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Cui Xue-Ping XP Key Laboratory of Green Printing, Institute of Chemistry, Chinese Academy of Sciences, Beijing, 100190, China. kjjiang@iccas.ac.cn - - 2014
The perovskite CH3NH3PbI3 was prepared on a mesoscopic TiO2 film, starting from electrodepositing PbO, to iodination to PbI2, and then interdiffusion reaction with CH3NH3I. The as-prepared film was used as a light absorber for the perovskite solar cells, exhibiting a high PCE of 12.5% under standard AM 1.5 conditions.
Skotis G D GD School of Engineering, University of Glasgow, Glasgow, G12 8LT, UK. - - 2014
Advances in diagnostics, cell and stem cell technologies drive the development of application-specific tools for cell and particle separation. Acoustic micro-particle separation offers a promising avenue for high-throughput, label-free, high recovery, cell and particle separation and isolation in regenerative medicine. Here, we demonstrate a novel approach utilizing a dynamic acoustic ...
Li Sixing S Department of Engineering Science and Mechanics, The Pennsylvania State University, University Park, PA 16802, USA. - - 2014
Cell/bead washing is an indispensable sample preparation procedure used in various cell studies and analytical processes. In this article, we report a standing surface acoustic wave (SSAW)-based microfluidic device for cell and bead washing in a continuous flow. In our approach, the acoustic radiation force generated in a SSAW field ...
Kierans Andrea S AS 1 Department of Radiology, New York University Langone Medical Center, New York, - - 2014
OBJECTIVE. The purpose of this article is to evaluate differences in texture measures on apparent diffusion coefficient (ADC) maps between low- and high-stage clear cell renal cell carcinomas (RCCs). MATERIALS AND METHODS. In this retrospective study, 61 patients with clear cell RCC at pathologic examination and who underwent preoperative MRI ...
Boghaert Eline E Department of Chemical and Biological Engineering, Princeton University, Princeton, New Jersey, United States of - - 2014
Ductal carcinoma in situ (DCIS) is a heterogeneous group of non-invasive lesions of the breast that result from abnormal proliferation of mammary epithelial cells. Pathologists characterize DCIS by four tissue morphologies (micropapillary, cribriform, solid, and comedo), but the underlying mechanisms that distinguish the development and progression of these morphologies are ...
Kim Jong H JH Department of Materials Science and Engineering, University of Washington, Seattle, Washington, 98195-2120, - - 2014
An effective approach to significantly increase the electrical conductivity of a NiOx hole-transporting layer (HTL) to achieve high-efficiency planar heterojunction perovskite solar cells is demonstrated. Perovskite solar cells based on using Cu-doped NiOx HTL show a remarkably improved power conversion efficiency up to 15.40% due to the improved electrical conductivity ...
Qiu Qianqian Q Center of Drug Discovery, State Key Laboratory of Natural Medicines, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing, 210009, PR - - 2014
A novel coumarin-based fluorescence probe has been constructed for the selective and sensitive detection of hydrogen sulfide (H2 S). This probe displays high sensitivity and linearity to H2 S in degassed PBS buffers and fetal bovine serum. It reacts with H2 S with high selectivity over Cys, GSH and other ...
Zhang Huiyuan H Labratory of Medical Genetics, Harbin Medical University, 157 Baojian Rd, Nangang Dist, Harbin, 150081, Heilongjiang, - - 2014
High-risk neuroblastoma often develops resistance to high-dose chemotherapy. The mTOR signaling cascade is frequently deregulated in human cancers and targeting mTOR signaling sensitizes many cancer types to chemotherapy. Here, using a panel of neuroblastoma cell lines, we found that the mTOR inhibitor INK128 showed inhibitory effects on both anchorage-dependent and ...
Cui Jin - - 2014
Herein we report on an investigation of CH3NH3PbI3 planar solar cell, showing that significant power conversion efficiency (PCE) improvement from 4.88% to 6.13% by introducing a homogeneous and uniform NiO blocking interlayer fabricated with reactive magnetron sputtering method. The sputtered NiO layer exhibits enhanced crystallization, high transmittance and uniform surface ...
Guckenberger David J DJ Department of Biomedical Engineering, Wisconsin Institutes for Medical Research, University of Wisconsin-Madison, Madison, WI, - - 2014
Cell-based assays are essential tools used by research labs in a wide range of fields, including cell biology, toxicology, and natural product discovery labs. However, in some situations, the need for cell-based assays does not justify the costs of maintaining cell culture facilities and retaining skilled staff. The kit-on-a-lid assay ...
Zhou Shao-Lai SL Liver Surgery Department, Liver Cancer Institute, Zhongshan Hospital, Fudan University; Key Laboratory of Carcinogenesis and Cancer Invasion (Fudan University), Ministry of Education, Shanghai 200032, China; Institute of Biomedical Sciences, Fudan University, Shanghai, - - 2014
Upregulation of CXCR2 in tumor cells has been documented in several types of cancer. As one of its ligands, CXCL5 is associated with neutrophil infiltration and poor prognosis in hepatocellular carcinoma (HCC). However, little is known about the role of CXCR2/CXCL5 axis in the invasion and metastasis of HCC cells. ...
Olsen T R TR Department of Bioengineering, Clemson University, 301 Rhodes Research Center, Clemson, SC 29634 - - 2014
Cellular spheroids have been investigated as tissue engineered building blocks that can be fused to form functional tissue constructs. While spheroids can be assembled using passive contacts for the fusion of complex tissues, physical forces can be used to promote active contacts to improve tissue homogeneity and accelerate tissue fusion. ...
Najafi Rezvan R Razi Drug Research Center, Iran University of Medical Sciences, Tehran, 1449614535, - - 2014
Hyperglycemia plays an important role in the development of diabetic neuropathy. In this study, we investigated the protective effects of alpha lipoic acid (ALA) against high glucose-induced neurotoxicity in PC12 cells as a suitable in vitro model for studying neuronal functions. PC12 cells were treated with high glucose (25 mg/ml for ...
Endo Aya A Human Health Science, Kyoto University, Sakyo-ku Shogoin Kawahara-cyo 53, Kyoto, 606-8507, - - 2014
We aimed to observe morphological changes in the spleen from the emergence of the primordium to the end of the embryonic period by using histological serial sections of 228 samples. Between Carnegie stages (CSs) 14 and 17, the spleen was usually recognized as a bulge in the dorsal mesogastrium (DM), ...
Guo Fei - - 2014
The tandem architecture is the most relevant concept to overcome the efficiency limit of single-junction photovoltaic solar cells. Series-connected tandem polymer solar cells (PSCs) have advanced rapidly during the past decade. In contrast, the development of parallel-connected tandem cells is lagging far behind due to the big challenge in establishing ...
Liang Lusheng - - 2014
Suitable electrode interfacial layers are essential to the high performance of perovskite planar heterojunction solar cells. In this letter we report magnetron sputtered zinc oxide (ZnO) film as the cathode interlayer for methyl ammonium lead iodide (CH3NH3PbI3) perovskite solar cell. Scanning electron microscopy and X-ray diffraction analysis demonstrate that the ...
Yap Benjamin H J BH Algal Processing Group, Department of Chemical and Biomolecular Engineering, The University of Melbourne, Parkville, Victoria 3010, - - 2014
The energy consumption of high pressure homogenisation (HPH) was analysed to determine the feasibility of rupturing algal cells for biodiesel production. Experimentally, the processing capacity (i.e. flow rate), power draw and cell disruption efficiency of HPH were independent of feed concentration (for Nannochloropsis sp. up to 25%w/w solids). Depending on ...
Repetto Guillermo G Departamento de Biología Molecular e Ingeniería Bioquímica, Área de Toxicología, Universidad Pablo de Olavide, Carretera de Utrera km. 1, 41013 Seville, Spain. Electronic address: - - 2014
Thermoluminescence is a simple technique very useful for studying electron transfer reactions on photosystem II (standard thermoluminescence) or the level of lipid peroxidation in membranes (high temperature thermoluminescence) in photosynthetic organisms. Both techniques were used to investigate the effects produced on Chlorella vulgaris cells by six compounds: the chemical intermediates ...
Massaguer Anna A Departament de Biologia, Universitat de Girona, Campus Montilivi, E-17071 Girona, Spain. - - 2014
Conjugates of a Pt(iv) derivative of picoplatin with monomeric (Pt-c(RGDfK), ) and tetrameric (Pt-RAFT-{c(RGDfK)}4, ) RGD-containing peptides were synthesized with the aim of exploiting their selectivity and high affinity for αVβ3 and αVβ5 integrins for targeted delivery of this anticancer metallodrug to tumor cells overexpressing these receptors. Solid- and solution-phase ...
Hua Nengbin N Department of Materials Science and Engineering, Fujian University of Technology, 350118 Fuzhou, China; Department of Materials Science and Engineering, Fuzhou University, 350116 Fuzhou, China. Electronic address: - - 2014
The present study designs and prepares Ni-free Zr60+xTi2.5Al10Fe12.5-xCu10Ag5 (at.%, x=0, 2.5, 5) bulk metallic glasses (BMGs) by copper mold casting for potential biomedical application. The effects of Zr content on the in vitro biocompatibility of the Zr-based BMGs are evaluated by investigating mechanical properties, bio-corrosion behavior, and cellular responses. It ...
Kuroda N N Naoto Kuroda, MD, Department of Diagnostic Pathology, Kochi Red Cross Hospital, Shin-honmachi 2-13-51, Kochi City, Kochi 780-8562, Japan, tel. +81-88-822-1201 ext. 1610, fax +81-88-822-1056, e-mail: - - 2014
In this article, we present a rare case of renal pelvic carcinoma. The imaging examination of a 75-year-old Japanese man disclosed the left renal pelvic tumor. The histological examination showed the finding of predominant undifferentiated discohesive mononuclear cells with abundant osteoclast-like giant cells and a minor component of papillary urothelial ...
Ran Niva A NA Center for Polymers and Organic Solids, Department of Chemistry and Biochemistry, University of California, Santa Barbara, Santa Barbara, CA, 93106, - - 2014
World-record-performing bulk-heterojunction (BHJ) small molecule solar cells are realized by careful optimization of their solid-state morphology. These BHJ films are transformed from an intimate mixture of the donor and acceptor phases to films with well-defined donor crystallites. In addition to correlating with a high photovoltaic response, the donor crystallites also ...
Kim Jeehwan J IBM T. J. Watson Research Center, Yorktown Heights, NY, 10598, - - 2014
On page 7427, J. Kim, H. Hiroi, T. K. Todorov, D. B. Mitzi, and co-workers report high-efficiency Cu2 ZnSn(S,Se)4 solar cells by applying In2 S3 /CdS double emitters. This new structure offers a high doping concentration within the Cu2 ZnSn(S,Se)4 solar cells, resulting in substantial enhancement in the open-circuit voltage. ...
Jung Hyun Suk HS School of Advanced Materials Science and Engineering, Sungkyunkwan University (SKKU), Suwon, 440-746, - - 2014
Perovskite solar cells based on organometal halide light absorbers have been considered a promising photovoltaic technology due to their superb power conversion efficiency (PCE) along with very low material costs. Since the first report on a long-term durable solid-state perovskite solar cell with a PCE of 9.7% in 2012, a ...
Meidanchi Alireza A Department of Physics, Payame Noor University (PNU), P.O. Box 19395-3697, Tehran, Iran; Department of Physics, Sharif University of Technology, P.O. Box 11155-9161, Tehran, - - 2015
Nanoparticles of high-Z elements exhibit stronger photoelectric effects than soft tissues under gamma irradiation. Hence, they can be used as effective radiosensitizers for increasing the efficiency of current radiotherapy. In this work, superparamagnetic zinc ferrite spinel (ZnFe2O4) nanoparticles were synthesized by a hydrothermal reaction method and used as radiosensitizers in ...
Sui Binglin B Department of Chemistry and ‡CREOL, The College of Optics and Photonics, University of Central Florida , Orlando, Florida 32816, United - - 2014
A novel boron-dipyrromethene (BODIPY) based fluorescence turn-on sensor for detecting Fe(3+) in aqueous media is reported with 23-fold fluorescence enhancement. The sensor is comprised of a combination of BODIPY fluorophore and a new Fe(3+)-recognizing cryptand that exhibits high selectivity, sensitivity, and reversibility toward Fe(3+) detection. Cell imaging studies demonstrate that ...
Davis Reeta R School of Biomolecular and Biomedical Science, University College Dublin, Belfield, Dublin 4, Ireland; Technology Centre for Biorefining and Bioenergy, Orbsen Building, National University of Ireland, Galway, - - 2014
High Cell Density (HCD) cultivation of bacteria is essential for the majority of industrial processes to achieve high volumetric productivity (g L(-1) h(-1) ) of a bioproduct of interest. This study developed a fed batch bioprocess using glucose as sole carbon and energy source for the HCD of the well ...
Ríos M M Departamento de Fisioloxía, CIMUS, IDIS, Facultade de Medicina, Universidade de Santiago de Compostela, Santiago de Compostela, - - 2014
Metabolic adaptations are essential during tumour growth to maintain the high proliferation levels exhibited by cancer cells. In this study, we examined the transformations that occurred in the lipid metabolism in astrocytic tumours, and the possible role of the fuel-sensing enzyme AMPK. Metabolic targets might help design new and effective ...
Sušec Maja M Centre of Excellence PoliMaT, Tehnološki park 24, Ljubljana, Slovenia; Polymer Technology College, Ozare 19, Slovenj Gradec, - - 2014
Open porous microcellular polymers with high degrees of porosity are prepared from divinyl adipate and pentaerythritol tetrakis(3-mercaptopropionate) by thiol-ene polymerization within high internal phase emulsions. The influence of monomer ratio, droplet phase volume, and emulsion stirring rate on the morphology and mechanical properties of the products is studied. The newly ...
Ameen Sadia - - 2014
The high performance perovskite solar cell was fabricated using distinguished morphology of polyaniline nanoparticles (PANI-NPs) as efficient hole transporting layer (HTL) with methyl ammonium lead iodide perovskite (CH3NH3PbI3) as sensitizer. PANI NPs were simply synthesized by the oxidative chemical polymerization of aniline monomer at 0-5 oC. The reasonable solar-to-electricity conversion ...
Lee Hyo Won - - 2014
We reported a ratiometric two-photon fluorescent probe (SG1) for β-galactosidase (β-gal) and its application to quantitative detection of β-gal activity during cellular senescence in live cells and in aged tissues. This probe is characterized by a significant two-photon excited fluorescence, a marked blue-to-yellow emission color change in response to β-gal, ...
Wang Zhong Z Department of Cardiothoracic Surgery, The Affiliated Jiangyin Hospital of Southeast University, Jiangyin 214400, - - 2014
Aim:To investigate the effects of pyrroloquinoline quinone (PQQ), an oxidoreductase cofactor, on high glucose-induced mouse endothelial cell damage in vitro.Methods:Mouse brain microvascular endothelial bEND.3 cells were exposed to different glucose concentrations (5.56, 25 and 40 mmol/L) for 24 or 48 h. The cell viability was examined using MTT assay. Flow ...
Liu Wei W School of Chemical & Biomolecular Engineering and RBI at Georgia Tech, Georgia Institute of Technology, 500 10th Street N.W., Atlanta, GA 30332-0620 (USA); College of Chemistry and Chemical Engineering, Hunan University - - 2014
Herein, we report high-performance fuel cells that are catalyzed solely by polyoxometalate (POM) solution without any solid metal or metal oxide. The novel design of the liquid-catalyst fuel cells (LCFC) changes the traditional gas-solid-surface heterogeneous reactions to liquid-catalysis reactions. With this design, raw biomasses, such as cellulose, starch, and even ...
Terashima Mia M Carnegie Institution for Science, Department of Plant Biology, 260 Panama Street, Stanford, California, 94305, - - 2014
There is significant interest in farming algae for the direct production of biofuels and valuable lipids. Chlamydomonas reinhardtii is the leading model system for studying lipid metabolism in green algae, but current methods for isolating mutants with perturbed lipid content in this organism are slow and tedious. Here, we present ...
Zavec Apolonija Bedina AB National Institute of Chemistry, Hajdrihova 19, Ljubljana, Slovenia Medical Center for Molecular Biology, Faculty of Medicine, University of Ljubljana, - - 2014
Archaeosomes are a type of liposomes prepared from the polar lipids of various Archaeobacteria. These have unique structural features that increase the lipid bilayer's stability even under high temperatures, low or high pH, presence of phospholipases and bile salts. This makes them ideal as basis for the development of new ...
Bergner Benjamin J - - 2014
Non-aqueous Li-O2 batteries are an intensively studied future energy storage technology due to their high theoretical energy density. However, a number of barriers prevent a practical application, and one of the major challenges is the reduction of the high charge overpotential: Whereas lithium peroxide (Li2O2) is formed during discharge at ...
Misra Chitra Seetharam CS Molecular Biology Division, Bhabha Atomic Research Centre, Trombay, Mumbai-400085, - - 2014
Bioremediation is an attractive option for the treatment of radioactive waste. We provide a proof of principle for augmentation of uranium bioprecipitation using the radiation inducible promoter, Pssb from Deinococcus radiodurans. Recombinant cells of D. radiodurans carrying acid phosphatase gene, phoN under the regulation of Pssb when exposed to 7 ...
De Mello Walmor C WC School of Medicine, Medical Sciences Campus, UPR, San Juan, PR 00936, USA. Electronic address: - - 2014
The influence of high glucose solution on the chemical communication between cardiac cells was investigated in cell pairs isolated from the left ventricle of adult Wistar Kyoto rats. For this, Lucifer Yellow CH was dialyzed into one cell of the pair using the whole cell clamp technique, and the diffusion ...
Wieneke Ralph - - 2014
The selective and fast labeling of proteins in living cells is a major challenge. Live-cell labeling techniques require a high specificity, high labeling density, and cell permeability of the tagging molecule to target the protein of interest. Here, we report on the site-specific, rapid and efficient labeling of endogenous and ...
Ocakoglu Kasim K Advanced Technology Research & Application Center, Mersin University, Ciftlikkoy Campus , Mersin , Turkey - - 2014
Abstract The biological potential of a synthetic copper chlorophyll derivative was investigated via in vivo and in vitro experiments. The Cu-chlorophyll derivative photosensitizer (Cu-PH-A) was labeled with (131)I with high efficiency (92.9 ± 4.2%) using the iodogen method. Cell culture studies were performed with the MCF-7 and MDAH-2774 cell lines after radiolabeling. ...
Frescatada-Rosa Márcia M Department of Plant Physiology, Umeå Plant Science Centre (UPSC), Umeå University, SE-90187, Umeå, - - 2014
Membranes of eukaryotic cells contain high-lipid-order, sterol-rich domains thought to mediate temporal and spatial organization of cellular processes. Sterols are crucial for execution of cytokinesis, the last stage of cell division, in diverse eukaryotes. The cell plate of higher plant cells is the membrane structure that separates daughter cells during ...
Yu Bo B Larix Bioscience, LLC, 1230 Bordeaux Drive, Sunnyvale, CA 94089, USA Panorama Research, Inc., Sunnyvale, CA 94089, USA - - 2014
Generation of high-productivity cell lines remains a major bottleneck in therapeutic antibody development. Conventional cell line development often depends on gene amplification methodologies using dihydrofolate reductase or glutamine synthetase. Higher productivity is associated with an increased gene copy number. However, lack of selection pressure under the conditions of large-scale manufacturing ...
Kumar Mulmudi Hemant MH Energy Research Institute @NTU (ERI@N), Research Techno Plaza, X-Frontier Block, Level 5, 50 Nanyang Drive, Singapore, 637553, Singapore; School of Materials Science and Engineering, Nanyang Technological University, Nanyang Avenue, Singapore, 639798, - - 2014
Lead free perovskite solar cells based on a CsSnI3 light absorber with a spectral response from 950 nm is demonstrated. The high photocurrents noted in the system are a consequence of SnF2 addition which reduces defect concentrations and hence the background charge carrier density.
Caselli Derek D ASU Nanophotonics Lab, Arizona State University , Tempe, Arizona 85287, United - - 2014
Nanomaterials such as semiconductor nanowires have unique features that could enable novel optoelectronic applications such as novel solar cells. This paper aims to demonstrate one such recently proposed concept: Monolithically Integrated Laterally Arrayed Multiple Band gap (MILAMB) solar cells for spectrum-splitting photovoltaic systems. Two cells with different band gaps were ...
Salem Abdelhakim A Department of Medicine, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland; Department of Oral Pathology, University of Helsinki, Helsinki, - - 2014
Oral lichen planus (OLP) is an autoimmune disease characterized by a band-like T-cell infiltrate below apoptotic epithelial cells and degenerated basement membrane. We tested the hypothesis that the high-affinity histamine H4 receptors (H4 Rs) are downregulated in OLP by high histamine concentrations and proinflammatory T-cell cytokines. Immunohistochemistry and immunofluorescence staining, ...
Mavrova Anelia Ts AT University of Chemical Technology and Metallurgy, 8 Kliment Ohridski Blvd., 1756 Sofia, Bulgaria. Electronic address: - - 2014
Some new thieno[2,3-d]pyrimidin-4(3H)-ones containing 1,2,4-triazole and 1,3,4-thiadiazole moiety were synthesized using thieno[2,3-d]pyrimidin-3(4H)-yl)acetohydrazides as precursors in order to determine their cytotoxicity. Compounds 5, 7-8 and 10-18 were evaluated for their cytotoxical effect on four cancer cell lines: human colorectal cancer cell line HT-29, breast cancer cells MDA-MB-231, cervical cancer cells HeLa, ...
Zhang Xinru X Department of Mechanical Engineering and §Department of Civil and Environmental Engineering, University of Hawaii at Manoa , Honolulu, Hawaii 96822 United - - 2014
Cell sorting is an important screening process in microbiology, biotechnology, and clinical research. Existing methods are mainly based on single-cell analysis as in flow cytometric and microfluidic cell sorters. Here we report a label-free bulk method for sorting cells by differentiating their characteristic surface free energies (SFEs). We demonstrated the ...
Vemavarapu Lakshmi L From the Department of Pathology, University of Louisville, Louisville, Kentucky (Drs Vemavarapu, Czyszczon, J. C. Parker, and J. R. Parker); the Department of Hematology and Oncology, Indiana University Simon Cancer Center, Indianapolis (Dr Wagner); and the Department of Neurosurgery, Norton Neuroscience Institute, Louisville, Kentucky (Dr - - 2014
We report a case of an intraventricular tumor with features of atypical central neurocytoma with a sarcomatous component in a 44-year-old woman who presented with headaches and vomiting. Magnetic resonance imaging revealed a 3.4-cm lobulated enhancing mass in the occipital horn of the left lateral ventricle, and the patient subsequently ...
Sheik-Khalil Enas - - 2014
Standardized techniques to detect HIV-neutralizing antibody responses are of great importance in the search for an HIV vaccine. Here, we present a high-throughput, high-content automated plaque reduction (APR) assay based on automated microscopy and image analysis that allows evaluation of neutralization and inhibition of cell-cell fusion within the same assay. ...
Zuo Lijian L Department of Materials Science and Engineering, University of Washington, Seattle, USA; State Key Laboratory of Silicon Materials, MOE Key Laboratory of Macromolecular Synthesis and Functionalization, Zhejiang University, Hangzhou, 310027, P. R. - - 2014
A high-performance parallel tandem solar cell employing ultra-thin Ag as the intermediate anode is demonstrated, which comprises a semitransparent front sub-cell and a microcavity assisted back sub-cell. In addition to the extended optical field as a result of the tandem architecture, the prominent microcavity resonance formed in the back sub-cell ...
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