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- - 2014
Members of the nonbiting midge family Chironomidae have been used worldwide as water-quality indicators or toxicity test organisms. The purpose of this study was to establish the chironomid Glyptotendipes tokunagai Sasa as a new test species by conducting successive rearing under laboratory conditions. We monitored biological and genetic aspects of ...
Zartler Edward R ER Quantum Tessera Consulting , Collegeville, Pennsylvania 19426, United - - 2014
Fragonomics is the process of using small, relatively simple molecules to generate chemical starting points for hit generation. Fragonomics has come of age and is now one of the major concepts in hit generation. What is its future?
Waring Avantika C - - 2012
Data on thyroid function in the oldest old are sparse, and existing studies show conflicting evidence on the relationship between thyroid function and mortality in this age group. We describe longitudinal changes in thyroid function in a cohort of elderly individuals and determine the relationship between thyroid function and mortality. ...
Tognini Sara - - 2012
Background Conflicting data are reported on the association between mild thyroid failure and lipid profile, primarily regarding serum triglyceride values and patients with slightly elevated TSH (<10 mIU/l). In this study, we assessed the possible influence of gender and age on this relationship. Methods The study included 2308 consecutive patients ...
Corona G G Department of Clinical Physiopathology, Sexual Medicine and Andrology Unit, University of Florence, Florence, - - 2012
The role of thyroid hormones in the control of erectile functioning has been only superficially investigated. The aim of the present study was to investigate the association between thyroid and erectile function in two different cohorts of subjects. The first one derives from the European Male Ageing Study (EMAS study), ...
McNally Richard J Q - - 2012
Increases in the incidence of thyroid cancer have been previously reported. The purpose of the present study was to examine temporal trends in the incidence of primary thyroid cancer diagnosed in 0-49 year olds in parts of Great Britain during 1976-2005. Data on 4,337 cases of thyroid cancer were obtained from ...
Sen B - - 2012
Thyroid disorders are frequent in elderly population and difficult to recognize because of their atypical presentation, and the absence of classic signs and symptoms. Nonspecific symptoms, even in the absence of thyroid dysfunction, are common in this age group, including fatigue, anorexia, weight loss, failure to rehabilitate, and difficult to ...
Ajish T P - - 2012
Thyroid anatomy and physiology change in the elderly with age-related fibrosis and atrophy in the thyroid gland and changes in thyroid hormones. The incidence of thyroid nodules increases with age, making the thyroid more nodular. Hypothyroidism is common in the elderly and, if untreated, is associated with significant morbidity. Elderly ...
Kahapola-Arachchige Kalani M - - 2012
OBJECTIVE: The use of age-specific reference ranges for TSH is advocated, but the impact of this on laboratory diagnosis of thyroid dysfunction is unclear. Our aims were to determine age-specific TSH reference ranges and to examine inter-assay differences in performance. DESIGN: We analysed TSH results from 223,045 consecutive samples assayed ...
Kirmızibekmez Heves - - 2012
Developmental defects of the thyroid gland are the most frequent causes of permanent congenital hypothyroidism. This study aimed to investigate the epidemiological features of patients with thyroid dysgenesis (TD). Medical records of 234 patients with TD followed between the years 2008 and 2010 were evaluated retrospectively. Diagnosis was made by ...
Charlier Philippe - - 2012
Disturbances in some endocrine hormones have been implicated in the pathophysiology of depression and psychosis. We consider here further the hypothesis that there may be a correlation between suicide risk and the weight of the thyroid gland. The thyroid weight and other relevant information (sex, BMI) were collected retrospectively from ...
Chiang Wen-Fang - - 2012
BACKGROUND: Profound hypokalemia with paralysis usually poses a diagnostic and therapeutic challenge. METHODS: We report on a 28-y-old obese Chinese female presenting with sudden onset of flaccid quadriparesis upon awaking in the morning. There is no family history of hyperthyroidism. She experienced body weight loss of 7kg in 2months. RESULTS: ...
Nurunnabi A S M - - 2012
The present study was designed to find out the difference in volume of the thyroid gland of Bangladeshi people in relation to age and sex and to compare with previous local and foreign studies. It was a Cross-sectional descriptive type of study. The hospital based study was conducted in the ...
Oyer Samuel L - - 2012
Objective. To determine the impact of age on disease-specific survival in differentiated thyroid cancer.Study Design. Retrospective analysis of a large population database.Setting. Surveillance, Epidemiology, and End Results (SEER) database/multiple settings.Subjects and Methods. The SEER database was examined to identify patients diagnosed with either papillary or follicular carcinoma of the thyroid ...
Somwaru Lily L LL Division of Endocrinology, Diabetes, and Metabolism, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104-5160, - - 2012
Studies of long-term outcomes of subclinical hypothyroidism have assessed only baseline thyroid function, despite natural transitions to euthyroidism and overt hypothyroidism over time. We provide estimates of persistence, resolution, and progression of subclinical hypothyroidism over 4 yr, stratified by baseline TSH, anti-thyroid peroxidase antibody (TPOAb) status, age, and sex. Participants ...
Santaniello B - - 2012
The aim of this study was to assess the prevalence of non toxic goiter, difuse or nodular, in all Genoa's Country thyroid diseases. The authors have studied one non-random casuistry of 1980 Patients observed from time to time in the last decade in Ambulatory of Nuclear Medicine (Department of Internal ...
Bremner Alexandra P - - 2012
Context:In cross-sectional studies, serum TSH concentrations increase with age. This has not been examined longitudinally, and it is uncertain whether the TSH increase reflects healthy aging or occult thyroid failure.Methods:We measured serum TSH, free T(4), thyroid peroxidase, and thyroglobulin antibodies in 1100 participants in the 1981 and 1994 Busselton Health ...
Chen Guoqiang - - 2012
IgG functions rely on interactions of the Fc region with other proteins, which are optimized by tailoring of a conserved N-linked glycosylation at Asn-297. We conducted a study involving 735 control individuals and 138 thyroid cancer patients. Here we demonstrated that previously described age-related change in Fc-glycosylation was further characterized ...
Sayyahfar Shirin - - 2012
Thyroid abscess is a rare event especially in the pediatric age group. We report a 2-year-old girl with thyroid abscess who presented with fever and an anterior painful neck mass. Culture of the aspirated fluid yielded Arcanobacterium haemolyticum, which is one of the etiologies of pharyngitis and rash in children ...
Kim Bu Kyung - - 2012
Iodine deficiency is defined by the goiter and the urinary iodine concentration. However, a lack of local thyroid volume reference data resulted in the vague definition of goiter, especially in school-aged children. The aim of this paper was to determine the thyroid volumes by ultrasonography in schoolchildren aged 6 to ...
Holmes Laurens L - - 2012
Pediatric thyroid carcinoma is relatively uncommon. But variability in incidence rate by race, sex, age at onset/diagnosis, and geographic local had been observed in adult thyroid carcinoma in the USA. We aimed to examine the patterns, rates, and temporal trends of thyroid carcinoma among pediatric patients (0-19 years) between 1973 ...
Shivaprasad H S - - 2012
The main objective of this study is to find out the genetic variation and predisposition of overweight/obese, smoking/alcoholism and thyroid disease traits among tasters and non-tasters in Mysore population, South India. Bitter-taste perception for phenylthiocarbamide (PTC) is a classically variable trait both within and between human populations. Many studies have ...
Abunassar Michael J - - 2012
Smoking remains the most common preventable cause of death. Very little tobacco exposure can increase cardiovascular disease risk. The relationship between smoking, sex, and weight remains unclear. Between September 1992 and June 2007, 2582 consenting patients starting the Ottawa Hospital Weight Management program were grouped by sex and smoking status. ...
Przybylik-Mazurek Elwira E Department of Endocrinology, Jagiellonian University Medical College, ul. Kopernika 17, Kraków, - - 2012
Nutritional factors are known to be important in the development of different metabolic diseases. The history of nodular or diffuse goiter is closely related to risk of thyroid carcinoma. On account of the function of the thyroid gland, many studies focus on iodine intake. The aim of the study was ...
Mollee Terezka S - - 2011
There is some evidence for elevated thyrotropin (TSH) levels in children born preterm, but follow-up studies into adulthood are lacking. We tested whether thyroid function in young adults born at a gestational age < 32 weeks, with either an appropriate (appropriate for gestational age, AGA) or low birth weight for ...
Bedford Olwen - - 2011
This study explores the role of the hostess club culture in the creation and maintenance of masculinity in Taiwan. The article focuses on flower drinking (the consumption of alcohol in bars, often integrated with prostitution), which is a common practice in Taiwan. Data were obtained from 58 in-depth interviews with ...
Rose Abigail Katherine AK Division of Psychological Medicine and Psychiatry, Section of Alcohol Research, National Addiction Centre, Institute of Psychiatry, King's College London, London, - - 2010
The objective of this study was to compare alcohol urge, drinking behaviour and mood across two beverage conditions (alcohol/soft drink), over multiple drinks. Forty-five (22 men) participants completed two conditions (alcohol/soft-drink). Baseline alcohol urge and mood was measured before an initial drink consumed (0.2 g/kg alcohol or lemonade). Four drinking ...
Maggs Jennifer L JL University of Arizona, Tucson, 85721-0078, United States. - - 2011
Given the dynamic fluctuating nature of alcohol use among emerging adults (Del Boca, Darkes, Greenbaum, & Goldman, 2004), patterns of alcohol use were modeled across 70 days in an intensive repeated-measures diary design. Two hundred first-year college students provided 10 weekly reports of their daily alcohol consumption via computer-assisted telephone ...
Connor Jennie L - - 2011
Background Previous research shows associations of geographical density of alcohol outlets with a range of alcohol-related harms. Socioeconomic conditions that are associated with both outlet density and alcohol-related outcomes may confound many studies. We examined the association of outlet density with both consumption and harm throughout New Zealand while controlling ...
Kuntsche Emmanuel - - 2010
Per definition, alcohol expectancies (after alcohol I expect X), and drinking motives (I drink to achieve X) are conceptually distinct constructs. Theorists have argued that motives mediate the association between expectancies and drinking outcomes. Yet, given the use of different instruments, do these constructs remain distinct when assessment items are ...
Coulson Carolyn E - - 2010
To describe the pattern of alcohol consumption and associated physical and lifestyle characteristics in a population-based sample of Australian men. A community-based age-stratified random sample of 1420 men (median age 56 years, range 20-93) participating in the Geelong Osteoporosis Study, an epidemiological study set in south-eastern Australia. Daily alcohol intake ...
Shaw Benjamin A BA State University of New York at Albany. - - 2011
To estimate patterns of long-term, within-person, changes in alcohol consumption among adults of different ages and assess key predictors of alcohol-use patterns over time. Data came from 3,617 adults, interviewed up to four times between 1986 and 2002. Multilevel multinomial logit models estimated the odds of abstinence and heavy drinking ...
Danielsson Anna-Karin - - 2010
This study aimed at identifying different alcohol drinking trajectories in early to late adolescence. We also examined whether certain factors predicted membership of a specific trajectory and to what extent trajectory membership was linked to later negative consequences. Data were drawn from a longitudinal cohort study starting with 1923 adolescents ...
Kawamoto Ryuichi - - 2010
Serum high molecular weight (HMW) adiponectin improves insulin sensitivity, and a decreased level of serum HMW adiponectin has been reported as a risk factor for the development of diabetes and coronary heart disease. This association may be further confounded by the alcohol drinking status, which is involved in the development ...
Gordon Ross R Institute for Social Marketing, Division of Marketing, University of Stirling, Stirlingshire, UK. - - 2010
To examine whether awareness of, and involvement with alcohol marketing at age 13 is predictive of initiation of drinking, frequency of drinking and units of alcohol consumed at age 15. A two-stage cohort study, involving a questionnaire survey, combining interview and self-completion, was administered in respondents' homes. Respondents were drawn ...
Holahan Charles J - - 2010
Growing epidemiological evidence indicates that moderate alcohol consumption is associated with reduced total mortality among middle-aged and older adults. However, the salutary effect of moderate drinking may be overestimated owing to confounding factors. Abstainers may include former problem drinkers with existing health problems and may be atypical compared to drinkers ...
Macneela Pádraig - - 2011
Binge drinking is a focus for concerns about young women's alcohol consumption at university. Twenty females, all regular binge drinkers, were interviewed individually and in focus groups to explore alcohol beliefs and exposure to harm. Four themes were identified in a thematic analysis. Alcohol use was associated with freedom but ...
Daeppen Jean-Bernard - - 2011
Brief motivational intervention (BMI) is one of the few effective strategies targeting alcohol consumption, but has not been tested in young men in the community. We evaluated the efficacy of BMI in reducing alcohol use and related problems among binge drinkers and in maintaining low-risk drinking among non-bingers. A random ...
Dale Caroline E - - 2010
OBJECTIVE: To estimate the cost of the extra time worked by Australian workers due to their co-workers' alcohol drinking. DESIGN, SETTING AND PARTICIPANTS: A secondary analysis of data obtained from 1677 Australian workers aged 18 years or older collected as part of a broader national study into the third-party harms ...
Correia Christopher J - - 2010
The aim of the current study was to initiate and describe the development of a Simulated Drinking Game Procedure (SDGP), a safe, efficient, and alcohol-free laboratory protocol for studying drinking game behavior. Fifty-two undergraduates completed the SDGP in a laboratory session, where participants played singles and/or doubles games of Beer ...
Ohtsu Tadahiro - - 2010
Over the past two decades, the liquor industry in Japan has strived to address alcohol-related problems through initiatives such as warnings in the various media. In this study, we conducted an Internet-based questionnaire survey to examine general consumer awareness of such warnings, and the media by which they are conveyed, ...
Aalto Mauri - - 2011
The performance of the Alcohol Use Disorders Identification Test (AUDIT) in screening for heavy drinking among the elderly has been unsatisfactory. The aim of the present study was to determine whether tailoring the cut point improves the performance of the AUDIT and its derivatives in this age group. From a ...
Caetano Raul R University of Texas School of Public Health, Dallas Regional Campus, 6011 Harry Hines Blvd., V8.112, Dallas, TX 75390-9128, USA. - - 2010
There have been limited trend studies examining variations on the patterns of alcohol consumption among Whites, Blacks, and Hispanics in the United States. The current paper reports national trends in drinking patterns, volume of drinking (number of drinks per month), binge drinking, and drinking to intoxication among Blacks, Whites, and ...
Denny Kevin - - 2010
Objectives A number of papers have investigated whether there is an association between handedness and alcohol consumption hypothesizing that alcoholism may be a consequence of atypical cerebral lateralization or a response to the stress involved in being a minority in a right-handed world. Research to date has mostly used small ...
Norström Thor - - 2010
Is alcohol related causally to violence, and if so, is the effect of drinking contingent on suppressed anger such that it is strongest among individuals who are highly inclined to withhold angry feelings? We addressed these questions by analysing panel data using a method that diminishes the effects of confounding ...
Adams Michael - - 2010
AIM: The study aimed to explore the place of taxation in preventing underage binge drinking in Germany. METHOD: We reviewed evidence on the role of excise taxes on alcohol in preventing alcohol problems and underage drinking. We analyzed historical German data on tax on alcoholic beverages and compared this with ...
Danielsson Anna-Karin - - 2010
This study aimed at identifying different alcohol drinking trajectories in early to late adolescence. We also examined whether certain factors predicted membership of a specific trajectory and to what extent trajectory membership was linked to later negative consequences. Data were drawn from a longitudinal cohort study starting with 1923 adolescents ...
Jones T A - - 2010
1. Forty-six flocks of commercially-reared Pekin ducks were studied to determine the effects of housing system and environment on the behaviour of farmed ducks and its correlation with physical condition. Houses differed predominantly in their ventilation, drinking, feeding and brooding systems, and were indicative of systems currently in use in ...
Lambert Nathaniel M - - 2010
Four methodologically diverse studies (N = 1,758) show that prayer frequency and alcohol consumption are negatively related. In Study 1 (n = 824), we used a cross-sectional design and found that higher prayer frequency was related to lower alcohol consumption and problematic drinking behavior. Study 2 (n = 702) used ...
Beck Kenneth H KH Department of Public and Community Health, University of Maryland School of Public Health, College Park, Maryland 20740, - - 2010
Alcohol-impaired driving is a major public health problem. National studies indicate that about 25% of college students have driven while intoxicated in the past month and an even greater percentage drive after drinking any alcohol and/or ride with an intoxicated driver. The purpose of this investigation was to examine the ...
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