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Results 251 - 300 of 1663
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Sode Miki M Joint Graduate Group in Bioengineering, University of California, San Francisco, CA, USA. - - 2010
Regional variation in trabecular structure across axial sections is often obscured by the conventional global analysis, which takes an average value for the entire trabecular compartment. The objective of this study is to characterize spatial variability in trabecular structure within a cross-section at the distal radius and tibia, and gender ...
Malik Ajay K - - 2010
5-Androstene-3β,7β,17β-triol (β-AET), an active metabolite of dehydroepiandrosterone (DHEA), reversed glucocorticoid (GC)-induced suppression of IL-6, IL-8 and osteoprotegerin production by human osteoblast-like MG-63 cells and promoted osteoblast differentiation of human mesenchymal stem cells (MSCs). In a murine thermal injury model that includes glucocorticoid-induced osteopenia, β-AET significantly (p<0.05) preserved bone mineral content, ...
Kang Bo-Sung - - 2010
The age-related effects on various aspects of swallowing have been reported in studies on the temporal relationship between hyolaryngeal movement and bolus location, as well as the extent of hyolaryngeal movement. However, few studies have described the temporal and spatial relationships concurrently. The main purpose of this study was to ...
Caldas Maria de Paula Mde - - 2010
The aims of this study were to develop a computerized program for objectively evaluating skeletal maturation on cephalometric radiographs, and to apply the new method to Brazilian subjects. The samples were taken from the patient files of Oral Radiological Clinics from the North, Northeast, Midwest and South regions of the ...
Uenishi Kazuhiro - - 2010
There is little evidence regarding the effects of dairy product intake on bone mineralization among late adolescents, especially in Asians. The aim of this study was to determine the association between dairy product intake and bone strength as measured by quantitative ultrasound (QUS) in a large Japanese population. Subjects were ...
Kellinghaus Manuel - - 2010
Determination of the stage of ossification of the medial clavicular epiphysis is a crucial part of age estimation in criminal proceedings when evaluating individuals with completed hand ossification. In order to ensure a maximum of accuracy in forensic age estimation practise, it is recommended to perform thin-slice CT scans; but ...
Djuric Marija - - 2010
Despite evident interest in age-related bone changes, data on regional differences within the proximal femur are scarce. To date, there has been no comprehensive study on site-specific age-related changes in the trabecular architecture of three biomechanically important femoral subregions (medial neck, lateral neck, and intertrochanteric region) for both genders. In ...
Foley S - - 2010
In this large population-based study, walking was assessed twice yearly for a week, each time by pedometer, had consistent clinically important associations with hip areal bone mineral density (aBMD) in both sexes which appears most important in those over 65 years of age suggesting that walking becomes more important with ...
Soto Néstor - - 2011
The aim of this study was to compare the bone mass in young adolescents and adult women with Type 1 diabetes mellitus (T1DM) and determine its relationship with sex steroid and sex hormone-binding globulin (SHBG) levels. Cross-sectional study. We studied a group of adolescents and adult women with T1DM (n=45) ...
El Hage Rawad - - 2009
AIM: The aim of this study was to determine the influence of being overweight on whole-body (WB) bone mineral content (BMC) and bone mineral density (BMD) in a group of Lebanese adolescent girls. METHODS: This study included 32 overweight (BMI>25 kg/m2) adolescent girls (15.3+/-2.3 years old) and 24 maturation-matched (15.7+/-1.7 ...
Lekamwasam Sarath - - 2009
SUMMARY: This study, based on phalangeal bone mineral density (BMD) of 1,174 community dwelling male volunteers aged 50 years or more from seven provinces in Sri Lanka, shows 5.8% prevalence of osteoporosis among them. Advancing age, less physical activity, and low body weight were associated with low BMD. Men with ...
Kuzmychov Oleksii - - 2009
The creep deformation of two acrylic bone cements, Palacos R+G and SmartSet GHV, was investigated for different physical aging times ranging from 45 min to 2 (1/2) years. The experiments were carried out in a three-point-bending set-up in 37 degrees C Ringer's solution applying 10 MPa or 25 MPa creep ...
Baxter-Jones Adam D G AD College of Kinesiology, University of Saskatchewan, SK, - - 2010
To render a diagnosis pediatricians rely upon reference standards for bone mineral density or bone mineral content, which are based on cross-sectional data from a relatively small sample of children. These standards are unable to adequately represent growth in a diverse pediatric population. Thus, the goal of this study was ...
Zhang F F Laboratory of Molecular and Statistical Genetics, College of Life Sciences, Hunan Normal University, Changsha, Hunan, 410081, People's Republic of - - 2010
This study aims at investigating the effects of age, sex, and ethnicity on five femoral neck geometric parameters (FNGPs): femoral neck periosteal diameter, cross-sectional area, cortical thickness, sectional modulus, and buckling ratio and found that the three factors would influence the FNGPs. Bone geometry is one of the most important ...
Verheij J G C - - 2009
OBJECTIVES: In this study age and the trabecular pattern present on dental radiographs were used to predict the presence of osteoporosis. The objective was to evaluate the contribution of the trabecular pattern to the prediction. METHODS: In this project, 671 women between 45 and 71 years of age were recruited. ...
Sherk V D - - 2009
OBJECTIVES: The purposes of this study were to examine tibia bone density and geometry in young and middle aged men, and to explore relationships between pQCT- and DXA-derived body composition variables. METHODS: Healthy males (18-30 years old, n=31; 50-64 years old, n=37) had their total body areal bone mineral density ...
Phoosuwan Manop - - 2009
This study was a preliminary report to investigate the effects of the weight bearing yoga training on both bone resorption marker and the quality of life of the postmenopausal women. The samples were recruited by the purposive sampling from the female Chulalongkorn University staff aged between 50-60 years. The subjects ...
Lumachi Franco - - 2009
The relationship between bone formation markers osteocalcin (OC) and bone-specific alkaline phosphatase (bALP) and age in postmenopausal women was investigated. Forty-eight osteoporotic women (median age 62, range 49-76 years) were enrolled in the study. There were 17 (35%) patients aged 49-59 years (Group A), and 31 (65%) patients aged over ...
Gregg Chris D - - 2009
STUDY DESIGN: Retrospective non-experimental study. OBJECTIVE: To investigate variables associated with active spondylolysis. DESIGN: A retrospective study audited clinical data over a two year period from patients with suspected spondylolysis that were referred for a SPECT bone scan. Six exploratory variables were identified and analysed using uni- and multi-variate regression ...
Zaichick Sofia - - 2010
PROJECT: To understand the role of major, minor, and trace elements in the etiology of bone diseases including osteoporosis, it is necessary to determine the normal levels and age-related changes of bone chemical elements. PROCEDURE: The effect of age and gender on 38 chemical element contents in intact iliac crest ...
Keough N - - 2009
Estimating age at death from adult skeletal remains is a daunting task for human osteologists. For this reason, the evaluation of micro-structural changes in bone with advancing age has become a popular method. However, factors such as nutrition, chronic disease, population group and sex have been suggested to influence the ...
Friedrich Klaus M - - 2010
To assess the imaging findings in Chachapoyan mummies of Peru through multidetector computed tomography (MDCT). Twelve human mummies and three burial objects from Laguna de los Cóndores, Peru, about 500-1000 years old, were studied, using a MDCT unit. In addition to the standard whole-body acquisitions, high-resolution scans from areas of ...
Vicente-Rodríguez G - - 2009
OBJECTIVES: To examine whether different sedentary behaviours are associated with the risk of low bone mineral content in adolescents, and if so, whether extracurricular physical-sporting activity influences this association. MATERIALS AND METHODS: A total of 277 adolescents from Zaragoza (168 females and 109 males) aged 13.0-18.5 yr within frame work ...
Lee Taeyong - - 2009
Although it is known that long cortical bone structurally alter their area moment of inertia with age related bone loss maintaining their bending strength, the incidence of fragility fractures associated with cortical thinning still prevails. We hypothesize that cortical thinning with aging increases the local buckling susceptibility under abnormal or ...
Nie Huiling H Department of Environmental Health, Harvard School of Public Health, Boston, MA, USA. - - 2009
The objective of this study is to investigate the mobilization of lead from bone to blood (endogenous exposure) in a large epidemiologic population. Study subjects were 776 participants in the Normative Aging Study. The subjects had their tibia lead, patella lead, blood lead, and urinary N-telopeptide (NTx) levels measured 1 ...
Chen H - - 2010
We investigated age- and gender-related variation of both cortical and trabecular microstructure in human femoral neck. We found that age-related change of cortical porosity is more noticeable than that of trabecular parameter. Our data may help to gain more insight into the potential mechanism of osteoporotic femoral neck fractures. Variations ...
McNeil Chris J - - 2009
Bone geometry is an important determinant of bone strength and is influenced by muscle pull and weight-bearing. Muscle mass and exposure to weight-bearing decrease with age and thus the purpose of the study was to compare bone geometry of the weight-bearing (tibia) and non-weight-bearing (fibula) bones of the leg in ...
Fintini D - - 2009
Estrogen deficiency in females and androgen deficiency in males may harm periosteal and endosteal apposition, reduce bone size and both cortical and trabecular thickness, modifying in this way the bone structure later in life. To date, few systematic studies on bone mineral density (BMD) and hypogonadism in adolescents are available. ...
Hansen Heather L HL Department of Anthropology, Indiana University, Bloomington, IN 47408, - - 2009
A great deal of research into the determinants of bone strength has unequivocally demonstrated that variation in bone strength is highly subject to genetic factors. Increasing attention in skeletal genetic studies is being paid to indicators of bone quality that complement studies of BMD, including studies of the genetic control ...
Bergot C - - 2009
BACKGROUND: The incidence of osteoporotic hip fractures increases with age, more sharply in women than in men, as a result of qualitative and quantitative bone alterations. Mineralization (a qualitative parameter) showed no differences with age or sex in cancellous bone in earlier studies. Few studies assessed such differences in cortical ...
Gasparrini Marco - - 2009
Increasing marrow adipogenesis plays a causative role in the pathogenesis of age-related bone loss that could be associated with high cytokine production. In this study, we characterized the age-related changes in cytokine expression by bone marrow (BM) adipocytes as compared with subcutaneous (SC) fat. BM and SC adipocytes were isolated ...
Miller Larry E - - 2009
OBJECTIVE: This study assessed the influence of age on the predictors of bone mineral in men. METHODS: Middle-age (n = 41, 54 +/- 4 yrs) and older (n = 40, 69 +/- 5 yrs) men underwent grip and knee extensor strength tests, total body dual-energy X-ray absorptiometry with regional analyses ...
Hill Rebecca J - - 2009
OBJECTIVES: Clinical results of bone mineral density for children with inflammatory bowel disease are commonly reported using reference data for chronological age. It is known that these children, particularly those with Crohn disease, experience delayed growth and maturation. Therefore, it is more appropriate to compare clinical results with bone age ...
Budek A Z - - 2010
Positive correlations for bone mineral content (BMC) between 10 and 17 years of age were found for boys and girls after adjusting for body size, puberty, and diet. This tracking of BMC indicated that osteoporosis prevention should begin already in prepuberty. Previous studies indicate that BMC is tracking during growth, ...
Ji Jong Dae - - 2009
Bone losses in patients with rheumatoid arthritis (RA) include focal marginal joint erosion, juxtaarticular osteopenia, and systemic osteoporosis. Systemic osteoporosis prevalent in RA is associated with increased fracture rates and is a cause of very high morbidity and mortality. A couple of reports showed that advanced glycation end-products (AGEs) influence ...
Wilks D C DC Institute for Biomedical Research into Human Movement and Health, Manchester Metropolitan University, Manchester, - - 2009
Mechanical loading is thought to be a determinant of bone mass and geometry. Both ground reaction forces and tibial strains increase with running speed. This study investigates the hypothesis that surrogates of bone strength in male and female master sprinters, middle and long distance runners and race-walkers vary according to ...
Iuliano-Burns Sandra - - 2009
BACKGROUND: Taller stature and larger bone size in males are attributed to more rapid growth than in females. However, comparing sexes of the same age mismatches by pubertal stage, so males will be less mature than females. Comparing sexes of the same pubertal stage mismatches by age, so males will ...
Harth Sebastian - - 2009
Estimating age from the skeletons of adults is difficult. The accuracy decreases for old age. Ossification of the neurocranial sutures has been used as an age characteristic since Broca's time (1824-1880). Although the sutures traverse the bone, current approaches only encompass the ecto- and endocranial sutures. Evaluating the cross-section of ...
Han Seung-Ho - - 2009
The purpose of this study was to develop age-predicting equations from the anterior cortex of the femur of Korean adults. Seventy-two femoral samples (44 male and 28 female) were obtained from Korean cadavers and used to develop the equations. The thin sections (<100-microm thick) were prepared by manual grinding; the ...
Jackowski Stefan A - - 2009
PURPOSE: We examined the timing of the age and the magnitude of peak lean tissue mass accrual (PLTV) relative to the age and magnitude of two variables of bone strength [peak cross sectional area velocity (PCSAV), and peak section modulus velocity, (PZV)] at the proximal femur in males and females ...
Messaaoui Anissa - - 2009
To our knowledge, only two controversial articles have reported the study of bone age at diagnosis in diabetic children. The aim of this study was to compare chronological age with bone age and to evaluate the impact of A1C on bone age in children at diagnosis of type 1 diabetes. ...
Bellantuono Ilaria - - 2009
Marrow stromal cells (MSC) are thought to be stem cells with osteogenic potential and therefore responsible for the repair and maintenance of the skeleton. Age related bone loss is one of the most prevalent diseases in the elder population. It is controversial whether MSC undergo a process of aging in ...
Leng Huijie H Department of Orthopaedics, Peking University Third Hospital, Beijing 100191, - - 2009
In this study, a progressive loading regimen (load-dwell-unloading-dwell-reloading) was applied on bone samples to examine the compressive post-yield response of bone at increasing strain levels. Cortical bone specimens from human tibiae of two age groups (middle-aged group: 53+/-2 years, 4 females and 4 males, elderly group: 83+/-6 years, 4 females ...
Dalzell N - - 2009
We recruited a population-based sample of 58 males and 74 females aged 20-79 from a primary care medical practice to provide normative and descriptive data for high-resolution peripheral quantitative computed tomography (pQCT) parameters. Important effects of ageing and contrasts in the effects of sex on the micro-architecture and strength of ...
Berenson A B AB Department of Obstetrics and Gynecology and the Center for Interdisciplinary Research in Women's Health, University of Texas Medical Branch, Galveston, TX, USA. - - 2009
Racial/ethnic differences were observed in age at peak bone density and their correlates, with whites peaking at least 5 years earlier at the femoral neck than black and Hispanic women. Race-specific standards generated in this study could be useful when interpreting bone densitometry data in young women. The influence of ...
Wehrbein Heinrich - - 2009
OBJECTIVE: The aim of the present study was to quantitatively assess the bone quality of the palatal bone from an implantologic standpoint. MATERIAL AND METHODS: The material consisted of palatal tissue blocks of autopsy material from 22 subjects (19 male, three female), between 18 and 63 years of age. The ...
Delahunty K M - - 2009
Seasonal variation in bone mineral density (BMD) has been documented in humans, and has been attributed to changes in 25-hydroxyvitamin D [25(OH)D] synthesis. To test the hypothesis that seasonal changes in bone mass occur in laboratory mice, we measured body composition, femoral bone phenotypes, and serum bone markers in 16-wk-old ...
Kumar K - - 2009
Survey radiographs of all the growing dogs aged up to 6 months, which were presented to the IVRI polyclinics during the 10 year period were screened to study the determinants of bone mass, density and growth. On the basis of clinical history and radiographic evaluation of long bones, the cases ...
Swoboda Kathryn J KJ Departments of Neurology, Pediatrics, Neonatology and General Clinical Research Center, University of Utah School of Medicine, Salt Lake City, Utah, United States of - - 2009
Preliminary in vitro and in vivo studies with valproic acid (VPA) in cell lines and patients with spinal muscular atrophy (SMA) demonstrate increased expression of SMN, supporting the possibility of therapeutic benefit. We performed an open label trial of VPA in 42 subjects with SMA to assess safety and explore ...
Mogliazza Silvia - - 2009
This paper regards the discovery of a trepanated skull dating back to the end of the Middle Bronze Age II (1650-1600 B.C.). The skull was found in a funeral pit in the Syrian city of Ebla. A rectangular area of the frontal bone measuring approximately 50 by 45 mm was ...
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