Search Results
Results 201 - 250 of 2025
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Abelsson J - - 2011
Between 1982 and 2009 a total of 92 patients with myelofibrosis (MF) in chronic phase underwent allo-SCT in nine Nordic transplant centers. Myeloablative conditioning (MAC) was given to 40 patients, and reduced intensity conditioning (RIC) was used in 52 patients. The mean age in the two groups at transplantation was ...
Gribar John J - - 2011
Purpose: Some patients with severe carotid stenosis have anatomical or clinical comorbidities that place them at high risk for carotid endarterectomy (CEA). The early and late outcomes after carotid artery stenting (CAS) were evaluated in patients at high risk for CEA. Methods: Between 2002 and 2009, 186 patients were enrolled ...
Ishii Lisa E - - 2011
OBJECTIVES/HYPOTHESIS: To evaluate affect display in patients with facial paralysis as compared with normal subjects. We hypothesized that patients with facial paralysis would have impaired affect display and be perceived as displaying a negative affect as compared with normal subjects. STUDY DESIGN: Randomized controlled experiment. METHODS: Forty naive observers viewed ...
Leffers Henrik Christian - - 2011
To describe drug survival, disease activity and clinical response in patients with rheumatoid arthritis (RA) treated with abatacept or tocilizumab in routine care, based on prospectively registered observational data from the nationwide Danish DANBIO registry. 150 Patients with RA treated with abatacept and 178 treated with tocilizumab were identified. Drug ...
Iłżecka J - - 2011
There are evidence that extracellular matrix metalloproteinases (MMPs) may be implicated in the pathophysiology of amyotrophic lateral sclerosis (ALS). The extracellular matrix metalloproteinase inducer (EMMPRIN) is said to increase the production of MMPs in cells. The aim of the study was to investigate serum EMMPRIN levels in patients with ALS. ...
Giovacchini Giampiero - - 2011
PURPOSE: Administration of positively charged amino acids has been introduced to reduce the nephrotoxicity of targeted radiopeptide therapy (TRT). However, the amino acid solution may have side effects, including hyperkalaemia. The aim of this study was to evaluate the frequency and the magnitude of hyperkalaemia in neuroendocrine tumour (NET) patients ...
Asadi Mehdi - - 2011
BACKGROUND: The aim of this study was to assess the value of a technetium ((99m)Tc)-polyclonal antibody to detect acute appendicitis in patients with intermediate probability of appendicitis. METHODS: A total of 40 patients with mean age of 24.6 ± 6.9 years with intermediate probability of appendicitis according to the Alvarado scoring system (score ...
de Rooij N K - - 2011
The pathogenesis of secondary infarctions (SI) after aneurysmal subarachnoid hemorrhage (SAH) is poorly understood. To assess whether SI in single (SSI) or multiple (MSI) vascular territories represent different disease entities, we compared clinical profiles of patients with these patterns of SI. CT/MRI-examinations of 448 patients were reviewed for new infarctions ...
de Deus Cardoso Cejana Casimiro - - 2011
PURPOSE: To evaluate the clinical and radiologic response of patients with Graves' ophthalmopathy given low-dose orbital radiotherapy (RT) with a protracted fractionation. METHODS AND MATERIALS: Eighteen patients (36 orbits) received orbital RT with a total dose of 10 Gy, fractionated in 1 Gy once a week over 10 weeks. Of ...
Tóth László - - 2011
The pathomechanism of chronic rhinosinusitis with nasal polyposis (CRS/NP) seems to be unclear. Bacterial-, fungal- and combined biofilms might play a potential role in the pathogenesis of various inflammatory diseases and recently in CRS/NP. A prospective, blinded observational study was performed to confirm that the combination of conventional hematoxylin-eosin (HE) ...
Celik Gülperi - - 2011
Abstract Background: In this study, we aimed to determine the nasal carriage rate of Staphylococcus aureus and risk factors in hemodialysis (HD) patients. Methods: One hundred eighty-four HD patients were evaluated. A second sample was taken from the subjects, the wipe samples of whom were isolated as S. aureus. And ...
Jensen Peter - - 2011
Evidence is increasing that severe psoriasis is an independent cardiovascular risk factor. Results from case-control studies of endothelial dysfunction, a marker of early atherosclerosis, in patients with moderate-to-severe psoriasis have been conflicting and were conducted with operator-dependent and technically demanding ultrasound measurement of brachial artery flow-mediated vasodilation. Therefore, we decided ...
Blumin Joel H - - 2011
OBJECTIVES/HYPOTHESIS: Idiopathic subglottic stenosis (iSGS) is a disease predominantly of females that, by definition, has no known etiology. Collagen-vascular disease, localized trauma, extraesophageal reflux (EER), and hormonal alterations have all been postulated as potential etiologies of iSGS. It is hypothesized that iSGS is a reflux mediated disease and that evidence ...
Sagdic A - - 2011
INTRODUCTION: This study was conducted to evaluate the oxidant/antioxidant balance (oxidative stress status) and plasma essential trace element levels in patients with bronchial asthma or allergic rhinitis. METHODS: A total of 94 individuals consisting of 19 allergic asthmatics; 17 non-allergic asthmatics; 22 patients with allergic rhinitis; and 36 healthy control ...
Karakurt Cemşit - - 2011
OBJECTIVE: The aim of our study was to investigate the association of HLA antigens and a non-HLA protein D8/17 with rheumatic heart disease and its pattern of cardiac involvement. METHODS: This cross- sectional observational study included 35 children and 12 adult patients who have rheumatic heart disease and 35 healthy ...
Chang Chun-Shin - - 2011
INTRODUCTION: Abnormalities of the first rib including rib width, rib shape and rib angulation were noted intra-operatively in our thoracic outlet syndrome (TOS) operative patients. The purpose of this study is to investigate the relationship between TOS and the first rib in TOS operative patients and normal population. METHODS: Between ...
Montés-Micó Robert - - 2011
PURPOSE.: To evaluate accommodative response and facility in presbyopic patients fitted with several types of simultaneous-image multifocal contact lenses (CLs). METHODS.: Six presbyopic patients, unadapted wearers of simultaneous-image bifocals, were fitted with the Focus Progressives and the low- and high-addition Pure Vision simultaneous vision multifocal CLs. Each individual wore each ...
Agarwal Rajiv - - 2011
The purpose of this study was to evaluate the levels and patterns of total and differential leukocyte counts and their prognostic importance in a cohort of people with and without chronic kidney disease (CKD). Among 153 veterans without CKD and 267 with, blood leukocyte count was measured at baseline and ...
Olm Mary A K - - 2011
Ciliary beat frequency (CBF) measurements provide valuable information for diagnosing of primary ciliary dyskinesia (PCD). We developed a system for measuring CBF, used it in association with electron microscopy to diagnose PCD, and then analyzed characteristics of PCD patients. The CBF measurement system was based on power spectra measured through ...
Nussinovitch Udi - - 2011
There is a paucity of knowledge regarding the autonomic nervous system function in patients with familial Mediterranean fever (FMF). Therefore, our aim was to evaluate autonomic responses in patients with FMF using complementary tests. The study groups included 33 patients with uncomplicated FMF and 39 control subjects. Autonomic function was ...
Dvortsin Dima P - - 2011
Abstract Objective: To introduce a simple and reliable method to reorient lateral radiographs to the natural head position (NHP) according to standardized photographs made at NHP. Material and Methods: The study has two parts. In the first part, 45 patients were randomly selected from a patient cohort. Photographs (at NHP) ...
Palani Gurunanthan - - 2011
BACKGROUND: Pharmacokinetic studies suggest delayed clearance of Regadenoson (REG), a new selective A2A receptor agonist in chronic kidney disease (CKD). The safety of REG in large series of CKD patients in daily clinical practice remains unstudied. METHODS: Retrospective study of patients with eGFR < 60 mL/min (n = 411, Grp 1, CKD) were compared to ...
Nunes Jean Costa - - 2011
Epilepsy and headache are two chronic disorders that are characterized by recurrent attacks, but the relationship between them is not completely understood. Using a structured questionnaire, we investigated the prevalence of headache during the previous year in a homogeneous group of 100 patients with mesial temporal lobe epilepsy with hippocampal ...
Aggarwal Niti R - - 2011
BACKGROUND: Contrast enhanced Multislice Computed Tomographic Angiography (MSCTA) detects non-calcified plaque (NCP) in coronary arteries and associated coronary stenoses. However, the clinical relevance of NCP is poorly defined. OBJECTIVES: Our goal was to examine the relationship NCP, risk factors and clinical follow up in unselected outpatients undergoing MSCTA. METHODS: Five ...
Amin Amanda L - - 2011
PURPOSE: Previous studies have suggested that primary hyperparathyroidism (pHPT) with only normal parathyroid hormone (PTH) levels is a milder, less symptomatic form of pHPT. This study investigates symptoms, laboratory values, imaging, and outcomes of sporadic pHPT patients with normal PTH values. METHODS: We reviewed our prospectively collected database of 861 ...
Gerbaud Edouard - - 2011
To evaluate the incremental diagnostic and prognostic value of cardiac magnetic resonance (CMR) in patients with chest pain, raised troponin and unobstructed coronary arteries, and to compare subsequent event rates between diagnostic groups. 130 patients (mean age: 54 ± 17) presenting with troponin-positive acute chest pain and unobstructed coronary arteries were included. ...
Santanna A - - 2011
Movement asymmetry is one of the motor symptoms associated with Parkinsons Disease (PD). Therefore, being able to detect and measure movement symmetry is important for monitoring the patients condition. The present paper introduces a novel symbol based symmetry index calculated from inertial sensor data. The method is explained, evaluated and ...
Spiewak Mateusz - - 2011
To compare right ventricular (RV) size and function between patients with combined pulmonary regurgitation (PR) plus RV outflow tract (RVOT) obstruction (RVOTO) and patients with isolated PR. Consecutive individuals with significant PR (PR fraction ≥20%) after tetralogy of Fallot (TOF) repair who underwent cardiovascular magnetic resonance (CMR) were included. Patients ...
Cusmà Piccione Maurizio - - 2011
Vascular involvement in systemic sclerosis (SSc) plays a key role in the pathogenesis of fibrosis. We assessed arterial stiffness using a new echo-tracking technique in patients with SSc asymptomatic for cardiovascular diseases. We enrolled 22 patients (21 female, 63 ± 14 years) and 20 controls (12 female, 62 ± 3 ...
Pahade Jay K - - 2011
The purpose of this article is to evaluate the incidence of contrast-induced nephropathy (CIN) and the effects of associated risk factors in patients with multiple myeloma undergoing contrast-enhanced CT (CECT) with IV administration of nonionic iodinated contrast agent. This retrospective review of medical records identified patients with a diagnosis of ...
De Luca Giuseppe - - 2011
Few reports have so far investigated the relationship between fibrinogen levels and the extent of coronary artery disease (CAD) as evaluated by coronary angiography, that is therefore the aim of the current study. We measured fibrinogen in 2,121 consecutive patients undergoing coronary angiography. Patients were divided in 5 groups based ...
Martin-Blondel Guillaume - - 2011
Cannabis implication in the pathophysiology of distal arteritis remains controversial. The aim is to assess whether cannabis co-exposure influences presentation and outcome of thromboangiitis obliterans (TAO) in tobacco smokers. All consecutive patients presenting with a definite TAO were retrospectively reviewed according to their tobacco and cannabis consumption status. A total ...
Singhal Ash - - 2011
Object In general, patients who present with low Glasgow Coma Scale (GCS) scores and/or fixed and dilated pupils are not expected to do well following arteriovenous malformation (AVM) hemorrhage. However, there is a sense among neurosurgeons that pediatric patients may make a better recovery than adults following such an event. ...
Dinh T - - 2011
BACKGROUND: Antithrombotic management in atrial fibrillation (AF) is currently based on clinical characteristics, despite evidence of potential fine-tuning with transoesophageal echocardiography (TEE). This open, randomised, multicentre study addresses the hypothesis that a comprehensive strategy of TEE-based aspirin treatment in AF patients is feasible and safe. METHODS: Between 2005 and 2009, ...
Khalil E A - - 2011
Background: Tuberculous lymphadenitis (TL) is the commonest form of extra-pulmonary tuberculosis in tropical countries. Objective: This study aimed to characterize in vivo and in vitro cellular immune responses to Mycobacterium PPD in TL patients as markers of disease and healing. Methods: Following informed consent, 36 TL patients, 40 patients with ...
Sun Yi-Chen - - 2011
To explore the presentations of matrix metalloproteinases (MMPs) and their tissue inhibitors (TIMPs) in superior limbic keratoconjunctivitis (SLK) with typical redundant superior conjunctiva. Eight surgical specimens from medically refractory SLK patients were examined. Another nine conjunctival specimens from patients who underwent cataract and retinal surgery served as controls. Expression of ...
Causey Marlin Wayne - - 2011
Hemoglobin levels must be obtained through blood draws, which are invasive, time-consuming, and provide only 1 data point at a time rather than continuous measurements. The Masimo Radical-7 SpHb Station (Masimo Corporation, Irvine, CA) has been shown by its manufacturers to provide accurate noninvasive hemoglobin measurements in physiologically normal patients. ...
Kang Jiunn-Horng - - 2011
Background/Aims: Previous studies have suggested that hepatic (toxic-metabolic) encephalopathy, the major complication of cirrhosis, is a neuropsychiatric disorder typically seen in patients with liver dysfunction after exclusion of other known brain disease. This study aims to investigate the risk for parkinsonism during a 7-year follow-up period after a diagnosis of ...
Görgülü Serkan - - 2011
The aim of this study was to evaluate the position and movements of the tongue in patients with skeletal Class III malocclusion. Sixty-six patients (31 male, 35 female) with Class III malocclusion were divided into 3 groups according to cephalometric analysis. The first group comprised 23 patients (13 male, 10 female) ...
Sharma P - - 2011
Patients with cirrhosis who undergo endoscopy under sedation could be at increased risk of complications. We assessed the utility of the critical flicker frequency (CFF) in the recovery of cognitive function. This was a prospective study in patients with cirrhosis who underwent endoscopy under sedation with propofol in a tertiary ...
Weil Alexander G - - 2011
Objective: Decompressive hemicraniectomy (DH) has been shown to reduce mortality in patients with malignant middle cerebral artery (MCA) territory infarction. However, many patients survive with moderate-to-severe disability and controversy exists as to whether this should be considered good outcome. To answer this question, we assessed the quality of life (QoL) ...
Azad Sheenam - - 2011
Ulcerative colitis is a chronic inflammatory disease of unknown etiology characterized by periods of remission and relapses. This study has been carried out in a group of North Indian patients, where the disease has shown an increasing prevalence and frequent relapses. Hence, there is a need to predict relapse for ...
Reinker Kent - - 2011
Kyphoscoliosis is considered a relative contraindication to treatment with the Vertical Expandable Prosthetic Titanium Rib (VEPTR(®); Synthes Inc, Paoli, PA). Nevertheless, patients do present with early-onset kyphoscoliosis and thoracic insufficiency syndrome, and no suitable alternative treatments are currently available. However, it is unclear whether VEPTR(®) is reasonable for treating patients ...
Dufton John A JA Department of Diagnostic Radiology, Kingston General Hospital, Queen's University, Toronto, Ontario, - - 2011
To determine if there is a correlation between cerebellar tonsillar descent in patients with and without Chiari I malformation and three skull morphometric measurements: clivus length, anteroposterior diameter of the foramen magnum, and Boogard's angle. Cerebellar tonsillar descent, clivus length, anteroposterior diameter of the foramen magnum, and Boogard's angle were ...
Zangari Maurizio - - 2011
Increased risk of venous thromboembolism (VTE) has been described in multiple myeloma patients, particularly when exposed to immunomodulatory drugs. Epidemiological studies have shown that monoclonal gammopathy of undetermined significance (MGUS) patients also have an increased risk of VTE compared with normal individuals. Acquired activated protein C resistance (APC-R) is an ...
Klingenstein Annemarie - - 2011
The serological marker melanoma inhibitory activity (MIA) has been shown to be significantly higher in the serum of patients suffering from metastatic uveal melanoma than in progression-free patients. The objective of this study was to calculate a meaningful receiver operating characteristic (ROC) curve for MIA based on a large patient ...
Blondeau K - - 2011
Background  Increased body weight is associated with higher intragastric pressure. Proximal extent of reflux is a determinant of symptoms in patients with gastro-esophageal reflux disease (GERD). We aimed to investigate the association between body mass index (BMI) and abdominal circumference on the incidence and proximal extent of reflux. Methods  A ...
Seguin J - - 2011
OBJECTIVE: To describe CSF biomarker profiles in posterior cortical atrophy (PCA), which induces high-order visual deficits often associated with Alzheimer disease (AD) pathology, and relate these findings to clinical and neuropsychological assessment. METHODS: This prospective observational study included 22 patients with PCA who underwent CSF biomarker analysis of total tau ...
Mühl Diána - - 2011
PURPOSE: Little is known about the dynamic changes of matrix metalloproteinases (MMPs) and their inhibitors (TIMPs) in sepsis. Our aim was therefore to investigate the time course of MMPs and their inhibitors in patients experiencing severe sepsis. METHODS: Our prospective controlled analysis included 38 patients with severe sepsis. Plasma levels ...
Aminaka Naoko - - 2011
The aim of the study was to investigate differences in frontal plane knee kinetics, onset timing and duration of the gluteus medius (GMed), adductor longus (AL), and vastus medialis oblique (VMO) during stair ambulation between those with and without patellofemoral pain syndrome (PFPS). Twenty PFPS patients and twenty healthy participants ...
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