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Moré Jayaji M JM *Department of Radiation Oncology; †Center for Atmospheric and Environmental Chemistry, Aerodyne Research Inc., Billerica, MA; ‡School of Nursing, University of Pennsylvania, Philadelphia, PA; §Kos Partners, Burlingame, CA; ‖Stanford Cancer Institute, Stanford University School of Medicine, Stanford, CA; and ¶Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, - - 2014
In this prospective pilot study, we evaluated the feasibility and potential utility of measuring multiple exhaled gases as biomarkers of radiation pneumonitis (RP) in patients receiving stereotactic ablative radiotherapy (SABR) for lung tumors. Breath analysis was performed for 26 patients receiving SABR for lung tumors. Concentrations of exhaled nitric oxide ...
Hale Melissa F MF Melissa F Hale, Reena Sidhu, Mark E McAlindon, Department of Gastroenterology, Royal Hallamshire Hospital, Sheffield S10 2JF, United - - 2014
Capsule endoscopy (CE) has transformed investigation of the small bowel providing a non-invasive, well tolerated means of accurately visualising the distal duodenum, jejunum and ileum. Since the introduction of small bowel CE thirteen years ago a high volume of literature on indications, diagnostic yields and safety profile has been presented. ...
Aytekin S S Department of Dermatology, Faculty of Medicine, Ondokuz Mayis University, Samsun, - - 2014
Nailfold capillaroscopy is used for the identification of microvascular involvement in many rheumatic and extrarheumatic diseases. To determine the nailfold capillary changes in patients with Behçet disease (BD) by videodermoscopy, i.e. nailfold videocapillaroscopy (NVC). We used a videodermatoscope (Molemax II, × 30 magnification) to perform nailfold capillaroscopy on 40 patients with ...
Gupta A - - 2013
BACKGROUND AND PURPOSE:Increased oxygen extraction fraction on PET has been considered a risk factor for stroke in patients with carotid stenosis or occlusion, though the strength of this association has recently been questioned. We performed a systematic review and meta-analysis to summarize the association between increased oxygen extraction fraction and ...
Hofstee H M A - - 2013
Chronic GVHD (cGVHD) complicating allo-SCT commonly presents as sclerotic skin changes resembling systemic sclerosis (SSc), suggesting a common pathophysiological pathway. Damage to capillaries is considered an early event in the pathogenesis of SSc, and is associated with characteristic nailfold capillary abnormalities. Whether such nailfold capillary abnormalities occur in sclerodermatous cGVHD ...
Uihlein Lily C - - 2013
Regional capillary malformation of a lower extremity is associated with the overgrowth of bone or soft tissue in several disorders, most commonly Klippel-Trenaunay syndrome and Parkes Weber syndrome. We have observed a subset of patients with a capillary malformation of the leg, minor growth disturbance, and prominent veins. The objective ...
Schmidt C - - 2013
/st>Microcirculatory alterations play a central role in the pathophysiology of sepsis. We investigated probe-based confocal laser endomicroscopy (pCLE) to assess alterations in mucosal microcirculatory perfusion in vivo in a porcine model of septic shock and in patients fulfilling consensus criteria for severe sepsis. /st>Septic shock was induced using a faecal ...
Sekiyama Juliana Y - - 2013
Objective. To analyze the diagnostic performance and the reliability of different parameters evaluated by widefield nailfold capillaroscopy (NFC) with those obtained by videocapillaroscopy in patients with Raynaud's phenomenon (RP). Methods. Two-hundred and fifty-two individuals were included: 101 systemic sclerosis (SSc) patients, 61 patients with undifferentiated connective tissue disease, 37 with ...
Keo Hong H - - 2013
Fluorescence microlymphography (FML) is used to visualize the lymphatic capillaries. A maximum spread of the fluorescence dye of ≥ 12 mm has been suggested for the diagnosis of lymphedema. However, data on sensitivity and specificity are lacking. The aim of this study was to investigate the accuracy of FML for ...
Dogan Sibel - - 2013
BACKGROUND: Vasculopathy is known to destroy nailfold capillary pattern (NCP) in systemic sclerosis (SSc). There are several methods for the evaluation of NCP of which the most common are dermatoscopy and videocapillaroscopy (VCAP). No study has been reported in the literature comparing these two techniques for their diagnostic value. OBJECTIVE: ...
Pan Ping - - 2013
This study evaluated the consistency of manual and automated measurements of monodominant follicle diameter with different follicle size in infertile patients. Transvaginal two-dimensional (2D) ultrasound and SonoAVC (Sonography-based Automated Volume Calculation) were both performed in 226 infertile patients with monodominant follicle growth. 2D diameters were separately compared with SonoAVC-generated d(V) ...
Graceffa Dario D Centre for the Study and Treatment of Psoriasis, Department of Clinical Dermatology, San Gallicano Dermatological Institute (IRCCS), Rome, - - 2013
Impairment of capillaries permeability and changes of microcirculation are associated with inflammatory arthritis. In order to demonstrate microvascular differences between psoriatic arthritis (PsA) and rheumatoid arthritis (RA) we analyzed capillaroscopic abnormalities such as megacapillaries, haemorrhages, ramifications, and avascular areas in patients affected by these two rheumatic disorders. Moreover to identify ...
Kawanishi Kunio K Department of Medicine, Kidney Center, Tokyo Women's Medical University, Tokyo, - - 2013
The effects of novel biocompatible peritoneal dialysis (PD) solutions on human peritoneal membrane pathology have yet to be determined. Quantitative evaluation of human peritoneal biopsy specimens may reveal the effects of the new solutions on peritoneal membrane pathology. ♢ Peritoneal specimens from 24 PD patients being treated with either acidic ...
Archid Rami - - 2012
ABSTRACT. An important and most likely active role in the pathogenesis of psoriasis has been attributed to changes in cutaneous blood vessels. The purpose of this study was to use confocal laser-scanning microscopy (CLSM) to investigate dermal capillaries in psoriatic and normal skin. The structures of the capillary loops in ...
Healey Jeff S - - 2012
BACKGROUND: -In animal models of atrial fibrillation (AF), changes in atrial electrophysiologic (EP) properties are associated with the development of AF. Their relevance to human AF is unclear. METHODS AND RESULTS: -The ASSERT trial enrolled 2580 patients receiving a dual-chamber pacemaker, who were over the age of 65 years and ...
Sairaku Akinori - - 2012
BACKGROUND: Atrioventricular (AV) conduction disturbances have often been considered as an etiology of prolonged pauses during atrial fibrillation (AF). We aimed to test whether there was a significant difference in the AV conduction properties between patients with and without clinically significant pauses who underwent ablation of longstanding persistent AF. METHODS: ...
Liao Zili - - 2011
Atriofascicular and decremental atrioventricular pathways are variants of accessory pathways with anterograde decremental conduction properties. They result in typical wide Quantronic Resonance System (QRS) tachycardia of left bundle branch block morphology. Data on the sinus rhythm electrocardiographic characteristics are limited. Thirty patients with accessory pathways of anterograde decremental conduction properties ...
Pfiffner P - - 2010
Cross reactions are an often observed phenomenon in patients with allergy. Sensitization against some allergens may cause reactions against other seemingly unrelated allergens. Today, cross reactions are being investigated on a per-case basis, analyzing blood serum specific IgE (sIgE) levels and clinical features of patients suffering from cross reactions. In ...
González-de-Olano D - - 2010
BACKGROUND:: Basophil activation tests (BATs) have been demonstrated to be useful in detecting IgE-mediated sensitization by measuring basophil activation surface markers (CD63 and CD203c). Hymenoptera venom is one of the best known mediators-release trigger in patients with systemic mastocytosis (SM). The aim of this study was to investigate the use ...
Hirano Kenji K Department of Gastroenterology, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan. - - 2010
To clarify the clinical significance of high serum IgE in autoimmune pancreatitis (AIP). Forty-two AIP patients, whose IgE was measured before steroid treatment, were analyzed. To evaluate the relationship between IgE levels and the disease activity of AIP, we examined (1) Frequency of high IgE (> 170 IU/mL) and concomitant ...
Bachert Claus - - 2010
Nasal polyps often are associated with asthma. The phenotype of these patients is unknown. To identify the mucosal factors associated with asthma comorbidity, we analyzed the inflammatory patterns of nasal polyps. Nasal polyps from 70 Belgian patients, 34% with asthma, were analyzed for type of inflammation, T-cell cytokines, and IgE ...
Mladina Ranko - - 2010
Posterior fontanelle defects were found in almost half of the patients with postnasal drip and in a negligible number in the cohort of healthy subjects. The aim of this study was to compare the incidence of fontanelle defects in patients with postnasal drip and in healthy subjects. A total of ...
Hirshoren Nir - - 2011
Angiogenesis may be related to the pathogenesis and prognosis of chronic rhinosinusitis with nasal polyposis. This cross-sectional study, in a tertiary university hospital, evaluates angiogenesis parameters in nasal polyps, antrochoanal polyps and middle turbinates. Nasal polyps obtained from 24 consecutive patients, were compared to 10 normal middle turbinates and to ...
Frezzolini A - - 2010
BACKGROUND: The basophil activation test (BAT) has been recently described as a useful in vitro tool for diagnosis of allergy to Anisakis species in patients with acute urticaria. AIM: To evaluate the relationship between sensitization to Anisakis simplex and chronic urticaria (CU), using flow cytometry analysis of in vitro BAT. ...
Derebery M Jennifer - - 2010
Ménière's disease (MD), which by definition is idiopathic, has been ascribed to various causes, including inhalant and food allergies. Patients with MD report higher rates of allergy history and positive skin or in vitro tests compared with a control group of patients with other otologic diseases and to the general ...
Ciprandi Giorgio - - 2011
Background: Th9 is a new T cell subset characterized by interleukin 9 (IL-9) production. Serum IL-9 levels are related to symptom severity in patients with allergic rhinitis (AR). This study aimed at investigating whether IL-9 may depend on allergen exposure. Methods: 35 AR patients (16 males, mean age 33.2 years) ...
Valdivieso R - - 2011
Seasonal variation of Dermatophagoides allergens and its influence in allergic respiratory airway diseases has not been investigated in Andean cities. The objective of this study was to evaluate those parameters in a city located in the Andean mountains. Der p1 and Der f1 were measured in dust samples from mattresses ...
Bassiouny Ahmed - - 2011
The objective of the study was to define the true incidence of fungal elements in the nasal and sinus mucous in cases of chronic rhinosinusitis (CRS) with bilateral polyposis compared with normal controls-in an Egyptian African population-via mycological and histologic techniques. This study was conducted prospectively on 100 patients with ...
Wu X T - - 2010
The aim of this study was to investigate the association between carbamazepine (CBZ)-induced cutaneous adverse drug reactions (cADRs) and the HLA-B*1502 allele among patients from central China. Eight patients with Stevens-Johnson syndrome and toxic epidermal necrolysis (SJS/TEN), 28 with mild maculopapular eruptions (MPEs), 50 CBZ-tolerant controls, and 71 healthy volunteers ...
Reed Jo - - 2010
We asked if certain clinical features were useful predictors of sarcoid rhinosinusitis in general populations of patients with chronic rhinosinusitis. Our patients with sarcoid rhinosinusitis and those from the literature formed the study group. A group of 21 randomly selected patients from The University of Mississippi Medical Center Allergy Clinic ...
Schmid Christoph - - 2010
OBJECTIVE: To investigate the hypothesis that eosinophil major basic protein is released in high concentrations in the nasal mucus of patients with polypoid chronic rhinosinusitis. STUDY DESIGN: Single center, open, prospective trial. SETTING: Medical University of Graz, Austria. SUBJECTS AND METHODS: Patients with polypoid chronic rhinosinusitis (n = 23) were ...
Yu Kathy - - 2010
To assess the subjective aesthetic and functional concerns of patients seeking revision rhinoplasty and to compare them with objective deformities found on evaluation by the surgeon. This prospective study used a questionnaire to systematically target the aesthetic and functional concerns of 104 consecutive patients seeking revision rhinoplasty. Analysis of the ...
Elmorsy Shawky - - 2010
In patients with chronic fungal sinusitis, concentrations of interleukin-8 (IL-8), immunoglobulin E (IgE), and soluble intercellular adhesion molecule-1 (sICAM-1) were compared in paranasal sinus aspirates and serum. Furthermore, immunological effects of macrolide treatment of our patients with chronic fungal rhinosinusitis were also studied. In our cohort study, 108 patients with ...
Daschner Alvaro - - 2010
The relationship between atopic sensitization and chronic urticaria is still controversial. In this study, we aimed to compare the prevalence of aeroallergen sensitization in chronic urticaria patients with (CU/As+) and without (CU/As-) sensitization against Anisakis simplex. Forty-nine CU/As+ and 80 CU/As- patients were studied and skin prick tests (SPT) were ...
Bonadonna Patrizia - - 2010
PURPOSE OF REVIEW: To analyse the association of systemic allergic hymenoptera sting reactions with mastocytosis and elevated baseline serum tryptase and to discuss diagnosis and treatment in patients with both diseases. RECENT FINDINGS: In recent large studies on patients with mastocytosis a much higher incidence of severe anaphylaxis following hymenoptera ...
Grippaudo Francesca Romana - - 2010
BACKGROUND: Dermal fillers are used widely; some have a permanent effect, whereas others are temporary. The aim of this study is to describe the ultrasonographic features of permanent and temporary fillers injected into patients for cosmetic purposes. MATERIALS AND METHODS: Between December 2006 and April 2009, 36 subjects, aged 25-45, ...
Kirtsreesakul Virat - - 2010
OBJECTIVE: To evaluate the effect of IgE-mediated hypersensitivity on mucociliary clearance time (MCCT) and clinical severity, as indicated by total nasal symptoms score (TNSS) and peak expiratory flow index (PEFI). DESIGN: A prospective cross-sectional study. SETTING: Tertiary medical center. PARTICIPANTS: One hundred twenty-nine patients with rhinitis and 48 healthy control ...
Asha'ari Zamzil Amin - - 2010
Allergic rhinitis (AR) is a prevalent disease worldwide but is still underdiagnosed in many parts of Asia. We studied the clinical profiles of AR patients in our community based on the new ARIA classification and investigated the aetiological allergens using a skin prick test. In 2008, 142 newly diagnosed patients ...
Daschner Alvaro - - 2010
Acute urticaria is defined as evanescent wheals with a duration period of up to 6 weeks. Yet within acute urticaria, IgE-mediated urticaria lasts rarely more than 48 h, whereas longer duration periods are frequently unfruitful with respect to diagnostic work-up. We hypothesize the differences in immunologic features in immediate type ...
Buske-Kirschbaum A - - 2010
Previously we could demonstrate attenuated responsiveness of the hypothalamus-pituitary-adrenal (HPA) axis to stress in patients with chronic allergic inflammatory disease (i.e., atopic dermatitis, allergic asthma). The present study was designed to investigate HPA axis function in an acute manifestation of allergy. Patients with seasonal allergic rhinitis (SAR; n = 20) ...
Vermani Maansi - - 2011
Aspergillus-derived inhalant allergens play an important role in the etiology of allergic respiratory diseases. In the present study, we investigated the allergenic potential of Aspergillus tamarii, quantified its airborne content, identified its major/minor allergens, evaluated heterogeneity of patients' IgE response to its allergens and cross-reactivity of its allergens with other ...
Nikakhlagh S - - 2010
BACKGROUND: Nasal polyposis is the benign protrusion of soft tissue into the nasal cavity, with multifactorial origin. This study is designed to examine the suggested role of IgE and CD4 and CD8 lymphocytes in the pathogenesis of nasalpolyposis. METHODOLOGY: Blood samples were taken from 32 patients with chronic polypoid sinusitis ...
Summer Burkhard - - 2010
BACKGROUND: Some nickel (Ni) allergic patients develop complications following Ni-containing arthroplasty. In the peri-implant tissue of such patients, we had observed lymphocyte dominated inflammation together with IFN-gamma and IL-17 expression. OBJECTIVES: To determine whether Ni stimulation of peripheral blood mononuclear cells (PBMCs) of such patients would lead to a different ...
Barthelmes L - - 2010
Patent blue dye V (PBV) is in widespread use for sentinel node biopsy in breast cancer and melanoma. At present, the best diagnostic approach in investigating possible anaphylaxis due to PBV is not defined. We reviewed our experience of patients and the cases reported in the literature that developed an ...
Ruëff Franziska - - 2010
BACKGROUND: Severe side effects during venom immunotherapy (VIT) are associated with a variety of risk factors. OBJECTIVE: Our aim was to evaluate the association of baseline serum tryptase concentration (BTC) and of other parameters, which are routinely recorded during patient evaluation, with the frequency of severe reactions requiring an emergency ...
Bakhshaee Mehdi - - 2011
Allergic inflammation in upper airways can act as a predisposing factor for infectious ear diseases. There are some evidences about the role of allergic rhinitis in chronic otitis media with effusion, but its role in establishing chronic suppurative otitis media (CSOM) has not been clearly shown. 68 adult patients with ...
Mertens M - - 2010
In hymenoptera-venom allergy, sera of up to 60% of patients show in vitro reactivity to honeybee venom (HBV) and yellow jacket venom (YJV). This phenomenon is mainly caused by specific IgE (sIgE) against cross-reactive carbohydrate determinants (CCD). Whether or not these antibodies can induce clinical symptoms is a longstanding debate. ...
Lalek N - - 2010
BACKGROUND: The effects of pollen immunotherapy on effector cells of allergic inflammation, such as mast cells and basophils, are poorly understood. OBJECTIVE: For this reason, we conducted an open study on basophil allergen threshold sensitivity during birch pollen immunotherapy. METHODS: Basophil sensitivity was measured by CD63 flow cytometry in 14 ...
Armengot Miguel - - 2010
Primary ciliary dyskinesia (PCD) is a clinically uniform entity, although cilia motility and structure can vary among patients, making diagnosis difficult. Chronic sinusitis, bronchiectasis, sinus hypoplasia, secretory otitis media, and low fertility are common in PCD patients. The aim of this work was to correlate nasal ciliary activity with clinical ...
Kravos Alenka - - 2010
AIM: To identify the role of allergy in the occurrence of Reinke's edema on vocal folds. METHODS: This was a prospective study in patients with Reinke's edema on vocal folds (n = 80) and a control group of patients without Reinke's edema (n = 80). All the patients were examined ...
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