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Rahmonov, Ojmahmad
The Błędów Desert, located in the southern part of Poland, is an anthropogenic creature: it has originated in the early Middle Ages and later in the 16th century, owing to deforestation being the result of the develepment of contemporary lead and silver ores mining and metallurgy. A typical aeolian “desert” ...
Concetti Fabio F IRCCS Neuromed, Pozzilli, - - 2014
Recent evidence demonstrated a relevant role of adenosine deaminase (ADA) in replicative senescence of T cells through its capacity to modulate telomerase activity (TA). Herein, we tested the impact of the functional polymorphism ADA rs73598374:G>A (c.22G>A, p.Asp8Asn) on telomere biology, by measuring TA and leukocyte telomere length (LTL) in healthy ...
Pinot Adrien - - 2014
Cyclic rodent population dynamics are subjected to both intrinsic regulatory processes such as density-dependence and extrinsic environmental forcing. Among extrinsic factors, seasonal environmental variation is understood to facilitate cycles. In rodents, these processes have been studied mostly independently and their relative importance for population dynamics is poorly known. We performed ...
Lavagnino Michael M Laboratory for Comparative Orthopaedic Research, College of Veterinary Medicine, Michigan State University, East Lansing, Michigan, - - 2014
BACKGROUND:Tendons are viscoelastic tissues that deform (elongate) in response to cyclic loading. However, the ability of a tendon to recover this elongation is unknown. HYPOTHESIS:Tendon length significantly increases after in vivo or in vitro cyclic loading, and the ability to return to its original length through a cell-mediated contraction mechanism ...
Amberbir Alemayehu A Department of Infectious Disease Epidemiology, London School of Hygiene and Tropical Medicine, UK; Division of Epidemiology and Public Health, University of Nottingham, - - 2014
An inverse relation between Helicobacter pylori infection and allergic disease has been reported by a range of independent epidemiological studies, but evidence from longitudinal studies is scarce. We have investigated the effects of H. pylori infection on the incidence and prevalence of allergic diseases and sensitization in a low-income birth ...
Tay Tunn Ren - - 2013
Adenosine deaminase (ADA) is useful in the diagnosis of tuberculous pleural effusion (TPE). This study aims to determine the factors affecting pleural fluid ADA levels and to establish the optimal ADA levels for diagnosis of TPE for different age groups. This was a retrospective study from January 2007 to October ...
Hsu Chin-Yuan - - 2013
Trophocytes and fat cells of honeybees (Apis mellifera) have been used for cellular senescence studies, but the changes in the expression, concentration, and activity of cellular energy-regulated molecules that occur with aging in worker bees is unknown. In this study, energy-regulated molecules were evaluated in the trophocytes and fat cells ...
Nguyen Thanh H - - 2013
Little information is available concerning the mechanism(s) underlying Takotsubo cardiomyopathy (TTC), other than evidence of associated catecholamine secretion. Given the known effects of catecholamines on endothelial function, we tested the hypothesis that TTC might also be associated with impairment of nitric oxide (NO) signaling. We now report an evaluation of ...
Sokanovic Srdjan J - - 2013
The molecular mechanism of the aging-associated dysfunction of Leydig cells (LCs) is complex and poorly understood. In this study, we analyzed the contribution of nitric oxide (NO) and cGMP signaling to the age-dependent decline in LC function. Significant (>50%) decreases in serum, intratesticular, and LC androgens in aging rats (15-24 ...
Chhabra Preeti - - 2013
Background. Although rotavirus and norovirus cause nearly 40% of severe endemic acute gastroenteritis (AGE) in children <5 years of age in the United States (US), there are limited data on the etiologic role of other enteric viruses in this age group.Methods. We conducted active population-based surveillance in children presenting with AGE to ...
Olson Jasmine M JM Institute of Arctic Biology, University of Alaska Fairbanks, Fairbanks, AK 99775-7000, - - 2013
A₁ adenosine receptor (A₁AR) activation within the central nervous system induces torpor, but in obligate hibernators such as the arctic ground squirrel (AGS; Urocitellus parryii), A₁AR stimulation induces torpor only during the hibernation season, suggesting a seasonal increase in sensitivity to A₁AR signaling. The purpose of this research was to ...
Bergmann S - - 2013
In the previously performed field study from 2007 to 2009, it became evident that foot pad alterations were already commonly found in turkeys at the age of 6 wk. At this early age, 45% of the clinically examined birds were diagnosed with epithelial necrosis. Therefore, it became important to specifically ...
Fathi Farkhondeh - - 2013
The substituted porphyrin 2-cyano-3-(2'-(5',10',15',20-tetraphenyl porphyrinato zinc-(ii))yl) acrylic acid was used to modify nanostructured Ag surfaces. This porphyrin-modified surface exhibits photocurrent when exposed to a light source, which is modulated in the presence of nucleotides. The addition of the nucleotides adenosine-5'-monophosphate (AMP), guanosine-5'-monophosphate (GMP) and cytidine-5'-monophosphate (CMP) causes partial quenching of ...
Donohue Kathleen M KM Division of Pulmonary, Allergy and Critical Care, Columbia University School of Physicians and Surgeons, New York, NY, USA. - - 2013
Bisphenol A (BPA) is used widely to manufacture food container linings. Mouse models suggest exposure to BPA might increase allergic inflammation. We hypothesized that BPA exposure, as assessed based on urinary BPA concentrations, would be associated with increased odds of wheeze and asthma and increased fraction of exhaled nitric oxide ...
Kudô K - - 2013
Cyclical oligogyny is considered to be the mechanism that is most likely to be responsible for stabilizing cooperation in polygynous, epiponine wasps, in which single-queen colonies produce new queens and multiple-queen colonies produce males. In contrast with the number of studies on relatedness among adult females, we know little about ...
Chen Wei-Hong - - 2012
Human disc degeneration initiated by aging in the central nucleus pulposus (hNP) is an irreversible process and the recovery has become seriously emerging. In this study, the related mechanisms of calcitonin on the regeneration of hNP and the effects of calcitonin on the age-related alterations were examined. The harvested hNP ...
Wixner J - - 2012
Gastrointestinal (GI) complications are common in hereditary transthyretin amyloidosis and an autonomic dysfunction has been considered to explain these symptoms. The aim of this study was to investigate the impact of autonomic neuropathy on gastric emptying in hereditary transthyretin amyloidosis and to relate these findings to nutritional status, GI symptoms, ...
Butler Andrew A AA Department of Metabolism and Aging, The Scripps Research Institute, 130 Scripps Way, Jupiter, Florida 33458, USA. - - 2012
Mouse studies suggest that adropin, a peptide hormone, is required for metabolic homeostasis and prevention of obesity-associated insulin resistance. Whether obesity and insulin resistance are associated with low plasma adropin levels in humans is not known. Our objective was to investigate the hypothesis that obesity and indicators of insulin resistance ...
Padmanabhan V - - 2012
Prenatal testosterone (T) excess leads to reproductive dysfunctions in sheep with obesity exaggerating such defects. Developmental studies found ovarian reserve is similar in control and prenatal T sheep at fetal day 140, with prenatal T females showing increased follicular recruitment and persistence at 10 months of age (postpubertal). This study ...
Camilleri M M Clinical Enteric Neuroscience Translational and Epidemiological Research (CENTER), College of Medicine, Mayo Clinic, Rochester, MN 55905, USA. - - 2012
Gastric emptying (GE) is measured in pharmacodynamic and diagnostic studies. Our aim was to assess inter- and intra-subject coefficients of variation (COV) of scintigraphic GE measurements in healthy subjects, and associations of GE with gender and body mass index (BMI). Data from participants with scintigraphic measurements of gastric emptying of ...
King Wendy C WC Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA. - - 2012
Anecdotal reports suggest bariatric surgery may increase the risk of alcohol use disorder (AUD), but prospective data are lacking. To determine the prevalence of preoperative and postoperative AUD, and independent predictors of postoperative AUD. A prospective cohort study (Longitudinal Assessment of Bariatric Surgery-2) of adults who underwent bariatric surgery at ...
Felley Christian C Service of Gastroenterology, University Hospital, 1000 Lausanne, - - 2012
To assess the role of Helicobacter pylori (H. pylori), gastroesophageal reflux disease (GERD), age, smoking and body weight on the development of intestinal metaplasia of the gastric cardia (IMC). Two hundred and seventeen patients scheduled for esophagogastroduodenoscopy were enrolled in this study. Endoscopic biopsies from the esophagus, gastroesophageal junction and ...
Di Ciaula Agostino - - 2012
Background:  Impaired gallbladder and gastric motility have been associated with obesity in adults. The timing of appearance of this dysfunction, however, is unclear. Methods:  Lean and obese subjects from 3 different age groups were studied noninvasively: 50 newborns (1-12 months old, 6 obese), 18 preadolescents (7-8 years old, 7 obese), ...
Nylund K - - 2012
Purpose: To describe the gastrointestinal (GI) wall thickness and the thickness of individual wall layers in healthy subjects using ultrasound and to determine whether demographic factors, the ultrasound transducer frequency, or a fasting state influences these measurements. Materials and Methods: After overnight fasting, the GI wall thickness and wall layers ...
Silva Gisela M M - - 2012
Recently, surgical intervention has gained increasing support in adolescents with extreme obesity. This study summarizes the analysis into the effect of laparoscopic adjustable gastric bands (LAGB) on cardiovascular risk factors in 14 extremely obese Portuguese adolescent patients. Data collected both pre- and postoperatively included age, gender, body mass index (BMI), ...
Buchholz Vered - - 2012
BACKGROUND: Obesity is associated with a poor anesthetic risk, in part because of the greater aspiration rates. A greater gastric residue and lower stomach pH have been implicated. The relationship of obesity to gastric emptying is ill-defined. with contradicting reports stating shorter, similar, and longer times compared with nonobese subjects. ...
Jing Jing-Jing JJ Tumor Etiology and Screening Department of Cancer Institute and General Surgery, The First Affiliated Hospital of China Medical University, Key Laboratory of Cancer Control in Liaoning Province, Shenyang 110001, Liaoning Province, - - 2012
To investigate the incidence and mortality of gastric cancer (GC) in Zhuanghe region, northeast China and the influencing factors for their changing trends. All new cancer cases and deaths registered from 2005 to 2010 in Zhuanghe County were reviewed. The annual GC cases, constituent ratio, crude rates, age-standardized rates, their ...
Chen Yu - - 2012
Few studies have evaluated the potential influence of Helicobacter pylori on biomarkers for diabetes. We conducted cross-sectional analyses using data from 7417 participants in the National Health and Nutrition Examination Survey (NHANES) III (aged ≥18 years) and 6072 participants in NHANES 1999-2000 (aged ≥3 years) to assess the association between ...
Tamnes Christian K - - 2012
Cognitive development is known to involve improvements in accuracy, capacity, and processing speed. Less is known about the role of performance consistency, and there has been virtually no empirical examination of the neural underpinnings of within-person variability in development. In a sample of 92 healthy children and adolescents aged 8-19 ...
van Leeuwen Fred - - 2012
Comment on: De Vos D, et al. EMBO Rep 2011; 12:956-62. doi:10.1038/embor.2011.131.
Sarma Nilendu - - 2012
A female child developed multiple, progressive, therapy-resistant, painful large ulcers, vesicles, and pustules since her 4 months of age. The ulcers were large, some even measured more than 8 cm; most had violaceous undermined margin with surrounding erythematous halo, raw and crusted surface and were distributed extensively over scalp, face, ...
Taddei Francesco - - 2011
PURPOSE: Open-skill sports requires high levels of visual attention, fast and flexible decision making and action execution. We evaluated whether these sports may counteract the well known age-related declines in executive processing. METHODS: Young and middle-age fencers and non-athletes were studied. Participants (N=40) performed visual motor tasks while reaction times ...
Rahman Irfan - - 2012
Chronic inflammation and cellular senescence are intertwined in the pathogenesis of premature aging, which is considered as an important contributing factor in driving chronic obstructive pulmonary disease (COPD). Sirtuin1 (SIRT1), a nicotinamide adenine dinucleotide (NAD(+))-dependent protein/histone deacetylase, regulates inflammation, senescence/aging, stress resistance, and deoxyribonucleic acid (DNA) damage repair via deacetylating ...
Zeng Yan Y Department of Psychiatry and Biobehavioral Sciences, Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, California 90024, - - 2011
Aging-related cognitive declines are well documented in humans and animal models. Yet the synaptic and molecular mechanisms responsible for cognitive aging are not well understood. Here we demonstrated age-dependent deficits in long-term synaptic plasticity and loss of dendritic spines in the hippocampus of aged Fisher 344 rats, which were closely ...
Murphy Hayley Weston - - 2011
A total of 163 echocardiographic studies on western lowland gorillas (Gorilla gorilla gorilla) were submitted for evaluation; 140 from 99 animals were suitable for analysis. Of these, 81 studies (42 studies from 35 males ranging in age from 11-41+ yr and 39 studies from 31 females ranging in age from ...
Cho Sung-Il - - 2011
Gastric cancer has a high incidence and mortality rate in Korea. Despite a growing older population and an increase in the number of older patients with gastric cancer, the older patients are not willing to undergo surgery due to their operative risks. Hence, to determine the clinical characteristics and outcomes ...
Gao Fengxiang - - 2012
The performance of rapid influenza diagnostic tests (RIDTs) in detecting influenza A(H1N1) 2009 has varied widely. Evaluations of RIDTs among infected individuals across all age groups have not been described in depth. Determine RIDT clinical sensitivity in comparison with influenza detection using real-time RT-PCR among patients infected with influenza A(H1N1) ...
Park Lara K - - 2012
Nutritional epigenetics has emerged as a novel mechanism underlying gene-diet interactions, further elucidating the modulatory role of nutrition in aging and age-related disease development. Epigenetics is defined as a heritable modification to the DNA that regulates chromosome architecture and modulates gene expression without changes in the underlying bp sequence, ultimately ...
Kuwamura Tetsuo - - 2011
Sex change, either protogyny (female to male) or protandry (male to female), is well known among fishes, but evidence of bidirectional sex change or reversed sex change in natural populations is still very limited. This is the first report on female removal experiments for polygnous and protogynous fish species to ...
Siviero-Miachon Adriana Aparecida - - 2011
To analyze traits of metabolic syndrome (MetS) in medulloblastoma survivors. Sixteen childhood medulloblastoma survivors aged 18.0 (4.4) years, with history of craniospinal radiation therapy (RT) were compared with nine control subjects matched by age, gender, and body mass index, according to fat distribution, metabolic and cardiovascular variables. Medulloblastoma patients showed ...
Arita Adriana - - 2012
Occupational exposure to nickel (Ni) is associated with an increased risk for lung and nasal cancers. Ni compounds exhibit weak mutagenic activity, cause gene amplification, and disrupt cellular epigenetic homeostasis. However, the Ni-induced changes in global histone modification levels have only been tested in vitro. This study was conducted in ...
Behm David G - - 2011
Middle-aged individuals may not respond in a similar manner as younger individuals. The study's objective was to examine the effect of static (SS) and dynamic stretching (DS) in young and middle-aged men on subsequent performance. Ten young (22 ± 1.4 years) and 8 middle-aged men (46.3 ± 6.5 years) participated in 3 conditions consisting ...
Deibert Peter - - 2011
Abstract Objective.?To determine changes in body composition, physical performance, metabolic and hormonal parameters induced by lifestyle counselling, resistance training and resistance training with soy protein based supplemention in middle aged males. Design.?Randomised controlled study consisting of resistance training without (RT-G) or with (RTS-G) a soy protein based supplement and a ...
Maures Travis J - - 2011
Aging is accompanied by alterations in epigenetic marks that control chromatin states, including histone acetylation and methylation. Enzymes that reversibly affect histone marks associated with active chromatin have recently been found to regulate aging in Caenorhabditis elegans. However, relatively little is known about the importance for aging of histone marks ...
Klayton Tracy L - - 2011
It is widely believed that younger prostate cancer patients are at greater risk of recurrence following radiotherapy (RT). From 1992 to 2007, 2168 (395 age ≤ 60) men received conformal RT alone for prostate cancer at our institution (median dose=76 Gy, range: 72-80). Multivariable analysis (MVA) was used to identify ...
Kremen William S - - 2011
Studies comparing young and older adults suggest a deficit in processing context information as a key mechanism underlying cognitive aging. However, the genetic architecture of context processing has not been examined. Consistent with previous results, we found evidence of functionally dissociable components of context processing accuracy in 1127 late middle-aged ...
Lunyak Victoria V - - 2011
Defining the molecular events that precipitate multisystem decline is an important component of aging research. In this issue, Jin et al. (2011) show that increased expression of the histone demethylase, utx-1, causes genome-wide decreases in histone H3K27 trimethylation, which includes the insulin/IGF-1 signaling (IIS) pathway that promotes aging.
Akimkin V - - 2011
Turkey rotaviruses are one of the major pathogens responsible for the poult enteritis syndrome (PES). In this study a one step real-time reverse transcription polymerase chain reaction (RT-qPCR) assay targeting the rotaviral non-structural protein 4 (NSP4) was developed. The NSP4 is a highly conserved gene inside the turkey rotavirus genome ...
Pilz Karin S - - 2011
Object recognition is an important visual process. We are not only required to recognize objects across a variety of lighting conditions and variations in size, but also across changes in viewpoint. It has been shown that reaction times in object matching increase as a function of increasing angular disparity between ...
Fernández Agustín F - - 2011
The physiological effects of the dietary polyphenol resveratrol are being extensively studied. Resveratrol has been proposed to promote healthy aging and to increase lifespan primarily through the activation of the class III histone deacetylases (sirtuins). Although its positive effects are evident in yeast and mice they still have to be ...
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