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Grieshop K K Department of Biological Sciences, University of Cincinnati, Cincinnati, OH, USA; Animal Ecology, Department of Ecology and Genetics, Evolutionary Biology Centre, Uppsala University, Uppsala, - - 2014
The contemporary explanation for the rapid evolutionary diversification of animal genitalia is that such traits evolve by post-copulatory sexual selection. Here, we test the hypothesis that the male genital spines of Drosophila ananassae play an adaptive role in post-copulatory sexual selection. Whereas previous work on two Drosophila species shows that ...
Nardo Lorenzo L *Department of Radiology, University of California San Francisco, San Francisco, CA †Center for Musculoskeletal Health, University of California at Davis School of Medicine, Sacramento, CA ‡California Pacific Medical Research Center, San Francisco, CA §Department of Radiology & Biomedical Imaging, University of California San Francisco, San Francisco, CA ¶Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA ‖Department of Physical Therapy, College of Allied Health Sciences, The University of Tennessee Health Science Center, Memphis, TN **Laboratory of Epidemiology, and Population Sciences, National Institute on Aging, Bethesda, MD; and ††Department of Physical Therapy and Rehabilitation Science, University of California, San Francisco, San Francisco, - - 2014
A descriptive study of the association between diffuse idiopathic skeletal hyperostosis (DISH) and kyphosis. To investigate the association of DISH with Cobb angle of kyphosis in a large cohort of older subjects from the Health Aging and Body Composition Study. DISH and thoracic kyphosis are well-defined radiographical findings in spines ...
Ogurkowska M M University School of Physical Education in Poznan, Department of Biomechanics, Poznań, Poland - - - 2014
Acute injuries or chronic overloading can be the cause of lower back pain. Long--term, highly--specialized training can cause the musculoskeletal system to become overloaded. Field hockey is an example of a sport which, due to the players' non--ergonomic positions, can lead to degenerative changes in the lumbar spine. The aim ...
Yin Ruofeng R aDepartment of Orthopedic Surgery, China-Japan Union Hospital, Jilin University, 126 XianTai Street ChangChun City, JiLin Province China 130033 bDepartment of Orthopaedic Surgery, University of California at Los Angeles, Los Angeles, CA. cDavid Geffen School of Medicine, University of California at Los Angeles, Los Angeles, CA. dDepartment of Orthopaedic Surgery, Keck School of Medicine, University of Southern California, CA 90033, USA eDepartment of Orthopaedic Surgery, Renji Hospital, Shanghai Jiao Tong University School of - - 2014
Study Design. A kinematic magnetic resonance imaging (k-MRI) study.Objective. To investigate the distribution of Schmorl's nodes (SN) in the lumbar spine in healthy adults, and determine the association with lumbar disc degeneration and lumbar spine motion.Summary of Background Data. SNs have been associated with several pathologies of the lumbar spine, ...
Farmer Peter K PK P.K. Farmer, BAppSc(Physio), MMedSc(Physio), Thrive Physiotherapy, Erina, New South Wales, - - 2014
Cervicogenic headache (CGH) is defined as headache symptoms originating from the cervical spine. Cervical dysfunction from abnormal posture has been proposed to aggravate or cause CGH, but there are conflicting reports as to whether there is an association between posture and CGH. To evaluate differences in cervical spinal posture, measured ...
Tan Jiangwei - - 2014
BackgroundIntraoperative assessment of neutral occipitocervical balance during a fusion procedure is challenging. We designed this study to introduce a more comprehensive method of evaluating the occipitocervical neutral position using lateral radiographs.MethodsOne hundred neutral lateral cervical spine radiographs interpreted as normal were studied. Cervical spine radiographs were performed using a standard ...
Andersson Sonia S Department of Women's and Children's Health, Division of Obstetrics and Gynecology, Karolinska Institute, Karolinska University Hospital Solna, Stockholm S-171 76, - - 2014
Human papillomavirus (HPV) 16 is the dominant cofactor in cervical cancer development. The present report investigated the age-specific prevalence of HPV16 in cervical carcinoma in situ (CIS) in females attending organised cervical cancer screening. A retrospective observational study was performed based on individual data from two databases. A total of ...
Nambiar Supriya S Department of Orthodontics and Dentofacial Orthopedics, Manipal College of Dental Sciences, Mangalore, Karnataka, - - 2014
The study was carried out to compare the morphometry of the cervical column between adult Class I and Class II individuals and between gender and to analyze the correlation between the cervical column morphology, the cranial base angle, the craniocervical inclination with craniofacial morphology and stature of Angles Class I ...
Betsch Marcel M Oregon Health and Science University, Department of Orthopaedics and Rehabilitation, Portland, - - 2014
Degeneration of the atlanto-dens and atlanto-axial joints is associated with cervical spine pain and may also be associated with an increased risk of dens fracture. However, there is paucity of literature describing the prevalence of specific degenerative changes in the atlanto-dens and atlanto-axial facet joints. To document age-related degenerative changes ...
Perinetti G G Department of Medical, Surgical and Health Sciences, School of Dentistry, University of Trieste, Trieste, - - 2014
Diagnostic agreement on individual basis between the third middle phalanx maturation (MPM) method and the cervical vertebral maturation (CVM) method has conjecturally been based mainly on overall correlation analyses. Herein, the true agreement between methods according to stage and sex has been evaluated through a comprehensive diagnostic performance analysis. Four ...
Bastir Markus M Paleoanthropology Group, Museo Nacional de Ciencias Naturales, CSIC. J. G. Abascal 2, 28006, Madrid, - - 2014
Sexual dimorphism is important for intraspecific variation and well studied in the human skeleton. In the thoracic part of the spine sexual dimorphism is expected for differences in the respiratory system related to body mass, lung capacity, and energetics, and in the reproductive system for adaptations to pregnancy (lower spine ...
Schlösser Tom P C TP Department of Orthopaedic Surgery, G05.228, University Medical Center Utrecht, P.O. Box 85500, 3508 GA, Utrecht, The Netherlands, - - 2014
Adolescent idiopathic scoliosis occurs far more often in girls than in boys, and its initiation and progression normally takes place around the adolescent growth spurt. Despite extensive research into the topic, no solid explanation for both well-known phenomena has been offered. The sagittal profile of the growing spine has been ...
Munusamy Thangaraj T Department of Neurosurgery, National Neuroscience Institute, 11, Jalan Tan Tock Seng, Singapore, 308433, Singapore, - - 2014
Pedicle screw instrumentation provides optimal stabilization of the cervical spine complex, but is associated with risk of neurovascular injury. Sex and ethnic disparities may compromise safe and accurate screw placement. Therefore, a comprehensive analysis of pedicle dimensions derived from computed tomography scans is pertinent for our multi-ethnic population. Cervical spine ...
Alfred Tamuno T School of Social and Community Medicine, University of Bristol, Canynge Hall, 39 Whatley Road, Bristol, BS8 2PS, UK, - - 2014
The APOE ε2/3/4 genotype has been associated with low-density lipoprotein cholesterol (LDL-C) and Alzheimer disease. However, evidence for associations with measures of cognitive performance in adults without dementia has been mixed, as it is for physical performance. Associations may also be evident in other genotypes implicated in LDL-C levels. As ...
Corley Janie J Department of Psychology,University of Edinburgh,7 George Square,Edinburgh EH8 - - 2014
ABSTRACT Background: We examined the associations between serum cholesterol measures, statin use, and cognitive function measured in childhood and in old age. The possibility that lifelong (trait) cognitive ability accounts for any cross-sectional associations between cholesterol and cognitive performance in older age, seen in observational studies, has not been tested ...
Carinhena Glauber - - 2014
This study was conducted with the aim of adapting the methods developed by Martins and Sakima to assess skeletal maturation by cervical vertebrae in the pubertal growth spurt (PGS) curve. It also aimed to test the reliability and agreement between those methods and the method of hand and wrist radiograph ...
Redondo Olga O 1Social and Cardiovascular Epidemiology Research Group,School of Medicine,University of Alcalá,Alcalá de Henares,Madrid - - 2014
To identify a body fat percentage (%BF) threshold related to an adverse cardiometabolic profile and its surrogate BMI cut-off point. Cross-sectional study. Two public schools in poor urban areas on the outskirts of Guatemala City. A convenience sample of ninety-three healthy, prepubertal, Ladino children (aged 7-12 years). Spearman correlations of ...
Cavallini Gabriella G Interdepartmental Research Centre on Biology and Pathology of Aging Via Roma 55, I-56126 Pisa, Italy. - - 2014
Aging has been defined as a gradually decreasing ability to maintain homeostasis and increasing risk to die. Growing evidence supports malfunctioning with age of quality control system. At an older age, accumulation of altered macromolecules and membranes may impair cell functioning; accumulation of altered mitochondria and peroxisomes may boost the ...
Freitas Wladimir M WM Department of Cardiology, Faculty of Medical Sciences, State University of Campinas Medical School (UNICAMP), Campinas, Sao Paulo, 13084-971, - - 2014
Although low-density lipoprotein cholesterol (LDL-C) has been consistently demonstrated a predictor of atherosclerotic disease in a large spectrum of clinical settings, among individuals aged of 80 years or older this concept is uncertain. This study was evaluated in a carefully selected population if the association between LDL-C and coronary atherosclerotic burden ...
Belcher Britni Ryan BR Cancer Prevention Fellowship Program, Division of Cancer Prevention, Risk Factor Monitoring and Methods Branch, Applied Research Program, National Cancer Institute, Bethesda, - - 2014
Discrepancies in self-report and accelerometer-measured moderate-to-vigorous physical activity (MVPA) may influence relationships with obesity-related biomarkers in youth. Data came from 2003-2006 National Health and Nutrition Examination Surveys (NHANES) for 2174 youth ages 12-19. Biomarkers were: body mass index (BMI, kg/m2), BMI percentile, height and waist circumference (WC, cm), triceps and ...
Keith Dove D Linus Pauling Institute, Oregon State University, United - - 2014
It is well established that lipid metabolism is controlled, in part, by circadian clocks. However, circadian clocks lose temporal precision with age and correlates with elevated incidence in dyslipidemia and metabolic syndrome in older adults. Because our lab has shown that lipoic acid (LA) improves lipid homeostasis in aged animals, ...
Dowd Jennifer B JB Department of Epidemiology and Biostatistics, City University of New York School of Public Health, Hunter College, City University of New York Institute for Demographic Research, City University of New York, New York, New York. Electronic address: - - 2014
People worldwide are becoming obese at earlier ages, increasing exposure to long-term obesity. To examine how BMI at age 25 years predicts later obesity and test the importance of long-term obesity beyond obesity severity for adult cardiovascular, inflammatory, and metabolic risk. Data from adults aged 35-64 years from the 1999-2010 ...
Baughman Penelope P National Institute for Occupational Safety and Health, Morgantown, WV, - - 2014
Policing is considered a high-stress occupation and officers have elevated cardiovascular morbidity and mortality. We evaluated the association between salivary cortisol response to a standardised challenge and the metabolic syndrome (MetSyn), an indicator of increased cardiovascular risk. Cross-sectional data from the Buffalo Cardio-Metabolic Occupational Police Stress Study (2004-2009) were analysed. ...
Martin Mauricio G MG Centro Biología Molecular "Severo Ochoa" CSIC-UAM, Madrid, Spain VIB Center for the Biology of Disease, Center for Human Genetics, University of Leuven (KU Leuven), Leuven, Belgium mauricio.m@immf.uncor.edu - - 2014
Cognitive decline is one of the many characteristics of aging. Reduced long-term potentiation (LTP) and long-term depression (LTD) are thought to be responsible for this decline, although the precise mechanisms underlying LTP and LTD dampening in the old remain unclear. We previously showed that aging is accompanied by the loss ...
Hanssen Nordin M J NM CARIM School for Cardiovascular Diseases, Maastricht University Medical Centre, Maastricht, the - - 2014
Experimental data suggest a role for advanced glycation endproducts (AGEs) in cardiovascular disease (CVD), particularly in type 2 diabetes (T2DM). However, epidemiological evidence of an association between high plasma AGEs and increased cardiovascular risk remains inconclusive. Therefore, in a case-cohort study comprising 134 cardiovascular cases and a random subcohort of ...
Grosman Halina H Clinical Biochemistry Department, Facultad de Farmacia y Bioquímica, INFIBIOC, Universidad de Buenos Aires , Buenos Aires , Argentina - - 2014
Abstract Objective: To evaluate the relationship between testosterone levels and the metabolic syndrome (MS) in men older than 45 years. Methods: Six hundred and sixty men (45-70 years) selected from 2906 participants of a population screening for prostate cancer were included in this study. Testosterone and the components of MS ...
Hawley Nicola L NL Weight Control and Diabetes Research Center, The Miriam Hospital, Providence, Rhode Island; The Alpert Medical School, Brown University, Providence, Rhode - - 2014
To describe the prevalence of obesity-related noncommunicable diseases (NCDs) and associated risk factors in a sample of Samoan adults studied in 2010 as part of a genome-wide assocation study (GWAS) for obesity related traits. Anthropometric and biochemical data collected from n = 3,475 participants (n = 1,437 male; n = ...
Li Wen-Cheng WC Department of Occupation Medicine, Keelung Chang-Gung Memorial Hospital, No. 222, Maijin Rd., Keelung, - - 2014
Obesity, metabolic syndrome (MS), and chronic kidney disease (CKD) are all becoming increasingly prevalent worldwide. Body mass index (BMI) has traditionally been employed to identify overweight or obese individuals, yet multiple studies have yielded conflicting results when BMI was used to evaluate the association between obesity and CKD. The purpose ...
Simino Jeannette J Division of Biostatistics, Washington University in St. Louis, School of Medicine, 660 South Euclid Avenue, Campus Box 8067, Saint Louis, MO 63110-1093, USA. Electronic address: - - 2014
To detect novel loci with age-dependent effects on fasting (≥8 h) levels of total cholesterol, high-density lipoprotein, low-density lipoprotein, and triglycerides using 3600 African Americans, 1283 Asians, 3218 European Americans, and 2026 Mexican Americans from the Family Blood Pressure Program (FBPP). Within each subgroup (defined by network, race, and sex), we ...
Robinson Jennifer J Professor, Departments of Epidemiology & Medicine, University of Iowa. Electronic address: - - 2014
Atherosclerotic cardiovascular disease (ASCVD) is the leading cause of death in developed and developing countries. Despite decades of effort, unhealthy lifestyle habits and ASCVD risk factor levels remain high, and are increasing in many population groups. A new approach to ASCVD prevention is needed. Multiple lines of evidence from animal ...
Flechtner-Mors Marion - - 2014
Objective of the present study was to examine the association between adiponectin and hepatic steatosis, and other biochemical and anthropometric parameters in healthy subjects. A total of 1349 subjects (age 18-65 years) underwent ultrasound examination of the liver. Mean adiponectin concentration for the study collective was 11.35 +/- 6.28 mug/mL. ...
Tritos Nicholas A NA Neuroendocrine Unit (N.A.T., K.K.M., A.K., B.M.K.B.), Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114; Department of Endocrinology (G.J.), Sahlgrenska University Hospital, Gothenburg, Sweden; Department of Endocrinology (M.K.), Barts and the London School of Medicine, Queen Mary University of London, London, United Kingdom; Department of Medical Endocrinology (U.F.-R.), Rigshospitalet, National University Hospital, Copenhagen University, Copenhagen, Denmark; Division of Endocrinology, Diabetes, and Clinical Nutrition (K.C.J.Y.), Oregon Health and Science University, Portland, Oregon; Pfizer, Inc (D.K.), New York, New York; and Pfizer Endocrine Care (P.J.J., M.K.-H.), Sollentuna, - - 2014
Context: GH deficiency (GHD) may occur in adults with cured acromegaly (acroGHD). Objective: Our objective was to examine the effectiveness and safety of GH replacement in acroGHD. Design: This study was a retrospective analysis of data from KIMS (Pfizer International Metabolic Database). Setting: We conducted a pharmaco-epidemiological survey of >16 ...
Yin Z-G ZG Department of Neurology, Daping Hospital, Third Military Medical University, Chongqing, - - 2014
Metabolic syndrome (MetS) has been reported to be associated with silent lacunar infarction, which is highly related to white matter lesions (WMLs). However, little is known about the relationship between MetS and the prevalence of WMLs. The association between MetS, its components and WMLs in middle-aged and elderly patients was ...
Wang Hongyu H Department of Vascular Medicine, Peking University Shougang Hospital , Beijing , P.R. China - - 2014
Abstract Objectives: Arterial stiffness is an independent predictor for vascular diseases. Cardio-ankle vascular index (CAVI) is a new index of arterial stiffness. However, there was little research about the CAVI value between different countries. The aim of the present study was to compare CAVI between Chinese and Japanese subjects and ...
Wang Han-Mei HM Department of Ultrasound, Second Affiliated Hospital of Harbin Medical University, No. 148, Baojian Road, Nangang District, Harbin, 150086, - - 2014
To study the association between known risk factors for cardiovascular disease and intima-media thickness (IMT) in the carotid and popliteal arteries in middle-aged and elderly Chinese adults. 686 middle aged and elderly Chinese adults from the China Da Qing Diabetes Prevention Study who had full clinical, laboratory, ultrasound examination results ...
Clarke-Harris Rebecca R Academic Unit of Human Development and Health, Faculty of Medicine, University of Southampton, Southampton, - - 2014
The early environment, acting via epigenetic processes, is associated with differential risk of cardio-metabolic disease (CMD) which can be predicted by epigenetic marks in proxy tissues. However, such measurements at time points disparate from the health outcome or the environmental exposure may be confounded by intervening stochastic and environmental variation. ...
Kawasumi Koh - - 2014
In dogs, occurrence of lipid metabolism disorders such as obesity and diabetes mellitus has increased markedly in recent years. Hyperlipidemia has been regarded as a common characteristic for obese animals and hyperlipidemic condition may be associated with inflammation, oxidative stress and lipid composition changes. In this study, we investigated the ...
Pinto Camila S CS Endocrinology Division, Diabetes Center, Department of Medicine, Universidade Federal de São Paulo (UNIFESP), São Paulo, - - 2014
The aim of this study was to evaluate subclinical atherosclerosis and related factors in young type 1 diabetes (T1D) patients and healthy peers. Carotid intima-media thickness (cIMT) and anthropometric/laboratorial data were obtained for 83 T1D patients (mean age 19.5 ± 4.0 years, disease duration 9.8 ± 4.8 years) and for ...
Vigna G B GB Medical Department, Azienda Ospedaliera-Universitaria di Ferrara, Ferrara, Italy. Electronic address: - - 2014
The relationships between very high plasma HDLc and subclinical atherosclerosis are still a matter of debate. Twenty subjects with primary hyperalphalipoproteinemia (HAL, with HDLc in the highest 10th percentile and absence of overt secondary causes of this condition), aged 30-65 years, were compared with 20 age and sex-matched controls. Lipid ...
Petrásová Darina - - 2014
Obesity and overweight are major contributors to the global burden of chronic diseases and disability in both majority and minority populations. Data from the cross-sectional population-based HepaMeta study conducted in Slovakia in 2011 were used. The sample comprised a total of 452 Roma. Measurements of special bioactive mediators were taken ...
Nam Ga Eun GE Department of Family Medicine, Korea University College of Medicine, Seoul, South - - 2014
This study aimed to investigate recent trends in the prevalence and parameters of dyslipidemia and rates of lipid-lowering medication use in Korean adults. Trends in lipid profiles in subjects with hypertension, diabetes or obesity were also studied. Data from the Korea National Health and Nutrition Examination Survey in 2005, 2008 ...
Kappelgaard Anne-Marie AM Medical Affairs, Global Marketing GHT, Novo Nordisk A/S, Søborg, - - 2014
Background/Aims: An examination of the effects of up to 260 weeks of growth hormone (GH) therapy on metabolic parameters in Japanese children born small for gestational age (SGA). Methods: Data were analysed from a 156-week extension of a 104-week multicentre, randomised, double-blind, parallel-group trial. Sixty-five children born SGA (age 3-<8 ...
Speeckaert Marijn M MM Department of Nephrology, Ghent University Hospital, Gent, Belgium. Electronic address: - - 2014
As ageing is a complex phenomenon characterized by intraindividual and interindividual diversities in the maintenance of the homeostatic condition of cells and tissues, changes in renal function are not uniform and depend on associated diseases and environmental factors. Multiple studies have investigated the possible underlying mechanisms of age-related decline in ...
Taniguchi Yu Y Research Team for Social Participation and Community Health, Tokyo Metropolitan Institute of Gerontology, 35-2 Sakae-cho, Itabashi-ku, Tokyo 173-0015, Japan. - - 2014
Micronutrients are associated with dementia and cognitive decline among older adults. However, nutritional biomarkers of such decline have not been identified. We attempted to identify nutritional biomarkers that were independent risk markers of cognitive decline in a population of older Japanese. Among 873 cognitively intact adults aged 70 years or ...
Wang Zaimin Z Centre for Chronic Disease, School of Medicine, The University of - - 2014
Objective: To determine trends in health status over a 10-year interval in a high-risk remote Australian Aboriginal community. Methods: Two health surveys were performed, one between 1992 and 1997 and the other between 2004 and 2006, on people aged five years or older. Outcomes were compared across age-matched and sex-matched ...
Scuteri Angelo A San Raffaele Pisana (HSR) IRCCS, Rome, Italy. Electronic address: - - 2014
Specific clusters of metabolic syndrome (MetS) components impact differentially on arterial stiffness, indexed as pulse wave velocity (PWV). Of note, in several population-based studies participating in the MARE (Metabolic syndrome and Arteries REsearch) Consortium the occurrence of specific clusters of MetS differed markedly across Europe and the US. The aim ...
Ando Ayumi A Department of Hygiene and Preventive Medicine, School of Medicine, Iwate Medical University, Yahaba, - - 2014
The objective of this study was to determine the associations of number of teeth with all-cause mortality and cause-specific mortality among middle-aged and elderly Japanese men. A total of 7779 men aged 40-79 years who were free from cardiovascular disease (CVD) were followed up prospectively for 5.6 years. Participants were categorized into ...
Boyne Michael S - - 2014
Abstract An earlier onset of puberty is associated with increased cardiometabolic risk. We investigated whether this relation was independent of faster childhood growth or current size in an Afro-Caribbean birth cohort (n=259). Anthropometry was measured at birth and then 6-monthly. Tanner staging started at age 8 years. Cardiometabolic risk factors ...
Hulmán Adam A Department of Medical Physics and Medical Informatics, University of Szeged, Szeged, Hungary, Department of Epidemiology and Public Health, University College London, London, UK, First Department of Medicine, Semmelweis University Faculty of Medicine, Budapest, Hungary, Steno Diabetes Center, Gentofte, Denmark and Centre de Recherche Public de la Santé, Strassen, - - 2014
Secular trends in cardiovascular risk factors have been described, but few studies have examined simultaneously the effects of both ageing and secular trends within the same cohort. Development of cardiovascular risk factors over the past three decades was analysed using serial measurements from 10 308 participants aged from 35 to ...
Li Chung-Hao CH Department of Family Medicine, Tainan Municipal An-Nan Hospital- China Medical University, - - 2014
Tea has attracted considerable attention for its potential cardioprotective effects. The primary chemical components of tea are thought to have a beneficial effect by reducing arterial stiffness. The objective of this study was to assess the association between tea consumption and brachial-ankle pulse wave velocity (baPWV) in a relatively healthy ...
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