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Nissim Rinat R Department of Psychosocial Oncology and Palliative Care, Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada - - 2014
Studies conducted on hospice volunteers' characteristics and experiences have been cross-sectional. We conducted a prospective study to examine changes in the volunteer experience over time in a cohort of volunteers during the first year of a new residential hospice. Eighty-two active volunteers completed an online baseline survey, and of these, ...
Firebaugh Glenn G , 902 Oswald Tower, University Park, PA, 16802, USA, - - 2014
Lifespans are both shorter and more variable for blacks than for whites in the United States. Because their lifespans are more variable, there is greater inequality in length of life-and thus greater uncertainty about the future-among blacks. This study is the first to decompose the black-white difference in lifespan variability ...
Prunas Antonio A University of Milano-Bicocca, Milan, - - 2014
In Europe, 71 murders resulting in the death of transgendered persons were reported between 2008 and 2013, 20 of which perpetrated in Italy, the second highest rate in Europe after Turkey. We retrospectively analyzed the homicides of transgender people recorded at the Medicolegal Bureau in Milan from January 1993 to ...
Shrira Amit A Interdisciplinary Department of Social Sciences, Bar-Ilan University, Ramat-Gan, - - 2014
the factors that moderate decline in physical functioning as death approaches are understudied. This study aimed to assess death-related decline in global quality of life (QoL) and physical functioning and to test whether baseline QoL moderates terminal decline in physical functioning. four thousand six hundred and fifty-one decedents from the ...
Taniguchi Leandro U - - 2014
IntroductionLimited population-based epidemiologic information about sepsis¿ demography, including its mortality and temporal changes is available from developing countries. We investigated the epidemiology of sepsis deaths in Brazil using secondary data from the Brazilian Mortality Information System.MethodsRetrospective descriptive analysis of Brazilian multiple-cause-of-death data between 2002 and 2010, with sepsis-associated International Classification ...
Chowell Gerardo - - 2014
Scarce information about the epidemiology of historical influenza pandemics in South America prevents complete understanding of pandemic patterns throughout the continent and across different climatic zones. To fill gaps with regard to spatiotemporal patterns of deaths associated with the 1918 influenza pandemic in Chile, we reviewed archival records. We found ...
Peral D D Universidad de Extremadura. Facultad de Medicina. Badajoz. - - 2014
The causes of mortality from nefro-urologic diseases in Jerez de los Caballeros (Badajoz) during the nineteenth century will be our object of study. We have analyzed the death registry books of the parishes in Jerez. The percentage of deaths from nefro-urologic diseases compared to other pathologies is 0.8%, being most ...
Kessaram Tara T University of Otago, Wellington, New - - 2014
This study used Poisson regression modelling to estimate influenza-associated mortality in New Zealand for 1990-2008. Inputs were weekly numbers of deaths and influenza and RSV isolates. Seasonal influenza was associated with an average of 401 medical deaths annually from 1990 to 2008, a rate of 10·6 (95% CI: 7·9, 13·3) ...
Hamill Victoria V University of Glasgow, Robertson Centre for Biostatistics, Glasgow, United Kingdom ; - - 2014
Although the causes of head injury, the population at risk and approaches to prevention and treatment are continually evolving, there is little information about how these are reflected in patterns of mortality over time. We used population based comprehensive data uniquely available in Scotland to investigate changes in the total ...
Sung Kuan-Chin KC Tainan City, Select State, Taiwan ; - - 2014
Abstract Fall-related traumatic brain injury (TBI) death rate is high in older adults in the United States, but little is known regarding trends of these death rates. We sought to examine fall-related TBI death rates by age and sex in older adults from 1980 through 2010 in the United States. ...
Stone Jonathan J Bosch Institute, Sydney, Australia Disciplines of Physiology, Sydney, - - 2014
This review traces evidence that age-related dementia (Alzheimer's disease) results from the destructive impact of the pulse on cerebral vasculature. Evidence is reviewed that the neuropathology of the dementia is caused by the breakdown of small cerebral vessels (silent microbleeds), that the microbleeds result from pulse-induced damage to the cerebral ...
Kumral Bahadir B From the *Department of Forensic Medicine, Namik Kemal University, Faculty of Medicine, Tekirdag; †Department of Forensic Medicine, Abant İzzet Baysal University, Faculty of Medicine, Bolu; ‡Department of Forensic Medicine, Kahramanmaras Sutcu İmam University, Faculty of Medicine, Kahramamaras; §The Ministry of Justice, Council of Forensic Medicine, Istanbul, - - 2014
Hanging is a type of strangulation by means of rope or any other similar material. This kind of ligature strangulation occurs by weight of the body dragging due to gravity and applying force to the neck. Hanging almost never occurs by accident, but occurs mostly as a way to commit ...
Rudd Rose A - - 2014
Nationally, death rates from prescription opioid pain reliever (OPR) overdoses quadrupled during 1999-2010, whereas rates from heroin overdoses increased by <50%. Individual states and cities have reported substantial increases in deaths from heroin overdose since 2010. CDC analyzed recent mortality data from 28 states to determine the scope of the ...
Wingren Carl Johan CJ Department of Forensic Medicine in Lund, The National Board of Forensic Medicine, Sölvegatan 25, SE-223 62 Lund, Sweden; Unit for Forensic Medicine, Department of Clinical Sciences, Faculty of Medicine, Lund University, Lund, Sweden. Electronic address: - - 2014
Obesity is a global problem and in aspects of lethal ethanol intoxications virtually unexplored. The cause of death in ethanol intoxication is generally considered to be suppression of the respiratory function. Previous research indicates that respiratory function is more vulnerable in obese subjects than in those of normal weight. We ...
Norheim Ole F OF Department of Global Public Health and Primary Care, University of Bergen, Norway. Electronic address: - - 2014
The UN will formulate ambitious Sustainable Development Goals for 2030, including one for health. Feasible goals with some quantifiable, measurable targets can influence governments. We propose, as a quatitative health target, "Avoid in each country 40% of premature deaths (under-70 deaths that would be seen in the 2030 population at ...
Mokdad Ali A AA Institute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA. - - 2014
Liver cirrhosis is a major yet largely preventable and underappreciated cause of global health loss. Variations in cirrhosis mortality at the country level reflect differences in prevalence of risk factors such as alcohol use and hepatitis B and C infection. We estimated annual age-specific mortality from liver cirrhosis in 187 ...
Vardoulakis Sotiris S Centre for Radiation, Chemical and Environmental Hazards, Public Health England, Chilton, U.K.; National Centre for Epidemiology and Population Health, Australian National University, Canberra, Australia; and Department of Social and Environmental Health Research, London School of Hygiene and Tropical Medicine, London, - - 2014
Background: High and low ambient temperatures are associated with increased mortality in temperate and subtropical climates. Temperature related mortality patterns are expected to change throughout this century due to climate change. Objectives: We compared mortality associated with heat and cold in UK regions and Australian cities for current and projected ...
Melaku Yohannes Adama - - 2014
In developing countries, investigating mortality levels and causes of death among all age female population despite the childhood and maternal related deaths is important to design appropriate and tailored interventions and to improve survival of female residents. Under Kilite-Awlealo Health and Demographic Surveillance System, we investigated mortality rates and causes ...
Baig Ulfat I - - 2014
Several unresolved issues, paradoxes, and information voids characterize the field of evolution of aging. The recent discovery of aging-like phenomenon in Escherichia coli, marked by asymmetric segregation of damaged components, particularly protein aggregates, has created a number of new possibilities that remain underexplored. Bacterial systems can potentially throw light on ...
Ranjan Abhishek - - 2014
The purpose of this study is to analyze the donor and tissue profile of a community eye bank in Eastern India. Eye bank records were analyzed for the period July 2007-June 2011. Variables analyzed included donor demographics (age, gender, and ethnicity), donor cause of death, consent for recovery, death-to-preservation interval, ...
Hutchinson John P JP University of Nottingham, Epidemiology and Public Health, Nottingham, United Kingdom ; - - 2014
Rationale: Recent evidence from the United Kingdom suggests that the number of deaths from idiopathic pulmonary fibrosis is increasing, although comparable international data are limited. Objectives: We aimed to collate death certification data from multiple countries to determine global trends in mortality from idiopathic pulmonary fibrosis. Methods: Data were obtained ...
Deevska Gergana G University of Kentucky, United - - 2014
In hepatocytes, aging-associated decline in GSH has been linked to activation of neutral sphingomyelinase (nSMase), accumulation of bioactive ceramide and inflammation. In this study, we seek to test whether dietary supplementation with cysteine precursor, L-2-Oxothiazolidine-4-carboxylic acid (OTC), would correct the aging-associated differences in hepatic GSH, nSMase, and ceramide. Young and ...
Straif-Bourgeois Susanne S School of Public Health at Louisiana State University Health Sciences Center in New - - 2014
This report is a purely descriptive study of firearm-related deaths occurring in Louisiana from 1999 to 2010. Mortality data were collected from death certificates from this 12-year period to describe firearm fatalities by year, race, gender, age group, and manner of death (accident, homicide, suicide). Louisiana data were also compared ...
Finsterer Josef - - 2014
Recurrent vomiting due to bulimia associated with abuse of furosemide and laxatives causing severe hypokalemia may result in recurrent aborted sudden cardiac death (SCD) and seizures. We report a 25-year-old female with a history of bulimia associated with abuse of furosemide and laxatives since the age of 15 years, migraine ...
Coban Jale J Department of Biochemistry, Yeditepe University Medical Faculty, Istanbul, - - 2014
Olive leaf (Olea europaea L.) extract (OLE) is a powerful anti-oxidant rich in polyphenols. As oxidative stress plays an important role in aging, we investigated the effect of OLE on oxidative stress in the liver, heart and brain of aged rats. Young (age 3 months) and aged (age 20 months) ...
Tong Haiyan H Environmental Public Health Division, National Health and Environmental Effects Research Laboratory, US Environmental Protection Agency, Research Triangle Park , NC , USA - - 2014
Abstract Context: Epidemiological studies have shown an association between the incidence of adverse cardiovascular effects and exposure to ambient particulate matter (PM). Diesel exhaust (DE) is a major contributor to ambient PM and gaseous emissions in urban areas. Objective: This was a pilot study designed to evaluate concentration-dependent effects of ...
Cho Eun-Min EM Kyung Hee University, College of Environment and Applied Chemistry, Yongin 446-701, Republic of - - 2014
Surface-enhanced Raman scattering (SERS) of an antifungal reagent, myclobutanil (MCB), was performed on Au and Ag nanoparticles (NPs) to estimate the drug-release behaviors in fungal cells. A density functional theory (DFT) calculation was introduced to predict a favorable binding site of MCB to either the Ag or Au atom. Myclobutanil ...
Pandey Ashutosh A Embryotoxicology Section, CSIR-Indian Institute of Toxicology Research, Lucknow, 226001, Uttar Pradesh, - - 2014
Dichloroacetic acid (DCA), a water disinfection by-product, has attained emphasis due to its prospect for clinical use against different diseases including cancer along with negative impact on organisms. However, these reports are based on the toxicological as well clinical data using comparatively higher concentrations of DCA without much of environmental ...
Paredes Jamespaul J Division of Developmental and Cognitive Neuroscience, Yerkes National Primate Research Center of Emory University, 954 Gatewood Drive, Atlanta, GA, 30329, USA, - - 2014
Chimpanzee (Pan troglodytes) and rhesus macaque (Macaca mulatta) and humans (Homo sapiens) share physiological and genetic characteristics, but have remarkably different life spans, with chimpanzees living 50-60 % and the rhesus living 35-40 % of maximum human survival. Since oxidative processes are associated with aging and longevity, we might expect to see ...
Balavandy Sepideh Keshan - - 2014
This study aims to investigate the influence of different stirring time for synthesis of silver nanoparticles in glutathione (GSH) aqueous solution. The silver nanoparticles (Ag-NPs) were prepared by green synthesis method using GSH as reducing agent and stabilizer, under moderate temperature at different stirring times. Silver nitrate (AgNO3) was taken ...
Henrie James - - 2014
Terror Management Theory (TMT) (Greenberg, Pyszczynski, & Solomon, 1986) suggests that culturally-provided worldviews (e.g., religion) may protect individuals from experiencing death anxiety, and several studies have supported this position. However, if one's worldview can offer protection, doubts concerning one's worldview could undermine this protection. The current study investigated whether age, ...
Renard Françoise F Department Public Health and Statistics, Institute of Public Health, Brussels, - - 2014
Reducing premature mortality is a crucial public health objective. After a long gap in the publication of Belgian mortality statistics, this paper presents the leading causes and the regional disparities in premature mortality in 2008-2009 and the changes since 1993. All deaths occurring in the periods 1993-1999 and 2003-2009, in ...
Streatfield P Kim PK Matlab HDSS, Bangladesh; International Centre for Diarrhoeal Disease Research, Bangladesh; INDEPTH Network, Accra, - - 2014
Mortality from non-communicable diseases (NCDs) is a major global issue, as other categories of mortality have diminished and life expectancy has increased. The World Health Organization's Member States have called for a 25% reduction in premature NCD mortality by 2025, which can only be achieved by substantial reductions in risk ...
Alam Nurul N Centre for Population, Urbanization and Climate Change, icddr,b, Dhaka, Bangladesh; - - 2014
Population-based information on causes of death (CoD) by age, sex, and area is critical for countries with limited resources to identify and address key public health issues. This study analysed the demographic surveillance and verbal autopsy (VA) data to estimate age- and sex-specific mortality rates and cause-specific mortality fractions in ...
Awini Elizabeth E Dodowa Health Research Centre, Dodowa, Ghana; School of Public Health, University of Ghana, Accra, Ghana; INDEPTH Network, Accra, Ghana; - - 2014
Data needed to estimate causes of death and the pattern of these deaths are scarce in sub-Saharan Africa. Such data are very important for targeting, monitoring, and evaluating health interventions. To estimate the mortality rate and determine causes of death among adults (aged 15 years and older) in a rural ...
Ndila Carolyne C KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya; INDEPTH Network of Demographic Surveillance Sites, Accra, Ghana; - - 2014
The vast majority of deaths in the Kilifi study area are not recorded through official systems of vital registration. As a result, few data are available regarding causes of death in this population. To describe the causes of death (CODs) among residents of all ages within the Kilifi Health and ...
Jasseh Momodou M Medical Research Council, The Gambia Unit, Fajara, The Gambia; INDEPTH Network, Accra, Ghana; - - 2014
To estimate and evaluate the cause-of-death structure and disease-specific mortality rates in a rural area of The Gambia as determined using the InterVA-4 model. Deaths and person-years of observation were determined by age group for the population of the Farafenni Health and Demographic Surveillance area from January 1998 to December ...
Phillips-Howard Penelope A PA Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, United Kingdom; Centre for Global Health Research, Kenya Medical Research Institute, Kisumu, - - 2014
Non-communicable diseases (NCDs) result in more deaths globally than other causes. Monitoring systems require strengthening to attribute the NCD burden and deaths in low and middle-income countries (LMICs). Data from health and demographic surveillance systems (HDSS) can contribute towards this goal. Between 2003 and 2010, 15,228 deaths in adults aged ...
Mancini Gianni - - 2013
The present work aimed to investigate the effect of (PhSe)2 on cardiovascular age-related oxidative stress in hypercholesterolemic mice. To this end, LDL receptor knockout (LDLr(-/-) ) mice, 3 months (young adult) and 12 months (middle-aged) old, were orally treated with (PhSe)2 . Hypercholesterolemia, regardless of age, impaired the mitochondrial antioxidant ...
Zanobetti Antonella - - 2013
Ambient air pollution has been associated with sudden deaths, some of which are likely due to ventricular arrhythmias. Defibrillator discharge studies have examined the association of air pollution with arrhythmias in sensitive populations. No studies have assessed this association using residence-specific estimates of air pollution exposure. In the Normative Aging ...
Massarsky Andrey - - 2013
Silver nanoparticles (AgNPs) are present in a multitude of consumer and medical products; however, the toxicity of AgNPs is not fully understood. This research aimed to elucidate the relationship between AgNPs cytotoxicity and oxidative stress and damage in rainbow trout (Oncorhynchus mykiss) hepatocytes and erythrocytes in comparison to silver ions ...
Spina Alexander - - 2013
Recent studies have raised concern over possible associations between high selenium (Se) status and excess adiposity, known to be linked to adverse cardio-metabolic outcomes. Studies of Se status in relation to adiposity are scarce in the UK. This study examined cross-sectional associations of anthropometric indices with Se-status biomarkers in a ...
Negishi Takayuki - - 2013
In Japan, people using water from the well contaminated with high level arsenic developed neurological, mostly cerebellar, symptoms, where diphenylarsinic acid (DPAA) was a major compound. Here, we investigated the adverse effects of developmental exposure to 20 mg/L DPAA in drinking water [early period (0-6 weeks of age) and/or late-period ...
Saha Arindam - - 2013
Glutathione (GSH) and oxidized glutathione (GSSG) controls cellular function and efficiency of anticancer therapy. Reliable detection of cellular GSH/GSSG is challenging due to their ultralow concentration (typically femtomolar concentration) and interference by thiol based other molecules. Here we reports a 'turn-off' SERS based approach for reliable detection of cellular GSH ...
Chitty Kate M - - 2013
Alcohol misuse is highly prevalent in bipolar disorder (BD) and has been associated with increased formation of reactive oxygen species in the CNS. Proton magnetic resonance spectroscopy ((1)H-MRS) is an in vivo tissue-based imaging modality that allows the investigation of changes in the brains primary antioxidant, glutathione (GSH), as a ...
Dragicevic Vesna - - 2013
The 2,4-D (2,4-dichlorophenoxyacetic acid) is using as a growth regulator in tissue culture media. Maize seeds have poor ability to maintain germination rate in the long term. To examine the possible restorative effect of homeopathic 2,4-D potencies on maize seedlings originating from seeds damaged by accelerated aging. Seeds of four ...
Kankofer M - - 2013
Antioxidative/oxidative balance is crucial for proper functioning of cells and tissues. It is suggested that this balance can be partly controlled by sex steroid hormones and in consequence can exhibit age- and sex-related dependency. The aim of present study was to describe sex- and age-related changes in the activity of ...
Brasil Aline A - - 2013
Mutations in Cu,Zn-superoxide dismutase (Sod1) have been associated with familial amyotrophic lateral sclerosis (FALS), an age-related disease. Since several studies suggest that oxidative stress plays a central role in neurodegeneration, we aimed to investigate the role of the antioxidant glutathione (GSH) in the activation of human A4V Sod1 during chronological ...
Savery Laura C - - 2013
Pollution of the ocean by mercury (Hg) is a global concern. Hg persists, bioaccumulates and is toxic putting high trophic consumers at risk. The sperm whale (Physeter macrocephalus), is a sentinel of ocean health due to its wide distribution, longevity and high trophic level. Our aim was to survey Hg ...
Han Chul C Department of Aging and Geriatric Research, University of Florida, Gainesville, FL 32610, - - 2013
Reducing calorie intake extends the lifespan of a variety of experimental models and delays progression of age-related hearing loss (AHL). AHL is a common feature of aging and is characterized by age-related decline of hearing associated with loss of sensory hair cells, spiral ganglion neurons, and/or stria vascularis degeneration in ...
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