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Schmeiser Tim - - 2012
Systemic sclerosis (SSc) is a connective tissue diseases characterised by excessive thickening of the dermis in addition to affection of internal organs. Many patients experience musculoskeletal symptoms, but arthritis is still considered to be a rare manifestation. Therefore, we analysed a cohort of SSc patients in our department and related ...
Van Gaalen Floris Alexander - - 2012
The human leukocyte antigen (HLA)-B*2706 is a relatively rare subtype of HLA-B27. In contrast to most HLA-B27 subtypes, some studies have reported HLA-B*2706 to be protective against ankylosing spondylitis (AS). A systematic review and a meta-analysis of available studies was performed to investigate the association of HLA-B*2706 with AS. After ...
Alves Celina - - 2011
To identify regions of interest (ROIs) relevant to periarticular osteoporosis in RA with low precision error and sufficient inter-rater reliability and to test diagnostic validity for RA. Periarticular BMD was measured using dual-energy X-ray absorptiometry (DXA). Five ROIs were defined around MCP and/or PIP joints II-V, II-IV and mid-metacarpal to ...
Feldman R J - - 2011
Background:  Information on certain immunological parameters in patients with pemphigus vulgaris (PV) treated with rituximab (RTX) and intravenous immunoglobulin (IVIG) therapy is limited. Objective:  Comparing immunological parameters in patients who achieved long-term clinical remission (LTR) to those who relapsed. Methods:  Retrospective analysis of 19 patients treated at a single center ...
Zeigelboim Bianca Simone - - 2011
To describe the alterations observed in electronystagmography (ENG) of patients with spinocerebellar ataxia (SCA) types 2 and 3. Sixteen patients were studied and the following procedures were carried out: anamnesis, otorhinolaryngological and vestibular evaluations. The clinical findings in the entire group of patients were: gait disturbances (93.75%), dysarthria (43.75%), headache ...
Tubby Carolyn - - 2011
Asthma is characterized by airflow obstruction that is usually completely reversible either spontaneously or in response to treatment. However, a small subset of patients with asthma display FAO (fixed airflow obstruction) despite optimal treatment, a feature more commonly associated with smoking-induced COPD (chronic obstructive pulmonary disease). Why some asthma patients ...
Al-Nakshabandi Nizar A - - 2011
The question arises about the chest X-ray findings and clinical symptoms in swine flu and about the most important clinical finding when correlated with the chest radiograph. Should physicians order a chest X-ray in each patient suspected of having swine flu? There were 179 patients with a high suspicion of ...
Mrabet Dalila - - 2011
Anti-cyclic citrullinated peptide antibodies (ACPA) seem to be produced locally at the site of joints inflammation in the first stage of rheumatoid arthritis (RA). A strong correlation between serum ACPA and ACPA in the synovial fluid (SF-ACPA) is now suggested. A case-control study was conducted to evaluate the usefulness of ...
Reiß Michael - - 2011
Statistics in the literature showed that neuro-otological diseases (i.e. sudden hearing loss or tinnitus) occur predominantly in the left ear. In a seven-study meta-analysis of patients suffering from vestibular neuritis, Reiß found no clear dominance of one side (50.8% on the right side, 48.4% on the left side and 0.8% ...
Hajalilou Mehrzad - - 2012
Background:  The familial clustering of rheumatoid arthritis (RA) in first and second degree relatives of patients supports the role of genetic factors. The proportion of heredity in its development is roughly 60%; however, most individuals closely related to someone with RA do not get the disease. Considering the lack of ...
Lee Young Bok - - 2011
Background  Twenty-nail dystrophy (TND) is an idiopathic and non-congenital nail dystrophy that is characterized by excess longitudinal ridges and loss of luster in multiple nail plates. There are a few studies on TND. Materials and methods  In order to investigate the demographic and clinical characteristics of patients with TND in ...
de Hair M J H - - 2011
OBJECTIVE.: We examined the implication of the use of the new classification criteria for rheumatoid arthritis (RA) in clinical practice in a very early arthritis cohort. METHODS.: We included 301 disease-modifying antirheumatic drug naïve early arthritis patients. Baseline diagnosis was assessed applying 1987 ACR and 2010 ACR/EULAR criteria for RA ...
Pliakou Xanthi I - - 2011
Rheumatoid arthritis (RA) in patients suffering from hemoglobinopathies is an important clinical problem, but the correlation between these diseases is still imperfectly known. The aim of this study was to analyze the clinical, serological and radiological characteristics of RA occurring in patients with hemoglobinopathies (thalassemia major, thalassemia intermedia and sickle-cell ...
Ouédraogo Dieu-Donné - - 2011
The objective of this work was to study the clinical and serological profiles of rheumatoid arthritis in Burkina Faso (West Africa). It is a cross-sectional study conducted from March 2006 to February 2009 in the Internal Medicine Department of the University Hospital Yalgado Ouedraogo. All patients seen in the rheumatologic ...
Krause D - - 2011
Glucocorticoids (GCs) have been an invaluable tool in the treatment of patients with rheumatoid arthritis (RA) for decades, with a focus mainly on symptom management. In addition, several studies in the last 15 years have shown that GCs are also disease-modifying in patients with RA - which implies that they ...
Lopez-Ben Robert R - - 2011
The purpose of this video article is to show the sonographic techniques and findings in evaluating the joints of the hands in patients with possible inflammatory arthritis and to review the sonographic appearance and grading of synovitis. This video article shows the value of a targeted approach for musculoskeletal ultrasound ...
Gent Yoony Y J - - 2011
OBJECTIVE: A prospective pilot study to determine whether macrophage targeting by (R)-[(11) C]PK11195 PET can visualise subclinical synovitis in arthralgia patients with positive anti-citrullinated protein antibodies (ACPA). METHODS: Twenty-nine arthralgia patients with positive ACPA, but without clinical arthritis, were included. High (spatial) resolution (R)-[(11) C]PK11195 PET scans of hands/wrists were ...
Cauberg E C C - - 2011
Abstract Purpose: To define in which patients who present with microscopic or macroscopic hematuria CT urography (CTU) is indicated as an imaging mode for the upper urinary tract (UUT). Patients and Methods: We conducted a prospective study on consecutive patients who attended a modern protocol-driven hematuria clinic from January 2006 ...
Papadopoulou-Legbelou Kyriaki - - 2011
OBJECTIVE: To investigate cardiac complications in infectious mononucleosis patients and to associate them with biochemical and immunological parameters, as well as with spleen ultrasound findings. DESIGN: Cross-sectional study with follow-up. SETTING: Tertiary care pediatric unit, in the city of Thessaloniki, Greece. PARTICIPANTS AND INTERVENTIONS: Twenty-five children (15 boys, aged 1-11.6 ...
Iwasaki Shinichi - - 2011
To evaluate vestibular function in patients with the mitochondrial A3243G mutation. Data from patients with the A3243G mutation attending an academic tertiary referral center were prospectively recorded. The clinical histories of 13 unrelated patients with the mitochondrial A3243G mutation (six mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes; and seven maternally ...
Sahatçiu-Meka Vjollca - - 2011
Long since it have been suggested that a subpopulation of patients with rheumatoid arthritis, diagnosed with negative rheumatoid factor tests, represents a clinical entity quite distinct from that of seropositive rheumatoid arthritis (RA). Our aim was to establish a scientific comparative analysis between seronegative and seropositive rheumatoid arthritis, regarding some ...
Szilágyi G - - 2011
Szilágyi G, Vas Á, Kerényi L, Nagy Z, Csiba L, Gulyás B. Correlation between crossed cerebellar diaschisis and clinical neurological scales. Acta Neurol Scand: DOI: 10.1111/j.1600-0404.2011.01576.x. © 2011 John Wiley & Sons A/S. Background -  A common consequence of unilateral stroke is crossed cerebellar diaschisis (CCD), a decrease in regional blood ...
Zhang Yu Y Center for Imaging of Neurodegenerative Diseases, Veterans Affairs Medical Center, San Francisco, CA, USA. - - 2011
Whether longitudinal diffusion tensor MRI imaging (DTI) can capture disease progression in patients with amyotrophic lateral sclerosis (ALS) is unclear. The primary goal of this study was to determine if DTI detects progression of the corticospinal tracts (CST) degeneration in ALS. Seventeen ALS patients and 19 age- and gender-matched healthy ...
Eberst-Ledoux Julie - - 2011
BACKGROUND: No microorganism is identified in 7-35% of cases of septic arthritis. The diagnosis is, therefore, only presumptive. We reviewed our cases of septic arthritis in adult native joints to determine the frequency of negative cultures, disease characteristics and the frequency of misdiagnosis of septic arthritis. METHODS: This retrospective study ...
Skare Thelma Larocca - - 2011
Extra-articular manifestations are found in up to 50% of the patients with rheumatoid arthritis (RA). To assess the prevalence of pulmonary changes on high-resolution computed tomography (HRCT) in patients with RA and their association with demographic, clinical, serological and therapeutic variables. Seventy-one patients with RA were assessed regarding their age ...
Kwon H H - - 2011
Background.  Hyperuricaemia is a common finding in patients with psoriasis. However, previous studies have reported inconsistent results about the association between serum uric acid concentration (SUAC) and psoriasis severity. Recent studies have also reported that SUAC is associated with metabolic dysregulation. Aim.  To assess any association between SUAC and clinical ...
Santino I - - 2011
Serology is currently the method of choice for the laboratory diagnosis of Lyme Borreliosis, but it must be interpreted with caution. A total of 954 patients with suspected Lyme borreliosis were evaluated on the basis of clinical and serological data. The seroprevalence of Borrelia burgdorferi antibodies was 4.4 percent (42 ...
Biswas Monodeep - - 2011
Rheumatoid arthritis is a multi-system autoimmune disorder predominantly involving multiple small and large joints along with certain extra-articular manifestations. The presence of peripheral neuropathy in patients with rheumatoid arthritis contributes significantly to the functional limitation in patients with rheumatoid arthritis. To study the prevalence, types, and determinants of peripheral neuropathy ...
Cucnik S - - 2011
Objective. The objective of this study was to extend the findings of the preliminary study by measuring the avidity of IgG anti-β2-glycoprotein I antibodies (anti-β2-GPI) on a larger group of patients with primary or secondary antiphospholipid syndrome (APS) and anti-β2-GPI positive patients without APS in the frame of the European ...
Hewett Russell - - 2011
We describe a series of adolescents and adults who share the electroclinical characteristics of a nonlesional, pharmacoresponsive epilepsy manifesting as prominent vestibular disturbances, suggesting a temporo-parieto-occipital (TPO) junction origin. We retrospectively reviewed a database of consecutive patients referred to the epilepsy clinic over a 10-year period with respect to the ...
Howng Shen-Long - - 2011
Centrosomes are organelles involved in the organization of the mitotic spindle and may also be the targets of autoantibodies in autoimmune diseases. Human Ninein (hNinein) is a centrosomal autoantigen that is identified by autoimmune patient sera. However, none of the hNinein-specific fragments recognized by the autoantibodies in rheumatoid arthritis (RA) ...
Monaco A - - 2011
The purpose of this study was to investigate the prevalence of astigmatism among a paediatric population. A total of 322 consecutive patients of the department of Orthodontics and Gnathology, Dental Clinic, University of L'Aquila, were enlisted for the study and 176 were selected according to the exclusion criteria. Pre- treatment ...
Lee Min Hee - - 2011
The purpose of this article is to evaluate prospectively the utility of sonographic measurements of the common extensor tendon for diagnosing lateral epicondylitis. Forty-eight patients with documented lateral epicondylitis and 63 healthy volunteers were enrolled and underwent ultrasound of the elbow joint. The common extensor tendon overlying the bony landmark ...
Glasnović Marija - - 2011
The aim of this study was to present our experiences in diagnosing spondyloarthritides (SpA), and to list the most common clinical features of HLA-B27 positive patients. The study included 65 HLA-B27 positive patients with confirmed diagnosis of ankylosing spondylitis (AS) and psoriatic arthritis (PsA) who were analyzed between 2009 and ...
Felgentreff Kerstin - - 2011
Hypomorphic mutations in genes associated with severe combined immunodeficiency (SCID) or Omenn syndrome can also cause milder immunodeficiencies. We report 10 new patients with such "atypical" SCID and summarize 63 patients from the literature. The patient groups with T(low)B(low) (n=28), T(low)B(+) (n=16) and ADA (n=29) SCID variants had similar infection ...
Alves Celina - - 2011
An ACR/EULAR task force released new criteria to classify rheumatoid arthritis at an early stage. This study evaluates the diagnostic performance of these criteria and algorithms by van der Helm and Visser in REACH. Patients with symptoms ≤12 months from REACH were used. Algorithms were tested on discrimination, calibration and ...
Zielonka Tadeusz M - - 2011
The role of angiogenesis in the pathogenesis of tuberculosis (TB) is not clear. The aim of this study was to examine the effect of sera from TB patients on angiogenesis induced by different subsets of normal human mononuclear cells (MNC) in relation to IL-12p40 and TNFα serum levels. Serum samples ...
Stephenson Sean R - - 2011
Rheumatoid arthritis (RA) is a chronic inflammatory arthritis that can present with many unique cutaneous manifestations including palisaded neutrophilic and granulomatous dermatitis (PNGD). The authors present a case of PNGD in a RA patient on adalimumab therapy. The potential association of PNGD and adalimumab therapy is discussed as well as ...
Esmaeili Heidarali - - 2011
Recently, it is hypothesized that there might be an association between immunological disorders and cervical premalignant and malignant abnormalities. Related studies have been generally focused on some particular autoimmune disease, specially the Systemic Lupus Erythematosus (SLE). This study aimed at comparing the rate of Pap smear abnormalities in female patients ...
Derebery M Jennifer - - 2011
Ménière's disease (MD), which by definition is idiopathic, has been ascribed to various causes, including both inhalant and food allergies. Patients with MD report higher rates of allergy history and positive skin or in vitro tests compared with a control group of patients with other otologic diseases and to the ...
Samara Osama A - - 2011
The aim of this study was to find an accurate, easily available and safe imaging modality as an alternative to intravenous urography for the diagnosis of acute urinary obstruction. This retrospective study included 332 patients, who underwent both excretory urography (EU) preceeded by plain radiograph as well as ultrasonography for ...
Baroni Adone - - 2011
A 25-year-old man presented with Touraine-Solente-Golé syndrome (primary pachydermoperiostosis), with an area of inflammatory dermatosis (12-month evolution) of the scalp at the cranial vertex. The patient presented with arthropathy, clubbing of the digits, diffuse periostosis, pachydermia of the hands and feet, and periosteal hyperostosis of the knee. Facial seborrhea and ...
Hanaoka Takuya - - 2011
Background and Aim:  The purpose of the present study was to investigate the clinical significance of the highly sensitive fucosylated fraction of α-fetoprotein (hs-AFP-L3) in patients with chronic liver disease (CLD) and low serum α-fetoprotein (AFP) concentration. Methods:  A total of 241 patients being treated at our institute with CLD ...
Held J - - 2011
Clin Microbiol Infect 2011; 17: 595-602 ABSTRACT: Pneumocystis jirovecii (carinii) pneumonia (PJP) is a major cause of disease in immunocompromised individuals. However, until recently no reliable and specific serological parameters for the diagnosis of PJP have been available. (1→3)-β-d-Glucan (BG) is a cell wall component of P. jirovecii and of various ...
Aslan Mustafa - - 2011
Cystic echinococcosis (CE) is the larval cystic stage (called echinococcal cysts) of a small taeniid-type tapeworm (Echinococcus granulosus). Carnivores such as dogs are usually definitive hosts. Intermediate hosts are typically herbivores such as sheep and cattle. CE can be detected using various imaging techniques such as ultrasonography or radiology. Moreover ...
Foocharoen Chingching - - 2011
Background:  Undifferentiated arthritis (UA) comprises arthritis not yet identifiable as a specific rheumatic disease. Few reports exist on the natural course of UA in Thai patients. Objective:  To study the clinical features and natural course of UA in Thai patients. Method:  A retrospective, analytical study was performed among Thai patients ...
Alves Jorge Augusto Nunes Rodrigues - - 2011
Some studies have reported that adding leflunomide (LEF) to the treatment of rheumatoid arthritis (RA) in patients who do not respond to methotrexate (MTX) improved efficacy but increased the risk of liver toxicity. This study aimed at assessing the incidence of liver toxicity in patients with active RA using the ...
Fernández de Larrea Carlos - - 2011
In recent years, better diagnostics for tuberculosis (TB) has received increasing attention, especially the diagnosis of tuberculous pleural effusion, which is difficult and at present the main tool in TPE diagnostic is pleural effusion smear and culture, but unfortunately, sensitivities are low, therefore better TPE diagnostic tools are needed. The ...
Foocharoen Chingching - - 2011
There are reports of a correlation between high adenosine deaminase (ADA) levels in body fluid and tuberculosis (TB) infection, but none have evaluated synovial fluid ADA and TB arthritis. The objectives of this study were to determine the proper cut-off level for synovial fluid adenosine deaminase (SF-ADA) and the sensitivity ...
Hiwarkar P - - 2011
Hiwarkar P, Shaw BE, Tredger JM, Brown NW, Kulkarni S, Saso R, Evans S, Treleaven J, Davies FE, Ethell ME, Morgan GJ, Potter MN. Mycophenolic acid trough level monitoring: relevance in acute and chronic graft versus host disease and its relation with albumin. Clin Transplant 2011: 25: 222-227. © 2010 ...
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