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Ashaye Adeyinka O - - 2008
PURPOSE: To find the dropout rate and identify the clinical characteristics of patients who drop out in the first year of follow-up from a glaucoma clinic. DESIGN: Descriptive hospital-based study at a tertiary hospital eye department. METHODS: Clinical characteristics of consecutive patients newly diagnosed with glaucoma who dropped out (n=452) ...
Grus F - - 2008
Glaucoma is one of the most frequent causes of blindness worldwide. The elevated intraocular pressure does not explain glaucoma in all patients but can be considered as a risk factor of the disease. There are some evidences that autoimmune mechanisms may be involved in this disorder. This review attempts to ...
Trattler William - - 2008
INTRODUCTION: The aim of this study was to evaluate the incidence of hyperaemia in patients using bimatoprost and to determine if simple interventions result in increased understanding of glaucoma and hyperaemia. METHODS: This was a multicentre, open-label, evaluator-masked clinical trial of 106 patients. Prior to enrolling in the trial, patients ...
Ng Anita S Y - - 2008
PURPOSE: To describe the clinical features and outcomes among contact lens wearers with Fusarium keratitis. METHODS: A retrospective observational review of all cases of culture-proven Fusarium keratitis among contact lens wearers from three hospitals in Hong Kong Island were included. The clinical features, hygiene habits, and clinical outcomes were reviewed. ...
Seo Je Hyun - - 2008
PURPOSE: To investigate the differences in the histopathology and matrix metalloproteinase (MMP) expression in the Tenon's tissue of primary open-angle glaucoma (POAG) patients, primary angle-closure glaucoma (PACG) patients, and non-glaucomatous patients. METHODS: POAG and PACG patients, who underwent a trabeculectomy and had no history of ocular disease except glaucoma, were ...
Reininga J K - - 2008
OBJECTIVE: The aims of this study are to examine in our juvenile idiopathic arthritis (JIA) population: 1) the prevalence and characteristics of uveitis, 2) the complications and outcome of uveitis, 3) prognostic factors, and 4) the adequacy of the current ophthalmologic screening guidelines. METHODS: Retrospective analysis of medical records. RESULTS: ...
Deghislage Catherine - - 2008
To evaluate the rate of false negative results with the Heidelberg Retina Tomograph (HRT II) in a glaucoma practice. Cross-sectional study. We analyzed the HRTs taken between October 2002 and October 2003 in our glaucoma clinic, and selected the patients who had a good quality image (SD < 40 mu) ...
Hossein Attarzadeh; Department of ...
BACKGROUND: This survey was performed to determine the effect of unilateral lateral rectus recession in treatment of moderate angle intermittent exotropia. However, this type of operation and its long term results in patients with moderate angle exotropia have not yet been studied in Iran. METHODS: Forty patients with basic type ...
Chamaillard Mélanie - - 2008
Objectives To describe the clinical features of cutaneous and ocular manifestations of childhood rosacea, to propose diagnostic criteria, and to emphasize the possible severity of ocular complications in this age group. DESIGN: Retrospective study. SETTING: Tertiary referral center. Patients Children aged 1 to 15 years who had received a diagnosis ...
Sobrin Lucia - - 2008
To evaluate the outcomes of treatment with mycophenolate mofetil in patients with scleritis and uveitis refractory to or intolerant of methotrexate. Retrospective noncomparative case series. Eighty-five patients with scleritis and/or uveitis who failed with or did not tolerate methotrexate and were subsequently treated with mycophenolate mofetil between 1998 and 2006. ...
Abu-Amero Khaled K - - 2008
PURPOSE: Glaucoma prevalence can vary geographically and ethnically, which suggests that a genetic element could play a significant role. Studies investigating the role of various mitochondrial haplogroups in the pathogenesis of glaucoma are scarce. METHODS: We compared the prevalence of different mitochondrial haplogroups in 107 glaucoma patients (49 primary open-angle ...
Mabuchi Fumihiko - - 2008
PURPOSE: To assess whether lysyl oxidase-like 1 (LOXL1) polymorphisms are associated with primary open-angle glaucoma (POAG) and exfoliation syndrome (XFS). METHODS: Japanese patients with POAG (n=213) or XFS (n=89) and 191 control subjects were analyzed for LOXL1 polymorphisms (rs1048661: 758G/T, Arg141Leu and rs3825942: 794G/A, Gly153Asp). Demographic and clinical features of ...
Siam Ghada A - - 2008
A retrospective chart review of four patients who had Nd:YAG peripheral iridotomy performed for narrow anterior chamber angle and subsequently developed marked inflammation after tapering anti-inflammatory steroids. These cases were possibly predisposed to this reaction by the heavy pigmentation of their irides based on race, their use of latanoprost, or ...
Ikeda H - - 2008
The clinical significance of a proper eye drop application technique was evaluated in Japanese glaucoma patients. Patients diagnosed with primary open-angle glaucoma having intraocular pressure (IOP) greater than 21 mmHg were treated with eye drops at home. In some patients, however, the topical treatment was ineffective. They returned to the ...
Chiba Tatsuya - - 2008
PURPOSE: To investigate systemic arterial stiffness in glaucoma patients. SUBJECTS AND METHODS: One hundred and forty glaucoma patients and 121 control subjects were enrolled in the study. Among these subjects, 51 glaucoma patients [normal-tension glaucoma (NTG), 31; primary open angle glaucoma or ocular hypertension (POAG/OH): 20] and 61 control subjects ...
Nanke Yuki - - 2008
The current study investigates the role of regulatory T (Treg) cells in the pathogenesis of ocular attack in patients with Behcet's disease (BD). Nineteen BD patients with ocular complications (BDo), including 11 BD patients with ocular attack (BDa) and eight BD patients with inactive ocular complications (BDi), were studied. Four ...
Pasutto Francesca - - 2008
PURPOSE: Mutations in WDR36 were recently reported in patients with adult-onset primary open-angle glaucoma (POAG). In this study, the prevalence of WDR36 variants was investigated in patients with glaucoma who were of German descent with diverse age of onset and intraocular pressure levels. METHODS: Recruited were 399 unrelated patients with ...
Baleriola Jimena - - 2008
We established and validated an in toto method to perform TdT-mediated dUTP nick end labeling to study apoptosis in human trabecular meshwork tissue obtained during trabeculectomy in glaucoma patients. In specimens from patients with primary open-angle glaucoma and primary angle-closure glaucoma, we detected a tendency for more apoptotic cells to ...
Rodríguez-Pérez N N Inmunología, Facultad de Medicina, Universidad Complutense de Madrid, Madrid, - - 2008
We wished to analyse the frequency of Crohn's disease-linked CARD15 polymorphisms (P268S, R702W, G908R and 1007fs) in a group of Spanish patients with idiopathic uveitis. To this aim, DNA samples were obtained from 111 unrelated patients. P268S, R702W and G908R polymorphisms were detected using TaqMan Genotyping kits (Applied Biosystems), and ...
Vardizer Y - - 2007
BACKGROUND: The use of punctal plugs in the treatment of dry eyes is well established. Anophthalmic patients have less tears in the anophthalmic socket in comparison to their normal side, due to an absent corneal reflex (Lee & Elsie, 1981a,b). Many of those patients complain of dry eye symptoms, even ...
Zafar Saemah Nuzhat - - 2007
Xeroderma pigmentosum (XP) is an autosomal recessive (AR) condition characterized by photosensitivity and inability to repair ultra-violet (UV) induced DNA damage. Patients diagnosed with XP, presenting to the Paediatric ophthalmology department of Al-Shifa Trust Eye Hospital, Rawalpindi, were evaluated and followed-up over a period of one year, for the effects ...
Chirapapaisan Niphon - - 2007
To describe the clinical characteristics of orbital pseudotumor, a retrospective analysis was performed on patients with orbital pseudotumor at Siriraj Hospital for ten years. Forty-nine patients (24 males and 25 females; 62 eyes) with a mean age of 43.75 years were included (a mean follow-up of 25 months). Thirty-six patients ...
Chan Stanley M - - 2007
BACKGROUND: We investigated the characteristics and causes of various uveitis subtypes in patients presenting to the Regional Eye Centre at the Royal Alexandra Hospital, University of Alberta, Edmonton, Alta., and estimated the incidence of anterior uveitis in northern Alberta. METHODS: A retrospective study was conducted of all patients presenting with ...
Lew Helen - - 2007
PURPOSE: This study examined the rate of binocular photophobia in intermittent exotropia patients before surgical correction, and the factors affecting this rate. The study also investigated the factors affecting postsurgical disappearance of binocular photophobia. METHODS: The study involved 162 basic type intermittent exotropia patients who underwent surgical correction between March ...
Kotaniemi Kaisu - - 2007
To describe the development and management of ocular hypertension (OHT) and secondary glaucoma (SG) in patients with juvenile idiopathic arthritis (JIA)-associated uveitis. A series of 104 patients with newly diagnosed JIA and associated uveitis was collected in 1989-1996. A re-evaluation was made after mean 9.7 years (range 0.8-15.6 years) follow-up. ...
Plummer Caryn E - - 2007
Small animal patients with endocrinopathies are at risk of developing many ophthalmic conditions resulting from endocrine hormone imbalances. Diabetic animals frequently develop cataracts but can also have numerous other ocular problems, including uveitis, keratopathy, retinopathy, and the effects of lipid derangements and systemic hypertension. Cushing's patients can develop complications from ...
Onal Sumru - - 2008
PURPOSE: To investigate spatial-contrast sensitivity (CS) assessment as a tool for diagnosis of early glaucoma in patients with good visual acuity. METHODS: In this prospective cross-sectional study we evaluated one eye of 50 patients with primary open angle or normotensive glaucoma who were newly diagnosed. All met the 0.6, or ...
Norrsell Kerstin - - 2008
PURPOSE: To carry out a longitudinal study of patients with Fuchs' heterochromic uveitis (FHU) in western Sweden and to establish the factors responsible for diagnostic delay. METHODS: A sample of 54 patients, 51 with monocular and three with binocular FHU, were followed for periods ranging from 8 months to 15 ...
Scoper Stephen V - - 2007
This 28-d, open-label, multicenter, single-arm clinical study was designed to evaluate perceptions of olopatadine 0.2% in patients with active ocular allergic signs and symptoms. The study enrolled 330 patients, 5 to 94 y of age, who had previously used olopatadine 0.1% for active allergic conjunctivitis. Most patients were white (n=230; ...
Chalmers Robin L - - 2007
INTRODUCTION: Clinical studies that occur before and after the regulatory approval of contact lenses differ in many aspects, including breadth, length, and subject inclusion and exclusion criteria. METHODS: A sample of published studies conducted in North America was reviewed to outline these differences and show their impact on rates of ...
Motolese E - - 2007
PURPOSE: Eye involvement has long been appreciated in patients with chronic graft versus host disease (cGVHD). In particular, ocular complications are frequent and can be potentially severe in patients with steroid-refractory cGVHD, and therefore necessitate close monitoring. This prospective study was designed to describe eye manifestations of cGVHD in a ...
Tosaka Karin - - 2007
PURPOSE: Heat-shock proteins (HSPs) or antibodies against them may contribute to glaucomatous optic neuropathy. We investigated the associations of HSP70-1 polymorphisms with open-angle glaucoma (OAG) in a Japanese population. METHODS: In 241 normal Japanese controls and 501 Japanese OAG patients, including 211 with primary open-angle glaucoma (POAG) and 290 with ...
Chung Yu-Mei - - 2007
BACKGROUND: The aim of this study was to assess the clinical features of uveitis with biopsy-proven sarcoidosis in Chinese patients. METHODS: This was a retrospective study of uveitis patients with biopsy-proven sarcoidosis who consecutively visited the uveitis clinic of Taipei Veterans General Hospital from 1986 to 2005. Medical records were ...
Amaro Miguel Hage - - 2007
PURPOSE: To report the findings of indocyanine green angiography performed in patients with recurrent ocular toxoplasmosis. METHODS: Institutional prospective analysis of 23 eyes from 23 immunocompetent patients with recurrent ocular toxoplasmosis aged between 17 and 41 years. These patients underwent a complete ocular examination including indocyanine green angiography. RESULTS: Multiple ...
Ali Amro - - 2007
PURPOSE OF REVIEW: Ocular inflammation is a common and important manifestation of disease in patients with seronegative spondyloarthropathy. RECENT FINDINGS: Anterior uveitis is among the most common manifestations of eye disease in patients with seronegative spondyloarthropathies. Additionally, a strong correlation exists among such affected patients and the presence of the ...
Wolf Eric Jay - - 2007
We describe a patient with systemic graft-versus-host disease who developed a nonhealing epithelial defect after cataract surgery that healed on cessation of a topical nonsteroidal antiinflammatory drug (NSAID) (ketorolac). The patient developed a central corneal perforation in the fellow eye while on a new NSAID formulation (nepafenac) after routine cataract ...
Andrikopoulos G K - - 2009
PURPOSE: To investigate the prevalence of glaucoma and coronary artery disease (CAD) in patients with cataract and pseudoexfoliation (PEX) syndrome. METHODS: Cross-sectional study of 2140 consecutive patients with cataract admitted at the University Hospital of Patras, Greece, for cataract surgery. Only patients with senile cataract were included in this study. ...
Galor Anat - - 2007
PURPOSE: To evaluate the rates of adverse ocular events after intravitreal triamcinolone acetonide (IVTA) injection in patients with and without uveitis. DESIGN: Retrospective observational case series. PARTICIPANTS: Two hundred twenty-two eyes of 173 patients were included in the study: 45 eyes of 31 patients with macular edema (ME) due to ...
Boura P - - 2007
OBJECTIVE-METHODS: Adamantiades-Behcet disease (ABD) is a multi-systemic vasculitis of unknown origin, with a characteristic geographic distribution, that affects vessels of all kinds and sizes and is characterized by recurrent mucosal, skin and ocular lesions. In the present study, a series of 36 patients from Northern Greece is analyzed retrospectively in ...
Kaya Vedat - - 2007
PURPOSE:: To analyze the differences in corneal topography in keratoconus patients with and without atopy. METHODS:: In the Beyoglu Eye Research and Training Hospital Refractive Surgery Department, corneal examination with the Orbscan II device (Bausch & Lomb) was done to all patients between May and June 2004 who were diagnosed ...
Enock Malachi E - - 2007
OBJECTIVE: To determine the risk factors, and the pattern of ocular trauma in Irrua, a sub-urban community in Edo State, Nigeria. METHODS: A prospective study of all cases of ocular trauma seen in the Irrua Specialist Teaching Hospital, Irrua, Nigeria from January to December 2005. The age, gender, occupation, activity ...
Fimiani F - - 2007
PURPOSE: This study identifies the incidence of primary ocular pathologies in a population of Italian children with Down syndrome. METHODS: A total of 157 Italian children with Down syndrome, age between 1 month and 18 years, were screened between February 2005 and October 2006. The ophthalmologic evaluation included a global ...
Yang Peizeng - - 2008
PURPOSE: To characterize the clinical features of Behçet's disease in Chinese patients. DESIGN: Retrospective noncomparative case series. PARTICIPANTS: Seven hundred seventy-five eyes of 437 patients with Behçet's disease initially examined from August, 1995, through June, 2006. METHODS: The history, demographic parameters, and clinical findings of all consecutive Behçet's patients referred ...
Karakucuk Sarper - - 2008
BACKGROUND: Sleep-related disorders are among the important risk factors for neurovascular diseases. Obstructive sleep apnea syndrome (OSAS) is characterized by snoring, excessive daytime sleepiness, and insomnia. Our aim was to investigate the presence of glaucoma in patients with OSAS and to reveal vascular pathology related to the pathogenesis of glaucoma ...
Parc Christine E - - 2007
OBJECTIVES: To review cases of ocular syphilis presenting to a tertiary uveitis clinic during a syphilis epidemic in France between January 2001 and January 2004. STUDY DESIGN: Retrospective chart and patient database review. RESULTS: Ten patients who presented with symptoms and signs of uveitis tested positive for active syphilis. Some ...
Pappachan Joseph M JM Department of Medicine, Calicut Medical College, India. - - 2007
Uveitis is increasingly being reported from south India following epidemics of leptospirosis. The incidence of eye involvement in treated patients has not been investigated properly in prospective studies. To determine the incidence, clinical spectrum and risk factors for Leptospiral uveitis in antibiotic-treated patients. A prospective cohort study conducted among the ...
Khanna Aman - - 2007
PURPOSE: Sarcoidosis is increasingly diagnosed in developing countries, although it was earlier thought to be uncommon. We describe the pattern of ocular manifestations in sarcoidosis in India. METHODS: A total of 48 consecutive patients with histologically confirmed sarcoidosis, referred to a teaching university hospital, underwent a detailed ophthalmological examination, irrespective ...
Takahide Kikuchi - - 2007
Keratoconjunctivitis sicca (KCS) occurs in 40%-60% of patients with chronic graft-versus-host-disease (cGVHD) after allogeneic hematopoietic cell transplantation. Although immunosuppressive therapy is the primary treatment of chronic GVHD, ocular symptoms require measures to improve ocular lubrication, decrease inflammation, and maintain mucosal integrity. The liquid corneal bandage provided by a fluid-ventilated, gas-permeable ...
Larakeb Anis - - 2007
Factor H deficiency is responsible for thrombotic microangiopathy (TMA) via uncontrolled activation of the alternative pathway of the complement system. Ocular TMA has never been reported in patients with factor H abnormalities. A male patient with congenital homozygote factor H deficiency reached end-stage renal disease at the age of 10 ...
Pierre Andrena - - 2007
PURPOSE: To determine whether yellow-tinted intraocular lenses (IOLs) negatively affect luminance contrast in postoperative cataract patients. SETTING: Department of Ophthalmology, Sir Mortimer B. Davis Jewish General Hospital, McGill University, Montreal, Quebec, Canada. METHODS: Luminance contrast was measured using the minimum-motion technique. The stimulus consisted of blue and red sinusoidal gratings ...
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