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Results 201 - 250 of 1563
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Ni Ling - - 2012
Little is known about how spontaneous brain activity progresses from non-hepatic encephalopathy (non-HE) to minimal HE (MHE). The purpose of this study was to evaluate the evolution pattern of spontaneous brain activities in cirrhotic patients using resting-state fMRI with a regional homogeneity (ReHo) method. Resting-state fMRI data were acquired in ...
Suzuki Bellucci Carlos H - - 2012
Combined pelvic floor electromyography (EMG) and videocystourethrography (VCUG) during urodynamic investigation are the most acceptable and widely agreed methods for diagnosing detrusor external sphincter dyssynergia (DESD). Theoretically, external urethral sphincter pressure (EUSP) measurement would provide enough information for the diagnosis of DESD and could simplify the urodynamic investigation replacing combined ...
Van Remoortel Hans - - 2012
Reduced physical activity is an important feature of Chronic Obstructive Pulmonary Disease (COPD). Various activity monitors are available but their validity is poorly established. The aim was to evaluate the validity of six monitors in patients with COPD. We hypothesized triaxial monitors to be more valid compared to uniaxial monitors. ...
Shin Soojeong - - 2012
The pronator drift test is widely used to detect mild arm weakness. We developed an application that runs on a handheld device to objectify the pronator drift test and investigated its feasibility in stroke patients. The iPronator application, which uses the built-in accelerometer in handheld devices, was developed. We enrolled ...
Qi Rongfeng - - 2012
Live failure can cause brain edema and aberrant brain function in cirrhotic patients. In particular, decreased functional connectivity within the brain default-mode network (DMN) has been recently reported in overt hepatic encephalopathy (HE) patients. However, so far, little is known about the connectivity among the DMN in the minimal HE ...
Schuster Corina - - 2012
A combination of physical practice and motor imagery (MI) can improve motor function. It is essential to assess MI vividness in patients with sensorimotor impairments before implementing MI interventions. The study's aims were to translate the Canadian Kinaesthetic and Visual Imagery Questionnaire (KVIQ) and the French Imaprax, and to examine ...
Lungu Ovidiu - - 2012
Corpus callosum (CC) is essential in providing the integration of information related to perception and action within a subcortico-cortical network, thus supporting the generation of a unified experience about and reaction to changes in the environment. Its role in schizophrenia is yet to be fully elucidated, but there is accumulating ...
Hirata Eunice Sizue ES Faculdade de Ciências Médicas, Universidade de Campinas (Unicamp), Brazil. - - 2012
This study had the purpose of studying gastric emptying in patients with chronic renal failure. Thirty patients with chronic renal failure were studied, 16 in conservative clinical treatment and 14 in hemodialysis for over six months. The control group (CTL) was composed of 18 asymptomatic volunteers. The method of gastric ...
Lin Keh-Chung KC School of Occupational Therapy, College of Medicine, National Taiwan University, Taipei, - - 2012
To validate the dimensionality, hierarchical properties, and reliability of the Frenchay Activities Index. Self-report survey of patients with stroke. A total of 127 patients provided 254 observations before and after treatments. Multidimensional Rasch model was conducted. The 2-factor model showed the significantly smallest deviance and fitted the data best among ...
Perricone Carlo - - 2011
Objective. Musculoskeletal US can be useful in monitoring RA. It can be time-consuming and there is no consensus in defining the joints to evaluate. We assessed the validity, sensitivity to change and feasibility of a reduced 6-joint US score in patients with RA starting therapy with an anti-TNF agent.Methods. A ...
Battista Natalia - - 2011
The endocannabinoid system has been extensively investigated in experimental colitis and inflammatory bowel disease, but not in celiac disease, where only a single study showed increased levels of the major endocannabinoid anandamide in the atrophic mucosa. On this basis, we aimed to investigate anandamide metabolism in celiac disease by analyzing ...
Ujhelyi Bernadett - - 2011
Background: Secretion of cytokines and display of cytokine receptors have been reported in the orbital connective tissue in Graves' orbitopathy (GO). Lacrimal glands are putative autoimmune targets, and changes in tear film and ocular surface have also been described. Our aim was to characterize the cytokine profile of tears in ...
White Deborah L - - 2012
The functional activity of the organic cation transporter 1 (OCT-1) protein (OCT-1 activity) is an excellent predictor of molecular response and progression-free survival in patients with newly diagnosed chronic phase chronic myeloid leukemia treated with imatinib as front-line therapy. In this study the predictive value of OCT-1 activity in patients ...
Cheung Irene Y - - 2012
Adjuvant therapy using anti-GD2 monoclonal antibody and granulocyte-macrophage colony-stimulating factor (GM-CSF) has shown treatment success for patients with high-risk neuroblastoma (NB). Although there is ample evidence on how the antibody targets NB, in vivo contribution by GM-CSF remains unclear. This report investigates granulocyte activation and its correlation with treatment outcome. ...
Bayrak Ahmet - - 2012
Paraoxonase-1 (PON1) is an antioxidant enzyme located in high density lipoprotein (HDL). PON1 was defined as a protective factor against atherosclerosis. The aim of this study was to investigate the possible relationship between serum paraoxonase (PONase), homocysteine thiolactonase (HTase) activities and PON1 Q192R polymorphism, and the extent and severity of ...
Marconi Sara - - 2011
BACKGROUND: Neurophysiological investigations disclosed spinal cord hyperexcitability in primary restless legs syndrome (p-RLS). Uremic RLS (u-RLS) is the most common secondary form, but its pathophysiological mechanisms remain unsettled. Aim of this study was to explore spinal cord excitability by evaluating group I nonreciprocal (Ib) inhibition in u-RLS patients in comparison ...
Battisti Vanessa - - 2011
Prostate cancer (PCa) is the sixth most common type of cancer worldwide. Cholinesterase is well known as having non-cholinergic functions such as cellular proliferation and differentiation, suggesting a possible influence of cholinesterase in tumorogenesis. Thus, the aim of this study was to investigate the whole blood acetylcholinesterase (AChE) and plasma ...
Koessler Juergen - - 2011
Recently, the INNOVANCE® PFA P2Y (P2Y) cartridge of the PFA-100® system (Siemens Healthcare Diagnostics, Marburg, Germany) has been developed for the monitoring of adenosine diphosphate (ADP) P2Y(12) receptor inhibition in patients under dual antiplatelet therapy. The aim of this study was to evaluate the influence of pre-existing defects in primary ...
Garfield Benjamin E - - 2012
Quantification of daily physical activity is of clinical interest in chronic obstructive pulmonary disease (COPD). Objective measures using activity monitors may take several days to obtain reliable results. The aim of our study was to evaluate the Stanford Seven-Day Physical Activity Recall questionnaire (PAR) against the SenseWear armband (SWA) and ...
Del Brutto Oscar H - - 2011
OBJECTIVE: To confirm recent evidence suggesting a change in the pattern of disease expression of neurocysticercosis, manifested by a decreasing number of severe and recent infections. METHODS: Retrospective cohort of 246 neurocysticercosis patients residing in Guayaquil, evaluated over 20 years (1990 to 2009). Eighty-seven patients were seen from 1990 to ...
Pucciani F - - 2011
BACKGROUND: The aim of the study was to evaluate the clinical usefulness of anorectal manometry (AM) in patients affected by obstructed defecation (OD). METHODS: Between January 2007 and December 2010, 379 patients (287 women and 92 men) affected by OD were evaluated. After a preliminary clinical evaluation, defecography and AM ...
Yamazaki M - - 2011
BACKGROUND AND PURPOSE:3D-FLAIR imaging 24 hours after intratympanic gadolinium injection (IT-method) or 4 hours after IV injection (IV-method) has been used to visualize the endolymphatic hydrops in Ménière disease. The purpose of this study was to compare the degree of perilymph enhancement with the 2 methods and the perilymph contrast-effect ...
Subash Mala - - 2011
AimTo describe the clinical features of a case series of patients with unilateral vitelliform maculopathy and the results of screening BEST1 and PRPH2 for disease-causing mutations.Design/MethodsThis was a retrospective case series study of six patients ascertained over a 2-year period. Ophthalmological examination, fundus photography, autofluorescence imaging, optical coherence tomography and ...
Ricchi Paolo - - 2011
In thalassemia intermedia (TI), the increase in bone marrow hemopoietic activity frequently leads to extramedullary erythropoeisis (EMH), but its relationship with the soluble form of transferrin receptor (sTfR) which fully reflects the marrow erythropoietic activity, has not yet been explored. From January 2007 to December 2010, all TI patients attending ...
Relan Anurag - - 2011
Background: Recombinant human C1-inhibitor (rhC1INH; Ruconest®) has been developed for treatment of acute angioedema attacks in patients with hereditary angioedema (HAE) due to heterozygous deficiency of C1INH. Previous reports suggest that administration of plasma-derived C1INH products may be associated with an increased risk for thromboembolic complications. Objectives: Our aim is ...
Delgado Pilar - - 2011
Background: Lipoprotein-associated phospholipase A(2) (Lp-PLA(2)) has emerged as a novel biomarker in cardiovascular diseases due to its ability to predict stroke in population-based studies. We aimed to investigate Lp-PLA(2) levels in transient ischemic attack (TIA) patients and to study their relationship with stroke recurrence. Methods: Lp-PLA(2) mass and activity were ...
Hindorf Ulf - - 2011
BACKGROUND AND AIMS: A pre-treatment determination of the thiopurine S-methyltransferase (TPMT) genotype or phenotype can identify patients at risk of developing severe adverse reactions from thiopurine treatment. The risk of misclassifying a patient might be dependent on the method used. The aim of this study was to investigate the concordance ...
De Franco Antonio - - 2011
Purpose:To quantitatively assess microvascular activation in the thickened ileal walls of patients with Crohn disease (CD) by using contrast-enhanced ultrasonography (US) and evaluate its correlation with widely used indexes of CD activity.Materials and Methods:This prospective study was approved by the ethics committee, and written informed consent was obtained from all ...
Therese Krarup - - 2011
Many clinical features are common for patients with Type 2 Diabetes Mellitus (T2DM) and Cushing's Syndrome (CS) such as central obesity, hypertension and dyslipidaemia. Patients with CS often have T2DM. Since T2DM is much more frequent than CS it is possible that some patients with T2DM have increased production of ...
Yilmaz Guldal - - 2011
Abstract Introduction: Hepatoportal sclerosis (HPS) is a syndrome of obscure etiology and is one of the causes of non-cirrhotic portal hypertension (PH). We aimed to investigate this heterogeneous group of patients whose presentation showed cholestatic features, histopathologically. Methods: Between 1999 and 2009, 12 children diagnosed with HPS were retrospectively evaluated. ...
Rey Jean-Francois - - 2011
BACKGROUND: Passive video capsule endoscopy is the criterion standard for small-bowel exploration but cannot be used for the large gastric cavity. We report the first blinded comparative clinical trial in humans comparing a magnetically guided capsule endoscope (MGCE) and a conventional high-definition gastroscope. OBJECTIVE: To assess the potential of gastric ...
Calver Leonie - - 2011
A 27-year-old male who had been on methadone therapy for 6 months was investigated with a 12-lead digital holter because of a prolonged QT on a standard 12-lead electrocardiogram (ECG). The patient had 24-hour holter recording on and off methadone therapy and multiple digitized 12-lead ECG data were captured for ...
Mabrouk Hajer - - 2011
Butyrylcholinesterase (BChE) is an enzyme that has been investigated for its putative role in neurodegenerative and neuropsychiatric disorders. The aim of our work was to study BChE activity variations in schizophrenic patients and to investigate the involvement of this enzyme in schizophrenia and the importance of determining its activity in ...
Cannon Grant W - - 2011
The Veterans Affairs (VA) Rheumatoid Arthritis (VARA) registry and the VA Pharmacy Benefits Management database were linked to determine the association of methotrexate (MTX) adherence with rheumatoid arthritis (RA) disease activity. For each patient, the medication possession ratio (MPR) was calculated for the first episode of MTX exposure of a ...
Wong S W - - 2011
There is mounting evidence demonstrating the importance of adequate physical activity to promote better well-being among hemodialysis patients. Available data pertaining to the levels of physical activity and its determinants among hemodialysis patients is, however, scarce in Malaysia. The objectives of this study are hence to determine the levels of ...
Alanbay Ibrahim - - 2011
Objective: To study the levels of chitotriosidase activity in the peritoneal fluid and the plasma of patients with severe endometriosis and control subjects. Materials and methods: Twenty-five women with laparoscopically and histopathologically confirmed endometriosis (study group) and 27 control patients who had undergone laparoscopic surgery were included. Peritoneal fluid and ...
Itaquy Roberta Baldino - - 2011
The aim of this case study was to verify the occurrence of dysphagia in acute ischemic stroke within 48 hours after the onset of the first symptoms, in order to establish a possible relationship between the level of neurologic impairment and the severity degree of dysphagia. After emergency hospital admission, ...
Shavit Linda - - 2011
Introduction: The prevalence of heparin-induced antibodies (HIA) varies widely among reported series, but is generally higher in cardiac surgery than hemodialysis patients. This study was designed to explore the reasons behind the different prevalence of HIA in these two populations. Methods: Blood samples from all hemodialysis and cardiac surgery patients ...
Nakashima Ryo - - 2011
  To clarify the histological features and endoscopic classifications of nodular gastritis (NG).   Overall 40 996 patients who had undergone an upper gastrointestinal endoscopy were enrolled. NG is defined as a uniform and diffuse protrusion from the antrum to angulus, which has two types at endoscopy: nodular (N) and granular ...
Shetty Anoop K AK Guys and St Thomas' Hospital NHS Foundation Trust King's College London, London, UK. - - 2012
It is not clear whether there is a large difference in acute hemodynamic response (AHR) to left ventricle (LV) pacing in different regions of the same coronary sinus (CS) vein. Using the four electrodes available on a Quartet LV lead, we evaluated the AHR to pacing within individual branches of ...
Jung Hyung-Tae - - 2011
The ability to recognize facial affect is impaired in schizophrenia patients. This study compared source activities of the event-related potentials (ERPs) for affective facial pictures between schizophrenia patients and healthy controls. Twenty-three schizophrenia patients (11 females) and 24 healthy controls (12 females) were recruited. The standardized low-resolution brain electromagnetic tomography ...
Longo Giovanni - - 2011
Abstract Conclusions: In benign paroxysmal positional vertigo (BPPV), vestibular evoked myogenic potentials (VEMPs) help to better define the extent of saccular damage and the patient's prognosis. Objectives: To report the results of VEMPs in patients affected by BPPV of the posterior semicircular canal (PSC) in order to evaluate the presence ...
Bidad Katayoon - - 2011
The Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) and the Bath Ankylosing Spondylitis Functional Index (BASFI) are widely used instruments in assessment of patients suffering from ankylosing spondylitis (AS). The Patient Acceptable Symptom State (PASS) is regarded as a target for patients' well-being. The aim of this study was to ...
Delgado Pilar - - 2011
BACKGROUND: Lp-PLA2 is a novel biomarker in cardiovascular diseases due to its ability to predict first-ever and recurrent stroke. Little information is known regarding its influence on early outcome after stroke. OBJECTIVES: We aimed to investigate Lp-PLA2 in t-PA-treated stroke patients and to study its relationship with early outcome. METHODS: ...
Ando Hirohiko - - 2011
BACKGROUND: An increase in cystatin C (CyC) of ≥10% for 24 hours may predict contrast-induced nephropathy and worse outcomes in patients with renal dysfunction undergoing invasive coronary angiography. OBJECTIVE: We investigated the changes in CyC in patients with preserved renal function referred for contrast-enhanced coronary computed tomography angiography (CTA). METHODS: ...
Sun Qin - - 2011
INTRODUCTION:: The diagnosis value of adenosine deaminase (ADA) activity in cerebrospinal fluid (CSF) of tuberculous meningitis (TBM) has been well documented. However, the cutoff point of CSF ADA has not been fully assessed. In the current study, the authors set to calculate the cutoff points of ADA and monitor the ...
Dadu Razvan T - - 2011
BACKGROUND: The ventriculophasic response (VR) refers to shortening of atrial cycle length during heart block when a QRS complex is interposed between P waves. No formal quantitative definition has heretofore been proposed, nor have its potential clinical correlations been studied. HYPOTHESIS: We hypothesized that VR is present in selected patients ...
Kekunnaya Ramesh - - 2011
PURPOSE:To determine the demographic and clinical profile of various subtypes of Duane retraction syndrome (DRS). METHODS:Retrospective case series of 441 patients. RESULTS:Of the total 441 patients, 389 (88.2%) and 52 (11.8%) patients had unilateral and bilateral involvement, respectively. In both unilateral and bilateral cases, type I was the most common ...
Rawlings N G - - 2012
To report the clinicopathologic features of a series of patients with Melkersson-Rosenthal syndrome (MRS). Patients in this clinicopathological case series were identified through retrospective review. Five Caucasian patients (2 women and 3 men; age range, 46 to 73 years) with isolated eyelid swelling presented over an 11-month period to two ...
Fodor Eszter - - 2011
Purpose: To evaluate and compare tear osmolarity in different grades of conjunctivochalasis. Patients and methods: Forty subjects divided into four groups based on grading of conjunctivochalasis by lid-paralell conjunctival fold (LIPCOF) test and tear osmolarity evaluated by TearLab osmometer. Schirmer test, tear film break up time (BUT) and vital staining ...
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