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Green William W Department of Urology, Nottingham City Hospital , Nottingham , - - 2014
Abstract Objective.The aim of this study was to identify factors at presentation that can help to predict outcomes and guide subsequent management decisions in patients with acute on chronic retention. Material and methods. The medical notes of 187 consecutive patients presenting with urinary retention at two teaching hospitals between 2008 ...
Szeto Cheuk-Chun CC Carol and Richard Yu Peritoneal Dialysis Research Centre, Department of Medicine - - 2014
Residual renal function (RRF) is an important prognostic indicator in continuous ambulatory peritoneal dialysis (CAPD) patients. We determined the predictors of RRF loss in a cohort of incident CAPD patients. We reviewed the record of 645 incident CAPD patients. RRF loss is represented by the slope of decline of residual ...
Siddarth Manushi - - 2013
Chronic kidney disease (CKD) of unknown etiology represents about 16% of CKD patients in Indian subcontinents and 10% worldwide. The aetiology of CKD of unknown etiology remains unclear though epidemiological studies indicate the involvement of the environmental toxins. Organochlorine pesticides (OCPs) have been detected in general population in India. It ...
Shimizu Toru - - 2012
PURPOSE: To clarify whether the clinical profiles of patients with a history of urolithiasis ("stone formers") truly reflect those of patients who currently have renal stones ("stone carriers"). MATERIALS AND METHODS: 463 gout patients were investigated by helical computed tomography (CT), urolithiasis history, and relevant clinical parameters. RESULTS: 1) Nephrolithiasis ...
Yamashita Koji - - 2011
The purpose of this article is to explore the factors that contribute to the occurrence of cholesteatoma. We studied the size of the mastoid air cells and the tympanic cavity using high-resolution CT. Temporal bone CT scans of consecutive patients with unilateral cholesteatoma and healthy control subjects were retrospectively analyzed. ...
Elbeldi-Ferchiou Asma - - 2011
BACKGROUND: The mechanisms underlying the loss of self-tolerance in systemic lupus erythematosus (SLE) are incompletely deciphered. TGF-β plays a key role in self-tolerance demonstrated by the onset of a fatal autoimmune syndrome associated with lupus autoantibodies in mice lacking a functional TGF-β receptor. The present work aims to define whether ...
Ikezoe Takayuki - - 2011
Our study determined if Janus kinase 2 (JAK2) was activated in acute myelogenous leukemia (AML; n = 77, excluding acute promyelocytic leukemia) by immunohistochemistry (IHC) using a phosphor-specific antibody against JAK2. p-JAK2 was detectable in all cases, although its levels varied between patient samples (high levels, n = 31; low ...
Plaza José Antonio - - 2011
To describe clinical, radiographic, and morphologic findings in patients with IgG4-positive cells present on orbital biopsy specimens. Retrospective review (from January 1, 1993, through December 31, 2006) of patients with orbital biopsy specimens that excluded lymphoma; comparison of patients with and without IgG4-positive cells on immunostaining. Of 21 patients, 11 ...
Stathopoulos G P - - 2011
Hematologic paraneoplastic alternations may not be very common, but they have been observed in a small number of patients. Granulocytosis has been described in several malignancies and its common mechanism may be associated with granulocyte colony-stimulating factor (G-CSF) production by the tumor. High neutrophilia (150,000-240,000 white blood cell count) observed ...
Liu Julia J - - 2011
BACKGROUND: Epithelial gaps created by shedding of epithelial cells in the small intestine can be visualized by using confocal laser endomicroscopy (CLE). The density of epithelial gaps in the small bowels of patients with inflammatory bowel disease (IBD) and controls without IBD is unknown. OBJECTIVE: To determine whether the epithelial ...
Rusanova Iryna - - 2011
To analyze the frequency of the haplotypes of β-globin gene cluster in randomly selected patients with sickle cell disease (SCD), attended in the Children's Hospital of Panama. Five polymorphic sites in the β-globin gene cluster were analyzed by polymerase chain reaction (PCR) followed by restriction digestion and agarose gel electrophoresis ...
Ragheb Samia S Department of Neurology, Wayne State University, Detroit, MI 48201, USA. - - 2011
There is increasing evidence of B-cell involvement in the pathogenesis of multiple sclerosis (MS). B-cell activating factor (BAFF) has an essential role in B-cell homeostasis. The chemokine CXCL13 has an important role in the formation and maintenance of B-cell follicles. To measure BAFF and CXCL13 levels in the cerebrospinal fluid ...
Mahmoudi Mohammad Jafar - - 2011
Background: Atherosclerosis, a chronic inflammatory disease of the vessel wall, is characterized by local and systemic immune responses to a variety of antigens. Oxidized low-density lipoprotein (oxLDL) is considered as an important determining factor in the pathogenesis of atherosclerosis. Objective: The purpose of this study was to investigate the degree ...
Oguanobi N I - - 2011
The prognostic implications of P-wave dispersion in patients with a variety of cardiac disease conditions are increasingly being recognised. The relationship between P-wave dispersion and left ventricular function in sickle cell anaemia is unknown. This study was aimed at evaluating the relationship between P-wave dispersion and left ventricular function in ...
Sène Damien - - 2011
We conducted this study to characterize the relationship between primary Sjögren syndrome (pSS)-associated peripheral neuropathy (PN) and markers of B-cell monoclonal proliferation and chronic activation.The cohort included 120 consecutive patients presenting with definite pSS according to the American-European Consensus Group criteria. Serum markers of chronic B-cell activation included autoantibodies and ...
Goh Hyun-Gyung - - 2011
Undetectable BCR-ABL transcripts in patients with chronic myeloid leukemia (CML) should not be regarded as indicative of a cure, due to the sensitivity limit of current real-time quantitative polymerase chain reaction (RQ-PCR) technology. To demonstrate the feasibility of more sensitive approaches, 62 samples from 43 patients with CML were screened ...
Yamada Kenji - - 2011
We report four cases of exceptional follicular lymphoma (FL) showing marked monocytoid or plasmacytoid differentiation and tiny or indistinct follicles, mimicking marginal zone lymphoma or plasma cell neoplasm. The lymphoma of patient 2 had lymphoepithelial lesions. The lymphoma of patient 4, who had a history of typical FL, was composed ...
Kofler Sieglinde - - 2011
BACKGROUND:: Dendritic cells (DCs), regulators of innate and adaptive immunity, may play an important role in atherosclerosis. DC invasion was found in early atherosclerotic lesions. We aimed to characterize circulating DC gene expression in patients with different subsets of coronary artery disease (CAD). METHODS:: Peripheral blood mononuclear cells (PBMCs) were ...
Terry Emily N - - 2011
Imatinib inhibits the ABL tyrosine kinase and is effective for the treatment of chronic myeloid leukemia (CML). ABL activates GPx-1, an enzyme associated with protection against oxidative DNA damage and disease. Enzyme activity was assessed in sample pairs consisting of mononuclear cells obtained from patients before and after imatinib therapy. ...
Gertz Morie A - - 2011
It is not widely recognized that patients with amyloidosis may be associated with an IgM monoclonal protein. We reviewed the characteristics of 22 IgM amyloidosis patients seen at Mayo Clinic from 1989 through 2010 and uniformly treated with stem cell transplantation. IgM patients are older, have a higher prevalence of ...
Mugii Naoki - - 2011
Objective. Although findings of nail-fold capillary changes and reduced red blood cell velocity in SSc patients are well established, studies in adult-onset DM patients are scarce. Our objective was to assess the changes and red blood cell velocity in finger nail-fold capillaries using nail-fold video capillaroscopy (NVC) in patients with ...
Zhang Yan - - 2011
BACKGROUND: Th17/Treg was reported to play critical roles in immunoregulation, and its imbalance may lead to autoimmune diseases and allergic reactions. Information on Th17/Treg in cancer bearing hosts is still limited. METHODS: We examined the expression of IL-17, Foxp3 and IL-10 in uterine cervical cancer (UCC) patients, cervical intraepithelial neoplasia ...
Baker Joshua F - - 2011
Circulating endothelial progenitor cells (EPCs) are reduced in patients with systemic lupus erythematosus (SLE). A reduced number of EPCs are associated with the presence of atherosclerosis in other populations. We sought to determine whether the reduction in EPC numbers in SLE is dependent on the presence of advanced coronary artery ...
Zonghong Shao - - 2011
The objectives of the study were to investigate the number of myeloid dendritic cells (mDC) and plasmacytoid dendritic cells (pDC) present in peripheral blood mononuclear cells (PBMC) from severe aplastic anemia (SAA) patients before and after intensive immunosuppressive therapy (IST) and to assess the expression of co-stimulatory molecules (CD80, CD86, ...
Akatsuka Naoko - - 2011
OBJECTIVE: The aim of this study was to investigate the expression of CD23 (Fcɛ RII) in the lymph nodes (LNs) of patients with Kimura's disease (KD). METHODS: Expression of CD23 was examined immunohistochemically. The concentrations of soluble CD23 and titers of IgE in sera from patients with KD were studied ...
Teofili Luciana - - 2011
In this study we investigated whether neoplastic transformation occurring in Ph-negative Myeloproliferative Neoplasms (MPN) could involve also the endothelial cell compartment. We evaluated the level of endothelial colony forming cells (ECFC) in 42 patients (15 with polycythemia vera, 12 with essential thrombocythemia and 15 with primary myelofibrosis (PMF). All patients ...
Hus Iwona - - 2011
Immunotherapy with dendritic cells (DC) may constitute a new and advantageous option for patients with chronic myeloid leukemia (CML) who respond to therapy with tyrosine kinase inhibitors (TKI), but do not reach complete cytogenetic or molecular remission. In this study, we evaluated the immunophenotype of DC generated from monocytes (Mo-DC) ...
Herberth Marlis - - 2011
Little is known about the molecular factors that are altered in remitting bipolar disorder (BD) patients. We carried out proteome profiling of peripheral blood mononuclear cells (PBMCs) and serum from BD patients who were not experiencing mania or major depression (euthymia) compared to matched healthy controls using liquid chromatography-mass spectrometry ...
Groves Michael J - - 2011
The detection of Philadelphia-negative (Ph(neg)) cells with non-random karyotypic abnormalities after tyrosine kinase inhibitor (TKI) therapy of chronic myeloid leukaemia (CML) can be associated with myelodysplastic syndrome (MDS) or acute myeloid leukemia (AML). To our knowledge, however, there have been no studies on variables influencing the risk of MDS/AML in ...
Li Chunming - - 2011
Multiple myeloma (MM) is characterized by complex genetic and chromosomal abnormalities involving both numerical and structural aberrations, which have clinical prognostic value. The plasma cell labeling index (PCLI) is one of the most important prognostic factors in newly diagnosed MM, and indicates plasma cell proliferative capacity. In this study, we ...
Herberth Marlis - - 2011
Little is known about the molecular factors that are altered in remitting bipolar disorder (BD) patients. We carried out proteome profiling of peripheral blood mononuclear cells (PBMCs) and serum from BD patients who were not experiencing mania or major depression (euthymia) compared to matched healthy controls using liquid chromatography-mass spectrometry ...
Peng Fuhua - - 2010
Autologous peripheral hematopoietic stem cell transplantation (APHSCT) was performed to treat a patient with neuromyelitis optica. We observed that the patient achieved clinical remission after APHSCT during 12 months of follow-up. The patient improved on the expanded disability status scale neurologic assessment and the Scripps neurologic rating scale worksheet scores ...
Hannemann A A Department of Veterinary Medicine, University of Cambridge, Madingley Road, Cambridge CB3 0ES, - - 2011
Sickle cell disease (SCD) is one of the commonest severe inherited disorders, but specific treatments are lacking and the pathophysiology remains unclear. Affected individuals account for well over 250,000 births yearly, mostly in the Tropics, the USA, and the Caribbean, also in Northern Europe as well. Incidence in the UK ...
Fan Qing - - 2010
Changes in the fronto-striato-thalamo-cortical-circuit loop have been suggested in the pathogenesis of obsessive-compulsive disorder (OCD), and have been studied using (1)H magnetic resonance spectroscopy ((1)H MRS) with interesting findings. However, whether neural metabolites are abnormal in the medial prefrontal cortex in patients with OCD is unknown. The purpose of the ...
Yang Tao - - 2010
To explore the possible abnormal resting-state activity in patients with obsessive-compulsive disorder (OCD), the regional homogeneity (ReHo) of 22 pairs of patients and well-matched healthy controls was calculated. Compared with controls, the patients showed higher ReHo in the left anterior cingulate cortex, but lower ReHo in the left inferior temporal ...
Van Hauwaert Valérie - - 2010
A 20-year old man with ulcerative colitis (UC) and primary sclerosing cholangitis (PSC) was diagnosed with a rectal non-Hodgkin's lymphoma (NHL) at surveillance endoscopy while being in remission on infliximab therapy. Further staging identified a diffuse large B-cell NHL, EBV negative restricted to the rectal submucosa (stage IA). Until now, ...
de Leeuw Aart S - - 2010
Obsessive-compulsive disorder (OCD) is associated with deficits in inhibition mechanisms. This is reflected in reports showing impaired sensorimotor and sensory gating in OCD patients, as measured with prepulse inhibition (PPI) of the startle reflex and P50 suppression paradigms. However, most of the patients in these studies used medication and the ...
Jhung Kyungun - - 2010
Impaired recognition of facial expressions of disgust has been suggested for patients with obsessive-compulsive disorder (OCD). This study aimed to compare the perception of negative emotions by OCD patients and controls using both non-ambiguous and ambiguous facial expressions. Forty-one OCD patients and thirty-seven controls performed the computerised emotion perception task. ...
Provini F - - 2010
OBJECTIVE: We investigated the prevalence of nocturnal smoking (NS) in patients with RLS. METHODS: One hundred RLS patients living in Emilia-Romagna (Northern Italy) and 100 matched controls, randomly selected from the general population, underwent interviews for the presence of nocturnal smoking and for obsessive-compulsive traits, depression, excessive daytime sleepiness (EDS) ...
Bălănescu P - - 2010
Lupus erythematosus (LE) is an autoimmune inflammatory disease that involves many organs and systems. Immunological factors seem to play a key-role in LE pathogenesis. LE patients have T lymphocytes dysfunctions.Th17 is implicated in the pathogenesis of various autoimmune diseases like psoriasis, multiple sclerosis or rheumatoid arthritis. The purpose of this ...
Matsuo Koji - - 2010
Suicidality is a life-threatening symptom in patients with bipolar disorder (BD). Impulsivity and mood instability are associated with suicidality in mood disorders. Evidence suggests that gray and white matter abnormalities are linked with impulsivity in mood disorders, but little is known about the association between corpus callosum (CC) and impulsivity ...
Shim Geumsook - - 2009
BACKGROUND: Anterior cingulate cortex (ACC) abnormalities have been implicated consistently in the pathophysiology of obsessive-compulsive disorder (OCD), yet it remains unclear whether these abnormalities originated during early neurodevelopment. In this study, we examined the ACC sulcal/gyral patterns to investigate whether neurodevelopmental anomalies of the ACC were present in patients with ...
Atmaca Murad - - 2009
AIM: To date, despite possible neuroanatomical importance, no magnetic resonance spectroscopy (MRS) study on hippocampus has been performed in obsessive-compulsive disorder (OCD). The purpose of the present study was therefore to compare hippocampal chemicals in patients with OCD with those in healthy subjects with no psychopathology. METHODS: Eighteen patients meeting ...
Zanarini Mary C - - 2009
This study assessed the defensive functioning of 290 criteria-defined borderline patients and compared it to that of 72 patients with other forms of axis II psychopathology. The Defense Style Questionnaire (DSQ), a self-report measure with demonstrated criterion validity and internal consistency, was administered to 362 axis II inpatients diagnosed using ...
Borroni Barbara - - 2009
BACKGROUND: A careful characterization of behavioral abnormalities in corticobasal degeneration syndrome (CBDS) and progressive supranuclear palsy (PSP) by reliable tools is still lacking. Literature data provided evidence of the usefulness of the Frontal Behavioral Inventory (FBI) to operationalize such disturbances, particularly in the frontotemporal lobar degeneration spectrum. The study aimed ...
de Kraker M - - 2009
STUDY DESIGN: Clinical measurement, cross sectional. PURPOSE: To introduce a new measurement device, the Pollexograph, to easily measure palmar thumb abduction, and to compare its reliability with conventional goniometry. METHODS: Fourteen hand therapists measured palmar abduction of the same healthy subject with the Pollexograph and a conventional goniometer. In addition, ...
Salmi Peter - - 2009
OBJECTIVE: The aim was to investigate the results of multidisciplinary investigations of long-term sickness absentees regarding diagnoses, degree and prognoses of work incapacity, and need of rehabilitation measures and whether this was associated with socio-demographic factors. METHOD: A cross-sectional study of 545 long-term (>1 year) sickness absentees referred to multidisciplinary ...
Handler Leonard - - 2009
In this article, I review the contributions of Paul Lerner concerning his "humanistic-clinical attitude" in using the Rorschach (Exner, 2003) with patients. To illustrate Paul's empathic attitude, I present a case in which the patient's percepts reflected his relationship problems and his experience of me and others as a threat ...
Haaland V Ø - - 2009
OBJECTIVE: Transient, stress-related severe dissociative symptoms or paranoid ideation is one of the criteria defining the borderline personality disorder (BPD). Examinations of the neuropsychological correlates of BPD reveal various findings. The purpose of this study was to investigate the association between dissociation and neuropsychological functioning in patients with BPD. METHOD: ...
Gooding Diane C - - 2008
This review focuses on saccade research with adult psychiatric patients. It begins with an introduction of the various types of saccades and the tasks used to evoke them. The functional significance of the different types of eye movements is briefly discussed. Research findings regarding the saccadic performance of different adult ...
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