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Petraitis, Sigitas
Objective. To evaluate and analyse the correlation between cervical cytology and postconization histology. Materials and Methods. 473 female patients operated on (diathermo- conization) at IOVU were retrospectively analysed. All patients had at least one preoperative cervical cytology evaluated according to the Bethesda system, and all postoperative specimens were histologically evaluated. ...
Tanaka Yoshiya Y The First Department of Internal Medicine, School of Medicine, University of Occupational and Environmental Health Japan , Kitakyushu , - - 2014
Objective. To investigate the efficacy and safety of abatacept for treating patients with rheumatoid arthritis (RA) in routine clinical practice. Methods. We performed a retrospective study of 137 RA patients who were treated with abatacept for 24 weeks between October 2010 and June 2011 at four rheumatology centers in Japan. ...
Ciubotariu Elena E From the Division of Rheumatology, University Hospital Sacré Coeur de Montréal, Montréal, Canada; Division of Rheumatology, University Hospital of Geneva; and Division of Clinical Epidemiology, University Hospital of Geneva, Geneva, Switzerland. E. Ciubotariu is supported by research grants from Montréal University and AMRQ (Association des Médecins Rhumatologues du Québec). A. Finckh is supported by a research grant from the Geneva University and the Swiss National Science Foundation (Grant No. 3200B0-120639). C. Gabay is supported by the Swiss National Science Foundation (Grant No. 310030-135195). E. Ciubotariu, MD, MSc, Division of Rheumatology, University Hospital Sacré Coeur of Montréal; C. Gabay, MD, PhD, Professor, Division of Rheumatology, University Hospital of Geneva; A. Finckh, MD, PhD, Adjoint Professor Division of Rheumatology; Division of Clinical Epidemiology, University Hospital of Geneva. Address correspondence to Drs. Ciubotariu and Finckh, Division of Rheumatology, Department of Internal Medicine, University Hospital of Geneva, 26 Av. Beau-Sejour, 1211 Geneva 14. E-mail: ileana.ciubotariu@gmail.com, axel.finckh@hcuge.ch. Accepted for publication February 20, - - 2014
Randomized controlled studies have demonstrated protective advantages of biologic therapies over the synthetic disease-modifying antirheumatic drugs (DMARD) in slowing joint damage progression in patients with rheumatoid arthritis (RA). This effect appears to be largely independent of the clinical disease control. We measured the rate of radiographic progression in patients with ...
Toor Muhammad R MR Lenox Hill Hospital, 100 East 77th Street, New York, NY, 10075, USA, - - 2014
A variety of therapeutic modalities are available to alter the abnormalities seen in patients with chronic kidney disease (CKD). A comprehensive plan can now be developed to slow the progression of CKD. Two clinical cases of delay in the need for renal replacement therapy are described. This delay was achieved ...
Locatelli Francesco F Alessandro Manzoni Hospital, Department of Nephrology Dialysis , Via dell'Eremo 9, 23900 Lecco , Italy +39 0341 489850 ; +39 0341 489860 ; - - 2014
Introduction: Hyperphosphatemia is common in the late stages of chronic kidney disease (CKD) and is associated with elevated parathormone levels, abnormal bone mineralization, extraosseous calcification and increased risk of cardiovascular events and death. Several classes of oral phosphate binders are available to help control phosphorus levels. Although effective at lowering ...
Takahashi Shinji S Department of Orthopaedic Surgery, Osaka City University Medical School , Osaka , - - 2014
Objectives. Cervical spine instability (CSI) is commonly involved in patients with rheumatoid arthritis (RA). Although the treatment for RA has dramatically changed due to methotrexate and biologics, it is unclear whether this change contributes to the prevalence of CSI or not. Our objectives were to update the current prevalence of ...
Farkas Klaudia K Klaudia Farkas, Éva Pallagi-Kunstár, Anita Bálint, Ferenc Nagy, Zoltán Szepes, Noémi Vass, Tibor Wittmann, Tamás Molnár, First Department of Medicine, University of Szeged, H6720 Szeged, - - 2014
To assess the endoscopic activity before and after a one-year period of biological therapy and to evaluate the frequency of relapses and need for retreatment after stopping the biologicals in patients with Crohn's disease (CD) and ulcerative colitis (UC). The data from 41 patients with CD and 22 patients with ...
Sauvée Mathilde M Service de Neurologie, Centre Hospitalier Universitaire, Nancy, - - 2014
Background: Cerebrospinal fluid (CSF) biomarkers have recently been included in the criteria for the diagnosis of Alzheimer's disease (AD). Since interpretation of CSF profile requires the combination of three parameters, biological data are not always conclusive and isolated elevation of phosphorylated tau (P-tau) or reduction of amyloid-β (Aβ)42 alone can ...
Poncin M - - 2014
Our goals were to assess the prevalence of biological and tissue remission in routine practice in Crohn's disease, and to evaluate the correlation between biological or tissue remission and clinical or demographic characteristics as well as their impact on disease outcome. We performed a retrospective monocenter study. Biological remission was ...
Goodman Susan M SM Division of Rheumatology, Weill Cornell Medical College, New York, NY 10065 USA ; Division of Rheumatology, Hospital for Special Surgery, 535 East 70th St, New York, NY 10021 - - 2014
Preoperative expectations of total knee arthroplasty (TKA) correlate with postsurgical satisfaction, and are linked to outcomes. Rheumatoid arthritis (RA), and other chronic diseases, may lower expectations, although new biologic medications have greatly enhanced patients' quality of life. The purpose of this study is to compare preoperative expectations of RA to ...
Kaur Navjot N 0000-0002-5179-0773 Department of Pharmacology, Postgraduate Institute of Medical Education & Research, Chandigarh 160012, - - 2014
Background. Terminalia arjuna is a popular Indian medicinal plant with its bark been used for over centuries as cardiotonic. The bark has been found to contain several bioactive compounds including saponins and flavonoids. A number of experimental and clinical studies have been conducted to explore therapeutic potential of Terminalia arjuna ...
Di Franco Manuela M Reumatologia, Dipartimento di Medicina Interna e Specialità Mediche, Sapienza Università di Roma, Rome, - - 2014
Rheumatoid arthritis (RA) management has greatly improved with the development of biologic disease modifying antirheumatic drugs, but a proportion of patients do not improve despite the biologic drugs currently available. We need new biologic agents with novel mechanisms of action for the treatment of refractory patients. Recent evidence has shown ...
Jedynak Waldemar W Department of Diagnostic Imaging, Hospital of the West, Jan Paul II, Grodzisk Mazowiecki, - - 2014
Summary Though the etiology of multiple sclerosis remains unknown, the widely accepted explanation is that it has an autoimmune inflammatory background. In 2006 Paolo Zamboni renewed the somewhat forgotten vascular theory of the pathogenesis of multiple sclerosis, proposing the new entity of 'chronic cerebrospinal venous insufficiency'. As a result of ...
Santiago Jose A JA Department of Cellular and Molecular Pharmacology, The Chicago Medical School, Rosalind Franklin University of Medicine and Science, North Chicago, Illinois, - - 2013
Diagnosis of progressive supranuclear palsy (PSP) remains challenging because of the clinical overlap with Parkinson's disease (PD). To date, disease-specific biomarkers have yet to be identified. In the absence of reliable biomarkers, we used an integrated network approach to identify genes and related biological pathways associated with PSP. We tested ...
Athanasiadis Theodore - - 2013
Cough lasting more than 8 weeks is a common presenting complaint to the otolaryngologist. Historically, chronic cough has been attributed to post-nasal drip, laryngopharyngeal reflux and cough-variant asthma. This study reviews chronic cough from the viewpoint of an otolaryngologist. More recent studies suggest the influence of laryngeal neuropathy and its ...
Andersen Lars W LW Research Center for Emergency Medicine, Aarhus University Hospital, Aarhus, Denmark; Department of Emergency Medicine, Beth Israel Deaconess Medical Center, Boston, - - 2013
Lactate levels are commonly evaluated in acutely ill patients. Although most often used in the context of evaluating shock, lactate levels can be elevated for many reasons. While tissue hypoperfusion may be the most common cause of elevation, many other etiologies or contributing factors exist. Clinicians need to be aware ...
Halachmi-Eyal Orly - - 2013
We aim to give a systematic approach on how to assess the cause of a patient's abnormal head posture (AHP). Over the decades, many important clinical observers and teachers have described diagnostic techniques for patients with AHP. Recently, Wong has added a new set of office-based diagnostic criteria that expand ...
Smith Ross K - - 2013
The etiology of primary chronic venous insufficiency is poorly understood. This systematic review aimed to summarize published evidence assessing the association of circulating markers with primary chronic venous insufficiency. A search was undertaken through the PubMed database using the terms "venous insufficiency" and "biological marker" or "plasma" or "serum". Search ...
Konstantinos Katsoulis K - - 2013
In recent years special interest has been expressed for the contribution of small airways in the pathophysiology, clinical manifestations and treatment of asthma and COPD. Small airways contribute little to the total respiratory resistance so that extensive damage of small airways may occur before the appearance of any symptoms, and ...
Abdulqawi Rayid R Respiratory and Allergy Centre, The University of Manchester, University Hospital of South Manchester, Manhester, - - 2013
Gastro-oesophageal reflux, either singly or in association with postnasal drip and/or asthma is considered to be a cause of chronic cough. The amount and nature of gastro-oesophageal reflux however is often normal with acid suppression having very little, if any therapeutic effect in these patients. This review examines the challenges ...
Garcia Raul I - - 2013
ARTICLE TITLE AND BIBLIOGRAPHIC INFORMATION: A nationwide population-based study on the association between chronic periodontitis and erectile dysfunction. Keller JJ, Chung S-D, Lin H-C. J Clin Periodontol 2012;39:507-12. REVIEWER: Raul I. Garcia, DMD, MMedSc PURPOSE/QUESTION: To explore the association between chronic periodontitis and erectile dysfunction SOURCE OF FUNDING: Authors received ...
Kolyva Christina C Department of Medical Physics and Bioengineering, University College London, London, - - 2013
Spontaneous oscillations in cerebral haemodynamics studied with near-infrared spectroscopy (NIRS), become impaired in several pathological conditions. We assessed the spectral characteristics of these oscillations in 20 patients with falciparum malaria admitted to Ispat General Hospital, Rourkela, India. Monitoring included continuous frontal lobe NIRS recordings within 24 h of admission (Day ...
Alvarez-Sabín José J Neurovascular Unit, Department of Neurology, Universitat Autónoma de Barcelona, 119-129 Passeig de la Vall d'Hebron, Barcelona 08035, Spain. - - 2013
Advances in acute stroke therapy resulting from thrombolytic treatment, endovascular procedures, and stroke units have improved significantly stroke survival and prognosis; however, for the large majority of patients lacking access to advanced therapies stroke mortality and residual morbidity remain high and many patients become incapacitated by motor and cognitive deficits, ...
Schaeverbeke Thierry - - 2012
The major strides accomplished in elucidating the pathophysiology of rheumatoid arthritis (RA) have translated into therapeutic breakthroughs in clinical practice. However, currently available treatments work only for as long as they are taken. The development of curative treatments will probably require a better understanding of the earliest phases of RA ...
Ducher Michel - - 2012
Biological diagnostic criteria for diagnosing aldosterone-producing adenoma (APA) are not well-established. The aim of the study was to establish the best biological predictors of APA. A prospective register was implemented in 17 secondary or tertiary hypertension centres. The inclusion criterion was one of the following: onset of hypertension before 40 ...
Oʼsullivan Michael D - - 2012
PURPOSE OF REVIEW: It is 20 years since the 10 Warning Signs of primary immunodeficiency (PID) were first published and with over 180 PIDs now identified it is timely to evaluate their effectiveness, given the broadening clinical spectrum of PID. RECENT FINDINGS: Two recent studies have sought to define the ...
Khan Omar - - 2012
ABSTRACT: We report 6 patients with an established diagnosis of primary Sjögren syndrome who developed severe rheumatoid arthritis (RA) requiring oral disease-modifying antirheumatic drug with or without biologic therapy. Rheumatoid arthritis was diagnosed between 14 months and 17 years following initial sicca symptoms. Five patients were female. Two thirds were ...
Hakim Antoine M - - 2012
Studies with tissue plasminogen activator (t-PA) published in 1995 showed significant improvement in stroke outcome if the drug was administered within 3 hours from stroke onset. Several recent reports, however, show that less than 5% of stroke patients may be receiving t-PA in many parts of North America. This paper ...
Pinto Susana - - 2012
Some patients with amyotrophic lateral sclerosis (ALS) die suddenly despite normal nocturnal pulse oximetry (NPO), possibly due to dysautonomia. Forty-four ALS patients without other medical conditions were studied. Heart rate variability was assessed through finger oximetry. The heart rate coefficient of variation (HR CV) was evaluated during nocturnal sleep. All ...
Joo Sunyoung - - 2012
: Although the uninvolved foot in patients with hemiplegia has been thought to be normal, we frequently observed valgus deformity of the uninvolved foot among those patients. The purpose of this study was to evaluate by dynamic pedobarograph the prevalence and pattern of foot deformity in the uninvolved limb among ...
Viscardi Andrea - - 2012
: Dynamic transperineal ultrasound has been used in women for the noninvasive investigation of functional disorders of the posterior pelvic floor, but its use in men has been limited by technical difficulties related to the consistency of the male perineum. : The aim of this study was to explore the ...
Zerbib Frank - - 2012
Approximately 20-30% of patients with gastro-esophageal reflux symptoms report inadequate symptom relief while on proton-pump inhibitor therapy. The mechanisms involved are failure of the antireflux barrier (transient lower esophageal sphincter relaxations), high proximal extent of the refluxate, esophageal hypersensitivity and impaired mucosal integrity. Persisting acid or nonacid reflux can be ...
Hamilton Joanne M - - 2012
The current study explored the value of visuospatial findings for predicting the occurrence of visual hallucinations (VH) in a sample of patients with dementia with Lewy bodies (DLB) compared with patients with Alzheimer disease (AD). PARTICIPANTS/MEASUREMENTS: Retrospective analysis of 55 autopsy-confirmed DLB and 55 demographically similar, autopsy-confirmed AD cases determined ...
Küpers Elselien M - - 2012
Context:Adrenal venous sampling is recommended to assess whether aldosterone hypersecretion is lateralized in patients with primary aldosteronism. However, this procedure is invasive, poorly standardized, and not widely available.Objective:Our goal was to identify patients' characteristics that can predict unilateral aldosterone hypersecretion in some patients who could hence bypass adrenal venous sampling ...
Wu Li Na - - 2012
Purpose: To investigate the incidence and relative factors of Terson's syndrome (TS) in patients with subarachnoid hemorrhage (SAH) in China. Materials and Methods: A case series study was conducted from November 2009 to June 2010 on 155 patients (310 eyes) with aneurysmal and traumatic SAH. A thorough, direct funduscopic examination ...
Girasis Chrysafios - - 2012
AIMS: The maintenance of sinus rhythm is crucial for the functional capacity of patients with hypertrophic cardiomyopathy (HCM). Using a multimodality approach, we attempted to identify potential predictors of paroxysmal atrial fibrillation (PAF) in HCM patients. METHODS AND RESULTS: Thirty HCM patients (17 males, mean age 57.9 ± 13.6) with ...
Maury Philippe - - 2012
Background: T-wave alternans (TWA) is an accepted marker of risk for malignant ventricular arrhythmias, for which prognosis value has been established in different populations. Short QT syndrome (SQTS) is a very rare primary electrical disease carrying the risk of ventricular fibrillation. TWA in SQTS has not been evaluated yet. Methods: ...
Kauer Floris - - 2012
AIMS: This study sought to investigate regional left ventricular (LV) rotation in patients with hypertrophic cardiomyopathy (HCM). METHODS AND RESULTS: The study comprised 44 patients with HCM with a typical reverse septal curvature (age 40 ± 14 years, 33 men) and 44 healthy volunteers (age 39 ± 14 years, 32 ...
Masuda Toshiro - - 2012
BACKGROUND/PURPOSE: The indications for hepatic resection for hepatocellular carcinoma (HCC) patients with total bilirubin (T-Bil) equal to or higher than 1.2 mg/dl remain controversial. The aim of this study was to investigate the safety of hepatic resection for HCC patients who showed high T-Bil (≥1.2 mg/dl) with low direct bilirubin (D-Bil ≤ 0.5 mg/dl). METHODS: ...
Fraioli Mario Francesco - - 2012
Radiosurgery (RS) and hypofractionated stereotactic radiotherapy (HSRT) were performed in 23 and 22 patients respectively for the treatment of trigeminal neuralgia. RS and HSRT were performed with a dedicated linear accelerator (LINAC): an invasive frame (for RS) or a relocatable stereotactic frame fitted with a thermoplastic mask and bite blocks ...
Angst Patrícia Daniela Melchiors - - 2012
AIM: This cross-sectional study evaluated periodontal status in patients with leukaemia and its correlation with haematological parameters. METHODS: Patients with different types of leukaemia and minimum age of 14 years were eligible. Calibrated examiners assessed Seymour index (SI), plaque index (PlI), gingival index (GI), probing depth (PD), bleeding on probing (BOP) ...
Martínez Fernández G - - 2012
BACKGROUND: To calculate Kt/V, volume (V) is usually obtained by Watson formula, but bioimpedance spectroscopy (BIS) is a simple and applicable technique to determinate V, along with other hydration and nutrition parameters, in peritoneal dialysis (PD) patients. Dialysis efficacy can also be measured with Kt, but no experience exists in ...
Akyildiz Serdar - - 2012
Objectives: To identify the effects of laryngopharyngeal reflux (LPR)-related laryngeal findings on objective voice parameters. Methods: Two hundred and thirty patients clinically diagnosed as having LPR and 48 healthy controls were included. The reflux finding score was determined for each subject via videolaryngoscopy. The acoustic parameters evaluated were jitter, shimmer, ...
Long Margaret E - - 2012
OBJECTIVE: This study aimed to estimate dysplasia rate in histologically evaluated endocervical polyps and to compare histological and clinical characteristics of dysplastic (D) polyps with those displaying representative benign changes. MATERIALS AND METHODS: Endocervical polyps removed at Mayo Clinic from January 1994 to December 2010 were categorized as polyp without ...
Dilorenzo Michael P - - 2012
PURPOSE: Ablation of anteroseptal accessory pathways have historically been associated with lower success rates and a higher risk of AV nodal injury due to close proximity to the compact AV node. We describe the technique of ablation of anteroseptal APs via the right internal jugular vein (RIJV). METHODS: A retrospective ...
Aglan Mona S - - 2012
Osteogenesis imperfecta (OI) is a heritable skeletal disorder with bone fragility and often short stature. This study provides anthropometric measurements in Egyptian children with OI and determine variability among OI types classified according to Sillence et al. [Sillence et al. (1979); J Med Genet 16:101-116]. The study included 124 patients ...
Singh Jittendra K - - 2012
INTRODUCTION: Studies suggest that ethnicity and racial factors has an important role in the variation in epidemiology of stroke. The present study was conducted to assess the subtypes, risk factors, and outcome of stroke in the tribal community of Jharkhand state and to compare it with that in the non-tribals ...
Kızıltan Meral E - - 2012
BACKGROUND AND AIM: Orthostatic tremor is a high frequency tremor predominantly on calf muscles during standing. Brainstem is the most probable generator in the pathogenesis since it comprises bilaterally projecting centers regulating stance or tone. We aimed to investigate the functional role of brainstem through the evaluation of acoustic startle ...
Weigt J - - 2012
Until now, it is uncertain if the so-called pH-only reflux episodes that consist of a pH drop without evidence of retrograde bolus movement in multichannel intraluminal impedance (MII) represent reflux episodes or artifacts. Hiatal hernia (HH) may allow reflux of small volumes to occur that can be detected by pH-metry ...
Wang Huay-Min - - 2012
  To evaluate the liver stiffness measurement (LSM) using transient elastography (TE) to predict the risk of esophageal varices (EVs) in Chinese patients.   In total, 46 patients with suspicious or proven liver cirrhosis underwent TE and liver biopsy. All participants were endoscopically screened for the presence of EVs and ...
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