, we investigated sweating in males and females grouped according to aerobic ...
Huang Chia-Chang - - 2010
Hypothyroidism is a common disorder in older people, and may be asymptomatic and hard to be diagnosed. The main purpose of this study was to evaluate the distribution of serum thyrotropin (thyroxin-stimulating hormone, TSH) among asymptomatic older people in Taiwan, and to evaluate the relationship between age and serum TSH. ...
Schell Lawrence M - - 2010
Endocrine disruption has become a significant human health concern, but is difficult to study outside of the laboratory for several reasons including the multiplicity of exposures, the difficulty in assessing each exposure, and the variety of possible outcomes among human populations. This review summarizes our studies of the relationships of ...
Wilsher S - - 2009
Fillies completely devoid of endometrial glands (uterine gland knockout; UGKO) would make ideal experimental models in which to study the role of endometrial histotroph in embryogenesis and early fetal development in the mare. Administration of a synthetic progestagen plus oestrogen to newborn filly foals and, thereafter, at regular intervals to ...
Pereira C P M - - 2009
The present study analyzed the effects of the chemical compound fipronil, active ingredient of Frontline (acaricide and insecticide), on the salivary glands of unfed and semi-engorged female Rhipicephalus sanguineus tick. Unfed females were only exposed to the concentration of 1 ppm of fipronil, while semi-engorged females were treated with fipronil ...
Guth S - - 2009
BACKGROUND: The prevalence of thyroid nodules in a healthy population is high: in the German Papillon study, nationwide ultrasound screening of more than 90 000 people using 7.5 MHz scanners revealed the presence of thyroid nodules in 33% of the normal population. A study employing more sensitive 13 MHz scanners ...
McCann Louise C - - 2009
PURPOSE: To determine the differential features of tear physiology and meibomian gland function in blepharitics for ascertaining the diagnostic potential of a number of clinical tests. METHODS: Two groups of subjects, 15 with clinically diagnosed blepharitis (11 women and 5 men mol/L; age 60.9 +/- 12.5; range 41-79) and 15 ...
Valeix Pierre - - 2009
OBJECTIVE: To assess dietary iodine intakes among adults and to investigate the relationships of dietary, lifestyle, demographic and geographical characteristics with dietary iodine status. Adequacy of iodine intakes was also assessed. DESIGN: Cross-sectional study. Linear regression analyses and logistic regression modelling were used to determine correlates of iodine intakes. Usual ...
Gatseva P D - - 2009
OBJECTIVES: To assess the effectiveness of iodine prophylaxis in schoolchildren, living in a rural area in South Bulgaria, after the introduction of salt iodization. STUDY DESIGN: The study subjects were 114 schoolchildren (59 boys and 55 girls), aged 11-14 years, living in a rural area in Bulgaria. Urinary iodine concentration ...
Tenpenny K Elliott - - 2009
OBJECTIVE: To investigate reports of iodine-deficiency disorder in a specific area of Haiti. METHODS: In March 2008, this cross-sectional study was performed in an area 15 miles northeast of Jacmel, Haiti, within the Cha?ne de la Selle Mountains. Before arrival of the study team, an announcement was made throughout local ...
Kilfoy Briseis A - - 2009
Thyroid cancer incidence rates have increased worldwide for decades, although more for papillary carcinomas than other types and more for females than males. There are few known thyroid cancer risk factors except female gender, and the reasons for the increasing incidence and gender differences are unknown. We used the National ...
Haymart Megan R - - 2009
Unique among malignancies, age is a key prognostic indicator for well-differentiated thyroid cancer. Patients aged <45 years can have the same degree of disease involvement and a distinctly different prognosis than those aged >45. Although the reason for the association between age and outcome is not entirely clear, it does ...
Severinski Srećko - - 2009
The aim of the study was to evaluate the natural course and potential risk factors of autoimmune thyroiditis (AIT) and thyroid dysfunction, and their influences on growth and glycemic control in children and adolescents with type 1 diabetes mellitus (T1D). The study comprised 148 subjects (age range 1-21 years; males ...
Bayram F - - 2009
BACKGROUND: The prevalence of goitre and urinary iodine excretion (UIE) indicate endemic iodine deficiency (ID) in a population. Previous studies have shown that Kayseri is one of the most iodine-deficient areas in Turkey. The aim of this study was to determine the prevalence of goitre, evaluate the degree of ID, ...
Usha Menon V - - 2009
India is in the transition phase from iodine deficiency to iodine sufficiency, and this is expected to change the thyroid status of the population. The thyroid status and auto-immune status of adult Indian population in the postiodisation phase is largelyunknown, and this study was conducted to answer this question. A ...
Magnanti Brooke L - - 2009
A previous study found a thyroid cancer excess in Cumbria following the Chernobyl explosion, but did not analyse sex-specific effects. This study examines sex differences in the incidence of thyroid cancer. Ninety-five primary thyroid carcinomas (69 females, 26 males) diagnosed in those aged 0-24 during 1968-2005 were identified from the ...
Atzmon Gil - - 2009
The distribution of serum TSH shifts progressively to higher concentrations with age. The aim of the study was to determine whether the population shift in TSH distribution to higher concentrations with aging extends to people of exceptional longevity, namely centenarians, and to assess the relationship between concentrations of TSH and ...
Estaquio Carla - - 2009
BACKGROUND: The goal of this study was to provide reference ranges for thyrotropin (TSH) and free thyroxine (fT(4)) based on data collected from a disease-free sample of French middle-aged adults. METHODS: A total of 3218 subjects participating in the Suppl??mentation en Vitamines et Min??raux Antioxydants (SU.VI.MAX) study had measurements for ...
Bhansali Anil - - 2009
Precocious puberty in a child less than 3 years of age is usually gonadotropin dependent and is often associated with extrasellar central nervous system disorders. The present report describes the case of a 2½-year-old girl who presented with gonadotropin-independent precocious puberty and had a sellar mass. She was referred for ...
Nemolato Sonia - - 2009
Thymosin beta(4), its sulfoxide, and thymosin beta(10) were detected in whole saliva of human pre-term newborns by reversed-phase high performance chromatography coupled to electrospray ion-trap mass spectrometry. Despite high inter-individual variability, concentration of beta-thymosins increases with an inversely proportional trend to postmenstrual age (PMA: gestational age plus chronological age after ...
Nishimaki Momoko - - 2009
Painless thyroiditis is characterized by transient thyrotoxicosis with complete recovery. Some patients, however, have repeated episodes of thyrotoxicosis, for which the mechanism of recurrence is not clear. We therefore studied the clinical characteristics in 8 patients with 4 or more episodes of thyrotoxicosis and 40 control patients. The age at ...
Gautron Laurent - - 2009
The pituitary gland undergoes important changes in cellular plasticity throughout life, consequently leading to hormonal output changes. The intermediate filament nestin plays a crucial role in cells that retain plasticity during development, aging and tumorigenesis. Here, we describe robust nestin immunoreactivity in glial-like cells of the intermediate lobe and in ...
Paz-Filho Gilberto - - 2009
: Thyroid function is closely related to leptin's secretion by the adipose tissue. In states of leptin-deficiency, the circadian rhythm of TSH is altered, leading to central hypothyroidism in animal models. In humans, central hypothyroidism has also been described in rare cases of congenital leptin deficiency. However, the thyroid phenotype ...
Vejbjerg Pernille - - 2009
OBJECTIVE: Marked differences in pattern of thyroid dysfunction are seen in populations with different iodine intakes. We evaluated the influence of a higher iodine intake on thyroid hormone levels and the prevalence of thyroid dysfunction in the Danish population. DESIGN: Two cross-sectional studies matched on a group level according to ...
Tozzoli Renato - - 2008
CONTEXT: The reference limits for thyroid antibodies are generally made by measuring thyroid peroxidase and thyroglobulin antibody values in a group of healthy subjects (direct method), as proposed by the National Academy of Clinical Biochemistry. OBJECTIVE: To define the upper reference limits of thyroid peroxidase and thyroglobulin, by using an ...
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