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Lee Hye Mi HM Department of Neurology, Korea University Guro Hospital, Korea University College of Medicine, Guro-dong Ro 148, Guro-gu, Seoul 152-703, Republic of - - 2014
Previous MRI studies have investigated cortical or subcortical grey matter changes in patients with Parkinson's disease (PD), yielding inconsistent findings between the studies. We therefore sought to determine whether focal cortical or subcortical grey matter changes may be present from the early disease stage. We recruited 49 untreated, early stage ...
Chevallier Justyna A JA Department of Pediatrics, Division of Child and Adolescent Neurology, University of Texas Health Science Center, Houston, Texas, - - 2014
Seizures constitute a frequent yet under-described manifestation of mitochondrial disorders (MDs). The aim of this study was to describe electroencephalography (EEG) findings and clinical seizure types in a population of children and adults with mitochondrial disease. Retrospective chart review of 165 records of children and adults with mitochondrial disease seen ...
Dearborn Jennifer L JL Johns Hopkins Hospital Bayview Medical Center, Baltimore, MD, - - 2014
A 41-year-old man, during a neurological consultation, reported "chin twitching" over a period of a week, which was diagnosed as intermittent perioral myoclonia. With only one tonic-clonic seizure seven years before, he had mentioned several episodes of chin twitching over the years. In the clinic, there were intermittent chin movements ...
Tachon Guillaume G 1AP-HP, Service d'Anesthésie-Réanimation, Hôpitaux Universitaires Paris-Sud, Université Paris-Sud, Hôpital de Bicêtre, Le Kremlin-Bicêtre, France. 2Microcirculation, Bioénergétique, Inflammation et Insuffisance Circulatoire Aiguë, Equipe Universitaire 3509, Paris VII-Paris XI-Paris XIII, Paris, France. 3Baker IDI Heart and Diabetes Institute, Melbourne, VIC, Australia. 4Hôpitaux Universitaires de Strasbourg, Service d'Anesthésie-Réanimation Chirurgicale, Hôpital de Hautepierre, Université de Strasbourg, Fédération de Médecine Translationnelle de Strasbourg (FMTS), Equipe d'accueil EA 3072 "Mitochondrie, stress oxydant et protection musculaire" Strasbourg, - - 2014
Microcirculatory dysfunction has been well reported in clinical studies in septic shock. However, no clinical studies have investigated microcirculatory blood flow behavior in hemorrhagic shock. The main objective of this study was to assess the time course of sublingual microcirculation in traumatic hemorrhagic shock during the first 4 days after ...
Mulay Sudhanshu B SB Division of Hematology/Oncology, University of Connecticut Health Center, Farmington, - - 2014
The use of hematopoietic progenitor cell (HPC) transplant has risen over the past two decades. A variety of adverse events (AEs) of varying severity have been noted during HPC infusions. These AEs have been associated with several factors such as the amount of dimethyl sulfoxide and white blood cells in ...
Virgili Annarosa A Department of Medical Sciences, Section of Dermatology, University of Ferrara, Ferrara, - - 2014
Background: Few reports have addressed the associations between clinical, demographic and historical variables of vulvar lichen sclerosus (VLS). Objective: To elaborate the prevalence and severity of signs and symptoms and to identify potential factors predicting the severity and course of VLS. Methods: A prospective cohort of 225 patients affected by ...
Wang Shiqi S Xijing Hospital of Digestive Diseases, Fourth Military Medical University, Xi'an, Shaanxi Province, - - 2014
The purpose of this study is to investigate the accuracy of currently used scoring systems in differentiating transient and persistent organ failure in patients with acute pancreatitis (AP). In this retrospective study, 127 consecutive patients with AP and organ failure were included. Patients were divided into transient and persistent organ ...
Aygun Dursun D Ondokuz Mayis University, Medical School, Department of Nurology, Samsun, Turkey. Electronic address: - - 2014
Studies documenting the association between rapid eye movement sleep behavior disorder (RBD) and motor subtypes in Parkinson's disease (PD) are rare. Our hypothesis is that RBD may be more severe in non-tremor dominant (NTD) patients with RBD than those tremor dominant (TD) with RBD. In this study, we investigated the ...
Deng Xiaofeng X Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, 100050, China, - - 2014
The asymmetry of tonsillar ectopia, syringomyelia, and clinical manifestations, and their correlations in adult Chiari I malformation (CIM) are seldom discussed. Clinical and imaging data of 104 consecutive adult patients with CIM and syringomyelia were retrospectively reviewed. A method was devised to quantify tonsillar and syrinx asymmetry. Correlations between the ...
Simoneau Tregony T Connecticut Children's Medical Center, Division of Pulmonary Medicine, Hartford, Connecticut, United States ; - - 2014
Rationale: Patients with cystic fibrosis (CF) have high rates of vitamin D insufficiency. The relation between vitamin D status and inflammation in patients with CF is poorly understood. Objectives: To determine the prevalence of vitamin D deficiency and insufficiency in a young CF population and to examine correlations between vitamin ...
Husar-Memmer Emma - - 2014
Hereditary hemochromatosis is a frequent disease in Caucasian populations. It leads to progressive iron overload in a variety of organs. The most common cause is the C282Y homozygous mutation in the HFE gene. The classical triad of skin hyperpigmentation, diabetes, and liver cirrhosis is nowadays rare but musculoskeletal symptoms are ...
Kumar Neeraj N Department of Neurology, Mayo Clinic, Rochester, MN, USA. Electronic address: - - 2014
Optimal functioning of the central and peripheral nervous system is dependent on a constant supply of appropriate nutrients. Particularly important for optimal functioning of the nervous system is cobalamin (vitamin B12). Cobalamin deficiency is particularly common in the elderly and after gastric surgery. Many patients with clinically expressed cobalamin deficiency ...
Seitz Jochen J Department of Child and Adolescent Psychiatry, Psychotherapy and Psychosomatics, University Hospital RWTH Aachen, - - 2014
Objective: Acute anorexia nervosa (AN) leads to reduced gray (GM) and white matter (WM) volume in the brain, which however improves again upon restoration of weight. Yet little is known about the extent and clinical correlates of these brain changes, nor do we know much about the time-course and completeness ...
Tramontani Ourania O ENT Surgeon, The Ipswich Hospital, Ipswich, United - - 2014
Background The aim of this prospective clinical study was to evaluate the clinical importance of Vestibular-Evoked Myogenic Potentials (VEMPs) in the assessment and differential diagnosis of otosclerosis and otologic diseases characterized by "pseudo-conductive" components. We also investigated the clinical appearance of balance disorders in patients with otosclerosis by correlating VEMP ...
Gupta Pradeep Kumar - - 2013
Structural imaging of the brain does not demonstrate any changes in a vast majority of patients with vitamin B12 deficiency, even in advanced stages. In this study, we aimed to assess and correlate the functional integrity of the brain fiber tracts using diffusion tensor tractography with neuropsychological examination in patients ...
Sipola S - - 2013
Severe intestinal mucosal damage and organ failure has been associated in experimental models. Our purpose was to determine whether there is any association between histopathological findings and postoperative mortality among ICU patients undergoing emergency colectomies for various illnesses. In a retrospective case control study, total colectomy specimens from 50 patients ...
Jones Nicholas P - - 2013
Abstract Purpose: To demonstrate the demography, anatomical, and diagnostic classification of patients with uveitis attending the Manchester Uveitis Clinic (MUC), a specialist uveitis clinic in the northwest of England, UK. Methods: Retrospective retrieval of data on a computerized database incorporating all new referrals to MUC from 1991 to 2013. Results: ...
Eltweri Amar M - - 2013
Sleeve gastrectomy has increased in popularity over the last five years and it is likely to supersede gastric banding. Nevertheless, it is unclear whether vitamin B12 supplementation is required after surgery. The aim of this short report is to identify any vitamin B12 deficiency and highlight the necessity of post ...
Liu Jixin - - 2013
To assess the longitudinal gray matter (GM) and white matter (WM) changes between repeated observations 1 year apart in a group of the early clinical stage of migraine patients without aura, and to explore the relationship of such structural changes with headache activity, we studied patients newly diagnosed with episodic ...
Palamarchuk Iryna - - 2013
Background: A significant number of patients admitted to hospital after acute ischemic stroke deteriorate clinically. Deterioration is generally noted within the first 48 h after stroke onset. The mechanisms leading to this deterioration are not fully understood. Summary: One potential cause of this deterioration may be altered or impaired autonomic ...
Barry Peter J - - 2013
Clinical trials have revealed that Ivacaftor significantly reduces sweat chloride in patients with cystic fibrosis who carry the G551D mutation. This finding has been incorporated into the commissioning guidelines in the UK with a sweat chloride reduction of 30% or below 60 mmol/L, specified as the main criteria for continued ...
Wasielewska A A Anna Wasielewska, MD, Department of Neurology, Jagiellonian University Medical College, 3 Botaniczna St., Krakow 31-503, Poland, e-mail: - - 2013
Background and purpose: Tremor accompanies some poly-neuropathies, but its prevalence and its clinical and electrophysiological manifestations are not well known. The aim of the study was to assess the occurrence and characteristics of hand tremor in patients with polyneuropathy of different origins, as well as relations between the occurrence of ...
Javed A P AP Department of Oral Medicine and Radiology, Annoor Dental College, Muvattupuzha, Kerala, - - 2013
Epidermolysis bullosa (EB) is an inherited disorder, which is characteristically presented as skin blisters developing in response to minor injury. Junctional variety of EB is also associated with enamel hypoplasia. Amelogenesis imperfecta presents with abnormal formation of the enamel both in deciduous and permanent dentition. This article describes a previously ...
Fornito Alex A Monash Clinical and Imaging Neuroscience Laboratory, School of Psychology and Psychiatry, Monash University, Clayton, Victoria, Australia2Centre for Neural Engineering, University of Melbourne, Parkville, Victoria, Australia3NICTA Victorian Research Laboratory, University of Melbourne, Parkville, Victoria, Australia4Melbourne Neuropsychiatry Centre, Department of Psychiatry, University of Melbourne and Melbourne Health, Parkville, Victoria, - - 2013
Dysregulation of corticostriatal circuitry has long been thought to be critical in the etiology of psychotic disorders, although the differential roles played by dorsal and ventral systems in mediating risk for psychosis have been contentious. To use resting-state functional magnetic resonance imaging to characterize disease-related, risk-related, and symptom-related changes of ...
Bissolotti Luciano - - 2013
The aim of this study was to describe the disease-related sagittal balance changes in relation to the sacropelvic morphology of PD patients with different durations of disease. Thirty-one consecutive Parkinson's disease patients (26 males, 5 females; age 55-83 years) participated in the cross-sectional study. The clinical assessment included: Hoehn Yahr score; ...
Charalampakis Georgios - - 2013
The aim of this study was to identify sites at risk for future progression, during 2 yr of maintenance, in patients with chronic periodontitis (CP), based on longitudinal clinical and microbiological monitoring. At baseline (2003), clinical and microbiological features were recorded in 50 patients with CP. Two microbial samples were obtained ...
Alvis-Miranda Hernando Raphael HR Faculty of medicine, Universidad de Cartagena, Cartagena de Indias, - - 2013
Cerebral sinus venous thrombosis (CSVT) is a rare phenomenon that can be seen with some frequency in young patients. CSVT is a multifactorial condition with gender-related specific causes, with a wide clinical presentation, the leading causes differ between developed and developing countries, converting CSVT in a condition characterized by a ...
Roiz-Santiáñez R - - 2013
Schizophrenia is a chronic brain disorder associated with structural brain abnormalities already present at the onset of the illness. Whether these brain abnormalities might progress over time is still under debate. The aim of this study was to investigate likely progressive brain volume changes in schizophrenia during the first 3 ...
Andela Cornelie D - - 2013
Patients with long-term remission of Cushing's disease (CD) have persistent psychological and cognitive impairments. It is unknown whether, and to what extent, these impairments are accompanied by structural abnormalities in the brain. We aim to investigate structural changes in the brain in a sample of patients with predominantly long-term remission ...
Freeston Je - - 2013
Arthritis activity assessments in PsA have traditionally relied on tender and swollen joint counts but in rheumatoid arthritis, multiple studies have demonstrated sub-clinical inflammation using modern imaging. The aim of this study was to compare CE (clinical examination) and ultrasound (US) findings in an early psoriatic arthritis (PsA) cohort. 49 ...
Egger Karl - - 2013
Erythropoietin (EPO) has received growing attention because of its neuroregenerative properties. Preclinical and clinical evidence supports its therapeutic potential in brain conditions like stroke, multiple sclerosis, and schizophrenia. Also, in Friedreich ataxia, clinical improvement after EPO therapy was shown. The aim of this study was to assess possible therapy-associated brain ...
Tuntiyatorn Lojana - - 2013
Stroke is a clinically syndrome of a sudden onset of neurological deficit in a vascular cause. Stroke mimics is the non-vascular disorders with stroke-like clinical symptoms. It is important to distinguish true stroke from mimics since treatment plan may differ To determine the incidence of the stroke mimics and identify ...
Ceponis Arnoldas - - 2013
Objective. To investigate usefulness of point-of-care hand, and wrist joint ultrasound examination in patients with established rheumatoid arthritis (RA). Methods. Fifty-one RA patients were evaluated using clinical disease activity measures, grey scale and power Doppler (PD) ultrasound. Agreement between ultrasound and clinical findings, and its impact on physician's confidence and ...
Rance Karen - - 2013
Vitamin D deficiency and asthma share risk factors. Epidemiologists suggest that the U.S. prevalence of Vitamin D deficiency has increased as a result of the Westernization of culture and less time spent outdoors. Numerous studies support a patient's Vitamin D deficiency as a contributing cause to increased asthma symptoms, lower ...
Chin D - - 2013
Background: Correlating patient perception of nasal obstruction sidedness to causative anatomy is important in surgical planning. The accuracy of patient-perceived asymmetry of nasal obstruction, as regards objective measures, is described. Methods: Cross-sectional study of patients undergoing nasal airflow assessment. Unilateral obstruction was assessed using visual analogue scale scores and anterior ...
Hey Christiane - - 2013
Swallowing disorders are common in patients after surgery for head and neck cancer. The clinical assessment of oral and laryngopharyngeal abilities is widely used as a dysphagia assessment tool in this patient group, despite a lack of research. The goal of this study was to assess the predictability of clinical ...
Karli R - - 2013
The aim of this study was to investigate the possible association between otoacoustic emission (OAE) values and cochlear function in patients with vitamin B12 deficiency and no evidence of symptomatic hearing loss. Two groups were studied: Group 1: patients with vitamin B12 deficiency; Group 2: a matched control group of ...
Lancioni Giulio E - - 2013
Abstract Objective: Assessing the effects of response-related music stimulation versus general (response-unrelated) music stimulation on positive participation of 11 new patients with Alzheimer's disease. Method: The patients were functioning in the severe and low-moderate ranges of the disease. Positive participation included behaviors such as, singing or rhythmic movements and smiles. ...
Mavrommati K - - 2013
Vitamin B12 deficiency can manifest with haematological, gastrointestinal and neuropsychiatric signs. The neuropsychiatric symptoms may be concurrent or precede the other symptoms. The reported case is a clinical case of delirium due to vitamin B12 deficiency in a female vegetarian patient. The patient was treated with vitamin B12 supplementation. Initially, ...
Kelly Anne-Maree - - 2013
The aim of this study was to compare changes in arterial and venous pH and pCO2 in patients undergoing noninvasive ventilation and having serial blood gases to assess ventilatory function. This was a prospective observational study of patients with acute respiratory distress. The outcome of interest was agreement in change ...
Galletti F - - 2013
To evaluate seizures as first clinical manifestation of brain arteriovenous malformations (AVMs), in relation to angioarchitectural features of these vascular anomalies. We performed a prospective observational study, collecting records of patients with AVMs consecutively admitted to the Neurological and Neurosurgery Units of Perugia University and to the Neurosurgery Unit of ...
Fernández-Torre José L - - 2013
To describe the causes and outcome of adult patients with preserved electroencephalographic activity despite clinical findings suggesting brain death (BD), and its impact on organ donation. Retrospective study of the clinical and electroencephalography (EEG) data of all adult patients admitted to our hospital between January 2001 and December 2011 in ...
Kim Seung Young - - 2013
An accumulation of pigment deposits on mucosa, called melanosis or pseudomelanosis, of the small bowel is observed infrequently during endoscopic examination. We describe 6 cases of small bowel pseudomelanosis; the possible etiology of which was chronic iron intake. We observed numerous brown spots in duodenum, jejunum, and terminal ileum during ...
Greco A - - 2013
Mobilization and postural changes of patients with cognitive impairment are standard clinical practices useful for both psychic and physical rehabilitation process. During this process, several physiological signals, such as Electroen-cephalogram (EEG), Electrocardiogram (ECG), Photopletysmography (PPG), Respiration activity (RESP), Electrodermal activity (EDA), are monitored and processed. In this paper we investigated ...
Pontin José Carlos Baldocchi JC Department of Orthopedics and Traumatology of Universidade Federal de São Paulo - Escola Paulista de Medicina. São Paulo, SP, - - 2013
Evaluate the static positioning of the scapula on the rib cage in healthy subjects by means of clinical and radiographic evaluation to assess inter-examiner reliability of clinical examination and verify the reliability of this evaluation method compared to the radiographic examination. We selected 30 adult individuals of both sexes with ...
Karam Chafic - - 2013
We studied 25-hydroxyvitamin D (vitamin D) levels in patients with amyotrophic lateral sclerosis (ALS) and the effect of vitamin D supplementation. Vitamin D levels were checked in 37 consecutive patients with ALS. Demographic data, vitamin D supplementation, change in Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS-R) score, and side effects ...
Mac-Way Fabrice - - 2013
Vitamin D deficiency/insufficiency is significantly prevalent in chronic kidney disease. Data in the literature are however scarce about the effects of this deficiency on bone metabolism in hemodialysis (HD) patients. Moreover, it is still debated whether low vitamin D levels should be normalized in HD patients. In this paper, we ...
Dharampal Anoeshka S - - 2013
OBJECTIVE: To investigate the value of the calcium score (CaSc) plus clinical evaluation to restrict referral for CT coronary angiography (CTCA) by reducing the number of patients with an intermediate probability of coronary artery disease (CAD). METHODS: We retrospectively included 1,975 symptomatic stable patients who underwent clinical evaluation and CaSc ...
Carvalho Filomena Marino - - 2013
OBJECTIVE: Functional polyps and chronic endometritis are among the most common abnormalities seen in the endometrium of patients with implantation failures and recurrent miscarriages. In this study we describe morphological vascular changes in endometrial samples from asymptomatic infertile patients and their association with chronic endometritis and polyp. STUDY DESIGN: We ...
Ellerbrock Isabel - - 2013
PURPOSE OF REVIEW: The objective of this review is to give an overview of recent advances regarding structural changes and altered neural connectivity associated with chronic headache syndromes, focusing on migraine. RECENT FINDINGS: In conjunction with a recent boost of studies investigating exercise dependent neuroplasticity and reorganization of the brain, ...
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