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Results 301 - 350 of 975
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La Rocca Gaspare - - 2011
MicroRNA145 (miR145), a tumor suppressor miR, has been reported to inhibit growth of human cancer cells, to induce differentiation and to cause apoptosis, all conditions that result in growth arrest. In order to clarify the functional effects of miR145, we have investigated its expression in diverse conditions and different cell ...
Serman L - - 2011
Due to it ability to invade deep into endometrium, as well as into other tissues at ectopic sites (testis, kidney capsule), throphoblast plays an important role in shaping the future placenta. To accomplish this task, it is necessary for throphoblast cells to differentiate into highly invasive throphoblast giant cells (TGC). ...
Zhang Hongbo - - 2011
Cell differentiation increases UDP-glucuronosyltransferase (UGT) gene expression in Caco-2 cells. Glucuronidation of 13 UGT substrates, 1-naphthol, diclofenac, epitestosterone, estradiol, ethinylestradiol, indomethacin, oxazepam, R- and S-propranolol, propofol, testosterone, trifluoperazine, and zidovudine, were studied to derive a broad view on the effect of cell differentiation on the glucuronidation activities of different human ...
Ock Jiyeon - - 2011
2'-Benzoyloxycinnamaldehyde (BCA), one of the derivatives of 2'-hydroxycinnamaldehyde (HCA) isolated from the bark of Cinnamomum cassia, induces apoptosis in human cancer cells. We found that BCA induces stronger antiproliferative effects in K-ras-transformed cells (RK3E-ras) than in isogenic non-transformed cells (RK3E). Treatment of RK3E-ras with BCA resulted in increased ROS generation ...
Gao Xiaobo X Department of Medicine and Physiology and Cellular Biophysics, College of Physicians and Surgeons of Columbia University, New York, NY 10032, - - 2010
Acid-base transport in the renal collecting tubule is mediated by two canonical cell types: the β-intercalated cell secretes HCO(3) by an apical Cl:HCO(3) named pendrin and a basolateral vacuolar (V)-ATPase. Acid secretion is mediated by the α-intercalated cell, which has an apical V-ATPase and a basolateral Cl:HCO(3) exchanger (kAE1). We ...
Zheng Dan - - 2011
LNX protein is the first described PDZ domain-containing member of the RING finger-type E3 ubiquitin ligase family. Studies have approved that LNX could participate in signal transduction, such as Notch pathway, and play an important role in tumorigenesis. In this study, we found that down-regulation of LNX resulted in G0/G1 ...
Yu Weishi - - 2011
Cell growth and proliferation are tightly controlled via the regulation of the p53-MDM2 feedback loop in response to various cellular stresses. In this study, we identified a nucleolar protein called PAK1IP1 as another regulator of this loop. PAK1IP1 was induced when cells were treated with chemicals that disturb ribosome biogenesis. ...
Guo Qijie - - 2010
Earth abundant copper-zinc-tin-chalcogenide (CZTSSe) is an important class of material for the development of low cost and sustainable thin film solar cells. The fabrication of CZTSSe solar cells by selenization of CZTS nanocrystals is presented. By tuning the composition of the CZTS nanocrystals and developing a robust film coating method, ...
Wang Xuening X Department of Pathology and Laboratory Medicine, New Jersey Medical School, University of Medicine and Dentistry New Jersey, Newark, - - 2010
Acute myelogenous leukemia (AML) is a disease characterized by dysregulated cell proliferation associated with impaired cell differentiation, and current treatment regimens rarely save the patient. Thus, new mechanism-based approaches are needed to improve prognosis of this disease. We have investigated in preclinical studies the potential anti-leukemia use of the plant-derived ...
Jun Do Youn - - 2010
The effect of mollugin, isolated from the roots of Rubia cordifolia L., on cell viability, apoptosis and adipogenesis in 3T3-L1 preadipocytes was investigated. The inhibitory effect of mollugin (40-60 µm) on cell viability was more significant in differentiated adipocytes than in 3T3-L1 preadipocytes. In 3T3-L1 cells, the cytotoxicity of mollugin was ...
Pramanik Sudipta - - 2011
The effects of entrapment on nucleic acid content and microbial diversity of mixed cultures in biological municipal wastewater treatment were investigated. Deoxyribonucleic acid content increased 1.6-5.5 times more in alginate entrapped cells than in free and polyvinyl alcohol (PVA) entrapped cells. PVA entrapment resulted in 1.1- to 5.9-fold more increases ...
Lee Yong Joo - - 2011
In Saccharomyces cerevisiae, the accepted theory is that due to TCA cycle dysfunction, the Δcit1 mutant lacking the mitochondrial enzyme citrate synthase (Cit1) cannot grow on acetate, regardless of the presence of the peroxisomal isoenzyme (Cit2). In this study, we re-evaluated the roles of Cit1 and Cit2 in acetate utilization ...
Thomadaki Hellinida - - 2011
We synthesized, characterized and studied the anticancer properties of a new water-soluble peroxo niobium complex (K(3)[Nb(Asc)(O(2))(3)]·4H(2)O (Asc = ascorbate anion C(6)H(6)O(6)(2-))), as well as that of ascorbic acid, in human leukemic cells. The complex was synthesized and characterized by elemental, IR, Raman, thermogravimetric analysis, detailed NMR and mass spectra analysis. ...
de Mesquita Mariana Laundry - - 2011
In the search for new anti-cancer compounds, Brazilian Cerrado plant species have been investigated. The hexane root bark extract of Kielmeyera coriacea lead to a mixture of δ-tocotrienol (1) and its dimer (2). The structures of both compounds 1 and 2 were established based on detailed 1D and 2D NMR ...
Tadanaga Kiyoharu - - 2010
An alkaline-type direct ethanol fuel cell (DEFC) using a natural clay electrolyte with non-platinum catalysts is proposed. So-called hydrotalcite clay, Mg–Al layered double hydroxide intercalated with CO₃²⁻, is shown to be a hydroxide ion conductor. An alkaline-type DEFC using this natural clay as the electrolyte and aqueous solution of ethanol ...
Shan Guo-Bin - - 2010
Er(3+),Yb(3+) co-doped LaF₃-TiO₂ nanocomposites (UC-TiO₂) are inserted as a middle layer in a novel tri-layer photoanode design (see Figure) of a dye-sensitized solar cell (DSSC). The Er(3+),Yb(3+) co-doped LaF₃ part of the nanocomposite helps capture near-infrared (NIR) light by converting it into visible light absorbable by the dye hence opening ...
Zhao Guangjin - - 2010
A power conversion efficiency of 6.48% was achieved for polymer solar cells based on poly(3-hexylthiophene) (P3HT) as donor and indene-C₆₀ bisadduct (ICBA) as acceptor with an open-circuit voltage of 0.84 V, a short-circuit current of 10.61 mA/cm², and a fill factor of 72.7% under irradiation at AM1.5G, 100 mW/cm² at ...
Jang Jum Suk - - 2010
Mesoporous tungsten carbides displayed an excellent solar conversion efficiency (7.01%) as a counter electrode for dye sensitized solar cells under 100 mW cm(-2), AM 1.5G illumination, which corresponded to ca. 85% of the efficiency of the conventional platinum electrode.
Liu Jia - - 2010
Hairy and enhancer of split 1 (Hes1) and Hes5 are target genes for the mammalian Notch pathway, which are highly expressed in epithelia in the process of embryogenesis or in neural stem cells, inhibit cell differentiation via the Notch-Hes-Hash signaling, and promote the survival of stem cells. Either Hes1 or ...
Kronenberg Nils M - - 2010
Identically configured bulk heterojunction organic solar cells based on merocyanine dye donor and fullerene acceptor compounds (see figure) are manufactured either from solution or by vacuum deposition, to enable a direct comparison. Whereas the former approach is more suitable for screening purposes, the latter approach affords higher short-circuit current density ...
Farmer Charles M - - 2010
OBJECTIVES: Prior research has estimated that crash risk is 4 times higher when talking on a cell phone versus not talking. The objectives of this study were to estimate the extent to which drivers talk on cell phones while driving and to compute the implied annual number of crashes that ...
Martino H F - - 2010
The aim of this study was to determine if bone marrow mononuclear cell (BMMC) transplantation is safe for moderate to severe idiopathic dilated cardiomyopathy (IDC). Clinical trials have shown that this procedure is safe and effective for ischemic patients, but little information is available regarding non-ischemic patients. Twenty-four patients with ...
Mumin Abdul M - - 2011
In this paper, foam-structured fluorescent mesoporous silica nanoparticles (FMSNs) are produced in a sol-gel method with the introduction of a phosphonate functional group. It is found that the phosphonate functionalized FMSNs with the foam structure minimizes the aggregation of FMSNs in solution. The average particle size of the FMSNs without ...
Koyama Koichiro - - 2010
Two novel indole alkaloids, alsmaphorazines A and B, were isolated from the leaves of Alstonia pneumatophora (Apocynaceae), and their structures were determined on the basis of the 2D NMR and MS spectral analysis. These alkaloids possessed a new skeleton consisting of an 1,2-oxazinane and an isoxazolidine chromophore. The absolute configuration ...
Brett Daniel J L - - 2010
Fuel cell performance is determined by the complex interplay of mass transport, energy transfer and electrochemical processes. The convolution of these processes leads to spatial heterogeneity in the way that fuel cells perform, particularly due to reactant consumption, water management and the design of fluid-flow plates. It is therefore unlikely ...
Ibanez Marta - - 2010
The presence of ganglia associated with the laryngeal nerves is well documented. In man, these ganglia have been less well studied than in other species and, in particular, the cell types within these ganglia are less well characterized. Using a panel of antibodies to a variety of markers found in ...
Yamada Yusuke - - 2010
Hydrogen peroxide was electrochemically produced by reducing oxygen in an aqueous solution with [Co(TCPP)] as a catalyst and photovoltaic solar cell operating at 0.5 V. Hydrogen peroxide thus produced is utilized as a fuel for a one-compartment fuel cell with Ag-Pb alloy nanoparticles as the cathode.
Fakhrullin Rawil F - - 2010
A new class of colloid structures, celloidosomes, has been developed which represent hollow microcapsules whose membranes consist of a single monolayer of living cells. Two routes for producing these structures were designed based on templating of: (i) air bubbles and (ii) anisotropic microcrystals of calcium carbonate with living cells, which ...
Osman M H - - 2010
Recent key developments in microbial fuel cell technology are reviewed. Fuel sources, electron transfer mechanisms, anode materials and enhanced O(2) reduction are discussed in detail. A summary of recently developed microbial fuel cell systems, including performance measurements, is conveniently provided in tabular form. The current challenges involved in developing practical ...
Fan Sheng-Qiang - - 2010
Ordered multimodal porous carbon (OMPC) was explored as a counter electrode in ruthenium complex dye-sensitized solar cells (DSSCs) and CdSe quantum-dot solar cells (QDSCs). The unique structural characteristics such as large surface area and well-developed three-dimensional (3-D) interconnected ordered macropore framework with open mesopores embedded in the macropore walls make ...
Huang Shuqing - - 2010
A new kind of fibrous quantum dot sensitized solar cell has been designed and fabricated by using CdS and CdSe co-sensitized TiO(2) nanotubes on Ti wire as the photoanode and highly active Cu(2)S as the counter electrode. By optimizing the CdSe deposition time and the length of the nanotube, a ...
Honda Satoshi - - 2010
Multi-colored dye-sensitized polymer/fullerene solar cells with two different near-IR dyes, silicon phthalocyanine bis(trihexylsilyl oxide) (SiPc) and silicon naphthalocyanine bis(trihexylsilyl oxide) (SiNc), enhanced power conversion efficiency up to 4.3%, compared to that of the individual ternary blend solar cells with a single dye under AM1.5G illumination.
Olins Ada L AL Department of Biology, Bowdoin College, Brunswick, ME, - - 2010
The principal human blood granulocyte (neutrophil) possesses a lobulated and deformable nucleus, important to facilitate rapid egress from blood vessels as these cells migrate to sites of bacterial or fungal infection. This unusual nuclear shape is a product of elevated levels of an integral membrane protein of the nuclear envelope ...
Shobayashi Yasuhiro - - 2010
Endovascular treatment of cerebral aneurysms using stents has advanced markedly in recent years. Mechanically, a cerebrovascular stent must be very flexible longitudinally and have low radial stiffness. However, no study has examined the stress distribution and deformation of cerebrovascular stents using the finite element method (FEM) and experiments. Stents can ...
Lee Chang Yeon - - 2010
A pi-extended porphyrin possessing two anchoring groups has been synthesized and successfully applied to dye-sensitized solar cells with a power conversion efficiency of 5.5%, rendering it comparable to the performance of N719-sensitized solar cells under the conditions employed here.
Lin Li-Yen - - 2010
Two new organic dyes adopting coplanar diphenyl-substituted dithienosilole as the central linkage have been synthesized, characterized, and used as the sensitizers for dye-sensitized solar cells (DSSCs). The best DSSC exhibited a high power conversion efficiency up to 7.6% (TP6CADTS) under AM 1.5G irradiation, reaching approximately 96% of the ruthenium dye ...
Preat Julien - - 2010
This work reports a theoretical study of the photovoltaic properties of a series of original conjugated metal-free organic dyes containing the triphenylamine (TPA) moiety. These compounds have recently been develop for dye sensitized solar cells (DSSCs). Our (TD)DFT-based procedure made it possible to get insights into the geometrical and electronic ...
Gabriel Margaret A - - 2010
Nano-structured electrode degradation in state-of-the-art polymer electrolyte membrane fuel cells (PEMFCs) is one of the main shortcomings that limit the large-scale development and commercialization of this technology. During normal operating conditions of the fuel cell, the PEMFC lifetime tends to be limited by coarsening of the cathode's Pt-based catalyst and ...
Giliano N Y - - 2010
The dynamics of intracellular levels of superoxide and NO after cell treatment with NO synthase inhibitors were studied in human cells expressing various NOS isoforms: endotheliocytes and ECV-304 (eNOS) and carcinoma cells and HeLa-G63 (iNOS). Cytometric analysis of changes in the cell fluorescence intensity was carried out using superoxide and ...
Seol Minsu - - 2010
In this communication, a novel CdSe/CdS/ZnO nanowire array fabricated by a 3-step solution-based method was used as a photoanode of a quantum dot sensitized solar cell, which generated a maximum power conversion efficiency of 4.15%.
Pringle Jennifer M - - 2010
Electrodeposition of poly(3,4-ethylenedioxythiophene) onto conducting plastic allows the cheap and facile synthesis of plastic cathodes for dye-sensitised solar cells, having excellent solar cell efficiency (8%), at a fraction of the cost of platinised plastic.
Rousseau Theodulf - - 2010
Fixation of a 5-hexyl-2,2'-bithienyl unit on a conjugated BODIPY donor increases the conversion efficiency of the resulting molecular bulk heterojunction solar cells from 1.30 to 2.20%.
Wei Yaguang - - 2010
We present a new approach to fabricate three-dimensional (3D) dye-sensitized solar cells (DSSCs) by integrating planar optical waveguide and nanowires (NWs). The ZnO NWs are grown normally to the quartz slide. The 3D cell is constructed by alternatively stacking a slide and a planar electrode. The slide serves as a ...
Maltais Simon - - 2010
Cardiac cell therapy has emerged as a controversial yet promising therapeutic strategy. Both experimental data and clinical applications in this field have shown modest but tangible benefits on cardiac structure and function and underscore that transplanted stem-progenitor cells can attenuate the postinfarct microenvironment. The paracrine factors secreted by these cells ...
Rustomji Cyrus S - - 2010
We have designed and constructed dye sensitized solar cells based on new, 3-D configurations of TiO(2) nanotubes. The overall efficiency of our best cells is 5.0% under standard air mass 1.5 global (AM 1.5 G) solar conditions, and the incident photon-to-current efficiency exceeds 60% over a broad part of the ...
Zhang Guobing - - 2010
New donor/acceptor polymers PBDTDPT1 and PBDTDPT2 with alternating benzodithiophene and N-alkylated dioxopyrrolo-thiophene were synthesized. The new polymers had deep HOMO levels of -5.42 and -5.44 eV for PBDTDPT1 and PBDTDPT2, respectively. A PBDTDPT2 based BHJ solar cell device achieved a PCE of 4.79% and V(oc) of 0.91 V.
Kalita Golap - - 2010
Here, we report incorporation of multiwalled carbon nanotubes (MWNTs) in Poly(3-octylthiophene)/fullerene heterojunction solar cells. Multi-walled carbon nanotubes (MWNTs) were functionalized by oxygen plasma treatment. Photoelectron spectroscopy study of oxygen plasma treated MWNTs shows surface modification with hydroxyl and carboxyl groups. Plasma treated MWNTs were combined with Poly(3-octylthiophene) and solar cell ...
Peng Kui-Qing - - 2010
We demonstrate Si nanohole arrays as a superior sunlight-absorbing nanostructure for photovoltaic solar cell applications. Under 1 sun AM1.5G illumination, a Si nanohole solar cell with p-n junctions via P diffusion exhibited a open-circuit voltage of 566.6 mV, a short-circuit current density of 32.2 mA/cm(2), and a remarkable power conversion ...
Creydt Virginia Pistone - - 2010
Stromal tissue regulates the development and differentiation of breast epithelial cells, with adipocytes being the main stromal cell type. The aim of the present study was to evaluate the effect of adipocyte differentiation on proliferation and migration, as well as to assess the activity of heparanase and metalloproteinase-9 (MMP-9), in ...
Hwang Jae-Yeol - - 2010
Nanocrystalline CdS-sensitized solar cells (CdS-SSCs) based on mesoporous TiO(2) were fabricated by the spray pyrolysis deposition method. The energy conversion efficiency of these cells was drastically increased (156%) by modifying the junction structure through post-treatment that included soaking in a dilute TiCl(4) aqueous solution and subsequent thermal annealing. We propose ...
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