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Borassi Cecilia C Instituto de Fisiología, Biología Molecular y Neurociencias (IFIBYNE-CONICET), Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Buenos Aires, - - 2015
Pollen tubes elongate by tip growth toward the ovule to deliver the sperm cells during fertilization. Since pollen tubes from several species can be grown in vitro maintaining their polarity, pollen tube growth is a suitable model system to study cell polarity and tip growth. A. thaliana pollen tubes germinated ...
Comai Glenda G Stem Cells and Development, Department of Developmental & Stem Cell Biology, URA CNRS 2578, Institut Pasteur, 25 rue du Dr. Roux, 75015 Paris, - - 2014
The myogenic regulatory genes Myf5, Mrf4, Myod, and Myogenin likely arose by gene duplications during evolution, presumably to address the more demanding requirements of the vertebrate body plan. Two cell lineages were proposed to be regulated independently by Myf5 and Myod to safeguard against tissue failure. Here we report severe ...
Courtot Mélanie M Molecular Biology and Biochemistry Department, Simon Fraser University, Burnaby, BC V5A 1S6, - - 2014
Finding one or more cell populations of interest, such as those correlating to a specific disease, is critical when analyzing flow cytometry data. However, labelling of cell populations is not well defined, making it difficult to integrate the output of algorithms to external knowledge sources. We developed flowCL, a software ...
Bao Jianqiang J Department of Physiology and Cell Biology, University of Nevada Reno School of Medicine, Reno, Nevada, United States of - - 2014
As a member of the large Ran-binding protein family, Ran-binding protein 9 (RANBP9) has been suggested to play a critical role in diverse cellular functions in somatic cell lineages in vitro, and this is further supported by the neonatal lethality phenotype in Ranbp9 global knockout mice. However, the exact molecular ...
Greene James M JM Department of Mathematics and Center for Scientific Computation and Mathematical Modeling (CSCAMM), University of Maryland, College Park, MD - - 2014
Intratumoral heterogeneity has been found to be a major cause of drug resistance. Cell-to-cell variation increases as a result of cancer-related alterations, which are acquired by stochastic events and further induced by environmental signals. However, most cellular mechanisms include natural fluctuations that are closely regulated, and thus lead to asynchronization ...
Allena R R Arts et Metiers ParisTech, LBM, 151 Bd de l'hôpital, 75013, Paris, France, - - 2014
Collective cell migration plays a fundamental role in many biological phenomena such as immune response, embryogenesis and tumorigenesis. In the present work, we propose a reaction-diffusion finite element model of the lateral line primordium migration in zebrafish. The population is modelled as a continuum with embedded discrete motile cells, which ...
Szymanski Daniel B DB Purdue University, Department of Botany and Plant Pathology, United States; Purdue University, Department of Biological Sciences, United States. Electronic address: - - 2014
Leaves are the primary organs for photosynthesis, and their angle, size, and timing of deployment determine the light capture efficiency of the canopy. Therefore, leaf development is an important trait in both natural and managed populations. In dicot leaves, the spatial and temporal patterns of cell division and expansion are ...
Sehgal Anita A Department of Botany, Miranda House, University of Delhi, Delhi, 110007, India, - - 2014
Reduced female gametophyte. Angiosperms are characterized by the phenomenon of double fertilization with Podostemaceae as an exception that appears to extend to the entire family. Our earlier work demonstrated the cause of failure of double fertilization and ascertained the occurrence of single fertilization in Dalzellia zeylanica (Tristichoideae, Podostemaceae). In continuation ...
Vachias Caroline C GReD Laboratory, UMR CNRS 6293 - Clermont Université - INSERM U1103, Faculté de Médecine, Place Henri Dunant, 63000 Clermont-Ferrand, - - 2014
Organs often need to coordinate the growth of distinct tissues during their development. Here, we analyzed the coordination between germline cysts and the surrounding follicular epithelium during Drosophila oogenesis. Genetic manipulations of the growth rate of both germline and somatic cells influence the growth of the other tissue accordingly. Growth ...
Niedojadło Katarzyna K Department of Cell Biology, Faculty of Biology and Environment Protection, Nicolaus Copernicus University, Lwowska 1, 87-100, Toruń, Poland, - - 2014
The composition of homogalacturonans (HGs) in the ovule and the female gametophyte cell walls was shown to be rearranged dynamically during sexual reproduction of H. orientalis. In angiosperms, homogalacturonans (HGs) play an important role in the interaction between the male gametophyte and the pistil transmitting tract, but little is known ...
Farias T O TO Programa de Pós-graduação em Zoologia de Vertebrados, Pontifícia Universidade Católica de Minas Gerais, Avenida Dom José Gaspar, 500, 30535-610, Belo Horizonte, MG, - - 2014
Yellowish myotis, Myotis levis, is a seasonal, epididymal sperm-storing Neotropical vespertilionid. In the dry season, males show simultaneous testis regression and sperm storage in cauda epididymis, enabling them to mate during this season. In this study, we investigated seasonal variations in body mass, diameter and height of seminiferous tubules and ...
Gawriluk Thomas R TR Department of Biology, University of Kentucky, Lexington, KY - - 2014
Autophagy is an important cellular process that serves as a companion pathway to the ubiquitin-proteasome system to degrade long-lived proteins and organelles to maintain cell homeostasis. Although initially characterized in yeast, autophagy is being realized as an important regulator of development and disease in mammals. Beclin1 (Becn1) is a putative ...
Ferguson Megan A MA Department of Chemistry, SUNY New Paltz, 1 Hawk Drive, New Paltz, NY - - 2014
Bdellovibrio bacteriovorus is a Gram-negative predator of other Gram-negative bacteria. Interestingly, Bdellovibrio bacteriovorus 109J cells grown in co-culture with Escherichia coli ML 35 prey develop into a spatially organized two-dimensional film when located on a nutrient-rich surface. From deposition of 10 μL of a routine cleared co-culture of B. bacteriovorus ...
King Benedict B Department of Zoology, University of Cambridge, Downing Street, Cambridge, U.K., CB2 3EJ. Electronic address: - - 2014
Malpighian tubules (MpTs) are the major organ for excretion and osmoregulation in most insects. MpT development is characterised for Drosophila melanogaster, but not other species. We therefore do not know the extent to which the MpT developmental programme is conserved across insects. To redress this we provide a comprehensive description ...
Rangarajan Sunil S Department of Medicine, Division of Nephrology, Nephrology Research and Training Center, University of Alabama at Birmingham, Birmingham, - - 2014
DNA label-retention, or retention of a thymidine analog, is a characteristic of slow cycling cells and has been used to identify stem cells in several organ systems. Recent findings have demonstrated inconsistent localization of label-retaining cells (LRCs) in the kidney. Differences in the dose and timing of administration of deoxyuridine, ...
Sebbagh Michael M CRCM, "Equipe labellisée Ligue Contre le Cancer", Inserm, U1068, Marseille F-13009, France; Institut Paoli-Calmettes, Marseille F-13009, France; CNRS, UMR7258, Marseille F-13009, France; Aix-Marseille University, F-13284 Marseille, France. Electronic address: - - 2014
Planar cell polarity or PCP refers to a uniform cellular organization within the plan, typically orthogonal to the apico-basal polarity axis. As such, PCP provides directional cues that control and coordinate the integration of cells in tissues to build a living organism. Although dysfunctions of this fundamental cellular process have ...
Jin Huiqin H Zhou Pei-Yuan Center for Applied Mathematics, MOE Key Laboratory of Bioinformatics, Tsinghua University, Beijing 100084, - - 2014
In this paper, we study the role of autophagy in yeast cell population dynamics in response to starvation by a mathematical model based on the logistic growth model. We analytically study the boundedness of solutions, and the existence and stability of equilibrium states under general biologically acceptable assumptions. Finally, we ...
Schaum C Elisa CE Institute of Evolutionary Biology, University of Edinburgh, Ashworth Laboratories, West Mains Road, Edinburgh EH9 3JF, UK - - 2014
Under global change, populations have four possible responses: 'migrate, acclimate, adapt or die' (Gienapp et al. 2008 Climate change and evolution: disentangling environmental and genetic response. Mol. Ecol. 17, 167-178. (doi:10.1111/j.1365-294X.2007.03413.x)). The challenge is to predict how much migration, acclimatization or adaptation populations are capable of. We have previously shown ...
Vanacker Julie J Pôle de Recherche en Gynécologie, Institut de Recherche Expérimentale et Clinique, Université Catholique de Louvain, 1200 Brussels, - - 2014
Our aim is to develop an artificial ovary allowing survival and growth of isolated follicles and ovarian cells, to restore fertility in women diagnosed with pathologies at high risk of ovarian involvement. For this, alginate beads containing isolated preantral follicles and ovarian cells were autografted to immunocompetent mice. One week after ...
Ugalde Unai U Department of Applied Chemistry, Faculty of Chemistry, University of the Basque Country, Manuel Lardizabal Ibilbidea, 3 20018, Donostia-San Sebastian, Spain, - - 2014
The mycelium is an organised cellular network that develops according to a functionally coherent plan. As it expands, the mycelium is capable of modulating the relative abundance of different cell types to suit the prevailing environmental conditions. This versatile pattern of multicellular development involves sophisticated environmental sensing and intercellular communication ...
El Cheikh R R CNRS UMR 5208, Institut Camille Jordan, Université Lyon 1, 43 blvd. du 11 novembre 1918, F-69622 Villeurbanne cedex, France; DRACULA Inria Grenoble Rhône-Alpes, Montbonnot F-38322, - - 2014
The circadian clock and the cell cycle are two tightly coupled oscillators. Recent analytical studies have shown counter-intuitive effects of circadian gating of the cell cycle on growth rates of proliferating cells which cannot be explained by a molecular model or a population model alone. In this work, we present ...
Klauzinska Malgorzata M Mouse Cancer Genetics Program, Center for Cancer Research, Frederick, MD 21702, - - 2014
Cripto-1 (CR-1)/Teratocarcinoma-derived growth factor1 (TDGF-1) is a cell surface glycosylphosphatidylinositol (GPI)-linked glycoprotein that can function either in cis (autocrine) or in trans (paracrine). The cell membrane cis form is found in lipid rafts and endosomes while the trans acting form lacking the GPI anchor is soluble. As a member of ...
Defaye Arnaud A Technologies Avancées pour le Génome et la Clinique (TAGC), UMR 1090 INSERM, CNRS-France, Aix Marseille Université, Parc Scientifique de Luminy, Case 928, 163 Avenue de Luminy, 13288, Marseille cedex 09, - - 2014
The Hox family of transcription factors defines cell identity along the A/P axis of animal body plan by modulating expression of distinct sets of target genes in a tissue specific manner. Identifying such tissue specific target genes is indispensable if one wants to understand how Hox proteins mediate their context ...
Liu Junli J School of Biological and Biomedical Sciences, Durham University Durham, - - 2014
Hydrodynamics, cell wall and ion dynamics are all important properties that regulate pollen tube growth. Currently, the two main pollen tube growth models, the cell wall model and the hydrodynamic model do not appear to be reconcilable. Here we develop an integrative model for pollen tube growth and show that ...
Sintes Eva E Department of Limnology and Oceanography, University of Vienna Vienna, - - 2014
The trophic interactions between bacteria and their main predators, the heterotrophic nanoflagellates (HNFs), play a key role in the structuring and functioning of aquatic microbial food webs. Grazing regulation of bacterial communities, both of biomass and community structure, have been frequently reported. Additionally, bottom-up responses of the HNF at the ...
Yuelling Larra W LW Cancer Biology Program, Fox Chase Cancer Center, Temple University Health - - 2014
Microdissection is a novel technique that can isolate specific regions of a tissue and eliminate contamination from cellular sources in adjacent areas. This method was first utilized in the study of Nestin-expressing progenitors (NEPs), a newly identified population of cells in the cerebellar external germinal layer (EGL). Using microdissection in ...
Dugenne Mathilde M Aix Marseille Université, Université de Toulon, CNRS/INSU, IRD, Mediterranean Institute of Oceanography, UM 110 Marseille, - - 2014
Phytoplankton is a key component in marine ecosystems. It is responsible for most of the marine primary production, particularly in eutrophic lagoons, where it frequently blooms. Because they are very sensitive to their environment, the dynamics of these microbial communities has to be observed over different time scales, however, assessment ...
Lieder Sarah S Institute for Biochemical Engineering, University of Stuttgart, Allmandring 31, Stuttgart, - - 2014
Population heterogeneity occurring in industrial microbial bioprocesses is regarded as a putative effector causing performance loss in large scale. While the existence of subpopulations is a commonly accepted fact, their appearance and impact on process performance still remains rather unclear. During cell cycling, distinct subpopulations differing in cell division state ...
Capuco Anthony V AV Bovine Functional Genomics Laboratory, US Department of Agriculture, Agricultural Research Service, Beltsville, Maryland 20705; email: - - 2013
Mammary glands are crucial to the reproductive strategy of mammals, and the milk of domesticated ruminants serves as an important source of nutrients for the human population. The majority of mammary gland development occurs postnatally, and the mammary gland undergoes cyclical periods of growth, differentiation, lactation, and regression that are ...
Westhorpe Frederick G - - 2012
The composition and structure of centromeric nucleosomes, which contain the histone H3 variant CENP-A, is intensely debated. Two independent studies in this issue, in yeast and human cells, now suggest that CENP-A nucleosomes adopt different structures depending on the stage of the cell cycle.
Wieland Markus - - 2012
In most approaches, personalized medicine requires time- and cost-intensive characterization of an individual's genetic background in order to achieve the best-adapted therapy. For this purpose, cell-based drug delivery offers a promising alternative. In particular, synthetic biology has introduced the vision of cells being programmable therapeutic production facilities that can be ...
Holmberg Johan - - 2012
Various studies have demonstrated that somatic differentiated cells can be reprogrammed into other differentiated states or into pluripotency, thus showing that the differentiated cellular state is not irreversible. These findings have generated intense interest in the process of reprogramming and in mechanisms that govern the pluripotent state. However, the realization ...
Anderson Kimberly L - - 2012
Viable methanogens have been detected in dry, aerobic environments such as dry reservoir sediment, dry rice paddies and aerobic desert soils, which suggests that methanogens have mechanisms for long-term survival in a desiccated state. In this study, we quantified the survival rates of the methanogenic archaeon Methanosarcina barkeri after desiccation ...
Shiomi Daisuke - - 2011
Cells lacking rodZ are not only defective in cell shape, but also in cell growth at low temperatures. Cold-sensitive growth was suppressed by a mutation of ispA without recovery from the round shape, and the mutation improved cell growth of the wild-type at low temperature.
Navarta L G LG Area de Tecnología Química y Biotecnología, Facultad de Química Bioquímica y Farmacia, Universidad Nacional de San Luis, San Luis, - - 2011
The aim of the present study was to evaluate and compare freezing and freeze-drying treatments for conserving Rahnella aquatilis (BNM 0523) with the goal to achieve an adequate commercial formulation of this biocontrol agent. The effect of several protective agents, rehydration media and freezing temperatures on the viability and functional ...
Begum Shahanara - - 2011
The cold stability of microtubules during seasons of active and dormant cambium was analyzed in the conifers Abies firma, Abies sachalinensis and Larix leptolepis by immunofluorescence microscopy. Samples were fixed at room temperature and at a low temperature of 2-3°C to examine the effects of low temperature on the stability ...
Mizuno Nobuyuki - - 2011
Common wheat is an allohexaploid species originating from a naturally occurring interspecific cross between tetraploid wheat and the diploid wild wheat Aegilops tauschii Coss. Artificial allopolyploidization can produce synthetic hexaploid wheat. However, synthetic triploid hybrids can show four types of hybrid growth abnormalities: types II and III hybrid necrosis, hybrid ...
Ernst Joachim F - - 2011
In fungi, the cell wall is a scaffold, an armor and an environmental gate. Sugar polymers including protein-O- or N-linked glycosyl chains or polysaccharides such as glucan or chitin are essential components to maintain cell wall functions. We describe mechanisms in the human fungal pathogen Candida albicans, by which the ...
Whitaker Ragnhild D - - 2011
Bacterial communication via quorum sensing has been extensively investigated in recent years. Bacteria communicate in a complex manner through the production, release, and reception of diffusible low molecular weight chemical signaling molecules. Much work has focused on understanding the basic mechanisms of quorum sensing. As more and more bacteria grow ...
Lynch Andrew L - - 2011
Significant interest exists in the application of trehalose, which has low permeability to the phospholipid bilayer, as a non-toxic intracellular cryopreservative for mammalian cells. Introduction of between 8±3mM and 266±22mM trehalose into human erythrocytes using the membrane permeabilizing polymer PP-50 allowed investigation of the relationship between intracellular trehalose concentration, pre-freeze ...
Yi Song - - 2011
Like MTL-heterozygous (a/α) cells, white MTL-homozygous (a/a or α/α) cells of Candida albicans, to which a minority of opaque cells of opposite mating type have been added, form thick, robust biofilms. The latter biofilms are uniquely stimulated by the pheromone released by opaque cells and are regulated by the mitogen-activated ...
Lorentzen Anna A Institute of Cancer Research, Cancer Research UK, Cancer Research UK Tumour Cell Signalling Unit, 237 Fulham Road, London SW3 6JB, - - 2011
Melanoma cells can switch between an elongated mesenchymal-type and a rounded amoeboid-type migration mode. The rounded 'amoeboid' form of cell movement is driven by actomyosin contractility resulting in membrane blebbing. Unlike elongated A375 melanoma cells, rounded A375 cells do not display any obvious morphological front-back polarisation, although polarisation is thought ...
Bai Seoung-Jai - - 2011
The oxygen evolution of single cells was investigated using a nano-probe with an ultra-micro electrode (UME) in a submicron sized system in combination with a micro-fluidic system. A single cell was immobilized in the micro-fluidic system and a nano-probe was inserted into the cytosolic space of the single cell. Then, ...
Li Ming G - - 2011
Biofabrication that incorporates living cells to manufacture various bioproducts is often carried out at different temperatures as the process demands. In the process, cells are subjected to mechanical forces, which may damage cells if the forces reach a certain level. Previous studies have shown that the cell damage is mainly ...
Zanni Karen L - - 2011
Aim: The purpose of this paper is to review the techniques and implications of laser capture microdissection (LCM) to isolate tissue and DNA of interest using breast biopsy tissue as an example. Background: Tissues are a heterogeneous mix of different cell types, and molecular alterations are often specific to a ...
Han Yoo Jeong - - 2011
Pseudogenes are considered nonfunctional genomic artifacts of catastrophic pathways. Recent evidence, however, indicates novel roles for pseudogenes as regulators of gene expression. We tested the functionality of myosin light chain kinase pseudogene (MYLKP1) in human cells and tissues by RT-PCR, promoter activity, and cell proliferation assays. MYLKP1 is partially duplicated ...
Shao Wei - - 2011
Hierarchical anatase TiO(2) nanoplates with tunable shell structure were developed as the novel planar scattering layer in dye-sensitized solar cells, showing improved cell performance due to the enhanced light harvesting capability.
Moal Vanessa Liévin-Le - - 2011
The Secreted autotransporter toxin, Sat, which belongs to the subfamily of serine protease autotransporters of Enterobacteriaceae (SPATEs), acts as a virulence factor in extraintestinal and intestinal pathogenic strains of Escherichia coli. We observed that HeLa cells exposed to the cell-free culture supernatant of recombinant strain AAEC185(Sat) containing the Sat toxin ...
Plodinec Marija - - 2011
The contribution of the intermediate filament (IF) network to the mechanical response of cells has so far received little attention, possibly because the assembly and regulation of IFs are not as well understood as that of the actin cytoskeleton or of microtubules. The mechanical role of IFs has been mostly ...
Ettema Thijs J G - - 2011
In eukaryotic and bacterial cells, spatial organization is dependent upon cytoskeletal filaments. Actin is a main eukaryotic cytoskeletal element, involved in key processes such as cell shape determination, mechanical force generation and cytokinesis. We describe an archaeal cytoskeleton which forms helical structures within Pyrobaculum calidifontis cells, as shown by in ...
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