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Guo Xiaoxiao X Department of Cardiology, Peking Union Medical College Hospital, Peking Union Medical College & Chinese Academy of Medical Sciences, Beijing, - - 2014
Advanced age is a well-recognized predisposition to atrial fibrillation (AF). However, the cellular electrophysiological changes that underlie the heightened susceptibility to AF in aged individuals remain poorly understood. Sarcoplasmic reticulum (SR) Ca(2+) leak that results from posttranslational modification of type 2 ryanodine receptor channels (RyR2) has been implicated in arrhythmogenesis. ...
Stephan Jessica - - 2013
The discovery that genetic mutations in several cellular pathways can increase lifespan has lent support to the notion that pharmacological inhibition of aging pathways can be used to extend lifespan and to slow the onset of age-related diseases. However, so far, only few compounds with such activities have been described. ...
Zhang Wei - - 2013
OBJECTIVE: To investigate whether the ultrastructure and H+ -K+ -ATPase expression of human parietal cells are associated with age-related alterations. METHODS: Fifty partipants who underwent gastroscopy due to dyspepsia were enrolled and divided into two age groups, with 19 in the younger group (YG, age 20-59 years) and 31 in ...
Rockman Caron B - - 2012
OBJECTIVE: Certain races are known to be at increased risk for stroke, and the prevalence of carotid artery stenosis (CAS) is thought to vary by race. The goal of this report was to study the prevalence of CAS in different races by analyzing a population of subjects who underwent vascular ...
Schouten Henrike J - - 2012
To determine whether the use of age adapted D-dimer cut-off values can be translated to primary care patients who are suspected of deep vein thrombosis. Retrospective, cross sectional diagnostic study. 110 primary care doctors affiliated with three hospitals in the Netherlands. 1374 consecutive patients (936 (68.1%) aged >50 years) with ...
Estrela Fabiana - - 2011
This prospective study investigated the anatomic relations between the external branch of the superior laryngeal nerve (EBSLN), the superior thyroid artery (STA) and the thyroid gland in human cadavers. Twenty-two human cadavers aged over 18 years old, less than 24 hours after death. The mean distance between the EBSLN and ...
Weinberger M - - 2011
Clin Microbiol Infect 2011; 17: 278-284 ABSTRACT: Among bacterial foodborne pathogens, non-typhoid Salmonella enterica (NTS) is a leading cause of death worldwide. This study assessed short-term and long-term mortality following NTS infection in Israel, and evaluated the effects of age, sex, source of isolation and different serotypes on mortality. The ...
Nasrullah Muazzam - - 2011
Drowning is the fifth leading cause of unintentional fatalities in the US. Our study described demographics and trend analysis of unintentional drowning mortality in the US from 1999 to 2006, and identifies the changes in deaths for specific population subgroups. Mortality data came from the CDC's Web-based Injury Statistics Query ...
Bubenik G A - - 2011
Human life span, with or without modern medicine is around 85-95 years. All living creatures have their inner clock that measures their daily (circadian) and their seasonal (circannual) time. These time changes are mediated by the alteration of levels of melatonin, an evolutionary ancient hormone, which is produced in many ...
Ugarte María D - - 2010
In recent decades, a decline in breast cancer mortality has been observed across Europe, and also in Spain. Our objective is to assess the spatio-temporal pattern during the period 1975-2005 by specific age groups (<45, 45-64, ≥65) in the Spanish provinces. For each age group, a spatio-temporal P-spline model with ...
Doi Yuriko - - 2010
The present study examined temporal trends and geographic clustering of amyotrophic lateral sclerosis (ALS) mortality in Japan, during 1995-2004, using vital statistics based on death certificates. ALS was usually diagnosed by neurologists according to clinical guidelines that complied with the El Escorial Criteria. The underlying cause of death for ALS ...
Cohen Cheryl - - 2010
Although essential to guide control measures, published estimates of influenza-related seasonal mortality for low- and middle-income countries are few. We aimed to compare influenza-related mortality among individuals aged ≥65 years in South Africa and the United States. We estimated influenza-related excess mortality due to all causes, pneumonia and influenza, and ...
Baird Lissa C - - 2010
The majority of boxing-related fatalities result from traumatic brain injury. Biomechanical forces in boxing result in rotational acceleration with resultant subdural hematoma and diffuse axonal injury. Given the inherent risk and the ongoing criticism boxing has received, we evaluated mortalities associated with professional boxing. We used the Velaquez Fatality Collection ...
Sligl Wendy I - - 2010
OBJECTIVE: To determine the association between age and mortality in critically ill patients with pneumonia. We hypothesized that increasing age would be independently associated with both short- and long-term mortality. DESIGN: Prospective population-based cohort study examining the association between age and 30-day (short-term) and 1-yr (long-term) mortality using Cox proportional ...
Kapranas Apostolos - - 2011
1. Sex ratio theory predicts that developmental mortality can affect sex ratio optima under Local Mate Competition and also lead to 'virgin' broods containing only females with no sibling-mating opportunities on maturity. 2. Estimates of developmental mortality and its sex ratio effects have been laboratory based, and both models and laboratory studies ...
Petersen Line Kirkeby - - 2010
People aged 80 or older are the fastest growing population in high-income countries. One of the most common causes of death among the elderly is the cardiovascular disease (CVD). Lipid-lowering treatment is common, e.g. one-third of 75-84-year-old Swedes are treated with statins. The assumption that hypercholesterolaemia is a risk factor ...
Neligan A - - 2011
to determine how the duration of SE, the EEG findings during/after SE, the depth of coma at presentation and age impact on the prognosis of convulsive status epilepticus indepedent of aetiology and to analyse the outcome of status epilepticus with respect to mortality and morbidity (the latter measured in terms ...
Fernández-Ballesteros Rocío - - 2011
Attrition is one of the most important threats for longitudinal studies on aging mainly due to refusal and mortality. This study deals with those individuals who were assessed in the base line of 90+ project but died, dropped out or were examined in the follow-up. Participants of the 90+ project ...
Angel Ronald J - - 2010
OBJECTIVE: In this article, the authors investigate the association between age at migration and mortality during a 13-year period in a sample of Mexican American immigrants aged 65 and older at baseline. METHODS: The authors use the Hispanic Established Populations for Epidemiologic Studies of the Elderly (H-EPESE) to control for ...
Hajat Anjum - - 2010
To examine all-cause mortality differentials among New Zealand's (NZ) immigrant population. Unlike other studies that use the total non-migrant population as the reference group, we use NZ-born populations of the same ethnic group for comparison purposes. Our study intends to answer two questions: first, do immigrants have a mortality advantage ...
Houben Joyce M J - - 2011
Telomere shortening is a marker of aging and therefore telomere length might be related to disease progression and survival. To address these questions, we measured leukocyte telomere length (LTL) in male participants from the Zutphen Elderly Study. LTL was measured by quantitative polymerase chain reaction in 203 men: mean aged ...
Holvik Kristin - - 2010
To identify to which degree patient-related factors (age, gender, place of residence, general health condition, comorbidity) and hospital-related factors (waiting time for surgery, type of surgery, in-hospital complications, length of stay) may predict 1-year mortality in elderly hip fracture patients in an orthogeriatric unit, to optimize treatment and care. In-hospital ...
Panapasa Sela V SV Institute for Social Research, University of Michigan, Ann Arbor, MI 48106, USA. - - 2010
We examined mortality patterns across the lifespan of Native Hawaiians and compared mortality disparities across races. We determined the age-specific and age-adjusted mortality rates of Native Hawaiians from 1990 to 2000 by using national census and vital registration data. Among Native Hawaiians aged younger than 1 year, expected deaths were ...
Bhala Neeraj - - 2010
Deaths caused by alcohol have increased in the UK, and Scotland in particular, but the change in the rates of alcohol-related deaths for migrants are uncertain, and could yield insights for the general population. Alcohol-related mortality in immigrants among Scotland's residents was assessed using 2001 census data and mortality data ...
Jolly Stacey - - 2010
Blacks have higher rates of cardiovascular disease than whites. The age at which these differential rates emerge has not been fully examined. We examined cardiovascular disease prevalence and mortality among black and white adults across the adult age spectrum and explored potential mediators of these differential disease prevalence rates. We ...
Saadoun D - - 2010
OBJECTIVE: To report the long-term mortality in patients with Behçet's disease (BD). METHODS: A cohort of 817 patients fulfilling the international criteria for BD from a single center in France were analyzed for causes of death, the standardized mortality ratio (SMR), and the factors associated with mortality. RESULTS: Among the ...
Odton Patarapan - - 2010
In this study, we examined age-specific death rates among men and women from various districts in Thailand using mortality data from 1999 to 2001. A Poisson generalized linear model was used for analysis. To adjust for large variations in resident populations among districts, the 926 districts in Thailand were reduced ...
Couto Arnaldo Cézar - - 2010
To analyze trends in childhood leukemia mortality in the state of Rio de Janeiro, Brazil, between 1980 and 2006. Gender-stratified leukemia mortality data for children aged < 15 years from 1980 to 2006 were retrieved from the Brazilian Mortality Information System for the state of Rio de Janeiro. Data were ...
Escames Germaine - - 2010
Melatonin is an endogenous indoleamine present in different tissues, cellular compartments and organelles including mitochondria. When melatonin is administered orally, it is readily available to the brain where it counteracts different processes that occur during aging and age-related neurodegenerative disorders. These aging processes include oxidative stress and oxidative damage, chronic ...
Tsuboi Masaki - - 2011
There are several reports from Europe and the United States on mortality from musculoskeletal degenerative diseases; however, no reports have been published from Japan. This study is the first that has examined whether musculoskeletal degenerative diseases affect life prognosis in Japan. As many as 944 persons who were 60 years of ...
Chowell Gerardo - - 2010
Although the mortality burden of the devastating 1918 influenza pandemic has been carefully quantified in the United States, Japan, and European countries, little is known about the pandemic experience elsewhere. Here, we compiled extensive archival records to quantify the pandemic mortality patterns in 2 Mexican cities, Mexico City and Toluca. ...
Tan Lavinia - - 2010
AIM: To provide an update for the assessment of discrepancies in ethnicity counts in the 2001 census and mortality data for the 2004-2006 period. METHODS: 2001 census anonymously and probabilistically linked to 5 years of subsequent mortality data (135,849 eligible mortality records), allowing a comparison of ethnicity recording for the ...
Baird Lissa C - - 2010
The majority of boxing-related fatalities result from traumatic brain injury. Biomechanical forces in boxing result in rotational acceleration with resultant subdural hematoma and diffuse axonal injury. Given the inherent risk and the ongoing criticism boxing has received, we evaluated mortalities associated with professional boxing. We used the Velazquez Fatality Collection ...
Leander Mai - - 2010
BACKGROUND: Asthma is a common chronic health condition among the elderly and an important cause of morbidity and mortality. Some studies show that subjective assessments of health-related quality of life (HRQL) are important predictors of mortality and survival. The primary aim of this study was to investigate whether low HRQL ...
Mohr Alicia M - - 2010
Gender differences in the physiological response to trauma can affect outcome. Both hyperglycemia and blood glucose (BG) variability predict a poor outcome after trauma. This study examined the hypothesis that both BG levels and the degree of BG variability after trauma are gender-specific and correlate with mortality and morbidity. A ...
Testa Gianluca - - 2010
OBJECTIVES: To examine whether waist circumference (WC) and body-mass index (BMI) can predict long-term mortality in elderly subjects with and without chronic heart failure (CHF). DESIGN: Longitudinal evaluation with a 12-year follow-up. SETTING: Campania, a region of southern Italy. PARTICIPANTS: One thousand three hundred thirty-two subjects aged 65 and older ...
Takata Yutaka - - 2011
The equation for Japanese estimated glomerular filtration rate (eGFR) was revised by measuring GFR by inulin clearance. The association of the new eGFR with all-cause mortality and mortality from cardiovascular disease (CVD) was assessed in an elderly Japanese population. Seventy-year-old subjects, residents of Niigata, Japan, participated. Baseline examinations were carried ...
Brosselin P - - 2010
Alzheimer's and related diseases have become a major public health issue in all developed countries, particularly with the aging of the population. Given the potential burden of these pathologies, the French government launched a third National Alzheimer's Strategic Plan 2008-2012 in 2008. The aim of the study was to provide ...
Kizer Jorge R - - 2010
Cross-sectional studies show that adiponectin is higher in older than in younger adults but long-term change in adiponectin, its determinants, and its relationship to functional decline or survival in the elderly population have not been evaluated. We investigated predictors of longitudinal change in adiponectin, and the association of this adipokine ...
Souza D C C - - 2010
To estimate mortality rates and mortality trends from SLE in the state of São Paulo, Brazil. The official data bank was used to study all deaths occurred from 1985 to 2004 in which SLE was mentioned as the underlying cause of death. Besides the overall mortality rate, the annual gender- ...
Gedeborg Rolf - - 2010
To assess whether higher mortality rates among individuals in motor vehicle crashes in areas with low population density depend on injury type and severity or are related to the performance of emergency medical services (EMS). Prehospital and hospital deaths were studied in a population-based cohort of 41,243 motor vehicle crashes ...
Sherratt T N - - 2010
1. Age-dependent increases in mortality have been documented in a variety of species of insect under laboratory conditions. However, while strong statistical evidence has been presented for senescence in vertebrate populations in the wild, we know little about the rate and shape of senescence in wild populations of insects. 2. ...
Iranipour S - - 2011
Life table studies of sunn pest were carried out in Varamin, Iran, from 1998-2001 in order to determine stage-specific mortalities and the impact of specific natural enemies on population dynamics. Populations were sampled 2-3 times weekly in agricultural fields during the growing season and monthly during the period of dormancy ...
Coggon David D MRC Epidemiology Resource Centre, University of Southampton, Southampton, UK. - - 2010
To explore time trends in deaths attributable to work in England and Wales, and identify priorities for prevention, we conducted a proportional analysis of mortality by occupation over a 22-year period. Analysis was based on deaths in men aged 20-74 years during 1979-1980 and 1982-2000 with a recorded occupation. Proportional ...
Skinner Holly J - - 2010
Epidemiologic data on convulsive status epilepticus (CSE) is needed to develop preventative strategies. Epilepsy is one of the known risk factors for CSE. A systematic review of epidemiologic studies on status epilepticus (SE) completed in the United States and Europe reports that people with epilepsy account for less than 50% ...
Gitau George K - - 2010
The study reported data from 507 post-mortem records in the Department of Pathology, Microbiology and Parasitology, Faculty of Veterinary Medicine, University of Nairobi, Kenya. The records were from carcasses obtained from the peri-urban area of Nairobi during a 20-year period between 1990 and 2009. Approximately 80% (393/507) of the calf ...
Thach Thuan-Quoc - - 2010
Visibility in Hong Kong has deteriorated significantly over 40 years with visibility below 8km in the absence of fog, mist, or precipitation, increasing from 6.6 days in 1968 to 54.1 days in 2007. We assessed the short-term mortality effects of daily loss of visibility. During 1996-2006, we obtained mortality data ...
Keyes Katherine M KM Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY 10032, USA. - - 2010
Understanding the effects of age, period, and cohort on disease morbidity and mortality may help identify etiological factors and inform prevention programs. We illustrate a three-phase method that conceptualizes the cohort effect as a partial interaction between age and period. As an example of application, we analyze homicide mortality data ...
Martínez-Muñoz Marco A - - 2010
Longfin sanddab (Citharichthys xanthostigma) represents a very important fishery resource in Southern and Baja California but are not very well known. The purpose of this study is to provide information on the growth and mortality of longfin sanddab population in the Mexican Pacific Ocean at Baja California, México. Data on ...
Infurna Frank J - - 2010
Self-reflections of age and aging are predictors for key outcomes such as mortality, but little is known about the nature and potential antecedents of subjective age in very old age. We used cross-sectional data from the Swedish OCTO study (N = 267; B. Johansson & S. H. Zarit, 1995) and ...
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