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Rapaić Dragan - - 2014
There are almost no studies on apraxia in people with multiple sclerosis. Although the white matter is damaged in MS, it is not the only location in which the pathological changes are present. Demyelinated lesions in the cortex have recently been recognized as important components of multiple sclerosis pathology. The ...
Shinkov A A Department of Thyroid and Bone Mineral Diseases, University Hospital of Endocrinology, Medical University of Sofia, Sofia, - - 2014
Background/objectives:To study the relationship of winter 25-hydroxycholecalciferol (25-OHD) levels with age, education, place of residency, marital status and body mass index (BMI) as they may affect sun exposure, vitamin D synthesis and metabolism.Subjects/methods:Subjects (1952) answered a structured questionnaire concerning education, marital status and smoking; and body weight/height, and parathyroid hormone ...
Mézière Anthony A Assistance Publique - Hôpitaux de Paris, Groupe Hospitalier Universitaire La Pitié Salpêtrière - Charles Foix, SSR Orthogériatrique, Fondation d'Heur et Chemin Delatour, Ivry sur Seine, France. Département de Gériatrie - - 2014
Cobalamin deficiency is responsible for hematological, neurological, neurocognitive, and neuropsychiatric impairments and is a risk factor for cardiovascular diseases, particularly in the elderly people. In order to determine B12 status in old inpatients, a total number of 14,904 hospitalized patients in whom B12 measurements were performed in five hospitals in ...
Serwin Agnieszka B AB Department of Dermatology and Venereology, Medical University of Bialystok, Bialystok, - - 2014
Bullous pemphigoid (BP) is the most frequently encountered autoimmune blistering disorder, affecting mainly elderly population. The aim of the study was to assess the incidence of BP in Podlaskie Province (north-east Poland) in 1999-2012, socio-demographic characteristics and mortality of patients with BP. The number of newly diagnosed (in two regional ...
Valbuena Martha C MC Photodermatology Unit, Centro Dermatológico Federico Lleras Acosta, Avda. 1 No. 13A-61, Bogotá, Colombia. Electronic address: - - 2014
Actinic prurigo is a chronic photodermatosis with onset in childhood or before 20 years of age. It is most prevalent in Amerindians and Latin American mestizos, although it has been reported worldwide. Patients present with photodistributed, erythematous excoriated papules, cheilitis, and conjunctivitis. There is strong association with human leukocyte antigen ...
El-Khateeb Mohammed M National Center for Diabetes, Endocrinology and Genetics, Amman, - - 2014
Background: Vitamin B12 deficiency is highly prevalent worldwide and has been linked to hematologic, neurologic and psychiatric diseases. There are a few studies regarding vitamin B12 deficiency in developing countries in general and in Jordan in particular. Objectives: The aims of the present study were to assess the vitamin B12 ...
Lee Yong-Ho YH Division of Endocrinology and Metabolism (Y.L., J.E.K., Y.R., S.-K.L.), Department of Internal Medicine, Graduate School (Y.L., J.E.K., Y.R., S.-K.L.), and Biostatistics Collaboration Unit (Y.H.R., D.R.K.), Yonsei University College of Medicine, Seoul 120-752, Korea; and Division of Cardiovascular and Rare Disease (H.R.C.), National Institute of Health, Osong 363-951, - - 2014
Context: Although mild to moderate chronic kidney disease (CKD) and vitamin D deficiency are prevalent in the elderly population worldwide and are associated with sarcopenia, their influence on bone mineral density (BMD) has not been determined. Objective: The objective of the study was to determine the combined effects of vitamin ...
Sidonio Robert F RF Jr Vanderbilt University Medical Center, Monroe Carell Jr. Children's Hospital at Vanderbilt, 2220 Pierce Avenue, 392 Preston Research Building, Nashville, TN, - - 2014
Little is known about rates of joint bleeding among females with FVIII/FIX deficiency or hemophilia carriers. In a cross-sectional study, we tested the hypothesis that females with FVIII or FIX deficiency enrolled in the Universal Data Collection (UDC) project had a reduced mean overall joint range of motion (ROM) compared ...
Shrira Amit A a Interdisciplinary Department of Social Sciences , Faculty of Social Sciences , Bar-Ilan University , Ramat-Gan , - - 2014
Objectives: Subjective age refers to how young or old people experience themselves to be, while subjective distance-to-death reflects how far or close they experience themselves to be from their death. The present study examined whether subjective age and subjective distance-to-death interact in predicting psychological distress.Method: A sample of 1073 community-dwelling ...
Ross I L IL Division of Endocrinology, Department of Medicine, University of Cape Town, Cape Town, South - - 2014
Hypogonadism may complicate Addison's disease (primary hypoadrenalism), but prevalence and metabolic sequelae of hypogonadism in Addison's disease are poorly described. We recruited patients from the South African Addison's disease national registry who received stable replacement doses of hydrocortisone and had no acute illness. Male biochemical testosterone deficiency was defined as ...
Restell Tamy Ingrid TI Federal University of Mato Grosso do Sul, Campo Grande, MS, - - 2014
To describe the hematologic values of male and female, young and adult, Swiss mice (Mus musculus). Mus musculus (n=14) were randomly selected and separated by gender. The male and female, young and adult animals were sedation to obtain a blood sample, by intracardiac route at 30, 45, 60, 75, 90, ...
Quaggiotto P P Department of Clinical Chemistry, Hunter Area Pathology Service, John Hunter Hospital, Locked Bag 1, Hunter Region Mail Centre, New South Wales 2310, Australia. - - 2014
The aim of the present study was to assess the prevalence of vitamin D deficiency and toxicity, the frequency of 25-hydroxyvitamin D (25[OH]D) testing, and 25(OH)D variations with respect to patient gender, patient age and season in New South Wales, Australia. A retrospective analysis of pathology records was performed to ...
Alcalay Roy N RN The Taub Institute, Department of Neurology, Columbia University Medical Center, New York, New - - 2014
IMPORTANCE Information on age-specific risk for Parkinson disease (PD) in patients with Gaucher disease (GD) and glucocerebrosidase (GBA) heterozygotes is important for understanding the pathophysiology of the genetic association and for counseling these populations. OBJECTIVE To estimate the age-specific risk for PD in Ashkenazi Jewish patients with type 1 GD ...
Cabral Renan Desimon RD Urology Department, Hospital de Clínicas de Porto Alegre, Federal University of Rio Grande do Sul , Porto Algre , - - 2014
Abstract Objective: At present, calculated free testosterone assessment is considered as the gold standard in diagnosing male hypogonadism. However, this assessment is not available for all the individuals diagnosed with decreased testicular function. The investigators of this study were, thus, prompted to evaluate whether the androgen deficiency in the aging ...
Zhang Sheng S Key Laboratory of Mountain Surface Processes and Ecological Regulation, Institute of Mountain Hazards and Environment, Chinese Academy of Sciences, Chengdu 610041, - - 2014
Previous studies have shown that there are significant sexual differences in the morphological and physiological responses of Populus cathayana Rehder under stressful conditions. However, little is known about sex-specific differences in responses to nutrient deficiencies. In this study, the effects of nitrogen (N) and phosphorus (P) deficiencies on the morphological, ...
Taksler Glen B GB 1 Medicine Institute, Cleveland Clinic, 9500 Euclid Avenue, G1-40F, Cleveland, OH 44195, - - 2014
Black and Hispanic individuals synthesize less vitamin D per unit of sun exposure than white individuals. The relationship between UV radiation and vitamin D insufficiency in minorities has not been well explored. Prospective cohort study. Using the National Health and Nutrition Examination Survey, we obtained serum vitamin D levels for ...
Vanbuskirk Kelley M KM Policy Planning Monitoring and Evaluation Division, Ghana Health Service, Accra, - - 2014
Objective: To assess anemia prevalence and identify associated parameters in children <3 years of age in a rural area of Ghana.Method: Univariate and multivariate logistic regression of cross-sectional survey results from 861 children aged <3 years attending routine immunization services in Berekum district.Results: Anemia prevalence was 73.1%; most were either ...
Walsh Kyle M KM Division of Neuroepidemiology, Department of Neurological Surgery, University of California, San Francisco, San Francisco, CA, 94143, USA; Program in Cancer Genetics, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA, 94143, - - 2014
Background: Hispanic children have a higher incidence of acute lymphoblastic leukemia (ALL) than non-Hispanic whites, but tend to be diagnosed at older ages. In genome-wide association studies, Native American ancestry and polymorphisms in six genes have been associated with ALL risk. Methods: In multivariable regression models, we investigated whether genomic ...
Dees Elise W - - 2014
Carriers of red-green color-vision deficiencies are generally thought to behave like normal trichromats, although it is known that they may make errors on Ishihara plates. The aim here was to compare the performance of carriers with that of normal females on seven standard color-vision tests, including Ishihara plates. One hundred ...
Pandey Kanti Bhooshan KB Department of Biochemistry, University of Allahabad, Allahabad - - 2014
Implication of reactive oxygen species/oxidative stress has been readily reported in etiology of aging and related manifestations. Plasma membrane as a regulator of numerous aspects of cell physiology including cell-cell interaction, solute transport, and signal transduction, provides structural integrity to the cells. The aim of the present study was to ...
Li Fangting F Department of Ophthalmology, Peking University People's Hospital, Beijing, - - 2014
Purpose: To analyze the association between ABCA1 rs1883025 variants with neovascular age-related macular degeneration (nAMD) and polypoidal choroidal vasculopathy (PCV) in a northern Chinese population. Methods: The study enrolled 900 subjects, including 300 controls, 300 cases with nAMD and 300 cases with PCV. Genomic DNA was extracted from venous blood ...
von Fricken Michael E ME Emerging Pathogens Institute, University of Florida, 2055 Mowry Road, Gainesville, Florida 32610; Department of Environmental and Global Health, University of Florida, PO Box 100188, Gainesville, Florida 32610. Electronic address: - - 2014
Malaria remains a significant public health issue in Haiti, with chloroquine (CQ) used almost exclusively for the treatment of uncomplicated infections. Recently, single dose primaquine (PQ) was added to the Haitian national malaria treatment policy, despite a lack of information on the prevalence of glucose-6-phosphate dehydrogenase (G6PD) deficiency within the ...
Ramiro Sofia S Department of Clinical Immunology & Rheumatology, Amsterdam Rheumatology Center, University of Amsterdam, Amsterdam, The - - 2014
To establish reference intervals (RIs) for spinal mobility measures as recommended for patients with axial spondyloarthritis, and to determine the effect of age, height and gender on spinal mobility, in normal individuals. A cross-sectional study (MOBILITY) was conducted among normal individuals aged 20-69 years. Recruitment was stratified by gender, age ...
Jafarzadehpur Ebrahim E Department of Optometry, Tehran University of Medical Sciences, Tehran, - - 2014
The aim of this study was to determine the prevalence of color vision defects in the middle-age population of Shahroud, Iran. We selected 6,311 people from the 40- to 64-year-old population through random cluster sampling. Color vision testing was performed with the Farnsworth D-15. Cases with similar and symmetric results ...
Kim Min Jung MJ School of Mechanical Engineering, Korea University, Anam-dong, Seongbuk-gu, Seoul, Republic of Korea - - 2014
Rapid developments in the food applications of silver nanomaterials (Ag-NMs) have resulted in concerns related to the risk of overexposure of human blood. We investigated the effect of size and aspect ratio of Ag-NMs on rheological characteristics of human erythrocytes, including hemolysis, deformability, aggregation, and morphological changes. Red blood cells ...
Jaganath Devan D 1 David Geffen School of Medicine at UCLA , Los Angeles, - - 2014
Abstract Given the detrimental effects of HIV-associated anemia on morbidity, we determined factors associated with anemia after 96 weeks of antiretroviral therapy (ART) across age groups. An HIV-positive cohort (n=3,580) of children age 5-14, reproductive age adults 18-49, and older adults ≥50 from two randomized trials in Uganda and Zimbabwe ...
Hussain Riaz R University College of Veterinary and Animal Sciences, The Islamia University of Bahawalpur, Bahawalpur 63000, Pakistan. Electronic address: - - 2014
The present experiment was executed to determine the pathological effects induced by concurrent feeding of butachlor (chloroacetanilide herbicide) in male Japanese quail. For this purpose mature male quail about 4-5weeks of age were procured from the local market and randomly divided into six equal groups (A-F). Butachlor was mixed in ...
Dolka B B Department of Pathology and Veterinary Diagnostics, Faculty of Veterinary Medicine, Warsaw University of Life Sciences (WULS-SGGW), Nowoursynowska 159c St., 02-776, Warsaw, Poland, - - 2014
The knowledge of the correct morphological and biochemical parameters in mute swans is an important indicator of their health status, body condition, adaptation to habitat and useful diagnostic tools in veterinary practice and ecological research. The aim of the study was to obtain hematological parameters in relation to age, sex ...
Oh Se Won SW Department of Internal Medicine, Eulji General Hospital, Eulji University College of Medicine, Seoul, - - 2014
Obesity is a risk factor for chronic kidney disease, and its prevalence among the elderly is increasing. We investigated the effects of changes in body fat percentage (BFP) on the longitudinal changes in the estimated glomerular filtration rate (eGFR) in the elderly. This prospective cohort study included 390 participants aged ...
Karkouti Keyvan K Department of Anesthesia and Pain Management, Toronto General Hospital, University Health Network, University of Toronto, 200 Elizabeth St. 3EN, Toronto, ON, M5G 2C4, Canada, - - 2014
Purdy FR, Tweeddale MG, Merrick PM. Can J Anaesth 1997; 44: 1256-61. This retrospective observational study was performed to determine if the age of transfused units of red blood cells (RBCs) was related to mortality. The study included 31 transfused patients admitted to the intensive care unit during 1992 with ...
Prado-Barreto Valéria M VM Division of Otorhinolaryngology, Federal University of Sergipe, Aracaju, Sergipe, - - 2014
ObjectiveTo evaluate the hearing status of growth hormone (GH)-naive adults with isolated GH deficiency (IGHD) belonging to an extended Brazilian kindred with a homozygous mutation in the GH-releasing hormone receptor gene.Study DesignCross-sectional.SettingDivisions of Endocrinology and Otorhinolaryngology of the Federal University of Sergipe.Subjects and MethodsTwenty-six individuals with IGHD (age, 47.6 ± ...
Aydinonat Denise D Department of Biomedical Sciences, Biochemistry, University of Veterinary Medicine, Vienna, Austria; Department of Integrative Biology and Evolution, Konrad Lorenz Institute of Ethology, University of Veterinary Medicine, Vienna, - - 2014
Telomeres, the caps of eukaryotic chromosomes, control chromosome stability and cellular senescence, but aging and exposure to chronic stress are suspected to cause attrition of telomere length. We investigated the effect of social isolation on telomere length in the highly social and intelligent African Grey parrot (Psittacus erithacus erithacus). Our ...
Anitha Palaniyandi P Sri Ramachandra Medical College and Research Institute, Chennai, Tamil Nadu, - - 2014
Deficiency of vitamin B12 (cobalamin) is a well-known cause of megaloblastic anaemia. It is a reversible cause of bone marrow failure and demyelinating nervous system disorder, hence early detection and prompt treatment of vitamin B12 deficiency is essential. After diagnosing vitamin B12 deficiency, tracking down its root cause is important ...
Clement Nicholas David ND Department of Orthopaedics and Trauma, The Royal Infirmary of Edinburgh, Little France, Edinburgh, - - 2014
The function of the asymptomatic normal shoulder may differ according to gender and could also deteriorate with age. This may result in a disparity in the normal Oxford shoulder score (OSS) according to these variables. If a difference were to exist an adjusted OSS, for age and gender, could be ...
Guo Ting T Center for Reproductive Medicine, Shandong Provincial Hospital Affiliated to Shandong University, Shandong University, National Research Center for Assisted Reproductive Technology and Reproductive Genetics, The Key laboratory for Reproductive Endocrinology of Ministry of Education, Shandong Provincial Key Laboratory of Reproductive Medicine, Jinan, - - 2014
In premature ovarian failure (POF), cessation of menstruation occurs before the expected age of menopause. Approximately 1% of women are affected. FMR1 premutation was reported to be responsible for up to 3.3%-6.7% of sporadic POF and 13% of familial cases in Caucasians, while the data was absent in Chinese population. ...
Harisa Gamaleldin I GI Department of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia; Department of Biochemistry, College of Pharmacy, Al-Azhar University (Boys), Nasr City, Cairo, Egypt. - - 2013
In this study, the protective role of naringin (NAR) against paclitaxel (PTX)-induced erythrocytes aging has been investigated using human erythrocyte as an in vitro model. Erythrocytes were incubated with PTX in the presence and absence of NAR. Incubation of erythrocytes with PTX resulted in increased protein carbonyl content and malondialdehyde ...
Mok Kin Y KY Department of Molecular Neuroscience , UCL Institute of Neurology, Queen Square, London, UK; Reta Lila Weston Institute, UCL Institute of Neurology, London, UK. Electronic address: - - 2013
It is known that Alzheimer's disease (AD) presents at an early age in people with Down syndrome (DS). The trisomy 21 in DS provides an opportunity to study the effect of duplicated genes in AD. APP and BACE2 are 2 genes located in chromosome 21 and related to AD. We ...
Bergfeld Wilma F - - 2013
A young female child aged 7 years presented initially with chronic alopecia areata, which over 2 years progressed to alopecia areata universalis.
Uysal Recep - - 2013
This study examined the mediating effects of Facebook addiction on the relationship between subjective vitality and subjective happiness. 297 university students (157 women, 140 men; M age = 20.1 yr., SD = 1.3) were administered the Facebook Addiction Scale, the Subjective Vitality Scale, and the Subjective Happiness Scale. Hierarchical regression ...
Singh Parminder P Division of Endocrinology, Dayanand Medical College and Hospital, Ludhiana, Punjab, - - 2013
Andropause or late-onset hypogonadism is a common disorder which increases in prevalence with advancing age. Diagnosis of late-onset of hypogonadism is based on presence of symptoms suggestive of testosterone deficiency - prominent among them are sexual symptoms like loss of libido, morning penile erection and erectile dysfunction; and demonstration of ...
Pelegrín Laura - - 2013
Abstract Purpose: Uveitis is the most common extra-articular manifestation of juvenile idiopathic arthritis (JIA) and is associated with considerable morbidity. The aim of this study was to examine the risk factors associated with uveitis in oligoarticular JIA. Methods: We conducted a chart review of 86 patients with oligoarticular JIA to ...
Liu Yao-Wen - - 2013
A673T, a rare variant in the amyloid-β precursor protein gene, shows a protective potential against Alzheimer's disease (AD) and age-related cognitive decline in an Icelandic population. Although A673T was observed independently in a Finnish population, this variant was absent in 8721 Asian subjects. The conflicting observations suggest that the contribution ...
Joustra S D SD MD, Department of Endocrinology and Metabolism C7-Q, Leiden University Medical Center, P.O. Box 9600, 2300 RC Leiden, The Netherlands. - - 2013
Ig superfamily member 1 (IGSF1) deficiency was recently discovered as a novel X-linked cause of central hypothyroidism (CeH) and macro-orchidism. However, clinical and biochemical data regarding growth, puberty, and metabolic outcome, as well as features of female carriers, are scarce. Our objective was to investigate clinical and biochemical characteristics associated ...
Weingarz Lea - - 2013
Thrombophilia is a well-established risk factor for a venous thromboembolic event (VTE), and it has been proposed that hereditary thrombophilia may substantially contribute to the development of VTE in young patients. We aimed to analyse the prevalence of thrombophilia with special regard to the age of VTE manifestation. The study ...
Kaukonen Kirsi-Maija - - 2013
Transfusion of red blood cells (RBCs) and, in particular, older RBCs has been associated with increased short-term mortality in critically ill patients. We evaluated the association between age of transfused RBCs and acute kidney injury (AKI), hospital, and 90-day mortality in critically ill patients. We conducted a prospective, observational, predefined ...
Patil Santosh S Dept of Oral medicine and radiology, Jodhpur Dental College, Jodhpur National University, Jodhpur (Raj), - - 2013
Taurodontism affects primarily molars and premolars in both the deciduous and permanent dentition. The aim of the study was to assess the prevalence of taurodontism in the North Indian population. 4143 patients were studied by analyzing the panoramic radiographs for the presence of taurodontism which is defined as the presence ...
Ghashghaeinia Mehrdad - - 2013
Background/Aims: Erythrocytes may enter eryptosis, a suicidal death characterized by cell shrinkage and phosphatidylserine exposure at the erythrocyte outer membrane. Susceptibility to eryptosis is enhanced in aged erythrocytes and stimulated by NFκB-inhibitors Bay 11-7082 and parthenolide. Here we explored whether expression of NFκB and susceptibility to inhibitor-induced eryptosis is sensitive ...
Deckers M M L - - 2013
Reference values of PTH depend on vitamin D status of the reference population. This is often not described in package inserts. The aim of the present study was therefore to calculate assay specific PTH reference levels in EDTA plasma for the Architect (Abbott) in relation to 25-hydroxyvitamin D (25OHD) levels. ...
Franchi Franca - - 2013
Antithrombin (AT), protein C (PC) and protein S (PS) deficiencies are risk factors for venous thromboembolism. Overlapping values between heterozygous carriers and normal individuals often make a correct classification of a deficiency difficult. The aim of this study was to investigate the effect of sex, age, menopause and hormone therapy ...
Audenet François - - 2013
Few risk factors are identified for Renal Cell Carcinoma (RCC). The purpose of this work was to perform a validation study on a population of European background for the most significant variants previously identified in association with RCC risk. We conducted a case-control validation study by recruiting 463 controls and ...
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