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Cleghorn J M - - 1989
Frontal and parietal lobe metabolism was measured by [18F] fluorodeoxyglucose positron emission tomography in 8 never-medicated DSM-III schizophrenic patients and in 10 control subjects. Patients were in a psychotic episode at the time of this scan. Seven of eight had been ill less than 2 years and had only mild ...
Mitchell J - - 1989
Delusions and hallucinations reported in the social histories of 150 patients admitted to an East Texas state hospital during the 1930s and of 150 patients admitted during the 1980s were examined for content that would characterize and contrast the patient subcultural milieu of the two time periods. Patients admitted during ...
Heath R G - - 1989
On the hypothesis that schizophrenia is an immunological disorder in which antibody is produced against a unique antigen sequestered principally or exclusively in the septal region of the brain, we used crossed-immunoelectrophoresis (CIE) to evaluate reactivity of a gamma G immunoglobulin (IgG) fraction from serum of schizophrenic patients and nonschizophrenic ...
Schwarzkopf S B - - 1989
History of perinatal complications (PCs) and first degree family history (FH) of psychiatric illness were examined in groups of schizophrenic/schizoaffective (n = 21) and bipolar (n = 10) patients. PCs were significantly more frequent in the schizophrenic and schizoaffective patients than in bipolar patients. An inverse relationship was found between ...
Koczapski A - - 1989
The present study replicates that of De Freitas and Schwartz (1979), using more typical chronic patients (on open wards rather than locked wards), and monitoring coffee intake with serum caffeine levels. The serum caffeine levels observed indicate that caffeine can be effectively manipulated on an open ward by switching the ...
Robert P - - 1989
The aim of this study was to compare the evolution of psychotic patients in Algeria and in France. In 1975, 105 patients were selected in Algeria and 237 in France. Ten years later, in 1985, all these patients were interviewed. In 1985, we investigated for each subject the evolution of ...
Kornhuber J - - 1989
In post-mortem putamen samples from 27 schizophrenics and 27 controls D2 receptors were measured by Scatchard analysis using 3H-spiperone as a ligand. Maximum number of binding sites (Bmax) and apparent dissociation constant (KD) were significantly increased only in patients in whom neuroleptic medication had been given within a three-month period ...
Patki A H - - 1989
Three hundred and sixty six in-patients in a leprosy hospital were examined for other dermatological conditions. Eighty eight of them displayed ichthyosiform changes. A peculiar condition of a verrucous hyperkeratotic growth on the anterior aspect of ankle, not described previously, was observed in four patients. It was noted that 11 ...
Ghei S K - - 1989
Palmar configurations of triradii and creases of 100 leprosy patients [50 lepromatous (BL/LL) and 50 tuberculoid (BT/LL)] were compared with those of 100 normal persons selected from families of these patients. The patterns of position of triradii were similar in controls and leprosy patients as such. But, the patterns in ...
Vieira R - - 1989
Plasma benzylamine oxidase (BzAO) activity was analysed in a group of 40 schizophrenic patients and compared with that of healthy controls. Although plasma BzAO was significantly decreased in schizophrenics as a whole, when patients were divided into type I (favourable course) and type II (poor course) it was found that ...
Westermeyer J - - 1989
Delusions of fatal contagion were encountered in about 10% of refugee psychiatric patients from Southeast Asia belonging to one ethnic group, the Hmong. Psychotic depression was the most common diagnosis among the Hmong patients with delusions of contagion, whereas paranoid and schizophrenic diagnoses predominate in patients with similar delusions from ...
Gureje O - - 1988
There are conflicting reports about factors that may be associated with the development of involuntary movements in patients exposed to long-term neuroleptic treatment. Recent evidence suggests that some of these inconsistencies may relate to the practice of regarding these disorders as a unitary syndrome. There is also evidence that both ...
Gureje O - - 1988
The prevalence of neurological soft signs in schizophrenics was compared with that in patients with major affective disorder and in normal subjects. The two patient groups did not differ from one another, but both differed from normal controls in the occurrence of right-left confusion. The paranoid and nonparanoid subtypes of ...
Wode-Helgodt B - - 1988
Twelve schizophrenic patients were treated with neuroleptic drugs and psychoanalytically oriented group therapy during a period of 2 years. Twelve other patients, matched with regard to the state of their disease, sex, age, civil status and social situation, were given neuroleptic drugs and contact therapy during the same period. All ...
West B C - - 1988
Northern Louisiana has been essentially free of indigenous leprosy, and now it is not. Six new cases of leprosy have been diagnosed: three in 1986, the other three in 1985, 1983, and 1982, respectively. The patients had been lifelong residents of six scattered rural parishes. Leprosy had never been reported ...
Brown P J - - 1988
As part of an ongoing longitudinal study of drug-free schizophrenic patients, we serially sampled resting early morning prolactin levels in 10 subjects. In a preliminary analysis, these levels were compared to those found in matched normal control subjects over a 4-year period. Both control and schizophrenic subjects showed a marked ...
Raj P P - - 1988
The half time of disappearance of dapsone and monoacetyl dapsone and the acetylator phenotype of the leprosy patients who harboured dapsone sensitive and dapsone resistant M. leprae was assessed in 27 subjects. Sixteen patients were rapid acetylators, five were slow and six were intermediate acetylators. The mean T 1 1/2 ...
Tandon R - - 1988
In an effort to investigate reports of possible benefits of trihexyphenidyl on residual schizophrenic symptoms, the drug was administered to five chronic schizophrenic patients with predominantly negative symptoms. These patients were simultaneously receiving various antipsychotic agents without extrapyramidal side effects. There was a marked improvement in four of the five ...
Hodes R M - - 1988
It has long been noted that tetanus is rare in leprosy patients. Five cases of tetanus are reported in leprosy patients in Addis Ababa, Ethiopia. Although natural immunity to tetanus occurs and this appears to be higher in leprosy patients than in the general population, it is not completely protective. ...
Lawson W B - - 1988
Twenty-seven chronic schizophrenic patients and nine other psychiatric patients closely matched in education were compared on the Halstead-Reitan Battery and the Wechsler Adult Intelligence Scale (WAIS). The schizophrenic patients as a group showed significantly poorer performance on the WAIS (full scale: X +/- SD, 92.9 +/- 2.9 vs. 110.8 +/- ...
Fukushima J - - 1988
To study whether or not schizophrenic patients have disturbances in voluntary control of saccades, we examined visually elicited saccade and antisaccade tasks in 10 normal control subjects and 12 schizophrenic patients. The latencies of saccades in the schizophrenic patients were not significantly different from those of normal controls. However, 6 ...
Marneros A - - 1988
The nonpsychopathological features of 107 patients diagnosed as having mania were compared to those of 1,208 patients with the diagnosis of schizophrenia. Both diagnoses were made according to K. Schneider's criteria. Significant differences were found between the two groups in regard to the age of onset, marital status and educational ...
Josiassen R C - - 1988
Evoked potentials (EPs) of schizophrenic patients differ from those of normal controls and some other diagnostic groups, but EP measurements of the comparison groups often overlap considerably. This suggests that schizophrenics are heterogeneous with respect to EP measurements and that additional methods for clinical subtyping are needed to account for ...
Vieweg W V - - 1988
We found diurnal weight gain to be abnormal among 65 long-term patients with schizophrenic disorders. Patients were weighed at 7 a.m. and 4 p.m. serially and diurnal weight gain was normalized (NDWG) as a percentage by subtracting the 7 a.m. weight from the 4 p.m. weight, multiplying the difference by ...
Lyon N - - 1988
Some theoretical implications from a CNS stimulation model of psychosis were tested by analysing the response patterns of schizophrenic (N = 34), affective disorder patients (N = 18), schizoid personality disorder patients (N = 9), neurotic patients (N = 9) and normal controls (N = 34) on a visual two-choice ...
Haselhorst U - - 1988
The pattern of gangliosides in membranes of erythrocytes was examined in healthy donors, in acute schizophrenics without neuroleptic treatment and in alcohol-dependent patients. 7 different gangliosides could be detected. Healthy donors were characterized by the following ganglioside pattern: GX = 5.8%; GT1b = 6.7%; FucGD1b = 5.2%; GD1a = 12.6%, ...
Koumantaki I G - - 1987
To investigate if early exposure to Mycobacterium leprae is a factor determining development of Hansen's disease in general, or of a particular form of the disease, we have studied the sibship size and birth order distribution of 187 leprosy cases and 528 hospitalized control patients. By the Greenwood-Yule analysis, a ...
Frith C D - - 1987
The CNS maintains a fundamental distinction between actions elicited by external stimuli and actions elicited by internal goals (acts of will). As a result the intact organism can monitor centrally three aspects of its own actions: (1) the action appropriate to current external stimulation (stimulus intention or meaning); (2) the ...
Menza M A - - 1987
In a preliminary, prospective study, the intensity of extrapyramidal symptoms was rated in four patients receiving intravenous haloperidol and six patients receiving oral haloperidol. The raters were blind to the route of administration. In this pilot study, the first systematic evaluation of intravenous haloperidol and extrapyramidal symptoms, the patients receiving ...
Tarrier N - - 1987
Twenty-five patients who had been discharged back into the community after an acute schizophrenic episode but who still experienced residual psychotic symptoms were interviewed to elicit the antecedents, consequences and coping strategies of their symptoms. Fifty-two per cent were able to identify antecedent stimuli and 92 per cent still experienced ...
McClelland H A - - 1987
An ultrasound detector (UD) was compared with a clinical rating (CR) scale in the assessment of oro-facial movements in 23 chronic schizophrenic patients and 23 normal subjects over a period of 4 weeks. The apparatus distinguished well between normal volunteers and dyskinetic patients. There were also highly significant correlations between ...
- - 1987
Forty-nine first episode schizophrenics were identified and considered to be representative of the parent schizophrenic population. Patients were rated before treatment with the Present State Examination. Findings are presented with regard to Catego classes, prevalence of first rank symptoms, conformity to ICD diagnoses, Feighner and Research Diagnostic Criteria and presence ...
Matsuo T - - 1987
The condition that a part of the digestive tract interposes between the liver and diaphragm has been called Chilaiditi's syndrome. Although it has been reported that this condition had a higher rate of incidence in patients of mental hospitals than in other individuals, there are hardly any enlightening papers of ...
Bick P A - - 1987
Fourteen of 18 hallucinating schizophrenic patients reported that the voices they heard went away when they undertook a maneuver that precluded subvocalization. The same applied to 18 of 21 normal subjects who hallucinated under the influence of hypnotic suggestion. Control maneuvers had no such effect. The authors suggest that auditory ...
Youssef H A - - 1987
A population of 101 chronic schizophrenic inpatients were assessed for the presence or absence of tardive dyskinesia, and followed up 32 months later. At follow up, the mortality rates in 44 patients with and 57 patients without involuntary movements were 16% vs. 9% respectively; this difference widened when only the ...
Kumar V - - 1987
Pharmacokinetic, therapeutic effects, and side effects of nortriptyline were studied in geriatric depressed patients treated with a standard dose of 150 mg/day. Plasma levels and elimination half-life of nortriptyline were no different in geriatric patients than younger patients. The antidepressant therapeutic effects of nortriptyline appeared to be similar in geriatric ...
Gambini O - - 1987
Performances of 59 affective patients, 59 schizophrenics and 59 normal controls on the Quality Extinction Test (QET), which has been proven to be valuable for detecting abnormal hemisphere functioning in neurological and psychiatric patients, are presented. Frequencies of the left and right extinctions of the affective patients did not exceed ...
Shenton M E - - 1987
We examined thought disorder in 22 patients with schizoaffective disorder (12 schizoaffective-manic and ten schizoaffective-depressed) using Research Diagnostic Criteria. The Thought Disorder Index was used to tag 22 categories of thought disorder that ranged from mild to severe. Qualitative patterns in the thought disorder of schizoaffective patients were compared with ...
Matsuoka I - - 1986
The effects of bromocriptine on neuroleptic-induced endocrinological disturbances (amenorrhea, galactorrhea and impotence) were investigated. Bromocriptine (5.0-7.5 mg/day) was administered to psychiatric patients receiving neuroleptics and developing hyperprolactinemia. The following results were obtained. Menses recurred in 7 of 10 patients with amenorrhea. A decrease in lactation appeared in 5 of 6 ...
Guenther W - - 1986
In this investigation we examined eight Type I (positive symptoms without marked negative symptomatology), eight Type II (marked negative symptoms) schizophrenic patients of the disordered and paranoid diagnostic subgroups (DSM-III 295.1 and 295.3), eight severely (HAMD above 35) and eight less severely (HAMD below 20) endogenous depressed patients, and eight ...
Wagener D K - - 1986
Tests of attention/information processing, the continuous performance test (CPT) and the span of apprehension task (SAT), were given to 25 schizophrenic patients and their mothers. Measures of communication deviance also were obtained from the mothers. Comparison of these assessments in the mothers revealed different transactional profiles for good attenders and ...
Friis S - - 1986
On 35 short-term wards the connection between ward atmosphere as perceived by patients and various setting and treatment characteristics was explored by the use of a hierarchical multiple regression analysis. The most important variables proved to be: mean age of patients, percentage of psychotic patients, number of patients, staff turnover ...
Chamove A S - - 1986
Forty schizophrenic patients were rated both by nurses (using the NOSIE) and by themselves on days soon after they had completed a period of activity. When compared with less active days, significant improvement was seen in most behaviours measured following activity, suggesting that activity is beneficial in the treatment of ...
Rohatgi J - - 1986
A total of 424 leprosy patients were screened for uveal involvement. Uveal changes were found in 11.2% of these patients. Uveal involvement was more common in patients with greater duration of the disease and in patients on irregular Dapsone therapy. Of the patients with uveal involvement 82% were lepromatous, 16% ...
Martinos A - - 1986
In order to investigate the effects of 6 weeks' neuroleptic treatment on the pituitary-thyroid axis in 25 male schizophrenic patients, and the diurnal variation in the thyrotropin (TSH) and prolactin (PRL) responses to thyrotropin-releasing hormone (TRH) in these patients, the TRH stimulation test was performed in each of them at ...
Günther W - - 1986
This study investigates the existence and course of psychomotor symptoms in schizophrenic patients (n = 57, both treated and untreated with antipsychotic drugs) as compared to 25 healthy controls. Previous psychometric studies had suggested the existence of a "psychotic motor syndrome" (PMS) both in (untreated) schizophrenic and endogenous depressed patients, ...
Goetz K L - - 1986
Since the initial reports of ventricular enlargement in schizophrenics, attempts have been made to define a subgroup of patients with brain atrophy on computerized axial tomography (CAT) scans. The authors reviewed this literature for clinical, biochemical, and environmental correlates of lateral and third ventricular enlargement as well as cortical and ...
Berndl K - - 1986
The perception and recognition of faces, mimic expression and gestures were investigated in normal subjects and schizophrenic patients by means of a movie test described in a previous report (Berndl et al. 1986). The error scores were compared with results from a semi-quantitative evaluation of psychopathological symptoms and with some ...
McGlashan T H - - 1986
This report elaborates the long-term course and outcome for systematically rediagnosed patients with borderline personality disorder (n = 81) from the Chestnut Lodge follow-up study. They were assessed and are described from multiple outcome perspectives. Schizophrenic (n = 163) and unipolar affective disorder (n = 44) cohorts serve for comparison. ...
Dehlin O - - 1986
The hypnotic effect of chlormethiazole was studied for 3 months in 20 geriatric in-patients. Registered variables were the percentage of patients asleep at 10 pm and 6 am and the observed number of awakenings. Mental and somatic variables were rated according to the Crichton Geriatric Behavioural Rating Scale. Observations were ...
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