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Govindan Rathinaswamy B RB Division of Fetal and Transitional Medicine, Children's National Medical Center, Washington, DC, - - 2014
The objective of the study was to perform serial magnetomyographic examinations in order to detect changes in synchrony characteristics of myometrial electrophysiological activity as women approach labor. Of the total of 56 patients recruited, the results of 149 examinations from 29 patients were included in the analysis. The global synchrony ...
Dige Anders A Gastro-Immuno Research Laboratory (GIRL), Department of Hepatology and Gastroenterology, Aarhus University Hospital, 8000, Aarhus C, Denmark; Department of Medicine, Horsens Regional Hospital, 8700, Horsens C, - - 2014
Activated macrophages shed the haemoglobin-haptoglobin scavenger receptor CD163 into the circulation as soluble(s)-CD163. We measured sCD163 as an in vivo macrophage activation marker in patients with Crohn's disease (CD) or ulcerative colitis (UC) receiving anti-tumour necrosis factor (TNF)-α antibody or prednisolone treatment. We also investigated the CD163 expression on circulating ...
Savage E M EM Department of Rheumatology, Musgrave Park Hospital, Stockman's Lane, Belfast, BT9 7JB, Northern Ireland, UK, - - 2014
To determine whether rheumatoid arthritis disease activity correlates with changing weather conditions. A longitudinal analysis of 133 patients attending the Department of Rheumatology, Musgrave Park Hospital, Belfast was performed. Participants had a diagnosis of rheumatoid arthritis and were receiving subcutaneous anti-TNF therapy (Adalimumab or Etanercept) for a period of >6 months. ...
Vajaria Bhairavi N BN Biochemistry Research Division, The Gujarat Cancer & Research Institute, Asarwa, Ahmedabad, 380 016, Gujarat, - - 2014
Alterations in cell membrane glycosylation play important role in oral carcinogenesis. The present study evaluated salivary sialylation changes i.e. total sialic acid (TSA), sialidase activity, linkage specific (α2-3 and α2-6) sialoproteins and sialyl transferase (ST) activity in controls, patients with oral precancerous conditions (OPC) and oral cancer. Subjects enrolled included ...
Sambataro Domenico - - 2014
IntroductionNailfold videocapillaroscopy (NVC) in systemic sclerosis (SSc) is a procedure commonly used for patient classification and sub-setting, but not to define disease activity (DA). This study aimed to evaluate whether the number of micro-haemorrhages (MHE), micro-thrombosis (MT), giant capillaries (GC), and normal/dilated capillaries (Cs) in NVC could predict DA in ...
Carlier T T Nuclear Medicine Department, University Hospital of Nantes, Nantes, France. CRCNA, UMR 892 INSERM, Nantes, - - 2014
The injected activity and the acquisition time per bed position for 18F-FDG PET scans are usually optimized by using metrics obtained from phantom experiments. However, optimal activity and time duration can significantly vary from a phantom set-up and from patient to patient. An approach using a patient-specific noise equivalent count ...
London E E Section on Endocrinology & Genetics, Program on Developmental Endocrinology & Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), Bethesda, MD, - - 2014
The cAMP signaling pathway is implicated in bilateral adrenocortical hyperplasias (BAHs), which are often associated with ACTH-independent Cushing syndrome (CS). Although CS is invariably associated with obesity and is frequently associated with PKA signaling defects, we recently reported that its different forms appear to also present with variable weight gain ...
Milos M M Department of Laboratory Diagnostics, University Hospital Centre Zagreb, Zagreb, - - 2014
Diagnosis of haemophilia A is usually made by the measurement of factor VIII (FVIII) activity that allows categorization of the disease severity. However, tests that assess global haemostasis may better reflect clinical features and give additional clinically relevant information. The aim of this study was to develop a new quantitative ...
Forgacs Peter B PB Feil Family Brain and Mind Research Institute, Department of Neurology; The Rockefeller University, New York, NY, 10065, - - 2014
Objective: Standard clinical characterization of patients with disorders of consciousness (DOC) relies on observation of motor output and may therefore lead to the misdiagnosis of vegetative state (VS) or minimally conscious state (MCS) in patients with preserved cognition. We used conventional electroencephalographic (EEG) measures to assess a cohort of DOC ...
Berard Roberta A RA From Western University; Children's Hospital, London Health Sciences Centre, London; Division of Clinical Decision Making and Health Care, Toronto General Research Institute, University Health Network; Division of Rheumatology, the Hospital for Sick Children; Cell Biology Program, the Hospital for Sick Children Research Institute; Department of Pediatrics, Department of Health Policy, Management and Evaluation, Dalla Lana School of Public Health, Department of Immunology, and the Department of Medical Science, University of Toronto; Institute for Work and Health, and Division of Rheumatology, Mount Sinai Hospital; Department of Medicine, University Health Network and Mount Sinai Hospital, Toronto, Ontario; University of Manitoba; Children's Hospital, Health Sciences Centre, Winnipeg, Manitoba; University of Saskatchewan, Saskatoon, Saskatchewan, Canada. Supported by the Canadian Institutes of Health Research Grant # IIN84042. Dr. Yeung is supported by an investigator award from The Arthritis Society of Canada. R.A. Berard, MD, MSc, Western University, Children's Hospital, London Health Sciences Centre; G. Tomlinson, PhD, Division of Clinical Decision Making and Health Care, Toronto General Research Institute, University Health Network, and the Department of Health Policy, Management and Evaluation, and the Dalla Lana School of Public Health, University of Toronto, and the Department of Medicine, University Health Network and Mount Sinai Hospital; X. Li, MD, BSc, Division of Clinical Decision Making and Health Care, Toronto General Research Institute, University Health Network; K. Oen, MD, University of Manitoba, Children's Hospital, Health Sciences Centre; A.M. Rosenberg, MD, University of Saskatchewan; B.M. Feldman, MD, MSc, Division of Rheumatology, the Hospital for Sick Children, and the Department of Pediatrics, Department of Health Policy, Management and Evaluation, and the Dalla Lana School of Public Health, University of Toronto; R.S.M. Yeung, MD, PhD, Division of Rheumatology, the Hospital for Sick Children, and Department of Pediatrics, Department of Immunology, and Department of Medical Science, University of Toronto, and Cell Biology Program, the Hospital for Sick Children Research Institute; C. Bombardier, MD, MSc, Division of Clinical Decision Making and Health Care, Toronto General Research Institute, University Health Network, and the Department of Health Policy, Management and Evaluation, University of Toronto, and the Institute for Work and Health, and the Division of Rheumatology, Mount Sinai Hospital. Address correspondence to Dr. R. Berard, Children's Hospital, London Health Sciences Centre, 800 Commissioners Road East, London, Ontario N6A 5W9, Canada. E-mail: Roberta.berard@lhsc.on.ca. Accepted for publication August 6, - - 2014
To describe the trajectories of longitudinal joint disease activity in juvenile idiopathic arthritis (JIA), and to examine associations of clinical and laboratory characteristics with the identified trajectories. A retrospective cohort study at 2 Canadian centers was performed. The longitudinal trajectories of active joint counts were described in a proof-of-concept study ...
Corhay Jean - - 2014
BackgroundNeutrophils have been involved in the pathogenesis of chronic obstructive pulmonary disease (COPD). Underlying mechanisms of neutrophil accumulation in the airways of stable and exacerbated COPD patients are poorly understood. The aim of this study was to assess exhaled breath condensate (EBC) neutrophil chemotactic activity, the level of two chemoattractants ...
Jacobs Julia J Department of Neuropediatrics and Muscular Disease, University Medical Center Freiburg, Germany. Electronic address: - - 2014
High frequency oscillations (HFOs, 80-500Hz) are EEG biomarkers for epileptogenic areas. HFOs are also indicators of disease activity as HFO rates increase after reduction of antiepileptic medication. Electrical stimulation (ES) can be used for diagnostic purposes as well as therapy in patients with refractory epilepsy. This study investigates the occurrence ...
Sekeroglu Mehmet A MA *Ulucanlar Eye Training and Research Hospital †Department of Ophthalmology, Hacettepe University Faculty of Medicine, Ankara, - - 2014
To evaluate the hereditary thrombophilic factors in patients with primary open-angle glaucoma, exfoliative glaucoma, and exfoliation syndrome and to compare their results with those of healthy control subjects. The study included 75 patients [25 patients with primary open-angle glaucoma (group I), 25 patients with exfoliative glaucoma (group II), and 25 ...
Keeney James A JA Department of Orthopaedic Surgery, Washington University School of Medicine, 660 South Euclid, CB 8233, St Louis, MO, 63110, USA, - - 2014
Surgeons perform THA to address a variety of conditions in younger patients, including osteoarthritis (OA), osteonecrosis, inflammatory arthritis, and congenital deformities. Younger patients aged 50 years or younger have been characterized as active in the literature, but a direct relationship between age and activity level has not been well substantiated. Younger ...
Wang Grace Y GY Department of Psychology, Auckland University of Technology, New Zealand. Electronic address: - - 2014
This study investigated the electrophysiological activity associated with methadone maintenance treatment (MMT). The resting EEG spectrum of beta (14.5-30Hz), alpha (8-13Hz), theta (4-7.5Hz) and delta (1.5-3.5Hz) rhythm were measured in 32 patients undertaking chronic MMT, 17 opiate users and 25 healthy volunteers. Differences in the EEG components of each group ...
Iwamoto Takuya T Department of Pharmacy, Mie University Hospital, Tsu, Mie, 514-8507, Japan; Department of Clinical Pharmacy and Biopharmaceutics, Mie University Hospital, Tsu, Mie, 514-8507, - - 2014
Basophil activation was observed in patients with a history of carboplatin-induced severe hypersensitivity reaction. However, the precise mechanism by which carboplatin induces basophil activation and the associated surrogate markers remain to be elucidated. To investigate whether IgE-dependent mechanisms, including the overexpression of FcεRI, participate in carboplatin-induced basophil activation, thirteen ovarian ...
Halls Serena S Faculty of Health and Applied Sciences, University of the West of England, School of Clinical Sciences, University of Bristol and Rheumatology Department, Bristol Royal Infirmary, Bristol, UK. - - 2014
Stiffness is internationally recognized as an important indicator of inflammatory activity in RA but is poorly understood and difficult to measure. The aim of this study was to explore the experience of stiffness from the patient perspective. Semi-structured interviews conducted with 16 RA patients were analysed independently by researchers and ...
Yeo Sujung - - 2014
Acupuncture is increasingly used as an additional treatment for patients with Parkinson's disease (PD). In this functional magnetic resonance imaging study, brain activation in response to acupuncture in a group of 12 patients with PD was compared with a group of 12 healthy participants. Acupuncture was conducted on a specific ...
Fragoulis George E GE Department of Pathophysiology, School of Medicine, National and Kapodestrian University of Athens, - - 2014
Aberrant removal of necrotic debris is considered a feature with inflammatory consequences in SLE. Herein, primary Sjögren's syndrome (SS) patients were investigated for the first time for the capacity of their sera to degrade secondary necrotic cell remnants (SNEC) and DNA (endonuclease DNase1 activity), as well as for uptake of ...
Kostik Mikhail M MM Hospital Pediatry, Saint-Petersburg State Pediatric Medical University of Ministry of Healthcare of the Russia, 194100, Litovskaya 2, Saint-Petersburg, Russia. Electronic address: - - 2014
The purpose of our study was to detect early clinical and laboratory signs that help to discriminate macrophage activation syndrome (MAS) from active systemic juvenile idiopathic arthritis (SJIA) without MAS. Our retrospective study was based on reviewing the medical charts of the children admitted to the rheumatology department with active ...
Bounafaa Abdelghani A Laboratory of Biochemistry & Neuroscience, Applied Biochemistry and Toxicology Team, Hassan I University, Faculty of Sciences and Technology, Settat, Morocco; Department of Biology, Polydisciplinary Faculty, Sultan Moulay Sliman University, Beni-Mellal, Morocco; Laboratory of Biochemistry, Pasteur Institute of Morocco, Casablanca, Morocco; Department of Medicine, Geriatrics Service, Faculty of Medicine and Biological Sciences, University of Sherbrooke, Sherbrooke, Quebec, - - 2014
The functionality of HDL has been suggested as an important factor in the prevention of cardiovascular and coronary artery diseases. The objective of the present study was to investigate the functionality of HDL and the factors that may affect the anti-atherogenic properties of HDL in ACS patients. One hundred healthy ...
Hoirisch-Clapauch Silvia S Department of Hematology, Hospital Federal dos Servidores do Estado, Ministry of Health, Rio de Janeiro, Brazil. Electronic address: - - 2014
Clot buster tissue plasminogen activator (tPA) and its end-product plasmin play a well-defined role in neurochemistry. They mediate a number of events that culminate in tolerance against excitotoxicity, hippocampal neurogenesis, synaptic remodeling, neuronal plasticity, cognitive and emotional processing. Abnormalities in these processes have been implicated in schizophrenia pathogenesis. Laboratory markers ...
Søholm Helle H Department of Cardiology 2142, The Heart Center, Copenhagen University Hospital - - 2014
Out-of-hospital cardiac arrest (OHCA) is associated with a poor prognosis and predicting outcome is complex with neurophysiological testing and repeated clinical neurological examinations as key components of the assessment. In this study we examine the association between different electroencephalography (EEG) patterns and mortality in a clinical cohort of OHCA-patients. From ...
Magnusson Sofia E SE Department of Cell and Molecular Biology, Uppsala University, Uppsala, - - 2014
Given the critical role of Fc gamma receptors (FcγR) as primary targets for autoantibody-mediated effects an important issue is how the FcγR pathway is affected in autoimmune disorders. Here we investigated the FcγR function in monocytes from rheumatoid arthritis (RA) patients in relation to immunoglobulin levels and disease activity. Peripheral ...
Marrali Giuseppe G "Rita Levi Montalcini" Department of Neuroscience, ALS Centre, University of Torino, Via Cherasco 15, 10126, Turin, Italy, - - 2014
NADPH-oxidases (NOX) catalyze the formation of reactive oxygen species (ROS), which play a role in the development of neurological diseases, particularly those generated by the phagocytic isoform NOX2. Increased ROS has been observed in the amyotrophic lateral sclerosis (ALS) SOD1 transgenic mouse, and in this preclinical model the inactivation of ...
Ladino Lady D LD Department of Medicine, Division of Neurology, University of Saskatchewan, Saskatoon, Canada, Department of Neurology, Hospital Pablo Tobón Uribe, Medellín, - - 2014
Aim. Previous studies support the concept that obesity is a common comorbid condition in patients with epilepsy (PWE). In this study, we present the body mass index (BMI) and data from a survey to assess physical activity in a sample of PWE from an epilepsy clinic. Methods. Between June of ...
Voiosu Theodor T Colentina Clinical Hospital; Carol Davila University of Medicine and Pharmacy, Bucharest, Romania. - - 2014
Mucosal healing is an important predictor of disease-related outcome in patients with inflammatory bowel disease (IBD) patients, including those in clinical remission. However, colonoscopy is an invasive procedure and many patients decline repeated endoscopic examinations. We aimed to assess whether noninvasive biomarkers could accurately detect endoscopic mucosal inflammatory activity in ...
Wang Yong Y 1Department of Experimental Cardiology, Excellence Cluster Cardio-Pulmonary System, Justus-Liebig University Giessen, Germany; 2Department of Internal Medicine, UFMG, Belo Horizonte, Brazil; 3Instituto Metropolitano de Ensino Superior (IMES)/Univaço, Ipatinga, Brazil; 4Department of Cardiology, Charité, Campus Benjamin Franklin, Berlin, Germany; 5Leibniz-Institute of Molecular Pharmacology, Berlin, Germany; 6Department of Physics, Humboldt Universität zu Berlin, Berlin, Germany; 7Department of Pharmacology and Therapeutics, University College Cork, Cork, Ireland; 8Department of Pediatric Surgery, Division of Women and Child Health, University of Leipzig, 04103 Leipzig, - - 2014
Plasma angiotensin-converting enzyme (ACE) 2 activity has been demonstrated to be an independent prognostic marker in Chagas' disease (CD), equally potent as B-type natriuretic peptide. This study aims to investigate the prognostic potency of circulating ACE2 activity in patients with idiopathic dilated cardiomyopathy (DCM).Blood samples were withdrawn from patients with ...
Liu Qing Q Department of Special Care Center, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, - - 2014
Red blood cell distribution width (RDW) has been shown to be related to both anemia and inflammation in various diseases. However, the role of RDW in patients with Takayasu arteritis (TA) is unknown. Therefore, we investigated the association of RDW with anemia, inflammation, and disease activity in TA. RDW was ...
Tong Wing H WH Erasmus Medical Center, The - - 2014
We prospectively studied the incidence and clinical course of hypertriglyceridemia and hypercholesterolemia during very prolonged use of asparaginase or in relation to asparaginase activity levels in children with acute lymphoblastic leukemia. Also, incidence of pancreatitis, thrombosis, hyperammonemia and central neurotoxicity and their association with asparaginase activity levels were evaluated. 89 ...
Thaler Johannes J Clinical Division of Haematology and Haemostaseology, Department of Medicine I, Medical University of Vienna, - - 2014
Tissue factor (TF) is the main in-vivo initiator of blood coagulation. Microparticles (MPs) are small procoagulant membrane vesicles. Elevated TF-bearing MPs have been found in different prothrombotic conditions and MP-associated TF activity may contribute to the pathogenesis of unprovoked deep vein thrombosis (DVT). To determine MP-TF activity levels at diagnosis ...
Connolly Mark M Department of Neurosurgery, David Geffen School of Medicine, University of California, Los Angeles, CA, - - 2014
The objective of this study is to characterize the relationship between ICP and EEG METHODS: Simultaneous ICP and EEG data were obtained from burst-suppressed patients and segmented by EEG bursts. Segments were categorized as increasing/decreasing and peak/valley to investigate relationship between ICP changes and EEG burst duration. A generalized ICP ...
Yılmaz Bülent B Bülent Yılmaz, Seyfettin Köklü, Osman Yüksel, Serap Arslan, Department of Gastroenterology, Faculty of Medicine, Hacettepe University, Sihhiye, 06100 - - 2014
To investigate the diagnostic utility of beta 2 microglobulin (B2-M) levels and analyze this correlation with the activity of inflammatory bowel disease (IBD). Overall, 78 IBD patients and 30 healthy controls were enrolled in the study. We examined B2-M serum levels in 43 ulcerative colitis (UC) patients, 35 with Crohn's ...
Zahm Adam M AM Children's Hospital of - - 2014
The incidence of eosinophilic esophagitis has increased in the past several years, yet our understanding of pathogenesis remains limited. To test the hypothesis that microRNAs are altered in children with eosinophilic esophagitis, microRNAs were profiled in esophageal mucosa biopsies obtained from patients with active disease (n=5) and healthy control subjects ...
Della-Torre Emanuel E Massachusetts General Hospital Cancer Center, Boston, Massachusetts, USA Unit of Medicine and Clinical Immunology, IRCCS-San Raffaele Scientific Institute, Università Vita-Salute San Raffaele, Milan, - - 2014
Fibrosis is a predominant feature of IgG4-related disease (IgG4-RD). B-cell depletion induces a prompt clinical and immunological response in patients with IgG4-RD, but the effects of this intervention on fibrosis in IgG4-RD are unknown. We used the enhanced liver fibrosis (ELF) score to address the impact of rituximab on fibroblast ...
Knaś Małgorzata - - 2014
However, there are some informations on the salivary glands involvement in systemic sclerosis, and there is a lack of any data about salivary glands function depending on systemic sclerosis subsets. The unstimulated and stimulated salivary flow, the activity of peroxidase, the total amount of lactoferrin, lysozyme and sIgA were determined ...
Adlan Ahmed M AM College of Life and Environmental Sciences, University of Birmingham, Edgbaston, Birmingham B15 2 TT, UK. Electronic address: - - 2014
Rheumatoid arthritis (RA) is a chronic inflammatory condition with increased all-cause and cardiovascular mortality. Accumulating evidence indicates that the immune and autonomic nervous systems (ANS) are major contributors to the pathogenesis of cardiovascular disease. We performed the first systematic literature review to determine the prevalence and nature of ANS dysfunction ...
Ehab A M AM Faculty of Applied Medical Science in AL Qurayyat, Clinical laboratory Sciences, Aljouf University, Saudi - - 2014
Hematological malignancies can change the levels of plasma molecules involved in coagulation and fibrinolysis such as fibrinopeptide A, fibrinogen, plasminogen activator inhibitor-1 (PAI-1) and D-dimer, markers of endothelial cell integrity (soluble E-selectin, van Willebrand factor and soluble thromboembolism) and of platelet function (beta-thromboglobulin). The aim of this study was to ...
Kragelund C C Section of Oral Medicine, Clinical Oral Physiology, Oral Pathology & Anatomy, Department of Odontology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark. Electronic address: - - 2014
This study aimed to determine if the activity of the environmentally influenced cytochrome P450 enzyme CYP1A2, alone or in combination with CYP2D6*4 genotype, discriminates subgroups of oral lichen planus (OLP) according to lifestyle factors and clinical manifestations. A total of 111 patients with OLP were categorized according to normal, low, ...
Mirpourian Maryam M Department of Internal Medicine, Isfahan University of Medical Sciences, Isfahan, - - 2014
The role of obesity in clinical curse of rheumatoid arthritis (RA) is not clear. We investigated the association of obesity and adiposity with disease activity and clinical response to combination therapy in RA patients. Active RA patients with the disease activity score using 28 joint counts (DAS28) > 2.6 were ...
Lehmann Dietrich D Department of Psychiatry, Psychotherapy and Psychosomatics, The KEY Institute for Brain-Mind Research, University Hospital for Psychiatry Zurich, - - 2014
Functional dissociation between brain processes is widely hypothesized to account for aberrations of thought and emotions in schizophrenic patients. The typically small groups of analyzed schizophrenic patients yielded different neurophysiological findings, probably because small patient groups are likely to comprise different schizophrenia subtypes. We analyzed multichannel eyes-closed resting EEG from ...
Keles Sadullah S Department of Ophthalmology, School of Medicine, Ataturk University, Erzurum, - - 2014
To evaluate levels of homocysteine, asymmetric dimethylarginine (ADMA), and nitric oxide (NO), as well as activity of endothelial NO synthase (eNOS), in patients with age-related macular degeneration (AMD). The levels of homocysteine, ADMA, and NO and activity of eNOS in patients who were diagnosed with wet AMD by fundus fluorescein ...
Tsurumi Kosuke K Department of Psychiatry, Kyoto University Graduate School of Medicine Kyoto, - - 2014
Pathological gambling (PG) is a chronic mental disorder characterized by a difficulty restraining gambling behavior despite negative consequences. Although brain abnormalities in patients with substance use disorders are caused by repetitive drug use and recover partly with drug abstinence, the relationship between brain activity and duration of illness or abstinence ...
Godfrin-Valnet Marie M Department of Rheumatology, Centre Hospitalier Régional Universitaire (CHRU) Besançon, Besançon, - - 2014
Background Sirtuin 1 (SIRT1) is a class III histone deacetylase that may play a critical role in several biological functions, including lifespan, stress, and inflammation. Our main objective was to evaluate SIRT1 activity in peripheral blood mononuclear cells (PBMCs) in patients with osteoporosis and to analyze the relationship between the ...
Demir Gülseren G Ankara Training and Research Hospital, Clinic of Physical Medicine and - - 2014
Serum adenosine deaminase (ADA) has been previously proposed to predict disease activity in patients with rheumatoid arthritis (RA). The aim of this study was to investigate the level of serum ADA, and the relationship between ADA and disease activity markers, in a group of patients with RA. A hundred and ...
Milnerowicz Halina H Department of Biomedical and Environmental Analysis, Medical University of Wroclaw, Borowska 211, 50-556 Wroclaw, - - 2014
Oxidative stress and inflammatory mediators, such as IL-6, play an important role in the pathophysiology of acute pancreatitis. The study was aimed to assess the degree of the pro/antioxidative imbalance and estimate which antioxidant plays a role in the maintenance of pro/antioxidative balance during acute pancreatitis. The study was investigated ...
Horan William P WP VA Greater Los Angeles Healthcare System, Los Angeles, California, United States of America; University of California Los Angeles, Los Angeles, California, United States of - - 2014
Although motivational disturbances are common in schizophrenia, their neurophysiological and psychological basis is poorly understood. This electroencephalography (EEG) study examined the well-established motivational direction model of asymmetric frontal brain activity in schizophrenia. According to this model, relative left frontal activity in the resting EEG reflects enhanced approach motivation tendencies, whereas ...
Hashiguchi Keiichi K Department of Gastroenterology and Hepatology, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, - - 2014
Background Bamboo joint-like appearance is a common yet easy-to-miss endoscopic finding in the stomach of patients with Crohn's disease (CD). Bamboo joint-like appearance (BJA) is characterized by swollen longitudinal folds transversed by erosive fissures or linear furrows. However, whether BJA is observed during the remission stage of CD and during ...
Yılmaz Ünsal - - 2012
Matrix metalloproteinases and their tissue inhibitors play a key role in the pathogenesis of adult-onset multiple sclerosis, and were suggested as biomarkers of response to interferon-β, an established treatment in multiple sclerosis. However, data regarding pediatric population are scarce. We determined serum levels of matrix metalloproteinase-7, matrix metalloproteinase-9, and tissue ...
Chen Yung-Tai - - 2012
ABSTRACT: BACKGROUND: The renin-angiotensin-aldosterone system (RAAS) plays an important role in the progression of chronic kidney disease (CKD). Although dual RAAS inhibition results in worse renal outcomes than monotherapy in high risk type 2 diabetes patients, the effect of dual RAAS inhibition in patients with non-DM CKD is unclear. The ...
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