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Abdulrahim Sawsan S Department of Health Promotion and Community Health, Faculty of Health Sciences, American University of Beirut, Beirut, - - 2014
This spotlight offers a unique window into factors affecting aging in Lebanon. As a bridge between east and west, both geographically and culturally, Lebanon has the fastest growing older adult population in the Arab region, but few societal resources to address its needs. In a country with a history of ...
Meadows Kristy L KL Tufts University Cummings School of Veterinary Medicine, 200 Westboro Rd., Grafton, MA 01536. Electronic address: - - 2014
Relaxin is an essential pregnancy-related hormone with broad peripheral effects mediated by activation of relaxin-like family peptide 1 receptors (RXFP1). More recent studies suggest an additional role for relaxin as a neuropeptide, with RXFP1 receptors expressed in numerous brain regions. Neurons in an area of the brainstem known as the ...
Saksens Nicole N Ophthalmology, Radboud University Medical Center, philips van Leydenlaan 15, Nijmegen, 6525 EX, - - 2014
Purpose: To describe the differences and similarities in clinical characteristics and phenotype of familial and sporadic patients with age-related macular degeneration (AMD). Methods: We evaluated data of 1828 AMD patients and 1715 controls enrolled in the European Genetic Database. All subjects underwent ophthalmologic examination, including visual acuity testing and fundus ...
Sansbury Francis H FH Peninsula Clinical Genetics Service, Royal Devon & Exeter NHS Foundation Trust, Royal Devon & Exeter Hospital (Heavitree), Exeter, UK University of Exeter Medical School, University of Exeter, Exeter, UK Bristol Clinical Genetics Service, University Hospitals Bristol NHS Foundation Trust, Clinical Genetics, St. Michael's Hospital, Bristol, - - 2014
Inherited abnormalities of complement are found in ∼60% of patients with atypical haemolytic uraemic syndrome (aHUS). Such abnormalities are not fully penetrant. In this study, we have estimated the penetrance of the disease in three families with a CFH mutation (c.3643C>G; p. Arg1215Gly) in whom a common lineage is probable. ...
McGue Matt M Department of Psychology, University of Minnesota, 75 East River Rd., Minneapolis, MN, 55455, USA, - - 2014
Parent-offspring resemblance for drinking was investigated in a sample of 409 adopted and 208 non-adopted families participating in the Sibling Interaction and Behavior Study. Drinking data was available for 1,229 offspring, assessed longitudinally up to three times in the age range from 10 to 28 years. A single drinking index was ...
Sakamoto Taro T School of Pharmacy, Kitasato University, 5-9-1 Shirokane, Minato-ku, Tokyo, 108-8641, - - 2014
The glutathione peroxidase (GPx) family is a major antioxidant enzyme family that catalyzes the reduction of a variety of hydroperoxides. GPxs are divided into selenium- and nonselenium-containing GPxs. Because of their efficient antioxidant activity, which depends on the presence of the amino acid residue selenocysteine, selenium-containing GPxs have been the ...
Hartman Sarah S University of - - 2014
Manuck, Craig, Flory, Halder, and Ferrell (2011) reported that a theoretically anticipated effect of family rearing on girls' menarcheal age was genetically moderated by two single nucleotide polymorphisms (SNPs) of the estrogen receptor-α gene. We sought to replicate and extend these findings, studying 210 White females followed from birth. The ...
Coile A M AM Department of Biological Sciences, Arkansas State University, PO Box 599, State University, Jonesboro, AR, 72467, - - 2014
The reproductive success of female Gnathia marleyi (Crustacea: Isopoda) was examined among individuals from eight species belonging to five families of common Caribbean reef fishes of St. John, US Virgin Islands that differ in susceptibility to G. marleyi infestation. Fish were placed in cages during times of peak gnathiid activity. ...
Tomicek Nanette J NJ Intercollege Program in Physiology, The Pennsylvania State University, University Park, Pennsylvania, - - 2014
The aged, post-menopausal female heart is characterized by reduced ischemic tolerance, and few therapies currently exist to limit ischemic damage. Adiponectin (APN), a cytokine produced in adipose tissue, limits infarct size and improves functional recovery after ischemia/reperfusion injury in adult hearts. The aim of the present study was to extend ...
Ambe Kimiharu K Division of Oral Histology, Department of Morphological Biology, Ohu University School of Dentistry, Japan. Electronic address: - - 2014
Enzymes synthesizing reactive oxygen (Nox family) have recently been identified. Elucidation of the production mechanism has been initiated, and the involvement of reactive oxygen in metabolism, intracellular transport, signal transmission and apoptosis has been reported. We immunohistochemically investigated expression and localization of the Nox family in endochondral ossification using a ...
Lichenstein Sarah D SD Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA, 15213, - - 2014
Abstract Aim: Familial loading for alcohol dependence (AD) and variation in genes reported to be associated with AD or BMI were tested in a longitudinal study. Growth curve analyses of BMI data collected at approximately yearly intervals and obesity status (BMI > 30) were examined. High-risk males were found to ...
Manning Wendy D WD Department of Sociology, Bowling Green State University, Bowling Green, OH - - 2014
The landscape of union formation has been shifting; Americans are now marrying at the highest ages on record and the majority of young adults have cohabited. Yet little attention has been paid to the timing of cohabitation relative to marriage. Using the National Survey of Families and Households and 4 ...
Liu Li L Department of Epidemiology and Biostatistics and Guangdong Key Lab of Molecular Epidemiology, School of Public Health, Guangdong Pharmaceutical University, Guangzhou, - - 2014
There was lack of evidence for familial aggregation in onset age of hepatocellular carcinoma (HCC) in Chinese population. We conducted a population-based case-control family study to examine familial correlation of age of HCC onset in Taixing, China. A total of 202 cases and 202 matched controls as well as their ...
García-R Juan C JC Phoenix Lab, Ecology Group, Institute of Agriculture and Environment, Massey University, Palmerston North, New - - 2014
Central to our understanding of the timing of bird evolution is debate about an apparent conflict between fossil and molecular data. A deep age for higher level taxa within Neoaves is evident from molecular analyses but much remains to be learned about the age of diversification in modern bird families ...
Santos Daniel M V DM Centre of Research, Education, Innovation and Intervention in Sport, Faculty of Sports, University of Porto, Porto, - - 2014
Sedentary behavior (SB) expression and its underlying causal factors have been progressively studied, as it is a major determinant of decreased health quality. In the present study we applied Genotype x Age (GxAge) and Genotype x Sex (GxSex) interaction methods to determine if the phenotypic expression of different SB traits ...
Hachiya Hiroyuki - - 2013
Advanced glycation end products (AGEs) are derivative compounds generated from non-enzymatic glycosylation and oxidation. In comparison with glucose-derived AGEs (Glu-AGEs), glyceraldehyde-derived AGEs (Glycer-AGEs) have stronger toxicity to living systems. In this study, we compared the effects of Glu-AGE and Glycer-AGE on insulin secretion. Rat pancreatic islets were isolated by collagenase ...
Pinheiro Paula C - - 2012
Enhancement of Raman signals of the nucleobase adenine on an Ag based composite was studied using the 1064nm laser line. The composite comprise emulsions of Ag nanoparticles encapsulated in poly(t-butylacrylate) (PtBA) beads that act as substrate for the Surface-Enhanced Raman Scattering (SERS) of adenine. For this system, Raman enhancement was ...
Tang Lin - - 2012
We have developed an optical assay for NADH (Dihydronicotinamide adenine dinucleotide) based on the catalytic growth of gold-silver core-shell nanoparticles (Au-Ag-CSNPs). The nanoparticles were immobilized on pretreated glass slide and are shown to catalyze the NADH-mediated reduction of Ag(I) ions in the presence of 1,4-benzoquinone and cetyltrimethyl ammonium ion. This ...
Hildebrandt Julia C - - 2012
Onchocerca ochengi is a filarial nematode parasite of African cattle and most closely related to Onchocerca volvulus, the causing agent of river blindness. O. ochengi females induce the formation of a nodule in the dermis of the host, in which they remain sedentary in very close association with the host's ...
Zhang Wang-Dong - - 2012
The aggregated lymphoid nodules area (ALNA) in abomasum of Bactrian camels is a special immune structure discovered only in Bactrian camels in recent years (2003). The anatomy research found that there was a close relationship between degree of development, anatomical characteristics and age. To further establish the relationship between histological ...
Tzelepis Flora - - 2012
INTRODUCTION: Only 1%-7% of smokers use quitlines annually. Active telephone recruitment ("cold calling") can enroll about 50% of community smokers to quitline services. However, whether cold-called smokers' characteristics differ from traditional quitline clients is unknown. To assess whether active telephone recruitment reaches new groups of smokers, New South Wales (NSW) ...
Kim By - - 2011
BACKGROUND: Enlarged facial pores have been esthetic problems and have become a matter of cosmetic concern. Several factors are supposed to be related to the enlargement of facial pores, although scientific evaluations were not performed yet. OBJECTIVE: To assess the correlation between facial pores and possible relating factors such as ...
Gemousakakis T - - 2011
Magnetoencephalographic recordings were evaluated in five different states: normal condition, sweet, bitter, sour, and salt taste. Twenty-eight healthy volunteers, 14 male and 14 female, ranging from 12 to 50 years of age, were included in the study. The results showed that, in the normal condition, as well as in the ...
Huhn Ragnar - - 2011
Helium induces preconditioning (He-PC) by mitochondrial calcium-sensitive potassium (mK(Ca)) channel-activation, but this effect is lost in the aged myocardium. Both, the upstream signalling pathway of He-PC and the underlying mechanisms for an age-related loss of preconditioning are unknown. A possible candidate as upstream regulator of mK(Ca) channels is protein kinase ...
Berdjane-Brouk Z - - 2011
We report for the first time the presence of Phlebotomus mascittii and the female of Phlebotomus chadlii in Algeria. These two species were collected during an entomological study conducted in endemic visceral leishmaniasis focus from the north part of the country, Kabylia.
Huang Hsu-Wen - - 2012
Normal aging is accompanied by changes in both structural and functional cerebral organization. Although verbal knowledge seems to be relatively stable across the lifespan, there are age-related changes in the rapid use of that knowledge during on-line language processing. In particular, aging has been linked to reduce effectiveness in preparing ...
Moodie Crawford - - 2012
In the United Kingdom, with most marketing channels prohibited, packaging is one of the few remaining ways that tobacco companies can promote their products. An online survey with young people aged 10-17 years (N = 658) was used to explore why youth choose cigarettes, perceptions of pack color, and perceptions ...
Albedah Abdullah M - - 2011
To draw a profile, and study the media habits for cigarette smokers in Saudi Arabia using the Target Group Index survey (TGI). A household survey using the TGI sample was conducted in March 2008 in 21 cities in Saudi Arabia. A sample of 7003 individuals aged 15 years or more, ...
Dag Omer - - 2011
Periodic mesoporous hydridosilica, PMHS, is shown for the first time to function as both a host and a mild reducing agent towards noble metal ions. In this archetypical study, PMHS microspheres react with aqueous Ag(I) solutions to form Ag(0) nanoparticles housed in different pore locations of the mesostructure. The dominant ...
Teh Andrew W - - 2011
Aims Increasing age is a significant risk factor for developing atrial fibrillation (AF). Pulmonary vein (PV) triggers are critical in the mechanism of AF, but little is known of the substrate changes that occur within the PVs with ageing. Therefore, we sought to identify whether ageing is associated with electroanatomic ...
Wu Yi - - 2011
Whether cumulus cells (CCs) contribute to oocyte aging remains controversial; in that regard, little is known about biochemical processes of gene expression in CCs surrounding aged oocytes. The objective was to elucidate contributions of CCs to porcine oocyte aging and degeneration, apoptosis and BIM expression in CCs during oocyte aging ...
Gmehlin Dennis - - 2011
The frontal hypothesis of aging predicts an age-related decline in cognitive functions requiring inhibitory or attentional regulation. In Alzheimer's disease, preattentive gating out of redundant information is impaired. Our study aimed to examine changes associated with physiological aging in both pre- and early attentive inhibition of recurrent acoustic information. Using ...
Nagesh K R - - 2011
The pore characteristics on the epidermal friction ridges are individualistic and thereby useful in the process of identification when used along with other minutiae details. The present work was undertaken with the objective of studying the sex difference and influence of age on the pore morphology. The study included 230 ...
Leigh-Paffenroth Elizabeth D - - 2011
Background: Hearing loss and age interfere with the auditory system's ability to process temporal changes in the acoustic signal. A key unresolved question is whether high-frequency sensorineural hearing loss (HFSNHL) affects temporal processing in the low-frequency region where hearing loss is minimal or nonexistent. A second unresolved question is whether ...
Tellez James - - 2011
Objective: The function of the sinoatrial node (SAN), the pacemaker of the heart, is known to decline with age, resulting in pacemaker disease in the elderly. The aim of the study was to investigate the effects of ageing on the SAN by characterising electrophysiological changes and determining if changes in ...
Rodriguez-Pallares Jannette - - 2012
Recent studies have shown that renin-angiotensin system overactivation is involved in the aging process in several tissues as well as in longevity and aging-related degenerative diseases by increasing oxidative damage and inflammation. We have recently shown that angiotensin II enhances dopaminergic degeneration by increasing levels of reactive oxygen species and ...
Angelini Viola - - 2012
In this paper we investigate how age affects the self-reported level of life satisfaction among the elderly in Europe. By using a vignette approach, we find evidence that age influences life satisfaction through two counterbalancing channels. On the one hand, controlling for the effects of all other variables, the own ...
Tsiachris Dimitris - - 2011
OBJECTIVE: The age-dependent performance of electrocardiographic (ECG) criteria was examined for left ventricular hypertrophy (LVH) prediction. METHODS: During 2009, 570 middle-aged (54 ± 7 years, 45% men) and 507 elderly (75 ± 6 years, 45% men) inhabitants of the Ikaria Island were studied. Seven ECG criteria were calculated (Sokolow-Lyon voltage ...
Berg A T - - 2011
Epidemiologic evidence suggests the natural history of refractory mesial temporal lobe epilepsy is complicated, yet little is known about the hippocampus from the nontertiary center perspective. In a community-based cohort, individuals with nonsyndromic focal epilepsy with onset <16 years and controls had research MRI scans. Hippocampal (HC) volumes were manually ...
Shrivastav A B - - 2011
Postmortem examination of free-range tigress of Pench Tiger Reserve, MP, India, aged approx 15 years revealed nodule in the pyloric part of the stomach packed with worms and was identified as Gnathostoma spinigerum on the basis of morphology of male and female worms, including eggs.
Nagano Makio - - 2011
Aim:  C-reactive protein (CRP) level predicts future cardiovascular events in patients on haemodialysis (HD). Advanced glycation end products (AGE) play a role in cardiovascular disease (CVD) in HD patients. However, which variables including tissue AGE levels are independently associated with CRP remains unknown. Therefore, whether tissue AGE and CRP levels ...
Guler Hulya - - 2011
Human wound age determination is of prime importance in forensic sciences. Ubiquitin is a small protein required for ATP-dependent, nonlysosomal intracellular protein degradation, which eliminates most of the intracellular defective proteins. Tenascin is an extracellular matrix glycoprotein. The aim of this study was to determine the importance of ubiquitin and ...
Proença Inah Carolina Galatro Faria - - 2011
A history of childhood trauma and the presence of dissociative phenomena are considered to be the most important risk factors for psychogenic nonepileptic seizure disorder (PNESD). This case-control study investigated 20 patients with PNESD and 20 with temporal lobe epilepsy (TLE) diagnosed by video/EEG monitoring who were matched for gender ...
Ma C - - 2011
Background  Metallothioneins (MT) are important antioxidants involved in the ageing process of many tissues and organs. To our knowledge, the role of MT in skin ageing has not been reported. Objectives  To investigate the expression of MT in ageing skin. Methods  The protein levels of MT-I and MT-II in sun-exposed ...
Chu M - - 2011
Background  Scaling skin involves an imbalance between cell proliferation and desquamation, resulting in partially detached corneocytes at the stratum corneum (SC) surface that become visible as they scatter light. Objectives  The purpose of this study was to document scaling skin with no associated pathology, to estimate the range of normal ...
Aydemir Nuran - - 2011
The aims of the study described here were to investigate familiarity with, knowledge of, and attitudes toward epilepsy and to assess indicators of positive attitudes toward epilepsy. Questionnaires previously developed for the Turkish population were used to assess knowledge and attitudes. Data were collected from 1354 randomly selected adults. Three-quarters ...
Hughes Jeffery D - - 2011
Lower urinary tract symptoms (LUTS) are common and prevalence increases with age. In men, voiding symptoms are more commonly encountered than storage symptoms. LUTS are often associated with chronic diseases but their pathophysiology requires further study. We aimed to determine whether calcium channel blockers (CCBs) worsened, improved or did not ...
Datta Hema Sharma - - 2011
Aging is a complex phenomenon, a sum total of changes that occur in a living organism with the passage of time and lead to decreasing ability to survive stress, increasing functional impairment and growing probability of death. There are many theories of aging and skin remains the largest organ of ...
Datta Hema Sharma - - 2011
The traditional Indian medicine-Ayurveda, describes various herbs, fats, oils and minerals with anti-aging as well as wound healing properties. With aging, numerous changes occur in skin, including decrease in tissue cell regeneration, decrease in collagen content, loss of skin elasticity and mechanical strength. We prepared five topical anti-aging formulations using ...
Zanin Mark P - - 2011
How fusion pore formation during exocytosis affects the subsequent release of vesicle contents remains incompletely understood. It is unclear if the amount released per vesicle is dependent upon the nature of the developing fusion pore and whether full fusion and transient kiss and run exocytosis are regulated by similar mechanisms. ...
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