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Cabral Renan Desimon RD Urology Department, Hospital de Clínicas de Porto Alegre, Federal University of Rio Grande do Sul , Porto Algre , - - 2014
Abstract Objective: At present, calculated free testosterone assessment is considered as the gold standard in diagnosing male hypogonadism. However, this assessment is not available for all the individuals diagnosed with decreased testicular function. The investigators of this study were, thus, prompted to evaluate whether the androgen deficiency in the aging ...
Zhang Sheng S Key Laboratory of Mountain Surface Processes and Ecological Regulation, Institute of Mountain Hazards and Environment, Chinese Academy of Sciences, Chengdu 610041, - - 2014
Previous studies have shown that there are significant sexual differences in the morphological and physiological responses of Populus cathayana Rehder under stressful conditions. However, little is known about sex-specific differences in responses to nutrient deficiencies. In this study, the effects of nitrogen (N) and phosphorus (P) deficiencies on the morphological, ...
Vanbuskirk Kelley M KM Policy Planning Monitoring and Evaluation Division, Ghana Health Service, Accra, - - 2014
Objective: To assess anemia prevalence and identify associated parameters in children <3 years of age in a rural area of Ghana.Method: Univariate and multivariate logistic regression of cross-sectional survey results from 861 children aged <3 years attending routine immunization services in Berekum district.Results: Anemia prevalence was 73.1%; most were either ...
Walsh Kyle M KM Division of Neuroepidemiology, Department of Neurological Surgery, University of California, San Francisco, San Francisco, CA, 94143, USA; Program in Cancer Genetics, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA, 94143, - - 2014
Background: Hispanic children have a higher incidence of acute lymphoblastic leukemia (ALL) than non-Hispanic whites, but tend to be diagnosed at older ages. In genome-wide association studies, Native American ancestry and polymorphisms in six genes have been associated with ALL risk. Methods: In multivariable regression models, we investigated whether genomic ...
Dees Elise W - - 2014
Carriers of red-green color-vision deficiencies are generally thought to behave like normal trichromats, although it is known that they may make errors on Ishihara plates. The aim here was to compare the performance of carriers with that of normal females on seven standard color-vision tests, including Ishihara plates. One hundred ...
Li Fangting F Department of Ophthalmology, Peking University People's Hospital, Beijing, - - 2014
Purpose: To analyze the association between ABCA1 rs1883025 variants with neovascular age-related macular degeneration (nAMD) and polypoidal choroidal vasculopathy (PCV) in a northern Chinese population. Methods: The study enrolled 900 subjects, including 300 controls, 300 cases with nAMD and 300 cases with PCV. Genomic DNA was extracted from venous blood ...
von Fricken Michael E ME Emerging Pathogens Institute, University of Florida, 2055 Mowry Road, Gainesville, Florida 32610; Department of Environmental and Global Health, University of Florida, PO Box 100188, Gainesville, Florida 32610. Electronic address: - - 2014
Malaria remains a significant public health issue in Haiti, with chloroquine (CQ) used almost exclusively for the treatment of uncomplicated infections. Recently, single dose primaquine (PQ) was added to the Haitian national malaria treatment policy, despite a lack of information on the prevalence of glucose-6-phosphate dehydrogenase (G6PD) deficiency within the ...
Ramiro Sofia S Department of Clinical Immunology & Rheumatology, Amsterdam Rheumatology Center, University of Amsterdam, Amsterdam, The - - 2014
To establish reference intervals (RIs) for spinal mobility measures as recommended for patients with axial spondyloarthritis, and to determine the effect of age, height and gender on spinal mobility, in normal individuals. A cross-sectional study (MOBILITY) was conducted among normal individuals aged 20-69 years. Recruitment was stratified by gender, age ...
Jafarzadehpur Ebrahim E Department of Optometry, Tehran University of Medical Sciences, Tehran, - - 2014
The aim of this study was to determine the prevalence of color vision defects in the middle-age population of Shahroud, Iran. We selected 6,311 people from the 40- to 64-year-old population through random cluster sampling. Color vision testing was performed with the Farnsworth D-15. Cases with similar and symmetric results ...
Kim Min Jung MJ School of Mechanical Engineering, Korea University, Anam-dong, Seongbuk-gu, Seoul, Republic of Korea - - 2014
Rapid developments in the food applications of silver nanomaterials (Ag-NMs) have resulted in concerns related to the risk of overexposure of human blood. We investigated the effect of size and aspect ratio of Ag-NMs on rheological characteristics of human erythrocytes, including hemolysis, deformability, aggregation, and morphological changes. Red blood cells ...
Jaganath Devan D 1 David Geffen School of Medicine at UCLA , Los Angeles, - - 2014
Abstract Given the detrimental effects of HIV-associated anemia on morbidity, we determined factors associated with anemia after 96 weeks of antiretroviral therapy (ART) across age groups. An HIV-positive cohort (n=3,580) of children age 5-14, reproductive age adults 18-49, and older adults ≥50 from two randomized trials in Uganda and Zimbabwe ...
Hussain Riaz R University College of Veterinary and Animal Sciences, The Islamia University of Bahawalpur, Bahawalpur 63000, Pakistan. Electronic address: - - 2014
The present experiment was executed to determine the pathological effects induced by concurrent feeding of butachlor (chloroacetanilide herbicide) in male Japanese quail. For this purpose mature male quail about 4-5weeks of age were procured from the local market and randomly divided into six equal groups (A-F). Butachlor was mixed in ...
Dolka B B Department of Pathology and Veterinary Diagnostics, Faculty of Veterinary Medicine, Warsaw University of Life Sciences (WULS-SGGW), Nowoursynowska 159c St., 02-776, Warsaw, Poland, - - 2014
The knowledge of the correct morphological and biochemical parameters in mute swans is an important indicator of their health status, body condition, adaptation to habitat and useful diagnostic tools in veterinary practice and ecological research. The aim of the study was to obtain hematological parameters in relation to age, sex ...
Oh Se Won SW Department of Internal Medicine, Eulji General Hospital, Eulji University College of Medicine, Seoul, - - 2014
Obesity is a risk factor for chronic kidney disease, and its prevalence among the elderly is increasing. We investigated the effects of changes in body fat percentage (BFP) on the longitudinal changes in the estimated glomerular filtration rate (eGFR) in the elderly. This prospective cohort study included 390 participants aged ...
Karkouti Keyvan K Department of Anesthesia and Pain Management, Toronto General Hospital, University Health Network, University of Toronto, 200 Elizabeth St. 3EN, Toronto, ON, M5G 2C4, Canada, - - 2014
Purdy FR, Tweeddale MG, Merrick PM. Can J Anaesth 1997; 44: 1256-61. This retrospective observational study was performed to determine if the age of transfused units of red blood cells (RBCs) was related to mortality. The study included 31 transfused patients admitted to the intensive care unit during 1992 with ...
Prado-Barreto Valéria M VM Division of Otorhinolaryngology, Federal University of Sergipe, Aracaju, Sergipe, - - 2014
ObjectiveTo evaluate the hearing status of growth hormone (GH)-naive adults with isolated GH deficiency (IGHD) belonging to an extended Brazilian kindred with a homozygous mutation in the GH-releasing hormone receptor gene.Study DesignCross-sectional.SettingDivisions of Endocrinology and Otorhinolaryngology of the Federal University of Sergipe.Subjects and MethodsTwenty-six individuals with IGHD (age, 47.6 ± ...
Aydinonat Denise D Department of Biomedical Sciences, Biochemistry, University of Veterinary Medicine, Vienna, Austria; Department of Integrative Biology and Evolution, Konrad Lorenz Institute of Ethology, University of Veterinary Medicine, Vienna, - - 2014
Telomeres, the caps of eukaryotic chromosomes, control chromosome stability and cellular senescence, but aging and exposure to chronic stress are suspected to cause attrition of telomere length. We investigated the effect of social isolation on telomere length in the highly social and intelligent African Grey parrot (Psittacus erithacus erithacus). Our ...
Anitha Palaniyandi P Sri Ramachandra Medical College and Research Institute, Chennai, Tamil Nadu, - - 2014
Deficiency of vitamin B12 (cobalamin) is a well-known cause of megaloblastic anaemia. It is a reversible cause of bone marrow failure and demyelinating nervous system disorder, hence early detection and prompt treatment of vitamin B12 deficiency is essential. After diagnosing vitamin B12 deficiency, tracking down its root cause is important ...
Harisa Gamaleldin I GI Department of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia; Department of Biochemistry, College of Pharmacy, Al-Azhar University (Boys), Nasr City, Cairo, Egypt. - - 2013
In this study, the protective role of naringin (NAR) against paclitaxel (PTX)-induced erythrocytes aging has been investigated using human erythrocyte as an in vitro model. Erythrocytes were incubated with PTX in the presence and absence of NAR. Incubation of erythrocytes with PTX resulted in increased protein carbonyl content and malondialdehyde ...
Mok Kin Y KY Department of Molecular Neuroscience , UCL Institute of Neurology, Queen Square, London, UK; Reta Lila Weston Institute, UCL Institute of Neurology, London, UK. Electronic address: - - 2013
It is known that Alzheimer's disease (AD) presents at an early age in people with Down syndrome (DS). The trisomy 21 in DS provides an opportunity to study the effect of duplicated genes in AD. APP and BACE2 are 2 genes located in chromosome 21 and related to AD. We ...
Bergfeld Wilma F - - 2013
A young female child aged 7 years presented initially with chronic alopecia areata, which over 2 years progressed to alopecia areata universalis.
Uysal Recep - - 2013
This study examined the mediating effects of Facebook addiction on the relationship between subjective vitality and subjective happiness. 297 university students (157 women, 140 men; M age = 20.1 yr., SD = 1.3) were administered the Facebook Addiction Scale, the Subjective Vitality Scale, and the Subjective Happiness Scale. Hierarchical regression ...
Pelegrín Laura - - 2013
Abstract Purpose: Uveitis is the most common extra-articular manifestation of juvenile idiopathic arthritis (JIA) and is associated with considerable morbidity. The aim of this study was to examine the risk factors associated with uveitis in oligoarticular JIA. Methods: We conducted a chart review of 86 patients with oligoarticular JIA to ...
Liu Yao-Wen - - 2013
A673T, a rare variant in the amyloid-β precursor protein gene, shows a protective potential against Alzheimer's disease (AD) and age-related cognitive decline in an Icelandic population. Although A673T was observed independently in a Finnish population, this variant was absent in 8721 Asian subjects. The conflicting observations suggest that the contribution ...
Joustra S D - - 2013
Context.IGSF1 deficiency was recently discovered as a novel X-linked cause of central hypothyroidism (CeH) and macroorchidism. However, clinical and biochemical data regarding growth, puberty, and metabolic outcome, as well as features of female carriers, are scarce.Objective.To investigate clinical and biochemical characteristics associated with IGSF1 deficiency in both sexes.Methods.All patients (n=42, ...
Weingarz Lea - - 2013
Thrombophilia is a well-established risk factor for a venous thromboembolic event (VTE), and it has been proposed that hereditary thrombophilia may substantially contribute to the development of VTE in young patients. We aimed to analyse the prevalence of thrombophilia with special regard to the age of VTE manifestation. The study ...
Kaukonen Kirsi-Maija - - 2013
Transfusion of red blood cells (RBCs) and, in particular, older RBCs has been associated with increased short-term mortality in critically ill patients. We evaluated the association between age of transfused RBCs and acute kidney injury (AKI), hospital, and 90-day mortality in critically ill patients. We conducted a prospective, observational, predefined ...
Patil Santosh S Dept of Oral medicine and radiology, Jodhpur Dental College, Jodhpur National University, Jodhpur (Raj), - - 2013
Taurodontism affects primarily molars and premolars in both the deciduous and permanent dentition. The aim of the study was to assess the prevalence of taurodontism in the North Indian population. 4143 patients were studied by analyzing the panoramic radiographs for the presence of taurodontism which is defined as the presence ...
Ghashghaeinia Mehrdad - - 2013
Background/Aims: Erythrocytes may enter eryptosis, a suicidal death characterized by cell shrinkage and phosphatidylserine exposure at the erythrocyte outer membrane. Susceptibility to eryptosis is enhanced in aged erythrocytes and stimulated by NFκB-inhibitors Bay 11-7082 and parthenolide. Here we explored whether expression of NFκB and susceptibility to inhibitor-induced eryptosis is sensitive ...
Deckers M M L - - 2013
Reference values of PTH depend on vitamin D status of the reference population. This is often not described in package inserts. The aim of the present study was therefore to calculate assay specific PTH reference levels in EDTA plasma for the Architect (Abbott) in relation to 25-hydroxyvitamin D (25OHD) levels. ...
Franchi Franca - - 2013
Antithrombin (AT), protein C (PC) and protein S (PS) deficiencies are risk factors for venous thromboembolism. Overlapping values between heterozygous carriers and normal individuals often make a correct classification of a deficiency difficult. The aim of this study was to investigate the effect of sex, age, menopause and hormone therapy ...
Audenet François - - 2013
Few risk factors are identified for Renal Cell Carcinoma (RCC). The purpose of this work was to perform a validation study on a population of European background for the most significant variants previously identified in association with RCC risk. We conducted a case-control validation study by recruiting 463 controls and ...
Alsuwadia Abdulkareem O - - 2013
To determine the prevalence of vitamin D deficiency in healthy Saudi adults. A cross-sectional study carried out as part of the screening and early evaluation of kidney disease project. Vitamin D was measured in subjects recruited at 2 screening camps in Riyadh, Saudi Arabia, between March to May 2008. Subjects ...
Machisa Mercilene - - 2013
This study is the second to investigate the association between the use of biomass fuels (BMF) for household cooking and anaemia and stunting in children. Such fuels include coal, charcoal, wood, dung and crop residues. Data from the 2006-2007 Swaziland Demographic and Health Survey (a cross-sectional study design) were analysed. ...
Jamilian A - - 2013
Ankyloglossia or tongue-tie is a congenital condition of newborns when the inferior lingual fraenulum is too short and is attached to the tip of the tongue limiting its movement. The aim of this study was to evaluate the relationship between ankyloglossia classification and tongue mobility. In addition, the prevalence of ...
Krause Matthias - - 2013
Due to inconsistent findings, the influence of vitamin D on postural body sway (PBS) is currently under debate. This study evaluated the impact of vitamin D on PBS with regards to different foot positions and eye opening states in community-dwelling older individuals. In a cross-sectional study, we assessed PBS in ...
Bosco Raquel de Macedo Rde - - 2013
This study evaluated the association between anemia and physical functional capacity in a cross-sectional population-based sample of 709 hospitalized elderly patients aged 60 years and over admitted to the Madre Teresa Hospital, Belo Horizonte, State of Minas Gerais, Brazil. The Mann-Whitney or "t" test, and chi-square or Fisher exact test ...
Li Nan-Nan - - 2013
Alpha-synuclein gene (SNCA) polymorphisms have been associated with Parkinson's disease (PD). A recently published genome-wide association study (GWAS) meta-analysis from the USA and Europe found a strong association between SNCA rs356219 and PD. Considering the population-specific heterogeneity, we investigated the role of SNCA rs356219 as PD susceptibility in a large ...
Vayá Amparo - - 2013
It is not well-established whether the alterations that the hemorheological profile undergoes with aging are an effect of concomitant cardiovascular risk factors or are due to age itself. To clarify this issue, we investigated the effect of age on blood rheology in a population of 927 healthy subjects from eastern ...
Rasmussen Jan - - 2013
BACKGROUND: Primary carnitine deficiency (PCD) is an autosomal recessive disorder of fatty acid oxidation and has been associated to episodes of sudden death in the Faroe Islands. Data are presented from the nationwide population based Faroese screening program to find people with low carnitine levels indicating PCD. METHODS: Whole blood ...
Uluisik D - - 2013
Hematological and biochemical profiles commonly are required in equine medicine. We studied hematological parameters including red blood cells (RBC), white blood cells (WBC), hemoglobin (Hb), hematocrit (PCV), differential leukocyte counts, mean cell volume (MCV), mean corpuscular hemoglobin (MCH), and mean corpuscular hemoglobin concentration (MCHC) in thoroughbred foals at different ages ...
Ceresini Graziano - - 2013
OBJECTIVES: To test the hypothesis that, in older adults, living in a mildly iodine-deficient area, thyroid dysfunction may be associated with mortality independent of potential confounders. DESIGN: Longitudinal. SETTING: Community-based. PARTICIPANTS: Nine hundred fifty-one individuals aged 65 and older. MEASUREMENTS: Plasma thyrotropin, free thyroxine, and free triiodothyronine concentrations and demographic ...
Leibowitz David - - 2013
Although degenerative aortic valve disease is common with increasing age, limited data exist regarding prevalence and prognosis of aortic valve disease among the oldest old. Subjects were recruited from the Jerusalem Longitudinal Cohort Study. Echocardiography was performed at home in 498 randomly selected subjects. Subjects were divided into 3 groups; normal ...
Hasbahceci Mustafa - - 2013
The exact role of boron in humans is not known although its supplementation causes several important metabolic and inflammatory changes. The objective of this study is to evaluate the possibility of an association between blood boron level and obesity in normal, overweight, obese, and morbidly obese subjects. A total number ...
Righetti Aurélie A - - 2013
BACKGROUND: Iron deficiency (ID) is a major cause of anemia, along with other nutritional, parasitic, and genetic factors. Accurate biomarkers are needed to estimate the relative contribution of ID to anemia. Soluble transferrin receptor (sTfR) is thought to be unaffected by inflammation. OBJECTIVES: The objectives were to determine the difference ...
Fedosov Sergey N - - 2013
BACKGROUND: Vitamin B12 deficiency is diagnosed by measurements of total B12, holo-transcobalamin (holoTC), methylmalonic acid (MMA) and total homocysteine (Hcy) in blood. Results of the individual biochemical tests are often contradictory. Here the four markers are combined to achieve a more reliable indication of the B12 status. The results are ...
Akkermans Reinier P - - 2013
To establish which cut-off point for the FEV1/FVC (i.e. fixed 0.70 or Lower Limit of Normal cut-off point) best predicts accelerated lung function decline and exacerbations in middle-aged smokers.We performed secondary analyses on the Lung Health Study dataset. 4,045 smokers aged 35 to 60 years with mild to moderate obstructive ...
Majercik Sarah - - 2013
Red blood cell distribution width (RDW) is a component of the complete blood count (CBC) that is traditionally used to identify iron-deficiency anemia. RDW has been shown to predict mortality in patients with multiple different medical conditions and in general populations. It is unknown whether RDW predicts outcomes in trauma ...
Greenfield Joseph C JC Jr Cardiology Section, Research and Development Service, Durham Veterans Affairs Medical, Center and the Division of Cardiology, Duke University Medical Center, Durham, NC 27710, USA. - - 2013
The prevalence of early repolarization in otherwise normal electrocardiograms as a function of age was evaluated in 2335 Veteran male patients. Thirty-one percent of the patients <35years of age had early repolarization, whereas only 5% of patients >65years of age demonstrated this phenomenon. In addition, only 12% of female patients ...
Santos Betânia R - - 2013
Background/Aims: Vitamin D deficiency has been recognized as a worldwide epidemic affecting several pediatric and adolescent populations. We determined the genotype and haplotype distribution of the rs4588 and rs7041 polymorphisms of the GC gene encoding vitamin D-binding protein (DBP) and investigated the associations between these gene variants and their haplotypes ...
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