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Results 301 - 350 of 1926
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Vellinga Else C - - 2009
Pseudobaeospora aphana, characterized by a brownish pileus with a lilac sheen, yellowish lamellae, a cutis of narrow hyphae on a subpellis of relatively wide and short cells, absence of cheilocystidia and color changes in KOH, and abundant clamp connections, is described as new. It was discovered during the Jan 2007 ...
Yu Diana - - 2009
Retinal Müller glial cells, in addition to providing homeostatic support to retinal neurons, have been shown to engage in modulation of neuronal activity and regulate vasomotor responses in the retina, among other functions. Calcium-mediated signaling in Müller cells has been implicated to play a significant role in the intracellular and ...
Do Kee Hun - - 2009
Lignans are major constituents of plant extracts and have important pharmacological effects on mammalian cells. Here we showed that pinoresinol-4,4'-di-O-beta-D-glucoside (PDG) from Valeriana officinalis induced calcium mobilization and cell migration through the activation of lysophosphatidic acid (LPA) receptor subtypes. Stimulation of mouse embryo fibroblast (MEF) cells with 10 microM PDG ...
Asano-Miyoshi Misaki - - 2009
Taste signal is received in taste buds and transmitted via sensory afferent nerves to the brainstem. Although a signaling pathway involving phospholipase C-beta2 has been shown to transduce taste signals of bitterness, sweetness and umami in taste receptor cells (Type II cells), these taste receptor cells appear to be different ...
Okubo Tadashi T Department of Cell Biology, Duke University Medical Center, Durham, North Carolina, USA. - - 2009
The epithelium of the mouse tongue and soft palate consists of at least three distinct epithelial cell populations: basal cells, keratinized cells organized into filiform and fungiform papillae, and taste receptor cells present in tight clusters known as taste buds in the fungiform and circumvallate papillae and soft palate. All ...
Rigat Brigitte - - 2009
Recently, inhibition of L-type Ca(2+) channels, using either Diltiazem or Verapamil, has been reported to partially restore mutant glucocerebrosidase activity in cells from patients with Gaucher disease homozygous for the N370S or L444P alleles, as well as cells from patients with two other lysosomal storage diseases. It was hypothesized that ...
Wang Hong H Monell Chemical Senses Center, Philadelphia, Pennsylvania 19104, - - 2009
Vertebrate taste buds undergo continual cell turnover. To understand how the gustatory progenitor cells in the stratified lingual epithelium migrate and differentiate into different types of mature taste cells, we sought to identify genes that were selectively expressed in taste cells at different maturation stages. Here we report the expression ...
Sato Toshihide - - 2009
A gap junction blocker, 18beta-glycyrrhetinic acid (beta-GA), increased the membrane resistance of Ia, Ib and II/III cells of frog taste disk by 50, 160, and 300 M Omega, respectively, by blocking the gap junction channels and hemichannels. The amplitudes of gustatory depolarizing potentials in the disk cells for 4 basic ...
Carrithers Michael D - - 2009
Voltage-gated sodium channels initiate electrical signaling in excitable cells such as muscle and neurons. They also are expressed in non-excitable cells such as macrophages and neoplastic cells. Previously, in macrophages, we demonstrated expression of SCN8A, the gene that encodes the channel NaV1.6, and intracellular localization of NaV1.6 to regions near ...
Patel G P - - 2009
Calcium sensitivity of petrosal ganglion neurons (PGNs) to chemical stimuli with and without PC-12 cells in co-culture instead of glomus is not known- the idea being that two types of unusual cells could form synapse and provide a model for studies of chemotransduction. Calcium levels in the PGNs were measured ...
Lin Yi-Wen - - 2009
BACKGROUND: While neural systems are known to respond to chemical and electrical stimulation, the effect of mechanics on these highly sensitive cells is still not well understood. The ability to examine the effects of mechanics on these cells is limited by existing approaches, although their overall response is intimately tied ...
Gibson Elizabeth A - - 2009
In tandem: Employing a molecular dyad and a cobalt-based electrolyte gives a threefold-increase in open-circuit voltage (V(OC)) for a p-type NiO device (V(OC) = 0.35 V), and a fourfold better energy conversion efficiency. Incorporating these improvements in a TiO(2)/NiO tandem dye-sensitized solar cell (TDSC), results in a TDSC with a ...
Ichikawa Hideki - - 2009
Salivary gland acinar cells secrete large amounts of water and electrolytes, where aquaporins (AQPs) are thought to be involved in the secretion. In the present study, we investigated expression/localization of AQP6, and the anion transporting properties of AQP6 in mouse parotid acinar cells. RT-PCR, western blotting and immunohistochemical analyses revealed ...
Lepple-Wienhues Albrecht - - 2009
To facilitate automated patch clamp measurements of ion channels in cells, the development of an all-glass Chiptip pipette is reported that may be combined with the previously described Flip-the-Tip technology. A single measurement requires less than 50 cells, and the addition of drugs for screening can be limited to very ...
Cutz Ernest - - 2009
In pulmonary neuroepithelial bodies (NEB), presumed airway chemoreceptors, classical NADPH oxidase (gp91 phox, NOX2) is co-expressed with O(2) sensitive K(+) channels (K(+)O(2)) and functions as an O(2) sensor. Here we examined related NADPH oxidase homologues "novel oxidases "(NOX 1, 3&4) and their possible involvement in O(2) sensing. For immunolocalization we ...
Kubikova I - - 2009
BACKGROUND AIMS: Microvesicles (MV) shed from the plasma membrane of eukaryotic cells, including human embryonic stem cells (hESC), contain proteins, lipids and RNA and serve as mediators of cell-to-cell communication. However, they may also contain immunogenic membrane domains and infectious particles acquired from xenogenic components of the culture milieu. Therefore, ...
Papke Roger L RL Department of Pharmacology and Therapeutics, University of Florida College of Medicine, Gainesville, Florida, USA. - - 2009
Voltage-clamp techniques are typically used to study the plasma membrane proteins, such as ion channels and transporters that control bioelectrical signals. Many of these proteins have been cloned and can now be studied as potential targets for drug development. The two approaches most commonly used for heterologous expression of cloned ...
Wang Yi-Ying YY Department of Computer Science and Information Engineering, National Cheng Kung University, Tainan, Taiwan, - - 2009
Nerve cell segmentation is important for better understanding of the connections between broken nerves. In this paper, we propose a registration-based segmentation to improve the segmentation from a series of microscopic image sequence. A global iterative closest point (ICP) registration is first employed to find the corresponding cells between neighboring ...
Cifuentes, L.
Two- and three-compartment copper electrowinning (EW) cells based on reactive electrodialysis (RED) have been studied. The catholyte was cupric sulphate and the anolyte was ferrous sulphate, both dissolved in sulphuric acid. Copper mesh cathodes and graphite bar anodes have been used. The effects of cell current density, temperature, electrolyte recirculation ...
Krause Martin - - 2009
Bursaria truncatella is a giant ciliate. Its volume of 3 x 10(7)microm(3) and a sedimentation rate of 923microm s(-1) would induce the cell to rapidly sink to the bottom of a pond unless compensating mechanisms exist. The upward swimming behaviour of a cell population (negative gravitaxis) may be either a ...
Chen Jen-Jeng - - 2009
Both pilot and laboratory scale experiments are conducted to compare the effect of ozone and permanganate preoxidation on algae removal by alum coagulation. Both appropriately dosed preoxidants are shown to be beneficial to algae coagulation removal. This may be attributed to a decrease in cell stability; however, overdosing may cause ...
Matsumura Shigenobu - - 2009
A recent study has demonstrated that the G-protein coupled receptor GPR120 is expressed in the taste bud cells in rats. In this study, we have identified the types of taste cell that express GPR120 in C57/BL6 mice. Double immunostaining for GPR120 and the markers of type II taste cells (phospholipase-Cbeta2 ...
Huang Yijen A YA Department of Physiology and Biophysics, and Program in Neuroscience, University of Miami School of Medicine, Miami, Florida 33136, - - 2008
ATP and serotonin (5-HT) are neurotransmitters secreted from taste bud receptor (type II) and presynaptic (type III) cells, respectively. Norepinephrine (NE) has also been proposed to be a neurotransmitter or paracrine hormone in taste buds. Yet, to date, the specific stimulus for NE release in taste buds is not well ...
Camilleri J - - 2008
AIM: To evaluate the biocompatibility of a group of new potential dental materials and their eluants by assessing cell viability. METHODOLOGY: Calcium sulpho-aluminate cement (CSA), calcium fluoro-aluminate cement (CFA) and glass-ionomer cement (GIC; Ketac Molar), used as the control, were tested for biocompatibility. Using a direct test method cell viability ...
Noguchi Chisato - - 2008
The effect of isoliquiritigenin (ISL), a component of licorice, on the voltage-dependent, ultra-rapidly activating delayed-rectifier K(+) current (IKur) was examined in H9c2 cells, a cell-line derived from rat cardiac myoblasts. IKur was recorded using the whole-cell patch clamp method with a pipette solution containing 140 mM K(+). Depolarizing voltage pulses ...
Kim Byung Joo - - 2008
Ca2+ and Mg2+ have a fundamental role in many cellular processes and ion channels are involved in normal physiologic processes and in the pathology of various diseases. The aim here was to show that the presence and potential role of transient receptor potential melastatin 7 (TRPM7) channels in the growth ...
Qin Yu-Mei - - 2010
Taste buds consist of four kinds of cells which have distinct characteristics and play different roles in recognizing chemical compounds contained in foodstuffs. In this study we describe a procedure for separating viable taste bud cells from the fungiform papillae in mice. After sacrifice with CO(2), the mouse tongue was ...
Masgrau Roser - - 2009
In neurogenesis, little is known about signal transduction pathways upstream of gene expression however, mounting evidence suggests that calcium release from internal stores plays a critical role. We have previously demonstrated that BM88 is a neuronal lineage-specific regulator of cell cycle exit and differentiation; we now report a link between ...
Thivierge, Daniel P.
A charging and equalizing method for a battery having a control computer in a charging system in communication with a plurality of module processors. Charging and equalization pauses periodically for voltage measurement by the module processors. The control computer determines when to equalize battery cells in the modules based on ...
Mizuno M - - 2008
AIM: The effect of calcium ions on dental pulp cells was examined and the mechanism of dentine bridge formation by calcium hydroxide was investigated. METHODOLOGY: Human dental pulp cells were treated with high concentration of calcium or magnesium ions for 24 h and fibronectin gene expression was measured by the ...
Fulcher M L - - 2009
Immortalization of human bronchial epithelial (hBE) cells often entails loss of differentiation. Bmi-1 is a protooncogene that maintains stem cells, and its expression creates cell lines that recapitulate normal cell structure and function. We introduced Bmi-1 and the catalytic subunit of telomerase (hTERT) into three non-cystic fibrosis (CF) and three ...
Takano Koji - - 2009
CONTEXT: The GHRH-protein kinase A (PKA) signalling pathway is essential for cell proliferation and GH synthesis/secretion in somatotrophs. An inactivating mutation of PRKAR1A is one of the causes of somatotrophinoma in Carney complex (CNC). The basal PKA activity of somatotroph adenoma cells from CNC has not been evaluated because of ...
Leñero Bardallo, J.A.
J.A. Leñero-Bardallo, T. Serrano-Gotarredona, B. Linares-Barranco. A Calibration Tehnique for Very Low Current and Compact Tunable Neuromorphic Cells. Application to 5-bit 20nA DACs, IEEE Trans. Circuits and Systems, Part-II: Brief Papers, vol. 55, nº 6, pp 522-526, june 2008
Brenner Tanja - - 2008
The rate of aldosterone synthesis by adrenal glomerulosa cells relies on the selective permeability of the glomerulosa cell to K(+) ions. In rodent and bovine adrenal glomerulosa cells, this background potassium current is provided by a two-pore loop potassium (K2P) channel: largely TASK-3 in the rat and TREK-1 in the ...
Dhingra Anuradha A Department of Neuroscience, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104-6058, - - 2008
Retinal ON bipolar cells make up about 70% of all bipolar cells. Glutamate hyperpolarizes these cells by binding to the metabotropic glutamate receptor mGluR6, activating the G-protein G(o1), and closing an unidentified cation channel. To facilitate investigation of ON bipolar cells, we here report on the production of a transgenic ...
Roberts, Craig Dane
cAMP is a second messenger in a variety of chemosensory receptors, including taste buds and glucose-sensitive pancreatic beta-cells. cAMP is modulated during taste transduction, yet the significance of cAMP changes and the taste cell types in which they occur (Type I glial-like; Type II Receptor; Type III Presynaptic) remain unclear. ...
McCombs Janet E JE Department of Chemistry and Biochemistry, University of Colorado, UCB 215, 76 Chemistry, Boulder, CO 80309-0215, - - 2008
Genetically encoded calcium indicators (GECIs) allow researchers to measure calcium dynamics in specific targeted locations within living cells. Such indicators enable dissection of the spatial and temporal control of calcium signaling processes. Here we review recent progress in the development of GECIs, highlighting which indicators are most appropriate for measuring ...
Potapova Irina A - - 2008
The need to regenerate tissue is paramount, especially for the heart that lacks the ability to regenerate after injury. The urinary bladder extracellular matrix (ECM), when used to repair a right ventricular defect, successfully regenerated some mechanical function. The objective of the current study was to determine whether the regenerative ...
Maleckar Mary M MM Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD 21218, - - 2008
In the mammalian heart, myocytes and fibroblasts can communicate via gap junction, or connexin-mediated current flow. Some of the effects of this electrotonic coupling on the action potential waveform of the human ventricular myocyte have been analyzed in detail. The present study employs a recently developed mathematical model of the ...
Wang Jiawei - - 2009
Lithium ions stimulate the Wnt signaling pathway and the authors previously demonstrated that lithium enhances the proliferation of tissue cultured human mesenchymal stem cells. The aim of this study was to prepare and characterize a calcium phosphate/lithium coating by means of electrolytic deposition. It was hypothesized that the hybrid coatings ...
Platz, R.
In the present paper, the authors discuss the application of amorphous p–i–n solar cells containing i-layers which are deposited at high substrate temperatures as top cells in amorphous silicon/microcrystalline silicon tandem (“micromorph”) solar cells. Increasing the substrate temperature for the deposition of intrinsic a-Si : H results in a reduced ...
Habela Christa W CW Department of Neurobiology, Center for Glial Biology in Medicine, University of Alabama at Birmingham, Birmingham, Alabama 35294, - - 2008
Although most brain cells are postmitotic, small populations of progenitor or stem cells can divide throughout life. These cells are believed to be the most likely source for primary brain malignancies including gliomas. Such tumors share many common features with nonmalignant glial cells but, because of their insidious growth, form ...
Meier, Johannes
Recently, we have demonstrated that intrinsic hydrogenated microcrystalline silicon, as deposited by the very high frequency glow-discharge technique, can be used as the active layers of p–i–n solar cells. Our microcrystalline silicon represents a new form of thin film crystalline silicon that can be deposited (in contrast to any other ...
Xu Ying Y Department of Neuroscience, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA. - - 2008
PCP2, a member of the GoLoco domain-containing family, is present exclusively in cerebellar Purkinje cells and retinal ON bipolar cells. Its function in these tissues is unknown. Biochemical and expression system studies suggest that PCP2 is a guanine nucleotide dissociation inhibitor, although a guanine nucleotide exchange factor has also been ...
Wasner Ulrike - - 2008
This study investigates the impact of intrinsic currents on early neural development. A rat striatal ST14A cell line immortalized by SV40 large T antigen was employed as a model system because these cells act as multipotent neural progenitors when maintained at a permissive temperature of 33 degrees C. The whole-cell ...
Meier, Johannes
Hydrogenated microcrystalline silicon prepared at low temperatures by the glow discharge technique is examined here with respect to its role as a new thin-film photovoltaic absorber material. XRD and TEM characterisations reveal that microcrystalline silicon is a semiconductor with a very complex morphology. Microcrystalline p–i–n cells with open-circuit voltages of ...
Mizuguchi, Jin
One of the most critical issues in the development of fuel cells is the use of costly platinum as the catalyst for the dissociation of H2 into protons (H+). Furthermore, the reserve of platinum is also limited. We present here a non-platinum method for dissociating H2 into protons using high-dielectric ...
Olsen Michelle L ML Department of Neurobiology & Center for Glial Biology in Medicine, The University of Alabama Birmingham, Birmingham, Alabama 35294-0021, - - 2008
Astrocytes and oligodendrocytes are characterized by a very negative resting potential and a high resting permeability for K(+) ions. Early pharmacological and biophysical studies suggested that the resting potential is established by the activity of inwardly rectifying, Ba(2+) sensitive, weakly rectifying Kir channels. Molecular cloning has identified 16 Kir channels ...
Meier, J.
Complete µc-Si:H <i>p-i-n</i> solar cells have been prepared by the very high frequency glow discharge method. Up to now, intrinsic µ<i>c</i>-Si:H has never attracted much attention as a photovoltaic active material. However, an efficiency of 4.6% and remarkably high short circuit current densities of up to 21.9 mA/cm<sup>2</sup> due to ...
Yamanaka Yuko - - 2008
Ten pairs of protrusions, called accessory lobes (ALs), exist at the lateral sides of avian lumbosacral spinal cords. Histological evidence has shown that neurons are present in AL and behavioral evidence suggests that AL acts as a sensory organ of equilibrium during bipedal walking. However, there is little functional evidence ...
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