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Zakeri Zahra - - 2012
Adenosine deaminase (ADA) is an enzyme being involved in purine metabolism and plays a significant role in the immune system. The aim of this study was to investigate the use of adenosine deaminase levels in differentiating between rheumatoid arthritis and osteoarthritis. Thirty patients with rheumatoid arthritis and 30 osteoarthritis patients ...
Ercan Altan - - 2012
Rheumatoid arthritis (RA) is associated with hypogalactosylation of immunoglobulin G (IgG). We examined whether a proxy measure for galactosylation of IgG N-glycans could predict response to therapy or was differentially affected by methotrexate (MTX) or TNF blockade. Using a previously defined normal phase high-performance liquid chromatography approach, we ascertained the ...
Sahin Ziver - - 2012
HLA-B*51 and HLA-B*52 are two close human leukocyte antigen (HLA) allele groups with minor amino acid differences. However, they are associated with two different vasculitides (HLA-B*51 in Behçet's disease and HLA-B*52 in Takayasu's arteritis (TAK)) and with major clinical and immunological differences. In this study, we aimed to screen a ...
Monzon Jose G - - 2012
Interferon is the only accepted adjuvant treatment for patients with melanoma; hence, oncologists should be aware of the possibility of retinal abnormalities resulting from its use. Interferon-associated retinopathy in patients being treated for resected melanoma is a rare phenomenon with a proposed immunological basis. Patients are usually asymptomatic or have ...
Mohammadinejad P - - 2012
Common variable immunodeficiency (CVID) is the most common form of symptomatic primary immunodeficiency disease. It is characterized by hypogammaglobulinemia, increased predisposition to infections, autoimmunity, and cancer. This study was performed to evaluate the clinical and immunological features of a group of pediatric patients with CVID. The study population comprised 69 ...
Lanteri Alexis Caitlin AC Operation Smile, Inc, Norfolk, - - 2012
The purpose of this cross-sectional study was to compare the severity of unilateral cleft lips in populations of Asia, Sub-Saharan Africa, and Northern Africa and the Middle East. We hypothesize that severity of unilateral cleft lips shows significant variation between these populations. Medical photographs of 780 patients with primary unilateral ...
Krempaska S S University of P.J. Safarik, Slovakia. - - 2012
This study presents the role of vestibular evoked myogenic potentials (VEMPs) in the vestibular system investigation focused on the function of the saccule and inferior portion of the vestibular nerve. The main goal of the study is to report VEMP findings in different groups of patients with inner ear disorders ...
Lim Hyun Woo - - 2011
OBJECTIVE: Despite complaints of dizziness, some patients with unilateral compensated vestibular weakness show normal results on Sensory Organization Test (SOT), which is being widely used for the evaluation of vestibular function compensation. The head shake-sensory organization test (HS-SOT) has been suggested to increase the sensitivity of SOT. In HS-SOT, the ...
Marmor Michael F - - 2011
OBJECTIVES: To compare different screening procedures for hydroxychloroquine sulfate (Plaquenil) toxicity at different stages of damage. METHODS: Ten patients were studied using 10-2 automated fields, multifocal electroretinography, spectral domain optical coherence tomography (SD-OCT), and fundus autofluorescence. RESULTS: All 10 patients used hydroxychloroquine for more than 6 years, and those with ...
Kikuchi Tsutomu - - 2011
This study aimed to estimate the prevalence of sexual dysfunction, evaluated by the Nagoya Sexual Function Questionnaire (NSFQ), and hyperprolactinemia in patients with schizophrenia and examine a relationship between sexual dysfunction and serum prolactin levels. This cross-sectional, comparative study was performed using a sample comprising 195 Japanese schizophrenic in- and ...
Abbasi Amanullah - - 2011
Objective: To determine the frequency of portal hypertensive gastropathy (PHG) and its relation with biochemical, haematological and endoscopic findings in cirrhotic patients. Study Design: Cross-sectional analytical study. Place and Duration of Study: Jinnah Postgraduate Medical Centre, Karachi, Medical Unit-III, Ward-7, from June 2009 to December 2010. Methodology: Patients with diagnosis ...
Magalhães Belisa Maria Lopes - - 2011
Deforestation, uncontrolled forest, human population migration from endemic areas, and the large number of reservoirs and wild vectors naturally infected by Trypanosoma cruzi promote the endemicity of Chagas disease in the Amazon region. We conducted an initial serological survey (ELISA) in a sample of 1,263 persons; 1,095 (86.7%) were natives ...
Goyal Nishant - - 2011
The objective of our study was to examine the electroencephalogram (EEG) abnormalities associated with clozapine treatment. It was a cross-sectional study on 87 psychiatric patients on clozapine treatment. 32 channel digital EEG was recorded and analysed visually for abnormalities. EEG abnormalities were observed in 63.2% of patients. Both slowing and ...
Oliveira Ana Cecília Diniz - - 2011
BACKGROUND: Behçet disease (BD) is prevalent in Central and East Asia and in the Eastern Mediterranean area where most studies have been performed. Few studies have evaluated patients with BD in Brazil. OBJECTIVES: The objective of the study was to describe clinical manifestations of BD and their therapy in a ...
Tillett William - - 2011
OBJECTIVE: To evaluate the sensitivity, specificity, and feasibility of the ClASsification criteria for Psoriatic ARthritis (CASPAR) to retrospectively classify an existing research cohort. METHODS: In total, 480 patient records were reviewed from the Royal National Hospital for Rheumatic Diseases Psoriatic Arthritis (PsA) cohort and for 100 consecutive controls with inflammatory ...
Mrabet Dalila - - 2011
Autoantibodies to citrullinated proteins (ACPA) are specifically associated with rheumatoid arthritis (RA) and seem to play an important role in its pathogenesis. The specific immunological conflict between ACPA and citrullinated fibrin plays a major role in the self-maintenance of synovial inflammation by forming fibrin deposits in the synovial tissue. These ...
Kyriakou Aikaterini - - 2011
Background:Occurrence rates of specific features of psoriatic nails, as well as the influence of variable clinical parameters on nail involvement in psoriasis, are not determined. Objective:To evaluate the frequency and characteristics of nail involvement in patients with psoriasis and determine the relationship between nail psoriasis and clinical parameters (age, gender, ...
Hattori T - - 2011
BACKGROUND AND PURPOSE:The fornix contains efferent fibers of the hippocampus and is in close contact with the corpus callosum. Part of the fornix is directly attached to the corpus callosum, and another part is suspended from the corpus callosum via the septum pellucidum. DTI can be used to evaluate the ...
Kopac P - - 2011
To cite this article: Kopac P, Rudin M, Gentinetta T, Gerber R, Pichler C, Hausmann O, Schnyder B, Pichler WJ. Continuous apple consumption induces oral tolerance in birch-pollen-associated apple allergy. Allergy 2011; DOI: 10.1111/j.1398-9995.2011.02744.x. ABSTRACT: Background:  Patients with birch pollen allergy (major allergen: Bet v 1) have often an associated ...
Tsutsumi Takeshi - - 2011
OBJECTIVE:: Three-dimensional analysis of video-oculograms can be used to calculate Listing plane for patients and experimental subjects. Listing plane reflects the head's orientation with respect to gravity, which suggests that the plane is derived from otolithic vestibular input, itself, or from a gravity-oriented internal model constructed through integration of visual, ...
Kaarela Kalevi - - 2011
The aim of this study was to evaluate the 2010 American College of Rheumatology/European League Against Rheumatism (ACR/EULAR) classification criteria for rheumatoid arthritis (RA) in a cohort with early arthritis and true diagnosis confirmed by long-term follow-up. The criteria were tested in the Heinola community-based inception cohort of 121 true ...
Filippucci Emilio - - 2011
OBJECTIVE: To assess the prevalence and the distribution of tendon involvement in the hands and wrists of patients with rheumatoid arthritis (RA) describing in detail the ultrasound (US) morphostructural and vascular tendon abnormalities. METHODS: Ninety consecutive RA patients were included in the study. The following tendons were scanned bilaterally: flexor ...
Atmaca Murad - - 2011
There has been no study in the literature evaluating total blood count in obsessive-compulsive disorder (OCD). Therefore, we performed the present study to spesifically measure serum total blood count particularly white blood cells to see whether or not its eventual alterations might have an etiopathogenetic significance in patients with OCD. ...
Di Martino Maria Teresa - - 2011
Recent findings have disclosed the role of UDP-glucuronosyltransferase (UGT) 1A1*28 on the haematological toxicity induced by irinotecan (CPT-11), a drug commonly used in the treatment of metastatic colorectal cancer (mCRC). We investigated the pharmacogenomic profile of irinotecan-induced gastrointestinal (GI) toxicity by the novel drug-metabolizing enzyme and transporter (DMET) microarray genotyping ...
Emmrich Julius V - - 2011
Large vestibular aqueduct syndrome (LVAS) is one of the most common anomalies of the inner ear. The purpose of our study was to evaluate the vestibule for associated aberrations. In particular, we assessed the vestibular volume in patients with LVAS, compared it to an age-matched control population, and evaluated the ...
Fautrel B - - 2011
BACKGROUND: In 2010, new classification criteria for rheumatoid arthritis (RA) were developed.OBJECTIVE: To assess agreement between 1987 American College of Rheumatology (ACR) and 2010 ACR/European League Against Rheumatism (EULAR) criteria and the potential source of discordance, based on ESPOIR cohort data.METHODS: 813 early arthritis patients were included in ESPOIR between ...
Agarwal Ritesh - - 2011
Currently, there is not a uniform consensus regarding the number of criteria or specific cut-off values for the variety of tests that are used to diagnose allergic bronchopulmonary aspergillosis (ABPA). Traditionally, an eosinophil count >1000cells/μl is considered an important criterion in the diagnosis of ABPA. The goal of this study ...
Schmeiser Tim - - 2012
Systemic sclerosis (SSc) is a connective tissue diseases characterised by excessive thickening of the dermis in addition to affection of internal organs. Many patients experience musculoskeletal symptoms, but arthritis is still considered to be a rare manifestation. Therefore, we analysed a cohort of SSc patients in our department and related ...
Van Gaalen Floris Alexander - - 2012
The human leukocyte antigen (HLA)-B*2706 is a relatively rare subtype of HLA-B27. In contrast to most HLA-B27 subtypes, some studies have reported HLA-B*2706 to be protective against ankylosing spondylitis (AS). A systematic review and a meta-analysis of available studies was performed to investigate the association of HLA-B*2706 with AS. After ...
Alves Celina - - 2011
To identify regions of interest (ROIs) relevant to periarticular osteoporosis in RA with low precision error and sufficient inter-rater reliability and to test diagnostic validity for RA. Periarticular BMD was measured using dual-energy X-ray absorptiometry (DXA). Five ROIs were defined around MCP and/or PIP joints II-V, II-IV and mid-metacarpal to ...
Feldman R J - - 2011
Background:  Information on certain immunological parameters in patients with pemphigus vulgaris (PV) treated with rituximab (RTX) and intravenous immunoglobulin (IVIG) therapy is limited. Objective:  Comparing immunological parameters in patients who achieved long-term clinical remission (LTR) to those who relapsed. Methods:  Retrospective analysis of 19 patients treated at a single center ...
Zeigelboim Bianca Simone - - 2011
To describe the alterations observed in electronystagmography (ENG) of patients with spinocerebellar ataxia (SCA) types 2 and 3. Sixteen patients were studied and the following procedures were carried out: anamnesis, otorhinolaryngological and vestibular evaluations. The clinical findings in the entire group of patients were: gait disturbances (93.75%), dysarthria (43.75%), headache ...
Tubby Carolyn - - 2011
Asthma is characterized by airflow obstruction that is usually completely reversible either spontaneously or in response to treatment. However, a small subset of patients with asthma display FAO (fixed airflow obstruction) despite optimal treatment, a feature more commonly associated with smoking-induced COPD (chronic obstructive pulmonary disease). Why some asthma patients ...
Al-Nakshabandi Nizar A - - 2011
The question arises about the chest X-ray findings and clinical symptoms in swine flu and about the most important clinical finding when correlated with the chest radiograph. Should physicians order a chest X-ray in each patient suspected of having swine flu? There were 179 patients with a high suspicion of ...
Mrabet Dalila - - 2011
Anti-cyclic citrullinated peptide antibodies (ACPA) seem to be produced locally at the site of joints inflammation in the first stage of rheumatoid arthritis (RA). A strong correlation between serum ACPA and ACPA in the synovial fluid (SF-ACPA) is now suggested. A case-control study was conducted to evaluate the usefulness of ...
Reiß Michael - - 2011
Statistics in the literature showed that neuro-otological diseases (i.e. sudden hearing loss or tinnitus) occur predominantly in the left ear. In a seven-study meta-analysis of patients suffering from vestibular neuritis, Reiß found no clear dominance of one side (50.8% on the right side, 48.4% on the left side and 0.8% ...
Hajalilou Mehrzad - - 2012
Background:  The familial clustering of rheumatoid arthritis (RA) in first and second degree relatives of patients supports the role of genetic factors. The proportion of heredity in its development is roughly 60%; however, most individuals closely related to someone with RA do not get the disease. Considering the lack of ...
Lee Young Bok - - 2011
Background  Twenty-nail dystrophy (TND) is an idiopathic and non-congenital nail dystrophy that is characterized by excess longitudinal ridges and loss of luster in multiple nail plates. There are a few studies on TND. Materials and methods  In order to investigate the demographic and clinical characteristics of patients with TND in ...
de Hair M J H - - 2011
OBJECTIVE.: We examined the implication of the use of the new classification criteria for rheumatoid arthritis (RA) in clinical practice in a very early arthritis cohort. METHODS.: We included 301 disease-modifying antirheumatic drug naïve early arthritis patients. Baseline diagnosis was assessed applying 1987 ACR and 2010 ACR/EULAR criteria for RA ...
Pliakou Xanthi I - - 2011
Rheumatoid arthritis (RA) in patients suffering from hemoglobinopathies is an important clinical problem, but the correlation between these diseases is still imperfectly known. The aim of this study was to analyze the clinical, serological and radiological characteristics of RA occurring in patients with hemoglobinopathies (thalassemia major, thalassemia intermedia and sickle-cell ...
Ouédraogo Dieu-Donné - - 2011
The objective of this work was to study the clinical and serological profiles of rheumatoid arthritis in Burkina Faso (West Africa). It is a cross-sectional study conducted from March 2006 to February 2009 in the Internal Medicine Department of the University Hospital Yalgado Ouedraogo. All patients seen in the rheumatologic ...
Krause D - - 2011
Glucocorticoids (GCs) have been an invaluable tool in the treatment of patients with rheumatoid arthritis (RA) for decades, with a focus mainly on symptom management. In addition, several studies in the last 15 years have shown that GCs are also disease-modifying in patients with RA - which implies that they ...
Lopez-Ben Robert R - - 2011
The purpose of this video article is to show the sonographic techniques and findings in evaluating the joints of the hands in patients with possible inflammatory arthritis and to review the sonographic appearance and grading of synovitis. This video article shows the value of a targeted approach for musculoskeletal ultrasound ...
Gent Yoony Y J - - 2011
OBJECTIVE: A prospective pilot study to determine whether macrophage targeting by (R)-[(11) C]PK11195 PET can visualise subclinical synovitis in arthralgia patients with positive anti-citrullinated protein antibodies (ACPA). METHODS: Twenty-nine arthralgia patients with positive ACPA, but without clinical arthritis, were included. High (spatial) resolution (R)-[(11) C]PK11195 PET scans of hands/wrists were ...
Cauberg E C C - - 2011
Abstract Purpose: To define in which patients who present with microscopic or macroscopic hematuria CT urography (CTU) is indicated as an imaging mode for the upper urinary tract (UUT). Patients and Methods: We conducted a prospective study on consecutive patients who attended a modern protocol-driven hematuria clinic from January 2006 ...
Papadopoulou-Legbelou Kyriaki - - 2011
OBJECTIVE: To investigate cardiac complications in infectious mononucleosis patients and to associate them with biochemical and immunological parameters, as well as with spleen ultrasound findings. DESIGN: Cross-sectional study with follow-up. SETTING: Tertiary care pediatric unit, in the city of Thessaloniki, Greece. PARTICIPANTS AND INTERVENTIONS: Twenty-five children (15 boys, aged 1-11.6 ...
Iwasaki Shinichi - - 2011
To evaluate vestibular function in patients with the mitochondrial A3243G mutation. Data from patients with the A3243G mutation attending an academic tertiary referral center were prospectively recorded. The clinical histories of 13 unrelated patients with the mitochondrial A3243G mutation (six mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes; and seven maternally ...
Sahatçiu-Meka Vjollca - - 2011
Long since it have been suggested that a subpopulation of patients with rheumatoid arthritis, diagnosed with negative rheumatoid factor tests, represents a clinical entity quite distinct from that of seropositive rheumatoid arthritis (RA). Our aim was to establish a scientific comparative analysis between seronegative and seropositive rheumatoid arthritis, regarding some ...
Szilágyi G - - 2011
Szilágyi G, Vas Á, Kerényi L, Nagy Z, Csiba L, Gulyás B. Correlation between crossed cerebellar diaschisis and clinical neurological scales. Acta Neurol Scand: DOI: 10.1111/j.1600-0404.2011.01576.x. © 2011 John Wiley & Sons A/S. Background -  A common consequence of unilateral stroke is crossed cerebellar diaschisis (CCD), a decrease in regional blood ...
Zhang Yu Y Center for Imaging of Neurodegenerative Diseases, Veterans Affairs Medical Center, San Francisco, CA, USA. - - 2011
Whether longitudinal diffusion tensor MRI imaging (DTI) can capture disease progression in patients with amyotrophic lateral sclerosis (ALS) is unclear. The primary goal of this study was to determine if DTI detects progression of the corticospinal tracts (CST) degeneration in ALS. Seventeen ALS patients and 19 age- and gender-matched healthy ...
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