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Robic Marie Angèle - - 2011
The prognosis of patients with chronic liver disease is to a great extent determined by the presence and degree of portal hypertension (PHT). Hepatic venous pressure gradient (HVPG) has been shown to be an accurate prognostic index in patients with cirrhosis. Transient elastography is a non-invasive procedure that assesses liver ...
Hassanein Tarek I - - 2011
PURPOSE OF REVIEW: Acute-on-chronic liver failure (ACLF), a syndrome precipitated by acute liver injury in patients with advanced cirrhosis, is associated with multiorgan dysfunction and high rates of mortality. Liver support systems have been developed in an attempt to improve survival of patients with ACLF by providing a bridge until ...
Piscaglia F - - 2011
PURPOSE: VirtualTouch is a new technique recently proposed to evaluate liver stiffness during B-mode ultrasonography. The goal of the present study was to analyze the diagnostic accuracy of VirtualTouch in the diagnosis of cirrhosis and its correlation with transient elastography (Fibroscan). MATERIALS AND METHODS: A total of 133 patients with ...
Song Jung-Soo - - 2011
So far, there was no report on the prevalence and clinical relevance of anti-Ro52 in primary Sjögren's syndrome (pSS) patients in Korea. In this study, we investigated the prevalence and the clinical relevance of anti-Ro52 in Korean patients with pSS. We retrospectively reviewed the medical records of 96 patients with ...
Hoffman Arthur - - 2011
To investigate the safety of consecutive mini-laparoscopy guided liver biopsies for the diagnosis and staging of liver diseases. In this study we retrospectively analyzed the safety of mini-laparoscopic liver biopsy performed in an endoscopy unit in 1071 patients. We measured the incidence of bleeding and evaluated the management and outcome ...
Wanninger Josef - - 2011
OBJECTIVE: Transforming growth factor-β1 (TGFβ1) is a short-lived immune suppressive and profibrotic protein. Itslatent precursor is relatively stable and may even protect from fibrosis. Latent TGFβ1 is synthesized by various tissues including the liver and portal, hepatic, andsystemic concentrations of latent TGFβ1 were determined in patients with liver cirrhosis and ...
Arnon Ronen - - 2011
Arnon R, Annunziato RA, Miloh T, Padilla M, Sogawa H, Batemarco L, Willis A, Suchy F, Kerkar N. Liver and combined lung and liver transplantation for cystic fibrosis: Analysis of the UNOS database. Pediatr Transplantation 2011. © 2011 John Wiley & Sons A/S. Abstract:  A proportion of patients with CF ...
Andersen Ellen Sloth - - 2011
Transient elastography (TE) is a noninvasive and well validated method for measurement of liver stiffness. The aim of this study was to use TE to evaluate whether patients with sustained virological response (SVR) have lower liver stiffness than patients with non-SVR after treatment for chronic hepatitis C (CHC). Patients with ...
Stefanescu Horia - - 2011
Splenomegaly in a common finding in liver cirrhosis that should determine changes in the spleen's density because of portal and splenic congestion and/or because of tissue hyperplasia and fibrosis. These changes might be quantified by elastography, so the aim of the study was to investigate whether spleen stiffness measured by ...
Yilmaz Yusuf - - 2011
Vascular endothelial growth factor A (VEGF) is a multifunctional cytokine affecting angiogenesis and vascular function. The biological activity of VEGF is modulated by its soluble receptor VEGFR-1 (sVEGFR-1). We explored the associations of VEGF and sVEGFR-1 concentrations with liver histology in patients with biopsy-proven nonalcoholic fatty liver disease (NAFLD). The ...
Abdel Ghaffar Tawhida Y - - 2011
Cockayne syndrome is a rare autosomal recessive neurodegenerative disease characterized by low-to-normal birth weight; growth failure; brain dysmyelination with calcium deposits, cutaneous photosensitivity; pigmentary retinopathy, cataract, and sensorineural hearing loss. To the best of our knowledge, cholestatic liver disease was not previously reported in these patients. To highlight the presence ...
Lee Hyun Jung - - 2010
Background and Aims: Transient elastography (TE) is useful for predicting the fibrosis stage, but it is unsatisfactory substitutes for liver biopsy, especially in patients with chronic hepatitis B (CHB). This study was performed to establish a reliable model for predicting significant fibrosis (SF) in patients with CHB. Methods: All CHB ...
Rey Johannes-W JW Institute for Pathology, University Hospital Cologne, Kerpener Str. 62, 50924 Cologne, - - 2010
To test the occurrence of the Pro12Ala mutation of the peroxisome proliferator-activated receptor-γ (PPARγ)2-gene in patients with non-alcoholic fatty liver disease (NAFLD) or alcoholic fatty liver disease (AFLD). DNA from a total of 622 specimens including 259 blood samples of healthy blood donors and 363 histologically categorized liver biopsies of ...
Wagener Gebhard - - 2011
Relative vasopressin deficiency, a contributor to vasodilatory septic shock, also may be a cause of the vasodilatory state in liver disease. This study assessed endogenous vasopressin levels in patients with liver disease and their hemodynamic response to exogenous vasopressin. A prospective, observational study. A single-center, tertiary hospital. Human subjects undergoing ...
Carey Elizabeth J - - 2010
The 6-minute walk distance (6MWD) is a simple test measuring global physical function. It is commonly used to predict mortality in patients with cardiac and pulmonary diseases, but it is also useful in assessing the functional status of patients with a variety of other medical conditions. We sought to determine ...
Athyros Vasilios G - - 2010
Long-term statin treatment reduces the frequency of cardiovascular events, but safety and efficacy in patients with abnormal liver tests is unclear. We assessed whether statin therapy is safe and effective for these patients through post-hoc analysis of the Greek Atorvastatin and Coronary Heart Disease Evaluation (GREACE) study population. GREACE was ...
Lewindon Peter J - - 2011
Cystic fibrosis liver disease (CFLD), which results from progressive hepatobiliary fibrosis, is an important cause of morbidity and mortality, but it is difficult to identify before portal hypertension (PHT) ensues. Clinical signs, serum alanine aminotransferase (ALT) levels, and ultrasound (US) are widely applied, but their value in predicting the presence ...
Lewindon Peter J - - 2010
Cystic fibrosis liver disease (CFLD), which results from progressive hepatobiliary fibrosis, is an important cause of morbidity and mortality, but it is difficult to identify before portal hypertension (PHT) ensues. Clinical signs, serum alanine aminotransferase (ALT) levels, and ultrasound (US) are widely applied, but their value in predicting the presence ...
Macêdo Liana Gonçalves - - 2010
To determine the occurrence of hepatopulmonary syndrome (HPS) in patients with cirrhosis who are candidates for liver transplantation; to compare demographic, clinical, laboratory, and spirometric characteristics, as well as echocardiography results, arterial blood gas analysis, and severity of liver disease between the groups of patients with and without HPS; and ...
Rolstad Sindre - - 2010
The concepts of brain and cognitive reserve stem from the observation that premorbid factors (e.g., education) result in variation in the response to brain pathology. Potential early influence of reserve on pathology, as assessed using the cerebrospinal fluid biomarkers total tau (t-tau) and amyloid-beta42, and cognition was explored in mild ...
Houben Paul H H - - 2010
OBJECTIVES: (1) To investigate the frequency of cascades of further diagnostic investigations and referrals after abnormal laboratory results in situations of low disease probability; (2) to investigate pretest and posttest determinants; and (3) to describe the cascades that occur. STUDY DESIGN AND SETTING: Prospective cohort study in primary care in ...
Hevia Oscar - - 2009
BACKGROUND: The correction of infraorbital volume loss with dermal fillers results in a natural, youthful, rested appearance. Defects in this facial region should be treated for optimal patient satisfaction. OBJECTIVE: This retrospective review describes large-scale use of injection of calcium hydroxylapatite (CaHA) and a technique for injection into the infraorbital ...
Qu Xiuli - - 2009
The successful implementation of open access scheduling requires the match of daily healthcare provider capacity and patient demand at the high level of total capacity and the low levels of individual capacities for different types of appointments. In this paper, we introduce 12 scheduling rules for determining the two-level provider ...
Constantinides Minas - - 2009
The business of rhinoplasty has undergone changes in keeping with increased competitive pressures locally, nationally, and internationally. Patient demands and progress in the field have abolished the "cookie-cutter" nose, with patients now requesting extensive discussions and predictions with computer photoimaging. The R-Factor Question and The D.O.S. Conversation are effective tools ...
Wilhelm D - - 2009
PURPOSE: The informed consent is a legal requirement prior to surgery and should be based on an extensive preoperative interview. Multimedia productions can therefore be utilised as supporting tool. In a prospective randomised trial, we evaluated the impact of an extended education on patients undergoing cholecystectomy. MATERIALS AND METHODS: For ...
Borgsteede Sander D - - 2009
PURPOSE: To examine what pain and adjuvant medication is prescribed in palliative care patients at home in The Netherlands. METHODS: In a nationwide, representative, prospective study in general practice in The Netherlands, prescribed medication was registered in 95 general practices with a listed population of 374 070 patients. The GPs ...
Nietert Paul J - - 2009
BACKGROUND: Despite the proven effectiveness of many medications for chronic diseases, many patients do not refill their prescriptions in the required timeframe. OBJECTIVE: Compare the effectiveness of 3 pharmacist strategies to decrease time to refill of prescriptions for common chronic diseases. RESEARCH DESIGN/SUBJECTS: A randomized, controlled clinical trial with patients ...
Lohr Kathleen N - - 2009
PURPOSE: Introduce and explore issues at an international conference about the use of patient-reported outcomes (PROs) in clinical practice. METHODS: Review of salient literature, clinical and personal experiences, conference presentations and discussions, and post-conference comments from outside experts. RESULTS: PROs (information from patients about a health condition and its management) ...
Chatfield Simon M - - 2009
Prevalence of dietary complementary and alternative medicine (CAM) and consultation with a CAM practitioner was examined in a cross-sectional study of 75 AS patients. Seventy one of 75 (94.7%) study participants reported previous or current CAM use. Among these AS patients, 44 (72.1%) reported dietary CAM use and 27 (36.0%) ...
Sinha S - - 2009
INTRODUCTION: The aim of this study was to assess the attitude and the preferences of patients towards the use of a chaperone during breast examination. PATIENTS AND METHODS: A two-part questionnaire was circulated among 204 consecutive new patients, attending both symptomatic breast and screened assessment clinics. RESULTS: A total of ...
Redman Barbara K - - 2008
Although patient education is central to the ethical practice of nursing, it can be practiced in an ethically contested or unethical way. It is sometimes used to: forward a societal goal the individual might not have chosen; assume that patients should learn to accommodate unjust treatment; exclude the views of ...
van Manen Janine - - 2008
Treatment selection in clinical practice is a poorly understood, often largely implicit decision process, perhaps especially for patients with personality disorders. This study, therefore, investigated how intake clinicians use information about patient characteristics to select psychotherapeutic treatment for patients with personality disorder. A structured interview with a forced-choice format was ...
Krane N Kevin - - 2009
Measuring actual practice behaviors of physicians, particularly as they relate to established clinical guidelines, is challenging. Standardized patients provide one method of collecting such data. To demonstrate the use of unannounced standardized patients in gathering data that may address adherence to guidelines in an office setting. Unannounced standardized patients (SPs) ...
Kristoffersen Agnete Egilsdatter - - 2008
BACKGROUND AND OBJECTIVES: Self-reported use of complementary and alternative medicine (CAM) among patients varies widely between studies, possibly because the definition of a CAM user is not comparable. This makes it difficult to compare studies. The aim of this study is to present a six-level model for classifying patients' reported ...
Montini Theresa - - 2008
OBJECTIVE: To develop a standard taxonomy for inpatient complaints that could be adopted in a wide array of health service institutions. DESIGN: A taxonomy was developed by merging the coding schemes from eight prior studies of patient complaints, and then by revising the received coding scheme in light of the ...
Edvardsson David - - 2009
BACKGROUND: The nursing literature is replete with articles on the function of clothing in preventing and controlling infections. However, although contemporary literature demonstrates intimate connections between clothing and identity, there is a lack of studies which illuminate the meanings associated with wearing patient clothing. OBJECTIVES: This study aimed to illuminate ...
Baillie Lesley - - 2009
BACKGROUND: Nurses have a professional duty to respect patients' dignity. There is a dearth of research about patients' dignity in acute hospital settings. OBJECTIVE: The study investigated the meaning of patient dignity, threats to patients' dignity, and how patient dignity can be promoted, in acute hospital settings. DESIGN: A qualitative, ...
Whittaker Paul G - - 2008
CONTEXT: Advance provision of emergency contraception increases the likelihood of its use, yet little is known about the factors that influence successful implementation of an advance provision policy in publicly funded family planning clinics. METHODS: Data on knowledge of, attitudes toward and use of emergency contraception were collected from 211 ...
Somville F J M P - - 2008
Until the no-fault law in Belgium (15/05/2007) comes in action on 01/01/2009 it will be a system of fault to prove. Therefore the informed consent stays a mean or not liability progress. At this moment it stays a problem for the surgeon when he has not given any information about ...
Makeham Meredith A B - - 2008
The Threats to Australian Patient Safety (TAPS) study collected 648 anonymous reports about threats to patient safety from a representative random sample of Australian general practitioners. These contained any events the GPs felt should not have happened and would not want to happen again, regardless of who was at fault ...
Hochman Ohad - - 2008
OBJECTIVE: The objective of this study was to assess the correlation between patients' view of the consultation and the assessment of an auditing physician on the same consultation. METHODS: A prospective study in military clinics was conducted. A board-certified family physician made a real-time semistructured assessment of the medical consultation. ...
Geller Berta M - - 2008
Rural populations as well as less educated people in the United States are less likely to receive colorectal cancer (CRC) screening than people living in urban areas and more educated people. We tested a computer tablet, Patient/Provider Communication Assistant (PPCA), which collected data, educated patients, and printed personalized notes to ...
van Weel-Baumgarten Evelyn - - 2008
Life style related risk factors have negative consequences for many health outcomes. Although preventive actions undertaken on a population level are effective, these actions do not reach the individuals who could benefit most. Family doctors could reach many of these individuals when they consult them for other reasons. Unfortunately time ...
Jones Rupert C M - - 2008
INTRODUCTION: The Lung Information Needs Questionnaire (LINQ) assesses, from the patient's perspective, their need for education. This questionnaire yields a total score and scores in six domains: disease knowledge, medicine, self-management, smoking, exercise and diet. The aim of this study was to assess the sensitivity of the LINQ to change ...
Doran Tim - - 2008
BACKGROUND: In the English pay-for-performance program, physicians use a range of criteria to exclude individual patients from the quality calculations that determine their pay. This process, which is called exception reporting, is intended to safeguard patients against inappropriate treatment by physicians seeking to maximize their income. However, exception reporting may ...
Mariotti Giuliano - - 2008
OBJECTIVE: There is a lack of standard methods for determining the clinical priority of patients referred by general practitioners (GPs) for specialist outpatient consultations. We introduced a system of progressive involvement by general practitioners and specialists with 80 diagnostic procedures. The aim of this study was to evaluate this new ...
Chitnis J - - 2008
OBJECTIVE: To determine whether daily board rounds in the emergency department (ED) alter patient management and whether they provide educational opportunities. METHOD: A prospective observational study of board rounds conducted in a small to medium-sized ED in the United Kingdom. Data were collected on changes made and educational events that ...
Bodner Stanley - - 2008
Patient care and management can present a significant source of stress for the practicing dentist. This article presents the various facets and underpinnings of stress, followed by an overview of the physiologic phenomena attending the classic stress response, with an examination of the interplay between the psychologic components of stress ...
Gould Mark - - 2008
Patient safety errors are often caused by the NHS being a "Tower of Babel", with many "languages" spoken. Staff "tribes" often focus on their own agendas, rather than on the patients' health. The National Patient Safety Campaign is aiming to make the topic a priority of staff, patients and carers.
Shah Amit - - 2008
INTRODUCTION: The benefits of a healthy lifestyle are well-known. However, translating such information into behavior change is challenging. We explored patient perception in regard to how frequently this information is being disseminated, whether it may alter patient behavior, and whether information tailored to race versus general information is desirable. METHODS: ...
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