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Boyne Michael S - - 2014
Abstract An earlier onset of puberty is associated with increased cardiometabolic risk. We investigated whether this relation was independent of faster childhood growth or current size in an Afro-Caribbean birth cohort (n=259). Anthropometry was measured at birth and then 6-monthly. Tanner staging started at age 8 years. Cardiometabolic risk factors ...
Hulmán Adam A Department of Medical Physics and Medical Informatics, University of Szeged, Szeged, Hungary, Department of Epidemiology and Public Health, University College London, London, UK, First Department of Medicine, Semmelweis University Faculty of Medicine, Budapest, Hungary, Steno Diabetes Center, Gentofte, Denmark and Centre de Recherche Public de la Santé, Strassen, - - 2014
Secular trends in cardiovascular risk factors have been described, but few studies have examined simultaneously the effects of both ageing and secular trends within the same cohort. Development of cardiovascular risk factors over the past three decades was analysed using serial measurements from 10 308 participants aged from 35 to ...
Li Chung-Hao CH Department of Family Medicine, Tainan Municipal An-Nan Hospital- China Medical University, - - 2014
Tea has attracted considerable attention for its potential cardioprotective effects. The primary chemical components of tea are thought to have a beneficial effect by reducing arterial stiffness. The objective of this study was to assess the association between tea consumption and brachial-ankle pulse wave velocity (baPWV) in a relatively healthy ...
Aslan Raziye R Department of Family Medicine, Meram Medical Faculty, University of Konya, Turkey. Electronic address: - - 2014
In this study, we aimed to assess the total antioxidant status (TAS), total oxidant status (TOS) and paraoxonase activity (PON1) in smokers and nonsmokers. This cross-sectional analytical study was conducted on 100 smokers and 100 nonsmokers. Low-density lipoprotein cholesterol (LDL-c), high-density lipoprotein cholesterol (HDL-c), total cholesterol (TC), triglyceride (TG), fasting ...
Mulero J J Department of Food Technology and Nutrition, Catholic University of San Antonio, Murcia, - - 2014
Age-related macular degeneration (AMD) is the leading cause of irreversible visual impairment and blindness among persons aged 60 years and older and many theories exist and feature mechanisms of oxidative stress, atherosclerotic-like changes, genetic predisposition, and inflammation in development of AMD. The aim of this study was to evaluate the ...
Bertolotti Marco M Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, - - 2014
The modifications of cholesterol metabolism associated with aging are ill-defined. The objective of this study was to define age-associated alterations of the different metabolic pathways controlling cholesterol homeostasis by analyzing circulating sterols. We analyzed serum samples collected from 201 adult (75 male, 126 female) subjects within the epidemiological MICOL study ...
Zamuner Marina M Faculty of Medicine, Pontifical Catholic University of Campinas (PUC-Campinas), 13060-904 Campinas, SP, - - 2014
To define whether the association of male lower urinary tract symptoms (LUTS) and metabolic syndrome (MS) is real or simply an epiphenomenon, 490 male adults (mean age 58 ± 9 years) underwent International Prostate Symptom Score (IPSS), physical and prostate digital examinations, blood analysis, and urinary tract transabdominal ultrasound with ...
Sato Kimiko K Prefectural University of - - 2014
Objectives: We examined the factors considered to change body composition and blood biochemistry indicators in menopausal middle-aged and elderly women. These changes result from exercise by walking as part of their daily activities and lemon consumption by women who live on the small islands of the Seto Inland Sea, Japan's ...
Marianecci Carlotta C Department of Drug Chemistry and Technologies, University Sapienza of Rome, Rome, - - 2014
Liquorice extracts demonstrate therapeutic efficacy in treating dermatitis, eczema, and psoriasis when compared with corticosteroids. In this work, nonionic surfactant vesicles (niosomes, NSVs) containing polysorbate 20 (Tween 20), cholesterol, and cholesteryl hemisuccinate at different molar concentrations were used to prepare monoammonium glycyrrhizinate (AG)-loaded NSVs. The anti-inflammatory properties of AG-loaded NSVs ...
Salinas Jennifer J JJ University of Texas Health Science Center, School of Public Health, Brownsville Campus, 80 Fort Brown, Brownsville, TX 78520. E-mail: - - 2014
Although the relationship between health behaviors and outcomes such as smoking and obesity with longer residence in the United States among Mexican American immigrants is established, the relationship between length of residency in the United States and risk for cardiovascular disease (CVD) is not fully understood. The objective of this ...
Spagnuolo Maria Stefania MS Department of Bio-Agrofood Science, Institute of Animal Production Systems in Mediterranean Environments, National Research Council Naples, - - 2014
Alteration in cholesterol metabolism has been implicated in the pathogenesis of several neurodegenerative disorders. Apolipoprotein E (ApoE) is the major component of brain lipoproteins supporting cholesterol transport. We previously reported that the acute-phase protein Haptoglobin (Hpt) binds ApoE, and influences its function in blood cholesterol homeostasis. Major aim of this ...
Arbour Victoria M VM Department of Biological Sciences, University of Alberta, Edmonton, Alberta, - - 2014
A new ankylosaurid (Ankylosauria: Dinosauria), Ziapelta sanjuanensis, gen. et sp. nov., is based on a complete skull, an incomplete first cervical half ring, a possible fragment of the second cervical half ring, and additional fragmentary osteoderms. The holotype specimen is from the Upper Cretaceous (Upper Campanian, Kirtlandian Land-Vertebrate Age) Kirtland ...
Yin Ze-Gang ZG Department of Neurology, Daping Hospital and Institute of Field Surgery, Third Military Medical University, Chongqing, - - 2014
Apolipoprotein A-I (apoA-I), the major protein for high density lipoprotein, is essential for reverse cholesterol transport. Decreased serum levels of apoA-I have been reported to correlate with subcortical infarction and dementia, both of which are highly related to white matter lesions (WMLs). However, the association between apoA-I and WMLs has ...
Shin Jeong Ah JA Division of Endocrinology and Metabolism, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, 222 Banpo-daero, Seocho-gu, Seoul 137-701, Republic of - - 2014
We investigated whether thyroid function could identify obesity phenotype in euthyroid subjects. A cross-sectional analysis was performed among nondiabetic, euthyroid subjects. We stratified subjects into four groups by BMI and insulin resistance (IR). Of 6241 subjects, 33.8% were overweight or obese (OW/OB) and 66.2% were normal weight (NW). Free thyroxine ...
He Chih-Tsueng CT 0000-0002-1918-5186 Department of Internal Medicine, Tri-Service General Hospital Songshan Branch, Taipei 10581, Taiwan ; Division of Endocrinology and Metabolism, Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical Center, No. 325, Section 2, Chenggong Road, Neihu District, Taipei City 11490, - - 2014
The aim of this cross-sectional study was to investigate the relationship between soluble form of receptor for advanced glycation end products (sRAGE), obesity, and metabolic syndrome (MetS) in adolescents. A total of 522 male and 561 female adolescents were enrolled into the final analyses. Anthropometric parameters, blood pressure, blood biochemistry, ...
Sharma Kaushal K Neuroscience Research Lab, Department of Neurology, Post Graduate Institute of Medical Education and Research Chandigarh, - - 2014
Ageing disorders can be defined as the progressive and cumulative outcome of several defective cellular mechanisms as well as metabolic pathways, consequently resulting in degeneration. Environment plays an important role in its pathogenesis. In contrast, developmental disorders arise from inherited mutations and usually the role of environmental factors in development ...
Kaess Bernhard M BM Department of Cardiovascular Sciences, University of Leicester, Leicester, United Kingdom ; Deutsches Herzzentrum, Technische Universität, Munich, Germany ; Department for Internal Medicine II, University Hospital Regensburg, Regensburg, - - 2014
The impact of fast changes in obesity indices on other measures of metabolic health is poorly defined in the general population. Using the Polish accession to the European Union as a model of political and social transformation we examined how an expected rapid increase in body mass index (BMI) and ...
Kim J J Division of Biological Sciences, University of California, 9500 Gilman Drive, La Jolla, CA, - - 2014
p53 is an important inducer of organismal aging. However, its roles in the aging of skin remain unclear. Here we show that mice with chronic activation of p53 develop an aging phenotype in the skin associated with a reduction of subcutaneous fat and loss of sebaceous gland (SG). The reduction ...
Koyama Satomi S Departments of Pediatrics, - - 2013
OBJECTIVE:The age of adiposity rebound (AR) is defined as the time at which BMI starts to rise after infancy and is thought to be a marker of later obesity. To determine whether this age is related to future occurrence of metabolic syndrome, we investigated the relationship of the timing of ...
Milman Sofiya - - 2013
A change in the lipoprotein profile is a metabolic hallmark of aging and has been the target for modern medical developments. Although pharmaceutical interventions aimed at lipid lowering substantially decrease the risk of cardiovascular disease, they have much less impact on mortality and longevity. Moreover, they have not affected death ...
Miedema Michael D MD Brigham and Women's Hospital, Division of Aging, and Boston Veteran Affairs Healthcare System, Harvard Medical School, Boston, - - 2014
Adult height has been hypothesized to be inversely associated with coronary heart disease; however, studies have produced conflicting results. We sought to examine the relationship between adult height and the prevalence of coronary artery calcium (CAC), a direct measure of subclinical atherosclerosis and surrogate marker of coronary heart disease. We ...
Mikkelsen U R - - 2013
Human aging is associated with a loss of skeletal muscle and an increase in circulating inflammatory markers. It is unknown whether endurance training (Tr) can prevent these changes. Therefore we studied 15 old trained (O-Tr) healthy males and, for comparison, 12 old untrained (O-Un), 10 Young-Tr (Y-Tr) and 12 Young-Un ...
Pan Jian Gang - - 2013
Objectives: To evaluate the relationship between metabolic syndrome (MetS) and annual prostate growth rates in Chinese patients of different age decades with benign prostatic hyperplasia (BPH). Methods: We retrospectively analyzed the clinical data obtained from 1,052 Chinese men with BPH. Overnight fasting venous blood specimens were collected and serum levels ...
Wendell Carrington R - - 2013
Objective: Prior literature has identified inconsistent longitudinal associations between total cholesterol and cognitive decline. The authors examined prospective nonlinear relations of coincident trajectories of total cholesterol and cognitive function among persons free of stroke, dementia, and other neurological disease. Method: Up to 1,601 participants from the Baltimore Longitudinal Study of ...
Keefer Daniel J - - 2013
The purpose of this investigation was to determine if waist-to-height ratio (WHTR) or body mass index (BMI) is the better indicator of cardiovascular disease risk in children and adolescents of varying ages. Data from children and adolescents (N = 2300) who were part of the 2003-2004 National Health and Nutrition Examination Survey ...
Mutombo Paulin Beya Wa Bitadi - - 2013
Abstract Background: Type 2 diabetes (T2D) is among the leading public health problems in Japan, and glycated hemoglobin (HbA1c) can be used to screen the population for T2D. Gene polymorphisms, known to be associated with obesity, may predispose individuals to T2D. Rs17782313 the melanocortin 4 receptor (MC4R) has shown one ...
Eberhard Jörg - - 2013
To investigate the association between periodontal disease severity and cardiorespiratory fitness (CRF) in a cross-sectional study of sedentary men. Seventy-two healthy men (45 to 65 years) who did not join any sport activity and had a preferentially sitting working position were recruited. Periodontal status was recorded and CRF was measured ...
Koutseff Alexis - - 2013
Apolipoprotein E (ApoE) is found in three different forms in humans (ApoE2, ApoE3 and ApoE4), and ApoE polymorphism is recognized as a major risk factor for Alzheimer's disease (AD). ApoE is involved in lipid and cholesterol transport, cell repair, and amyloid-β deposition and certain studies suggest potential implications in neurogenesis. ...
Dai Shifan - - 2013
To estimate age-related changes for serum concentration of non-high-density lipoprotein cholesterol (HDL-C), describe non-HDL-C distribution, and examine the prevalence of high non-HDL-C levels in children and adolescents by demographic characteristics and weight status. Data from 7058 participants ages 6-19 years in the 2005-2010 National Health and Nutrition Examination Surveys were ...
Fahed Akl C - - 2013
Intima-media thickness (IMT) is a well-described marker of cardiovascular disease. In this study we aim to determine whether low-density lipoprotein (LDL) levels and disease-related mutation status can predict IMT in patients with severe familial hypercholesterolemia (FH) referred for or on LDL apheresis. Genetic screening, lipid profile testing, and IMT measurements ...
Usui Shiho - - 2013
The objectives of this study were to set specific dog breed and sex standards for total cholesterol (T-Cho) and total triglyceride (T-TG) concentrations in dogs and to quantify the associations between dog age and concentrations of both lipids for different breeds. Increased age was associated with higher T-Cho and T-TG ...
Dumurgier Julien - - 2013
Vascular risk factors contribute to motor decline in the elderly persons. We investigated the relationship between lipid-lowering drugs (LLDs) use and decline in walking speed (WS) in older adults. Data on 4,009 community-dwelling men and women, aged ≥65 years at baseline, are drawn from the Dijon (France) center of the ...
Vashum Khanrin P - - 2013
The aim of this research is to estimate the prevalence of excessive daytime sleepiness in an older population and associations with sociodemographic, health, and lifestyle factors using a cross-sectional, population-based study. Participants were men (1560) and women (1759), aged 55 to 85 years, enrolled in the Hunter Community Study, a ...
Jacobs Jeremy M - - 2013
The importance of cholesterol as a risk factor among older people, particularly among the very old, is controversial. Whether or not hypercholesterolemia warrants medical concern, and whether statins are beneficial among very old people, remain unresolved common clinical dilemmas. This study examines whether increased total cholesterol (TC) was associated with ...
Suwatanaviroj Tan T Nopparat Rajathanee Hospital, Bangkok, Thailand. - - 2013
To compare the prevalence of coronary artery disease (CAD) between Thai Muslim and Thai Buddhist patients. A hospital based retrospective study was carried out to investigate the prevalence of CAD and cardiovascular risk factors of these two ethnic and religious groups at Nopparat Rajathanee Hospital between June 2012 and December ...
Roy A A Department of Biochemistry, Medical College, College Street, Kolkata, West Bengal, - - 2013
Coronary Heart Disease (CHD) is the leading cause of death in many developed countries. The relation between heart rate variability (HRV) and CHD was recently explored after the development of HRV techniques. Lower HRV was proven to be associated with a greater risk for developing hypertension among normotensive men, and ...
Smiljanic Kosara - - 2013
Disturbance of cholesterol homeostasis in the brain is coupled to age-related brain dysfunction. In the present work, we studied the relationship between aging and cholesterol metabolism in two brain regions, the cortex and hippocampus, as well as in the sera and liver of 6-, 12-, 18- and 24-month-old male Wistar ...
Xu Yan-Ping YP Yan-Ping Xu, Jun-Fen Fu, Department of Endocrinology, Children's Hospital of Zhejiang University School of Medicine, Hangzhou 310003, Zhejiang Province, - - 2013
To confirm the hypothesis that polymorphisms of the uncoupling protein 3 (UCP3) gene are associated with the occurrence of nonalcoholic fatty liver disease (NAFLD). A total of 250 NAFLD patients (147 males and 103 females) and 200 healthy individuals who served as controls (control, 109 males and 91 females), aged ...
Seidlerová Jitka - - 2013
Aortic stiffness is strongly related to age and mean arterial pressure (MAP). In the present analysis, we investigated whether antihypertensive treatment modulates the association of the aortic pulse wave velocity (PWV) with age and with MAP in the general population. In the Czech post-MONICA cross-sectional study, we measured the PWV ...
Marsh-Hunkin K Erica - - 2013
Estrogens activate male-typical sexual behavior in several mammalian and avian models. Estrogen signaling also appears critical in the control of sex change in some fishes, in which it is instead decreases in estradiol levels that may permit development of male-typical behaviors. The bluehead wrasse is a protogynous hermaphrodite that exhibits ...
Heir Trond - - 2013
Few studies have examined how various lifestyle factors in midlife predict longevity, and none of these studies have examined the impact of physical fitness. The present study aimed to examine longevity in relation to smoking, overweight and physical fitness. We prospectively studied longevity (defined as reaching at least 85 years ...
Han Young Sang - - 2013
Aim: To evaluate the relationship between intraocular pressure (IOP) and systemic health parameters such as age, gender, body mass index (BMI), total cholesterol, high density lipoprotein (HDL), and triglyceride (TG) in a Korean population. Materials and Methods: A total of 30,893 healthy subjects underwent automated multiphasic tests, including non-contact tonometry, ...
Beltrán-Sánchez Hiram H Center for Population & Development Studies, Harvard University, 9 Bow Street, Cambridge, MA, 02138, USA, - - 2013
Mexico has experienced changes in its demographic and epidemiologic profile accompanied by recent changes in nutrition and income. Thus, the old and the young have experienced very different environments. Using data from the Mexican National Health Nutrition Survey 2006, we examine age and sex differences in physiological status and dysregulation ...
Iancu M - - 2013
Obesity is associated with high prevalence of coronary heart disease (CHD) and long term increased cardiovascular morbi-mortality. There are no data regarding the effect of laparoscopic sleeve gastrectomy (LSG) on long-term CHD - risk. It is known that "a man is as old as his arteries" and this concept is ...
Bergholdt Helle K M - - 2013
The aim of this article was to describe the study design, participants and baseline characteristics of The Danish General Suburban Population Study (GESUS) and to compare suburban participants with age- and gender-matched urban participants from the Copenhagen General Population Study (CGPS). Data from questionnaire, health examination, biochemical measurements and public ...
Gong Chun-Dan - - 2013
The prevalence of adolescents' obesity and overweight has dramatically elevated in China. Obese children were likely to have hypertension, high insulin and dyslipidemia, which are risk factors of cardiovascular diseases. However there was no cut-off point of anthropometric values to predict the risk factors in Chinese adolescents. The present study ...
Laudisio Alice - - 2013
Metabolic syndrome (MetS) is associated with incident disability in middle-aged subjects. We evaluated the association of MetS with functional ability in an older population. We enrolled 1155 participants aged 65+, derived from the InCHIANTI study, and followed for 3 years. MetS was diagnosed according to the National Cholesterol Education Program's ...
Gonzalez-Covarrubias Vanessa - - 2013
The role of classical lipids in aging diseases and human longevity has been widely acknowledged. Triglyceride and cholesterol concentrations are clinically assessed to infer the risk of cardiovascular disease while larger lipoprotein particle size and low triglyceride levels have been identified as markers of human longevity. The rise of lipidomics ...
Wang Yi - - 2013
To investigate the association between metabolic syndrome (MetS) and the National Institutes of Health-Chronic Prostatitis Symptom Index (NIH-CPSI) in a population-based sample of Chinese men. From October 2010 to July 2011, 1896 men, aged between 20 and 50 years, residing in Shijingshan district of Beijing, China, were selected to participate ...
Akadam-Teker Basak - - 2013
Hydroxymethylglutaryl-Coenzyme A Reductase (HMGCR) catalyzes the rate-limiting step of cholesterol biosynthesis. This enzyme is the target of the widely available cholesterol lowering statins. In this population-based case-control study, the frequencies of -911 C>A polymorphism (rs3761740) of the HMGCR gene in patients with coronary heart disease (CHD) and healthy subjects were ...
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