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Chitta Kasyapa S KS Department of Hematology and Oncology, Mayo Clinic, Jacksonville, FL 32224, USA. - - 2013
Understanding the biology of Waldenström macroglobulinemia is hindered by a lack of preclinical models. We report a novel cell line, RPCI-WM1, from a patient treated for WM. The cell line secretes human immunoglobulin M (h-IgM) with κ-light chain restriction identical to the primary tumor. The cell line has a modal ...
Kasuga Jun - - 2012
The supercooling capability of xylem parenchyma cells (XPCs) in boreal hardwood species differs depending not only on species but also season. In the present study, the roles of cell walls and intracellular contents in supercooling capability of XPCs were examined in three boreal hardwood species, Japanese beech, katsura tree and ...
Delgado Dolores - - 2012
Stomata are epidermal bi-celled structures that differentiate within special cell lineages initiated by a subset of protodermal cells. Recently, we showed that the Arabidopsis photomorphogenic repressor COP10 controls specific cell-lineage and cell-signaling developmental mechanisms in stomatal lineages. Loss-of-function cop10-1 mutant cotyledons and leaves produced (in the light and in the ...
Li Guocan - - 2012
We report the first case of Ru(ii) dipyrrinates employed as dyes in dye-sensitized solar cells. These complexes exhibit panchromatic light harvesting that results in significant DSSC current densities, rendering them promising for photovoltaic applications. Adjustment of the lowest excited state energy is required to boost the power conversion efficiency.
Sumaru Kimio - - 2012
As a powerful tool of cell screening and cell purification, we developed a novel method to kill adherent cells as cultured on a substrate by micro-projection of incoherent visible light. To kill the cells by the mild light irradiated by electrically controllable micro-projection systems currently available, we introduced the assist ...
Hernández-Franyutti Arlette - - 2012
We describe seasonal variations of the histology of the seminiferous tubules and efferent ducts of the tropical, viviparous skink, Mabuya brachypoda, throughout the year. The specimens were collected monthly, in Nacajuca, Tabasco state, Mexico. The results revealed strong annual variations in testicular volume, stages of the germ cells, and diameter ...
Berk Veysel - - 2012
In their natural environment, microbes organize into communities held together by an extracellular matrix composed of polysaccharides and proteins. We developed an in vivo labeling strategy to allow the extracellular matrix of developing biofilms to be visualized with conventional and superresolution light microscopy. Vibrio cholerae biofilms displayed three distinct levels ...
Sun Yubing Y Integrated Biosystems and Biomechanics Laboratory, University of Michigan, Ann Arbor, Michigan 48109, United - - 2012
Mechanical properties of the extracellular matrix (ECM) have profound effects on cellular functions. Here, we applied novel photosensitive polydimethylsiloxane (photoPDMS) chemistry to create photosensitive, biocompatible photoPDMS as a rigidity-tunable material for study of mechanoresponsive cellular behaviors. By modulating the PDMS cross-linker to monomer ratio, UV light exposure time, and postexposure ...
Johnson Alyssa E AE Department of Cell and Developmental Biology, Vanderbilt University, Nashville, Tennessee, - - 2012
Mitotic exit and cell division must be spatially and temporally integrated to facilitate equal division of genetic material between daughter cells. In the fission yeast, Schizosaccharomyces pombe, a spindle pole body (SPB) localized signaling cascade termed the septation initiation network (SIN) couples mitotic exit with cytokinesis. The SIN is controlled ...
Lim Wonbong - - 2012
Abstract Objective: The aim of this study was to examine the reactive oxygen species (ROS) that are dissipated by 635 nm irradiation, and the effect of 635 nm irradiation on ROS scavenging system. Background data: Intracellular ROS are produced in the form of superoxide anion by either nicotinamide adenine dinucleotide phosphate (NADPH) ...
Xiao Jian-Long - - 2012
We used a liquid-crystal spatial light modulator to project 473 nm light patterns surrounding a region of adherent cells and achieved an arbitrarily micropatterned cell culture. For a group of ∼60 cells, the cell boundaries fit the pattern of light within 15% deviation of the side length. We also demonstrated ...
Kim Chanhong - - 2012
Enhanced levels of singlet oxygen ((1)O(2)) in chloroplasts trigger programmed cell death. The impact of (1)O(2) production in chloroplasts was monitored first in the conditional fluorescent (flu) mutant of Arabidopsis thaliana that accumulates (1)O(2) upon a dark/light shift. The onset of (1)O(2) production is rapidly followed by a loss of ...
Victora Gabriel D - - 2012
Germinal centers (GCs) are sites of B-cell clonal expansion, hypermutation, and selection. GCs are polarized into dark (DZ) and light zones (LZ), a distinction that is of key importance to GC selection. However, the difference between the B cells in each of these zones in humans remains unclear. We show ...
Nomikou Nikolitsa - - 2012
Photodynamic therapy (PDT) is emerging as a treatment modality for the management of neoplastic disease. Despite considerable clinical success, its application for the treatment of deep-seated lesions is constrained by the inability of visible light to penetrate deeply into tissues. An emerging alternative approach exploits the fact that many photosensitisers ...
Westendorf Aron F - - 2012
Photoactivatable PtIV diazido complexes have unusual photobiological properties. We demonstrate here that trans,trans,trans-[PtIV(N3)2(OH)2(py)(NH3)] 3 is a potent photoactivated cytotoxin towards human cancer cells in culture, with an average IC50 value in 13 cell lines of 55 ± 28 µM after 30 min (0.12 mW/cm2) photoactivation with UVA light, although visible ...
Singh Shailendra P - - 2012
Fremyella diplosiphon modifies the pigment composition of its major light-harvesting complexes, i.e., phycobilisomes (PBS), and cell and filament morphology according to ambient light quality in a process termed complementary chromatic adaptation (CCA). The cells are red in color, rectangular-shaped, and filaments are longer under green light (GL), in contrast with ...
Miyake Takeo - - 2012
Similar to conventional electrolyte batteries, biofuel cells often need to be stacked in order to boost their single cell voltage (<1V) up to a practical level. Here, we report a laminated stack of biofuel cells that is composed of bioanode fabrics for fructose oxidation, hydrogel sheets containing electrolyte and fuel ...
Mishra Swati - - 2012
Hydrogels, containing yeast cells or fibroblast cells, were fabricated using blue light-induced polymerization technique. The cell-loaded prepolymer formulation was comprised of poly(ethyleneglycol) diacrylate (more than or equal to 50% v/v), 0.5 wt % Eosin Y and 0.5 wt % triethanolamine as the base oligomer, photo-initiator, and co-initiator, respectively. The two ...
Sheng Xia - - 2012
The intraovarian function of gonadally produced inhibin and activin has been extensively studied in experimental models for decades, yet their presence and function have been rarely reported in wild rodents. With our seasonal breeding model, the wild ground squirrel, we aimed to investigate the possible roles of these peptides in ...
Itoh Masahiko - - 2012
The organization of the apical junctional complex and its association with the cytoskeleton is essential for the function of epithelial cells. However, knowledge about the signaling pathways that regulate these processes is still fragmentary. Here we found that ARHGEF11, a member of the RGS-RhoGEF family, associates with tight junctions (TJs) ...
Tamai T Katherine - - 2012
A fundamental role of the circadian clock is to control biochemical and physiological processes such that they occur an optimal time of day. One of the most significant clock outputs from a clinical as well as basic biological standpoint is the timing of the cell cycle. Here we show that ...
Gallardo J J - - 2012
This paper presents a non-conventional methodology and an instrumental system to measure the effect of temperature on the photovoltaic properties of solar cells. The system enables the direct measurement of the evolution of open-circuit voltage and short-circuit current intensity in relation to a continuously decreasing temperature. The system uses a ...
Yang Qing - - 2012
An integrated system consisting of a carbon fiber-ZnO hybrid nanowire (NW) multicolor photodetector is driven by a microbial fuel cell (see picture; PMMA=poly(methyl methacrylate), E=electrode). The self-powered photodetector can detect at light levels of as little as nW cm(-2) intensity with a responsivity of more than 300 A W(-1) .
Fidopiastis Pat M - - 2012
Vibrio fischeri cells are the sole colonists of a specialized light organ in the mantle cavity of the sepiolid squid Euprymna scolopes. The process begins when the bacteria aggregate in mucus secretions outside the light organ. The cells eventually leave the aggregate, enter the light organ, and encounter a rich ...
Zhang Yunlin - - 2012
We investigated phytoplankton absorption properties of Lake Taihu, in the spring and summer of 2005 and 2006, and for 17 days studied laboratory cultures of Scenedesmus obliquus (chlorophyta) and Microcystis aeruginosa (cyanophyta) to determine the effect of phytoplankton community composition and cell size on the absorption properties. There were significant ...
Zimmerli Céline - - 2012
Stomatal opening and closing are driven by ion fluxes that cause changes in guard cell turgor and volume. This process is, in turn, regulated by environmental and hormonal signals, including light and the phytohormone abscisic acid (ABA). Here, we present genetic evidence that expression of PHO1 in guard cells of ...
Han Lei - - 2012
A new light-driven, membraneless and mediatorless glucose-air biofuel cell combining a TiO(2) nanotube photoanode with an enzyme-modified biocathode has been successfully constructed. Upon UV light illumination, the open-circuit voltage and the maximum power density of the cell reach 1.00 V and 47 μW cm(-2), respectively.
Jayadev Ranjay - - 2012
The actin cross-linking protein, α-actinin, plays a crucial role in mediating furrow ingression during cytokinesis. However, the mechanism by which its dynamics are regulated during this process is poorly understood. Here we have investigated the role of calcium sensitivity of α-actinin in the regulation of its dynamics by generating a ...
Yang Pei-Wen - - 2012
Photodynamic therapy (PDT) has been demonstrated to be an effective minimally invasive treatment modality for early esophageal cancer. However, the molecular action in esophageal cancer during PDT is hardly known. EGFR has been known to downregulate in various cancer cells during PDT. In this study, we investigated the effects of ...
Funaki Takashi - - 2012
Efficient light harvesting: Cyclometalated ruthenium complexes were synthesized and evaluated in a dye-sensitized solar cell as near-IR sensitizers. Tuning of the HOMO energy level by structural modifications of the ligand improved the conversion efficiency of the cells based on these complexes to up to 10.7 %.
Jiang Kun - - 2012
Guard cell actin reorganization has been observed in stomatal responses to a wide array of stimuli. However, how the guard cell signaling machinery regulates actin dynamics is poorly understood. Here, we report the identification of an allele of the Arabidopsis thaliana ACTIN-RELATED PROTEIN C2/DISTORTED TRICHOMES2 (ARPC2) locus (encoding the ARPC2 ...
Hayrabedyan Soren - - 2012
It is currently accepted that the Sertoli cells are proliferatively active only during the embryogenesis and early fetal development, seizing to divide after puberty, when the spermatogenic niche is prepared, and they become terminally differentiated. So far, only seasonal breeders from mammals have been reported as having season-dependent variations in ...
Wu Kuan-Lin - - 2012
Panchromatic Os(II) sensitizers for dye-sensitized solar cells (DSCs) were prepared. A DSC based on TF-52 showed promising performance characteristics: short-circuit photocurrent density J(SC) =23.3 mA cm(-2) , open-circuit photovoltage V(OC) =600 mV, fill factor (FF)=0.633 and power conversion efficiency η=8.85 % under AM 1.5G simulated one-sun irradiation.
Jensen Matthew B MB University of Wisconsin Department of - - 2012
Neural cell transplantation is a promising therapy for stroke, but rejection of human cells in animal models is an obstacle to furthering this research. Many antirejection strategies have been reported, but few comparison data are available. We asked if human neural cell grafts would have different survival or differentiation with ...
Wang Hong Hui - - 2012
Myosin light-chain kinase (MLCK) is a multi-domain protein with kinase and actin-binding domains, among others. Deficiency of MLCK expression in GBaSM-4 vascular smooth muscle cells enhanced cell proliferation rate and shortened cell doubling time. Transient transfection of the MLCK-deficient cells with cDNA constructs of either wild-type MLCK or its mutant ...
Nakayama-Ichiyama Shoko - - 2012
Abstract For differentiating reactive plasmacytosis from clonal plasma cell neoplasms such as plasma cell myeloma (PCM), it is important to determine the expression of the cytoplasmic light chain accurately. Through retrospective analysis, we studied the cytoplasmic kappa/lambda ratio of CD138-positive plasma cells in bone marrow from 50 PCM patients and ...
Ribaux Pascale - - 2012
OBJECTIVES: During implantation, human trophoblastic cells have to proliferate, migrate and invade pregnant uterus. A natural product of cruciferous vegetables, 3,3'-diindolylmethane (DIM), is known to induce some stress response genes (such as glucose-regulated protein 78 kDa (GRP78)) and to have anti-invasive and pro-apoptotic effects on tumor cells. Therefore, we have ...
Chen Tao - - 2012
Metal wires suffer from corrosion in fiber-shaped dye-sensitized solar cells (DSSCs). We report herein that stable, ultrastrong, and highly flexible aligned carbon nanotube fibers can be used not only as catalytic counter electrodes but also as conductive materials to support dye-loaded TiO(2) nanoparticles in DSSCs. The power conversion efficiency of ...
Mikulich Aliaksandr - - 2012
BACKGROUND: Blebbistatin is a new inhibitor of cell motility. It is used to study dynamics of cytokinesis machinery in cells. However, the potential of this inhibitor as an anticancer agent has not been studied so far. METHODS: Cytotoxicity of blebbistatin was evaluated in five human cell lines, FEMX-I melanoma, U87 ...
Wang Y - - 2012
The infiltration of glioma cells into adjacent tissue is one of the major obstacles in the therapeutic management of malignant brain tumours, in most cases precluding complete surgical resection. Consequently, malignant glioma patients almost invariably experience tumour recurrences. Within the brain, glioma cells migrate rapidly either amoeboidly or mesenchymally to ...
Moiz Syed Abdul - - 2012
A novel stamped hybrid solar cell was proposed using the stamping transfer technique by stamping an active PEDOT:PSS thin layer onto the top of silicon nanowires (SiNWs). Compared to a bulk-type counterpart that fully embeds SiNWs inside PEDOT:PSS, an increase in the photovoltaic efficiency was observed by a factor of ...
Delgado Dolores - - 2012
Stomatal development in Arabidopsis thaliana has been linked to photoreceptor-perceived light through several components of the photomorphogenic switch, whose lack of function is often seedling-lethal. CONSTITUTIVE PHOTOMORPHOGENIC 10 (COP10) is an important component of this switch, its loss of function producing stomatal clusters. Exploiting the reduced lethality of the cop10-1 ...
Islam M Nazrul - - 2012
The present study investigated effects of apoptosis observed during seasonal testicular regression in Japanese Jungle Crows. The study was conducted during January to June 2008, 2009. Testes from adults captured during non-breeding (January), prebreeding (February to mid-March), main-breeding (late March to early May), transition (mid-May to late May), and post-breeding ...
Battaglia Corsin - - 2012
Theory predicts that periodic photonic nanostructures should outperform their random counterparts in trapping light in solar cells. However, the current certified world-record conversion efficiency for amorphous silicon thin-film solar cells, which strongly rely on light trapping, was achieved on the random pyramidal morphology of transparent zinc oxide electrodes. Based on ...
Krishnamurthy M - - 2012
We demonstrate that the interaction of intense femtosecond light on a plain solid substrate can be substantially altered by a few micron layer coating of bacterial cells, live or dead. Using E. Coli cells, we show that at an intensity of 10<sup>16</sup>W cm<sup>-2</sup>, the bremsstraahlung hard x-ray emission (up to ...
Feng Tingting - - 2012
A single-layer graphene film was grown on copper foil by chemical vapor deposition and transferred onto a silicon-pillar-array (SPA) substrate to make a Schottky junction solar cell. The SPA substrate was specifically designed to suppress reflectance and enhance light absorption. The energy conversion efficiency of the prepared graphene/SPA solar cells ...
Wang Wei - - 2012
Overall performance of a thin film solar cell is determined by the efficiency of converting photons to electrons through light absorption, carrier generation, and carrier collection. Recently, photon management has emerged as a powerful tool to further boost this conversion efficiency. Here we propose a novel nanograting solar cell design ...
Kimura Mutsumi - - 2012
Sensitive kind of dye: Co-sensitization of the TiO(2) electrode using PcS15 and the dye D131 results in a dramatic enhancement of the photocurrent response for the entire visible-light region. This method provides a simple design for accessing dye-sensitized solar cells.
Lugo Katherine - - 2012
Stimulating cells by using light is a non-invasive technique that provides flexibility in probing different locations while minimizing unintended effects on the system. We propose a new way to make cells photosensitive without using genetic or chemical manipulation, which alters natural cells, in conjunction with Quantum Dots (QDs). Remote switching ...
Zhang Luhui - - 2012
Previous fiber-shaped solar cells are based on polymeric materials or dye-sensitized wide band-gap oxides. Here, we show that efficient fiber solar cells can be made from semiconducting nanostructures (e.g. CdSe) with smaller band-gap as the light absorption material. We directly grow a vertical array of CdSe nanowires uniformly around a ...
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