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Results 551 - 571 of 571
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Pacquay M - - 1976
The effect of higher than usual dosages of haloperidol was studied in 38 chronic institutionalized schizophrenic patients for whom any hope of discharge had been abandoned. In 23 patients (61%) a marked or moderate improvement was observed. No striking differences were seen between patients simultaneously receiving or not receiving group ...
Whittaker M - - 1976
Blood samples from 580 African leprosy patients living in Rhodesia have been phenotyped for the plasma cholinesterase variants. The Africans have been grouped according to country of origin and tribal affiliation. We have found no individual with an Ea1 gene and are unable to resolve the contradictory evidence for an ...
Kiloh L G - - 1976
A double-blind comparative trial of loxapine and trifluoperazine was carried out in 57 acute and chronic schizophrenic patients. In both groups of patients loxapine proved to be equivalent in its effects to trifluoperazine and there were suggestions it might be rather more effective in chronic patients. Side-effects were similar with ...
Small J G - - 1975
Lithium combined with major tranquilizers was administered to 22 hospitalized chronic schizophrenic patients with minimal neurotoxicity or other side effects. Moreover, 10 of the patients benefited significantly with lithium as compared to placebo in terms of blind psychiatric and nursing ratings and nonblind clinical judgments of outcome. These results contrast ...
Sakurai Y - - 1975
A dose of 50 mg of chlorpromazine (CPZ) was given to 6 untreated schizophrenic patients and 8 healthy volunteers at 7:00 a.m. before breakfast. Blood samples were taken 3, 6, 9 and 24 hrs after for the analyses of CPZ and its metabolites by gas chromatographic techniques. In the cases ...
Carpenter W T WT - - 1975
Keeping biochemical determinations and clinical judgements independent, the authors investigated three aspects of the transmethylation hypothesis. They found that 26 acutely schizophrenic patients were no more likely to have bufotenine or N,N-dimethyltryptamine present in urine or elevated serum indolethylamine N-methyltransferase activity than 10 normal control subjects. The authors conclude that ...
Landau S G - - 1975
A group pf 19 acute, medication-free schizophrenic patients was studied, using average-evoked responses (AERs) to four intensities of light. Comparison with age- and sex-matched normal controls and patients with bipolar affective disorders showed that schizophrenics had smaller AER amplitudes and either no increase or an actual decrease in amplitude with ...
Krishnamurthy S - - 1975
The response to lepromin and Kveim antigens was compared and studied in 15 leprosy patients who were tuberculin negative. Of the 11 lepromin positive tuberculoid patients, 4 were Kveim positive, 1 was equivocal, and the rest were negative. Of the four lepromin negative lepromatous patients, one gave a positive Kveim ...
Reilly F - - 1975
To study looseness of associations and other theoretically relevant variables of speech pathology, 51 acute psychiatric patients, including 26 schizophrenics, were studied at the acute phase of their disorder by means of a free verbalization interview. The results on these 51 patients during the acute period were: 1. There were ...
Moyano C Z - - 1975
Therapeutic efficacy and safety of loxapine succinate (LOX) and trifluoperazine hydrochloride were compared by means of a controlled, double-blind study involving 49 chronic schizophrenic inpatients. The data indicated that LOX in dosages ranging from 40 - 65 mg/day, (usually administered on a b.i.d. schedule) had demonstrable anti-psychotic activity in 14 ...
Domino E F - - 1975
Whole blood, plasma, or serum levels of various components were measured in fasting, drug-free control subjects and drug-free schizophrenic patients. Compared to normal controls, chronic schizophrenic patients showed increased alpha2-globulins and decreased plasma cholinesterase activity and ceruloplasmin activity, and acute schizophrenic patients showed decreased alpha2-globulins. Compared to chronic patients, acute ...
Jenkin R D - - 1975
The crude 5-year survival rate among children with Wilms' tumour increased from 54% for those diagnosed from 1960 to 1965 to 81% for the period 1966 to 1971. This resulted from an increased ability to cure metastatic disease and, to a lesser extent, to an increased ability to prevent relapse. ...
Smith G S - - 1975
Results of HL-A typing are presented in 82 patients with leprosy and 50 normal Filipinos from Cebu, and 144 normal Filipino immigrants from the Luzon area. Comparisons of HL-A antigen frequencies among the total patients and normals of Cebu showed no statistically significant differences; however, HL-A10 was increased in frequency ...
Bowers M B MB - - 1975
Lumbar cerebrospinal fluid (CSF) 5-hydroxyindoleacetic acid (5HIAA) following probenecid was negatively correlated with prognostic variables in a group of schizophrenic patients. Acute schizophrenic patients had lower CSF 5HIIA was negatively correlated with measured activity and rated agitation in a mixed group of schizophrenic patients. There is compelling evidence that LSD ...
Lim S D - - 1974
Study of the numbers of thymus-derived lymphocytes by the rosette assay (T-RFC) in patients with leprosy reveals that lower than normal numbers of T-RFC are regularly seen in those patients with the active lepromatous form of this disease. Essentially normal numbers of T-RFC were found in inactive lepromatous, borderline, and ...
McComas A J - - 1973
Forty-six patients have been studied after upper motor neurone lesions of cerebrovascular origin. The numbers of functioning motor units in extensor digitorum brevis muscles were reduced to approximately half between the second and sixth months after a hemiplegic episode. The surviving motor units tended to have slow twitches and appeared ...
Evans R J - - 1971
Nine patients with tabes dorsalis and one patient with diabetic autonomic neuropathy were subjected to hypoxia to test the integrity of their carotid chemoreceptors. Ventilation and pulse rate changes were monitored and compared with those of a group of normal subjects of comparable age and sex. Four patients had a ...
Salzano F M - - 1970
The distribution of the Australia antigen was investigated in 633 white and negroid healthy persons, 218 white and negroid leprosy patients, and 50 white leukaemia patients. The subjects were living at the time of the investigation in two southern Brazilian cities. Two of the patients with leukaemia showed the antigen, ...
Meltzer H - - 1968
Activity of creatine kinase and aldolase in serum increased in 14 of 16 patients with recent onset of a psychotic reaction, and in five of six patients treated with psychotomimetic drugs. There was either no increase of these enzymes or a slight increase in severely agitated (or depressed) non-psychotic hospitalized ...
CAHN C H - - 1963
Chlorprothixene, a thioxanthine derivative, claimed to have broad-spectrum antipsychotic properties, was compared with phenothiazine derivatives in the setting of a psychiatric admission service and aftercare clinic.In 32 female patients with paranoid symptoms, chlorprothixene in high dosage ranges (200 to 1200 mg. daily) was found to be as effective as similar ...
POLLIN W - - 1961
Large oral doses of individual amino acids were given three or four times daily for periods of 1 week to schizophrenic patients, some of whom were maintained on iproniazid. Marked alterations in behavior in some patients were associated with the administration of l-methionine and of l-tryptophan.
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