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Ho Chi-Wai CW From the Cardiology Division (C.-W.H., M.-H.H., P.-H.C., J.-J.H., E.C., C.-P.L., H.-F.T., C.-W.S.), Endocrinology Division (C.-Y.Y.), and Neurology Division (K.-K.L., K.-H.C.), Department of Medicine, Queen Mary Hospital and Division of Neurosurgery, Department of Surgery, Li Ka Shing Faculty of Medicine (G.K.-K.L.), University of Hong Kong, Hong Kong SAR, China; and University of Birmingham Centre for Cardiovascular Sciences, City Hospital, University Department of Medicine, Birmingham, United Kingdom - - 2014
Little is known about the impact of quality of anticoagulation control, as reflected by time in therapeutic range (TTR), on the effectiveness and safety of warfarin therapy in Chinese patients with atrial fibrillation. We investigated the risks of ischemic stroke and intracranial hemorrhage (ICH) in relation to warfarin at various ...
Yamauchi Hiroshi H From the Division of PET Imaging, Shiga Medical Centre Research Institute, Shiga, Japan. - - 2014
The benefit of strict blood pressure (BP) control in high-risk patients with symptomatic major cerebral artery disease and misery perfusion (MP) is controversial. Our purposes were (1) to determine whether MP is a predictor of a 5-year risk of subsequent stroke and (2) to investigate the relationships among BP during ...
Kongbunkiat Kannikar K 1Department of Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen, - - 2014
Abstract Purpose: To study factors associated with poor outcomes in acute ischemic stroke patients with AF by using a national database. Materials and Methods: This study was a retrospective analytical study by retrieving data from the Thailand national database system for universal coverage health insurance system. All adult patients aged ...
Ha Andrew C T AC aPeterMunk Cardiac Center, University Health Network, Toronto, Canada bDepartment of Electrophysiology, Heart Center, University of Leipzig, Leipzig, Germany cUniversity of Ottawa Heart Institute, Ottawa dSouthlake Regional Health Centre, Newmarket, Ontario, - - 2014
Catheter ablation for atrial fibrillation is an effective rhythm-control therapy for selected patients. Currently, it is unknown whether maintenance of sinus rhythm after atrial fibrillation ablation can reduce one's stroke risk. If so, this may potentially obviate the need to treat patients with long-term oral anticoagulation (OAC). This article reviews ...
Ntaios George G From the Department of Medicine, Larissa University Hospital, School of Medicine, University of Thessaly, Larissa, Greece (G.N., V.P., K.M.); Department of Medicine, Ioannina University Hospital, School of Medicine, University of Ioannina, Ioannina, Greece (H.M.); Department of Clinical Therapeutics, Medical School of Athens, Alexandra Hospital, Athens, Greece (E.M., K.V.); Department of Neurology, Eginition Hospital, University of Athens Medical School, Athens, Greece (K.S.); and Stroke Center, Neurology Service, CHUV, University of Lausanne, Lausanne, Switzerland (P.M.). - - 2014
A new clinical construct termed embolic stroke of undetermined source (ESUS) was recently introduced, but no such population has been described yet. Our aim is to provide a detailed descriptive analysis of an ESUS population derived from a large prospective ischemic stroke registry using the proposed diagnostic criteria. The criteria ...
Switońska M M Neurology and Stroke Care Unit, Jan Biziel University Hospital No. 2, Bydgoszcz, - - 2014
Stroke is an important cause of death and disability throughout the world. Microparticles play a cardinal role in vascular hemostasis. The primary aim of this study was to evaluate the procoagulant activity of microparticles and levels of tissue-factor-bearing microparticles (MPs-TF), tissue factor (TF) and tissue factor pathway inhibitor (TFPI) in ...
Strømmen Anna Maria AM From the Department of Neurology, Copenhagen University Hospital-Nordsjællands Hospital, Hillerød, Denmark. - - 2014
The purpose of this study was to quantitatively measure and describe the amount and pattern of physical activity in patients within the first week after acute ischemic stroke and transient ischemic attack using accelerometers. A total of 100 patients with acute ischemic stroke or transient ischemic attack admitted to our ...
Lee Jung Myung JM Division of Cardiology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, - - 2014
The association between pulmonary vein (PV) dilatation and stroke in non-valvular atrial fibrillation (AF) patients remains unknown. We examined the left atrium (LA) and PV in control (n=138) and non-valvular AF patients without (AF group, n=138) and with non-hemorrhagic stroke (AF with stroke group, n=138) using computed tomography. The LA, ...
Sluggett J K JK Quality Use of Medicines and Pharmacy Research Centre, Sansom Institute, School of Pharmacy and Medical Sciences, University of South Australia, Adelaide, South Australia, - - 2014
Hospital audits may underestimate anticoagulant use among acute ischaemic stroke patients with atrial fibrillation (AF), as treatment may commence after discharge. To account for this, antithrombotic use in the 4 months after hospitalisation for transient ischaemic attack or ischaemic stroke among AF patients was assessed using claims data. Results suggest ...
Tomazic Peter Valentin PV ENT, University Hospital (p.v.t., a.l., d.l-l.); the Institute of Pathology (r.b-g., b.d., s.s.); the Center of Medical Research, Mass Spectrometry Core Facility (s.s.), Medical University of Graz; The Austrian Center of Industrial Biotechnology (r.b-g., b.d., s.s.); and the The Omics Center Graz, BioTechMed (r.b-g., b.d., s.s.), Graz, - - 2014
Nasal mucus is a defense barrier against aeroallergens. We recently found apolipoproteins to be elevated in the nasal mucus of allergic rhinitis patients. Apolipoproteins are involved in lipid metabolism, have immunomodulatory properties, and may represent interesting novel biomarkers. This study aims to validate our findings and analyze whether the increased ...
Bembenek J P JP Second Department of Neurology, Institute of Psychiatry and Neurology, Warsaw, - - 2014
Effective anticoagulation with vitamin K antagonists (VKAs) is the standard of stroke prevention in patients with non-valvular atrial fibrillation (AF). Although, everyday practice is becoming increasingly guideline-driven, proper anticagulation is still problematic. We aimed to investigate changes in the use of VKAs for stroke prevention in patients with AF admitted ...
Man David D Department of Rehabilitation Sciences, Hong Kong Polytechnic University , Hong Kong , PR China - - 2014
Abstract Background and purpose: Prospective memory (PM) is a common problem which can limit performance of basic and instrumental activities of daily living in patients with stroke. This study compared self-report PM failures between older and younger people with stroke, examined differences in perceptions of PM failures between people with ...
Joux Julien J From the Departments of Neurology (J.J., N.C., S.J., M.S.-V., D.S., S.O.), Radiology (M.M.), Vascular Surgery (J.-L.H.), and Pathology (L.D.), Fort-de-France University Hospital, Martinique, French West Indies. - - 2014
An atypical form of fibromuscular dysplasia located in the internal carotid-bulb (CaFMD) is thought to be uncommon and is poorly described as a cause of ischemic stroke in the young. This study aimed to obtain a better description of CaFMD in Afro-Caribbean population, who could be particularly affected by it. ...
Lasek-Bal Anetta A Department of Neurology, Medical University of Silesia Hospital No. 7, Professor Leszek Giec Upper Silesian Medical Centre, Katowice, - - 2014
Background: An increase in the troponin I (TnI) level is a marker of myocardial damage in acute coronary syndromes (ACS) and other conditions. According to the latest reports, an increase in the concentration of TnI in the acute phase of stroke relates to 1-34% of patients. The aim of this ...
Choi Jay Chol JC Department of Neurology, Jeju National University, Jeju, - - 2014
Spontaneous echo-contrast (SEC) appears on B-mode images as moving curls of smoke in the lumen of veins. The aims of this study were to investigate the prevalence and characteristics of internal jugular vein SEC among patients with stroke, in comparison with control subjects. We enrolled 97 Korean patients with acute ...
Lantz M M Karolinska Institute, Department of Neurology, Karolinska University Hospital, Stockholm, - - 2014
Migraine, especially with aura, is a risk factor for ischemic stroke. In this study, we investigated descriptive data and prevalence of migraine in an in-patient stroke population. Patients with acute cerebrovascular disease (CVD) admitted to the stroke unit during a 6-month period were recruited. Prevalence of migraine was assessed using ...
Reid John M JM Department of Neurology, Aberdeen Royal Infirmary, Aberdeen, Scotland, - - 2014
Debate exists as to whether wake-up stroke (WUS) (i.e. symptoms first noted on waking) differs from stroke developing while awake [awake onset stroke (AOS)]. Unknown onset stroke (UOS) with unclear symptom onset time is infrequently studied. This study aimed to examine differences in stroke characteristics and outcomes in these three ...
Mantokoudis Georgios G *Department of Neurology, Johns Hopkins University School of Medicine; †Johns Hopkins Biostatistics Center; and ‡Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, U.S.A.; §University of Applied Sciences Upper Austria, Department of Medical Engineering, Linz, Austria; and ║University of Illinois College of Medicine, Peoria, Illinois, - - 2014
Vestibular neuritis is often mimicked by stroke (pseudoneuritis). Vestibular eye movements help discriminate the two conditions. We report vestibulo-ocular reflex (VOR) gain measures in neuritis and stroke presenting acute vestibular syndrome (AVS). Prospective cross-sectional study of AVS (acute continuous vertigo/dizziness lasting >24 h) at two academic centers. We measured horizontal ...
Lei Chunyan C Stroke Clinical Research Unit, Department of Neurology, West China Hospital, Sichuan University, Chengdu, P. R. - - 2014
Whether asymptomatic hemorrhagic transformation (HT) is clinically innocuous, that is, unassociated with clinically detectable neurologic deterioration, remains an open question. To explore this, we examined whether asymptomatic HT affects long-term poor outcome and risk of stroke recurrence. We consecutively and prospectively enrolled patients with acute ischemic stroke who were admitted ...
Yao Xiaoying X Department of Neurology, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, - - 2014
Background: Elevated maximal clot strength, measured by thrombelastography (TEG) maximum amplitude (MA) has been associated with a higher risk for ischemic events in patients with coronary artery diseases. However, it has not been investigated in patients with cerebrovascular diseases. In the current study, we aimed to evaluate the predictive ability ...
Saposnik Gustavo G From the Division of Neurology, Department of Medicine, Stroke Outcomes Research Center, St. Michael's Hospital, University of Toronto, Toronto, Ontario, Canada (G.S.); Division of Cardiology, University of California, Los Angeles (G.C.F.); Duke Clinical Research Institute, Durham, NC (W.P., L.L., A.F.H.); Stroke Service and Institute for Heart, Vascular and Stroke Care, Massachusetts General Hospital, Boston (L.H.S.); and Calgary Stroke Program, Hotchkiss Brain Institute, University of Calgary, Calgary, Alberta, Canada (E.E.S.). - - 2014
Limited information is available on stroke prevention in high-risk patients with preexisting cardiovascular disease. Our aim was to use admission low-density lipoprotein (LDL) values to evaluate differences in the attainment of National Cholesterol Education Program-Adult Treatment Panel III guidelines goals at the time of the index event in high-risk patients ...
Glotzer Taya V TV Hackensack University Medical Center, Hackensack, NJ. Electronic address: - - 2014
Stroke without an identifiable cause is frightening to patients and their families, and frustrating for the caring physician. Approximately 30 percent of patients with cardiac implanted electronic devices have some evidence of atrial fibrillation (AF), and much of it is silent; asymptomatic and previously unrecognized. This review will examine "silent ...
Werner Ralph R Department of Neurology/Stroke Unit, Katholisches Klinikum Koblenz-Montabaur, Koblenz, - - 2014
Background: Angioedema (AE) in stroke has been reported exclusively after thrombolysis with recombinant tissue-type plasminogen activator (rtPA). Previous studies proposed the insular cortex to play a specific role in the development of AE after stroke. We evaluated the incidence of AE in acute stroke and tried to identify the predominantly ...
Vanacker P P Neurology Service, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, - - 2014
Background: The effects of intravenous thrombolysis on floating thrombi in cervical and intracranial arteries of acute ischemic stroke patients are unknown. Similarly, the best prevention methods of early recurrences remain controversial. This study aimed to describe the clinical and radiological outcome of thrombolyzed strokes with floating thrombi. Methods: We retrospectively ...
Srivastava M V Padma MV Department of Neurology, AIIMS, New Delhi, India. Electronic address: - - 2014
Young stroke patients constitute 15%-30% of all stroke patients in India as against 3.0%-8.5% reported from the West. The mechanisms for stroke in the young may include unconventional risk factors such as infections. We aimed to investigate the role (if any) of Chlamydia pneumoniae antibodies in young patients with acute ...
Kim Ahro A Department of Neurology, Ilsan Paik Hospital, Inje University, 2240 Daewha-dong, Ilsanseo-gu, Goyang City, Gyeonggi-do 411-706, Republic of - - 2014
As the benefit of thrombolytic therapy in acute ischemic stroke is time-dependent, a code stroke program needs to be implemented, maintained, and improved with continuous efforts to expedite thrombolytic therapy. We analyzed the long-term yield and efficiency of our code stroke program. Using a prospective single-center registry, we assessed the ...
Yaghi Shadi S Department of Neurology, College of Physicians and Surgeons (SY, MSVE), and Department of Epidemiology, Mailman School of Public Health (MSVE), Columbia University, New York, - - 2014
Cryptogenic, or unexplained, stroke is present in about 30%-40% of ischemic stroke patients. Pursuing a stroke mechanism is important in such patients to better choose therapy to reduce the stroke recurrence risk. Intracranial vessel imaging and cardiac evaluation with transesophageal echocardiogram and outpatient cardiac monitoring may help identify the stroke ...
Zhang Changqing C Department of Neurology, Beijing Tian Tan Hospital, Capital Medical University, Beijing, China; China National Clinical Research Center for Neurological Diseases, Beijing, - - 2014
Leukoaraiosis (LA) is an indicator of small vessel disease, but little is known about the relationship between the severity of LA and etiologic subtype of ischemic stroke. Our study aimed to investigate the factors associated with the severity of LA and the relationship between the severity of LA and etiologic ...
Novotná Jana J International Clinical Research Center, Department of Neurology, St. Anne's Hospital, Brno, Czech Republic; Masaryk University, Brno, Czech Republic. Electronic address: - - 2014
The hyperdense cerebral artery sign (HCAS) on unenhanced computed tomography (CT) in acute ischemic stroke is a valuable clinical marker, but it remains unclear if HCAS reflects clot composition or stroke etiology. Therefore, variables independently associated with HCAS were identified from a large international data set of patients treated with ...
Schaefer P W PW From the Departments of Radiology (P.W.S., B.P., W.A.C., J.A.H., T.L.-M., O.W., R.G.G., A.J.Y.) and Neurology (L.H.S.), Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts. - - 2014
Selecting acute ischemic stroke patients for reperfusion therapy on the basis of a diffusion-perfusion mismatch has not been uniformly proved to predict a beneficial treatment response. In a prior study, we have shown that combining clinical with MR imaging thresholds can predict clinical outcome with high positive predictive value. In ...
Fjetland L L Department of Radiology, Stavanger University Hospital, Stavanger, Norway; Neuroscience Research Group, Stavanger University Hospital, Stavanger, - - 2014
The direct bridging concept in acute stroke treatment combines intravenous thrombolysis (IVT) and endovascular treatment (EVT). The frequency and extent of reperfusion obtained already due to IVT were evaluated. Additionally undesired events and the clinical outcome were analysed. Fifty-seven acute stroke patients treated with direct bridging were analysed for this ...
Cao Lei L Department of Rehabilitation, Xuanwu Hospital Capital Medical University, Changchun Street, Xicheng District No. 45, Beijing, 100053, People's Republic of - - 2014
Emerging evidence has shown that repetitive transcranial magnetic stimulation (rTMS) may significantly improve cognitive impairment in stroke patients, but individually published studies show inconclusive results. This meta-analysis aimed to derive a more precise estimation of the effects of rTMS on cognitive impairment in stroke patients based on studies published in ...
Cardoso Rhanderson N RN Department of Internal Medicine, University of Miami/Jackson Memorial Hospital, Miami, - - 2014
Chagas' disease (CD) has been associated with an elevated risk of stroke, but current data are conflicting and prospective controlled studies are lacking. We performed a systematic review and meta-analysis examining the association between stroke and CD. PubMed, EMBASE, Cochrane Central, Latin American databases and unpublished data were searched using ...
Nordin Nurdiana - - 2014
Studies of stroke patients undergoing robot-assisted rehabilitation have revealed various kinematic parameters describing movement quality of the upper limb. However, due to the different level of stroke impairment and different assessment criteria and interventions, the evaluation of the effectiveness of rehabilitation program is undermined.This paper presents a systematic review of ...
Toscano Massimiliano M Department of Neurology and Psychiatry, 'Sapienza' University of Rome, Rome, - - 2014
Anger and aggressive behavior (AB) are two of the main post-stroke behavioral manifestations, which could imply both an anger trait (TA) or a state condition of anger (SA). Serotonergic system is thought to play an inhibitory control on aggressive impulse. Nevertheless, whether 5HT has the same role in TA and ...
Khadanga Sherrie S Department of Medicine, University of Vermont, 111 Colchester Avenue, Fletcher 311, Burlington, VT, - - 2014
Vitamin D insufficiency is increasingly gaining prominence as an associated cardiovascular disease (CVD) risk factor, often thought to be an issue in colder climates and higher altitudes. The intent of this study was to ascertain vitamin D levels in the southern Alabama gulf-coast region that has a high number of ...
Song Tae-Jin TJ From the Departments of Neurology (T.-J.S., D.S., H.S.N., Y.D.K., J.H.H.) and Biostatistics (H.S.L.), Yonsei University College of Medicine, Seoul; Department of Neurology (T.-J.S.), Ewha Womans University School of Medicine, Seoul; and Department of Neurology (J.K.), CHA Bundang Medical Centre, CHA University, Seongnam, - - 2014
We investigated the association of cerebral microbleeds (CMBs) with long-term mortality in patients with nonvalvular atrial fibrillation (NVAF) according to burden and distribution of CMBs. This was a retrospective, hospital-based, observational study. In total, 504 consecutive ischemic stroke patients with NVAF who underwent brain T2-weighted, gradient-recalled echo MRI were included. ...
Vanassche Thomas T Population Health Research Institute, McMaster University and Hamilton Health Sciences, 237 Barton St. E., Hamilton, ON, Canada L8L 2X2 - - 2014
The pattern of atrial fibrillation (AF) occurrence-paroxysmal, persistent, or permanent-is associated with progressive stages of atrial dysfunction and structural changes and may therefore be associated with progressively higher stroke risk. However, previous studies have not consistently shown AF pattern to predict stroke but have been hampered by methodological shortcomings of ...
Costantini Antonio A Department of Neurological Rehabilitation, Clinic "Villa Immacolata ," Viterbo, Italy - - 2014
Abstract Background and objectives: A previous study on fatigue and related disorders in inflammatory bowel disease, patients improved after therapy with high-dose thiamine. Chronic fatigue that accompanies inflammatory and autoimmune diseases could be the clinical manifestation of a mild thiamine deficiency, probably due to a dysfunction of intracellular transport or ...
Larsen Torben Bjerregaard TB Department of Cardiology, Aalborg Atrial Fibrillation Study Group, Aalborg University Hospital, Denmark; Aalborg Thrombosis Research Unit, Department of Clinical Medicine, Faculty of Health, Aalborg University, Aalborg, Denmark. Electronic address: - - 2014
This register-based observational study compares dabigatran to warfarin for secondary stroke prevention in atrial fibrillation patients among both 'new starters' on dabigatran and 'switchers' to dabigatran from warfarin. We identified in nationwide Danish registries 2,398 patients with atrial fibrillation and a history of stroke/TIA, making a first-time purchase of dabigatran ...
Tehrani Setareh S Assistant professor, Dermatologist, Islamic Azad University of Tehran, Medical branch, Tehran, - - 2014
To determine the prevalence of seborrhoeic dermatitis (SD) and atopic dermatitis (AD) between the Demodex folliculorum (D. folliculorum) positive and D. folliculorum negative patients and to investigate any possible relationship between the D. folliculorum mites and the presence of SD and AD. In this cross sectional study, authors collected samples ...
Shih Hong-Mo HM Department of Emergency Medicine, Chang Gung Memorial Hospital, Chiayi and Chang Gung University College of Medicine, Puzi City, Chiayi County, Taiwan - - 2014
Thiazides have been used for the control of blood pressure and primary prevention of ischemic stroke. No previous studies have assessed the influence of thiazides on functional prognosis after ischemic stroke. Demographics, prestroke conditions, poststroke National Institutes of Health Stroke Scale score, and clinical and laboratory parameters were prospectively registered ...
Kim Bum Joon BJ Department of Neurology, Asan Medical Center, Seoul, - - 2014
Neuron-specific enolase (NSE) is a surrogate marker for the extent of brain damage after ischemic stroke and affords a good predictor of stroke prognosis. We hypothesized that the pattern of NSE level changes in the peripheral blood during the acute period of ischemic stroke is dependent on stroke mechanism and ...
Jang Sung Ho SH Department of Physical Medicine and Rehabilitation, College of Medicine, Yeungnam University , Daegu , Republic of - - 2014
Abstract We investigated change of the anterior corticospinal tract (CST) on the normal side of the brain in stroke patients, using diffusion tensor tractography (DTT). We recruited 32 stroke patients and 24 control subjects. Motricity Index and DTT for the whole and anterior CSTs were evaluated. According to findings, the ...
Hansen Anne P AP Danish Pain Research Center, Aarhus University Hospital, Aarhus, Denmark - - 2014
Headache following stroke has been described in previous studies with an incidence of 23%-54%, but a clear description of headache developing after stroke onset is still lacking. The aim of this study was to determine the incidence and characteristics of persistent novel headache after stroke and to describe the use ...
Saarinen Jukka T JT School of Medicine, University of Tampere, Tampere, Finland. Electronic address: - - 2014
The purpose of this study was to observe adherence to antithrombotic management guidelines among atrial fibrillation (AF) patients and to determine prognostic factors for 3-month mortality in both ischemic and hemorrhagic stroke patients with or without AF. This was a retrospective observational single stroke center cohort study. In 2007, 380 ...
Wang Xianwei X Neurology, Beijng Tiantan Hospital, Capital Medical University, Beijing, - - 2014
the impact of estimated glomerular filtration rate (eGFR) on stroke clinical outcomes remains controversial. We examined the association between eGFR and all-cause mortality, recurrent stroke, and stroke disability in patients with acute ischaemic stroke. we analysed 8865 patients with acute ischaemic stroke in the China National Stroke Registry (CNSR) between ...
Gökdeniz Tayyar T Department of Cardiology, Faculty of Medicine, Kafkas University, Kars, - - 2014
Background: Chronic obstructive pulmonary disease (COPD) is not only characterized by chronic airflow limitation, but is also a systemic disease. There is no information about alterations in right ventricle (RV) functions precipitated by systemic manifestations of COPD. Objectives: We aimed to evaluate the relationship between the BODE (body mass index, ...
He Xiaoxuan X aCenter for Biomedical Engineering, University of Science and Technology of China bLaboratory of Digital Medical Imaging, Medical Imaging Center, The First Affiliated Hospital, Anhui University of Chinese Medicine, Hefei, Anhui, China cDepartment of Biomedical Engineering, Kyung Hee University, Yongin, Republic of - - 2014
Bell's palsy is the most common cause of acute facial nerve paralysis. In China, Bell's palsy is frequently treated with acupuncture. However, its efficacy and underlying mechanism are still controversial. In this study, we used functional MRI to investigate the effect of acupuncture on the functional connectivity of the brain ...
Elmariah Sammy S Cardiology Division, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts; Harvard Clinical Research Institute, Boston, - - 2014
This study sought to identify predictors of recurrent ischemic neurologic events within the CLOSURE I (Evaluation of the STARFlex Septal Closure System in Patients With a Stroke and/or Transient Ischemic Attack Due to Presumed Paradoxical Embolism Through a Patent Foramen Ovale) trial. The CLOSURE I trial found that transcatheter patent ...
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