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Results 451 - 500 of 1262
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Chow Kai Ming - - 2008
OBJECTIVES: Several studies have examined the possible association between late referral to a nephrologist and mortality on maintenance hemodialysis. However, we lack information on the benefit of early nephrologist referral in patients receiving peritoneal dialysis (PD). PATIENTS AND METHODS: In an inception cohort of 102 consecutive PD patients identified in ...
Carson Shannon S - - 2008
A measure that identifies patients who are at high risk of mortality after prolonged ventilation will help physicians communicate prognoses to patients or surrogate decision makers. Our objective was to develop and validate a prognostic model for 1-yr mortality in patients ventilated for 21 days or more. The authors conducted ...
Valli Alessandro - - 2008
OBJECTIVE: The putative role of sulfur amino acids such as homocysteine (tHcy) as cardiovascular risk factors is controversial in chronic kidney disease (CKD). Although, S-adenosylhomocysteine (SAH) levels have been linked to CVD in non-renal populations, such relationship has not been evaluated in CKD. DESIGN: Serum concentrations of S-adenosylmethionine (SAM), SAH ...
Migliacci Rino - - 2008
BACKGROUND: The ankle-brachial index (ABI), i.e. the ratio of the ankle to brachial systolic blood pressure, is the golden standard for the diagnosis of peripheral arterial disease (PAD) and is a highly specific method for the assessment of vascular risk in otherwise asymptomatic patients. OBJECTIVE: To assess the diagnostic accuracy ...
Chih Sharon - - 2008
BACKGROUND: Abnormal glucose regulation (AGR) is common and an adverse risk factor in patients presenting with acute coronary syndromes (ACS). METHODS: We prospectively evaluated the prevalence of AGR in 300 ACS patients. Fasting blood glucose (BGL), glycated haemoglobin (HbA1c) and urinary albumin creatinine ratio (ACR) were performed. Patients without diabetes ...
Chan Y C - - 2008
Marfan syndrome is a connective tissue disorder with a worldwide prevalence of 1 in 5,000, without any racial predilection. Major cardiovascular manifestations of Marfan disease often require surgical intervention. The aim of this study was to examine the demographics of patients with Marfan syndrome admitted to Hong Kong hospitals over ...
Uthoff H - - 2008
PURPOSE: Intima-media thickness (IMT) of the common carotid artery and the resistive index (RI) of the internal carotid artery correlate with the degree of atherosclerosis and are predictors of cardiovascular morbidity and mortality. Limited or no data are available about long-term predictive values and the progression of the two markers ...
Vinker Shlomo - - 2008
OBJECTIVE: To describe adherence with statin treatment in a usual practice setting and to investigate potential determinants of better adherence. STUDY DESIGN: Retrospective cohort study using administrative claims data. METHODS: Study patients were 47,680 individuals enrolled in the Central District of Clalit Health Services HMO in Israel who filled at ...
de Boccardo G - - 2008
BACKGROUND: Chronic kidney disease (CKD) is an important risk factor for morbidity and mortality post-liver transplantation (OLT). This study focused on investigating the incidence and risk factors associated with the development CKD after OLT. METHODS: We performed a retrospective cohort study of recipients followed at least 5 years at our ...
Cooper Howard A - - 2008
OBJECTIVE: Cardiovascular disease has a tremendous impact on patients with end-stage renal disease (ESRD). We sought to describe the outcomes of patients with ESRD and acute myocardial infarction (AMI). METHODS: We analyzed consecutive AMI patients admitted to a single coronary care unit, according to the presence or absence of ESRD. ...
Klima Theresia - - 2008
Body temperature (BT) was shown to have impact on outcome in several medical conditions. This study investigated the prognostic impact of BT in patients with acute heart failure (HF). The B-type natriuretic peptide for Acute Shortness of breath EvaLuation (BASEL) study prospectively enrolled 452 consecutive patients presenting with acute dyspnoea ...
Tsuiki Mika - - 2008
Although subclinical Cushing's syndrome has been commonly experienced, details of the clinical outcome and its indication for adrenalectomy have yet to be established. In the present study, we investigated the prevalence of cardiovascular risks, their clinical outcome during long-term follow up before and after adrenalectomy in 20 patients with subclinical ...
Tajima Naoko - - 2008
Diabetes mellitus (DM) is a major risk factor for cardiovascular disease (CVD) in patients with no history of CVD. Evidence for the effect of statins on CVD in the diabetic population in low-risk populations (e.g., Japanese) is limited. We evaluated the effect of pravastatin on risk reduction of CVD related ...
Tousoulis Dimitris - - 2008
BACKGROUND: Major depression (MD) is a key feature in heart failure (HF), and it is unclear whether common antidepressive medications interact with cardiovascular drugs used for the treatment of patients with MD and HF, affecting their efficacy. We examined the impact of MD on long-term survival of patients with end-stage ...
Sangle S R - - 2008
OBJECTIVE: Cardiovascular disease may be increased in patients with systemic vasculitides (SV). The Ankle-Brachial Pressure Index (ABPI) is a non-invasive tool for the assessment of cardiovascular risk (CV). Our aim was to determine the prevalence of an abnormal ABPI in patients with SV and healthy controls and to correlate with ...
Aakre Jennifer M - - 2009
Many studies have found that people experiencing persecutory delusions have a marked tendency to use external-personal attributions when establishing the causes of negative events. Although nonclinical populations also tend to attribute negative events to external causes, those causes are typically believed to be universal in nature, rather than personal. The ...
Chang Sung-A - - 2008
BACKGROUND: Recently, multidetector computed tomography (MDCT) has been proposed as an accurate diagnostic tool to evaluate for coronary artery disease. However, the role of MDCT as part of the initial diagnostic for evaluating acute chest pain is less well established. METHODS: We prospectively enrolled patients presenting with acute chest pain ...
Cook Jeffrey R - - 2008
Chronic kidney disease (CKD) and anemia portend a higher risk of cardiac events and mortality. We sought to ascertain whether coronary artery disease (CAD) by myocardial perfusion single-photon emission computed tomography is more common in patients with CKD (glomerular filtration rate < or =60 ml/min/1.73 kg/m(2)) and/or anemia (hemoglobin level ...
Yeo Tiong Cheng - - 2008
INTRODUCTION: Atherothrombosis is the leading cause of cardiovascular mortality. The Reduction of Atherothrombosis for Continued Health (REACH) Registry provided information on atherosclerosis risk factors and treatment. Singapore was one of the 44 participating countries in the REACH Registry. The objective of this study was to determine the atherosclerosis risk factor ...
Jerng Jih-Shuin - - 2008
BACKGROUND: The prognosis of in-hospital cardiopulmonary arrest remains very poor. Reports have shown patients often have clinically abnormal events prior to arrest. To improve patient outcome and prevent arrest, detection of the abnormal events with early intervention has been advocated. However, the incidence of these events in Taiwan and their ...
Denollet Johan - - 2008
OBJECTIVE: Coronary artery disease (CAD) patients who report low distress are considered to be at low psychological risk for clinical events. However, patients with a repressive coping style may fail to detect and report signals of emotional distress. The authors hypothesized that repressive CAD patients are at risk for clinical ...
Reintam Annika - - 2008
OBJECTIVE: To investigate the differences in incidence, time course and outcome of primary versus secondary intra-abdominal hypertension (IAH), and to evaluate IAH as an independent risk factor of mortality in a presumable risk population of critically ill patients. DESIGN: Prospective observational study. SETTING: General intensive care unit of a university ...
Scalzi Lisabeth V - - 2008
OBJECTIVE: Cardiovascular disease (CVD) is a major cause of morbidity and mortality in systemic lupus erythematosus (SLE) patients. The aim of this study was to identify factors associated with patients' recognition of SLE as an independent risk factor for CVD and their perception of their personal CVD risk. METHODS: SLE ...
Rehak Matus - - 2008
Several small case-control studies have investigated whether factor V Leiden (FVL) is a risk factor for retinal vein occlusion (RVO) and generated conflicting data. To clarify this question we performed a large two-centre case-control study and a meta-analysis of published studies. Two hundred seven consecutive patients with RVO and a ...
Stone William M - - 2008
The risk of cerebrovascular events in patients with mild to moderate peripheral vascular disease is significant. Cilostazol is a phosphodiesterase type 3 (PDE3) inhibitor that is effective in the treatment of symptoms of peripheral arterial occlusive disease. The method of action includes antithrombotic, vasodilatory, and antiproliferative effects. The Cilostazol: A ...
Song Zhi - - 2008
A number of clinical trials have examined whether antibiotics decrease the incidence of adverse events in patients with cardiovascular diseases. However, results have occasionally been conflicting, and a meta-analysis may provide additional clarification. To address whether antibiotic use can reduce the risk of future cardiac events among patients with established ...
Rothberg Michael B - - 2008
Chronic kidney disease (CKD) is a growing problem among the elderly. Early detection is considered essential to ensure proper treatment and to avoid drug toxicity, but detection is challenging because elderly patients with CKD often have normal serum creatinine levels. We hypothesized that most cases of CKD in the elderly ...
Kamber Niklaus - - 2008
OBJECTIVE: To determine the incidence of lactic acidosis in community-based patients with type 2 diabetes, with special reference to metformin therapy. DESIGN: Substudy within a longitudinal observational study, the Fremantle Diabetes Study (FDS). PARTICIPANTS AND SETTING: 1279 patients from a postcode-defined population of 120 097 people in Western Australia. MAIN ...
Kellett John - - 2008
BACKGROUND: Predictive scores such as APACHE II have been used to assess patients in intensive care units, but few scores have been used to assess acutely ill general medical patients. DESIGN: Examination of the ability of clinical variables documented at the time of admission to predict early mortality between 15 ...
Pfeffer Marc A - - 2008
Epidemiologic observations showing associations between higher levels of some biologic markers such as blood pressure and serum cholesterol with heightened risk of death and non-fatal cardiovascular events have provided important data to develop hypotheses regarding pharmacologic therapies to modify these markers to improve prognosis. Randomized controlled trials have shown that ...
Cauthen Clay A - - 2008
Patients with chronic kidney disease and heart failure (HF) have been shown to be at higher risk for major adverse cardiovascular events and death. Recent studies have demonstrated that blood urea nitrogen (BUN) might serve as a powerful predictor of mortality in acutely decompensated HF. The goal of this study ...
Overgaard Christopher B - - 2008
BACKGROUND: Thrombocytopenia (TP) is a common baseline abnormality in patients undergoing percutaneous coronary intervention (PCI). Whether TP has any influence on the outcome of PCI patients is unknown. Our aim was to determine if TP at baseline impacts on inhospital mortality in patients undergoing PCI at our institution. METHODS: From ...
López-Jiménez Luciano - - 2008
There is little information on the effectiveness of secondary prevention interventions in very elderly patients. In this article, the incidence of major cardiovascular events during a 12-month follow-up period in a series of consecutive patients with coronary, cerebrovascular, or peripheral artery disease is analyzed. As of October 2006, 1264 patients ...
De Waele Jan J - - 2008
BACKGROUND: Blood stream infections (BSI) of abdominal origin are associated with a high mortality rate. We hypothesized that both patient and microbiological factors determine death in critically ill patients who develop such infections. METHODS: Ninety-six consecutive patients who developed BSI of abdominal origin in an 11-year period (1992-2002) in the ...
Barros Mário Henrique M - - 2008
BACKGROUND: A risk group (RG) system to predict bone marrow involvement (BMI) based on clinical and laboratory parameters was previously shown to have prognostic value in adult patients with Hodgkin lymphoma (HL). Our aim was to test the applicability of BMI RG in an independent group of childhood and adolescent ...
Wish J B - - 2008
AIMS: Anemia and cardiovascular (CV) events are major complications of chronic kidney disease (CKD) during dialysis. We conducted a retrospective observational study in CKD patients with anemia to evaluate the association between predialysis use of erythropoiesis-stimulating agents (ESAs) and postdialysis CV outcomes. METHODS: The study analyzed claims data on incident ...
Park Jai-Wun - - 2008
OBJECTIVE: Magnetocardiography (MCG) as a noninvasive, noncontact and risk-free diagnostic method predicts ischemic coronary artery disease (CAD) in patients with acute chest pain at admission with high accuracy. However, it remains unclear whether MCG findings can add prognostic information. METHOD: A cohort of 402 consecutive patients presenting at the intensive ...
Kosuge Masami - - 2008
BACKGROUND: The impact of body mass index (BMI) on outcomes after primary percutaneous coronary intervention (PCI) for acute myocardial infarction (AMI) remains unclear. METHODS AND RESULTS: A total of 3,076 patients undergoing PCI for AMI within 48 h after symptom onset were studied. Patients were divided into 4 groups according ...
Iqbal Mobeen - - 2008
Hypocalcemia has been a common abnormality in the West, seen in patients admitted to the intensive care unit (ICU). It has also been linked with disease severity. We undertook this study to determine the frequency of hypocalcemia in patients admitted to the intensive care unit. In a retrospective chart review ...
Unalp H R HR General Surgery Clinic, Ataturk Training and Research Hospital, Izmir, Turkey. - - 2008
Fournier's gangrene (FG) is a rapidly progressing acute gangrenous infection of the anorectal and urogenital area. The objectives of this study were to investigate patients with FG and to determine risk factors that affect mortality. Retrospective clinical study. Clinical presentations and outcomes of surgical treatments were evaluated in 68 patients ...
Tsai Shih-Hung - - 2008
BACKGROUND: Diabetes mellitus (DM) is associated with adverse events or complications in various gastrointestinal diseases. In this study, we examined whether diabetic patients had higher risk for the development of complicated acute appendicitis than nondiabetic patients. The relevant risk factors also were determined. METHODS: A retrospective study enrolling diabetic and ...
Rueda Sergio F - - 2009
OBJECTIVE: The aim of this study was to describe the prevalence of cardiovascular disease risk factors (CVDRFs) and the degree of control in a Spanish population of patients with type 1 diabetes (DM1) and end-stage renal disease (ESRD) as well as the changes observed in this setting over 8 years. ...
Wang Tracy Y - - 2008
AIMS: To examine treatment patterns and outcomes of patients with non-ST-segment elevation acute coronary syndrome (NSTE ACS) receiving long-term warfarin anticoagulation. METHODS AND RESULTS: We examined acute medication and invasive cardiac procedure use and in-hospital outcomes among 101,078 patients with NSTE ACS included in the CRUSADE registry. On admission, 7201 ...
Dunkelgrun M - - 2009
BACKGROUND: Hyperhomocysteinaemia is independently associated with atherosclerotic disease. Methionine loading could improve the predictive value of hyperhomocysteinaemia by detecting mild disturbances in enzyme activity. The aims of this study were to determine the beneficial effect of methionine loading on the predictive value of homocysteine testing for long-term mortality and major ...
Sari Ali B A AB Department of Health Economics and Management, Tehran University of Medical Sciences, Poursina Ave, Tehran 1417613191, Iran. - - 2008
to estimate the extent, preventability and consequences of adverse clinical events in elderly and non-elderly patients. a two-stage structured, retrospective, patient case-note review. a large NHS hospital in England. a random sample of 1,006 non-psychiatric patients. proportion of patients with adverse events, the proportion of preventable adverse events and the ...
Barsheshet Alon - - 2008
A widened QRS interval is associated with increased mortality in patients with heart failure (HF). However, the prognostic significance of the type of bundle branch block (BBB) pattern in these patients is unclear. The data of 4,102 patients with HF hospitalized during a prospective national survey were analyzed to investigate ...
Wright D M - - 2008
In this prospective study, 230 patients who were operated on for a fractured neck of femur were evaluated using the physiological and operative severity score for the enumeration of mortality and morbidity (POSSUM). We observed 25 deaths (10.9%) and 95 patients had a post-operative complication (41.3%). The orthopaedic POSSUM equations ...
Yeo Khung Keong - - 2008
Guidelines published by the National Kidney Foundation in 2002 categorize renal failure into 5 stages of increasing severity. The relation of this classification to risk stratification for operative mortality in patients with nonemergent coronary artery bypass grafting (CABG) has not been clarified. We examined the effect of chronic kidney disease ...
Cardarelli Francesca - - 2008
BACKGROUND: Chronic kidney disease (CKD) is a predictor of morbidity and mortality in patients undergoing percutaneous coronary interventions (PCIs), and African American (AA) patients have been reported to have worse outcomes after PCI. METHODS: We assessed whether CKD affects the rate of death and major adverse cardiovascular events (MACE = ...
Kapoor Rachna - - 2008
PURPOSE: Two instruments for assessing patients' risk of postoperative nausea and vomiting (PONV) were compared. METHODS: The existing protocol (protocol 1) assessed PONV risk using 16 weighted risk factors and was used for both adults and pediatric patients. The new protocol (protocol 2) included a form for adults and a ...
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