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Smith-Parrish Melissa M Division of Pediatric Cardiology, Department of Pediatrics, University of Michigan, Ann Arbor, MI. Electronic address: - - 2014
To determine whether patients with coarctation of the aorta (COA) were more likely to develop obesity compared with the general population or others with isolated forms of congenital heart disease. We conducted a cross-sectional study of 160 patients who underwent COA repair at our institution between 1974 and 2009. Body ...
Contractor Tahmeed T 1Division of Cardiology, Lehigh Valley Health Network, Allentown, PA; 2Department of Clinical Cardiac Electrophysiology, Kaiser Permanente Los Angeles Medical Center, Los Angeles, CA; 3Department of Epidemiology and Biostatistics, Michigan State University, East Lansing, MI; 4Center for Health Research, Geisinger Health System, Danville, PA; and 5Department of Medicine, Michigan State University, East Lansing, - - 2014
Previous case reports and small studies have suggested that 3-hydroxy-3-methylglutaryl-CoA reductase inhibitors (HMG-CoA-Is) may increase the risk of tendon rupture. We conducted a population-based retrospective cohort evaluation to better assess this relationship. From approximately 800,000 enrollees of a private insurance database, those who were aged ≤64 years with at least ...
Nass Ralf - - 2013
Background:Acyl-ghrelin is thought to have both orexigenic effects and to stimulate growth hormone (GH) release. A possible cause of the anorexia of aging is an age-dependent decrease in circulating acyl-ghrelin levels.Objectives:The purpose of the study was to compare acyl-ghrelin and GH concentrations between healthy old and young adults and to ...
Fukami Kei - - 2013
Background and Aims: Advanced glycation end products (AGEs) contribute to cardiovascular disease in patients with hemodialysis. We have recently found that carnitine levels are inversely associated with skin AGE levels in hemodialysis patients. We examined whether L-carnitine supplementation reduced skin AGE levels in hemodialysis patients with carnitine deficiency. Methods: This ...
Delhanty Patric J - - 2013
Unacylated ghrelin (UAG), or des-acyl ghrelin, is slowly fighting its way up into the field of interest that studies preproghrelin gene-encoded peptides. Long considered to be an inert degradation product of (acylated) ghrelin (AG), UAG nowadays emerges as an important hormone, separate from the other proghrelin-derived peptides, AG and obestatin. ...
Cook Stephen C - - 2012
AIMS: There is a fivefold increase in the frequency of intracranial aneurysm (IA) in adults with coarctation of the aorta (CoA). Current guidelines for management of adults with CoA recommend computed tomography angiography (CTA) or magnetic resonance imaging of the intracranial vessels. However, this recommendation has not been universally accepted. ...
Li Qingyou - - 2011
One vexing issue in biomedical research is the failure of many therapies to translate from success in animal models to effective treatment of human disease. One significant difference between the animal models and the human disease is the age of the subject. Cancer, stroke and Alzheimer's occur mainly in humans ...
Mannix Rebekah C - - 2011
β-Amyloid (Aβ) peptides, most notably associated with Alzheimer's disease, have been implicated in the pathogenesis of secondary injury after traumatic brain injury (TBI). A prior study has demonstrated that blocking the β-site amyloid precursor protein (APP)-cleaving enzyme 1 (Bace1) required for production of Aβ from APP improved functional and histologic ...
Bogl Leonie H - - 2011
The purpose of this study was to investigate the relationship of fat mass (FM) and lean mass (LM) with bone mineral density (BMD) independent of genetic effects. We also assessed the extent to which genetic and environmental influences explain the associations between these phenotypes. Body composition and BMD were measured ...
GruodytÄ— R - - 2010
 To evaluate the relationships of visfatin, adiponectin and leptin with bone mineral density (BMD) and bone mineral content (BMC) in adolescent female athletes with different training patterns. This study involved 170 healthy 13-15-year-old girls divided into six groups based on activity: sport games (i.e. basketball, volleyball, badminton) (n=49), track sprint ...
Bleicher K - - 2011
Aging alone is not the only factor accounting for poor bone health in older men. There are modifiable factors and lifestyle choices that may influence bone health and result in higher bone density and lower fracture risk even in very old men. The aim of this cross-sectional analysis was to ...
Lee Jung-Hee - - 2010
Retrospective study. To define the relationship between pelvic parameters and lumbar spinal disorders including spinal stenosis, spondylolisthesis, and lumbar degenerative kyphosis (LDK). Although numerous studies have investigated the relationship between various lumbar spinal disorders and spinal parameters previously, none has reported on the relationship with LDK. The present study analyzed ...
Kim Kwang-Il - - 2011
It has not been clearly defined whether reduced bone mineral density (BMD) is a direct risk factor of vascular calcification. A total of 2,160 subjects who were older than 50 years and underwent routine health examination at the Seoul National University Hospital Healthcare System Gangnam Center were included in this study. ...
Breukhoven Petra E - - 2011
Previous studies showed conflicting data on the effect of prematurity on bone mineral density (BMD) in infants and children. Only a few studies investigated the long-term effects of prematurity on BMD in early adulthood. The objective of our study was to assess the long-term effects of preterm birth on BMD ...
Alwis Gayani - - 2010
We present age- and gender-specific normative bone status data evaluated by quantitative ultrasound (QUS) in the calcaneus with the Lunar Achilles device and compare these estimates with bone mineral content (BMC) and bone mineral density (BMD) estimated by dual X-ray absorptiometry (DXA). Included were a sample of 518 population-based collected ...
Iki M - - 2011
We analyzed 2,107 hip dual-energy X-ray absorptiometry (DXA) images from the Japanese Population-based Osteoporosis Study with the Hip Structure Analysis (HSA) program to obtain age-specific reference values of HSA indices for the Japanese female population. These references may help physicians accurately assess HSA results and aid researchers in making interracial ...
Ko Jung Hee - - 2011
Background/Aims: Much concern has been raised and debated on the effects of obesity and bone mineral density (BMD) after treatment with GnRH agonist. The aim of this study was to assess BMD and body composition, especially percent body fat (%FM) based on dual-energy X-ray absorptiometry (DEXA), before and after 1 ...
Lee Joon Oh - - 2010
To assess age- and site-related bone mineral density (BMD) values in Korean female patients with a distal radius fracture, and to compare them with those of the community-based general Korean female population. For this study, we recruited 54 consecutive Korean women, 50 to 79 years of age, with a distal ...
Bratland-Sanda S - - 2010
To examine (i) aerobic fitness, muscular strength, and bone mineral density (BMD) in female inpatients with longstanding eating disorders and non-clinical controls, and (ii) associated and explanatory factors for BMD among the inpatients. Adult females with DSM-IV anorexia nervosa (AN), bulimia nervosa (BN) or eating disorders not otherwise specified (EDNOS) ...
Jürimäe J - - 2010
The aim of the present study was to investigate changes in ghrelin and bone mineral density (BMD) during further biological maturation after onset of puberty in female adolescent swimmers. Swimmers (n=17) were tested once a year during a two year study period. At the first year, swimmers were at pubertal ...
Berger Claudie - - 2010
We estimated peak bone mass (PBM) in 615 women and 527 men aged 16 to 40 years using longitudinal data from the Canadian Multicentre Osteoporosis Study (CaMos). Individual rates of change were averaged to find the mean rate of change for each baseline age. The age range for PBM was ...
Merchant Rashid - - 2010
To evaluate osteopathy in thalassemia by bone mineral densitometry (BMD) and biochemical indices. Prospective review analysis with no follow up from 2006 to 2007 of 42 regularly transfused thalassemics aged 10-25 years (27 boys, 15 girls) was done. Anthropometry, pubertal stage and symptomatology were noted. Urinary C-terminal cross-linked telopeptide of type-1 ...
Samson F - - 2010
The purpose of this study was to measure the bone mineral density (BMD) of children with Crohn's disease (CD) and to prospectively assess its evolution. A total of 27 children (20 boys, seven girls), aged 12.1±2.5 years, were recruited at the time of CD diagnosis. Dual-energy X-ray absorptiometry (DEXA) was ...
Walsh Conor J - - 2010
To use finite element modeling based on flat-panel volume computed tomography (CT) and bone mineral density (BMD) provided by dual-energy x-ray absorptiometry (DXA) to compare bone failure load, stiffness, and trabecular structure in women with anorexia nervosa (AN) and age-matched normal-weight control subjects. The study was approved by the institutional ...
Bonny Andrea E - - 2011
Since bone loss has been observed among adolescents on depot medroxyprogesterone acetate (DMPA), a clinical population that commonly experiences weight gain, we were interested in examining the direct relationship between body weight and bone mineral density (BMD) in adolescents on DMPA as compared to those on oral contraceptive pills (OC) ...
van der Weijden M A C - - 2011
The objective of this study was to determine the prevalence and risk factors of low bone mineral density (BMD) in patients with spondylarthropathies (SpA) at an early stage of disease. In this cross-sectional study, the BMD of lumbar spine and hips was measured in 130 consecutive early SpA patients. The ...
Cebi Hakan - - 2010
OBJECTIVES: The relation between serum vascular endothelial growth factor (VEGF) level and bone mineral density (BMD) value was evaluated to investigate the role of VEGF at etiopathogenesis of the osteoporosis. PATIENTS AND METHODS: Bone scanning with dual energy X-ray absorptiometry (DEXA) was performed on a total of 276 patients more ...
Kocks J - - 2010
PURPOSE: The diversity of pediatric dual-energy x-ray absorptiometry (DXA) bone mineral density (BMD) reference databases raises questions as to whether they are interchangeable in their application. This study examined the comparability of BMD Z-scores generated from the largest available Hologic DXA databases, applied on BMD results of a large series ...
Kim Sang-Man - - 2010
Uncarboxylated osteocalcin (ucOC) is important in evaluating vitamin K status and it is inversely associated with bone mineral density (BMD). We studied the correlationship between ucOC and BMD in healthy Korean women. This study recruited 337 healthy women between ages 20-70 were recruited. Serum ucOC, calcium, alkaline phosphatase, body mass ...
Abbas J - - 2010
As life expectancy increases, degenerative lumbar spinal stenosis (DLSS) becomes a common health problem among the elderly. DLSS is usually caused by degenerative changes in bony and/or soft tissue elements. The poor correlation between radiological manifestations and the clinical picture emphasizes the fact that more studies are required to determine ...
Abe Y - - 2011
We evaluated the ability of heel quantitative ultrasound (QUS) and metacarpal radiographic absorptiometry (RA) to identify subjects with vertebral deformities in Japanese women aged ≥40. Both QUS and RA were associated with vertebral deformities, and the estimated prevalence at each T-score widely varied with age. Heel QUS and metacarpal RA ...
Tervo Taru - - 2010
The purpose of the present study was to investigate the influence of different types of weight bearing physical activity on bone mineral density (BMD, g/cm(2)) and evaluate any residual benefits after the active sports career. Beginning at 17 years of age, BMD was measured 5 times, during 12 years, in ...
Yoshimura Noriko - - 2011
This prospective cohort study aimed to evaluate the capacity of endogenous sex steroids to predict male osteoporosis (OP) among community-dwelling inhabitants. Among 1,028 male residents aged 40-79 years, 50 men belonging to each age stratum (200 in total) were randomly selected from a resident registration list. In the years 1993, 1996, ...
Sheu Y - - 2011
We compared rates of BMD decline in older men of diverse ethnic background. The rate of bone loss was statistically equivalent between men of African and Caucasian descent. Race differences in peak bone mineral density (BMD) are well established, but the magnitude of bone loss among non-white men has not ...
da Silva Vinicius Zacarias Maldaner - - 2010
The purpose of this study was to assess the respiratory muscle strength (RMS) in individuals with mental retardation (MR), with or without Down Syndrome (DS), and its association with bone mineral density (BMD). Forty-five male individuals (15 with DS, 15 with mental retardation (MR) and 15 apparently healthy controls), aged ...
Wiacek Magdalena - - 2010
In the present study, we analyzed the changes of bone mineral density (BMD) among Polish women age 40-79, as a function of biological aging and body mass index (BMI) class, and compared them with the US sample (National Health and Nutrition Examination Survey III). The null hypothesis of this study ...
Hassan Eskandar - - 2010
STUDY DESIGN: A cross sectional study of thoracic pedicle morphometry in the immature spine of Malaysian population using reformatted computed tomographic (CT) images. OBJECTIVE: To quantify the isthmus endosteal width and height in the thoracic pedicle of the immature spine. SUMMARY OF BACKGROUND DATA: Previous studies of thoracic pedicle morphology ...
Coin Alessandra - - 2010
OBJECTIVE: The aim of this study was to investigate the relationships between nutritional indices (Body mass index (BMI), serum albumin), sarcopenia, bone mineral density (BMD) and the severity of their pulmonary obstruction in elderly patients with chronic obstructive pulmonary disease (COPD). METHODS: The method involved was a prospective transversal study; ...
Zhou Wei - - 2010
The objectives of the study were to develop bone mineral density (BMD) reference norms and BMD Z-scores at various skeletal sites, to determine whether prior fracture and/or asthma were related to BMD, and to assess possible geographic variation of BMD among Canadian youth aged 16-24 yr. Z-Scores were defined as ...
Tong Terry Y Y - - 2010
Apolipoprotein E (ApoE) is implicated in the pathogenesis of osteoporosis. To investigate possible association of the non-classical APOE gene +113C/G (rs440446) intron 1 enhancer polymorphism with bone mineral density (BMD) in a homogeneous Chinese population in Singapore. A total of 655 volunteers, males and females, aged between 31 and 72 ...
Harel Z - - 2010
STUDY OBJECTIVE: To examine vitamin D and parathormone (PTH) levels in adolescents who experienced substantial bone mineral density (BMD) loss during depot medroxyprogesterone acetate (DMPA) use. DESIGN: A non-randomized, multi-center study, during which DMPA was administered every 12 weeks and evaluation of lumbar spine and hip BMD by dual-energy X-ray ...
Ball Chad G - - 2010
A 68 year-old male with a bifid pancreatic neck is described in the context of a common head during pancreatoduodenectomy.
Völgyi Eszter - - 2010
The purpose of this 7-year prospective longitudinal study was to examine whether the level and consistency of leisure-time physical activity (LTPA) during adolescence affected the bone mineral content (BMC) and bone mineral density (BMD) attained at early adulthood. The study subjects were 202 Finnish girls who were 10 to 13 ...
Campion F - - 2010
Professional cycling combines extensive endurance training with non weight-bearing exercise, two factors often associated with lower bone mineral density (BMD). Therefore BMD was measured with dual-energy x-ray absorptiometry in 30 professional road cyclists (mean (SD) age: 29.1 (3.4) years; height: 178.5 (6.7) cm; weight: 71.3 (6.1) kg; %fat mass: 9.7 ...
Ruble Kathy K Department of Oncology and Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA. - - 2010
This study examined the bone mineral density (BMD) of 46 (median age 16.3, 8-29) survivors of autologous and allogeneic bone marrow transplantation (BMT). Areal (g/m2) BMD was acquired with dual energy x-ray absorptiometry and volumetric (g/cm3) BMD values were calculated. Abnormal BMD was identified in 24% (11/46) of survivors with ...
Ohta Hiroaki - - 2010
This study aimed to clarify the relationship between skeletal or lifestyle factors among Japanese daughter-mother, mother-grandmother and daughter-grandmother pairs. We performed a cross-sectional study in a cohort of Japanese adolescent daughters (12-18 years of age), their mothers (339 pairs) and grandmothers on their mothers' side (34 pairs). Gestational age, birth weight, ...
Tan Juay Seng - - 2010
Human cadaveric specimens are commonly used to evaluate bone-implant interface strength in osteoporotic spine fixation. Dual-energy X-ray absorptiometry (DXA) scans are usually carried out on explanted spine specimens to measure bone mineral density (BMD) before in vitro biomechanical studies are carried out. The purposes of this study were to verify ...
Constantini Naama W - - 2010
Studies have shown that physical activity (PA) is superior to many other environmental factors in determining bone mineral density (BMD), but none has examined the independent relationship between PA and vitamin D status. The aim of this study was to assess the relationship among amount of PA, vitamin D (25(OH)D), ...
Zhao Jinhua - - 2010
The purpose of our study was to confirm that forearm bone mineral density (BMD) results obtained with the patient in the supine position are equivalent to results obtained with patient in the sitting position. The subjects were a Chinese sample of 82 healthy adults (35 males and 47 females; age: ...
Multani S K - - 2010
CONTEXT: The erratic lifestyle of resident doctors may affect their serum 25-hydroxy vitamin D [25-(OH)D] levels and bone mineral density (BMD). AIM: To study BMD and the effect of environmental factors on it in resident doctors. SETTINGS AND DESIGN: Prospective, cross-sectional study conducted in a tertiary healthcare centre. MATERIALS AND ...
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