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Björkman Eleonora Victoria Charlotta - - 2013
Abstract Background and aims. Gastroesophageal reflux disease (GERD) is associated with impaired epithelial barrier function. However, the influence of acid and/or bile acids on human esophageal epithelial barrier function and the tight junction (TJ) proteins has not been fully elucidated. The aim of the study is to investigate the esophageal ...
Verma Rajesh - - 2013
Guillain-Barre syndrome (GBS) is an acute polyradiculoneuropathy with varied severity of presentation. To study the clinical and electrophysiological profile of patients with GBS and to determine the factors associated with poor functional outcome and need for mechanical ventilation. It was a hospital-based prospective observational study. 90 patients with GBS diagnosed ...
Andrea Rut - - 2013
Heart failure with preserved ejection fraction (HFPEF) is the most prevalent form of heart failure in outpatients. Yet, the pathophysiology of this syndrome is unclear and pharmacological treatment does not improve prognosis. Because breathlessness during activities of daily living is the most frequent complaint of patients with HFPEF, we hypothesised ...
Lee Seojung S Department of Psychiatry and Institute of Behavioral Science in Medicine, Yonsei University College of Medicine, Seoul, Republic of - - 2013
Alcohol dependence is characterized by persistent alcohol-seeking despite negative consequences. Previous studies suggest that maladaptive persistent behaviors reflect alcohol-induced brain changes that cause alterations in the cortico-striatal-limbic circuit. Twenty one alcohol dependent patients and 24 age-matched healthy controls performed a decision-making task during functional MRI. We defined the medial orbitofrontal ...
Sato Emiko - - 2013
It is important to understand dysphagia in patients with dementia, as it is associated with malnutrition and aspiration pneumonia. Particularly in patients with Alzheimer's disease (AD), mortality from pneumonia is high and accounts for 70% of the causes of death. However, the standard swallowing tests are often difficult to use ...
Eom Jung Seop - - 2013
Although elongated morphological changes in the trachea are known to be related to lung function in chronic obstructive pulmonary disease (COPD), whether the tracheal morphological changes are associated with airflow limitations or overinflation of the lung in the early stages of COPD has not yet been determined. Thus, our aim ...
Foster Paul S - - 2013
The cerebral hemispheres are differentially involved in regulating immunological functioning and the neuropathology associated with Alzheimer's disease (AD) is asymmetrical. Thus, subgroups of AD patients may exhibit different patterns of immunological dysfunction. We explored this possibility in a group of AD patients and found that patients with low white blood ...
Fernandes Alessandro Murano Ferré - - 2013
Multiple sclerosis is a neurological disease that involves swallowing disorders. Many studies have shown an association between neurological and swallowing performance, but results have been conflicting. To identify the frequency of dysphagia in patients with multiple sclerosis and neurological indicators that can represent the performance of swallowing. In this study ...
Aizawa Carolina Yuri P - - 2013
To assess balance and ability to function in patients with spinocerebellar ataxia. A total of 44 patients with different spinocerebellar ataxia types 1, 2, 3, and 6 were evaluated using the Tinetti balance and gait assessment and the functional independence measure. The scale for the assessment and rating of ataxia ...
Brittain Evan L - - 2013
We hypothesized that RV stroke work index (RVSWI) and pulmonary capacitance (PC) would increase after treatment for pulmonary arterial hypertension (PAH) and that prostanoids would have a stronger effect than oral therapy. Right ventricular (RV) function is a major determinant of outcome in patients with PAH. Little is known about ...
Alary Mathieu - - 2013
It is widely reported that patients with schizophrenia exhibit decreased hemispheric lateralization. However, no study has evaluated relationships between the hemispheric anatomical and functional asymmetry in language areas. The present study aimed to determine whether decreased leftward hemispheric lateralization could be related to asymmetry of the grey matter volume in ...
Chern Jen-Suh - - 2013
The purpose was to examine the effects of static anterior and posterior ankle-foot orthoses (AAFOs & PAFOs) using with regular shoes on improving static and gait function in patients recovering from stroke. Static and dynamic balance control were measured under four conditions: barefeet, wearing regular shoes only, and wearing regular ...
Cha Jungho J Department of Biomedical Engineering, Hanyang University, Seoul, South - - 2013
Most default mode network (DMN) studies in patients with amnestic mild cognitive impairment (aMCI) and Alzheimer's disease (AD) are based on the comparison of only two groups, namely patients and controls. Information derived from comparing three groups, normal, aMCI and AD, simultaneously may lead us to better understand the progression ...
Valderramas Silvia S Faculdade Dom - - 2013
To describe the intra-rater and inter-rater reliability of the Brazilian Portuguese version of the fatigue severity scale (FSS) in patients with COPD and to identify the presence of its association with parameters of pulmonary function, dyspnea, and functional capacity. This was an observational cross-sectional study involving 50 patients with COPD, ...
Oertel-Knöchel Viola - - 2013
The planum temporale (PT) is a highly lateralized brain area associated with auditory and language processing. In schizophrenia, reduced structural and functional laterality of the PT has been suggested, which is of clinical interest because of its potential role in the generation of auditory verbal hallucinations. We investigated whether resting-state ...
Arslan U─čur - - 2013
OBJECTIVE: Cardiac resynchronization therapy (CRT) improves heart rate variability (HRV) and heart rate turbulence (HRT) parameters. Herein, our aim was to compare these parameters with intracardiac- cardioverter defibrillator (ICD) patients with similar functional status to detect possible additional benefits of CRT on autonomic functions. METHODS: Patients who had systolic HF ...
Leblanc A - - 2013
Asthma is a complex disease with numerous markers of severity/activity. Clinical assessment,functional parameters and inflammation biomarkers are the most used A correlation between them is difficult, as each one evaluates a particular aspect of the disease. To explore the possible association between asthma control, pulmonary function and inflammation in patients ...
Zhang S S - - 2013
Conventional total superficial parotidectomy (TP) has commonly been used, but partial superficial parotidectomy (PP) offers the possibility of better preserving glandular function and avoiding palsy of the facial nerves. In this study, the extent to which saliva secretion and facial nerve function were conserved in patients who received TP vs. ...
Tarapore Phiroz E PE Department of Neurological Surgery, University of California, San Francisco, California 94107-0946, - - 2013
Traumatic brain injury (TBI) is one of the leading causes of morbidity worldwide. One mechanism by which blunt head trauma may disrupt normal cognition and behavior is through alteration of functional connectivity between brain regions. In this pilot study, the authors applied a rapid automated resting state magnetoencephalography (MEG) imaging ...
Jeong Shin Young SY Department of Nuclear Medicine, Kyungpook National University School of Medicine/Hospital , Daegu, - - 2013
Chronic sialadenitis is one of the most frequent chronic complications after radioactive iodine (RAI) therapy for thyroid cancer. To evaluate the long-term effects of RAI ablation on salivary gland function, we investigated scintigraphic changes in salivary glands by direct comparison of two salivary gland scintigraphies (SGSs) taken before and at ...
Solovykh E A - - 2013
Analysis of correlations of the functional parameters of the stomatognathic and postural systems with sub-, decompensated, and compensated status was carried out. Disorders in the masticatory muscle activity and interactions between the postural and stomatognathic systems were detected in patients with sub- and decompensated functional status. A significant correlation between ...
Ben Fredj H - - 2013
Background: The rheumatoid polyarthritis (PR) is a frequent pathology in Tunisia. The most frequent extra articular expression of this disease is in the respiratory tract. aim: To determine the lung functional profile of PR of the Tunisian population by establishing possible relations between ventilatory variables and clinico-biological parameters of PR. ...
Gatta G - - 2013
The purpose of the study was to identify the correlation between functional lung parameters to the extent of lung involvement evaluated by High Resolution Computed Tomography (HRCT) in systemic sclerosis (SSc), using a modified score scale. Forty-two patients with established clinical diagnosis of systemic sclerosis were retrospectively selected from the ...
Komuro Ayako - - 2013
Cerebellar stroke rarely causes disorders of higher brain function such as cognitive deficits and emotional dysfunction; hence, the prognosis of these patients is uncertain. We report the case of a 34-year-old patient with cerebellar hemorrhage due to arteriovenous malformation causing higher brain dysfunction who was able to return to full-time ...
Tjora E - - 2013
OBJECTIVES: To examine the exocrine pancreatic function in carriers of the hepatocyte nuclear factor 1β gene (HNF1B) mutation by direct testing. METHODS: Patients with HNF1B mutations and control subjects were assessed using rapid endoscopic secretin tests and secretin-stimulated magnetic resonance imaging. Seven patients and 25 controls underwent endoscopy, while eight ...
Lin Hui - - 2013
Lung injury commonly accompanies uremia caused by renal failure. Uremia is typically treated using hemodialysis (dialysis) to restore electrolyte and fluid balance. A more recent, less commonly used method, high-flux dialysis, has not yet been investigated for its potential benefit to lung function. The aim of the present study was ...
Jang Sung Ho - - 2013
Somatosensory dysfunction is associated with a high incidence of functional impairment and safety in patients with stroke. With developments in brain mapping techniques, many studies have addressed the recovery of various functions in such patients. However, relatively little is known about the mechanisms of recovery of somatosensory function. Based on ...
Kon Valentina - - 2013
PURPOSE OF REVIEW: This review will examine advances in our understanding of the association between high-density lipoprotein (HDL) function and cardiovascular disease (CVD) in patients with chronic kidney disease (CKD). RECENT FINDINGS: Large randomized statin trials and related meta-analyses confirm that lipid-lowering therapy benefits patients with mild to moderate CKD, ...
Nanashima Atsushi - - 2013
OBJECTIVES: The aim of the study was to clarify the clinical significance of single-photon emission computed tomography/computed tomography (SPECT/CT) imaging in terms of technetium-99m galactosyl human serum albumin (Tc-GSA) scintigraphy. To this end, we examined the relationship using data from surgical records of 67 patients with hepatocellular carcinoma who underwent ...
Aframian Doron J - - 2013
Salivary gland impairment after radioiodine therapy (RIT) is a well-known iatrogenic artifact that includes recurrent episodes of sialadenitis, hyposalivation, dysgeusia, and dysphagia. Several therapy modalities have been suggested over the years to decrease these effects on the salivary glands. However, in cases where the salivary gland system is impaired prior ...
Yin Dazhi - - 2013
INTRODUCTION: Previous studies of task-based functional neuroimaging have shown that various patterns of functional reorganization underlie motor recovery following stroke. However, the mechanisms underlying functional reorganization that contribute to outcome differences in hand function after stroke have not been completely characterized. We, for the first time, investigate subgroups of stroke ...
Alonso-Gonzalez Rafael - - 2013
BACKGROUND: Restrictive lung defects are associated with higher mortality in patients with acquired chronic heart failure. We investigated the prevalence of abnormal lung function, its relation to severity of underlying cardiac defect, surgical history and its impact on outcome across the spectrum of adult congenital heart disease (ACHD). METHODS AND ...
Ward Michael M MM National Institute of Arthritis and Musculoskeletal and Skin Diseases, NIH, Bethesda, MD 20892-1468, USA. - - 2013
Both radiographic damage and functional limitations increase with the duration of ankylosing spondylitis (AS). We examined whether radiographic damage contributed more to functional limitations in late AS than in early AS, and if the strength of association varied with the anatomic region of damage. In this cross-sectional study of 801 ...
Gupta Neelima - - 2013
Nasal nitric oxide (NO) and olfactory function are decreased in patients with chronic inflammatory sinonasal disease, suggesting a link between these two parameters. The aim of the study was to investigate nasal NO levels in patients with olfactory dysfunction due to different causes. Prospective study in a university clinic setting ...
Likhi Moorkoth - - 2013
Background: Attainment of functional independence is the ultimate goal of a sound stroke rehabilitation program. Good trunk stability is essential for balance and extremity use. Stroke patients may have upper extremity impairments that may affect functional activity and lower extremity impairments that may hinder mobility. Hence, quantifying the specific levels ...
Falkenstern-Ge R F - - 2013
Endoscopic lung volume reduction using lung sealant is a very new and innovative treatment option for patients with severe progressive and irreversible lung emphysema. A 55-year-old ex-smoker (60 pack years) referred to our center because of severe lung emphysema with progressive worsening of the obstructive ventilator pattern and clinical condition. ...
Lobet Sébastien - - 2013
In patients with haemophilia (PWH) (from Greek "blood love"), the long-term consequences of repeated haemarthrosis include cartilage damage and irreversible arthropathy, resulting in severe impairments in locomotion. Quantifying the extent of joint damage is therefore important in order to prevent disease progression and compare the efficacy of treatment strategies. Musculoskeletal ...
Zhang Long Jiang - - 2013
To evaluate the changes of functional connectivity of the anterior cingulate cortex (ACC) in patients with cirrhosis without overt hepatic encephalopathy (HE) using resting state functional MRI. Participants included 67 cirrhotic patients (27 minimal hepatic encephalopathy (MHE) and 40 cirrhotic patients without MHE (non-HE)), and 40 age- and gender- matched ...
Jarenbäck Linnea - - 2013
Classification of COPD into different GOLD stages is based on forced expiratory volume in 1 s (FEV1) and forced vital capacity (FVC) but has shown to be of limited value. The aim of the study was to relate spirometry values to more advanced measures of lung function in COPD patients compared ...
Galeiras Vázquez Rita - - 2013
Spinal cord injuries (SCIs) often lead to impairment of the respiratory system and, consequently, restrictive respiratory changes. Paresis or paralysis of the respiratory muscles can lead to respiratory insufficiency, which is dependent on the level and completeness of the injury. Respiratory complications include hypoventilation, a reduction in surfactant production, mucus ...
Ilic Sanja - - 2013
Background The aim of this study was to investigate left ventricular (LV) and right ventricular (RV) structure, function, and mechanics in patients with subclinical hypothyroidism (SHT), and to evaluate the effect of a 1-year levothyroxine treatment. Material and Methods We compared 45 untreated women with subclinical hypothyroidism and 35 healthy ...
Antony Arun R - - 2013
This project aimed to determine if a correlation-based measure of functional connectivity can identify epileptogenic zones from intracranial EEG signals, as well as to investigate the prognostic significance of such a measure on seizure outcome following temporal lobe lobectomy. To this end, we retrospectively analyzed 23 adult patients with intractable ...
Mäki-Marttunen Verónica V Department of Cognitive Neuroscience, Institute for Neurological Research, FLENI Buenos Aires, Argentina ; CONICET Buenos Aires, - - 2013
Severe traumatic brain injury can lead to disorders of consciousness (DOC) characterized by deficit in conscious awareness and cognitive impairment including coma, vegetative state, minimally consciousness, and lock-in syndrome. Of crucial importance is to find objective markers that can account for the large-scale disturbances of brain function to help the ...
Pietraszko Wojciech W Department of Neurosurgery, Jagiellonian University Medical College, Krakow, - - 2013
Subthalamic nucleus (STN) deep brain stimulation (DBS) is well established for the treatment of the motor symptoms of Parkinson's disease (PD). However, the effect of STN DBS on autonomic symptoms has not been well studied. We examined 19 patients undergoing STN DBS for PD. The patients were administered a questionnaire ...
Selvi E Chandra C Assistant Professor, Department of Physiology, Sree Balaji Medical College , Chrompet, Chennai, India - - 2013
The functional residual capacity was given the least importance than the other lung volume parameters. Studies have revealed the restrictive pattern of lung disease in patients with liver cirrhosis. We aimed to analyze the importance of the functional residual capacity and other lung volumes of cirrhotic patients. Forty (40) patients ...
Fang Tie - - 2012
Functional connectivity is altered in several mental disorders. We used resting-state functional MRI to examine the alterations in functional connectivity that occur in patients with absence epilepsy. We found an altered functional connectivity within and between functional modules in patients with absence epilepsy. Some brain regions had a greater number ...
Rajabally Yusuf A - - 2012
BACKGROUND: Few studies have evaluated the functional and electrophysiological correlates of hand-held grip dynamometry in neuromuscular disease. The practical value of normative values remains uncertain in clinical practice. We aimed to ascertain the value, clinical and electrophysiological correlates, as well as utility of normative values for grip dynamometry, in a ...
Penafortes J T S - - 2012
AIM: The purpose of this study was to evaluate the correlations within pulmonary function, functional capacity, and posture in adult patients with cystic fibrosis (CF). A secondary aim was to evaluate the correlation between patient quality of life and postural assessment variables. METHOD: A cross-sectional study was conducted on fourteen ...
Huang H C - - 2012
BACKGROUND: Functional outcome and the risk factors for stroke survivors have explored in previous study. However, a comprehensive understanding of the patterns and critical risk factors of functional recovery is limited. AIM:To explore the trajectory groups and determinants of functional recovery for ischemic stroke patients during 1 year after stroke. ...
Holtslag Irene - - 2012
Purpose: To evaluate all functional aspects of patients with longitudinal radial dysplasia and to clarify the relationship between body functions on the one hand and limitations in activity and participation on the other hand. Methods: Thirty-one arms of seventeen adult patients with longitudinal radial dysplasia were analysed. Body function was ...
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