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Abrao F C FC Department of Thoracic Surgery, Hospital Santa Marcelina, São Paulo, - - 2014
1) To determine factors affecting adenosine deaminase (ADA) levels in pleural fluid (PF), and 2) to establish the optimal ADA cut-off level for a Brazilian population. ADA levels in PF of 309 patients were analysed to investigate pleural effusion. All patients were evaluated for age, sex and presence of tuberculosis ...
Afrane Yaw A - - 2014
In African highland areas where endemicity of malaria varies greatly according to altitude and topography, parasitaemia accompanied by fever may not be sufficient to define an episode of clinical malaria in endemic areas. To evaluate the effectiveness of malaria interventions, age-specific case definitions of clinical malaria needs to be determined. ...
Jackson B T BT Department of Evolution, Ecology and Organismal Biology, Ohio State University, Columbus, OH, - - 2014
A large-scale mesocosm was constructed and tested for its effectiveness for use in experiments on behaviour, reproduction and adult survivorship in the Afrotropical malaria vector Anopheles gambiae s.s. Giles (Diptera: Culicidae) in temperate climates. The large space (82.69 m(3) ) allowed for semi-natural experiments that increased demand on a mosquito's ...
von Fricken Michael E - - 2014
Malaria transmission continues to occur in Haiti, with 25,423 confirmed cases of Plasmodium falciparum and 161,236 suspected infections reported in 2012. At low prevalence levels, passive surveillance measures, which rely primarily on reports from health systems, becomes less appropriate for capturing annual malaria incidence. To improve understanding of malaria transmission ...
Ndong Ignatius C - - 2014
Malaria is the leading cause of death worldwide. It is urgent to assess the impact of interventions and scaled-up control efforts. Despite reported reduction in malaria prevalence in Africa, the trends in Cameroon are not yet fully understood. The aim of this study was to investigate the trends in malaria ...
Kuan M-M MM *Centers for Disease Control, Taipei, - - 2014
Taiwan's criterion for admissions of new immigrants is a normal chest X-ray (CXR). Subsequent tuberculosis (TB) screening for new foreign spouses is mandatory before acquiring citizenship. To estimate the TB burden among new-entry foreign spouses and their close contacts. Of 768 new foreign spouses with TB, of whom 98.6% were ...
Minois Nadège N School of Biology, University of St Andrews, St Andrews, - - 2014
Background: Spermidine, a naturally occurring polyamine, has recently emerged as exhibiting anti-aging properties. Its supplementation increases lifespan and resistance to stress, and decreases the occurrence of age-related pathology and loss of locomotor ability. Its mechanisms of action are just beginning to be understood. Objectives: An up-to-date overview of the so ...
Hurt Ryan T RT 1Division of General Internal Medicine, Mayo Clinic , Rochester, MN , - - 2014
ABSTRACT Background: Visceral adiposity has been linked to higher rates of cardiometabolic risk than other types of adiposity. Waist circumference (WC) is the best anthropomorphic surrogate of visceral adiposity. Reductions in central adiposity may decrease cardiovascular risk. Animal studies have demonstrated that L-arginine reduces visceral adiposity and fat mass. The ...
Kibe Ryoko R 1] Benno Laboratory, RIKEN Innovation center, Wako, Saitama 351-0198, Japan - - 2014
Prevention of quality of life (QOL) deterioration is associated with the inhibition of geriatric diseases and the regulation of brain function. However, no substance is known that prevents the aging of both body and brain. It is known that polyamine concentrations in somatic tissues (including the brain) decrease with increasing ...
Desai Meghna M Kenya Medical Research Institute/Centers for Disease Control and Prevention (KEMRI/CDC) Research and Public Health Collaboration, Kisumu, Kenya; Division of Parasitic Diseases and Malaria (DPDM), Center for Global Health (CGH), CDC, Atlanta, Georgia, United States of - - 2014
Recent global malaria burden modeling efforts have produced significantly different estimates, particularly in adult malaria mortality. To measure malaria control progress, accurate malaria burden estimates across age groups are necessary. We determined age-specific malaria mortality rates in western Kenya to compare with recent global estimates. We collected data from 148,000 ...
Jung Christian - - 2013
BACKGROUND AND AIMS: Overweight and the metabolic syndrome have become major problems, especially in children and adolescents. Obesity at a young age increases the risk for cardiovascular diseases and diabetes mellitus later in life. An early event in the development of cardiovascular disease is endothelial dysfunction which is found in ...
Gupta Neeraj - - 2012
A growing body of evidence suggests the involvement of L-arginine and its metabolites in the aging and neurodegenerative processes. The present study assessed behavioural performance in 4 (young), 12 (middle-aged) and 24 (aged) months old male Sprague-Dawley rats, and investigated age-related changes in the activity of two key arginine metabolic ...
Pucciarelli Stefania - - 2012
Polyamines (putrescine, spermidine and spermine) are a family of molecules deriving from ornithine, through a decarboxylation process. They are essential for cell growth and proliferation, stabilization of negative charges of DNA, RNA transcription, translation and apoptosis. Recently, it has been demonstrated that exogenously administered spermidine promotes longevity in yeasts, flies, ...
Zhang Yan - - 2012
OBJECTIVES: This report investigates the etiology of recurrent episodic elevations in plasma ammonia in an adolescent male with arginase deficiency as there were concerns regarding pre-analytical and analytical perturbations of ammonia measurements. There were repeated discrepancies between the magnitude of his ammonia levels and the severity of his clinical signs ...
Benjaminov Fabiana - - 2012
BACKGROUND AND AIM: Increased common bile duct (CBD) diameter has been attributed to aging and previous cholecystectomy. These relationships are, however, controversial and based mainly on old studies and methodologies. Our objective is to evaluate the relationship between age, cholecystectomy, and other clinical factors and CBD diameter, as measured by ...
Kobayashi Yasuhisa - - 2012
The gobiid fish Trimma okinawae changes its sex bi-directionally according to its social status. Morphological changes in the urinogenital papillae (UGP) of this fish have been reported during sex change. However, there have been no detailed observations of such changes. Here, we histologically examined the UGP structure of male- and ...
Rosewich Martin - - 2011
BACKGROUND: Smoking is the single most important risk factor for the development of chronic obstructive pulmonary disease, and more than 80% of adult smokers started smoking before the age of 20. The aim of our study was to evaluate the early impact of smoking on lung function, health, and well-being ...
Gasparoto T H - - 2011
We have identified impaired neutrophils in elderly individuals which could be involved with Candida-related denture stomatitis (DS), an oral infection predominantly caused by Candida albicans, affecting especially elderly individuals using dental prosthesis. However, specific mechanisms performed by neutrophil contributing to the susceptibility of the elderly to DS are not fully ...
Risch C - - 2011
Introduction:  After measurement of the mean volumes of leukocyte subpopulations as well as the distribution widths (DW) of these volumes has become available, we investigated whether such morphometric leukocyte parameters are associated with a commonly used marker of cobalamin deficiency, i.e., holotranscobalamin (HoloTC). Further, we determined reference intervals for these ...
Hoffmann Jedrzej - - 2011
Atherosclerosis is an age-related systemic disease characterized by systemic oxidative stress and low grade chronic inflammation. Various types of leukocytes play an important role within this process. Telomeres, the ends of chromosomes, shorten during each and every cell division and have therefore been regarded as a cellular clock. Telomere dysfunction ...
Silverberg Jonathan I - - 2011
To cite this article: Silverberg JI, Kleiman E, Silverberg NB, Durkin HG, Joks R, Smith-Norowitz TA. Chickenpox in childhood is associated with decreased atopic disorders, IgE, allergic sensitization, and leukocyte subsets. Pediatr Allergy Immunol 2011; Doi: 10.1111/j.1399-3038.2011.01224.x. ABSTRACT: Background:  Wild-type varicella zoster infection (WTVZV) up to 8 yr of age has ...
Wohlfeil Martin - - 2011
The inflammatory mediators, serum elastase and C-reactive protein (CRP), are associated with an increased risk for coronary heart disease. Thus, the aim of this study is to compare systemic inflammatory mediators in periodontally healthy controls (C), patients with untreated aggressive (AgP) and chronic (ChP) periodontitis. C [periodontal pocket probing depth ...
Buchmann Arlette F - - 2011
There is converging evidence suggesting a particular susceptibility to the addictive properties of nicotine among adolescents. The aim of the current study was to prospectively ascertain the relationship between age at first cigarette and initial smoking experiences, and to examine the combined effects of these characteristics of adolescent smoking behavior ...
Elabiad Mohamad T - - 2011
: Evaluate the hypothesis that the same pepsinogen C molecule produced in the stomach is also produced by the lung. : Pulmonary and gastric tissues collected postmortem were immunohistochemically stained for pepsinogen C and pepsinogen A. : Sixteen patients with diverse causes of death were evaluated. Gestational age at birth ...
Hoffmann Jedrzej - - 2011
Atherosclerosis is an age-related systemic disease characterized by systemic oxidative stress and low grade chronic inflammation. Various types of leukocytes play an important role within this process. Telomeres, the ends of chromosomes, shorten during each and every cell division and have therefore been regarded as a cellular clock. Telomere dysfunction ...
Trachsel Daniel - - 2011
BackgroundSevere bronchopulmonary dysplasia (BPD) might be associated with an accelerated age-related decline of lung function.Methods14 individuals were studied longitudinally at 15±4, 18±3 and 38±3.2 years. Information on personal history was completed, and lung function testing and skin prick testing were performed. Longitudinal data were compared intra-individually and with matched controls ...
Noborisaka Yuka - - 2012
To clarify the renal effects of cigarette smoking in a middle-aged occupational population because the effects have previously been demonstrated mainly in community populations that included many elderly people who are thought to be vulnerable to such effects. In 990 middle-aged men recruited from a chemical plant, proteinuria was measured ...
Kerr David C R DC Oregon State University, Department of Psychology, Corvallis, OR 97331, USA. - - 2011
To describe the rate and timing of smoking onset, prolonged abstinence (≥1 year) and relapses from ages 18 to 32 years in initially smoking and non-smoking men. A 23-year longitudinal study. Untreated community sample. A total of 154 American boys were recruited at age 10 years to a larger study ...
Ben Saad H H Service de physiologie et des explorations fonctionnelles, EPS Farhat Hached, Sousse, Tunisia. - - 2011
Studies of the spirometric profiles of narghile smokers are few, have some methodological limits (i.e. small sample size), and present contradictory conclusions. (i) To determine the percentage of narghile smokers with obstructive ventilatory defect (OVD) and/or restrictive ventilatory defect (RVD) or static hyperinflation (SHI); (ii) to compare the chronological and ...
Redente Elizabeth F EF Program in Cell Biology, Department of Pediatrics, National Jewish Health, Denver, CO 80206, - - 2011
Fibrotic interstitial pneumonias are more prevalent in males of advancing age, although little is known about the underlying mechanisms. To evaluate the contributions of age and sex to the development of pulmonary fibrosis, we intratracheally instilled young (8-12 wk) and aged (52-54 wk) male and female mice with bleomycin and ...
Gläser S - - 2012
Although several levels of evidence have suggested an association between systemic inflammation and spirometric lung volumes, data addressing the potential interrelationship between airflow limitation and inflammatory markers are sparse and remain controversial. Potential associations between high-sensitivity C-reactive protein (hsCRP), fibrinogen and lung function were investigated in 1,466 individuals aged 25-85 ...
Carroll Douglas - - 2011
Objective Reduced lung function has been linked to poorer cognitive ability later in life. In the present study, the authors examined the converse: whether there was a prospective association between cognitive ability in early adulthood and lung function in middle age. Methods Participants were 4256 male Vietnam-era US veterans. Cognitive ...
Strandberg Timo E - - 2011
BACKGROUND: Leukocyte telomere length has been taken as a measure of biological age but several inconsistencies exist. METHODS: We investigated associations between leukocyte telomere length in old age, midlife risk factors, and mortality. The Helsinki Businessmen Study (a cohort of mainly business executives, born 1919-1934) had baseline assessments of cardiovascular ...
Moreira André - - 2011
We postulated that high level swimming can promote airway inflammation and thus asthma by enhancing local vascular permeability. We aimed to test this hypothesis by a cross-sectional study comparing swimmers (n = 13, 17 ± 3 years, competing 7 ± 4 years, training 18±3 h per week), asthmatic-swimmers (n = 6, 17 ± 2 years, competing 8 ± 3 years, training 16 ± 4 h per ...
Scherr Johannes - - 2011
PURPOSE: Strenuous exercise significantly increases the incidence of upper respiratory tract illness (URTI) caused by transient immune dysfunction. Naturally occurring polyphenolic compounds present in food such as non-alcoholic beer (NAB) have strong anti-oxidant, antipathogenic, and anti-inflammatory properties.The objective of this study was to determine whether ingestion of non-alcoholic beer polyphenols ...
Starr John M JM Centre for Cognitive Ageing and Cognitive Epidemiology, Geriatric Medicine, University of Edinburgh, Royal Victoria Hospital, Edinburgh, Scotland, UK. - - 2011
Haematological abnormalities are important to detect. In older adults there are few data that inform about normal ranges and the change in blood cell counts with ageing. These few data indicate that sex differences in blood cell counts persist beyond 70 years. To determine normal ranges for blood cell counts ...
Chambers James K - - 2011
Senile plaques (SP) are characteristic histopathological manifestations of Alzheimer's disease (AD), but are also found in normal aging (NA). Recent studies have demonstrated that beta amyloid (Aβ) proteins that have been truncated at the N-terminal position 3 (AβpN3) are the predominant component of SP in AD, but not in NA. ...
Pignatti Patrizia - - 2011
Abstract Background: Although an influence of advancing age on lung cellularity in healthy subjects has already been described, induced sputum reference values for cell counts in older healthy adults are not available. The aim of the present study was to evaluate the influence of age on the variation of sputum ...
Campuzano Oscar - - 2011
Brain aging is associated to several morphological and functional alterations that influence the evolution and outcome of CNS damage. Acute brain injury such as an excitotoxic insult induces initial tissue damage followed by associated inflammation and oxidative stress, partly attributed to neutrophil recruitment and the expression of oxidative enzymes such ...
Kim Sung Hun - - 2011
Previous reports have shown that cigarette smoking is associated with white matter hyperintensities (WMHs). However, it remains unclear whether this is true for all ages. We investigated the association between cigarette smoking, WMHs, and age. We retrospectively reviewed charts from 595 patients, who presented as outpatients from January 2007 to ...
Cobo Teresa - - 2011
OBJECTIVE: We sought to evaluate gestational age, cervical length, amniotic fluid interleukin (IL)-6, and selected proteomic biomarkers as independent predictors of adverse outcome in preterm premature rupture of membranes (PPROM). STUDY DESIGN: This was a prospective cohort study of 65 consecutive women with PPROM (20.0-34.6 weeks). Gestational age, cervical length, ...
Monteiro Cassandra M - - 2011
Forty-seven specimens of Neotropical cormorants, Phalacrocorax brasilianus, from Lago Guaíba, Guaíba, State of Rio Grande do Sul, Brazil (30° 00' S, 51°15' W), were examined for helminth parasites between 1999 and 2003. Twenty species of helminth parasites were found: ten digeneans: Austrodiplostomum mordax, Austrodiplostomum compactum, Clinostomum sp., Drepanocephalus olivaceus, Drepanocephalus ...
Diamanka Arfang - - 2011
Lamellodiscus dentexi Aljoshkina, 1984, a gill parasite of Dentex macrophthalmus (Bloch), is redescribed based on new material from the northwest coast of Africa (Senegal and Morocco). Three new species of Lamellodiscus Johnston et Tiegs, 1922 from D. macrophthalmus are described, Lamellodiscus toguebayei sp. n., L. vicinus sp. n., and L. ...
Labruna Marcelo B - - 2011
The present study evaluated the reproductive compatibility of the crosses between adult ticks of the following three geographically different populations of Amblyomma cajennense: State of São Paulo (SP), southeastern Brazil; State of Rondônia (RO), northern Brazil; and Colombia (CO). In addition, crosses between A. cajennense ticks from Argentina (AR) and ...
Martin A - - 2011
Emotional sweating and malodour production represent a relevant challenge to today's antiperspirant (AP) and deodorant products as stress in everyday life increases continuously. The aim of this study was to investigate stress-induced sweating in teenagers who are known to experience various stressful situations, e.g. exams at school or job interviews. ...
Oskis Andrea - - 2011
Attachment style has been linked with basal cortisol secretion in healthy adult women. We investigated whether dysregulation in basal cortisol secretion may be evident in younger healthy females. Sixty healthy females aged 9-18 years (mean 14.16, SD ± 2.63 years) participated in the Attachment Style Interview (ASI). Eight saliva samples, ...
Lin Chin-An - - 2011
Surface plasmon (SP) mediated emission from ZnO nanorod arrays (NRAs)/Ag/Si structures has been investigated. The ratio of visible emission to UV emission can be increased by over 30 times via coupling with SP without deterioration of the crystal quality. The fact that the effect of SP crucially depends on the ...
Mekrungrongwong Sunsanee - - 2011
WHO estimates that 8.4 million deaths will be counted a year due to tobacco by 2020, and 70% of those deaths will occur in developing countries. Examination of the magnitude of socioeconomic differences in smoking between different age groups reveals specific groups anti-smoking programs should target on. This study aimed ...
Teichmann J - - 2011
Background. Previous research on the combined association of 25-hydroxyvitamin D [25(OH)D] and exocrine pancreas insufficiency may have been limited by restricted age variability and a lack of representation of both body weight and body mass index. There are still too few conclusive reports about conspicuous vitamin D metabolism according to ...
Wallin-Bengtsson Viveca - - 2011
The aim of this study was to investigate if periodontal parameters and elastase in gingival crevicular fluid (GCF) are different in alpha-1-antitrypsin deficient (AATD) subjects compared to subjects with normal AAT level. Thirty subjects were included, 20 of whom with severe AATD, phenotype PiZZ. Ten AATD subjects suffered from chronic ...
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