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Vyshedskiy Andrey - - 2012
Objective. The phenomenon of pendelluft was described over five decades ago. In patients with regional variations in resistance and elastance, gas moves at the beginning of inspiration out of some alveoli into others. Gas moves in the opposite direction at the end of inspiration. The objective of this study was ...
George Oommen K OK Department of Cardiology, Christian Medical College, Vellore, - - 2012
Erdheim Chester disease is a very rare histiocytic disorder characterised by tissue infiltration by lipid laden histiocytes. The most common presentation is bone pains typically involving the long bones. Over time almost 50% of the patients develop extraosseous involvement. The prognosis depends on the extent and distribution of the extraskeletal ...
Rougier Patrice R - - 2012
Purpose: In healthy adults, the beneficial effect of providing additional visual feedback (VFB) with a delay of either the center of pressure (CP) or the difference between CP movements and center of gravity (CP-CGv) movements was previously demonstrated and explained by their capacity to decrease their CP-CGv movements. The present ...
Hove Michael J - - 2012
Parkinson's disease (PD) and basal ganglia dysfunction impair movement timing, which leads to gait instability and falls. Parkinsonian gait consists of random, disconnected stride times--rather than the 1/f structure observed in healthy gait--and this randomness of stride times (low fractal scaling) predicts falling. Walking with fixed-tempo Rhythmic Auditory Stimulation (RAS) ...
Chen Jin-Bor - - 2012
The mitochondrial (mt) displacement loop (D-loop) is known to accumulate structural alterations and mutations. The aim of this study was to investigate the prevalence of single nucleotide polymorphisms (SNPs) within the D-loop among chronic dialysis patients and healthy controls. We enrolled 193 chronic dialysis patients and 704 healthy controls. SNPs ...
Brown Carlos V R - - 2012
Timely correction of coagulopathy in patients with traumatic brain injury (TBI) improves mortality. Recombinant, activated factor VII (VIIa) has been identified as an effective method to correct coagulopathy in patients with TBI. We performed a retrospective study (January 1, 2008-December 31, 2009) of all patients with TBI and coagulopathy (international ...
Uysal-Soyer Ozge - - 2012
Absence seizures are idiopathic epilepsies characterized by impairment of consciousness and generalized 2.5-4 Hz spike and slow wave discharges. This prospective study was performed to classify and define properties of subgroups of absence epilepsies. We included 31 patients, of whom seven were in the differential diagnosis group. On admission, absence ...
Dirven Linda - - 2012
To determine the prevalence of vertebral fractures (VFs) after 5 years of disease activity score (DAS)-steered treatment in patients with early rheumatoid arthritis (RA) and to investigate the association of VFs with disease activity, functional ability and bone mineral density (BMD) over time. Five-year radiographs of the spine of 275 ...
Graff Beata - - 2011
Syncope is a common presentation of sinus node dysfunction (SND). Some patients who receive a permanent pacemaker due to SND do not benefit from it and further diagnostic workup leads to the diagnosis of vasovagal syncope (VVS). The aim of the study was to identify electrophysiological criteria that can be ...
Yamawaki Kohei - - 2011
Background: The purpose of this study was to investigate whether patients with severe aortic stenosis (AS) and preserved ejection fraction (EF) have dyssynchrony and whether it improves after aortic valve replacement (AVR). Methods and Results: We studied 30 consecutive patients with severe AS and preserved EF undergoing AVR. For baseline ...
Jansen J O - - 2011
BACKGROUND: Rotational thromboelastometry (ROTEM(®)) relies on citrated blood samples, which are regarded as biologically stable for up to 4h after venepuncture. However, this recommendation is based on data from normal volunteers. The aim of this study was to evaluate possible temporal changes in the coagulability of blood samples from coagulopathic ...
Fragakis Nikolaos - - 2011
AimsIt is unknown as to whether the result of adenosine testing for the diagnosis of sinus node dysfunction (SND) depends on the clinical presentation. We investigated whether syncope or presyncope are associated with a more pronounced sinus nodal inhibition by adenosine in SND.Methods and resultsWe studied 46 patients with SND, ...
Wang Lian - - 2011
OBJECTIVE: Epileptic patients have a higher relapse risk when EEGs before the initiation of anti-epileptic drug (AED) withdrawal show epileptiform activity. The purpose of this study is to assess the characteristics of ambulatory EEGs before the decision to withdraw AEDs and to clarify potential influencing factors for abnormal EEGs. METHODS: ...
Fujiwara Hisako - - 2012
Magnetoencephalography (MEG) has been shown a useful diagnostic tool for presurgical evaluation of pediatric medically intractable partial epilepsy as MEG source localization has been shown to improve the likelihood of seizure onset zone (SOZ) sampling during subsequent evaluation with intracranial EEG (ICEEG). We investigated whether ictal MEG onset source localization ...
Denney Douglas R - - 2011
Studies of planning ability typically involve some version of the Tower of Hanoi or Tower of London (TOL). When these tests are administered to patients with multiple sclerosis (MS), the findings pertaining to planning "performance" have been conflicting. Possible reasons for failures to find deficits in planning performance among MS ...
Garg Ravin R Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, - - 2012
Fluorescence in situ hybridization can detect genomic abnormalities in up to 80% of cases and provides prognostic information on patients with chronic lymphocytic leukemia (CLL). Although 13q deletion as the sole abnormality has been found to confer a favorable prognosis, there are little data as to whether there is a ...
Sifri Ziad C - - 2011
Previous studies proposed that repeat head computed tomography (RHCT) is of no value in patients with a minimal head injury (MHI) and normal neurologic examination (NE). The goal of our study was to investigate the value of RHCT in patients with MHI with an abnormal NE. A retrospective chart review ...
Whitaker Graham T - - 2011
To evaluate the utility of fluorescence to assess penetration of quinolone ear drops (EDs) through tympanostomy tubes (TTs), the middle ear, eustachian tube, and into the oropharynx. Before-and-after trial. Academic, tertiary care hospital. Young children undergoing TT placement for otitis media and adolescents or adults undergoing repair of tympanic membrane ...
Brigo Francesco - - 2011
Rhythmic temporal theta bursts of drowsiness (RTTD), also known as "psychomotor variant", and subclinical rhythmic EEG discharge of adults (SREDA) are two EEG patterns of uncertain significance that occur without any correlation with epilepsy. Each of these patterns has been described to occur alone and in the literature there are ...
Rudzinski Leslie A - - 2011
The aim was to determine the electroencephalographic (or electroencephalogram [EEG]) findings predictive of functional outcome in a subset of patients with acute subdural hematoma (SDH) with epileptiform activity on their EEG. Twenty-four patients who underwent evacuation for acute or acute-on-chronic SDH and with epileptiform activity on EEG were identified retrospectively. ...
Hajsadeghi Shokoufeh - - 2011
The surface electrocardiogram (ECG) has been used as a useful method for detection of metabolic disturbances for a long time. However, it may be difficult to distinguish the exact disturbance when more than one metabolic abnormality exists in a patient simultaneously. Although, "classic" ECG characterizations of common electrolyte disturbances are ...
Davenport Ross - - 2011
To identify an appropriate diagnostic tool for the early diagnosis of acute traumatic coagulopathy and validate this modality through prediction of transfusion requirements in trauma hemorrhage. Prospective observational cohort study. Level 1 trauma center. Adult trauma patients who met the local criteria for full trauma team activation. Exclusion criteria included ...
Sulli Alberto - - 2011
OBJECTIVE.: Performing a medium-term longitudinal study to investigate the timing of transition through different patterns of nailfold microvascular damage in patients with systemic sclerosis (SSc). METHODS.: Thirty-eight SSc patients (median disease duration 12 months) showing at baseline the "Early" scleroderma-pattern of microangiopathy were followed-up by nailfold videocapillaroscopy (NVC) for a ...
Catarino Claudia B - - 2011
Video-electroencephalographic (EEG) ictal recordings play an important role in the pre-surgical evaluation of patients with medically refractory focal epilepsy. Paradoxical lateralization of the scalp EEG ictal onset patterns, consistently contralateral to the side of the proven epileptogenic lesion is rare but important to recognize, with possible implications on patient management. ...
Touma Zahi - - 2011
Objectives. To test whether non-fasting and fasting triglyceride (TG) levels differ in individual patients and whether TG (non-fasting and fasting) levels predict coronary artery disease (CAD) in lupus patients.Methods. Using predefined criteria for a patient's inclusion in this study, we identified the first available set of non-fasting and fasting TG ...
Schmitz-Hübsch Tanja - - 2011
BACKGROUND: The aim of the current study was to test the hypothesis of a fundamental impairment of vocal pacing in patients with spinocerebellar ataxia and Parkinson's disease. METHODS: Thirty-one patients with spinocerebellar ataxia, 42 patients with Parkinson's disease, and 43 healthy controls had to repeat a single syllable at a ...
O'Neill Ailbhe C - - 2011
Purpose:To assess the effect of a rapid needle-out patient-rollover time approach on the rate of pneumothorax after computed tomography (CT)-guided transthoracic needle biopsy of pulmonary nodules.Materials and Methods:The institutional review board approved the study, and all patients gave written informed consent. Between January 2008 and December 2009, percutaneous CT-guided lung ...
Lotfi A S - - 2011
Background: Peripheral arterial disease is a condition characterized by progressive arterial narrowing, which affects patients' quality of life. The purposes of this study were to (1) establish the feasibility of obtaining peripheral fractional flow reserve (pFFR) in the peripheral vascular circulation, (2) demonstrate an association between baseline pFFR and peak ...
Indic Premananda - - 2011
Temporal lobe epilepsy has been known to be associated with buildup of 4-7Hz activity preceded by attenuation near the seizure focus. Using a wavelet based algorithm, we recently showed that for the patients with temporal lobe epilepsy, frequency flow on the scalp EEG builds up to 5-12Hz range just prior ...
Romei M - - 2011
In the respiratory management of DMD patients it is still under debate what parameter should indicate the correct timing for institution of nocturnal non-invasive ventilation (NIV), in addition to forced vital capacity, which is generally considered as a prognostic marker of disease progression. The aim of this study was to ...
Sander K - - 2011
Objective: To examine the dynamics of intracranial venous flow patterns in patients with idiopathic intracranial hypertension (IIH). Methods: Nonrandomized controlled trial analyzing the difference in cerebral perfusion in 13 IIH patients and 12 healthy controls using contrast-enhanced duplex sonography. In patients, an additional 3D gradient echo magnetic resonance venography (MRV) ...
Su Rez Hamlet - - 2011
Abstract Conclusions: Rise time in the estimation of the gravitational vertical in the head tilt response (HTR) test is increased in patients with peripheral vestibular lesions and residual chronic dizziness. Objective: Assessment of the perception of the gravitational vertical in patients with peripheral vestibular lesions through the HTR. Methods: HTR ...
Ząbczyk Michał - - 2011
INTRODUCTION: Atrial fibrillation (AF) is associated with a prothrombotic state. OBJECTIVES: We evaluated associations of previous thromboembolic events with fibrinolytic parameters in patients with AF. PATIENTS AND METHODS: We studied 62 consecutive patients with permanent AF (27 men, 35 women, aged from 46 to 89 [median, 78] years). Patients receiving ...
Alesci S - - 2011
In patients with isolated prolonged in vitro bleeding time there is no standardised treatment concept. With this study we characterized the extent of bleeding symptoms. All diagnoses known to cause prolonged in vitro bleeding time (PFA-100) (epinephrine-cartridge >160 s, ADP-cartridge > 120 s) have been excluded, such as platelet function ...
Boonsinsukh Rumpa - - 2011
Objectives: To determine clinical characteristics that can be used to identify patients with stroke who can perform light touch contact with a cane during walking, and to determine whether these patients benefit from TC. Methods: A prediction and randomized experimental study was conducted of 62 patients (mean onset time, 43.8 ...
Lallemand Bénédicte - - 2012
Myotonic dystrophy (MD1) is a hereditary autosomal dominant disease with variable penetrance. Cardiac conduction disturbances are frequent and may be responsible for sudden death, but its progression was heretofore unknown. The aim of the study was to analyse the natural history of infrahissian conduction time in patients with a normal ...
Ulaş Umit Hıdır - - 2011
The aim of this study was to determine whether patients who faint earlier in the course of a tilt table study represent a separate population with a poorer prognosis or different pathophysiology. We analyzed differences across patients with different syncopal times on the tilt-table study to answer this question. This ...
Rombauts Luk - - 2011
OBJECTIVE: To explore whether the predictive value of antral follicle count (AFC) changes when measured at different times during the menstrual cycle. Antimüllerian hormone (AMH) and AFC are considered to be equally predictive of poor ovarian response; however, AMH is considered to have an advantage over AFC, because AMH concentrations ...
Trachani E - - 2011
Trachani E, Constantoyannis C, Sakellaropoulos GC, Stavrinou ML, Nikiforidis G, Chroni E. Heart rate variability in Parkinson's disease unaffected by deep brain stimulation. Acta Neurol Scand: DOI: 10.1111/j.1600-0404.2011.01605.x. © 2011 John Wiley & Sons A/S. Objectives -  Our aim was to investigate the impact of subthalamic nucleus deep brain stimulation (STN-DBS) ...
Chittiboina Prashant - - 2011
We analysed retrospectively the effect of missile trajectory on outcomes from civilian gunshot injury to the spine (GSIS) between 1994 and 2008. Most of the 98 patients were male (88.8%). A minority (8%) of patients had multiple column injuries and a bone or bullet fragment in the spinal canal (14%). ...
Passos Ana Morsch - - 2011
BACKGROUND: Pulmonary function, in HIV infected patients, has been associated with reduction in pulmonary ventilation parameters Methods: We conducted a prospective cross sectional study to evaluate the pulmonary function of AIDS patients cared for in the infectious diseases ambulatories. Maximal inspiratory (PImax) and expiratory (PEmax) pressures and spirometry were assessed. ...
De Gottardi Andrea - - 2011
To the Editor: In their review article, Tripodi and Mannucci (July 14 issue)(1) present data that suggest a procoagulant imbalance in cirrhosis. Resistance to anticoagulation that is mediated by thrombomodulin(2) and an increased relative risk of venous thromboembolism(3) indicate that patients with cirrhosis do not undergo anticoagulation because of their ...
- - 2011
To the Editor: In their review article, Tripodi and Mannucci (July 14 issue)(1) present data that suggest a procoagulant imbalance in cirrhosis. Resistance to anticoagulation that is mediated by thrombomodulin(2) and an increased relative risk of venous thromboembolism(3) indicate that patients with cirrhosis do not undergo anticoagulation because of their ...
Qi Xingshun - - 2011
To the Editor: In their review article, Tripodi and Mannucci (July 14 issue)(1) present data that suggest a procoagulant imbalance in cirrhosis. Resistance to anticoagulation that is mediated by thrombomodulin(2) and an increased relative risk of venous thromboembolism(3) indicate that patients with cirrhosis do not undergo anticoagulation because of their ...
Violi Francesco - - 2011
To the Editor: In their review article, Tripodi and Mannucci (July 14 issue)(1) present data that suggest a procoagulant imbalance in cirrhosis. Resistance to anticoagulation that is mediated by thrombomodulin(2) and an increased relative risk of venous thromboembolism(3) indicate that patients with cirrhosis do not undergo anticoagulation because of their ...
Schniepp Roman - - 2011
Temporal gait variability is a critical parameter in patients with balance problems. Increased magnitude of temporal gait variability corresponds to a higher risk of falls. The purpose of this study was to investigate the influence of walking speed on temporal stride-to-stride variability in patients with cerebellar and vestibular deficits. A ...
Belinchon Antonio - - 2011
Objective: To investigate the sequence and correlation of symptoms of Ménière's disease (MD) depending on their order of manifestation. Methods: Descriptive, longitudinal study of the symptoms in 237 tertiary hospital patients who had been diagnosed with definite MD according to the criteria of the American Academy of Otolaryngology. Patients were ...
Thomalla Götz G Klinik und Poliklinik für Neurologie, Kopf- und Neurozentrum, Universitätsklinikum Hamburg-Eppendorf, Hamburg, Germany. - - 2011
Many patients with stroke are precluded from thrombolysis treatment because the time from onset of their symptoms is unknown. We aimed to test whether a mismatch in visibility of an acute ischaemic lesion between diffusion-weighted MRI (DWI) and fluid-attenuated inversion recovery (FLAIR) MRI (DWI-FLAIR mismatch) can be used to detect ...
Beynon C - - 2011
Parenchymal hemorrhage is one of the most feared risks of stereotactic brain biopsies potentially resulting in neurological deficits or even a fatal outcome. Patients with disorders of the coagulation system are at particular risk, so identifying these is one of the main tasks prior to surgery. Some patients may have ...
Moon Su-Jin - - 2011
OBJECTIVE: Since chronic kidney disease (CKD) is closely associated with cardiovascular disease and mortality as well as endstage renal disease, prediction of progressive CKD is a clinically important issue. We investigated the independent risk factors for the development of CKD in patients with lupus nephritis (LN). METHODS: The cohort included ...
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