Search Results
Results 351 - 400 of 1000
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Gazzard Gus - - 2003
PURPOSE: To assess the prevalence of optic disc hemorrhage in Asian patients with established glaucoma using a recently described, highly sensitive detection method. MATERIALS AND METHODS: Patients entering a trial of glaucoma filtering surgery in Southeast Asia (The Singapore 5FU Study) were assessed for the presence or absence of optic ...
Vidaurri-de la Cruz Helena - - 2003
Nearly 200 cases of phakomatosis pigmentovascularis (PPV) have been reported worldwide, most of them of Japanese origin. There are 5 types and 10 subtypes of PPV. Its etiology might be explained by the twin spotting phenomenon. The relative frequency of PPV at the National Institute of Pediatrics was 5.8 per ...
Christen R - - 2003
PURPOSE: To examine the incidence and pattern of iris transillumination defects in patients with primary open angle glaucoma (POAG) with and without vascular dysregulation, in comparison to controls. METHODS: We prospectively examined 24 patients with POAG (M/F 10:14; mean age 59 +/- 14, range 21-76 years) and 23 controls (M/F ...
Eiseman Andrew S - - 2003
PURPOSE: To determine the prevalence rates and associated characteristics of patients who have ocular surface, ocular adnexal, and lacrimal complications associated with the systemic use of the cancer chemotherapeutic agent 5-Fluorouracil (5-FU). METHODS: An exposure-based cohort study was designed. Adult patients who had completed at least 3 months of systemic ...
Kotaniemi K - - 2003
OBJECTIVE: To look for forme fruste (incomplete) forms of juvenile idiopathic arthritis (JIA)-associated uveitis. METHODS: The study involved 6 patients (3 girls and 3 boys) without overt arthritis who had been sent for ophthalmologic and rheumatologic evaluation because of uveitis resembling that seen in JIA. RESULTS: Two patients evinced no ...
Baltatzis Stefanos - - 2003
To evaluate the outcomes of patients with chronic ocular inflammatory disease treated with mycophenolate mofetil as an immunosuppressive and steroid-sparing agent. Retrospective noncomparative interventional case series. All patients with ocular inflammatory disease treated with mycophenolate mofetil at a single institution between 1998 and 2001. Charts of patients seen on the ...
Bang Dong Sik - - 2003
Behçet's disease (BD) is a multisystemic inflammatory disorder known as having a histopathological findings of vasculitis. The influence of sexual difference on BD is a well-known fact and there are several reports suggesting a more severe course of the disease among young males. The purpose of our study was to ...
Shah Chirag - - 2003
Therapeutic soft contact lenses were first approved in the 1970s, but the variety of available materials and parameters continues to evolve. Currently, the armamentarium of therapeutic contact lenses allows the clinician to select lenses that not only protect the corneal surface but also assist in modulation of the healing process. ...
Koliakos G G - - 2003
The authors investigated the concentrations of 8-isoprostaglandin F(2a), a marker of oxidative stress in vivo, and ascorbic acid, a protectant against oxidative damage, in the aqueous humour of patients with exfoliation syndrome (XFS) and cataract and compared the results with those in age matched patients with cataract, but without XFS, ...
Franke Sybille - - 2003
PURPOSE: To investigate whether the advanced glycation end-products (AGEs) pentosidine, N( epsilon )-(carboxymethyl)lysine (CML), and imidazolone are present in the aqueous of cataract patients and how AGE levels correlate to cataract type or the diabetic condition of the patient. SETTING: Departments of Ophthalmology and Internal Medicine, University of Jena, Jena, ...
Leibovitch Igal - - 2003
PURPOSE: To determine the prevalence of hyperhomocystinemia in patients with pseudoexfoliation glaucoma. PATIENTS AND METHODS: This prospective study included 30 patients with glaucoma and 30 age-matched controls with no history of ocular disease who were undergoing routine physical checkups. Plasma homocysteine levels of all the study participants were determined using ...
Thomas Ravi - - 2003
PURPOSE: To determine the prevalence of glaucoma in a population of patients with multibacillary Hansen disease who had completed treatment. PATIENTS AND METHODS: The authors examined 386 of 446 patients with treated multibacillary Hansen disease residing in a geographically limited area. A complete ophthalmic examination including slit-lamp, applanation tonometry, gonioscopy, ...
Batchelor Tracy T - - 2003
PURPOSE: Intraocular lymphoma (IOL) frequently coexists with primary central nervous system lymphoma(PCNSL). We sought to determine the efficacy of high-dose methotrexate (MTX) alone in patients with IOL. We also sought to determine whether micromolar levels of MTX could be achieved in the aqueous and vitreous humor of the eye after ...
Medeiros Felipe A - - 2003
PURPOSE: It has been suggested that a considerable subset of patients currently classified as having ocular hypertension may have thicker than average corneas that result in an overestimation of the true intraocular pressure (IOP). As a consequence, ocular hypertension patients with greater corneal thickness may be at a lower risk ...
Mashima Yukihiko - - 2003
BACKGROUND: Abnormal optic disc excavations are reportedly seen in patients with Leber's hereditary optic neuropathy (LHON), a mitochondrial dysfunction disease. We examined the disc morphology in the eyes of patients with LHON at the atrophic stage and compared it to that in eyes with normal-tension glaucoma (NTG). METHODS: We studied ...
Tanaka Takao - - 2003
BACKGROUND: Glucocorticoids (GC) are widely used to treat uveitis, but their efficacy is known to vary substantially among patients. In this retrospective preliminary study, we measured the level of GC receptor (GCR) expression in ocular tissue taken from uveitis patients during cataract surgery as an indicator of their sensitivity to ...
McCulley James P - - 2003
PURPOSE: To characterize patients with ocular surface drying and a diagnosis of keratoconjunctivitis sicca (KCS). METHODS: Patients with a prior diagnosis of KCS and symptoms of dryness or foreign-body sensation who also had vital staining of the interpalpebral fissure ocular surface in the absence of lid and ocular surface inflammation ...
Buchan J - - 2003
AIM: Previous surveys of ocular disease in leukaemia patients have shown the retina, choroid, and orbit as the most commonly involved sites. Depending on the type of leukaemia and the study design, the prevalence of ocular disease in leukaemia varies from 30 to 90%. Although chronic lymphocytic leukaemia (CLL) is ...
Abelson Mark B - - 2003
This month-long multicenter, open-label study evaluated the onset and progression of hyperemia associated with bimatoprost 0.03% once daily in 39 patients with open-angle glaucoma or ocular hypertension. Current glaucoma medication(s) was either replaced with or augmented by bimatoprost. Previous users of bimatoprost were excluded. Primary outcome measures were mean hyperemia ...
Singh P - - 2003
Fifty patients of contact vitiligo were studied. Etiological agents of contact vitiligo were identified by clinical history, distribution of lesions and patch testing with suspected material. All patients were advised to avoid the suspected agent and treated with PUVASOL and topical steroid. Out of 50 patients (Male 8%, Female 92% ...
Khawam Edward - - 2003
BACKGROUND AND PURPOSE: To review the multiple factors in intermittent exotropia (X(T)) responsible for the discrepancy between the distance and near deviations; to challenge the classification of X(T) into types according to the two standard clinical tests of occlusion of one eye and the use of +3.00 D spherical lenses ...
Camara Jorge G - - 2002
OBJECTIVE: To describe a new physical finding called involutional lateral entropion (ILE) of the upper eyelid found in Asian patients. METHODS: A prospective case series study of 53 consecutive patients with ILE of the upper eyelid, from the practice of one of the authors (J.G.C.), was performed. All of the ...
Graul Thomas A - - 2002
PURPOSE: To determine whether primary open-angle glaucoma (POAG) and ocular hypertensive (OHT) patients who harbor the myocilin Gln368Stop mutation differ in phenotype or clinical course from patients without the mutation. DESIGN: Case-control study. METHODS: A retrospective case-control study compared all known POAG patients (n = 18) and OHT patients (n ...
Demirci Hakan - - 2002
BACKGROUND: Ring melanoma of the ciliary body is a rare variant of uveal melanoma that has a poor prognosis. Only isolated cases have been reported in the literature. METHODS: A retrospective review of the clinical features, management, histopathology, and prognosis of 23 consecutive patients with ring melanoma of the ciliary ...
Grødum Kirsti - - 2002
PURPOSE: To study differences between glaucoma patients identified through a population screening and glaucoma patients diagnosed in routine clinical practice (self-selected patients). METHODS: A total of 402 individuals with newly detected open-angle glaucoma were identified through a large population screening programme that ran from October 1992 to January 1997. The ...
Okka Mehmet - - 2002
BACKGROUND: Behçet's disease is a chronic relapsing systemic vasculitis of unknown origin in which orogenital ulceration, skin lesions and uveitis are prominent features. Patients with BD have been recognized to be at greater risk for vascular diseases such as thrombosis and aneurysms. Uveitis in BD is usually accompanied by retinal ...
Kim J H - - 2002
To identify the characteristic ocular findings in Asian children with Down syndrome. A total of 123 Korean children with Down's syndrome between 6 months and 14 years of age were examined for ocular findings from March 1999 to April 2000. Ocular examinations including visual acuity assessment, slit-lamp biomicroscopy, ocular motility, ...
Gündüz Abuzer - - 2002
PURPOSE: To evaluate whether an abnormal optic disc shape in patients with tilted disc syndrome (TDS) is associated with an abnormal configuration of the crystalline lens measured as lenticular astigmatism. SETTING: Department of Ophthalmology, Inönü University Medical Faculty, Turgut Ozal Medical Center, Malatya, Turkey. METHODS: This cross-sectional masked case-control study ...
Sanchez-Burson Juan - - 2002
OBJECTIVE: To examine immunogenetic and clinical features in a series of patients with the idiopathic tubulointerstitial nephritis and uveitis (TINU) syndrome diagnosed at the single referral hospital for a defined population in Southern Spain. PATIENTS AND METHODS: Retrospective study of the case records of all patients diagnosed with the TINU ...
Courtright P - - 2002
Existing prevalence surveys do not provide adequate information to estimate the magnitude of ocular pathology or vision loss in leprosy patients. We sought to determine the prevalence of ocular findings and related risk factors in leprosy patients at the time of their disease diagnosis. We also sought to determine if ...
Hariprasad Seenu M - - 2002
PURPOSE: Therapeutic decision-making in syphilitic corneal disease is discussed after seeing a patient with keratopathy from congenital syphilis. METHODS: Case report and review of the literature. RESULTS: Laboratory evaluation of our patient revealed a nonreactive serum rapid plasma reagin (RPR) test and a positive microhemagglutination assay-Treponema pallidum (MHA-TP) test. CONCLUSION: ...
Miserocchi Elisabetta - - 2002
PURPOSE: To compare clinical characteristics and outcomes in patients with uveitis caused by herpes simplex virus (HSV) and varicella zoster virus (VZV). DESIGN: Retrospective comparative study. PARTICIPANTS: Forty patients with HSV uveitis and 24 patients with VZV uveitis. METHODS: A retrospective study of 40 patients with HSV and 24 patients ...
Yu C B O - - 2002
Racial variation in the pattern of strabismus is known, but few large scale studies on non-white populations are available. Furthermore, longitudinal change in this pattern within a local setting has not been well documented in the past. This study aims to support the clinical impression that exotropia is more common ...
Weiss Richard A - - 2002
PURPOSE: To determine directly measured vertex distances in a consecutive series of patients refracted at a refractor and to examine the clinical importance of such a measurements for improving refractive surgical results. METHODS: Vertex distance measurements were obtained in 189 consecutive patients by using a new device capable of taking ...
Realini Tony - - 2002
PURPOSE: To describe the frequency and magnitude of asymmetric fluctuations of intraocular pressure (IOP) between fellow eyes of glaucoma patients and normal subjects. DESIGN: Observational case series. PARTICIPANTS: Forty-two subjects without glaucoma and 38 glaucoma patients. METHODS: By means of retrospective chart review, bilateral IOP measurements were examined over time ...
Yilmaz Gürsel - - 2002
The purpose of this study was to quantify aqueous humor nitric oxide levels in patients with Behçet uveitis and age-matched controls to assess how nitric oxide is involved in this ocular condition. Samples of aqueous humor were collected from 11 patients with Behçet uveitis who were undergoing cataract surgery. Sampling ...
Peretz A A Internal Medicine Department, Centre Hospitalier Universitaire Brugmann, Université Libre de Bruxelles, Belgique. - - 2002
Non-infectious uveitis is often associated with systemic diseases severe enough to require corticosteroids (CS) and immunosuppressive drugs, which have potential serious side effects. 28 patients with non-infectious uveitis were referred by the ophthalmologist. A systemic disease was found in 17/28 patients (60%): sarcoidosis in 11, spondylarthropathy in 3, Behcet's disease ...
Bergua Antonio - - 2002
BACKGROUND: The presence of a prominent, retrolental line is shown biomicroscopically. METHODS: A 25-year-old patient with a prominent circular retrolental line is reported. Slit-lamp stereophotographs of the lens were obtained. RESULTS: A prominent, circular, retrolental line was observed in a female patient - who showed no evidence of ocular disease ...
Kotikoski Hanna - - 2002
PURPOSE: To study the role of the L-arginine-nitric oxide (NO) pathway in aqueous humour dynamics by measuring nitrate, nitrite and cyclic (cGMP) levels in guanosine 3',5'-monophosphate the aqueous humour of glaucomatous and nonglaucomatous cataract patients. METHODS: The study involved 38 glaucoma patients undergoing unilateral cataract surgery in the glaucomatous eye ...
Friström Björn - - 2002
PURPOSE: To evaluate a peripheral colour contrast sensitivity test as a tool for early diagnosis of glaucoma in a five-year prospective study. PATIENTS AND METHODS: Peripheral colour contrast sensitivity was measured with a computer graphics system developed by Arden et al. The test colours were varied along the protan, deutan ...
van Kempen-Harteveld M Loes - - 2002
PURPOSE: To assess the degree of visual impairment as a result of cataract formation after total body irradiation (TBI) for bone marrow transplantation. METHODS AND MATERIALS: The data from 93 patients who received TBI in 1 or 2 fractions as a part of their conditioning regimen for bone marrow transplantation ...
Fukuchi Takeo - - 2002
PURPOSE: To report two patients with glaucoma who exhibited severe damage to the corneal endothelium after a trabeculectomy with mitomycin C (MMC). METHODS: This study includes clinical histories and specular microscopic pictures of the cases. RESULTS: Both patients were middle-aged women, underwent trabeculectomy with MMC, had moderate to severe cornea ...
Papa Vincento - - 2002
PURPOSE: To explore the efficacy and safety of 2 concentrations (0.1% and 0.2%) of sodium naproxen ophthalmic solution in controlling ocular inflammation in patients having phacoemulsification and intraocular lens implantation. SETTING: Service d'Ophtalmologie La Pitie' and Centre Ophtalmologique, Paris, and Clinique Sourdille, Nantes, France; Department of Ophthalmology, University of Lausanne, ...
Cengiz M - - 2002
Recent studies show a relationship between oxidants, antioxidants, and degenerative disease of aging like cataract formation. Focal lens cortical changes and cortical liquification have been reported in patients with Down syndrome (DS) over 14 years. There is evidence supporting the hypothesis that trisomy 21 patients have an increase in free ...
Evereklioglu C - - 2002
PURPOSE: To measure central corneal thickness (CCT) in patients with Beh?et's disease (BD), particularly in the active disease. MATERIALS AND METHODS: We measured CCT by ultrasound pachymetry in 64 patients with Beh?et's disease and in 20 healthy controls. Forty-one of the patients with BD had ocular involvement and 23 none; ...
Bayer A U - - 2002
The purpose of the current study was to reveal the occurrence rate of glaucoma among patients with Alzheimer's disease (AD). All 112 patients of four nursing homes in Upper Bavaria, Germany, who met the diagnostic criteria of probable AD, were incorporated into the study. Visual field defects and/or optic disc ...
Kim Wan-Uk - - 2002
PURPOSE: To examine the role of soluble Fas (sFas) in patients with Behcet's uveitis. METHODS: We measured the sFas levels in both sera and aqueous humor (AH) of patients (n = 40) with uveitis and of non-uveitis controls (n = 27) using an enzyme-linked immunosorbent assay. The patients with uveitis ...
Kotaniemi K - - 2002
OBJECTIVE: To compare the activity of arthritis in children with recently diagnosed seronegative oligoarthritis or polyarthritis with or without uveitis. METHODS: The study covered 372 JIA children with recently diagnosed seronegative oligoarthritis or polyarthritis. The mean prospective follow-up period was 4.5 years. Asymptomatic anterior uveitis was found in 96 cases. ...
Levy Y - - 2002
PURPOSE: To assess the prevalence of red and/or blonde hair in a defined pigmentary glaucoma (PG) population and to compare their clinical findings with those of PG patients with black or brown hair. METHODS: Hair color was studied in 35 consecutive PG patients and 35 consecutive primary open angle glaucoma ...
Clouse W Darrin - - 2002
We investigated the demographics, presentation, and outcome of patients undergoing cerebrovascular reconstruction for chronic ocular ischemia (COI) at a single institution through a review of 17 patients over a 9-year period. A total of 558 extracranial cerebrovascular reconstructions were performed during the period of study. Seventeen patients (3%) suffered symptoms ...
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