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Fortes Cristina Maria Teixeira CM Clinical and Experimental Pediatrics Research Center, Department of Pediatrics, Botucatu Medical School, Universidade Estadual Paulista (UNESP), São Paulo, SP, - - 2014
to study bone mineral density (BMD) in adolescent females according to five groups of chronological age (CA), bone age (BA), and breast development stage (B), and to correlate these parameters with plasma bone biomarkers (BB). this was a cross-sectional study performed in 101 healthy adolescent females between 10 and 20 ...
Liu Xujie - - 2014
Silver nanoparticles (Ag NPs) have been widely used in bone grafts due to their antimicrobial/antiviral properties. Despite extensive research focused on the cytotoxicity and genotoxicity of Ag NPs, little is known of their effect on cell differentiation. In this study, the uptake of Ag NPs and its effect on the ...
Sohn Elliott H EH Department of Ophthalmology and Visual Sciences, The University of Iowa, Iowa City, Iowa, United States of America ; Stephen A. Wynn Institute for Vision Research, The University of Iowa, Iowa City, Iowa, United States of - - 2014
Structural and gene expression changes in the microvasculature of the human choroid occur during normal aging and age-related macular degeneration (AMD). In this study, we sought to determine the impact of aging and AMD on expression of the endothelial cell glycoprotein CD34. Sections from 58 human donor eyes were categorized ...
Kurtoglu-Aksoy N - - 2014
Premature ovarian failure (POF) is the cessation of ovarian function before the age of 40. The loss of ovarian function, whether premature or not, has an overwhelming impact on female skeletal health, leading to an increased risk of developing osteoporosis because of the lengthened time of exposure to reduced estrogen. ...
Wycislo Kathryn L KL 1University of Illinois, College of Veterinary Medicine, Urbana, IL, - - 2013
Free-roaming cats in New York, NY, USA, that presented to a trap-neuter-return program were surveyed for biochemical data. One hundred and one cats had blood collected for a plasma biochemistry panel after the induction of surgical anesthesia. Reference intervals for 18 analytes were generated for the sample population, along with ...
Yang Cuixia - - 2013
Combined computational and experimental studies reveal a noble, non-d-band effect on Ag activation and electrocatalysis: upon coating Ag onto the even more inert Au surface, the catalytic activity toward the oxygen reduction reaction in alkaline media can be improved by about half an order of magnitude in comparison to the ...
Guang Liang G - - 2013
Cysteine (C)-X-C chemokine receptor-4 (CXCR4) is the primary transmembrane receptor for stromal cell-derived factor-1 (SDF-1). We previously reported in mouse or human bone marrow-derived mesenchymal stromal stem cells (BMSCs) that deleting or antagonizing CXCR4 inhibits bone morphogenetic protein-2 (BMP2)-induced osteogenic differentiation. The goal of this study was to determine whether ...
Cheung Elaine - - 2013
Population-based studies have revealed a decline in the incidence of age-adjusted hip fractures in southern Chinese women during the past decade. To determine whether there was a secular change in population characteristics that accounted for this decline, we compared the bone mineral density (BMD) and lifestyle habits of two cohorts ...
Kyvernitakis Ioannis - - 2013
The aim of this cross-sectional study was to determine the age-dependent variations of calcaneal quantitative ultrasonometry (QUS) and the association with sex hormones and biochemical bone turnover markers in a large sample of unselected healthy German men. Bone measurements are expected to behave differently among men and women. The speed ...
Absolonova Karolina - - 2013
This study describes the estimation of age at death from the compact bone of burned and unburned human ribs. Bone samples came from individuals of known age, sex, and cause of death. Each bone was divided into four sections; three sections were burned at 700, 800, and 1000°C. Undecalcified, unstained ...
Lucarini Nazzareno - - 2012
Acid phosphatase (ACP₁) is a polymorphic enzyme that catalyzes the conversion of flavin-mononucleotide (FMN) to riboflavin and regulates the cellular concentration of flavin-adenine-dinucleotide (FAD) and, consequently, energy metabolism. Its activity is modulated by adenosine deaminase locus 1 (ADA₁) genotype. The aim of our work is to verify whether individuals with ...
Fischer Dagmar-Christiane - - 2012
BACKGROUND: Paediatric reference values for novel markers of phosphate homeostasis, bone formation and resorption and their putative relationship to growth are lacking. METHODS: A total of 424 healthy children, adolescents and young adults (221 males) aged 0.1-21 y, were enrolled in this cross-sectional study. Height, weight and height velocity were ...
Lin Cheng-Yung CY Graduate Institute of Animal Science, National Chung Hsing University, Taichung, Taiwan - - 2012
An experiment was carried out to determine the effect of age and caponization on the development blood and bone characteristics development in male country chickens in Taiwan. A total of two hundred 8-wk-old LRI native chicken cockerels, Taishi meat No.13 from LRI-COA, were used as experimental animals. Cockerels were surgically ...
Yu Bin - - 2012
Efficacy of recombinant adenovirus serotype 5 (rAd5) vaccine vectors for human immunodeficiency virus type 1 (HIV-1) and other pathogens have been shown to be limited by high titers of pre-existing Ad5 neutralizing antibodies (NAbs) in the developing world. Using a secreted embryonic alkaline phosphatase (SEAP) neutralization assay, 50% serum neutralization ...
Kumar Pardeep - - 2011
Biological aging is a fundamental process observed in almost all living beings. During aging the brain experiences structural, molecular, and functional alterations. Aging in females and males is considered as the end of natural protection against age related diseases like osteoporosis, coronary heart disease, diabetes, Alzheimer's and Parkinson's disease. These ...
Roach James W - - 2011
Patients with spina bifida potentially experience social isolation with limited employment opportunities and restriction of independent living, neurologic and intellectual impairment, and orthopaedic and urologic consequences of their condition. However, the degree of disability as these individuals age into adulthood has not been completely delineated. In adults with spina bifida ...
Hermann Derik - - 2011
Pre-clinical research indicates that opioids reduce extracellular glutamate in acute opioid treatment, whereas during withdrawal, glutamatergic neurotransmission is increased and withdrawal symptoms can be blocked by glutamate receptor antagonists. The glutamate hypothesis of addiction suggests that withdrawal-associated hyperglutamatergic states destabilize the glutamatergic system chronically and contribute to relapse. magnetic resonance ...
Lindsay Sally - - 2011
Purpose. Despite the importance of ensuring access to assistive technology, high rates of underutilization remain. Relatively little is known about the characteristics of young people reporting unmet needs for assistive devices, so our study examined this further. Method. Data were analyzed using the 2006 Participation and Activity Limitation Survey. Youth aged 15-24 ...
Aratani Mayra Cristina - - 2011
To analyze the hierarchical structure of activities of daily living (ADL) among vestibular older adults, according to its power to discriminate disability. An exploratory cross-sectional study was conducted comprising 235 elderly, aged 65 years and older, with chronic vestibular dysfunction. Functional capacity was assessed through the Brazilian version of OARS ...
Kumar Pardeep - - 2011
Free radical production and oxidative stress are known to increase in liver during aging, and may contribute to the oxidative damage. These changes increase during menopausal condition in females when the level of estradiol is decreased. The objective of this study was to observe the changes in activities of membrane ...
- - 2010
We are modifying our regulations to establish a 12-month time limit for the withdrawal of old-age benefits applications, allow one withdrawal per lifetime, and limit the voluntary suspension of benefits for purposes of receiving delayed retirement credits to months for which you have not received a payment. We are making ...
Goins R Turner - - 2010
Comorbidity is a growing challenge and the older adult population is most at risk of developing comorbid conditions. Comorbidity is associated with increased risk of mortality, increased hospitalizations, increased doctor visits, increased prescription medications, nursing home placement, poorer mental health, and physical disability. American Indians experience some of the highest ...
Lindsay Sally - - 2011
Purpose. Having a disability is a barrier to securing and maintaining employment. Most research has focussed on employment barriers among adults, while very little is known about young people's experience finding paid work. Method. Young people aged 15-24 were selected from the 2006 Participation and Activity Limitation Survey to explore the barriers ...
Milaneschi Yuri - - 2010
In many countries, persons over 65 are one of the fastest growing segments of the population. Mobility disability is one of the major risk factors for morbidity and mortality in this age group. There is increasing evidence that improved nutrition can reduce the risk of developing disability in older age. ...
Vela Luzita I - - 2010
Disablement theory has been characterized as the sequence of events that occurs after an injury, but little research has been conducted to establish how disablement is experienced and described by physically active persons. To describe the disablement process in physically active persons with musculoskeletal injuries. Concurrent, embedded mixed-methods study. For ...
Plantinga Laura C - - 2011
Little is known about disability in early-stage chronic kidney disease (CKD). Cross-sectional national survey (National Health and Nutrition Examination Survey 1999-2006). Community-based survey of 16,011 noninstitutionalized US civilian adults (aged ≥20 years). CKD, categorized as no CKD, stages 1 and 2 (albuminuria and estimated glomerular filtration rate [eGFR] ≥60 mL/min/1.73 ...
Vanvuchelen M - - 2011
The teaching of imitation skills is often the first step in interventions for young learners with intellectual disabilities. The main goal of this study was to determine the smallest detectable difference (SDD) at 95% confidence of the Preschool Imitation and Praxis Scale (PIPS) in preschoolers with intellectual disabilities. Two raters ...
La Grow Steven - - 2011
The purpose of this paper was to determine the extent to which factors thought to be related to quality of life (QoL) among older persons with a visual disability impact on their perceived QoL (PQol). Analysis was conducted on responses from the second wave of a large population-based longitudinal study ...
Wong Rebeca - - 2010
To examine the old-age consequences of international migration with a focus on disability and wealth from the perspective of the origin country. Analysis sample includes persons aged 60+ from the Mexican Health and Aging Study, a national survey of older adults in Mexico in 2001. Univariate methods are used to ...
Griffith Lauren - - 2010
to investigate the population impact on functional disability of chronic conditions individually and in combination. data from 9,008 community-dwelling individuals aged 65 and older from the Canadian Study of Health and Aging (CSHA) were used to estimate the population attributable risk (PAR) for chronic conditions after adjusting for confounding variables. ...
Rejeski W J WJ Departments of Health and Exercise Science and Geriatric Medicine, Wake Forest University School of Medicine, Wake Forest University, Winston-Salem, NC, - - 2010
We examine obesity, intentional weight loss and physical disability in older adults. Based on prospective epidemiological studies, body mass index exhibits a curvilinear relationship with physical disability; there appears to be some protective effect associated with older adults being overweight. Whereas the greatest risk for physical disability occurs in older ...
Lindsay Sally - - 2011
Purpose. Little is known about the work experiences of youth as they transition to adulthood. The purpose of this study is to explore the characteristics associated with disabled youth who are employed and the types of employment they are engaged in. Method.  Data were analysed using the 2006 Participation and Activity ...
Chiu Ching-Ju - - 2011
This research combined cross-sectional and longitudinal data to characterize age-related trajectories in physical disability for adults with and without diabetes in the United States and to investigate if those patterns differ by age, gender, race or ethnicity, and education. Data were examined on 20,433 adults aged 51 and older from ...
Chou Yueh-Ching - - 2011
ABSTRACTBackground: Informal, unpaid, and lifelong older caregivers of adults with intellectual disabilities (ID) are usually female and most often are mothers of adults with ID. However, research exploring different predictors of subjective and objective burden among these older female caregivers is sparse. The objective of this study was to examine ...
Katzenellenbogen Judith M - - 2010
BACKGROUND: The disability-adjusted life year index is used extensively to compare disease burden among diseases and locations, but difficulties remain in accurately estimating the nonfatal stroke burden in years lived with disability. AIMS: To improve stroke-related years lived with disability estimates in Western Australia for 2000, by improving the accuracy ...
Zanni Guido R - - 2010
Aging is associated with physical decline, often accompanied by pathology and disability that can cause unhappiness and dissatisfaction. Despite this, many elders report a high level of satisfaction. This article discusses the anxiety associated with aging that some people experience, highlights research findings and models of aging, and pays particular ...
Polidoro A - - 2011
Decreased reserves in multiple organ systems identify frailty syndrome in the elderly. However, its clinical diagnostic approach may be hard, particularly in patients with chronic diseases. The purpose of the study was to delineate the role of disability in the frailty syndrome in a group of hospitalized elderly people. A ...
Kuppens Sofie - - 2010
The Supports Intensity Scale (SIS) was developed to provide information on the support needs of persons with intellectual disability. Our aim here was to evaluate the factorial validity of the SIS in a sample of 14,862 persons with intellectual disability. The structure of the instrument as promulgated by the developers ...
Jenkins Robert - - 2010
This article discusses the author's use of reflexivity in trying to gain a better understanding of ageing in older people with learning disabilities. In the general population ageing is viewed in rather negative terms and as a significant life transition. However, for some older people with learning disabilities this transition ...
Weir Patricia L - - 2010
Rowe and Kahn's (1987, 1998) model of successful aging (SA) implies a balance among: (1) low probability of disease and disease-related disability; (2) high cognitive and physical functioning; and (3) active engagement with life. This study assessed the relationship of age to the components of SA across the sixth, seventh ...
Hunt Kate K MRC Social and Public Health Sciences Unit, University of Glasgow, 4 Lilybank Gardens, Glasgow, Scotland G12 8RZ, United Kingdom. - - 2010
This study was to examine whether overall physical activity levels, and different types of earlier sporting activities, are associated with the onset of locomotor disability in early older age. A longitudinal analysis of a general population cohort of British men and women born in the early 1930s was conducted. Measures ...
Fitzmaurice Christina - - 2011
Health promotion and disease prevention among people with disabilities are often overlooked. The objective of this article is to determine if working age adults with disabilities differ in healthy behaviours from those without disabilities. Behavioural Risk Factor Surveillance System data (2003) were used to assess healthy behaviours among 201,840 community ...
Dyreborg Johnny - - 2010
The aim of this study was to evaluate the incidence of disability pension among workers engaged in the construction of the Øresund Link or the Copenhagen Metro, representing high levels of safety management. The study subjects (n = 1,808) were followed for disability retirement. Age standardized incidence ratios (SIRs) were ...
Patti P - - 2010
BACKGROUND: Aging adults with Down's syndrome (DS) experience more relocations and other life events than adults with intellectual disabilities aged 50 and older without DS. Age-related functional decline and the higher incidence of dementia were implicated as the contributing factors that led to relocation and nursing home placement. METHOD: A ...
Liang Jersey - - 2010
Current findings on gender and age differences in health trajectories in later life are equivocal and largely based upon data derived from Western developed nations. This study examines gender and age variations in the trajectory of functional status among older adults in Taiwan, a non-Western newly industrialized society. Data came ...
Al Snih Soham S Sealy Center on Aging, University of Texas Medical Branch, Galveston, TX 77555-0460, USA. - - 2010
The prevalence and incidence of both obesity and disability are projected to increase in the coming decades. The authors examined the relation between obesity and disability in older adults from 6 Latin American cities participating in the Health, Well-Being and Aging in Latin America and the Caribbean (SABE) Study (1999-2000). ...
Strax Thomas E - - 2010
This article addresses the challenges faced by individuals with a developmental disability as they age. As this group ages, many face unpleasant experiences including poverty, isolation, abuse, and at best adequate, but more commonly poor medical care. Due to biomechanical overuse, compounded by an injured nervous system, physiologic aging is ...
Motl Robert W - - 2010
This article provides an overview of physical activity and its association with function, disability, and quality of life (QOL) outcomes among older adults. The rationale and the associated onset of chronic disease conditions that influence function, disability, and QOL is embedded in the "Graying of America". The literature reviewed in ...
Finlayson Marcia L - - 2010
Falls are a major public health problem, contributing to significant morbidity and mortality among older adults in the United States. This article summarizes and compares (1) fall prevalence rates, (2) fall risk factors, (3) consequences of falls, and (4) current knowledge about fall prevention interventions between community-dwelling older adults and ...
Johnson Kurt L - - 2010
Aging with disabilities, such as multiple sclerosis, spinal cord injury, muscular dystrophy, and postpolio syndrome, can lead to barriers to participation, including employment barriers. Many individuals develop strategies for overcoming these barriers that may become less successful as they experience more secondary conditions concomitant with the aging process. Rehabilitation professionals ...
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